Bottle rotating device for cell culture

Abstract

The utility model relates to a spinner bottle device for cell culture, which belongs to the technical field of cell culture and comprises a bottom plate, a first support plate and a second support plate, two side plates are fixedly mounted on the upper surface of the bottom plate, and a rotating shaft adjusting mechanism is arranged among the bottom plate, the first support plate and the second support plate. The rotating shaft adjusting mechanism comprises a threaded rod and a limiting rod which are fixedly mounted between the surfaces of the opposite sides of the two side plates, a mounting hole is formed in the first supporting plate, a threaded sleeve which is in threaded connection to the surface of the threaded rod is rotatably mounted in the mounting hole, and a limiting hole is formed in the second supporting plate. According to the bottle rotating device for cell culture, the rotating shaft adjusting mechanisms are arranged among the bottom plate, the first supporting plate and the second supporting plate, and the distance between every two adjacent rotating shafts can be adjusted when the bottle rotating device is used, so that the distance between every two adjacent rotating shafts can adapt to culture bottles with different diameters, and the adaptability of the bottle rotating device is greatly improved.

Description

Technical Field

[0001] This utility model relates to the field of cell culture technology, specifically a rotary bottle device for cell culture. Background Technology

[0002] Cell culture is a fundamental technique in biological and medical research, involving the growth and propagation of cells in an in vitro environment. It is widely used in basic research, drug development, vaccine production, tissue engineering, and other fields. A roller bottle device is a piece of equipment used for cell culture, typically to provide a uniform supply of nutrients and gas exchange during the culture process to promote cell growth and proliferation.

[0003] CN206553535U discloses a cell culture rotary bottle device. The support frame includes multiple support rods fixedly connected to each other, forming a cuboid frame. Two ends of a rotating shaft are rotatably mounted on slides, allowing rotation on the slides. The slides are slidably mounted on two parallel slide rails on the support frame, enabling movement along the slide rails, i.e., along the length of the support rods. A spacing adjustment device is rotatably mounted on a support rod of the support frame. The spacing adjustment device drives the slides to translate via a transmission device, converting the rotation of the spacing adjustment device into the translation of the slides. Rotating the spacing adjustment device changes the spacing between the two rotating shafts. The spacing between the two rotating shafts is set according to the different diameters of the culture bottles. After the spacing is adjusted, a controller mounted on the support frame controls the rotation of the rotating shafts, which further drives the culture bottles to rotate.

[0004] The aforementioned patent addresses the shortcomings of existing bottle-turning devices, such as the inability to adjust the distance between two adjacent rotating shafts, the fact that certain models of bottle turners can only operate on culture bottles of specific sizes, and the extremely limited application range. This application provides another implementation method to address the problems raised in the aforementioned patent. Utility Model Content

[0005] To address the shortcomings of existing technologies, this invention provides a rotary bottle device for cell culture, which has the advantage of wide applicability. It solves the problems of existing rotary bottle devices where the distance between two adjacent rotating shafts cannot be adjusted, and certain models of rotary bottle machines can only operate on culture flasks of specific sizes, thus greatly limiting their application range.

[0006] To achieve the above objectives, the present invention provides the following technical solution: a rotary bottle device for cell culture, comprising a base plate, a first support plate and a second support plate, wherein two side plates are fixedly installed on the upper surface of the base plate, and a rotating shaft adjustment mechanism is provided between the base plate, the first support plate and the second support plate;

[0007] The rotating shaft adjustment mechanism includes a threaded rod and a limiting rod fixedly installed between the opposite surfaces of the two side plates. The first support plate has an installation hole inside, and a threaded sleeve threaded to the surface of the threaded rod is rotatably installed inside the installation hole. The second support plate has a limiting hole inside, and the limiting rod is located inside the limiting hole. A rotating shaft is rotatably installed between the first support plate and the second support plate. A motor whose output end is fixedly connected to the rotating shaft is fixedly installed on the surface of the second support plate away from the first support plate.

