Mixing device capable of being assembled and separated

By combining the assembled and separated mixing devices to form an integrated mixing device, the problems of low mixing efficiency and material loss of large-volume differential materials are solved, and efficient and low-cost mixing operations are achieved.

CN223299917UActive Publication Date: 2025-09-05WUXI APPTEC INC
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Patent Information

Application Number
CN202421668477.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-07-15
Publication Date
2025-09-05
Estimated Expiration
2034-07-15

AI Technical Summary

Technical Problem

When the existing mixing technology deals with large volume differential materials, the mixing efficiency is low and it is easy to lose during material transfer, making it difficult to meet the quality requirements of the pharmaceutical process.

Method used

A mixing device that can be assembled and separated is designed, and an integrated mixing device is formed by combining multiple mixing devices to avoid the transfer of materials between different mixing devices, and a clamp or bolt and nut structure is used to achieve rapid assembly and disassembly.

Benefits of technology

It significantly improves mixing efficiency, reduces material losses, reduces costs, and adapts to the needs of different mixing processes.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a mixing device capable of being assembled and separated, which comprises a mixing device side wall, a lower sealing part and an upper sealing part, and a sealed mixing operation space is formed by the mixing device side wall, the lower sealing part and the upper sealing part; the lower sealing part comprises a lower sealing part assembly part and a lower sealing part sealing part; the upper sealing part comprises an upper sealing part assembly part and an upper sealing part sealing part. According to the mixing device disclosed by the utility model, a plurality of mixing devices which can be assembled and separated are combined to form an integrated mixing device, so that multi-step mixing operation in a mixing system can be realized, and materials are prevented from being transferred among different mixing devices, thereby obviously reducing material transfer loss. The device has the advantages of being low in cost, easy to assemble and disassemble, high in practicability and wide in application range.
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Description

Technical Field

[0001] The utility model belongs to the technical field of material mixing, in particular to mixing equipment in the pharmaceutical industry, and specifically to a mixing device that can be assembled and separated. Background Art

[0002] In the pharmaceutical industry, mixing is a crucial step in the preparation of solid dosage forms. It not only ensures the uniform distribution of drug ingredients but also has a decisive impact on the quality and efficacy of the final product. Solid dosage forms include, but are not limited to, tablets, capsules, and granules, and mixing is a common process throughout the entire solid dosage form category.

[0003] Mixers are key equipment for achieving uniform mixing of materials and are widely used in mixing materials such as powders or granules. According to different mixing principles, mixers can be divided into mechanical mixers and gravity mixers. Mechanical mixers generate shear force through the rotation of the agitator to promote mixing between materials; while gravity mixers use the weight of the materials themselves and tilting or vibration to achieve mixing. The mixing process can generally be divided into three stages: (1) Convection mixing stage. In this stage, the materials are initially mixed through the movement of small bulk pieces, and the mixing uniformity is rapidly improved. This stage is characterized by a fast mixing speed, but there may be local unevenness problems; (2) Diffusion mixing stage. As the mixing proceeds, the mutual sliding and impact between the material particles begin to play a role, and the mixing speed becomes relatively stable. The mixing effect in this stage is more delicate, which helps to eliminate local unevenness; (3) Balanced mixing stage. Finally, the particle position exchange reaches a dynamic equilibrium state, and the mixing uniformity is kept stable or has only slight fluctuations. In this stage, the operating parameters of the mixer need to be fine-tuned to ensure the mixing quality.

[0004] In actual pharmaceutical manufacturing processes, multi-step mixing is often required to meet specific quality requirements. When the volumes of materials to be mixed in different steps vary significantly, a single mixing tank may not be able to meet the process requirements. Furthermore, material transfer between mixing tanks can result in material loss, impacting mixing efficiency and product quality.

