Tank body for biological reaction bag and biological reaction bag
By designing a variable aperture fixing device and a stable drainage structure, the problems of unstable fixing of the stirring shaft and poor drainage of the liquid in the bioreactor bag were solved, and the stable fixing of the stirring shaft and smooth drainage of the liquid were achieved.
Patent Information
- Application Number
- CN202423009790.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-06
- Publication Date
- 2026-01-16
- Estimated Expiration
- 2034-12-06
AI Technical Summary
In the prior art, the stirring shaft of the bioreactor bag is not ideally fixed on the flexible bioreactor bag, and it is difficult to easily disassemble and assemble with the rigid tank, resulting in instability of the stirring shaft during use.
A detachable fixing device is designed, including a through hole with a variable diameter and an adjustment device. The end of the stirring shaft is stably fixed by means of an elastic adjustment element and magnetic attraction. At the same time, a stabilizing plate and a counterweight are set to stabilize the position of the drain pipe.
This design achieves stable fixation of the stirring shaft within the bioreactor bag, facilitating assembly and disassembly, and improving the discharge efficiency of the feed liquid, thus ensuring the stability and ease of operation of the bioreactor bag.
Smart Images
Figure CN223805077U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to the field of reaction bag, especially a tank body for biological reaction bag and biological reaction bag. BACKGROUND
[0002] The stirring shaft of the disposable biological reaction bag rotates during use, in order to ensure the stability of the rotation of the stirring shaft, the two end portions of the stirring shaft need to be fixed, and under normal circumstances, one end of the stirring shaft is fixed with the driver, therefore the other end of the stirring shaft needs to be fixed.
[0003] In the prior art, the other end of the stirring shaft is directly fixed on the reaction bag, but since the reaction bag is usually of a flexible structure, the fixing effect is not ideal, and in the actual use process, the reaction bag is usually placed in a tank body, and the tank body is usually of a rigid material and can play a good fixing role, but since the reaction bag and the tank body are connected in a detachable mode, how to make the fixing device not only fix the stirring shaft well, but also make the stirring shaft and the tank body easy to disassemble and assemble has become the focus of the technical personnel in the field. SUMMARY
[0004] In order to solve the problems in the prior art, the utility model discloses a tank body for biological reaction bag and biological reaction bag.
[0005] A tank body for biological reaction bag, the biological reaction bag comprising a stirring shaft, the tank body comprising a main body for accommodating the biological reaction bag, the main body being provided with a fixing device for fixing the stirring shaft and a drainage hole for draining liquid from the biological reaction bag, the fixing device comprising a fixing member detachably connected with the main body, the fixing member being provided with a through hole, the shape of the through hole being adapted to the shape of the end portion of the stirring shaft, and the aperture of the through hole being variable.
[0006] The fixing device further comprises an adjusting device for adapting the aperture of the through hole to the diameter of the end portion of the stirring shaft at all times.
[0007] Specifically, the end portion of the stirring shaft is fixed on the main body by using the fixing member adapted to the end portion of the stirring shaft, and since the aperture of the through hole is variable and the aperture of the through hole is always adapted to the end portion of the stirring shaft by the adjusting device, the adjusting device can always fix the stirring shaft by the fixing member, which not only facilitates the disassembly and assembly between the stirring shaft and the main body, but also enables the fixing member to fix more sizes of the stirring shaft.
[0008] Preferably, the fixing member comprises a first cooperating member and a second cooperating member movably connected with each other, the aperture of the through hole is larger when the first cooperating member and the second cooperating member are away from each other, and the aperture of the through hole is smallest when the first cooperating member and the second cooperating member are attached to each other.
[0009] Specifically, the first fitting member and the second fitting member constitute the structure of the fixing member, and when they are away from each other, the aperture of the through hole becomes larger, and when they are close to each other, the aperture of the through hole becomes smaller, so that the smallest size of the stirring shaft that can be fixed is the stirring shaft whose end part is adapted to the smallest aperture of the through hole.
[0010] Preferably, the adjusting device comprises a fixed plate fixed to the main body, the fixed plate is provided with an avoiding hole for avoiding the fixing member, and the adjusting device further comprises an elastic adjusting member sleeved with at least part of the fixing member, and when the aperture of the through hole becomes larger, the elastic adjusting member is compressed.
[0011] Specifically, when the aperture of the through hole becomes larger, the elastic adjusting member is in a compressed state, that is, the elastic adjusting member always gives the fixing member an elastic force, so that the fixing member can always well fix the end part of the stirring shaft.
[0012] Preferably, the elastic adjusting member comprises a sliding block sleeved with at least part of the fixing device, and a sliding rail for sliding the sliding block, the sliding rail is fixed on the fixed plate, and the fixed plate is further provided with a stopper, and an elastic member is arranged between the stopper and the sliding block.