[0008] Furthermore, both ends of the threaded sleeve are fixedly installed with limiting sleeves that are sleeved on the surface of the threaded rod, and the limiting sleeves are located outside the mounting hole.

[0009] The beneficial effect of adopting the above-mentioned further solution is that it helps to prevent the threaded sleeve from detaching from the mounting hole.

[0010] Furthermore, the base plate has two limiting grooves on its surface, which are located directly below the threaded rod and the limiting rod, respectively. The first support plate and the second support plate are respectively inserted into the two limiting grooves.

[0011] The beneficial effect of adopting the above-mentioned further solution is that it helps to improve the stability of the first support plate and the second support plate when they move.

[0012] Furthermore, there are three of each of the first and second support plates, and the number of the rotating shafts corresponds to the number of the first and second support plates.

[0013] The advantage of adopting the above-mentioned further scheme is that it makes it easier to place the culture flask between two adjacent rotating shafts for rotation.

[0014] Furthermore, a stabilizing rod is fixedly installed between the first support plate and the second support plate, and a supporting pulley is fixedly installed on the surface of the stabilizing rod.

[0015] The beneficial effect of adopting the above-mentioned further solution is that it helps to improve the connection stability between the first support plate and the second support plate.

[0016] Furthermore, a fixing frame is fixedly installed on the surface of the motor, and the fixing frame is fixedly connected to the surface of the second support plate.

[0017] The beneficial effect of adopting the above-mentioned further solutions is that it helps to improve the stability of the motor during operation.

[0018] Compared with the prior art, the technical solution of this application has the following beneficial effects:

[0019] This cell culture rotary bottle device features a rotating shaft adjustment mechanism between the base plate, the first support plate, and the second support plate. This mechanism allows for adjustment of the distance between adjacent rotating shafts, accommodating culture bottles of different diameters. This significantly improves the adaptability of the rotary bottle device and solves the problem in existing rotary bottle devices where the distance between adjacent rotating shafts cannot be adjusted, and certain models of rotary bottle machines can only operate on culture bottles of specific sizes, severely limiting their application range. Attached Figure Description

[0020] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0021] Figure 2 This is a schematic diagram of the structure of the first support plate and the second support plate of this utility model;

[0022] Figure 3 This is a schematic diagram of the base plate structure of this utility model;

[0023] Figure 4 This is a schematic diagram of the threaded sleeve structure of this utility model.

[0024] In the diagram: 1. Base plate; 2. Side plate; 3. Threaded rod; 4. Limiting rod; 5. First support plate; 6. Second support plate; 7. Mounting hole; 8. Threaded sleeve; 9. Limiting hole; 10. Rotating shaft; 11. Motor; 12. Limiting sleeve; 13. Limiting groove; 14. Stabilizing rod; 15. Support pulley; 16. Fixing frame. Detailed Implementation

[0025] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0026] Please see Figures 1 to 4This embodiment provides a cell culture rotary bottle device, including a base plate 1, a first support plate 5, and a second support plate 6. Two side plates 2 are fixedly installed on the upper surface of the base plate 1. A shaft adjustment mechanism is provided between the base plate 1, the first support plate 5, and the second support plate 6. The shaft adjustment mechanism includes a threaded rod 3 and a limiting rod 4 fixedly installed between opposite surfaces of the two side plates 2. A mounting hole 7 is provided inside the first support plate 5. A threaded sleeve 8, threaded to the surface of the threaded rod 3, is rotatably installed inside the mounting hole 7. Limiting sleeves 12, which are sleeved on the surface of the threaded rod 3, are fixedly installed at both ends of the threaded sleeve 8. The limiting sleeves 12 are located outside the mounting hole 7, which helps to prevent the threaded sleeve 8 from falling out of the mounting hole 7. The second support plate 6 is disengaged from the mounting hole 7. A limiting hole 9 is opened inside the second support plate 6, and the limiting rod 4 is located in the limiting hole 9. A rotating shaft 10 is rotatably installed between the first support plate 5 and the second support plate 6. A motor 11 with its output end fixedly connected to the rotating shaft 10 is fixedly installed on the surface of the second support plate 6 away from the first support plate 5. There are three first support plates 5 and three second support plates 6. The number of rotating shafts 10 corresponds to the number of first support plates 5 and two second support plates 6, which makes it easy to place the culture bottle between two adjacent rotating shafts 10 for rotation. A fixing frame 16 is fixedly installed on the surface of the motor 11. The fixing frame 16 is fixedly connected to the surface of the second support plate 6, which helps to improve the stability of the motor 11 during operation.

