Support layer and biosensor big card thereof
By using a support layer design with a specific shape and distribution in the biosensor card, the problems of low cutting success rate and dry reagent fragmentation are solved, and more efficient production and lower production costs are achieved.
Patent Information
- Application Number
- CN202422129899.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-08-31
- Publication Date
- 2025-07-11
- Estimated Expiration
- 2034-08-31
AI Technical Summary
In the prior art, the cutting success rate of electrochemical biosensors is low during mass production, and the dry film-forming chemical reagent layer is prone to fragmentation, resulting in high production costs and low yield.
A support layer design, including a hollow structure with specific shapes and distributions, is used to create a biosensor card. By adjusting the shape and position of the hollow, it reduces the load capacity during the cutting process, reduces dry reagent fragmentation, and improves the cutting success rate.
It reduces the wear frequency of cutting tools, reduces energy consumption, improves the cutting success rate and yield rate of biosensors, reduces production costs, and reduces the fragmentation ratio of dry reagents.
Smart Images
Figure CN223091886U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the field of electrochemical biosensors, in particular to a support layer and a large card of a biosensor. Background Art
[0002] In the prior art, when mass-producing electrochemical biosensors, it is necessary to first manufacture a large card of the biosensor and then cut it into individual biosensors by means of flat-bed die cutting or hob rolling cutting. In order to obtain a cutting edge sufficient to cut the biosensor, an included angle must exist on the cutting edge of the cutting tool.
[0003] Flat-bed die cutting is to place the large card to be cut on the cutting tool, and the supporting components apply pressure to the large card to be cut. In this way, under the combined action of the supporting components and the cutting tool, the large card to be cut is cut at the position of the cutting edge of the cutting tool. The supporting components stop applying pressure and lift up, and the cut biosensors can be taken out. Experiments have proved that the more layers the biosensor is composed of, the greater the pressure that needs to be applied to the supporting components, and the higher the wear frequency of the cutting tool. Moreover, the success rate of separating the biosensor by one-time cutting is relatively low, and secondary cutting is required. Experiments have proved that when the sensor has a three-layer structure, the success rate is less than 20%.
[0004] Rolling cutting is to cut the large card to be cut into small cards with only a single row, and place the small cards between hobs with cutting edges distributed along a cylindrical helix and parallel to each other. As the hob rotates, the small cards to be cut are cut into individual biosensors while rotating with the hob. Two cutting edges in the hob form a set of cutting edges, which act on the small cards to be cut to complete the cutting of one cutting surface of the biosensor. Since the cross-section of a single cutting edge is angled, and the small cards to be cut contain multiple adjacent biosensors, a lateral extrusion force will be generated between each set of cutting edges during the cutting process. The biosensor is located between two sets of cutting edges, and the extrusion force causes a slight displacement between the layers of the biosensor, and there is a certain probability that the chemically reagent layer that has dried into a film on the biosensor will crack. Experiments have proved that the cracking ratio is close to 19%.
[0005] Improving the cutting success rate of biosensors and reducing the cracking ratio of the chemically reagent layer dried into a film are problems that need to be solved during the production process of biosensors. Summary of the Invention
[0006] In order to solve the above problems, the utility model provides a support layer and a large card of a biosensor.
[0007] A support layer for manufacturing a biosensor, including a first hollow and a second hollow. The relationship between the height h2 of the second hollow, the height h1 of the first hollow, and the thickness d2 of the support layer is h1 = h2 = d2. The relationship between the width b2 of the second hollow, the thickness d2 of the support layer, the width b1 of the first hollow, the cutting edge angle θ of the cutting tool, the effective use width L of the support layer, and the number X of biosensors obtained per row of each support layer is In a specific case, the second hollow is in the shape of or shape.
[0008] In a further case, the support layer further includes a third hollow and a fourth hollow, and the numbers of the first hollow, the second hollow, the third hollow, and the fourth hollow are X, 1, 1, and X - 1 respectively. In particular, the height h3 of the third hollow is equal to the height h4 of the fourth hollow, that is, h1 = h2 = h3 = h4 = d2. The width of the third hollow and b3 < L / X - b1. The width b4 of the fourth hollow is b4 = b2 + b3, and b4 <
[0009] L / X - b1.
