Cell sap sample processing device

By designing a cell fluid sample processing device, using the combination of aspiration and flow guide, the integration of cell suspension homogenization and waste liquid removal steps is solved, and the efficiency and accuracy of cell concentration detection are improved.

CN223078149UActive Publication Date: 2025-07-08SUZHOU SHUANGCAI BIOTECHNOLOGY CO LTD
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202421450582.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-24
Publication Date
2025-07-08
Estimated Expiration
2034-06-24

AI Technical Summary

Technical Problem

The prior art cannot effectively integrate the homogenization treatment and waste liquid removal steps of cell suspension, resulting in low cell concentration detection efficiency.

Method used

A cell fluid sample processing device is designed, including a tube body, a moving assembly, a suction piece and a flow guide. By moving assembly, the tube body is driven close to or away from the sample tube, and the suction piece and the flow guide are used to achieve uniform distribution of the cell suspension and the derivation of waste liquid.

Benefits of technology

The efficiency and accuracy of cell concentration detection are improved, and through the combination of suction parts and flow guides, uniform mixing of cell suspensions and efficient treatment of waste liquids are achieved.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN223078149U_ABST
    Figure CN223078149U_ABST
Patent Text Reader

Abstract

The utility model discloses a cell sap sample processing device which comprises a tube body, a moving assembly, a suction part and a flow guide part, and the moving assembly drives the tube body to be close to or far away from a sample tube; when the suction piece is communicated with the tube body, the suction piece enables the cell sap in the sample tube to enter or leave the tube body in a reciprocating manner; when the flow guide part is communicated with the tube body, the flow guide part is used for guiding out waste liquid in the sample tube through the tube body. According to the cell sap sample treatment device disclosed by the utility model, in a cell detection process, cell suspension in the sample tube can be sucked into the tube body and discharged out of the tube body through the suction piece, so that the cell suspension forms turbulent flow, and cells are uniformly distributed in the cell suspension; after the detection is completed, the cell waste liquid in the sample tube can be guided out through the flow guide piece and the tube body. Therefore, the cell concentration detection efficiency can be effectively improved.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The utility model belongs to the technical field of cell detection, and particularly relates to a cell liquid sample processing device. Background Art

[0002] In cell biology research experiments, it is necessary to detect the concentration (quantitative counting) of cells or other biological particles. The concentration of cell suspension is not only a monitoring parameter for cell culture, but also a necessary parameter in many experimental projects, which affects the smooth completion of biological research experiments.

[0003] Cell detectors usually use the Coulter principle to detect the cell concentration in cell suspension. Before detection, it is necessary to homogenize the cell suspension in the sample tube so that the cells are evenly distributed in the liquid to ensure the accuracy of subsequent detection results. After detection, it is necessary to remove the waste liquid after detection from the sample tube for centralized treatment of the waste liquid. In the prior art, the steps of mixing the cell suspension and removing the cell waste liquid cannot be integrated, resulting in relatively low detection efficiency.

[0004] Therefore, in view of the above technical problems, it is necessary to provide a cell liquid sample processing device. Summary of the Utility Model

[0005] The purpose of the utility model is to provide a cell liquid sample processing device, which can solve the problem of relatively low cell counting detection efficiency mentioned above.

[0006] In order to achieve the above purpose, the technical solution provided by a specific embodiment of the utility model is as follows:

[0007] A cell liquid sample processing device includes a tube body, a moving component, a suction component and a diversion component. The moving component drives the tube body to approach or move away from the sample tube; when the suction component is communicated with the tube body, the suction component makes the cell liquid in the sample tube reciprocally enter or leave the tube body; when the diversion component is communicated with the tube body, the diversion component exports the waste liquid in the sample tube through the tube body.

[0008] In one or more embodiments of the utility model, the moving component includes: a fixing plate; a driving member installed on the fixing plate; a connecting plate slidably connected with the fixing plate and fixedly connected with the output end of the driving member, and the tube body is installed at one end of the connecting plate away from the driving member so that the tube body is aligned with the orifice of the sample tube

[0009] In one or more embodiments of the present utility model, the moving assembly further includes a bottom block and a pressing block. The bottom block is fixedly connected to one end of the connecting plate away from the driving member. An installation hole for abutting and fixing the tube body is formed between the pressing block and the bottom block, and the pressing block is detachably connected to the bottom block.

[0010] In one or more embodiments of the present utility model, the moving assembly further includes a limiting member for limiting the moving direction of the tube body.

[0011] In one or more embodiments of the present utility model, the limiting member includes a limiting block. The limiting block is fixedly connected to the fixing plate. The limiting block is provided with a limiting hole, and the tube body slidably passes through the limiting hole.

[0012] In one or more embodiments of the present utility model, the fixing plate is provided with an avoidance notch on the side away from the driving member.

[0013] In one or more embodiments of the present utility model, the end of the tube body close to the sample tube is necked down to form a spike portion.

