Granulation device for preparing polymer microspheres with uniform particle size

Abstract

The utility model discloses a granulation device for preparing polymer microspheres with uniform particle size, which relates to the technical field of chemistry, and comprises a granulation kettle and a pulse mechanism, the lower end of the granulation kettle is connected with a nozzle, one end of the nozzle far away from the granulation kettle is clamped with an injection pipe, the inner wall of the injection pipe is provided with a flow sensor, and the flow sensor is connected with the pulse mechanism. The pulse mechanism comprises an air compressor, a connecting pipe, a pulse pipe and a plurality of sprayers, the pulse pipe is installed in the spraying pipe, the air compressor is installed on the spraying pipe, the two ends of the connecting pipe are connected with the air compressor and the pulse pipe respectively, the sprayers are installed on the pulse pipe, and the sprayers are installed at a certain inclination angle; according to the utility model, the nozzle is convenient to disassemble and replace, the nozzle can be replaced according to the granulation requirement, the nozzle can be cleaned regularly through the pulse mechanism, and the problem of nozzle pore channel blockage caused by residual solidification of polymer solution and mixing of impurities is effectively solved.

Description

Technical Field

[0001] The utility model relates to the technical field of chemistry, and specifically relates to a granulating device for preparing polymer microspheres with uniform particle size. Background Art

[0002] In the fields of materials chemical engineering and chemistry, polymer microspheres with uniform particle size have been widely used in many fields such as biomedicine, catalyst carriers, coating additives, and chromatographic separation due to their unique physical and chemical properties. For example, in the field of biomedicine, polymer microspheres with uniform particle size can be used as drug sustained-release carriers to accurately control the drug release rate and dosage; in chromatographic separation, their uniform particle size helps to improve the separation efficiency and accuracy.

[0003] In related technologies, a nozzle is usually used to spray a polymer solution in the form of droplets into a flowing continuous phase, and by means of hydrodynamic action and phase separation principle, the polymer droplets are solidified to form microspheres with uniform particle size. However, if the number of nozzles is insufficient, the production efficiency will be too low; if the number of nozzles is too large, the production device will be too complex, increasing the manufacturing cost and maintenance difficulty; the residual and solidification of the polymer solution inside the nozzle, or the mixing of impurities, will cause blockage of the nozzle channels. Once blockage occurs, it is necessary to manually stop the machine and disassemble the nozzle for cleaning, which not only interrupts production but also may lead to a decline in product quality due to untimely cleaning. Therefore, those skilled in the art have provided a granulating device for preparing polymer microspheres with uniform particle size to solve the problems raised in the above background art. Summary of the Utility Model

[0004] The purpose of the utility model is to provide a granulating device for preparing polymer microspheres with uniform particle size to solve the problems raised in the above background art.

[0005] To achieve the above purpose, the utility model provides the following technical solutions:

[0006] A granulating device for preparing polymer microspheres with uniform particle size, comprising:

[0007] A granulating kettle, the lower end of the granulating kettle is connected with a nozzle, the end of the nozzle far away from the granulating kettle is clamped with an injection pipe, a first control valve is installed on the injection pipe, and a flow sensor is installed on the inner wall of the injection pipe;

[0008] A pulse mechanism, the pulse mechanism includes an air compressor, a connecting pipe, a pulse pipe and a plurality of nozzles, the pulse pipe is installed in the injection pipe, the air compressor is installed on the injection pipe, the two ends of the connecting pipe are respectively connected with the air compressor and the pulse pipe, an electric control valve is installed on the connecting pipe, and a plurality of nozzles are installed on the pulse pipe and are installed at a certain inclination angle.

[0009] Preferably, a dispersed phase access pipe and a continuous phase discharge pipe are respectively connected to the lower end of the granulation kettle, and second control valves are installed on both the dispersed phase access pipe and the continuous phase discharge pipe.

[0010] Preferably, a polymer microsphere discharge pipe and a continuous phase access pipe are respectively connected to the upper end of the granulation kettle, and third control valves are installed on both the polymer microsphere discharge pipe and the continuous phase access pipe.

