Multi-component assembled rapid detection box based on nucleic acid-protein coupling system

Abstract

The utility model relates to a nucleic acid-protein coupling system-based multi-component assembled fast detection box, which comprises a detection box, a connecting assembly is arranged on the detection box, the connecting assembly comprises an alignment piece and a plug connector which are arranged on the left side and the right side of the detection box, and the alignment piece and the plug connector are matched with each other, so that the nucleic acid-protein coupling system-based multi-component assembled fast detection box is formed. The two groups of detection boxes can be assembled and connected; a positioning mechanism is further arranged in the detection box, the positioning mechanism comprises a triggering assembly and a locking assembly, the triggering assembly comprises a triggering plate arranged on the U-shaped piece, the locking assembly comprises a locking piece arranged on the detection box in a sliding mode, and when the two groups of detection boxes are assembled and connected, the locking piece is arranged on the U-shaped piece in a sliding mode. Wherein one group of detection boxes can push the trigger plate to slide relative to the detection boxes, and then the locking assembly is driven to act to enable the locking piece to slide relative to the detection boxes, so that the connection state of the two groups of detection boxes is locked.

Description

Technical Field

[0001] This utility model relates to a multi-component assembled rapid test kit based on a nucleic acid-protein conjugate system. Background Technology

[0002] Cowpox virus is an acute infectious disease caused by bovine smallpox virus. It can be transmitted to humans through contact, and is most common among milkers and slaughterhouse workers. Patients develop papules on their skin, which gradually develop into vesicles and pustules, along with other symptoms. The virus can also be found in cattle, cats, and field mice. To prevent the entry of animals infected with cowpox virus into the country, it is necessary to test foreign animals for important animal health and safety risks.

[0003] Currently, when detecting the virulence genes of the vaccinia virus genus, it is necessary to simultaneously detect LSDV, poxvirus, and Akabane disease. There are currently test kits available on the market for detecting these three viruses. When testing animals for vaccinia virus, the testing personnel usually carry multiple test kits with different detection effects. These test kits look similar and have no obvious distinguishing features. Therefore, during the testing process, the operator needs to search for different test kits one by one, which takes a long time. Furthermore, it cannot be guaranteed that the test kit found each time is the one needed, which brings inconvenience to the testing process. Utility Model Content

[0004] The purpose of this invention is to provide a multi-component assembly rapid test kit based on a nucleic acid-protein conjugate system to solve the problems mentioned in the background art.

[0005] To achieve the above objectives, this utility model provides the following technical solution:

[0006] A multi-component rapid test kit based on a nucleic acid-protein conjugation system includes: a test box, wherein the test box is provided with a connecting component, the connecting component includes alignment members and plug-in members disposed on the left and right sides of the test box, and the two sets of the test boxes can be assembled and connected by the cooperation between the alignment members and the plug-in members.

[0007] The detection box is also equipped with a positioning mechanism, which includes a triggering component and a locking component. The triggering component includes a trigger plate disposed on the U-shaped component, and the locking component includes a locking member slidably disposed on the detection box. When assembling and connecting the two sets of detection boxes, one set of detection boxes can push the trigger plate to slide relative to the detection box, thereby driving the locking component to move so that the locking member slides relative to the detection box, thereby locking the connection state of the two sets of detection boxes.

[0008] The multi-component assembled rapid test kit based on the nucleic acid-protein conjugation system described above: the alignment component includes a U-shaped component disposed on the side of the test kit, and an alignment block is disposed on the side wall of the U-shaped component.

[0009] The multi-component assembled rapid test kit based on the nucleic acid-protein conjugation system described above: the connector includes a connector block disposed on the test kit, and the connector block has a slot adapted to the alignment block.

[0010] As described above, the multi-component assembly rapid test kit based on the nucleic acid-protein conjugation system includes a triggering component that further comprises a movable plate. The movable plate is slidably connected to a guide rod disposed within the test kit. Two sets of guide rods are provided, and a second spring is slidably disposed on each set of guide rods. One end of the second spring abuts against the test kit, and the other end abuts against the movable plate.

