Efficient recombinant III-type humanized collagen preparation device

Abstract

The utility model discloses an efficient recombinant III type humanized collagen preparation device, which belongs to the technical field of collagen preparation, and comprises a stirring barrel and a stirring assembly, the outer side of the stirring barrel is sleeved with a fixing frame, the top of the stirring barrel is provided with a motor box, the stirring assembly is arranged in the stirring barrel, and the motor box is connected with the motor box. Supporting legs are arranged at the bottom of the fixing frame. According to the device disclosed by the utility model, fine particle raw materials left after crushing can be further ground while raw materials are stirred through the arranged stirring assembly, so that the raw materials are fully utilized, and resource waste during preparation is prevented; during stirring, residual particles in raw materials can be ground when the lower grinding plate and the upper grinding plate are in contact with the upper grinding plate and the lower grinding plate, and the raw materials are continuously stirred by a stirring rod and a stirring plate under the action of a motor during grinding, so that the mixing effect of the raw materials can be improved, and the raw materials are mixed more uniformly.

Description

Technical Field

[0001] The utility model belongs to the technical field of collagen preparation, and particularly relates to a device for preparing highly efficient recombinant type III humanized collagen. Background Technique

[0002] Compared with traditional animal-derived collagen, recombinant type III humanized collagen can obtain a higher-purity collagen product through recombinant technology, reducing impurities and potential immunogenic risks. After design and optimization, its structure is closer to human own collagen, with good biocompatibility and biological activity.

[0003] In the preparation process, first, it is pretreated to remove impurities in the raw materials, then the raw materials are crushed, and then the crushed raw materials are stirred and mixed. In the existing recombinant type III humanized collagen, a large number of fine particles often remain during crushing, which are difficult to handle and are often removed as impurities, resulting in waste of resources. Therefore, a device for preparing highly efficient recombinant type III humanized collagen is needed to solve the above problems. Content of the Utility Model

[0004] The purpose of the utility model is to provide a device for preparing highly efficient recombinant type III humanized collagen to solve the problems raised in the above background technique.

[0005] To achieve the above purpose, the utility model provides the following technical solution: A device for preparing highly efficient recombinant type III humanized collagen, including a stirring barrel and a stirring component. A fixed frame is sleeved outside the stirring barrel. A motor box is arranged at the top of the stirring barrel. A stirring component is arranged inside the stirring barrel. Support legs are arranged at the bottom of the fixed frame. The stirring component includes a motor, a stirring roller, stirring rods, stirring plates, a scraper, a lower grinding plate, a connecting plate, an upper grinding plate, and a limiting plate. The output end of the motor is provided with the stirring roller. A stirring rod is arranged on one side of the stirring roller. One end of the stirring rod is provided with a stirring plate. A scraper is arranged on one side of the stirring plate. A lower grinding plate is arranged at the bottom of the stirring plate. An upper grinding plate is arranged at the top of the stirring plate. The lower grinding plate at the bottom of one of the stirring plates is connected to the upper grinding plate at the top of the other stirring plate through the connecting plate. A limiting plate is arranged on one side of the connecting plate.

[0006] As a preferred implementation manner, the number of the stirring rods is twelve, and the number of the stirring plates is four. One end of each stirring rod is connected to two of the stirring plates.

[0007] As a preferred implementation manner, the scraper is an arc-shaped plate and is made of rubber material.

[0008] As a preferred embodiment, the outer side of the motor is connected to the motor box, and one side of the scraping plate is connected to the inner wall of the stirring barrel.

[0009] As a preferred embodiment, the inner wall of the stirring barrel is provided with an upper grinding plate and a lower grinding plate, and a limiting plate is connected between the upper grinding plate and the lower grinding plate.

[0010] As a preferred embodiment, the top of the stirring barrel is provided with a feeding port, the bottom of the stirring barrel is provided with a discharging port, the discharging port is inclined, and the bottom of the supporting leg is provided with shock pads, and the number of the shock pads is three.

[0011] Compared with the prior art, the beneficial effects of the present utility model are:

[0012] In the present utility model, through the arranged stirring assembly, while stirring the raw materials, the small particle raw materials left after crushing can be further ground, so that the raw materials are fully utilized, and waste of resources during preparation is prevented. When the lower grinding plate and the upper grinding plate are in contact with the upper grinding plate and the lower grinding plate during stirring, the residual particles in the raw materials can be ground. While grinding, the stirring rod and the stirring plate continuously stir the raw materials under the action of the motor, which can improve the mixing effect of the raw materials and make the raw materials more evenly mixed.