[0005] Although existing mixing technologies can meet the needs of pharmaceutical processes in many cases, they still have limitations in handling the mixing of large and different-volume materials, reducing material loss, and improving mixing efficiency. Therefore, developing new mixing technologies or improving existing mixing equipment is of great significance for improving the preparation efficiency of solid dosage forms and reducing product loss. Utility Model Content

[0006] In view of the above-mentioned defects of the prior art, the utility model provides a mixing device that can be assembled and separated to solve the technical problems of mixing efficiency and mixing loss of materials with large volume differences.

[0007] The specific technical solutions adopted in this utility model are as follows:

[0008] A mixing device that can be assembled and separated includes a mixing device side wall, a lower closing part, and an upper closing part. The mixing device side wall and the lower closing part and the upper closing part form a closed mixing operation space; the lower closing part includes a lower closing part assembly part and a lower closing part closing piece; the upper closing part includes an upper closing part assembly part and an upper closing part closing piece.

[0009] In some specific embodiments, the lower closure assembly and the lower closure closure member are fixed by a lower fastener; and the upper closure assembly and the upper closure closure member are fixed by an upper fastener.

[0010] Furthermore, the lower closing part also includes a lower closing part elastic part, which is located between the lower closing part assembly part and the lower closing part closing part during assembly; the upper closing part also includes an upper closing part elastic part, which is located between the upper closing part assembly part and the upper closing part closing part during assembly.

[0011] In some specific embodiments, a connecting arm is fixed to the side wall of the mixing device for connecting to an external rotating device.

[0012] In some specific embodiments, there are one or more assembleable and separable mixing devices, and a plurality of the assembleable and separable mixing devices are assembled to form an integrated mixing device.

[0013] In some specific embodiments, there are two assembleable and separable mixing devices, namely a secondary mixing device and an upper mixing device. The lower closing part assembly of the upper mixing device and the upper closing part assembly of the secondary mixing device are fixed by the upper fastener of the secondary mixing device.

[0014] Furthermore, the elastic member of the upper closing part of the secondary mixing device is located between the upper closing part assembly part of the secondary mixing device and the lower closing part assembly part of the upper mixing device during assembly.

[0015] In some specific embodiments, the lower closure assembly is configured as a ridge structure, and the lower closure closure is a barrel cover; the upper closure assembly is configured as a ridge structure, and the upper closure closure is a barrel cover.

[0016] Furthermore, holes are relatively provided around the lower closure assembly part and around the lower closure part sealing member, and holes are relatively provided around the upper closure assembly part and around the upper closure part sealing member.

[0017] Furthermore, holes are provided around the elastic part of the lower closing part, and the holes correspond to the holes of the lower closing part assembly part and the lower closing part closing part; holes are provided around the elastic part of the upper closing part, and the holes correspond to the holes of the upper closing part assembly part and the upper closing part closing part.

[0018] In some specific embodiments, the lower fastener and the upper fastener are both clamp structures or bolt and nut structures.

[0019] The assembleable and separable mixing devices are fixed by clamps or bolts and nuts. When the volume of the mixing device needs to be adjusted, the clamps or bolts and nuts can be loosened to disassemble the mixing device. After replacing the mixing device with the required volume, two or more mixing barrels can be assembled and fixed by clamps or bolts and nuts.

[0020] When continuous mixing is required, first pour the material into the secondary mixing unit and secure the lid to the unit with clamps or bolts and nuts to seal it. Once mixing is complete, remove the lid from the secondary unit and secure the lower portion of the upper mixing unit to the upper portion of the secondary mixing unit with clamps or bolts and nuts to form an integrated mixing unit, increasing the mixing volume. This eliminates the need for material transfer and mitigates the risk of material loss during transfer.

[0021] Compared with the prior art, the present invention has the following beneficial effects:

[0022] The mixing device of the utility model combines multiple assembleable and detachable mixing devices to form an integrated mixing device, thereby realizing multi-step mixing operations within a mixing system, avoiding the transfer of materials between different mixing devices, and thus significantly reducing material transfer losses. The device has the characteristics of low cost, easy assembly and disassembly, strong practicality, and a wide range of applications.

