Detection sample dilution system
By implementing an automated dilution method for the test sample dilution system, the problems of complexity and low efficiency in sample dilution are solved, enabling rapid dilution and efficient testing.
Patent Information
- Application Number
- CN202422528899.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-19
- Publication Date
- 2025-12-26
- Estimated Expiration
- 2034-10-19
AI Technical Summary
Existing sample dilution methods are complex and inefficient. Manual dilution is prone to introducing errors, and dilution for specific instruments increases intermediate processes and workload, reducing the consistency and efficiency of detection.
The test sample dilution system, consisting of components such as reaction cups, pumps, sampling needles, and solenoid valves, achieves rapid dilution of sample solutions through automated control. The dilution factor is flexibly adjustable, reducing manual intervention.
It enables rapid dilution of sample solutions, with flexible and adjustable dilution ratios, reducing costs, improving testing efficiency, simplifying processes, and reducing manpower and instrument costs.
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Figure CN223727506U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to medical detection technical field, specifically, and particularly relates to a detection sample dilution system and automatic dilution machine. BACKGROUND
[0002] In the prior art, in the field of in-vitro diagnostic analysis instrument and equipment, when the sample and reagent react, the sample concentration participating in the reaction needs to be within a certain range according to the requirements of the related reagent, so as to obtain reliable detection results. In clinical examination, the sample concentration may exceed the required range of the reagent, at which time the sample needs to be diluted and then reacted with the reagent.
[0003] At present, in the field of in-vitro diagnostic analysis instrument and equipment, the conventional method for diluting the sample includes manual dilution and specific instrument dilution. The manual dilution is a method in which the staff dilutes the sample by using a liquid dispenser and other tools for manual operation. This method is relatively complex to operate, and errors are easily introduced in the manual operation, while the human resources are wasted and the detection efficiency is low. The specific instrument dilution is a method in which the staff puts the sample into a dilution instrument for dilution, takes out the sample after the dilution is completed, and then puts the sample into a detection instrument for detection, which is equivalent to adding an intermediate process, increasing the complexity of detection, reducing the continuity and efficiency of detection, and also increasing the workload and error probability of the staff. Therefore, it is necessary to solve the problems existing in the prior art. UTILITY MODEL CONTENT
[0004] The utility model aims at solving at least one of the above technical problems in the prior art to some extent. Therefore, one purpose of the utility model is to provide a detection sample dilution system and automatic dilution machine which can realize rapid dilution of a sample solution, the dilution multiple of which is flexible and adjustable, the sample test efficiency is improved, and the sample dilution cost is also reduced.
[0005] The technical scheme for solving the above technical problem of the utility model is as follows: a detection sample dilution system comprises:
[0006] A reaction cup mixes the sample and the diluent, and fully shakes to obtain a first mixed solution; the reaction cup also discharges the remaining first mixed solution; the reaction cup mixes the first mixed solution and the diluent, and fully shakes to obtain a second mixed solution;
[0007] A first pump body also communicates with the reaction cup; the first pump body draws the diluent into the reaction cup; the first pump body also draws a certain amount of the first mixed solution in the reaction cup for temporary storage; after the reaction cup discharges the remaining first mixed solution, a certain amount of the first mixed solution is introduced into the reaction cup again; the first pump body also injects a certain amount of the diluent into the reaction cup;
[0008] A sampling needle draws a sample into the reaction cup; the sampling needle draws a certain amount of reagent into the reaction cup.
[0009] The utility model discloses beneficial effect is: in the dilution process to the sample, through the first mixed liquid part mixed liquid is drawn out, add the diluent of equal volume to the first mixed liquid to realize the quick dilution of sample solution, and its dilution multiple is flexible and adjustable, is widely used in the dilution of various high -concentration sample, promotes sample test efficiency, dilution process to the sample only needs to complete sample dilution in the reaction cup, does not need the special dilution cup, reduces sample dilution cost, also can promote the test efficiency of sample.
[0010] On the basis of the above technical scheme, the utility model still can make following improvement.
[0011] Further, it further comprises a first tank body, the first tank body stores diluent, and the input end of the first pump body is communicated with the first tank body.