[0013] Specifically, when the size of the through hole becomes larger, the fixing member pushes the sliding block to slide along the sliding rail, the distance between the sliding block and the stopper becomes smaller, and the elastic member is compressed, so that the elastic member gives the sliding block an elastic force in the direction away from the stopper, which makes the first fitting member and the second fitting member close to each other, and further clamps the end part of the stirring shaft placed in the through hole, thereby achieving good fixation of the end part of the stirring shaft.
[0014] Preferably, the fixed plate is provided with a groove for accommodating the sliding block, the sliding rail and the stopper, and the shape of the groove is adapted to the shape of the sliding block.
[0015] Specifically, the groove with a shape adapted to the sliding block is arranged on the fixed plate, so that the sliding block is more stable during sliding, and the interference between the sliding block and the sliding rail due to path deviation during sliding can be significantly reduced.
[0016] Preferably, the outer side of the fixing member is provided with a clamping groove, the sliding block is clamped with the clamping groove, and the clamping groove is adapted to the shape of the sliding block.
[0017] Specifically, this structure can ensure that the sliding block always maintains a state of contact with the fixing member, so that the elastic force borne by the sliding block can be smoothly transmitted to the fixing member, and the force borne by the fixing member can also be smoothly transmitted to the sliding block.
[0018] Preferably, the first fitting member and the second fitting member are magnetically connected.
[0019] Specifically, the magnetic structure can make the first fitting part and the second fitting part receive magnetic force in addition to the elastic force of the elastic adjusting part, so that the first fitting part and the second fitting part can clamp the end part of the stirring shaft in the through hole more tightly, that is, better fix the end part of the stirring shaft.
[0020] A biological reaction bag is adapted to the tank body of any one of the preceding, and the bag body of the biological reaction bag is provided with a sealing device in sealing connection with the stirring shaft.
[0021] Specifically, since the stirring shaft needs to pass out of the biological reaction bag and be fixed on the fixing device on the tank body, it is necessary to set the sealing device to ensure the independence of the internal and external environments of the biological reaction bag.
[0022] Preferably, the liquid discharge device further comprises a liquid discharge pipe in sealing connection with the bag body and passing through the bag body and the liquid discharge hole;
[0023] The liquid discharge device further comprises a stabilizing disc for stabilizing the position of the liquid discharge pipe in the bag body, the stabilizing disc is sleeved with the liquid discharge pipe and fixed with the bag body;
[0024] The bag body is further provided with a counterweight, the counterweight is sleeved with the end part of the liquid discharge pipe, and the counterweight is used for making the end part of the liquid discharge pipe always face the bottom of the biological reaction bag.
[0025] Specifically, in the process of discharging the biological reaction bag by using the liquid discharge pipe, since there is liquid in the biological reaction bag, the buoyancy of the liquid discharge pipe in the liquid can cause the position of the liquid discharge pipe to be unstable, and thus it is difficult to discharge the liquid well, therefore, the structure of the stabilizing disc is needed to be set to stabilize the relative position between the liquid discharge pipe and the bag body, and the counterweight is used for making the end part of the liquid discharge pipe always face the bottom of the biological reaction bag, so as to ensure better liquid discharge effect.
[0026] Compared with the prior art, the utility model has the advantages that:
[0027] The structure that the fixing device is arranged at the bottom of the main body and used for fixing the stirring shaft can make the position of the stirring shaft in the biological reaction bag more stable, and the through hole of the fixing part has the structure that the hole diameter of the adjustable hole diameter adjustment device is always adjusted to make the fixing part clamp the end part of the stirring shaft, so that the fixing part can be adapted to stirring shafts of various sizes to some extent, and the stirring shaft and the fixing part can be disassembled more conveniently.
[0028] The liquid discharge device of the biological reaction bag is provided with the structure of the stabilizing disc for stabilizing the position and the counterweight for making the end part of the liquid discharge pipe always face downward, so that the liquid in the bag can be discharged more smoothly and completely. BRIEF DESCRIPTION OF DRAWINGS
[0029] Figure 1 A sectional view of the tank body for a biological reaction bag is disclosed in the utility model;
[0030] Figure 2 A Figure 1 An enlarged view of A in the middle;
[0031] Figure 3 A schematic view of the fixing device of the tank body for a biological reaction bag is disclosed in the utility model;
[0032] Figure 4 A parts view of the first matching piece of the tank body for a biological reaction bag is disclosed in the utility model;
[0033] Figure 5 A schematic view of a biological reaction bag is disclosed in the utility model;
[0034] Figure 6 A schematic view of the liquid discharge device of a biological reaction bag is disclosed in the utility model. DETAILED DESCRIPTION
[0035] The utility model will be further described below in combination with the drawings and specific embodiments.
