Full-automatic liquid-based thin-layer cell sheet making machine

Abstract

The utility model discloses a full-automatic liquid-based thin-layer cell pelleter which is more convenient compared with a traditional sealing mode such as manual pressing and the like by adsorbing and fixing an opening and closing plate and an opening end through magnetic force of an electromagnet for the whole working environment, and meanwhile, an occlusal pad is additionally arranged to increase the sealing performance of an arc-shaped side surface, so that the production efficiency is improved. The stability of the temperature and the humidity of a working environment is ensured, the possibility that a sample is evaporated and dried is reduced, so that the uniformity of the sample is kept, the uniform mixing efficiency is improved by additionally arranging the uniform mixing mechanism, meanwhile, when the sample is output to the glass slide, a traditional needle center liquid outlet mode is changed into a circular ring liquid outlet mode, the uniform distribution of cells on the glass slide is ensured, and the cell quality is improved. The cell enrichment degree is ensured.

Description

Technical Field

[0001] The utility model belongs to the field of cell slide making machines, and in particular relates to a full-automatic liquid-based thin layer cell slide making machine. Background Art

[0002] The fully automatic liquid-based thin-layer cytology slide machine is a medical device used to prepare samples for cytology examinations. This machine is mainly used for gynecological screening, such as cervical cancer screening, and other types of cytology examinations, such as cytology of the respiratory tract, digestive tract, and urinary tract.

[0003] The use of fully automatic liquid-based thin-layer cell slide machines has greatly improved the efficiency and accuracy of cytological examinations, which is of great significance for the early detection and diagnosis of diseases. With the continuous advancement of technology, the functions and performance of such equipment are also constantly improving to meet the needs of clinical and scientific research.

[0004] In order to maintain the uniformity of the sample, it is necessary to control the temperature and humidity during the slide making process to prevent the sample from drying out or evaporating. At the same time, during the aspiration of the cell suspension, it is necessary to mix the internal cell suspension through reciprocating suction. However, if only relying on a single water flow for mixing, the dispersion and uniformity of the cells are poor. At the same time, when spraying onto the slide, it is also necessary to ensure the uniform distribution of the cells.

[0005] Therefore, how to increase the uniformity of absorption and cell enrichment and improve the accuracy of the results is a problem that needs to be solved. Utility Model Content

[0006] In response to the above defects, the present invention provides a fully automatic liquid-based thin layer cell slide making machine, comprising a slide making machine body, an opening end of the slide making machine body being hingedly connected to an opening and closing plate by a hinge, a sealing mechanism for increasing sealing performance is provided between the opening and closing plate and the opening end, the sealing mechanism comprising an electromagnet at the bottom of the opening and closing plate and a bite pad provided on the side of the opening end;

[0007] The liquid extraction gun inside the tablet making machine body includes a vacuum pump, a gun body and a needle tube. The vacuum pump is installed on the top of the gun body to provide suction pressure. The gun body and the needle tube are connected through a one-way valve. The inner bottom wall of the needle tube is inlaid with a sealing bottom plate. The sealing bottom plate is provided with several discharge holes in a circular array. The top end of the one-way valve passes through the sealing bottom plate and is installed with an input pipe, and a mixing mechanism is provided on the input pipe.

[0008] Furthermore, the bite pad is made of silicone rubber and has a U-shaped opening that matches the edge of the opening and closing plate, and the outer side height value of the U-shaped opening is greater than the inner side height value.

[0009] Through the above technical scheme, when sealing through the rotation of the hinged opening and closing plate, the edge of the opening and closing plate can be attached by the occlusal pad, the sealing property is increased, and the temperature and humidity of the internal environment are ensured.

[0010] Further, the opening end is inlaid with an iron block for magnetic adsorption on the side in contact with the electromagnet, and the outer ring of the electromagnet is wrapped with a rubber ring, and the height value of the rubber ring is greater than the height value of the electromagnet.

[0011] Through the above technical scheme, the stability of the sealing is ensured through magnetic adsorption, and the rubber ring which can be deformed can be compressed to reduce the gap between the opening end.

[0012] Further, the mixing mechanism is a plurality of communication holes formed on the surface of the input pipe, and the communication hole located at the bottom end is at the same horizontal position as the top end of the one-way valve.

[0013] Through the above technical scheme, the residual cell suspension in the input pipe is prevented from being discharged.

[0014] Further, the mixing mechanism is a plurality of fan leaves fixed to the outer surface of the input pipe, the input pipe and the one-way valve are connected through a bearing, and the inner wall of the gun body is fixed with a sloping flow guide plate.