[0012] Further, it further comprises a first three-way electromagnetic valve, the first port of the first three-way electromagnetic valve is communicated with the first tank body through a pipeline, the second port of the first three-way electromagnetic valve is communicated with the first pump body through a pipeline, and the third port of the first three-way electromagnetic valve is communicated with the reaction cup through a pipeline.
[0013] Further, it further comprises a second three-way electromagnetic valve arranged on the pipeline between the first three-way electromagnetic valve and the reaction cup, the first port of the second three-way electromagnetic valve is communicated with the third port of the first three-way electromagnetic valve through a pipeline, and the second port of the second three-way electromagnetic valve is communicated with the reaction cup through a pipeline.
[0014] The beneficial effect of the above further scheme is: by regulating the first pump body, the first three-way electromagnetic valve and the second three-way electromagnetic valve, automatic sample dilution is facilitated, manual intervention is reduced, and sample test efficiency is improved.
[0015] Further, it further comprises:
[0016] A second tank body, the second tank body stores cleaning liquid;
[0017] A second pump body, the input end of the second pump body is communicated with the second tank body through a pipeline, and the output end of the second pump body is communicated with the third port of the second three-way electromagnetic valve.
[0018] The beneficial effect of the above further scheme is: by regulating the second pump body and the second three-way electromagnetic valve, the reaction cup is conveniently cleaned, cleaning is facilitated, labor intensity of detection is reduced, and sample test efficiency is improved.
[0019] Further, it further comprises:
[0020] A third pump body, an input end of the third pump body being communicated with the reaction cup, the third pump body pumping out the first mixed solution remaining in the reaction cup;
[0021] A waste liquid barrel, the waste liquid barrel being communicated with an output end of the third pump body, the waste liquid barrel storing the first mixed solution pumped out by the third pump body.
[0022] The beneficial effect of the further scheme is that the reaction cup is pumped out of waste liquid by regulating the third pump body, labor intensity is reduced, and sample testing efficiency is improved.
[0023] Further, the system further comprises:
[0024] A first electromagnetic valve, the first electromagnetic valve being arranged on a pipeline between the first three-way electromagnetic valve and the second three-way electromagnetic valve, one port of the first electromagnetic valve being communicated with the third port of the first three-way electromagnetic valve through the pipeline, and the other port of the first electromagnetic valve being communicated with the first port of the second three-way electromagnetic valve through the pipeline.
[0025] A second electromagnetic valve, the second electromagnetic valve being arranged on a pipeline between the reaction cup and the third pump body, one port of the second electromagnetic valve being communicated with the reaction cup through the pipeline, and the other port of the second electromagnetic valve being communicated with the third pump body through the pipeline.
[0026] The beneficial effect of the further scheme is that the first electromagnetic valve and the second electromagnetic valve are used to facilitate sample detection and subsequent processing.
[0027] The technical scheme for solving the above technical problem is as follows: an automatic dilution machine, comprising a detection sample dilution system, a host computer and a slave computer
[0028] The host computer is used for inputting a dilution multiple required to be diluted and generating dilution information.
[0029] The slave computer is connected with the signal output end of the host computer through a signal input end, and an output end of the slave computer is connected with the detection sample dilution system; the slave computer receives the dilution information and controls the detection sample dilution system to automatically dilute the detection sample according to the dilution information.
[0030] The beneficial effect of the automatic dilution machine is that the host computer and the slave computer cooperate with the detection sample dilution system, the sample dilution process is simplified, the testing efficiency is improved, and the labor cost and other instrument cost are saved. BRIEF DESCRIPTION OF DRAWINGS
[0031] Figure 1 A schematic diagram of the detection sample dilution system of the automatic dilution machine;
[0032] Figure 2The utility model relates to an automatic dilution machine's module block diagram.
[0033] In the drawing, the component list that each sign represents is as follows:
[0034] 1, detection sample dilution system, 101, reaction cup, 102, first pump body, 103, sampling needle, 104, first jar body, 105, first three-way electromagnetic valve, 106, second three-way electromagnetic valve, 107, second jar body, 108, second pump body, 109, third pump body, 110, waste liquid barrel, 111, first electromagnetic valve, 112, second electromagnetic valve;
[0035] 2, host computer, 3, lower computer. DETAILED DESCRIPTION
[0036] The principles and characteristics of the utility model are described below in combination with the drawings, and the examples are only used to explain the utility model and are not used to limit the scope of the utility model.