[0014] In one or more embodiments of the present utility model, the cell liquid sample processing device further includes a first pipeline connecting the suction member and the tube body, a second pipeline connecting the diversion member and the tube body, and a control member for controlling the opening and closing of the first pipeline or the second pipeline.

[0015] In one or more embodiments of the present utility model, the control member includes a solenoid valve, and the solenoid valves are respectively installed on the first pipeline and the second pipeline.

[0016] In one or more embodiments of the present utility model, the suction member is an injection pump.

[0017] Compared with the prior art, during the cell detection process of the cell liquid sample processing device of the present utility model, the cell suspension in the sample tube can be sucked into and discharged from the tube body by the suction member, so that the cell suspension forms a turbulent flow, thereby enabling the cells to be evenly distributed in the cell suspension. The cell waste liquid in the sample tube can be discharged through the diversion member and the tube body, thus facilitating the centralized treatment of the cell waste liquid. Therefore, the present utility model can effectively improve the detection efficiency of the cell concentration. Description of the Drawings

[0018] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings required for the description of the embodiments or the prior art. Obviously, the drawings in the following description are only some embodiments recorded in the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can be obtained based on these drawings.

[0019] Figure 1 It is a schematic structural diagram of a cell fluid sample processing device in an embodiment of the present invention;

[0020] Figure 2 It is a schematic structural diagram of another perspective of the cell fluid sample processing device in an embodiment of the present invention;

[0021] Figure 3 is Figure 2 the enlarged schematic diagram at A in

[0022] Main reference numerals description:

[0023] 1. Tube body; 11. Spiked part; 2. Moving assembly; 21. Fixed plate; 22. Driving member; 23. Connecting plate; 24. Bottom block; 25. Pressing block; 26. Limiting member; 261. Limiting block; 3. Suction member; 4. Diversion member; 5. Mounting hole. Detailed implementation manners

[0024] In order to enable those skilled in the art to better understand the technical solutions in the present invention, the following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0025] Refer to Figure 1 , the cell fluid sample processing device in an embodiment of the present invention includes a tube body 1, a moving assembly 2, a suction member 3, and a diversion member 4. The moving assembly 2 drives the tube body 1 to approach or move away from a sample tube (the sample tube is not shown in the figure). When the suction member 3 is communicated with the tube body 1, the suction member 3 enables the cell fluid in the sample tube to reciprocally enter or leave the tube body 1. When the diversion member 4 is communicated with the tube body 1, the diversion member 4 discharges the waste liquid in the sample tube through the tube body 1.

[0026] Refer to Figure 2In the process of detecting the concentration of the cell fluid, the suction piece 3 is first connected to the tube body 1, and then the moving component 2 drives the tube body 1 close to the sample tube, and one end of the tube body 1 is submerged in the liquid surface. Then the suction piece 3 is started to circulate and suck the cell suspension in the sample tube, so that the cell suspension reciprocates into or leaves the tube body 1 with a smaller diameter, so that the cell suspension forms turbulence, so that the cells are evenly distributed in the cell suspension, so as to improve the accuracy of subsequent cell concentration detection. After uniform mixing, the moving component 2 drives the tube body 1 away from the sample tube. In this embodiment, the suction piece 3 is a syringe pump.

[0027] After the cell fluid concentration detection is completed, the flow guide 4 is switched to be connected with the tube body 1, and then the moving assembly 2 drives the tube body 1 to move into the sample tube, and then the flow guide 4 is started to guide the cell waste fluid in the sample tube. In this embodiment, the flow guide 4 can be a hydraulic pump.

[0028] It is understandable that the connection between the tube body 1 and the suction member 3 or the flow guide member 4 can be switched manually by relevant personnel, or can be switched automatically by setting a mechanical device.

[0029] Reference Figure 2 and Figure 3 The tube body 1 is constricted at one end near the sample tube to form a spike portion 11. The spike portion 11 further reduces its caliber, thereby further improving the uniform mixing effect of the cells in the cell suspension. When the guide member 4 draws cell waste liquid from the sample tube, the spike portion 11 can also enhance the suction effect, thereby improving the removal efficiency of the cell waste liquid.

[0030] Reference Figure 2 and Figure 3 The moving assembly 2 includes a fixing plate 21 , a driving member 22 , a connecting plate 23 , a bottom block 24 , a pressing block 25 and a limiting member 26 .

[0031] Reference Figure 2 and Figure 3 , the driving member 22 is installed on the fixed plate 21, and the driving member 22 can be a cylinder. The fixed plate 21 is provided with a notch for avoidance on the side away from the driving member 22. On the one hand, the notch can effectively save material costs, and on the other hand, it can avoid other devices and facilitate installation. The connecting plate 23 is slidably connected to the fixed plate 21, and is fixedly connected to the output end of the driving member 22. The connecting plate 23 and the fixed plate 21 can be slidably connected via a slide rail. The tube body 1 is installed on one end of the connecting plate 23 away from the driving member 22, so that the tube body 1 is aligned with the tube mouth of the sample tube. Therefore, the driving member 22 drives the connecting plate 23 to move, thereby being able to drive the tube body 1 to approach or move away from the sample tube.