[0036] As Figures 1-4 shown, the tank body for a biological reaction bag, the biological reaction bag comprising a stirring shaft 60, the tank body comprising a main body 10 for accommodating the biological reaction bag, the main body 10 is provided with the fixing device for fixing the stirring shaft 60 and the liquid discharge hole for the biological reaction bag to discharge liquid, the fixing device comprises the fixed piece detachably connected with the main body 10, the fixed piece is equipped with the through hole 21, the shape of the through hole 21 is adapted to the shape of the end of the stirring shaft 60, and the aperture of the through hole 21 is variable.
[0037] The fixing device further comprises an adjusting device, and the adjusting device is used to make the aperture of the through hole 21 always adapt to the diameter of the end of the stirring shaft 60.
[0038] The end of the stirring shaft 60 is fixed on the main body 10 by using the fixed piece adapted to the end of the stirring shaft 60, and since the aperture of the through hole 21 is variable and the aperture of the through hole 21 is always adapted to the end of the stirring shaft 60 by the adjusting device, that is, the adjusting device can always make the fixed piece well fix the stirring shaft 60, which not only facilitates the disassembly and assembly between the stirring shaft 60 and the main body 10, but also enables the fixed piece to fix more sizes of the stirring shaft 60.
[0039] The fixed piece comprises a first matching piece 22 and a second matching piece 23 movably connected with each other, when the first matching piece 22 and the second matching piece 23 are away from each other, the aperture of the through hole 21 is enlarged, and when the first matching piece 22 and the second matching piece 23 are attached, the aperture of the through hole 21 is minimum.
[0040] The first fitting member 22 and the second fitting member 23 constitute the structure of the fixing member, and when they are away from each other, the aperture of the through hole 21 becomes larger, and when they are close to each other, the aperture of the through hole 21 becomes smaller, so the smallest size of the stirring shaft 60 that can be fixed is the stirring shaft 60 whose end part is adapted to the smallest aperture of the through hole 21.
[0041] The adjusting device comprises a fixed plate 30 fixed to the main body 10, and the fixed plate 30 is provided with an avoiding hole for avoiding the fixing member, and the adjusting device further comprises an elastic adjusting member sleeved with at least part of the fixing member, and when the aperture of the through hole 21 becomes larger, the elastic adjusting member is compressed.
[0042] When the aperture of the through hole 21 becomes larger, the elastic adjusting member is in a compressed state, that is, the elastic adjusting member will always give the fixing member an elastic force, and the elastic force makes the fixing member always be able to well fix the end part of the stirring shaft 60.
[0043] The elastic adjusting member comprises a sliding block 41 sleeved with at least part of the fixing device, and a sliding rail 42 for sliding the sliding block 41, and the sliding rail 42 is fixed on the fixed plate 30, and the fixed plate 30 is further provided with a stopper 43, and the stopper 43 is provided with an elastic member 44 between the sliding block 41.
[0044] When the size of the through hole 21 becomes larger, the fixing member will push the sliding block 41 to slide along the sliding rail 42, the distance between the sliding block 41 and the stopper 43 becomes smaller, and the elastic member 44 is compressed, so the elastic member 44 will give the sliding block 41 an elastic force in the direction away from the stopper 43, and the elastic force makes the first fitting member 22 and the second fitting member 23 close to each other, and further clamps the end part of the stirring shaft 60 placed in the through hole 21, and realizes good fixing of the end part of the stirring shaft 60.
[0045] The fixed plate 30 is provided with a groove 31 for accommodating the sliding block 41, the sliding rail 42 and the stopper 43, and the shape of the groove 31 is adapted to the shape of the sliding block 41.
[0046] The groove 31 adapted to the shape of the sliding block 41 is arranged on the fixed plate 30, so that the sliding block 41 is more stable during sliding, and the interference between the sliding block 41 and the sliding rail 42 due to the deviation of the path during sliding can be significantly reduced.
[0047] The outer side of the fixing member is provided with a clamping groove 24, and the sliding block 41 is clamped with the clamping groove 24, and the clamping groove 24 is adapted to the shape of the sliding block 41.
[0048] This structure can ensure that the sliding block 41 always maintains a state of contact with the fixing member, so that the elastic force borne by the sliding block 41 can be smoothly transmitted to the fixing member, and the force borne by the fixing member can also be smoothly transmitted to the sliding block 41.
[0049] The first fitting member 22 is magnetically connected with the second fitting member 23.