[0037] As Figure 1 Shown, it is the principle diagram of detection sample dilution system of the utility model.A kind of detection sample dilution system in the utility model, including:
[0038] Reaction cup 101, the reaction cup 101 mixes sample and diluent, and is fully shaken to obtain first mixed solution;The reaction cup 101 still discharges the remaining first mixed solution;The reaction cup 101 mixes first mixed solution and diluent, and is fully shaken to obtain second mixed solution;
[0039] First pump body 102, the first pump body 102 still communicates with the reaction cup 101;The first pump body 102 extracts diluent to reaction cup 101;The first pump body 102 still extracts a certain amount of first mixed solution in reaction cup 101 and stores temporarily;The reaction cup 101 after discharging the remaining first mixed solution, a certain amount of first mixed solution is reintroduced into reaction cup 101;The first pump body 102 still injects a certain amount of diluent into reaction cup 101;
[0040] Sampling needle 103, the sampling needle 103 extracts sample and injects into reaction cup 101;The sampling needle 103 extracts a certain amount of reagent and injects into reaction cup 101.
[0041] In actual application, the first pump body 102 is a plunger pump. The first pump body 102 is used to draw the diluent into the reaction cup 101 first. The sampling needle 103 is used to draw the sample into the reaction cup 101, so that the sample is mixed with the diluent to obtain the first mixed liquid. The first pump body 102 is also used to draw a certain amount of the first mixed liquid in the reaction cup 101 for temporary storage. When the reaction cup 101 still has the first mixed liquid, the first pump body 102 is used to discharge the first mixed liquid in the reaction cup 101. After the first mixed liquid is discharged, the first pump body 102 is used to introduce a certain amount of the first mixed liquid into the reaction cup 101. Then, the first pump body 102 is used to inject a certain amount of the diluent into the reaction cup 101. The reaction cup 101 mixes the first mixed liquid and the diluent and fully shakes to obtain the second mixed liquid, so as to complete the dilution of the sample. A certain amount of reagent is injected into the reaction cup 101, and the reaction cup 101 is fully shaken to perform the test.
[0042] In the embodiment, in the process of diluting the sample, part of the first mixed liquid is drawn out first, and then an equal volume of diluent is added to the first mixed liquid, so that the sample solution is quickly diluted. The dilution multiple is flexible and adjustable, and is widely applicable to the dilution of various high-concentration samples, thereby improving the sample test efficiency. In the process of diluting the sample, only the sample needs to be diluted in the reaction cup, and a special dilution cup is not required, so that the sample dilution cost is reduced and the sample test efficiency is improved.
[0043] Further, the first tank body 104 is further provided. The first tank body 104 stores the diluent. The input end of the first pump body 102 is in communication with the first tank body 104.
[0044] The first three-way electromagnetic valve 105 is further provided. The first port of the first three-way electromagnetic valve 105 is in communication with the first tank body 104 through a pipeline. The second port of the first three-way electromagnetic valve 105 is in communication with the first pump body 102 through a pipeline. The third port of the first three-way electromagnetic valve 105 is in communication with the reaction cup 101 through a pipeline.
[0045] The second three-way electromagnetic valve 106 is further provided and arranged on the pipeline between the first three-way electromagnetic valve 105 and the reaction cup 101. The first port of the second three-way electromagnetic valve 106 is in communication with the third port of the first three-way electromagnetic valve 105 through a pipeline. The second port of the second three-way electromagnetic valve 106 is in communication with the reaction cup 101 through a pipeline.
[0046] In actual application, the first pump body 102 is in communication with the first tank body 104 and the reaction cup 101 through the first three-way electromagnetic valve 105 and the second three-way electromagnetic valve 106, respectively.