[0010] In a further case, the second hollow and the third hollow are symmetrically arranged along the axis. In a specific case, the fourth hollow is in the shape of "Y" or shape.
[0011] In some cases, the relationship between the length a2 of the second hollow of the support layer and the length a1 of the first hollow is a2 ≤ a1. In other cases, the relationship between the length a2 of the second hollow of the support layer and the length a1 of the first hollow is a2 > a1. The length of the second hollow does not simply refer to the length of a specific hollow, but can refer to the lengths of the above-mentioned third hollow and fourth hollow.
[0012] A biosensor card includes a bottom card, a support layer, and a film. An electrode system combination is formed on the bottom card and includes dry reagents whose quantity is proportional to the number of electrode systems in the electrode system combination. One electrode system corresponds to at least one dry reagent that partially overlaps with the electrode system. The above support layer covers the bottom card. The film covers the support layer. The film, the support layer, and the bottom card together form X sample channels per row and at least X hollow areas per row. The hollow areas define the shape of the biosensor.
[0013] In a further case, the number of hollow areas per row is X + 1.
[0014] The beneficial effects of the present utility model include: When using the support layer of the present utility model to produce the bio - sensor card, the punching force required for cutting the bio - sensor card is reduced, which can reduce the replacement frequency of the cutting edge of the cutting tool, reduce energy consumption and lower production costs at the same time; The proportion of dry reagent fragmentation during the cutting process of the bio - sensor card is reduced, so that more finished products meeting quality requirements can be obtained in each batch production, reducing production costs from another aspect; The hollow area provides more possibilities for the final shape of the bio - sensor. Description of the Drawings
[0015] Figure 1 One of the front views of the support layer of the present utility model.
[0016] Figure 2 Partial enlarged front - view of the cutting process of the cutting tool.
[0017] Figure 3 Bio - sensor obtained by manufacturing using the support layer of the present utility model.
[0018] Figure 4 Spatial manufacturing layer in the bio - sensor obtained by manufacturing using the support layer of the present utility model.
[0019] Figure 5 Another front - view of the support layer of the present utility model.
[0020] Figure 6 The third front - view of the support layer of the present utility model.
[0021] Figure 7 Front - view of the spatial manufacturing layer in the bio - sensor obtained by manufacturing using the support layer of the present utility model.
[0022] Figure 8 One of the bio - sensor cards obtained by manufacturing using the support layer of the present utility model.
[0023] Figure 9 Another bio - sensor card obtained by manufacturing using the support layer of the present utility model.
[0024] Figure 10 Exploded view schematic diagram of the bio - sensor card of the present utility model.
[0025] Bio - sensor 1; Substrate layer 11; Electrode system 111; Dry reagent 112; Spatial manufacturing layer 12; Cover plate layer 13; Sample channel 14; Left side of the spatial manufacturing layer 121; Right side of the spatial manufacturing layer 122; Top side of the spatial manufacturing layer 123; Bottom side of the spatial manufacturing layer 124; First hollow 125; Second hollow 126; Third hollow 127; Fourth hollow 128; Bio - sensor card 2; Bottom card 21; Electrode system combination 211; Support layer 22; Coating film 23; Cutting tool 5; Cutting edge 51. Detailed implementation mode
[0026] The biosensor mentioned in the present utility model includes a substrate layer, a space manufacturing layer and a cover plate layer.