[0023] The concept, specific structure and technical effects of the present invention will be further described below in conjunction with the accompanying drawings to fully understand the purpose, characteristics and effects of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 、 Figure 2 They are schematic diagrams of the overall structure of the assembleable and detachable mixing device of the present invention.

[0025] Figure 3 、 Figure 4They are respectively schematic diagrams of the specific implementation process of the present utility model.

[0026] Description of the marks in the figure:

[0027] Figure 1 Middle markings: 1. Secondary upper rib; 2. Secondary connecting arm; 3. Secondary mixing barrel body; 4. Secondary lower rib; 5. Secondary lower barrel cover; 6. Secondary upper barrel cover; 7. Secondary lower clamp; 8. Secondary upper clamp; 9. Superior upper rib; 10. Superior connecting arm; 11. Superior mixing barrel body; 12. Superior lower rib; 13. Superior upper barrel cover; 14. Superior upper clamp.

[0028] Figure 2 Middle markings: 15. Secondary upper perforated rib; 16. Secondary connecting arm; 17. Secondary mixing barrel body; 18. Secondary lower perforated rib; 19. Secondary lower perforated cover plate; 20. Secondary upper perforated cover plate; 21. Secondary upper perforated gasket; 22. Secondary lower perforated gasket; 23. Superior upper perforated rib; 24. Superior mixing barrel body; 25. Superior connecting arm; 26. Superior lower perforated rib; 27. Superior upper perforated cover plate; 28. Superior upper perforated gasket.

[0029] Figure 3 、 Figure 4 Markings: (1) the process of pouring the first step mixing material; (2) the process of closing the secondary mixing barrel for mixing; (3) the process of opening the secondary upper barrel cover; (4) the process of connecting the barrel body of the upper mixing barrel with the barrel body of the secondary mixing barrel; (5) the process of pouring the second step mixing material; (6) the process of closing the upper mixing barrel for mixing. DETAILED DESCRIPTION

[0030] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0031] In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicating directions or positional relationships, are based on the directions or positional relationships shown in the accompanying drawings and are only for the convenience of describing the present invention and simplifying the description. They do not indicate or imply that the devices or components referred to must have a specific direction, be constructed and operate in a specific direction. Therefore, they should not be understood as limiting the present invention. The terms "first", "second", and "third" are used for descriptive purposes only and should not be understood as indicating or implying relative importance. In addition, unless otherwise expressly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense. For example, they can be fixed connections, detachable connections, or integral connections; they can be mechanical connections or electrical connections; they can be direct connections, indirect connections through an intermediate medium, or internal connections between two components. For those skilled in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0032] Example 1

[0033] like Figure 1 As shown, the secondary upper rib 1 is tightly fixed to the upper opening of the secondary mixing barrel body 3, and the secondary lower rib 4 is tightly fixed to the lower opening of the secondary mixing barrel body 3. The secondary upper rib 1, the secondary mixing barrel body 3, and the secondary lower rib 4 form an inverted frustum structure that is internally connected. The secondary connecting arm 2 is fixed to the side of the secondary mixing barrel body 3 for connection to the external rotating shaft. The secondary lower barrel cover 5 has an enclosed area comparable to that of the secondary lower rib 4, and the two can be tightly and seamlessly fitted. The secondary upper barrel cover 6 has an enclosed area comparable to that of the secondary upper rib 1, and the two can be tightly and seamlessly fitted.

