Constant-temperature free nucleic acid DNA preservation equipment

Abstract

The utility model relates to the technical field of biotechnology, in particular to constant-temperature free nucleic acid DNA (deoxyribonucleic acid) preservation equipment which comprises a constant-temperature preservation outer shell for preserving free nucleic acid DNA, a base is arranged at the bottom of the constant-temperature preservation outer shell, and a top cover is mounted at the top of the constant-temperature preservation outer shell. According to the utility model, the base arranged at the bottom of the constant-temperature preservation outer shell is used for providing support for internal parts; due to the fact that the storage grooves which are evenly arranged at equal intervals are formed in the top of the constant-temperature storage outer shell, the free nucleic acid DNA can be stored in order; the heat conduction pipes are arranged in each group of storage grooves, so that heat can be effectively transferred, and the temperature condition required for storing the free nucleic acid DNA is ensured; a water bath heat preservation area arranged in the constant-temperature preservation outer shell provides a uniform and stable temperature environment for free nucleic acid DNA; the constant-temperature heating rods are symmetrically arranged on the two sides of the bottom in the constant-temperature storage outer shell and can control the temperature; and the motor and the stirring blades are embedded in the center of the top surface of the base, so that the internal water temperature is more uniform.

Description

Technical Field

[0001] The utility model relates to the technical field of biotechnology, in particular to a constant temperature type free nucleic acid DNA storage device. Background Art

[0002] With the rapid advancement of biomedical research and clinical diagnostic technologies, cell-free DNA (cfDNA) (such as cfDNA in plasma) is an important biomarker, and its preservation and stability have become critical factors affecting the accuracy and reliability of experimental results. Traditional cell-free DNA storage tubes often face challenges such as temperature fluctuations, sample degradation, and enzymatic contamination during storage, making them difficult to meet the requirements of long-term, high-quality storage. Therefore, it is particularly important to develop new cell-free DNA storage devices that can effectively maintain a constant temperature, inhibit sample degradation, and reduce external interference. Existing cell-free DNA storage devices have shortcomings in temperature control and are often unable to maintain a constant storage temperature for long periods of time. Temperature fluctuations can cause changes in the chemical reaction rates of DNA molecules, accelerate DNA degradation, and affect sample integrity and stability. Utility Model Content

[0003] The purpose of the present invention is to provide a constant temperature type free nucleic acid DNA storage device to solve the problem raised in the above background technology that the existing free nucleic acid DNA storage device cannot maintain a constant storage temperature for a long time.

[0004] To achieve the above objectives, the present invention provides the following technical solutions:

[0005] A constant temperature type cell-free nucleic acid DNA storage device, comprising a constant temperature storage outer shell for storing free nucleic acid DNA, wherein the bottom of the constant temperature storage outer shell is provided with a base, and the top of the constant temperature storage outer shell is provided with a top cover;

[0006] The constant temperature storage outer shell is a hollow structure with a plurality of storage slots arranged evenly and equidistantly on the top. A heat pipe for storing free nucleic acid DNA is installed in each group of the storage slots. The constant temperature storage outer shell has a built-in water bath insulation area, and constant temperature heating rods are symmetrically arranged on both sides of the bottom of the constant temperature storage outer shell.

[0007] A motor is embedded in the center of the top surface of the base, and an output shaft of the motor passes through the bottom of the constant temperature preservation outer shell and extends to the inside. A stirring blade is connected to the output shaft of the motor.

[0008] Preferably, a temperature display screen for displaying the internal water bath temperature is installed on the outer wall of the constant temperature preservation outer shell.

[0009] Preferably, two groups of tube sockets for fixing constant temperature heating rods are installed on the inner side wall of the constant temperature preservation shell.

[0010] Preferably, the outer walls of the constant temperature storage shell and the top cover are both provided with a heat insulation layer.

[0011] Preferably, the insulation layer is made of medical-grade rubber-plastic insulation board with a thickness of 3-7 mm.

[0012] Preferably, a battery is installed in the base to provide electrical energy for the constant temperature heating rod and the motor.

[0013] Preferably, the top cover is sleeved and matched with the top of the constant temperature preservation outer shell, and the bottom surface of the top cover is installed with sealing plugs with the same number and size as the storage slots and plug-fitting.

[0014] Compared with the existing technology, the beneficial effects of the present invention are:

[0015] In this constant-temperature cell-free DNA storage device, a base arranged at the bottom of the constant-temperature storage outer shell provides support for the internal components; due to the multiple storage slots opened on the top of the constant-temperature storage outer shell and arranged evenly and equidistantly, the free nucleic acid DNA can be stored in an orderly manner; the heat pipes installed in each group of storage slots can effectively transfer heat to ensure the temperature conditions required for the storage of free nucleic acid DNA; the water bath insulation area built into the constant-temperature storage outer shell provides a uniform and stable temperature environment for the free nucleic acid DNA; constant-temperature heating rods symmetrically arranged on both sides of the bottom of the constant-temperature storage outer shell can control the temperature; the motor embedded in the center of the top surface of the base and the stirring blade connected to its output shaft make the internal water temperature more uniform, thereby ensuring temperature consistency and improving the effect and quality of free nucleic acid DNA storage.