[0027] Embodiment 1
[0028] As Figure 1 shown, one of the support layers 22, which is one of the raw materials for manufacturing the biosensor 1, is used to form the space manufacturing layer 12 of the biosensor. During the manufacturing process of the biosensor, a single biosensor is formed by cutting with a cutting tool having a cutting edge 51 with an included angle θ = 25°, as Figure 2 shown. The effective use width of the support layer is L = 9 cm, including a first hollow 125 and a second hollow 126. 4 rows of space manufacturing layers 12 can be formed on each support layer, and X = 10 space manufacturing layers can be formed in each row, for a total of 40 space manufacturing layers. Within the effective use width of the support layer, 10 first hollows 125 and 10 second hollows 126 can be formed in each row. The second hollow is in the shape of shape. Of course, it can also be in the shape of shape, or any other shape. The shape of the second hollow is related to the shape of the biosensor finally manufactured, and the shape of the second hollow limits the final shape of the biosensor. When the second hollow is in the shape of shape, a biosensor with the shape shown in Figure 3 (a) can be manufactured and cut. The single biosensor obtained includes a first sensor width l and a second sensor width l', l' < l, and the second width l' gradually increases from the top edge of the space manufacturing layer to the bottom edge of the space manufacturing layer and transitions into the first width l. The transformation position where the second width l' becomes the first width l can be at any position on the left or right side of the space manufacturing layer and is associated with the shape of the second hollow. Each biosensor includes 1 first hollow 125, 1 second hollow 126, a substrate layer 11, an electrode system 111, a dry reagent 112, a space manufacturing layer 12, a cover plate layer 13, and a sample channel 14.
[0029] As Figure 4As shown, the front view, top view, and left view of the space manufacturing layer in the biosensor obtained by manufacturing using the support layer of the present utility model are presented. The length a1 and width b1 of the first hollow are positively correlated with the amount of liquid sample required for the use of a single biosensor, and can be calculated and designed according to the preset sample addition amount of the sensor. The height h1 of the first hollow is the same as the thickness d2 of the support layer. In this embodiment, a1 = 10 mm, b1 = 1.2 mm, and d2 = 0.17 mm. The width b2 of the second hollow is greater than or equal to the thickness d2 of the support layer divided by cosθ, but less than the effective use width of the support layer divided by the number of space manufacturing layers that can be formed in each row minus the width b1 of the first hollow. The height h2 of the second hollow is the same as the thickness d2 of the support layer, that is, h1 = h2 = d2, Specifically, h1 = h2 = 0.17 mm, That is, 0.8880 cm > b2 ≥ 0.001876 cm. Among them, in the same space manufacturing layer, the width of the second hollow refers to the maximum width of the second hollow, and the second hollow is located on the left side of the space manufacturing layer.
[0030] As Figure 7 (a)(c) shown, for the space manufacturing layer in the biosensor obtained by manufacturing using the support layer of the present utility model, the first hollow is located on the right side of the space manufacturing layer, and the second hollow is located on the left side of the space manufacturing layer. The positions of the first hollow and the second hollow can be interchanged.
[0031] Embodiment 2
[0032] As Figure 5 、 Figure 6 shown, a support layer, which is one of the raw materials for manufacturing a biosensor and is used to form the space manufacturing layer of the biosensor. During the manufacturing process of the biosensor, a single biosensor is formed by cutting using a cutting tool with a cutting edge angle θ = 31°. The space manufacturing layer in the single biosensor obtained by cutting is as Figure 7(as shown in (b) and (d)). The effective usable width of the support layer is L = 22.5 cm, including the first hollow, the second hollow, the third hollow 127, and the fourth hollow 128. Each support layer can form 8 rows of space manufacturing layers, and each row can form X = 25 space manufacturing layers. The "..." in the figure is a repeated pattern omitted to avoid making the figure too large. 25 first hollows, 1 second hollow, 1 third hollow, and 24 fourth hollows can be formed on each support layer. The fourth hollow can be divided to form the second hollow and the third hollow. The second hollow, the third hollow, and the fourth hollow help to cut and form individual biosensors during the manufacturing process of the biosensor. During the manufacturing process of the biosensor, after the fourth hollow is divided into the second hollow and the third hollow, individual biosensors are formed. The space manufacturing layer of each biosensor includes 1 first hollow, 1 second hollow, and 1 third hollow. The second hollow and the third hollow are located on the left side and the right side of the space manufacturing layer respectively, and the first hollow is located in the middle of the second hollow and the third hollow, as Figure 7 shown in (b) and (d), the second hollow and the third hollow have different sizes, as Figure 5 and Figure 6 shown, the second hollow and the third hollow have the same size.