[0027] The base plate 1 has two limiting grooves 13 on its surface. The two limiting grooves 13 are located directly below the threaded rod 3 and the limiting rod 4, respectively. The first support plate 5 and the second support plate 6 are respectively inserted into the two limiting grooves 13, which helps to improve the stability of the first support plate 5 and the second support plate 6 when they move.

[0028] The working principle of the above embodiments is as follows:

[0029] In use, by rotating the limiting sleeve 12, the threaded sleeve 8 is driven to rotate, causing the threaded sleeve 8 to move on the threaded rod 3. This allows the first support plate 5 to move along the axial direction of the threaded rod 3. The second support plate 6 can move synchronously with the first support plate 5 on the limiting rod 4 via the stabilizing rod 14 and the support pulley 15. This allows the rotating shaft 10 to move, and the rotating shaft 10 can be driven to rotate via the motor 11 to rotate the bottle.

[0030] The control method of this utility model is through a controller. The control circuit of the controller can be implemented by simple programming by those skilled in the art. The power supply is also common knowledge in the field. Since this utility model is mainly used to protect mechanical devices, the control method and circuit connection will not be explained in detail.

[0031] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitations, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes said element.

[0032] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A rotary bottle device for cell culture, comprising a base plate (1), a first support plate (5), and a second support plate (6), wherein two side plates (2) are fixedly installed on the upper surface of the base plate (1), characterized in that: A rotating shaft adjustment mechanism is provided between the base plate (1), the first support plate (5), and the second support plate (6); The rotating shaft adjustment mechanism includes a threaded rod (3) and a limiting rod (4) fixedly installed between the opposite surfaces of the two side plates (2). The first support plate (5) has an installation hole (7) inside, and a threaded sleeve (8) threaded to the surface of the threaded rod (3) is rotatably installed inside the installation hole (7). The second support plate (6) has a limiting hole (9) inside, and the limiting rod (4) is located inside the limiting hole (9). A rotating shaft (10) is rotatably installed between the first support plate (5) and the second support plate (6). A motor (11) whose output end is fixedly connected to the rotating shaft (10) is fixedly installed on the surface of the second support plate (6) away from the first support plate (5).

2. The roller bottle device for cell culture according to claim 1, characterized in that: Both ends of the threaded sleeve (8) are fixedly installed with limiting sleeves (12) that are sleeved on the surface of the threaded rod (3), and the limiting sleeves (12) are located outside the mounting hole (7).

3. The roller bottle device for cell culture according to claim 1, characterized in that: The base plate (1) has two limiting grooves (13) on its surface. The two limiting grooves (13) are located directly below the threaded rod (3) and the limiting rod (4), respectively. The first support plate (5) and the second support plate (6) are respectively inserted into the two limiting grooves (13).

4. The roller bottle device for cell culture according to claim 1, characterized in that: The number of the first support plate (5) and the second support plate (6) are both three, and the number of the rotating shafts (10) corresponds to the number of the first support plate (5) and the second support plate (6).

5. The roller bottle device for cell culture according to claim 1, characterized in that: A stabilizing rod (14) is fixedly installed between the first support plate (5) and the second support plate (6), and a supporting pulley (15) is fixedly installed on the surface of the stabilizing rod (14).

6. The roller bottle device for cell culture according to claim 1, characterized in that: A fixing frame (16) is fixedly installed on the surface of the motor (11), and the fixing frame (16) is fixedly connected to the surface of the second support plate (6).

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