[0011] Preferably, a plurality of spray holes are formed in the nozzle, and the inner cavity of the nozzle is filled with particulate matter.

[0012] Preferably, a connection groove is formed at the lower end of the granulation kettle, a sealing gasket is arranged in the connection groove, the nozzle is in contact connection with the sealing gasket, and the nozzle is threadedly connected in the connection groove.

[0013] Preferably, a sealing groove is formed in the nozzle, a sealing ring is arranged in the sealing groove, one end of the injection pipe is clamped in the sealing groove, and one end of the injection pipe is in contact connection with the sealing ring.

[0014] Preferably, connecting pieces are fixedly arranged on both sides of the nozzle, connecting plates are fixedly arranged on both sides of the injection pipe, a rotating handle is rotatably connected between the connecting plates, a buckle ring is rotatably connected to the rotating handle, and the buckle ring is clamped with the connecting piece.

[0015] Compared with the prior art, the beneficial effects of the present utility model are as follows:

[0016] 1. The present utility model facilitates the disassembly and replacement of the nozzle, and the nozzle can be replaced according to the granulation requirements. While ensuring the production efficiency, it avoids the increase in manufacturing cost and maintenance cost caused by the complex device, realizes the flexible control of the production scale, and significantly improves the economic benefit.

[0017] 2. The present utility model can regularly clean the nozzle through the pulse mechanism. The nozzle is installed at a certain inclination angle, so that the compressed air can form a spiral airflow when spraying, effectively covering all corners of the nozzle spray holes and the inner wall of the injection pipe, solving the problem of blockage of the nozzle hole caused by the residual curing of the polymer solution and the mixing of impurities, without the need for frequent manual shutdown for disassembly and cleaning, greatly reducing the number of production interruptions, ensuring the continuity of the production process, and fundamentally eliminating the product quality fluctuations caused by untimely cleaning, ensuring the stable and reliable particle size uniformity of the product. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 is a schematic structural diagram of a granulation device for preparing polymer microspheres with uniform particle size in an embodiment of the present application;

[0019] Figure 2 is Figure 1 the enlarged view at A in

[0020] Figure 3 This is a schematic cross-sectional view of a granulation device for preparing polymer microspheres with uniform particle size in an embodiment of the present application;

[0021] Figure 4 It is Figure 3 the enlarged view at position B in

[0022] Figure 5 It is Figure 4 the enlarged view at position C in

[0023] In the figure: 1. Granulation kettle; 2. Nozzle; 3. Injection pipe; 4. First control valve; 5. Flow sensor; 6. Air compressor; 7. Connecting pipe; 8. Pulse pipe; 9. Sprinkler head; 10. Electric control valve; 11. Dispersed phase access pipe; 12. Continuous phase discharge pipe; 13. Second control valve; 14. Polymer microsphere discharge pipe; 15. Continuous phase access pipe; 16. Third control valve; 17. Spray hole; 18. Particulate matter; 19. Connecting groove; 20. Sealing gasket; 21. Sealing groove; 22. Sealing ring; 23. Connector; 24. Connection plate; 25. Rotating handle; 26. Snap ring. Detailed implementation manners

[0024] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0025] Please refer to Figures 1-5 , the present invention provides a technical solution:

[0026] A granulation device for preparing polymer microspheres with uniform particle size, comprising:

[0027] A granulation kettle 1, the lower end of the granulation kettle 1 is respectively connected with a dispersed phase access pipe 11 and a continuous phase discharge pipe 12, and second control valves 13 are installed on both the dispersed phase access pipe 11 and the continuous phase discharge pipe 12. The upper end of the granulation kettle 1 is respectively connected with a polymer microsphere discharge pipe 14 and a continuous phase access pipe 15, and third control valves 16 are installed on both the polymer microsphere discharge pipe 14 and the continuous phase access pipe 15;

[0028] Inject the continuous phase liquid into the granulation kettle 1 through the continuous phase access pipe 15. After the liquid reaches the appropriate liquid level, close the third control valve 16. At the same time, convey the polymer solution to the nozzle 2 through the injection pipe 3 and wait for spraying.