[0016] In this constant temperature type free nucleic acid DNA storage device, a temperature display screen for displaying the internal water bath temperature is installed on the outer wall of the constant temperature storage shell. Through the set temperature display screen, the user can understand the temperature of the water bath inside the constant temperature storage shell in real time and intuitively, so as to accurately control the temperature conditions of the storage environment.

[0017] This constant-temperature cell-free DNA storage device features an insulation layer that enhances the thermal insulation performance of the outer shell and top cover, reducing heat loss and helping to maintain a stable internal temperature. The insulation layer utilizes medical-grade rubber-plastic insulation board, further enhancing thermal insulation and providing more favorable conditions for the storage of cell-free DNA. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] The accompanying drawings are used to provide a further understanding of the present invention and constitute a part of the specification. Together with the embodiments of the present invention, they provide further detailed explanations, but do not constitute a limitation to the present invention.

[0019] Figure 1 This is a schematic diagram of the exploded structure of the utility model;

[0020] Figure 2 It is a schematic diagram of the cross-sectional structure of the utility model;

[0021] Figure 3 It is a structural diagram of the present utility model.

[0022] The meaning of the symbols in the figure:

[0023] 10. Constant temperature storage shell; 11. Storage tank; 12. Temperature display screen; 13. Tube socket; 14. Constant temperature heating rod; 15. Insulation layer;

[0024] 20. Base; 21. Motor; 22. Stirring blade; 23. Battery;

[0025] 30. Top cover; 31. Sealing plug;

[0026] 40. Heat pipe. DETAILED DESCRIPTION

[0027] The following will be combined with the embodiments of the present invention and the accompanying drawings to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0028] In the description of the present invention, it should be understood that the terms "center", "vertical", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise" and the like to indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0029] Constant temperature free nucleic acid DNA storage equipment, such as Figure 1-Figure 3As shown, it includes a constant temperature storage shell 10 for storing free nucleic acid DNA, a base 20 is provided at the bottom of the constant temperature storage shell 10, and a top cover 30 is installed on the top of the constant temperature storage shell 10; the constant temperature storage shell 10 is a hollow structure and has a plurality of storage slots 11 arranged evenly and equidistantly on the top, each group of storage slots 11 is installed with a heat pipe 40 for holding free nucleic acid DNA, the constant temperature storage shell 10 has a built-in water bath insulation area, and constant temperature heating rods 14 are symmetrically provided on both sides of the bottom of the constant temperature storage shell 10; a motor 21 is embedded in the center of the top surface of the base 20, and the output shaft of the motor 21 passes through the bottom of the constant temperature storage shell 10 and extends to the interior, and a stirring blade 22 is connected to the output shaft of the motor 21. The constant temperature storage shell 10 is provided with a stable space for the storage of free nucleic acid DNA. The base 20 provided at the bottom of the constant temperature storage shell 10 provides support for the internal components. Due to the several storage grooves 11 arranged evenly and equidistantly on the top of the constant temperature preservation outer shell 10, the free nucleic acid DNA can be stored in an orderly manner. The heat pipes 40 installed in each group of storage grooves 11 can effectively transfer heat to ensure the temperature conditions required for the preservation of free nucleic acid DNA. The water bath insulation area built into the constant temperature preservation outer shell 10 provides a uniform and stable temperature environment for the free nucleic acid DNA. The constant temperature heating rods 14 symmetrically arranged on both sides of the bottom of the constant temperature preservation outer shell 10 can control the temperature. The motor 21 embedded in the center of the top surface of the base 20 and the stirring blade 22 connected to its output shaft make the internal water temperature more uniform, thereby ensuring the temperature consistency and improving the effect and quality of the preservation of free nucleic acid DNA.

[0030] Furthermore, a temperature display screen 12 for displaying the internal water bath temperature is installed on the outer wall of the constant temperature preservation outer shell 10. Through the set temperature display screen 12, the user can understand the temperature of the water bath inside the constant temperature preservation outer shell 10 in real time and intuitively, so as to accurately control the temperature conditions of the preservation environment.

[0031] Specifically, two sets of tube sockets 13 for fixing the constant temperature heating rods 14 are installed on the inner wall of the constant temperature preservation outer shell 10. Through the provision of the tube sockets 13, the installation of the constant temperature heating rods 14 on the inner wall of the constant temperature preservation outer shell 10 is more stable, ensuring the stable operation of the heating rods.