[0013] In the present utility model, by arranging a scraping plate on one side of the stirring plate, the inner wall of the stirring barrel can be cleaned, preventing the raw materials from adhering to the inner wall of the stirring barrel for a long time and being difficult to clean, thereby affecting the stirring work of the next barrel of raw materials. By arranging the stirring rod and the stirring plate, the raw materials can be stirred horizontally and vertically at the same time, greatly improving the stirring efficiency of the raw materials, making the raw materials more evenly mixed, and facilitating the subsequent preparation of recombinant type III humanized collagen. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 is a schematic diagram of the three-dimensional structure of the stirring barrel of the present utility model;

[0015] Figure 2 is a schematic diagram of the three-dimensional sectional structure of the stirring barrel of the present utility model;

[0016] Figure 3 is a schematic diagram of the three-dimensional structure of the stirring assembly of the present utility model;

[0017] Figure 4 is a schematic diagram of the three-dimensional structure of the stirring plate of the present utility model;

[0018] Figure 5 is the present utility model Figure 3 Schematic diagram of the enlarged three-dimensional structure of A in.

[0019] In the figure: 1, stirring barrel; 2, fixing frame; 3, motor box; 4, stirring assembly; 5, support leg; 6, feeding port; 7, discharging port; 8, shock pad; 9, upper grinding plate; 10, lower grinding plate; 301, motor; 302, stirring roller; 303, stirring rod; 304, stirring plate; 305, scraping plate; 306, lower grinding plate; 307, connecting plate; 308, upper grinding plate; 309, limiting plate. Detailed implementation mode

[0020] The present utility model will be further described below in conjunction with embodiments.

[0021] The following embodiments are used to illustrate the present utility model, but cannot be used to limit the protection scope of the present utility model. The conditions in the embodiments can be further adjusted according to specific conditions. Any simple improvement of the method of the present utility model under the premise of the concept of the present utility model belongs to the protection scope required by the present utility model.

[0022] Please refer to Figures 1 - 5 , the present utility model provides a device for preparing highly efficient recombinant type III humanized collagen, including a stirring barrel 1 and a stirring assembly 4. A fixing frame 2 is sleeved outside the stirring barrel 1. A motor box 3 is arranged at the top of the stirring barrel 1. A stirring assembly 4 is arranged inside the stirring barrel 1. Support legs 5 are arranged at the bottom of the fixing frame 2. The stirring assembly 4 includes a motor 301, a stirring roller 302, a stirring rod 303, a stirring plate 304, a scraping plate 305, a lower grinding plate 306, a connecting plate 307, an upper grinding plate 308 and a limiting plate 309. The output end of the motor 301 is provided with the stirring roller 302. A stirring rod 303 is arranged on one side of the stirring roller 302. A stirring plate 304 is arranged at one end of the stirring rod 303. A scraping plate 305 is arranged on one side of the stirring plate 304. A lower grinding plate 306 is arranged at the bottom of the stirring plate 304. An upper grinding plate 308 is arranged at the top of the stirring plate 304. The lower grinding plate 306 at the bottom of one stirring plate 304 is connected to the upper grinding plate 308 at the top of the other stirring plate 304 through the connecting plate 307. A limiting plate 309 is arranged on one side of the connecting plate 307. By controlling the motor 301 to drive the stirring roller 302 to rotate, the stirring rod 303 can be driven to rotate, so as to drive the stirring plate 304 to rotate. Further, the lower grinding plate 306 and the upper grinding plate 308 can be brought into contact with the upper grinding plate 9 and the lower grinding plate 10, so as to grind the residual particles in the raw materials. While grinding, the stirring rod 303 and the stirring plate 304 continuously stir the raw materials under the action of the motor 301. During the stirring process, the scraping plate 305 can clean the inner wall of the stirring barrel 1.

[0023] The number of the stirring plates 304 is four, and one end of each stirring rod 303 is connected to two stirring plates 304.

[0024] The scraping plate 305 is an arc-shaped plate, and the scraping plate 305 is made of rubber material.

[0025] The outer side of the motor 301 is connected to the motor box 3, and one side of the scraper 305 is connected to the inner wall of the stirring barrel 1.

[0026] The inner wall of the stirring barrel 1 is provided with an upper grinding plate 9 and a lower grinding plate 10, and a limiting plate 309 is connected between the upper grinding plate 9 and the lower grinding plate 10.