[0015] Through the above technical scheme, when the internal cell suspension is mixed through repeated suction, the input pipe can be rotated by the fan leaves, so that the fan leaves rotate to realize stirring operation and improve the mixing efficiency.

[0016] The utility model has the following beneficial effects compared with prior art:

[0017] 1. For the overall working environment, the opening and closing plate and the opening end are fixed through the magnetic adsorption of the electromagnet, which is more convenient than the traditional manual compression sealing method, has better stability, and the occlusal pad is additionally provided to increase the sealing property of the arc side, ensure the stability of the working environment temperature and humidity, reduce the possibility of sample evaporation and drying, and maintain the uniformity of the sample.

[0018] 2. Through the mixing mechanism, the efficiency of mixing is improved after the traditional vacuum pump sucks the cell suspension of the liquid taking gun, and the internal mixing is realized through reciprocating suction, and the traditional needle center liquid outlet mode is changed to a circular ring liquid outlet mode when outputting to the glass slide, ensuring the uniform distribution of cells on the glass slide and ensuring the cell enrichment degree. BRIEF DESCRIPTION OF DRAWINGS

[0019] Figure 1 It is a perspective view of the utility model.

[0020] Figure 2It is the cross section view of the occlusion pad in the utility model.

[0021] Figure 3 It is the schematic view of the mixing structure in example 1.

[0022] Figure 4 It is the schematic view of the mixing structure in example 2.

[0023] Figure 5 It is Figure 4 The enlarged view of A in the middle.

[0024] In the figure: 1, tablet machine body; 2, open and close board; 3, occlusion pad; 4, electromagnet; 5, open end; 6, liquid taking gun; 61, gun body; 62, needle tube; 63, check valve; 64, sealing bottom plate; 65, discharge hole; 66, input pipe; 67, fan blade; 68, guide plate; 69, communication hole. DETAILED DESCRIPTION

[0025] In order to facilitate the understanding of the utility model, the device of the utility model will be described more fully below with reference to the relevant drawings. The drawings show the embodiments of the device. However, the device can be realized in many different forms and is not limited to the embodiments described herein. On the contrary, the purpose of providing these embodiments is to make the disclosure of the utility model more thorough and comprehensive.

[0026] In the description of the utility model, it should be pointed out that, unless otherwise explicitly specified and limited, the terms "mounting", "connection", "setting" should be understood broadly, for example, it can be fixedly connected, set, or it can be detachably connected, set, or integrally connected, set. For ordinary skilled in the art, the specific meaning of the above terms in the utility model can be understood according to the specific circumstances.

[0027] Example 1

[0028] As Figures 1-3 The embodiment provides a full-automatic liquid-based thin layer cell tablet machine, which comprises a tablet machine body 1, and it should be noted that the tablet machine body 1 is same as a conventional full-automatic cell tablet machine, comprising a sample processing unit, a smearing unit, a fixing unit, a dyeing unit, a control system, a touch screen, a conveying system and a cleaning unit, so as to realize the whole tablet process, from sample processing to smearing, fixing and dyeing, which are all automatically completed, and the error of manual operation is reduced, and here, excessive details are not described.

[0029] The open end 5 of the tablet machine body 1 is hingedly connected with a transparent opening and closing plate 2, and a sealing mechanism for increasing the sealing performance is arranged between the opening and closing plate 2 and the open end 5. The sealing mechanism comprises an electromagnet 4 at the bottom of the opening and closing plate 2 and a bite pad 3 arranged on the side of the open end 5. In detail, the bite pad 3 is made of silicone rubber (having the characteristics of high temperature resistance and moisture resistance) and is a U-shaped opening matching the edge of the opening and closing plate 2. The outside height of the U-shaped opening is greater than the inside height. When the open end 5 is sealed by the opening and closing plate 2, the two ends of the opening and closing plate 2 can be clamped into the inside of the bite pad 3. The design of different heights can prevent the inside from being blocked when inserted, and the opening and closing plate 2 is easier to insert. The side of the open end 5 in contact with the electromagnet 4 is embedded with an iron block for magnetic attraction. The outer ring of the electromagnet 4 is wrapped with a rubber ring (which can also be made of silicone rubber). The height of the rubber ring is greater than the height of the electromagnet 4. When the electromagnet 4 is electrified, it can be magnetically attracted to the iron block, increasing the stability of the sealing state of the opening and closing plate 2. At the same time, the magnetic attraction compresses the rubber ring to deform, filling and sealing the gap of the open end.