[0029] The lower end of the granulation kettle 1 is connected with a nozzle 2, and a plurality of spray holes 17 are provided on the nozzle 2. The inner cavity of the nozzle 2 is filled with particles 18, and the particles 18 can be glass beads. The lower end of the granulation kettle 1 is provided with a connecting groove 19, and a sealing gasket 20 is provided in the connecting groove 19. The nozzle 2 is in contact with the sealing gasket 20 and is threadedly connected in the connecting groove 19.

[0030] When the nozzle 2 is connected to the granulating kettle 1, one end of the nozzle 2 is threadedly connected in the connecting groove 19, and the nozzle 2 is in contact with the sealing gasket 20, which can improve the sealing performance of the connection.

[0031] An injection pipe 3 is engaged with one end of the nozzle 2 away from the granulation kettle 1, connecting pieces 23 are fixedly provided on both sides of the nozzle 2, connecting plates 24 are fixedly provided on both sides of the injection pipe 3, a rotating handle 25 is rotatably connected between the connecting plates 24, a buckle 26 is rotatably connected to the rotating handle 25, and the buckle 26 is engaged with the connecting piece 23, a sealing groove 21 is provided on the nozzle 2, a sealing ring 22 is provided in the sealing groove 21, one end of the injection pipe 3 is engaged in the sealing groove 21, and one end of the injection pipe 3 is in contact with the sealing ring 22, a first control valve 4 is installed on the injection pipe 3, and a flow sensor 5 is installed on the inner wall of the injection pipe 3;

[0032] When the nozzle 2 is connected to the injection pipe 3, the injection pipe 3 is engaged in the sealing groove 21, and the injection pipe 3 is in contact with the sealing ring 22. Then, one end of the buckle 26 is engaged with the connecting piece 23. Since one end of the rotating handle 25 is rotatably connected between the connecting plates 24, one end of the rotating handle 25 is turned to engage the buckle 26 with the connecting piece 23.

[0033] When the nozzle 2 and the injection pipe 3 are disassembled, one end of the handle 25 is turned, and then the buckle ring 26 is separated from the connecting piece 23, and the injection pipe 3 is taken out from the sealing groove 21.

[0034] The pulse mechanism includes an air compressor 6, a connecting pipe 7, a pulse tube 8 and a plurality of nozzles 9. The pulse tube 8 is installed in the injection pipe 3. The air compressor 6 is installed on the injection pipe 3. Both ends of the connecting pipe 7 are respectively connected to the air compressor 6 and the pulse tube 8. An electric control valve 10 is installed on the connecting pipe 7. A plurality of nozzles 9 are installed on the pulse tube 8, and the plurality of nozzles 9 are installed at a certain inclination angle.

[0035] During pulsing, when the flow sensor 5 detects abnormal flow in the injection pipe 3 (flow fluctuation exceeding ±5%), or when the preset cleaning time interval (once every 2 hours) is reached, the flow sensor 5 transmits the detected data to the controller, and the controller activates the pulse mechanism; the controller controls the solenoid valve 10 to open, and the air compressor 6 (output pressure range 0.5 - 0.8 MPa) conveys compressed air to the pulse pipe 8 through the connecting pipe 7. The compressed air is ejected from the spray head 9 inclinedly installed on the pulse pipe 8, and the speed of the compressed air ejected from the spray head 9 can reach 30 - 50 m / s, forming a spiral airflow to clean the inner wall of the nozzle 2 and the injection pipe 3, removing the residual polymer solution and impurities. After the cleaning is completed, the solenoid valve 10 is closed, and the air compressor 6 stops working.

[0036] During granulation, the first control valve 4 is opened, and under the action of pressure, the polymer solution is sprayed in the form of droplets through the spray holes 17 on the nozzle 2 into the continuous phase in the granulation kettle 1. At this time, the second control valve 13 on the dispersed phase access pipe 11 and the continuous phase discharge pipe 12 is opened to keep the continuous phase flowing in the granulation kettle 1. With the help of the hydrodynamic action and the phase separation principle, the polymer droplets gradually solidify in the continuous phase to form polymer microspheres with uniform particle size. When a certain amount of polymer microspheres is reached in the granulation kettle 1, the third control valve 16 on the polymer microsphere discharge pipe 14 is opened to discharge and collect the finished microspheres.

