Vibrating and uniform mixing device for biological cell culture

Abstract

The utility model discloses a biological cell culture shaking and blending device which comprises a bottom plate, two symmetrical sliding grooves are formed in the upper end of the bottom plate, sliding plates are connected into the sliding grooves in a sliding mode, a blending cylinder is fixedly installed at the upper ends of the two sliding plates together, and a cylinder cover is arranged at the upper end of the blending cylinder. A rotating mechanism for uniformly mixing cells is arranged in the uniform mixing cylinder, a reciprocating mechanism for enabling the uniform mixing cylinder to reciprocate left and right is arranged at the lower end of the uniform mixing cylinder, and a double-shaft motor for driving the rotating mechanism and the reciprocating mechanism is fixedly mounted at the inner bottom of the uniform mixing cylinder. According to the utility model, the rotation and left-right movement of the culture tube are realized through the matching of the rotating mechanism and the reciprocating mechanism, the mixing cylinder generates an oscillation effect under the double-layer action, and the oscillation and shaking-up speed of biological cells is accelerated.

Description

Technical Field

[0001] This utility model relates to the field of mixing device technology, and in particular to a biological cell culture shaking mixing device. Background Technology

[0002] A search revealed a patent with publication number "CN217809496U" entitled "A Shaking Mixing Device for Biological Cell Culture," relating to the field of biological cell technology. The device includes a housing with an inner shell inside. The bottom of the inner shell is connected to a rod via two rings. A ring-shaped disk is fixedly connected to the top of the inner shell, and a rotating disk is located in the center of the ring-shaped disk. The bottom of the rotating disk is fixedly connected to a rotary motor. A fixed rod is fixedly connected between the inner walls of the grooves in the ring-shaped disk. A transmission rod is rotatably sleeved on the outer wall of the fixed rod. The other end of the transmission rod is rotatably sleeved on an eccentric block on the outer wall of an eccentric wheel. The shaft of the eccentric wheel is fixedly connected to a shaking motor. By using a rotary motor and a shaking motor in conjunction with the eccentric wheel and transmission rod, the biological cell culture tubes on the rotating disk can oscillate up and down while rotating, accelerating the shaking and mixing speed. The entire device is small in size, making it easy to install and use. Furthermore, the oscillation method using the side vibration of the eccentric wheel avoids gear wear and extends its service life. This patent primarily uses the method of oscillating the culture tubes for mixing, which can easily cause cells to be shaken out.

[0003] The patent publication number is "CN214032529U". It describes a vibrating mixing device for biological cell culture, comprising a base plate, an anti-slip pad fixedly connected to the bottom of the base plate, shock-absorbing cotton fixedly connected to the top of the base plate, a buffer pad fixedly connected to the top of the shock-absorbing cotton, a connecting plate fixedly connected to the top of the buffer pad, a first motor fixedly connected to the top of the connecting plate, a first connecting rod fixedly connected to the output shaft of the first motor via a coupling, a rotating shaft fixedly connected to the outer wall of the first connecting rod, and a gear fixedly connected to the outer wall of the rotating shaft. This vibrating mixing device for biological cell culture achieves good mixing effect, greatly improving the working efficiency of the device and also improving the work efficiency of people, reducing their work pressure, and bringing convenience to their work. It is worthy of widespread use. This patent utilizes the cooperation of gears, upper saw teeth, and lower saw teeth to achieve left and right movement of the vibrating box. During the left and right movement, the gears, upper saw teeth, and lower saw teeth rub and collide with each other, further aggravating wear. Utility Model Content

[0004] The purpose of this invention is to address the shortcomings of existing technologies by proposing a biological cell culture oscillation and mixing device. It utilizes the combination of a rotating mechanism and a reciprocating mechanism to achieve the rotation and left-right movement of the culture tube. The double-layer action causes the mixing cylinder to produce an oscillation effect, thereby accelerating the oscillation and mixing speed of biological cells.

[0005] To achieve the above objectives, the present invention adopts the following technical solution:

[0006] A biological cell culture shaking and mixing device includes a base plate, two symmetrical grooves are provided on the upper end of the base plate, a sliding plate is slidably connected inside the groove, a mixing cylinder is fixedly installed on the upper end of the two sliding plates, and a cylinder cover is provided on the upper end of the mixing cylinder.

[0007] The mixing cylinder is equipped with a rotating mechanism for cell mixing, and a reciprocating mechanism for left and right reciprocating motion of the mixing cylinder is provided at the lower end of the mixing cylinder. A dual-axis motor for driving the rotating mechanism and the reciprocating mechanism is fixedly installed at the inner bottom of the mixing cylinder.

[0008] Preferably, the rotating mechanism includes a support plate fixedly installed on the upper end of a dual-axis motor, and a plurality of vertical rods are fixedly installed at equal intervals on the upper end of the support plate, with a top plate fixedly installed on the upper end of the plurality of vertical rods.

[0009] Preferably, the upper surface of the tray has a plurality of grooves evenly distributed for supporting the culture tubes.

[0010] Preferably, the top plate is provided with a plurality of through holes for limiting the upper section of the culture tube.

[0011] Preferably, the reciprocating mechanism includes a cam fixedly mounted on the lower end of the dual-axis motor, and a fixed wheel is rotatably connected to the upper end of the base plate, the fixed wheel being in contact with the cam.

[0012] Preferably, the slide plate and the slide groove are elastically connected by a spring.

[0013] This utility model has the following beneficial effects:

[0014] 1. Through the design of the rotating mechanism, the dual-axis motor drives the tray to rotate, which in turn causes the culture tube to rotate, thus initially shaking the culture tube and facilitating cell mixing.