[0033] The length a1 and width b1 of the first hollow are positively correlated with the amount of liquid sample required when using an individual biosensor, and can be calculated and designed according to the preset sample loading amount of the sensor. Since the first hollow, the second hollow, the third hollow, and the fourth hollow are all on the support layer and penetrate the support layer, the height h1 of the first hollow, the height h2 of the second hollow, the height h3 of the third hollow, and the height h4 of the fourth hollow are the same as the thickness d2 of the support layer. In this embodiment, a1 = 8 mm, b1 = 1.4 mm, d2 = 0.18 mm. The width b2 of the second hollow and the width b3 of the third hollow are greater than or equal to the thickness d2 of the support layer divided by cosθ, but less than the effective usable width of the support layer divided by the number of space manufacturing layers that can be formed in each row minus the width b1 of the first hollow. The width b4 of the fourth hollow is equal to the sum of the width b2 of the second hollow and the width b3 of the third hollow, and b4 < L / X - b1. The height h2 of the second hollow is the same as the thickness d2 of the support layer, that is, h1 = h2 = d2, and b4 = b2 + b3, and b4 < L / X - b1. Specifically, h1 = h2 = h3 = h4 = 0.18 mm, 22.5 / 25 - 0.014 = 0.8860 cm, That is, 0.8860 cm > b2 ≥ 0.002100 cm, 0.8860 cm > b3 ≥ 0.002100 cm, b4 = b2 + b3, and b4 < 0.8860 cm. Among them, in the same spatial manufacturing layer, the widths of the second hollow, the third hollow, and the fourth hollow refer to the maximum widths of the second hollow.
[0034] Specifically, as Figure 5 , Figure 6 shown, the fourth hollow presents a "Y" shape or shape, and the second hollow and the third hollow are symmetrically arranged with the first hollow as the central axis, that is, the size of the second hollow is equal to the size of the third hollow. Correspondingly, that is, 0.4430 cm > b2 = b3 ≥ 0.002100 cm.
[0035] Such as Figure 3 (b) shown, the bottom edge of the spatial manufacturing layer of a single biosensor manufactured using the support layer in this embodiment has a first width l, and the top edge of the spatial manufacturing layer has a second width l', l' < l, and the second width l' gradually increases from the top edge of the spatial manufacturing layer towards the bottom edge of the spatial manufacturing layer to transition into the first width l. The transformation position where the second width l' becomes the first width l can be located at any position on the left and right sides of the spatial manufacturing layer and is associated with the shapes of the second hollow, the third hollow, and the fourth hollow.
[0036] Example 3
[0037] To complete the manufacturing of a single biosensor, cover the support layer of Example 1 or Example 2 on the bottom card 21 on which the electrode system combination and the dry reagent are formed, and then cover the film 23 on the support layer to form a large biosensor card 2 with tightly combined layers, as Figure 8 and Figure 9 shown, and then cutting the large card can obtain a single biosensor.
[0038] During the process of cutting the large biosensor card, the support layer in Example 1 is cut into the spatial manufacturing layer of a single biosensor, and the spatial manufacturing layer contains 1 first hollow and 1 second hollow. That is to say, in order to form X biosensors in each row of the spatial manufacturing layer, X first hollows and X second hollows need to be formed in each row. One or more rows of spatial manufacturing layers can be formed on the support layer. For the case where the second hollow presents a shape, during the production of biosensors, cutting along the edge of the second hollow can obtain X biosensors in each row.