[0011] As described above, the multi-component assembled rapid test kit based on the nucleic acid-protein conjugation system has the following features: a fitting groove is provided on the moving plate, and a sliding rod fixedly connected to the trigger plate is slidably disposed in the fitting groove. When the trigger plate slides, the sliding rod cooperates with the fitting groove to drive the moving plate to slide along the width direction of the test kit.

[0012] The multi-component assembly rapid test kit based on the nucleic acid-protein conjugation system described above: the locking component includes an instantaneous structure and a trigger, the trigger including a drive gear plate fixedly connected to the moving plate, the drive gear plate engaging with a gear rotatably installed inside the test kit.

[0013] The multi-component rapid test kit based on the nucleic acid-protein conjugation system described above: the instantaneous structure includes a stabilizing plate fixedly installed inside the test kit, an upper baffle and a lower baffle provided on the stabilizing plate, and a deflecting plate rotatably installed on the stabilizing plate, the rotating shaft of the deflecting plate being coaxially fixed with the gear, and the deflecting plate being connected to the stabilizing plate through a first spring.

[0014] The multi-component assembly rapid test kit based on the nucleic acid-protein conjugation system described above: the locking element includes a locking block slidably disposed on the test kit, the locking block is provided with a driven toothed plate, and the driven toothed plate meshes with the gear.

[0015] Compared with the prior art, the beneficial effects of this utility model are:

[0016] By setting up a connecting component and utilizing the cooperation between the alignment component and the plug-in component, the connection between two sets of detection boxes can be realized. By setting up a positioning mechanism, when the two sets of detection boxes are connected, the cooperation between the trigger component and the locking component can drive the locking block that is slidably set on the detection box to move closer to the trigger block along the span direction of the detection box, thereby locking the connection state of the detection box.

[0017] With the cooperation of the connecting components and the positioning mechanism, the test boxes can be assembled and spliced ​​to form a multi-component assembly quick test box. Compared with a single test box, the assembled test box is larger in size and easier to find. Moreover, the multi-component quick test box, which is spliced ​​according to the usage requirements, is easy to use. There is no need to search for the required test boxes one by one, making it more convenient and faster to use. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the structure of a multi-component rapid test kit based on a nucleic acid-protein conjugate system.

[0019] Figure 2 This is a schematic diagram of the connecting components in a multi-component rapid test kit based on a nucleic acid-protein conjugation system.

[0020] Figure 3 This is a schematic diagram of the internal structure of the test kit in a multi-component assembled rapid test kit based on a nucleic acid-protein conjugation system.

[0021] Figure 4 This is a schematic diagram of the positioning mechanism in a multi-component rapid test kit based on a nucleic acid-protein conjugation system.

[0022] Figure 5 This is a schematic diagram of the trigger component in a multi-component rapid test kit based on a nucleic acid-protein conjugation system.

[0023] Figure 6 This is a schematic diagram of the transient structure in a multi-component rapid test kit based on a nucleic acid-protein conjugation system.

[0024] Figure 7 This is a schematic diagram of the connection between the stabilizing plate and the deflecting plate in a multi-component assembly rapid test kit based on a nucleic acid-protein coupling system.

[0025] In the diagram: 1. Detection box; 2. U-shaped component; 201. Alignment block; 3. Insertion block; 301. Slot; 4. Locking block; 5. Trigger plate; 501. Slide rod; 6. Moving plate; 601. First vertical slot; 602. Inclined slot; 603. Second vertical slot; 7. Guide rod; 8. Test paper; 9. Stabilizing plate; 901. Upper baffle; 902. Lower baffle; 10. Deflection plate; 11. Drive gear plate; 12. Gear; 13. Driven gear plate; 14. First spring; 15. Second spring. Detailed Implementation

[0026] Various exemplary embodiments, features, and aspects of this application will now be described in detail with reference to the accompanying drawings. The same reference numerals in the drawings denote elements that have the same or similar functions. Although various aspects of the embodiments are shown in the drawings, they are not necessarily drawn to scale unless specifically indicated otherwise.

[0027] The term “exemplary” as used herein means “serving as an example, embodiment, or illustration.” Any embodiment illustrated herein as “exemplary” is not necessarily to be construed as superior to or better than other embodiments.