[0032] Reference Figure 2 and Figure 3The bottom block 24 is fixedly connected to the end of the connecting plate 23 away from the driving member 22, and a mounting hole 5 for abutting and fixing the pipe body 1 is formed between the pressing block 25 and the bottom block 24, and the pressing block 25 and the bottom block 24 are detachably connected. The combination of the bottom block 24 and the pressing block 25 can effectively fix the pipe body 1.

[0033] Reference Figure 3 The limiting member 26 is used to limit the moving direction of the tube body 1, so that the tube body 1 moves toward or away from the sample tube. Specifically, the limiting member 26 includes a limiting block 261, which is fixedly connected to the fixing plate 21. The limiting block 261 is provided with a limiting hole, and the tube body 1 is slidably arranged in the limiting hole. The limiting block 261 can also reduce the shaking that may occur during the movement of the tube body 1, and further ensure the stability of the movement of the tube body 1.

[0034] Reference Figure 1 In an optional embodiment, the cell fluid sample processing device further includes a first pipeline connecting the suction member 3 and the tube body 1, a second pipeline connecting the flow guide member 4 and the tube body 1, and a control member for controlling the opening and closing of the first pipeline or the second pipeline. In this embodiment, the control member includes a solenoid valve, which is installed in the first pipeline and the second pipeline respectively. The first pipeline, the second pipeline and the solenoid valve are not shown in the figure.

[0035] When the electromagnetic valve in the first pipeline is opened, the suction member 3 is connected to the tube body 1, so that the cell suspension can be mixed. When the electromagnetic valve in the second pipeline is opened, the flow guide member 4 is connected to the tube body 1, so that the cell waste liquid can be extracted and discharged.

[0036] Therefore, by providing a controller, the connection state between the suction member 3 or the flow guide member 4 and the tube body 1 can be automatically switched, thereby further improving the detection efficiency of the cell suspension.

[0037] It is obvious to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above, and that the present invention can be implemented in other specific forms without departing from the spirit or essential features of the present invention. Therefore, the embodiments should be regarded as exemplary and non-restrictive from any point of view, and the scope of the present invention is defined by the appended claims rather than the above description, and it is intended that all changes falling within the meaning and scope of the equivalent elements of the claims be included in the present invention. Any reference numeral in a claim should not be regarded as limiting the claim to which it relates.

[0038] In addition, it should be understood that although this specification is described in terms of embodiments, not every embodiment contains only one independent technical solution. This narrative manner of the specification is only for clarity. Those skilled in the art should regard the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. A cell sap sample processing device, characterized in that, Comprising: A tube body (1); A moving component (2) for driving the tube body (1) to approach or move away from the sample tube; A suction component (3), when the suction component (3) is in communication with the tube body (1), the suction component (3) enables the cell fluid in the sample tube to reciprocally enter or leave the tube body (1); A diversion component (4), when the diversion component (4) is in communication with the tube body (1), the diversion component (4) discharges the waste liquid in the sample tube through the tube body (1).

2. The cell sap sample processing device according to claim 1, wherein The moving component (2) comprises: A fixing plate (21); A driving component (22) installed on the fixing plate (21); A connecting plate (23) slidably connected to the fixing plate (21) and fixedly connected to the output end of the driving component (22), the tube body (1) is installed at one end of the connecting plate (23) away from the driving component (22) so that the tube body (1) is aligned with the orifice of the sample tube.

3. The cell sap sample processing device according to claim 2, wherein, The moving component (2) further comprises a bottom block (24) and a pressing block (25), an installation hole (5) for abutting and fixing the tube body (1) is formed between the bottom block (24) and the pressing block (25), and the pressing block (25) is detachably connected to the bottom block (24).

4. The cell sap sample processing device according to claim 2, characterized in that The moving component (2) further comprises a limiting component (26) for limiting the moving direction of the tube body (1).

5. The cell sap sample processing device according to claim 4, characterized in that, The limiting component (26) comprises a limiting block (261) fixedly connected to the fixing plate (21), the limiting block (261) is provided with a limiting hole, and the tube body (1) slidably passes through the limiting hole.

6. The cell sap sample processing device according to claim 2, characterized in that, The fixing plate (21) is provided with an avoidance notch on the side away from the driving component (22).

7. The cell sap sample processing device according to claim 1, characterized in that, One end of the tube body (1) close to the sample tube is necked down to form a spike portion (11).

8. The cell sap sample processing device according to claim 1, wherein, It further comprises a first pipeline connecting the suction component (3) and the tube body (1), a second pipeline connecting the diversion component (4) and the tube body (1), and a control component for controlling the opening and closing of the first pipeline or the second pipeline.

9. The cell sap sample processing device according to claim 8, characterized in that, The control component comprises solenoid valves respectively installed on the first pipeline and the second pipeline.

10. The cell sap sample processing device according to claim 1, characterized in that, The suction component (3) is an injection pump.