[0027] The top of the stirring barrel 1 is provided with a feeding port 6, the bottom of the stirring barrel 1 is provided with a discharging port 7, the discharging port 7 is inclined, and the bottom of the support leg 5 is provided with shock pads 8. The number of the shock pads 8 is three. By arranging the stirring rod 303 and the stirring plate 304, the raw materials can be stirred horizontally and vertically at the same time, greatly improving the stirring efficiency of the raw materials. By setting the scraper 305 to be arc-shaped, the contact area between the scraper 305 and the inner wall of the stirring barrel 1 can be increased, so that the scraper 305 can better scrape the raw materials on the inner wall of the stirring barrel 1. By setting the scraper 305 to be made of rubber material, it can prevent the scraper 305 from damaging the stirring barrel 1 when contacting the inner wall of the stirring barrel 1, so as to scrape out metal impurities and affect the use of the raw materials. By arranging the fixing frame 2 and the shock pads 8, the stirring barrel 1 can be protected to a certain extent, preventing it from falling off and being damaged during the stirring process, resulting in certain economic losses.

[0028] The working principle and usage process of the present utility model are as follows: First, the pre-treated and crushed recombinant type III humanized collagen raw materials are added into the stirring barrel 1 through the feeding port 6 through the feeding port 7. Then, the motor 301 is controlled to drive the stirring roller 302 to rotate, which can make the stirring rod 303 rotate, thereby driving the stirring plate 304 to rotate, and further making the lower grinding plate 306 and the upper grinding plate 308 contact the upper grinding plate 9 and the lower grinding plate 10, so as to grind the remaining particles in the raw materials. While grinding, the stirring rod 303 and the stirring plate 304 continuously stir the raw materials under the action of the motor 301. During the stirring process, the scraper 305 can clean the inner wall of the stirring barrel 1. Finally, when the raw materials are fully mixed, the stirring assembly 3 is continuously turned on, and the discharging port is opened. During the discharging process, the scraper 305 arranged on one side of the stirring plate 304 can scrape the inner wall of the stirring barrel 1, so that all the raw materials mixed in the stirring barrel can flow out and enter the next process.

[0029] Although the embodiments of the present utility model have been shown and described, for those of ordinary skill in the art, it can be understood that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principle and spirit of the present utility model. The scope of the present utility model is defined by the appended claims and their equivalents.

Claims

1. An apparatus for preparing highly efficient recombinant type III humanized collagen, comprising a stirring barrel (1) and a stirring assembly (4), characterized in that: A fixing frame (2) is sleeved outside the stirring barrel (1). A motor box (3) is provided at the top of the stirring barrel (1). A stirring assembly (4) is provided inside the stirring barrel (1). Support legs (5) are provided at the bottom of the fixing frame (2). The stirring assembly (4) includes a motor (301), a stirring roller (302), stirring rods (303), stirring plates (304), a scraping plate (305), a lower grinding plate (306), a connecting plate (307), an upper grinding plate (308) and a limiting plate (309). The output end of the motor (301) is provided with the stirring roller (302). One side of the stirring roller (302) is provided with the stirring rods (303). One end of each stirring rod (303) is provided with a stirring plate (304). One side of the stirring plate (304) is provided with the scraping plate (305). The bottom of the stirring plate (304) is provided with the lower grinding plate (306). The top of the stirring plate (304) is provided with the upper grinding plate (308). The lower grinding plate (306) at the bottom of one of the stirring plates (304) is connected to the upper grinding plate (308) at the top of the other stirring plate (304) through the connecting plate (307). A limiting plate (309) is provided on one side of the connecting plate (307).

2. The preparation device of highly efficient recombinant type III humanized collagen according to claim 1, wherein: The number of the stirring rods (303) is twelve, and the number of the stirring plates (304) is four. One end of each stirring rod (303) is connected to two of the stirring plates (304).

3. The preparation device of highly efficient recombinant type III humanized collagen according to claim 1, characterized in that: The scraping plate (305) is an arc-shaped plate, and the scraping plate (305) is made of rubber material.

4. The preparation device for highly efficient recombinant type III humanized collagen according to claim 1, characterized in that: The outside of the motor (301) is connected to the motor box (3), and one side of the scraping plate (305) is connected to the inner wall of the stirring barrel (1).

5. The preparation device for highly efficient recombinant type III humanized collagen according to claim 1, wherein: An upper grinding plate (9) and a lower grinding plate (10) are provided on the inner wall of the stirring barrel (1), and the upper grinding plate (9) and the lower grinding plate (10) are connected to the limiting plate (309).

6. The preparation device for highly efficient recombinant type III humanized collagen according to claim 1, wherein: A feeding port (6) is provided at the top of the stirring barrel (1). A discharging port (7) is provided at the bottom of the stirring barrel (1). The discharging port (7) is inclined. Shock-absorbing pads (8) are provided at the bottom of the support legs (5), and the number of the shock-absorbing pads (8) is three.

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