[0037] In the above embodiment, a controller is provided on the granulation kettle 1, and the controller is electrically connected to the flow sensor 5, the first control valve 4, the second control valve 13, the third control valve 16, the air compressor 6, and the solenoid valve 10 respectively;

[0038] Meanwhile, the device is provided with multiple safety protections: the injection pipe 3 and the connecting pipe 7 are made of pressure-resistant and explosion-proof materials and can withstand a pressure of more than 1.2 MPa; overload protection and leakage protection devices are provided for the controller, the flow sensor 5, the first control valve 4, the second control valve 13, the third control valve 16, the air compressor 6, and the solenoid valve 10; a heat-insulating and anti-scalding layer is provided on the outer surface of the granulation kettle 1 to avoid accidental scalding of the operator.

[0039] Although the embodiments of the present invention have been shown and described, it will be understood by those of ordinary skill in the art that various changes, modifications, substitutions, and variations can be made to these embodiments without departing from the principles and spirit of the present invention, and the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A granulation device for preparing polymer microspheres with uniform particle size, characterized in that, Including: A granulation kettle (1), the lower end of the granulation kettle (1) is connected to a nozzle (2), one end of the nozzle (2) away from the granulation kettle (1) is clamped with an injection pipe (3), a first control valve (4) is installed on the injection pipe (3), and a flow sensor (5) is installed on the inner wall of the injection pipe (3); A pulse mechanism, the pulse mechanism includes an air compressor (6), a connecting pipe (7), a pulse pipe (8) and a plurality of spray heads (9), the pulse pipe (8) is installed in the injection pipe (3), the air compressor (6) is installed on the injection pipe (3), the connecting pipe (7) is connected to the air compressor (6) and the pulse pipe (8) at both ends respectively, an electric control valve (10) is installed on the connecting pipe (7), a plurality of the spray heads (9) are installed on the pulse pipe (8), and a plurality of the spray heads (9) are installed at a certain inclination angle.

2. The granulation device for preparing polymer microspheres with uniform particle size according to claim 1, characterized in that: The lower end of the granulation kettle (1) is respectively connected with a dispersed phase access pipe (11) and a continuous phase discharge pipe (12), and second control valves (13) are installed on both the dispersed phase access pipe (11) and the continuous phase discharge pipe (12).

3. A granulation device for preparing polymer microspheres with uniform particle size according to claim 1, characterized in that: The upper end of the granulation kettle (1) is respectively connected with a polymer microsphere discharge pipe (14) and a continuous phase access pipe (15), and third control valves (16) are installed on both the polymer microsphere discharge pipe (14) and the continuous phase access pipe (15).

4. The granulation device for preparing polymer microspheres with uniform particle size according to claim 1, characterized in that: A plurality of spray holes (17) are formed in the nozzle (2), and the inner cavity of the nozzle (2) is filled with particulate matter (18).

5. The granulation device for preparing polymer microspheres with uniform particle size according to claim 1, characterized in that: A connection groove (19) is formed at the lower end of the granulation kettle (1), a sealing gasket (20) is arranged in the connection groove (19), the nozzle (2) is in contact connection with the sealing gasket (20), and the nozzle (2) is threadedly connected in the connection groove (19).

6. The granulation device for preparing polymer microspheres with uniform particle size according to claim 1, characterized in that: A sealing groove (21) is formed in the nozzle (2), a sealing ring (22) is arranged in the sealing groove (21), one end of the injection pipe (3) is clamped in the sealing groove (21), and one end of the injection pipe (3) is in contact connection with the sealing ring (22).

7. A granulation device for preparing polymer microspheres with uniform particle size according to claim 1, characterized in that: Connectors (23) are fixedly arranged on both sides of the nozzle (2), connecting plates (24) are fixedly arranged on both sides of the injection pipe (3), a rotating handle (25) is rotatably connected between the connecting plates (24), a buckle ring (26) is rotatably connected to the rotating handle (25), and the buckle ring (26) is clamped with the connectors (23).

Images