[0028] Furthermore, to better illustrate this application, numerous specific details are provided in the following detailed embodiments. Those skilled in the art should understand that this application can be implemented even without certain specific details. In some instances, methods, means, and elements well-known to those skilled in the art have not been described in detail in order to highlight the main points of this application.

[0029] Please see Figures 1-7 In this embodiment of the invention, the multi-component assembled rapid test kit based on a nucleic acid-protein conjugate system includes:

[0030] The detection box 1 is provided with a connecting component, which includes alignment parts and plug-in parts disposed on the left and right sides of the detection box 1. With the cooperation between the alignment parts and plug-in parts, two sets of the detection boxes 1 can be assembled and connected.

[0031] The alignment component includes a U-shaped component 2 disposed on the side of the detection box 1, and an alignment block 201 is disposed on the side wall of the U-shaped component 2;

[0032] The connector includes a connector block 3 disposed on the detection box 1, and the connector block 3 has a slot 301 adapted to the alignment block 201;

[0033] For details, please refer to Figure 1 , Figure 2 , Figure 3 The above-mentioned test kit 1 is equipped with test strips 8. Different types of test strips 8 can be used to detect different viruses. In particular, when detecting the virulence gene of the vaccinia virus genus, it is necessary to detect LSDV, poxvirus genus and Akabane disease at the same time. At this time, by using the test kit 1 containing the corresponding test strips 8, the detection of LSDV, poxvirus genus and Akabane disease can be completed.

[0034] Currently, different detection kits 1 are required for the detection of different strains. Therefore, when detecting vaccinia virus strains, it is necessary to select three sets of detection kits 1 in advance. In this invention, by utilizing the cooperation between the alignment component and the plug-in component, detection kits 1 with different detection effects can be assembled and spliced ​​together. When the vaccinia virus strain is detected next time, the three sets of detection kits 1 required for detection can be obtained at one time, without having to search for the detection kits 1 one by one, thereby saving time for virus detection.

[0035] Specifically, when assembling the two sets of detection boxes 1, the alignment block 201 of one set of detection boxes 1 is aligned with the slot 301 of the other set of detection boxes 1. Then, the two sets of detection boxes 1 are pushed to slide against each other until they can no longer be pushed. At this point, the positioning mechanism inside the detection box 1 is activated to lock the two sets of detection boxes 1 together, so that the two sets of detection boxes 1 can be fixed together, thus facilitating subsequent use.

[0036] Please see Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 6 , Figure 7 The detection box 1 is also provided with a positioning mechanism, which includes a trigger component and a locking component. The trigger component includes a trigger plate 5 disposed on the U-shaped part 2, and the locking component includes a locking member slidably disposed on the detection box 1. When the two sets of detection boxes 1 are assembled and connected, one set of detection boxes 1 can push the trigger plate 5 to slide relative to the detection box 1, thereby driving the locking component to move so that the locking member slides relative to the detection box 1, thereby locking the connection state of the two sets of detection boxes 1.

[0037] The triggering component also includes a movable plate 6, which is slidably connected to a guide rod 7 disposed in the detection box 1. The guide rod 7 is provided in two sets, and a second spring 15 is slidably disposed on each set of the guide rod 7. One end of the second spring 15 abuts against the detection box 1, and the other end abuts against the movable plate 6.

[0038] The movable plate 6 is also provided with a fitting groove, and a slide rod 501 fixedly connected to the trigger plate 5 is slidably disposed in the fitting groove. When the trigger plate 5 slides, the slide rod 501 cooperates with the fitting groove to drive the movable plate 6 to slide along the width direction of the detection box 1.

