Stem cell filtering separator
Through the design of the guide tube and annular electric guide rail, the problem of stem cells accumulation on the secondary filter is solved, efficient separation of stem cell filtration is achieved, filtration efficiency is improved, and filtering is facilitated.
Patent Information
- Application Number
- CN202422192529.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-06
- Publication Date
- 2025-08-22
- Estimated Expiration
- 2034-09-06
AI Technical Summary
After the existing stem cell filtration separator, stem cells are prone to local accumulation on the secondary filter, resulting in insufficiency of filtration.
The design of a guide tube and annular electric guide rail are used to match the fixing disk. The stem cells are evenly guided to the second filter through the guide tube, and the installation and disassembly of the filter is facilitated by connecting the bolts and the fixing ring, and the filtration efficiency is improved in combination with the vibrating motor.
Effectively prevent stem cells from locally stacking on the second filter, increase the filter surface, improve filtration efficiency, and facilitate filter replacement and maintenance.
Smart Images

Figure CN223255243U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to a filter separator, in particular to a stem cell filter separator, and belongs to the technical field of stem cell filter separation. Background Art
[0002] Stem cells are a type of cell with unlimited or immortal self-renewal capacity, capable of producing at least one type of highly differentiated daughter cells. Generally speaking, between stem cells and their terminally differentiated daughter cells lies an intermediate population of progenitor cells known as "committed progenitor cells," which have limited proliferation capacity and restricted differentiation potential. The function of these cell populations is to increase the number of differentiated cells produced after each stem cell division. Stem cells have the ability to self-renew, but their division is actually relatively asymmetric.
[0003] A Chinese patent application (CN201920072089.0) discloses a mesenchymal stem cell filter separator. The first filter can remove larger tissues, while the second filter can effectively separate mesenchymal stem cells. The filter adopts an inverted conical structure to increase the contact area between the tissue and the filter, improving filtration efficiency. However, existing stem cell filter separators, when in use, directly contact the secondary filter after primary filtration. This limited the usable surface area of the secondary filter, causing stem cells to accumulate in one place, resulting in low filtration efficiency.
[0004] In order to solve the above technical problems, a stem cell filtration separator is proposed. Utility Model Content
[0005] In view of this, the present invention provides a stem cell filtration separator to solve or alleviate the technical problems existing in the prior art and at least provide a beneficial option.
[0006] The technical solution of the utility model is implemented as follows: a stem cell filtration separator comprises an upper filtration mechanism and a lower filtration mechanism;
[0007] The upper filter mechanism includes an upper filter cartridge and a first filter screen, the first filter screen is arranged on one side of the interior of the upper filter cartridge, a liquid inlet is integrally formed on one side of the upper filter cartridge, a partition is fixedly connected to one side of the interior of the upper filter cartridge, a guide tube is passed through the interior of the partition, a collecting portion is integrally formed on one end of the guide tube, one end of the guide tube is connected to a liquid outlet head, a fixed disk is fixedly connected to one side of the guide tube, an annular electric guide rail is installed on one side of the partition, and the movable end of the annular electric guide rail is fixedly connected to the fixed disk;
[0008] The lower filter mechanism includes a lower filter cartridge and a second filter screen. The lower filter cartridge is threadedly connected to the upper filter cartridge. The second filter screen is arranged on one side of the interior of the lower filter cartridge. A liquid outlet is integrally formed on one side of the lower filter cartridge.
[0009] Further preferably, a first fixing ring is fixedly connected to an inner side of the upper filter cartridge, a first bolt is threadedly connected to an equidistantly distributed side of the first filter screen, one end of the first bolt is threadedly connected to the first fixing ring, and a second fixing ring is fixedly connected to an inner side of the lower filter cartridge, a second bolt is threadedly connected to an equidistantly distributed side of the second filter screen, and one end of the second bolt is threadedly connected to the second fixing ring.
[0010] Further preferably, a guide plate is fixedly connected to one side of the interior of the lower filter cartridge, support rods are fixedly connected to the bottom of the lower filter cartridge at equal intervals, and one end of the support rods is fixedly connected to a base frame.
[0011] Further preferably, a spiral cooling tube is installed inside the liquid inlet.
[0012] Further preferably, a thermal insulation interlayer is fixedly connected to the interior of the upper filter cartridge and the lower filter cartridge, a sealing ring is fixedly connected to one side of the lower filter cartridge, and one side of the upper filter cartridge is engaged with the sealing ring.
[0013] Further preferably, vibration motors are installed at equal intervals on one side of the first filter screen and the second filter screen.
[0014] The embodiment of the present invention has the following advantages due to the adoption of the above technical solution:
[0015] First, the present invention collects stem cells passing through the first filter screen by providing a guide tube in conjunction with a collection unit. The collected stem cells are then discharged to the second filter screen through the guide tube in conjunction with a liquid outlet head. During the filtration process, the annular electric guide rail drives the fixed disk to rotate, thereby causing the guide tube to continuously rotate, evenly guiding the stem cells to the second filter screen. This prevents localized accumulation of stem cells on the second filter screen, affecting filtration efficiency, and increases the effective filtration surface of the second filter screen.