[0015] 2. Through the design of the reciprocating mechanism, during the rotation of the cam, the fixed wheel and the spring cooperate to realize the left and right movement of the slide plate, thereby making the mixing cylinder produce an oscillation effect and accelerating the oscillation and mixing speed of biological cells. Attached Figure Description

[0016] Figure 1 This is a schematic diagram of the structure of a biological cell culture shaking and mixing device proposed in this utility model;

[0017] Figure 2 This is a side view of a biological cell culture shaking and mixing device proposed in this utility model;

[0018] Figure 3This is a cross-sectional view of a biological cell culture shaking and mixing device proposed in this utility model.

[0019] In the diagram: 1. Base plate, 2. Spring, 3. Mixing cylinder, 4. Slide groove, 5. Cylinder cover, 6. Cam, 7. Fixed wheel, 8. Slide plate, 9. Dual-axis motor, 10. Support plate, 11. Vertical rod, 12. Top plate. Detailed Implementation

[0020] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments.

[0021] In the description of this utility model, it should be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0022] Reference Figures 1-3 A biological cell culture shaking and mixing device includes a base plate 1, two symmetrical sliding grooves 4 are opened at the upper end of the base plate 1, a sliding plate 8 is slidably connected inside the sliding groove 4, a mixing cylinder 3 is fixedly installed at the upper end of the two sliding plates 8, and a cylinder cover 5 is provided at the upper end of the mixing cylinder 3.

[0023] The mixing cylinder 3 is equipped with a rotating mechanism for cell mixing. The rotating mechanism includes a support plate 10 fixedly installed on the upper end of the dual-axis motor 9. Multiple vertical rods 11 are fixedly installed at equal intervals on the upper end of the support plate 10. A top plate 12 is fixedly installed on the upper end of the multiple vertical rods 11. Multiple grooves for supporting culture tubes are evenly distributed on the upper surface of the support plate 10. Multiple through holes for limiting the upper section of the culture tube are evenly distributed on the top plate 12.

[0024] The lower end of the mixing cylinder 3 is provided with a reciprocating mechanism for the mixing cylinder 3 to move back and forth. The reciprocating mechanism includes a cam 6 fixedly installed at the lower end of the dual-axis motor 9. A fixed wheel 7 is rotatably connected to the upper end of the base plate 1. The fixed wheel 7 and the cam 6 are in contact with each other. The slide plate 8 and the slide groove 4 are elastically connected by a spring 2. The inner bottom of the mixing cylinder 3 is fixedly installed with a dual-axis motor 9 for driving the rotation mechanism and the reciprocating mechanism.

[0025] Working principle:

[0026] In use, open the tube cap 5, place the culture tube into the through hole, with the bottom in the groove, close the tube cap 5, and then start the dual-axis motor 9. The dual-axis motor 9 drives the support plate 10 and cam 6 to rotate. The rotation of the support plate 10 can rotate the culture tube. During the rotation of the cam 6, the fixed wheel 7 cooperates with the spring 2 to realize the left and right movement of the slide plate 8, thereby making the mixing tube 3 vibrate and accelerating the shaking speed of biological cells. After the mixing is completed, turn off the dual-axis motor 9, open the tube cap 5, and take out the culture tube.

[0027] The above are merely preferred embodiments of this utility model, but the scope of protection of this utility model is not limited thereto. Any equivalent substitutions or modifications made by those skilled in the art within the scope of the technology disclosed in this utility model, based on the technical solution and inventive concept of this utility model, should be included within the scope of protection of this utility model.

Claims

1. A biological cell culture shaking and mixing device, comprising a base plate (1), characterized in that: The upper end of the base plate (1) is provided with two symmetrical sliding grooves (4), and the sliding grooves (4) are slidably connected to the sliding plate (8). The upper ends of the two sliding plates (8) are fixedly installed with a mixing cylinder (3), and the upper end of the mixing cylinder (3) is provided with a cylinder cover (5). The mixing cylinder (3) is equipped with a rotating mechanism for cell mixing inside, and a reciprocating mechanism for the mixing cylinder (3) to move back and forth left and right is provided at the lower end of the mixing cylinder (3). A dual-axis motor (9) for driving the rotating mechanism and the reciprocating mechanism is fixedly installed at the inner bottom of the mixing cylinder (3).

2. The biological cell culture shaking and mixing device according to claim 1, characterized in that, The rotating mechanism includes a support plate (10) fixedly installed on the upper end of a dual-axis motor (9). Multiple vertical rods (11) are fixedly installed at equal intervals on the upper end of the support plate (10), and a top plate (12) is fixedly installed on the upper end of the multiple vertical rods (11).

3. The biological cell culture shaking and mixing device according to claim 2, characterized in that, The upper surface of the tray (10) is evenly distributed with multiple grooves for supporting the culture tubes.

4. The biological cell culture shaking and mixing device according to claim 2, characterized in that, The top plate (12) is evenly distributed with multiple through holes for limiting the upper section of the culture tube.

5. The biological cell culture shaking and mixing device according to claim 1, characterized in that, The reciprocating mechanism includes a cam (6) fixedly installed at the lower end of the dual-axis motor (9), and a fixed wheel (7) rotatably connected to the upper end of the base plate (1), with the fixed wheel (7) and the cam (6) in contact with each other.

6. The biological cell culture shaking and mixing device according to claim 5, characterized in that, The slide plate (8) and the slide groove (4) are elastically connected by a spring (2).

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