[0039] Please see Figure 3 , Figure 4 , Figure 5The aforementioned fitting groove includes an inclined groove 602, with a first vertical groove 601 and a second vertical groove 603 connected to its two ends respectively. The guide rod 7 is arranged along the length of the detection box 1, and the second spring 15 is always in a compressed state. In this compressed state, the second spring 15 can push the moving plate 6 towards the trigger plate 5. Initially, the sliding rod 501 is located at the end of the stroke of the first vertical groove 601 away from the inclined groove 602. At this time, the moving plate 6 is close to the trigger plate 5, and the trigger plate 5 is away from the bottom of the U-shaped part 2 (e.g., ...). Figure 1 As shown, during the assembly of the two sets of detection boxes 1, the plug-in block 3 can contact the trigger plate 5. As the detection box 1 continues to be inserted, the plug-in block 3 can push the trigger plate 5 to slide towards the bottom of the U-shaped part 2. During this process, the slide rod 501 can slide along the first vertical groove 601 until the slide rod 501 moves to contact the inclined groove 602. The contact pressure generated by the slide rod 501, which continues to move with the trigger plate 5, on the groove wall of the inclined groove 602 can force the moving plate 6 away from the trigger plate 5. After the slide rod 501 is engaged with the second vertical groove 603, the slide rod 501 can continue to slide along the second vertical groove 603 until it can no longer push the detection box 1. At this time, the slide rod 501 moves to the end of the stroke of the second vertical groove 603. Under the restriction of the second vertical groove 603, the position of the moving plate 6 is restricted. During the movement of the moving plate 6, the locking component is triggered, which can drive the locking component to move, thereby locking the position of the two sets of detection boxes 1.

[0040] For details, please refer to Figure 3 , Figure 4 , Figure 6 , Figure 7 The locking assembly includes an instantaneous structure and a trigger. The trigger includes a drive gear plate 11 fixedly connected to the moving plate 6. The drive gear plate 11 engages with a gear 12 rotatably installed in the detection box 1.

[0041] The instantaneous structure includes a stabilizing plate 9 fixedly installed inside the detection box 1. The stabilizing plate 9 is provided with an upper baffle 901 and a lower baffle 902, and a deflection plate 10 is rotatably installed on the stabilizing plate 9. The rotating shaft of the deflection plate 10 is coaxially fixed with the gear 12, and the deflection plate 10 is connected to the stabilizing plate 9 through a first spring 14.

[0042] The locking component includes a locking block 4 slidably disposed on the detection box 1, and a driven toothed plate 13 is disposed on the locking block 4, which meshes with the gear 12;

[0043] In particular, please see Figure 1 , Figure 4 , Figure 6 , Figure 7The first spring 14 is in the stretched state. In the initial state, the first spring 14 pulls the deflection plate 10 to fit against the lower baffle 902, and the locking block 4 is in the state of... Figure 1 As shown in the rightmost detection box 1, and in conjunction with the above, when the moving plate 6 moves away from the trigger plate 5, the drive gear plate 11 on the moving plate 6 can drive the gear 12 to rotate clockwise (in conjunction with...). Figure 6 At this time, the rotating gear 12 can drive the deflection plate 10 to deflect towards the upper baffle 901, and the first spring 14 is further stretched. At the same time, the gear 12 can drive the driven toothed plate 13 to drive the locking block 4 to move towards the trigger plate 5 along the width direction of the detection box 1 until the slide rod 501 moves to separate from the inclined groove 602, driving the toothed plate 11 to separate from the gear 12. At this time, the gear 12 drives the deflection plate 10 to cross the horizontal plane formed by the stabilizing plate 9 and the deflection plate 10. The locking block 4 comes to the edge of the detection box 1, and then the first spring 14 retracts, which can drive the deflection plate 10 to have an automatic tendency to deflect towards the upper baffle 901. However, since the detection box 1 is not inserted into place, the insertion block 3 is not in contact with the locking block. The contact of 4 keeps the locking block 4 at the edge of the previous set of test boxes 1 until the test box 1 is inserted into place. Then, under the action of the deflection plate 10 which automatically deflects, the locking block 4 can contact the next test box 1, thereby locking the position of the next test box 1 and completing the assembly connection between the two sets of test boxes 1. According to the actual detection needs of vaccinia virus, the test boxes 1 can be assembled arbitrarily to form a multi-component rapid test box. Compared with a single test box 1, the assembled test box 1 is larger in size and easier to find. Moreover, the multi-component rapid test box assembled according to the usage needs is easy to use, without the need to search for the required test boxes 1 one by one, making it more convenient and faster to use.