[0016] 2. The utility model installs and fixes the first filter screen by providing a first fixing ring in conjunction with a first bolt, and installs and fixes the second filter screen by providing a second fixing ring in conjunction with a second bolt, so that the first filter screen and the second filter screen can be removed for replacement or maintenance when necessary.
[0017] The above summary is for the purpose of description only and is not intended to be limiting in any way. In addition to the illustrative aspects, embodiments and features described above, further aspects, embodiments and features of the present invention will be readily apparent by reference to the accompanying drawings and the following detailed description. BRIEF DESCRIPTION OF THE DRAWINGS
[0018] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without any creative work.
[0019] Figure 1 It is a structural diagram of the utility model;
[0020] Figure 2 This is a bottom view of the structure of the utility model;
[0021] Figure 3 This is a cross-sectional structural diagram of the upper filter cartridge of the utility model;
[0022] Figure 4 It is a cross-sectional structural diagram of the middle and lower filter cartridges of the present utility model.
[0023] Figure numerals: 10, upper filtering mechanism; 11, upper filter cartridge; 12, liquid inlet; 13, spiral cooling tube; 14, thermal insulation interlayer; 15, first fixing ring; 16, first filter screen; 17, first bolt; 18, vibration motor; 19, partition; 31, annular electric guide rail; 32, fixing plate; 33, collecting part; 34, guide tube; 35, liquid outlet head; 20, lower filtering mechanism; 21, lower filter cartridge; 22, sealing ring; 23, support rod; 24, base frame; 25, liquid outlet; 26, guide plate; 27, second fixing ring; 28, second filter screen; 29, second bolt. DETAILED DESCRIPTION
[0024] Hereinafter, only certain exemplary embodiments are briefly described. As will be appreciated by those skilled in the art, the described embodiments may be modified in various ways without departing from the spirit or scope of the present invention. Therefore, the drawings and description are to be regarded as illustrative in nature and not restrictive.
[0025] The embodiments of the present invention are described in detail below with reference to the accompanying drawings.
[0026] like Figure 1-4 As shown, an embodiment of the present invention provides a stem cell filtration separator, which is composed of an upper filtration mechanism 10 and a lower filtration mechanism 20 .
[0027] The upper filter mechanism 10 includes an upper filter cartridge 11, a first filter screen 16 and a partition 19. A liquid inlet 12 for liquid inlet is integrally formed on one side of the upper filter cartridge 11. The liquid inlet 12 is hollow inside, and a spiral cooling pipe 13 is installed in the hollow part for cooling the liquid when it is inlet. A first fixing ring 15 is fixedly connected to one side of the upper filter cartridge 11. First bolts 17 are equidistantly threadedly connected to one side of the first filter screen 16. One end of the first bolt 17 is threadedly connected to the first fixing ring 15, which facilitates the installation of the first filter screen 16 on the upper filter cartridge 11. In the upper filter cartridge 11, the partition 19 can be fixed to one side of the interior of the upper filter cartridge 11 by bolts. A guide tube 34 is passed through the interior of the partition 19. A collecting portion 33 is integrally formed at one end of the guide tube 34. One end of the guide tube 34 is connected to a liquid outlet head 35. A fixed disk 32 is fixedly connected to one side of the guide tube 34. An annular electric guide rail 31 is installed on one side of the partition 19. The movable end of the annular electric guide rail 31 is fixedly connected to the fixed disk 32, and the fixed disk 32 and the guide tube 34 are driven to rotate by the annular electric guide rail 31.
[0028] The lower filter mechanism 20 includes a lower filter cartridge 21, a second filter screen 28 and a base frame 24. The lower filter cartridge 21 is threadedly connected to the upper filter cartridge 11, and a sealing ring 22 is fixedly connected to the connection between the lower filter cartridge 21 and the upper filter cartridge 11. The sealing ring 22 is engaged with the upper filter cartridge 11 to enhance the sealing of the connection. A liquid outlet 25 is integrally formed on one side of the lower filter cartridge 21. A second fixing ring 27 is fixedly connected to one side of the lower filter cartridge 21. A second bolt 29 is equidistantly threadedly connected to one side of the second filter screen 28. One end of the second bolt 29 is threadedly connected to the second fixing ring 27. The second filter screen 28 is installed and fixed by the second bolt 29 in cooperation with the second fixing ring 27, which facilitates the disassembly and replacement of the second filter screen 28. A support rod 23 is equidistantly fixedly connected to one side of the base frame 24. One end of the support rod 23 is fixedly connected to the lower filter cartridge 21. The support rod 23 cooperates with the base frame 24 to support the lower filter cartridge 21.