[0034] The upper upper rib 9 of the superior is tightly fixed to the upper opening of the upper mixing barrel body 11, and the lower upper rib 12 of the superior is tightly fixed to the lower opening of the upper mixing barrel body 11. The upper upper rib 9 of the superior, the upper mixing barrel body 11, and the lower upper rib 12 of the superior form an inverted frustum structure that is internally connected. The upper connecting arm 10 is fixed to the side of the upper mixing barrel body 11 and is used to connect to the external rotating shaft. The enclosed area of ​​the lower upper rib 12 is comparable to that of the secondary upper rib 1, and the two can be tightly fitted. The upper upper barrel cover 13 of the superior is comparable to that of the upper upper rib 9, and the two can be tightly and seamlessly fitted.

[0035] After the secondary lower barrel cover 5 is fitted to the secondary lower rib 4, a tight and seamless fit is achieved using the secondary lower clamp 7. After the secondary upper barrel cover 6 is fitted to the secondary upper rib 1, a tight and seamless fit is achieved using the secondary upper clamp 8. Alternatively, after the upper lower rib 12 is fitted to the secondary upper rib 1, a tight and seamless fit is achieved using the secondary upper clamp 8. After the upper upper barrel cover 13 is fitted to the upper upper rib 9, a tight and seamless fit is achieved using the upper upper clamp 14.

[0036] (1) The first step is preparation before mixing:

[0037] Before mixing begins, first fit the secondary lower barrel cover 5 onto the secondary lower ridge 4, and then use the secondary lower clamp 7 to tightly secure them to ensure that the material in the middle does not leak out from the bottom.

[0038] (2) First step mixing:

[0039] The required first step mixed material is poured into the secondary mixing barrel body 3. Then, the secondary upper barrel cover 6 is fitted with the secondary upper ridge 1, and then tightly fixed with the secondary upper clamp 8 to form a closed mixing environment.

[0040] The secondary connecting arm 2 is connected to the external rotating shaft, and the mixing barrel is driven to rotate by the rotating shaft to achieve uniform mixing of the materials.

[0041] After the mixing is completed, loosen the secondary upper clamp 8 and remove the secondary upper barrel cover 6 to proceed to the next step.

[0042] (3) Preparation before the second step of mixing:

[0043] The upper lower rib 12 is fitted with the secondary upper rib 1 and then tightly fixed with the secondary upper clamp 8 to ensure that the material does not leak from the junction of the upper lower rib 12 and the secondary upper rib 1 .

[0044] (4) Second step mixing:

[0045] The required second step mixed material is poured into the secondary mixing barrel body 3 and the upper mixing barrel body 11. Next, the upper upper barrel cover 13 is fitted with the upper upper ridge 9, and then the upper upper clamp 14 is used to tightly fix it to form a closed mixing environment.

[0046] The secondary connecting arm 2 or the upper connecting arm 10 is connected to the external rotating shaft, and the mixing barrel is driven to rotate by the rotating shaft to achieve uniform mixing of the materials.

[0047] Example 2

[0048] like Figure 2As shown, the secondary upper perforated rib 15 is tightly fixed to the upper opening of the secondary mixing barrel body 17, and the secondary lower perforated rib 18 is tightly fixed to the lower opening of the secondary mixing barrel body 17. The secondary upper perforated rib 15, the secondary mixing barrel body 17, and the secondary lower perforated rib 18 form an internally through-conical structure. The secondary connecting arm 16 is fixed to the side of the secondary mixing barrel body 17 for connection to the external rotating shaft. The secondary lower perforated cover plate 19, the secondary lower perforated rib 18, and the secondary lower perforated gasket 22 have an equivalent enclosed area and corresponding hole positions, allowing the three to achieve a tight and seamless fit. The secondary upper perforated cover plate 20, the secondary upper perforated rib 15, and the secondary upper perforated gasket have an equivalent enclosed area and corresponding hole positions, allowing the three to achieve a tight and seamless fit.