[0039] Such as Figure 8As shown, a biosensor card formed by manufacturing with the support layer of Example 1, which contains 4 rows * 10 biosensors, i.e., X = 10, includes a base card, a support layer, and a coating film. An electrode system combination containing 4 rows * 10 electrode systems is formed on the base card. The electrode system combination includes 4 rows * 10 dry reagents, and each dry reagent partially overlaps with each electrode system. The base card, the support layer, and the coating film together form 4 rows * 10 sample channels and 4 rows * 10 hollow areas. The shape of the hollow area is the same as that of the second hollow-out, and it is composed of the base card, the support layer, and the coating film together, which is used to improve the cutting success rate when the biosensor card is cut and reduce the proportion of dry reagent fragmentation while defining the shape of the biosensor. Among them, "……" represents the content that is omitted in the figure but is the same as the content already shown in the actual situation.
[0040] During the process of cutting the card, the support layer in Example 2 is cut into a space manufacturing layer for a single biosensor. The space manufacturing layer contains 1 first hollow-out, 1 second hollow-out, and 1 third hollow-out. For each row of the space manufacturing layer on the support layer, starting from the first fourth hollow-out, the fourth hollow-out can be divided into a second hollow-out and a third hollow-out. Specifically, the first fourth hollow-out can be divided into the third hollow-out of the first space manufacturing layer and the second hollow-out of the second space manufacturing layer. The second fourth hollow-out can be divided into the second hollow-out of the third space manufacturing layer and the third hollow-out of the second space manufacturing layer. The third fourth hollow-out can be divided into the second hollow-out of the fourth space manufacturing layer and the third hollow-out of the third space manufacturing layer. The fourth fourth hollow-out can be divided into the second hollow-out of the fifth space manufacturing layer and the third hollow-out of the fourth space manufacturing layer. The fifth fourth hollow-out can be divided into the second hollow-out of the sixth space manufacturing layer and the third hollow-out of the fifth space manufacturing layer. The sixth fourth hollow-out can be divided into the second hollow-out of the seventh space manufacturing layer and the third hollow-out of the sixth space manufacturing layer, ……, the twenty-third fourth hollow-out can be divided into the second hollow-out of the twenty-fourth space manufacturing layer and the third hollow-out of the twenty-third space manufacturing layer. The twenty-fourth fourth hollow-out can be divided into the second hollow-out of the twenty-fifth space manufacturing layer and the third hollow-out of the twenty-fourth space manufacturing layer.
[0041] That is to say, one or more rows of space manufacturing layers can be formed on the support layer. To form X biosensors in each row of space manufacturing layers, X first hollowings, 1 second hollowing, 1 third hollowing, and X - 1 fourth hollowings need to be formed in each row. For the case where the fourth hollowing presents a "Y" shape, during the production of biosensors, the fourth hollowing is divided along the axis of symmetry of the "Y" shape to form the second hollowing and the third hollowing, thereby completing the cutting of the 1st to the Xth biosensors. When the nth fourth hollowing is not cut, the third hollowing of the nth space manufacturing layer and the second hollowing of the (n + 1)th space manufacturing layer are seamlessly connected and axisymmetric. When the nth fourth hollowing is cut, the nth biosensor is formed, and at the same time, the third hollowing of the nth space manufacturing layer and the second hollowing of the (n + 1)th space manufacturing layer are also formed.
[0042] As Figure 9 shown, a biosensor card containing 5 rows * 25 biosensors formed by using the support layer of Example 2 is manufactured, that is, X = 25, including a bottom card, a support layer, and a film. One electrode system combination containing 5 rows * 25 electrode systems is formed on the bottom card. The electrode system combination includes 5 rows * 2 * 25 dry reagents, and every two dry reagents partially overlap with each electrode system. The bottom card, the support layer, and the film together form 5 rows * 25 sample channels and 5 rows * 26 hollow areas. The shape of the hollow area is the same as that of the second hollowing, the third hollowing, and the fourth hollowing, and is composed of the bottom card, the support layer, and the film together, which is used to improve the cutting success rate when the biosensor card is cut and reduce the proportion of dry reagent fragmentation while defining the shape of the biosensor. Among them, "……" represents the content that is omitted in the figure but is the same as the content already shown in the actual situation.