[0047] Specifically, the first port of the first three-way electromagnetic valve 105 is communicated with the second port thereof, and the first pump body 102 draws the diluent in the first tank body 104 through the first three-way electromagnetic valve 105; then the second port of the first three-way electromagnetic valve 105 is communicated with the third port thereof, and the first port and the second port of the second three-way electromagnetic valve 106 are communicated with each other, so that the diluent is delivered into the reaction cup 101 through the third port of the first three-way electromagnetic valve 105, the first port of the second three-way electromagnetic valve 106 and the second port of the second three-way electromagnetic valve 106; similarly, when the first pump body 102 extracts the first mixed liquid in the reaction cup 101, the first pump body 102 extracts the first mixed liquid in the reaction cup 101 to the pipeline between the second three-way electromagnetic valve 106 and the reaction cup 101 through the first three-way electromagnetic valve 105 and the second three-way electromagnetic valve 106 for temporary storage, and then returns the first mixed liquid in the pipeline to the reaction cup 101.
[0048] In the embodiment, the first pump body 102, the first three-way electromagnetic valve 105 and the second three-way electromagnetic valve 106 are controlled to facilitate automatic sample dilution, reduce manual intervention and improve sample test efficiency.
[0049] Further, the device further comprises:
[0050] The second tank body 107 stores cleaning liquid.
[0051] The second pump body 108 is communicated with the second tank body 107 through a pipeline, and the output end of the second pump body 108 is communicated with the third port of the second three-way electromagnetic valve 106.
[0052] In actual application, after sample test, the reaction cup 101 and other detection instruments need to be cleaned, the third port of the second three-way electromagnetic valve 106 is communicated with the first port thereof, and the second pump body 108 extracts the cleaning liquid in the second tank body 107 and delivers the cleaning liquid into the reaction cup 101 through the second three-way electromagnetic valve 106.
[0053] In the embodiment, the second pump body 108 and the second three-way electromagnetic valve 106 are controlled to facilitate cleaning of the reaction cup 101, facilitate cleaning, reduce labor intensity of detection and improve sample test efficiency.
[0054] Further, the device further comprises:
[0055] The third pump body 109 is communicated with the reaction cup 101, and the third pump body 109 extracts the remaining first mixed liquid in the reaction cup 101.
[0056] A waste liquid barrel 110 is in communication with the output end of the third pump body 109, and the waste liquid barrel 110 stores the first mixed liquid pumped out by the third pump body 109.
[0057] In actual application, the third pump body 109 pumps out the first mixed liquid remaining in the reaction cup 101 and transports the first mixed liquid to the waste liquid barrel 110. The third pump body 109 can also pump out the waste liquid generated after the reaction cup 101 is detected and cleaned to the waste liquid barrel 110.
[0058] In the embodiment, the third pump body 109 is controlled to facilitate pumping out the waste liquid of the reaction cup 101, reduce labor intensity, and improve sample testing efficiency.
[0059] Further, the detection sample dilution system further comprises:
[0060] A first electromagnetic valve 111 is arranged on the pipeline between the first three-way electromagnetic valve 105 and the second three-way electromagnetic valve 106. One port of the first electromagnetic valve 111 is in communication with the third port of the first three-way electromagnetic valve 105 through a pipeline. The other port of the first electromagnetic valve 111 is in communication with the first port of the second three-way electromagnetic valve 106 through a pipeline.
[0061] A second electromagnetic valve 112 is arranged on the pipeline between the reaction cup 101 and the third pump body 109. One port of the second electromagnetic valve 112 is in communication with the reaction cup 101 through a pipeline. The other port of the second electromagnetic valve 112 is in communication with the third pump body 109 through a pipeline.
[0062] In the embodiment, the first electromagnetic valve 111 is used to control the pipeline between the first three-way electromagnetic valve 105 and the second three-way electromagnetic valve 106 to be open or blocked. The second electromagnetic valve 112 is used to control the pipeline between the reaction cup 101 and the third pump body 109 to be open or blocked, so as to facilitate sample detection and subsequent processing.
[0063] Finally, in order to match the above-mentioned detection sample dilution system, as shown in the drawings, the utility model also provides an automatic dilution machine, which comprises a detection sample dilution system 1, an upper computer 2 and a lower computer 3. Figure 2
[0064] The upper computer 2 is used to input the dilution multiple required and generate dilution information.
[0065] The lower computer 3 is connected with the signal output end of the upper computer 2 through a signal input end. The output end of the lower computer 3 is connected with the detection sample dilution system 1. The lower computer 3 receives the dilution information and controls the detection sample dilution system 1 to automatically dilute the detection sample according to the dilution information.