[0049] The upper upper perforated rib 23 of the upper mixing barrel body 24 is tightly fixed to the upper opening, and the lower upper perforated rib 26 of the upper mixing barrel body 24 is tightly fixed to the lower opening. The upper upper perforated rib 23 of the upper mixing barrel body 24, and the upper lower perforated rib 26 of the upper mixing barrel body form an internally connected inverted frustum structure. The upper connecting arm 25 is fixed to the side of the upper mixing barrel body 24 and is used to connect to the external rotating shaft. The upper lower perforated rib 26 of the upper mixing barrel body 24, the secondary upper perforated rib 15, and the secondary upper perforated gasket 21 have an equivalent enclosed area and corresponding hole positions, allowing them to fit tightly together. The upper upper perforated cover plate 27, the upper upper perforated rib 23, and the upper upper perforated gasket 28 have an equivalent enclosed area and corresponding hole positions, allowing them to fit tightly together.

[0050] After the secondary lower perforated cover plate 19, the secondary lower perforated washer 22, and the secondary lower perforated rib 18 are fitted in sequence according to the corresponding relationship of the holes, a bolt is passed through the hole and a nut is tightened on the other end of the bolt to achieve a tight and seamless fit. After the secondary upper perforated cover plate 20, the secondary upper perforated washer 21, and the secondary upper perforated rib 15 are fitted in sequence according to the corresponding relationship of the holes, a bolt is passed through the hole and a nut is tightened on the other end of the bolt to achieve a tight and seamless fit. Alternatively, after the upper lower perforated rib 26, the secondary upper perforated washer 21, and the secondary upper perforated rib 15 are fitted in sequence according to the corresponding relationship of the holes, a bolt is passed through the hole and a nut is tightened on the other end of the bolt to achieve a tight and seamless fit. After the upper perforated cover plate 27, the upper perforated washer 28 and the upper perforated ridge 23 are tightly fitted in sequence according to the corresponding relationship of the holes, a bolt is passed through the hole and the nut is tightened at the other end of the bolt to achieve a tight and seamless fit.

[0051] (1) The first step is preparation before mixing:

[0052] Before mixing begins, first fit the secondary lower perforated cover plate 19, the secondary lower perforated gasket 22, and the secondary lower perforated ridge 18 tightly together according to the corresponding relationship of the holes, and then use bolts and nuts to tightly fix them to ensure that the middle material will not leak out from the bottom.

[0053] (2) First step mixing:

[0054] Pour the required first step mixed material into the secondary mixing barrel 17. Then, fit the secondary upper perforated cover plate 20, the secondary upper perforated gasket 22, and the secondary upper perforated rib 15 in sequence according to the corresponding relationship of the holes, and then use bolts and nuts to tightly fix them to form a closed mixing environment.

[0055] The secondary connecting arm 16 is connected to the external rotating shaft, and the rotating shaft drives the mixing barrel to rotate to achieve uniform mixing of the materials.

[0056] After the mixing is completed, the bolts and nuts are loosened, and the secondary upper perforated cover plate 20 and the secondary upper perforated gasket 21 are removed for the next step.

[0057] (3) Preparation before the second step of mixing:

[0058] Fit the upper lower perforated rib 26, the secondary upper perforated washer 21, and the secondary upper perforated rib 15 in sequence according to the corresponding relationship of the holes, and then use bolts and nuts to tightly fix them to ensure that the material will not leak from the junction of the upper lower rib 12 and the secondary upper rib 1.

[0059] (4) Second step mixing:

[0060] Pour the required second-step mixed materials into the secondary mixing barrel body 17 and the upper mixing barrel body 24. Then, fit the upper perforated cover plate 23, the upper perforated gasket 28 and the upper perforated rib 23 in sequence according to the corresponding holes, and then use bolts and nuts to tightly fix them to form a closed mixing environment.

[0061] The secondary connecting arm 16 or the upper connecting arm 24 is connected to the external rotating shaft, and the rotating shaft drives the mixing barrel to rotate to achieve uniform mixing of the materials.