[0043] Due to the limitation of the picture size, as Figure 10 shown, an exploded view of a biosensor is used to represent the exploded view of the biosensor card. The numbers without parentheses in the figure are the corresponding numbers of the components of the biosensor card, and the numbers in parentheses are the corresponding numbers of the components of the biosensor.
[0044] Experimental Example 1
[0045] Take 30 biosensor cards manufactured with traditional support layers and 30 biosensor cards manufactured with the support layer of the present utility model. Each large card can produce 15 biosensors per row, with a total of 8 rows, for a total of 120.
[0046] For the first experimental object, a biosensor card manufactured by the traditional method, after cutting, biosensors with only the first hollowing can be obtained.
[0047] For the second experimental object, a biosensor card manufactured with the support layer of the present utility model, after cutting, the space manufacturing layer can be obtained asFigure 4 The first hollow shown is in a biosensor that is not on the side of the space manufacturing layer, and the length a2 of the second hollow is less than or equal to the length a1 of the first hollow; for the third experimental subject, after cutting, it can be obtained that the space manufacturing layer reference Figure 7 (a) The first hollow shown is in a biosensor on the side of the space manufacturing layer. Different from the figure, the length a2 of the second hollow is less than or equal to the length a1 of the first hollow; for the fourth experimental subject, after cutting, it can be obtained that the space manufacturing layer reference Figure 4 The first hollow shown is in a biosensor that is not on the side of the space manufacturing layer. Different from the figure, the length a2 of the second hollow is greater than the length a1 of the first hollow; for the fifth experimental subject, after cutting, it can be obtained that the space manufacturing layer is as Figure 7 (a) and Figure 7 (c) The first hollow shown is in a biosensor on the side of the space manufacturing layer, and the length a2 of the second hollow is greater than the length a1 of the first hollow; for the sixth experimental subject, after cutting, it can be obtained that the space manufacturing layer is as Figure 7 (d) The biosensor shown, where the length a2 of the second hollow is greater than the length a1 of the first hollow, and the length a3 of the third hollow is less than or equal to the length a1 of the first hollow; for the seventh experimental subject, after cutting, it can be obtained that the space manufacturing layer is as Figure 5 The biosensor shown, where both the length a2 of the second hollow and the length a3 of the third hollow are less than or equal to the length a1 of the first hollow; for the eighth experimental subject, after cutting, it can be obtained that the space manufacturing layer has a biosensor where both the length a2 of the second hollow and the length a3 of the third hollow are greater than the length a1 of the first hollow.
[0048] Use a die-cutting tool to cut the biosensor large card with punching forces of 3 tons, 10 tons, and 15 tons respectively to obtain the biosensors. Count the number of successfully cut and separated biosensors and divide it by the total number of biosensors that can be produced on one biosensor large card, which is 120, to obtain the cutting success rate.
[0049] Table 1 Cutting success rate experimental results of the first experimental subject
[0050]
[0051] Table 2 Success rate experimental results of the second experimental subject
[0052]
[0053] Table 3 Success rate experimental results of the third experimental subject
[0054]
[0055] Table 4 Success rate experimental results of the fourth experimental subject
[0056]
[0057] Experimental Results of the Success Rate of Subject No. 5 in Table 5
[0058]
[0059] Experimental Results of the Success Rate of Subject No. 6 in Table 6
[0060]
[0061] Experimental Results of the Success Rate of Subject No. 7 in Table 7
[0062]
[0063] Experimental Results of the Success Rate of Subject No. 8 in Table 8
[0064]
[0065] The following conclusions can be drawn from the table: 1. For the same punching force, the cutting success rate of the side of the space manufacturing layer without hollowing is less than that of the side of the space manufacturing layer with one hollowing, which is less than that of the side of the space manufacturing layer with two hollows. 2. The longer the length of the hollowing, the higher the cutting success rate. 3. 10 tons of punching force can be used to replace 15 tons of punching force in production to save energy.