[0050] The magnetic structure enables the first fitting member 22 and the second fitting member 23 to be connected by magnetic force in addition to the elastic force of the elastic adjusting member, so that the first fitting member 22 and the second fitting member 23 can clamp the end of the stirring shaft 60 placed in the through hole 21 more tightly, i.e. better fix the end of the stirring shaft 60.
[0051] As shown in Figures 5-6 The bag body 50 of the biological reaction bag is provided with a sealing device for sealing connection with the stirring shaft 60, which is adapted to the aforementioned tank body.
[0052] Since the stirring shaft 60 needs to pass out of the biological reaction bag and be fixed on the fixing device on the tank body, it is necessary to set the sealing device to ensure the independence of the internal and external environment of the biological reaction bag.
[0053] Further comprising a drainage device adapted to the drainage hole, the drainage device comprising a drainage pipe 51 sealingly connected with the bag body 50 and passing through the bag body 50 and the drainage hole;
[0054] Further comprising a stabilizing disc 52 for stabilizing the position of the drainage pipe 51 in the bag body 50, the stabilizing disc 52 being sleeved with the drainage pipe 51 and fixed with the bag body 50;
[0055] The bag body 50 is further provided with a counterweight 53, which is sleeved with the end of the drainage pipe 51, and the counterweight 53 is used to make the end of the drainage pipe 51 always face the bottom of the biological reaction bag.
[0056] In the process of draining the biological reaction bag by using the drainage pipe 51, due to the existence of the material liquid in the biological reaction bag, the buoyancy of the drainage pipe 51 in the material liquid will cause the position of the drainage pipe 51 to be unstable, and thus it is difficult to drain the material liquid well, so it is necessary to set the structure of the stabilizing disc 52 to ensure the stability of the relative position between the drainage pipe 51 and the bag body 50, and use the counterweight 53 to make the end of the drainage pipe 51 always face the bottom of the biological reaction bag, so as to ensure better drainage effect.
Claims
1. A tank for a bioreactor bag including a stirring shaft, the tank comprising a main body for accommodating the bioreactor bag, the main body being provided with a fixing device for fixing the stirring shaft and a drain hole for draining the bioreactor bag, characterized in that, The fixing device comprises a fixing member detachably connected with the main body, the fixing member is provided with a through hole, the shape of the through hole is matched with the shape of the end of the stirring shaft, and the aperture of the through hole is variable; The fixing device further comprises an adjusting device, which is used for matching the aperture of the through hole with the diameter of the end of the stirring shaft.
2. The tank for a bioreactor bag of claim 1, wherein, The fixing member comprises a first matching member and a second matching member movably connected with each other, when the first matching member and the second matching member are away from each other, the aperture of the through hole is enlarged, and when the first matching member and the second matching member are close to each other, the aperture of the through hole is smallest.
3. The tank for a bioreactor bag of claim 2, wherein, The adjusting device comprises a fixing plate fixed with the main body, the fixing plate is provided with an avoiding hole for avoiding the fixing member, and the adjusting device further comprises an elastic adjusting member sleeved with at least part of the fixing member, when the aperture of the through hole is enlarged, the elastic adjusting member is compressed.
4. The tank for a bioreactor bag of claim 3, wherein, The elastic adjusting member comprises a sliding block sleeved with at least part of the fixing device, a sliding rail for sliding of the sliding block, the sliding rail is fixed on the fixing plate, and the fixing plate is further provided with a stopper, and an elastic member is arranged between the stopper and the sliding block.
5. The tank for a bioreactor bag of claim 4, wherein, The fixing plate is provided with a groove for accommodating the sliding block, the sliding rail and the stopper, and the shape of the groove is matched with the shape of the sliding block.
6. The tank for a bioreactor bag of claim 4, wherein, The outer side of the fixing member is provided with a clamping groove, the sliding block is clamped with the clamping groove, and the clamping groove is matched with the shape of the sliding block.
7. The tank for a bio-reactor bag of claim 2, wherein, The first matching member and the second matching member are magnetically connected.
8. A bioreactor bag adapted to the tank of any one of claims 1-7, characterized in that, The bag body of the biological reaction bag is provided with a sealing device sealingly connected with the stirring shaft.
9. The bioreactor bag of claim 8, wherein, Further comprising a drainage device matched with the drainage hole, the drainage device comprises a drainage pipe sealingly connected with the bag body and penetrating through the bag body and the drainage hole; Further comprising a stabilizing disc for stabilizing the position of the drainage pipe in the bag body, the stabilizing disc is sleeved with the drainage pipe and fixed with the bag body.
10. The bioreactor bag of claim 9, wherein, The bag body is further provided with a counterweight, the counterweight is sleeved with the end of the drainage pipe, and the counterweight is used for making the end of the drainage pipe always face the bottom of the biological reaction bag.