[0062] Example 3

[0063] like Figure 3 、 Figure 4The figures shown are schematic diagrams of the specific implementation process of the present invention. (1) After the bottom of the mixing device is sealed, the first step mixture is poured in. (2) After the upper opening of the mixing device is closed, the mixing operation is performed. (3) After the mixing is completed, the upper end seal of the mixing device is released to form an upper end open state. (4) Another mixing device is assembled above the above-mentioned mixing device to form an integrated mixing device. (5) The second step mixture is poured into the integrated mixing device. (6) After the upper opening of the integrated mixing device is closed, the mixing operation is performed.

[0064] The mixing device of the utility model performs multi-step mixing in a single mixing barrel, avoiding the transfer of materials between different mixing barrels, thereby significantly reducing material loss. The device has the characteristics of low cost, easy installation and disassembly, high practicality and wide application range.

[0065] The design of the mixing device allows the size and shape of the mixing barrel, as well as the configuration of the clamps and connecting arms to be adjusted according to specific needs to adapt to different mixing processes and material characteristics.

[0066] It is understood that the present invention is described by way of certain embodiments, and those skilled in the art will appreciate that various changes or equivalent substitutions may be made to these features and embodiments without departing from the spirit and scope of the present invention. Furthermore, under the guidance of the present invention, these features and embodiments may be modified to suit specific circumstances and materials without departing from the spirit and scope of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed herein, and all embodiments falling within the scope of the claims of this application are intended to be protected by the present invention.

Claims

1. A mixing device that can be assembled and separated, comprising a mixing device side wall, a lower closing portion, and an upper closing portion, characterized in that: The side wall of the mixing device forms a closed mixing operation space with the lower closing part and the upper closing part; the lower closing part includes a lower closing part assembly part and a lower closing part closing piece; the upper closing part includes an upper closing part assembly part and an upper closing part closing piece.

2. The mixing device according to claim 1, characterized in that The lower closure assembly part and the lower closure part closing piece are fixed by a lower fastener; the upper closure assembly part and the upper closure part closing piece are fixed by an upper fastener.

3. The mixing device according to claim 1 or 2, characterized in that The lower closing part also includes a lower closing part elastic part, which is located between the lower closing part assembly part and the lower closing part closing part during assembly; the upper closing part also includes an upper closing part elastic part, which is located between the upper closing part assembly part and the upper closing part closing part during assembly.

4. The mixing device according to claim 2, characterized in that A connecting arm is fixed to the side wall of the mixing device for connecting with an external rotating device.

5. The mixing device according to any one of claims 2 or 4, characterized in that There are one or more assembleable and separable mixing devices, and a plurality of assembleable and separable mixing devices are assembled to form an integrated mixing device.

6. The mixing device according to claim 5, characterized in that There are two assembleable and separable mixing devices, namely a secondary mixing device and an upper mixing device. The lower closing part assembly of the upper mixing device and the upper closing part assembly of the secondary mixing device are fixed by the upper fastener of the secondary mixing device.

7. The mixing device according to claim 6, characterized in that The upper closing part elastic member of the secondary mixing device is located between the upper closing part assembly part of the secondary mixing device and the lower closing part assembly part of the upper mixing device during assembly.

8. The mixing device according to any one of claims 1, 2, 4, 6 and 7, characterized in that: The lower closing part assembly part is configured as a ridge structure, and the lower closing part closing piece is a barrel cover; the upper closing part assembly part is configured as a ridge structure, and the upper closing part closing piece is a barrel cover.

9. The mixing device according to claim 8, characterized in that It also includes a lower closing part elastic part and an upper closing part elastic part, and holes are relatively provided around the lower closing part assembly part, the lower closing part elastic part and the lower closing part closing part; holes are relatively provided around the upper closing part assembly part, the upper closing part elastic part and the upper closing part closing part.

10. The mixing device according to any one of claims 2 or 6, characterized in that The lower fastening piece and the upper fastening piece are both clamp structures or bolt and nut structures.