[0066] Similar results were obtained by first cutting the large bio - sensor cards into small cards and then cutting the small cards into bio - sensors, which will not be elaborated here.
[0067] Experimental Example 2
[0068] Prepare 30 large bio - sensor cards each, which are the same as those in Experimental Example 1, that is, 30 cards for each of Subject No. 1 to Subject No. 8. Using a die - cutting tool, directly cut the large bio - sensor cards into bio - sensors with a punching force of 15 tons, count the number of bio - sensors with dry reagent fragmentation, and divide it by the total number of bio - sensors that can be produced on one large bio - sensor card, which is 120, to obtain the dry reagent fragmentation ratio.
[0069] Experimental Results of the Dry Reagent Fragmentation Ratio of Each Subject after Cutting in Table 9
[0070]
[0071] The following conclusions can be obtained from the table: 1. The dry reagent fragmentation ratio of the side of the space manufacturing layer without hollowing is higher than that of the side of the space manufacturing layer with one hollowing, which is higher than that of the side of the space manufacturing layer with two hollows. 2. The dry reagent of the side of the space manufacturing layer with two hollows no longer fragments.
[0072] Similar results are obtained by first cutting the large card of the biosensor into small cards and then cutting the small cards into biosensors, which will not be elaborated here.
[0073] In the present utility model, "first", "second", "third", and "fourth" are for the purpose of illustration and are only used to distinguish names, not representing quantity or order. Moreover, the second and the third can be replaced with each other, and the corresponding data calculation formulas and size limitations can also be replaced with each other.
[0074] The above specific embodiments are used to explain the present utility model, rather than limiting the present utility model. Any modifications and changes made to the present utility model within the spirit and scope of the claims of the present utility model fall within the protection scope of the present utility model.
Claims
1. A support layer for manufacturing a biosensor, characterized in that, It includes a first hollow and a second hollow. The relationship between the height h2 of the second hollow, the height h1 of the first hollow, and the thickness d2 of the support layer is h1 = h2 = d2. The relationship between the width b2 of the second hollow, the thickness d2 of the support layer, the width b1 of the first hollow, the cutting edge angle θ of the cutting tool, the effective use width L of the support layer, and the number X of biosensors obtained by manufacturing each row of each support layer is 2. The support layer according to claim 1, characterized in that The second hollow-out is in the shape of , or .
3. The support layer according to claim 1, wherein It further includes a third hollowing and a fourth hollowing, and the numbers of the first hollowing, the second hollowing, the third hollowing and the fourth hollowing are X, 1, 1 and X - 1 respectively.
4. The support layer according to claim 3, characterized in that, The height h3 of the third hollowing is equal to the height h4 of the fourth hollowing, i.e., h1 = h2 = h3 = h4 = d2, and the width of the third hollowing and b3 < L / X - b1, the width b4 of the fourth hollowing is b4 = b2 + b3, and b4 < L / X - b1.
5. The support layer according to claim 4, characterized in that, The second hollow portion and the third hollow portion are axially symmetrically arranged.
6. The support layer according to claim 5, characterized in that, The fourth hollow is in a "Y" shape or shape.
7. A support layer according to claim 1, characterized in that, The relationship between the length a2 of the second hollowing and the length a1 of the first hollowing is a2 ≤ a1.
8. A support layer according to claim 1, characterized in that, The relationship between the length a2 of the second hollowing and the length a1 of the first hollowing is a2 > a1.
9. A biosensor card, comprising a bottom card, a support layer and a coating film, characterized in that, An electrode system combination is formed on the bottom card and includes dry reagents whose quantity is proportional to the number of electrode systems in the electrode system combination. One electrode system corresponds to at least one dry reagent that partially overlaps with the electrode system; a support layer is as described in any one of claims 1 - 8 and covers the bottom card; a film covers the support layer, and the film, the support layer and the bottom card together form X sample channels in each row and at least X hollow areas in each row, and the hollow areas define the shape of the biosensor.
10. A large card of a biosensor according to claim 9, characterized in that, The number of the hollow areas in each row is X + 1.