[0032] The outer walls of the constant temperature storage housing 10 and the top cover 30 are both provided with an insulation layer 15. This insulation layer 15 is constructed of medical-grade rubber-plastic insulation board with a thickness of 3-7 mm. This insulation layer 15 enhances the thermal insulation performance of the constant temperature storage housing 10 and the top cover 30, reduces heat loss, and helps maintain a stable internal temperature. This insulation layer 15, constructed of medical-grade rubber-plastic insulation board with a thickness of 3-7 mm, further improves the thermal insulation effect and provides more favorable conditions for the storage of free nucleic acid DNA.

[0033] It is worth noting that a battery 23 is installed in the base 20 to provide electrical energy for the constant temperature heating rod 14 and the motor 21. Through the provision of the battery 23, the constant temperature heating rod 14 and the motor 21 can work normally even without an external power supply, thereby ensuring the flexibility and convenience of the equipment.

[0034] In addition, the top cover 30 is fitted with the top of the constant temperature storage outer shell 10, and the bottom surface of the top cover 30 is equipped with sealing plugs 31 with the same number, matching size and plug-fitting as the storage slots 11. By fitting the top cover 30 with the constant temperature storage outer shell 10 and the sealing plugs 31 on the bottom surface of the top cover 30, the sealing performance of the constant temperature storage outer shell 10 is significantly improved, effectively preventing external factors from interfering with and damaging the free nucleic acid DNA stored inside.

[0035] The working principle of this constant temperature type free nucleic acid DNA preservation device: First, prepare the free nucleic acid DNA sample that needs to be preserved. Put the sample into the heat pipe 40, and the heat pipe 40 is located in the storage groove 11 opened at the top of the constant temperature preservation outer shell 10. Start the constant temperature heating rod 14 to heat the water bath insulation area in the constant temperature preservation outer shell 10 to provide a suitable temperature environment. At the same time, the motor 21 embedded in the center of the top surface of the base 20 starts to work, and its output shaft drives the stirring blade 22 to rotate, so that the internal water temperature is more uniform. Finally, cover the top cover 30 to complete the preservation operation of the free nucleic acid DNA. During the entire preservation process, the constant temperature preservation outer shell 10 provides a stable space for the preservation of free nucleic acid DNA, and the base 20 provides support for the internal components, ensuring the effect and quality of the preservation of free nucleic acid DNA.

[0036] The above shows and describes the basic principles, main features, and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The above embodiments and descriptions are merely preferred examples of the present invention and are not intended to limit the present invention. Various changes and improvements may be made to the present invention without departing from the spirit and scope of the present invention, and such changes and improvements fall within the scope of the present invention. The scope of protection claimed in the present invention is defined by the appended claims and their equivalents.

Claims

1. A constant temperature type free nucleic acid DNA storage device, comprising a constant temperature storage outer shell (10) for storing free nucleic acid DNA, characterized in that: The bottom of the constant temperature storage outer shell (10) is provided with a base (20), and the top of the constant temperature storage outer shell (10) is installed with a top cover (30); The constant temperature storage outer shell (10) is a hollow structure and has a plurality of storage slots (11) arranged evenly and equidistantly on the top. A heat pipe (40) for storing free nucleic acid DNA is installed in each group of the storage slots (11). The constant temperature storage outer shell (10) has a built-in water bath insulation area. Constant temperature heating rods (14) are symmetrically arranged on both sides of the bottom of the constant temperature storage outer shell (10). A motor (21) is embedded in the center of the top surface of the base (20), and the output shaft of the motor (21) passes through the bottom of the constant temperature preservation outer shell (10) and extends to the interior. The output shaft of the motor (21) is connected to a stirring blade (22).

2. The constant temperature type free nucleic acid DNA storage device according to claim 1, characterized in that: A temperature display screen (12) for displaying the internal water bath temperature is installed on the outer wall of the constant temperature preservation outer shell (10).

3. The constant temperature type free nucleic acid DNA storage device according to claim 1, characterized in that: Two sets of tube seats (13) for fixing constant temperature heating rods (14) are installed on the inner side wall of the constant temperature preservation outer shell (10).

4. The constant temperature type free nucleic acid DNA storage device according to claim 1, characterized in that: The outer walls of the constant temperature preservation outer shell (10) and the top cover (30) are both provided with a heat insulation layer (15).

5. The constant temperature type free nucleic acid DNA storage device according to claim 4, characterized in that: The insulation layer (15) is made of medical-grade rubber-plastic insulation board with a thickness of 3-7 mm.

6. The constant temperature type free nucleic acid DNA storage device according to claim 1, characterized in that: A battery (23) for providing electrical energy to the constant temperature heating rod (14) and the motor (21) is installed in the base (20).

7. The constant temperature type free nucleic acid DNA storage device according to claim 1, characterized in that: The top cover (30) is sleeve-fitted with the top of the constant temperature storage outer shell (10), and the bottom surface of the top cover (30) is provided with sealing plugs (31) of the same number and size as the storage slots (11) and plug-fitted therewith.

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