[0044] When taking out the test box 1, the locking block 4 is moved away from the trigger plate 5 while the test box 1 is pulled outward to complete the disassembly of any test box 1.

[0045] It will be apparent to those skilled in the art that this invention is not limited to the details of the exemplary embodiments described above, and that it can be implemented in other specific forms without departing from the spirit or essential characteristics of this invention. Therefore, the embodiments should be considered illustrative and non-limiting in all respects, and the scope of this invention is defined by the appended claims rather than the foregoing description. Thus, it is intended that all variations falling within the meaning and scope of equivalents of the claims be included within this invention. No reference numerals in the claims should be construed as limiting the scope of the claims.

[0046] Furthermore, it should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This narrative style is merely for clarity. Those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. A multi-component assembled rapid test kit based on a nucleic acid-protein conjugation system, characterized in that, include: The test box (1) is provided with a connecting component. The connecting component includes alignment parts and plug-in parts disposed on the left and right sides of the test box (1). With the cooperation between the alignment parts and the plug-in parts, two sets of the test boxes (1) can be assembled and connected. The detection box (1) is also provided with a positioning mechanism, which includes a trigger component and a locking component. The trigger component includes a trigger plate (5) disposed on the U-shaped part (2), and the locking component includes a locking member slidably disposed on the detection box (1). When the two sets of detection boxes (1) are assembled and connected, one set of detection boxes (1) can push the trigger plate (5) to slide relative to the detection box (1), thereby driving the locking component to move so that the locking member slides relative to the detection box (1), thereby locking the connection state of the two sets of detection boxes (1).

2. The multi-component assembled rapid test kit based on a nucleic acid-protein conjugation system according to claim 1, characterized in that, The alignment component includes a U-shaped component (2) disposed on the side of the detection box (1), and an alignment block (201) is disposed on the side wall of the U-shaped component (2).

3. The multi-component assembled rapid test kit based on a nucleic acid-protein conjugation system according to claim 2, characterized in that, The connector includes a connector block (3) disposed on the detection box (1), and the connector block (3) has a slot (301) adapted to the alignment block (201).

4. The multi-component assembled rapid test kit based on a nucleic acid-protein conjugation system according to claim 2, characterized in that, The triggering component also includes a movable plate (6), which is slidably connected to a guide rod (7) disposed in the detection box (1). The guide rod (7) is provided in two sets, and a second spring (15) is slidably disposed on each set of the guide rod (7). One end of the second spring (15) abuts against the detection box (1), and the other end abuts against the movable plate (6).

5. The multi-component assembled rapid test kit based on a nucleic acid-protein conjugation system according to claim 4, characterized in that, The movable plate (6) is also provided with a fitting groove, and a slide rod (501) fixedly connected to the trigger plate (5) is slidably arranged in the fitting groove. When the trigger plate (5) slides, the slide rod (501) cooperates with the fitting groove, which can drive the movable plate (6) to slide along the width direction of the detection box (1).

6. The multi-component assembled rapid test kit based on a nucleic acid-protein conjugation system according to claim 4, characterized in that, The locking assembly includes an instantaneous structure and a trigger. The trigger includes a drive gear plate (11) fixedly connected to the moving plate (6). The drive gear plate (11) engages with a gear (12) rotatably installed in the detection box (1).

7. The multi-component assembled rapid test kit based on a nucleic acid-protein conjugation system according to claim 6, characterized in that, The instantaneous structure includes a stabilizing plate (9) fixedly installed inside the detection box (1). The stabilizing plate (9) is provided with an upper baffle (901) and a lower baffle (902). A deflecting plate (10) is rotatably installed on the stabilizing plate (9). The rotating shaft of the deflecting plate (10) is coaxially fixed with the gear (12). The deflecting plate (10) is connected to the stabilizing plate (9) through a first spring (14).

8. The multi-component assembled rapid test kit based on a nucleic acid-protein conjugation system according to claim 7, characterized in that, The locking element includes a locking block (4) slidably disposed on the detection box (1), and a driven toothed plate (13) is disposed on the locking block (4), which meshes with the gear (12).

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