[0030] The liquid taking gun 6 in the tablet machine body 1 comprises a vacuum pump, a gun body 61 and a needle tube 62. The vacuum pump installed on the top of the gun body 61 provides suction pressure, the gun body 61 is communicated with the needle tube 62 through a one-way valve 63, and the one-way valve 63 can enter the inside of the gun body 61 but cannot output from it, ensuring that the cell suspension can be output from the mixing mechanism. The inner bottom wall of the needle tube 62 is embedded with a sealing bottom plate 64, and a plurality of discharge holes 65 in the form of a ring array are arranged on the sealing bottom plate 64 to discharge the cell suspension in the inside to the slide. It should be noted that the direction of the discharge hole 65 should be inclined towards the center of the sealing bottom plate 64 to ensure that the discharge hole 65 is in the center of the slide. The top end of the one-way valve 63 penetrates the sealing bottom plate 64 and is provided with an input pipe 66. The input pipe 66 is provided with a mixing mechanism. The mixing mechanism comprises a plurality of communication holes 69 arranged on the surface of the input pipe 66. When the cell suspension in the gun body 61 is mixed and suctioned, the cell suspension is discharged and suctioned from each communication hole 69, which is equivalent to increasing the partition in the gun body 61 to block the cell suspension and improve the mixing efficiency. The communication hole 69 at the bottom end is at the same horizontal position as the top end of the one-way valve 63, which can prevent the residual cell suspension in the input pipe 66 from being discharged.

[0031] Example 2

[0032] As Figures 4-5The difference from the above embodiment 1 is that the mixing mechanism is a plurality of blades 67 fixed on the outer surface of the input pipe 66, the input pipe 66 is connected with the one-way valve 63 through a bearing (a sealing ring should be added), and the inner wall of the gun body 61 is fixed with a slope guide plate 68, the cell suspension in the gun body 61 is moved up and down by the suction of the vacuum pump, at this time, the up and down end flow guiding (i.e. the starting and ending of the water column formed by the cell suspension) is carried out through the slope guide plate 68 of the side wall, the forward rotation or reverse rotation of the blade 67 with a specific curved surface is driven (such as the curved surface of the fan blade, which can better guide the water flow, so that the blade 67 can be pushed to rotate through the curved surface when the water flow passes through), so that the mixing efficiency of the cell suspension is improved.

[0033] It should be noted that the structure of the utility model can be realized in many different forms, and is not limited to the embodiments, and any equivalent transformation made by those skilled in the art using the contents of the utility model specification and drawings, or direct or indirect application in other related technical fields, such as other article loading and unloading, are all included in the protection scope of the utility model.

Claims

1. A fully automatic liquid-based thin-layer cell preparator comprising a preparator body, characterized in that: The open end of the tablet machine body is hinged with an opening and closing plate through a hinge, a sealing mechanism for increasing the sealing performance is arranged between the opening and closing plate and the open end, the sealing mechanism comprises an electromagnet at the bottom of the opening and closing plate and a bite pad arranged on the side of the open end; The liquid taking gun in the tablet machine body comprises a vacuum pump, a gun body and a needle tube, the vacuum pump is installed at the top of the gun body for providing suction pressure, the gun body and the needle tube are communicated through a one-way valve, the inner bottom wall of the needle tube is inlaid with a sealing bottom plate, a plurality of discharge holes in annular array are arranged at the sealing bottom plate, the top end of the one-way valve penetrates the sealing bottom plate and is installed with an input pipe, and a mixing mechanism is arranged at the input pipe.

2. The fully automatic liquid-based thin-layer cell preparer according to claim 1, wherein: The bite pad is made of silicone rubber and has a U-shaped opening matched with the edge of the opening and closing plate, the outside height of the U-shaped opening is greater than the inside height.

3. The fully automatic liquid-based thin-layer cell preparer according to claim 1, wherein: An iron block for magnetic adsorption is inlaid on the side of the open end in contact with the electromagnet, and a rubber ring is wrapped around the outer ring of the electromagnet, the height of the rubber ring is greater than the height of the electromagnet.

4. The fully automatic liquid-based thin-layer cell preparer according to claim 1, wherein: The mixing mechanism is a plurality of communication holes arranged on the surface of the input pipe, and the communication hole at the bottom end is at the same horizontal position as the top end of the one-way valve.

5. The fully automatic liquid-based thin-layer cell preparer according to claim 1, wherein: The mixing mechanism is a plurality of fan blades fixed on the outer surface of the input pipe, the input pipe and the one-way valve are connected through a bearing, and the inner wall of the gun body is fixed with a slope guide plate.

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