[0066] In the actual application process, the lower computer 3 is electrically connected with the first pump body 102, the first three-way electromagnetic valve 105, the second three-way electromagnetic valve 106, the second pump body 108, the third pump body 109, the first electromagnetic valve 111 and the second electromagnetic valve 112 respectively, and controls the first pump body 102, the first three-way electromagnetic valve 105, the second three-way electromagnetic valve 106, the second pump body 108, the third pump body 109, the first electromagnetic valve 111 and the second electromagnetic valve 112 to operate coordinately;
[0067] Before the sample detection starts, the tester inputs the dilution multiple required in the upper computer 2, and the lower computer 3 controls the first pump body 102, the first three-way electromagnetic valve 105, the second three-way electromagnetic valve 106, the second pump body 108, the third pump body 109, the first electromagnetic valve 111 and the second electromagnetic valve 112 to operate during the dilution process, controls the amount of the first mixed liquid and the dilution liquid to be extracted, dilutes the sample according to the set dilution multiple, and completes the target dilution multiple.
[0068] The embodiment detects the sample dilution system 1 by cooperation of the upper computer 2 and the lower computer 3, simplifies the sample dilution process, improves the test efficiency, and saves the labor cost and other instrument cost.
[0069] The above only describes the preferred embodiment of the utility model, and does not limit the utility model, and any modification, equivalent replacement, improvement, etc. within the spirit and principle of the utility model should be included in the protection scope of the utility model.
Claims
1. A sample dilution system for detecting, comprising: Comprising: a reaction cup, which mixes a sample and a diluent and fully shakes to obtain a first mixed liquid; the reaction cup also discharges the remaining first mixed liquid; the reaction cup mixes the first mixed liquid and the diluent and fully shakes to obtain a second mixed liquid; a first pump body, which also communicates with the reaction cup; the first pump body extracts the diluent into the reaction cup; the first pump body also extracts a certain amount of the first mixed liquid in the reaction cup for temporary storage; after the reaction cup discharges the remaining first mixed liquid, a certain amount of the first mixed liquid is introduced into the reaction cup; the first pump body also injects a certain amount of diluent into the reaction cup; a sampling needle, which extracts the sample and injects it into the reaction cup; the sampling needle extracts a certain amount of reagent and injects it into the reaction cup.
2. The detection sample dilution system of claim 1, wherein: Further comprising a first tank body, which stores the diluent, and the input end of the first pump body communicates with the first tank body.
3. The detection sample dilution system of claim 2, wherein: Further comprising a first three-way electromagnetic valve, the first port of which communicates with the first tank body through a pipeline, the second port of which communicates with the first pump body through a pipeline, and the third port of which communicates with the reaction cup through a pipeline.
4. The detection sample dilution system of claim 3, wherein: Further comprising a second three-way electromagnetic valve arranged on the pipeline between the first three-way electromagnetic valve and the reaction cup, the first port of which communicates with the third port of the first three-way electromagnetic valve through a pipeline, and the second port of which communicates with the reaction cup through a pipeline.
5. The detection sample dilution system of claim 4, wherein: Further comprising: a second tank body, which stores a cleaning liquid; a second pump body, the input end of which communicates with the second tank body through a pipeline, and the output end of which communicates with the third port of the second three-way electromagnetic valve.
6. The detection sample dilution system of claim 5, wherein: Further comprising: a third pump body, the input end of which communicates with the reaction cup, and the third pump body extracts the remaining first mixed liquid in the reaction cup; a waste liquid barrel, which communicates with the output end of the third pump body, and stores the first mixed liquid extracted by the third pump body.
7. The detection sample dilution system of claim 6, wherein, Further comprising: a first electromagnetic valve, which is arranged on the pipeline between the first three-way electromagnetic valve and the second three-way electromagnetic valve, one port of which communicates with the third port of the first three-way electromagnetic valve through a pipeline, and the other port of which communicates with the first port of the second three-way electromagnetic valve through a pipeline; a second electromagnetic valve, which is arranged on the pipeline between the reaction cup and the third pump body, one port of which communicates with the reaction cup through a pipeline, and the other port of which communicates with the third pump body through a pipeline.