[0029] In one embodiment, in order to prevent the accumulation of dry cells inside the lower filter cartridge 21 from being unable to be discharged, a guide plate 26 is fixedly connected to one side of the interior of the lower filter cartridge 21 .
[0030] In one embodiment, in order to reduce the impact of the external temperature on the interior of the upper filter cartridge 11 and the lower filter cartridge 21 during the filtration process, a thermal insulation interlayer 14 is fixedly connected to the interior of the upper filter cartridge 11 and the lower filter cartridge 21 .
[0031] In one embodiment, in order to improve the filtering efficiency, vibration motors 18 are evenly installed on one side of the first filter screen 16 and the second filter screen 28. The vibration motors 18 drive the first filter screen 16 and the second filter screen 28 to vibrate, thereby improving the filtering efficiency.
[0032] During operation, the present invention is as follows: stem cells are introduced into the upper filter cartridge 11 through the liquid inlet 12, passing through the first filter screen 16, which filters out larger tissues. The stem cells then pass through the collection portion 33 and enter the guide tube 34. The annular electric guide rail 31 drives the fixed disk 32 to rotate, and the fixed disk 32 drives the guide tube 34 to rotate, so that the guide tube 34 cooperates with the liquid outlet head 35 to distribute the stem cells in a ring shape on the second filter screen 28. After being filtered by the second filter screen 28, the stem cells are guided to the liquid outlet 25 through the guide plate 26 for discharge. After filtration, the upper filter cartridge 11 and the lower filter cartridge 21 are separated, the partition 19 is removed, and the first filter screen 16 and the second filter screen 28 are removed for cleaning.
[0033] The above description is merely a specific embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any person skilled in the art can easily conceive of various modifications or substitutions within the technical scope disclosed in the present invention, and such modifications or substitutions are intended to be within the scope of protection of the present invention. Therefore, the scope of protection of the present invention shall be based on the scope of protection of the claims.
Claims
1. A stem cell filtration separator, characterized in that: It comprises an upper filtering mechanism (10) and a lower filtering mechanism (20); The upper filter mechanism (10) comprises an upper filter cartridge (11) and a first filter screen (16), wherein the first filter screen (16) is arranged on one side of the interior of the upper filter cartridge (11), a liquid inlet (12) is integrally formed on one side of the upper filter cartridge (11), a partition (19) is fixedly connected to one side of the interior of the upper filter cartridge (11), a guide tube (34) is passed through the interior of the partition (19), a collecting portion (33) is integrally formed on one end of the guide tube (34), one end of the guide tube (34) is connected to a liquid outlet head (35), one side of the guide tube (34) is fixedly connected to a fixed disk (32), an annular electric guide rail (31) is installed on one side of the partition (19), and a movable end of the annular electric guide rail (31) is fixedly connected to the fixed disk (32); The lower filter mechanism (20) comprises a lower filter cartridge (21) and a second filter screen (28); the lower filter cartridge (21) is threadedly connected to the upper filter cartridge (11); the second filter screen (28) is arranged on one side of the interior of the lower filter cartridge (21); and a liquid outlet (25) is integrally formed on one side of the lower filter cartridge (21).
2. The stem cell filtration separator according to claim 1, characterized in that: A first fixing ring (15) is fixedly connected to one side of the interior of the upper filter cartridge (11); a first bolt (17) is threadedly connected to one side of the first filter screen (16) at equal intervals; one end of the first bolt (17) is threadedly connected to the first fixing ring (15); a second fixing ring (27) is fixedly connected to one side of the interior of the lower filter cartridge (21); a second bolt (29) is threadedly connected to one side of the second filter screen (28) at equal intervals; one end of the second bolt (29) is threadedly connected to the second fixing ring (27).
3. The stem cell filtration separator according to claim 1, characterized in that: A guide plate (26) is fixedly connected to one side of the interior of the lower filter cartridge (21), and support rods (23) are fixedly connected to the bottom of the lower filter cartridge (21) at equal intervals, and one end of the support rod (23) is fixedly connected to a base frame (24).
4. The stem cell filtration separator according to claim 1, characterized in that: A spiral cooling pipe (13) is installed inside the liquid inlet (12).
5. The stem cell filtration separator according to claim 1, characterized in that: The interiors of the upper filter cartridge (11) and the lower filter cartridge (21) are both fixedly connected with a heat-insulating interlayer (14), one side of the lower filter cartridge (21) is fixedly connected with a sealing ring (22), and one side of the upper filter cartridge (11) is engaged with the sealing ring (22).
6. The stem cell filtration separator according to claim 1, characterized in that: Vibration motors (18) are evenly spaced and installed on one side of the first filter screen (16) and the second filter screen (28).
Citation Information
Patent Citations
Mesenchymal stem cell filtering separator
CN209669220U