Multifunctional material tray for in-situ vacuum freeze dryer

Abstract

The utility model discloses a multifunctional material tray for an in-situ vacuum freeze dryer, which comprises a plurality of mutually independent subareas, and a plurality of corresponding slots are respectively arranged on two side edges of each subarea; the two ends of each inserting plate are inserted into the corresponding inserting grooves respectively. The penicillin bottle fixing device is exquisite in structure and convenient to use, not only can ensure the stability of penicillin bottles in the test process, but also can meet the requirements of industrial large-scale production, and has extremely high universality.

Description

Technical Field

[0001] This utility model relates to experimental equipment for biopharmaceuticals, and in particular to a multifunctional material tray for in-situ vacuum freeze dryers. Background Technology

[0002] In the existing technology, the three most commonly used vials in the biopharmaceutical industry are 22mm, 16mm and 12mm in diameter. The industry generally places the vials in a rectangular stainless steel material tray for sublimation drying.

[0003] In actual research and development, users often place very few samples in the freeze-drying process, sometimes only a few to dozens of vials, and the specifications are often different, or even only one vial (the sample volume of a single vial is 5 to 10 ml). These few vials cannot fill the material tray. During the sublimation process, the vibration of the freeze dryer itself can cause the vials to shift and run away, or even tip over.

[0004] When users are exploring freeze-drying processes, their samples are often small in quantity and extremely valuable. Sometimes, obtaining 20ml of freeze-dried mixture requires dozens of process steps and takes one to two months. Therefore, if vial displacement or tipping occurs during sublimation, it can lead to irreversible failure, potentially causing the entire R&D project to fail, resulting in lost commercial opportunities and extremely high costs. Utility Model Content

[0005] According to an embodiment of the present invention, a multifunctional material tray for an in-situ vacuum freeze dryer is provided, comprising:

[0006] Several independent partitions, each with several corresponding slots on both sides;

[0007] Several insert plates, each insert plate having its two ends inserted into corresponding slots.

[0008] Furthermore, the spacing of the slots on the side of each partition corresponds to a certain diameter specification of a vial.

[0009] Furthermore, the slots on the sides of each partition are spaced the same.

[0010] Furthermore, the spacing between the slots on the sides of each partition is different.

[0011] Furthermore, the spacing specifications of the slots on the partition side include: 12mm, 16mm, and 22mm.

[0012] Furthermore, each partition has an injection port on its side, through which vials enter the corresponding partition.

[0013] Furthermore, it also includes several guide plates, which are set outside the multi-functional material tray and are connected to the injection port.

[0014] Furthermore, the bottom plate of the multi-functional material tray has a pull-out structure, which can be directly removed from the multi-functional material tray.

[0015] The multifunctional material tray for an in-situ vacuum freeze dryer according to the present invention has a compact structure and is easy to use. It can not only ensure the stability of vials during the experiment, but also adapt to the needs of large-scale industrial production and has strong versatility.

[0016] It should be understood that both the foregoing general description and the following detailed description are exemplary and intended to provide further illustration of the claimed technology. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the structure of a multifunctional material tray for an in-situ vacuum freeze dryer according to an embodiment of the present invention;

[0018] Figure 2 This is a schematic diagram of a multi-functional material tray with a guide plate for use in an in-situ vacuum freeze dryer according to an embodiment of the present invention. Detailed Implementation

[0019] The preferred embodiments of the present invention will be described in detail below with reference to the accompanying drawings, further illustrating the present invention.

[0020] First, combine Figures 1-2 The present invention describes a multifunctional material tray for an in-situ vacuum freeze dryer, which is used to hold vials and has a wide range of applications.

[0021] like Figures 1-2 As shown in the figure, the multifunctional material tray for an in-situ vacuum freeze dryer of this utility model embodiment has several independent partitions 1 and several insert plates 2. Each partition 1 has several corresponding slots 11 on both sides, and the two ends of each insert plate 2 are inserted into the corresponding slots 11. Furthermore, in this embodiment, the bottom plate 5 of the multifunctional material tray has a pull-out structure, which can be directly removed from the multifunctional material tray, so that the bottom of the vial 3 can directly contact the freeze dryer plate, thus making the heat conduction more direct and minimizing energy loss.

[0022] Furthermore, the multifunctional material tray can be made in any shape according to the needs of the in-situ vacuum freeze dryer. In this embodiment, the multifunctional material tray is rectangular as an example, and it is divided into multiple adjacent partitions 1. Each partition has several corresponding slots 11 on both sides. Different partitions can use different slot 11 spacings to match vials 3 of different diameters. After inserting the insert plate 2 into the slot 11, the vials 3 in each row are separated.

[0023] Specifically, such as Figures 1-2 As shown, the spacing of the slots 11 on the side of each partition 1 corresponds to the diameter specification of a vial 3. Furthermore, the spacing of the slots 11 on the side of each partition 1 is the same.

[0024] Furthermore, such as Figures 1-2 As shown, if the diameter of the vials 3 corresponding to each partition is different, then the spacing of the slots 11 on the side of each partition 1 will also be different.

[0025] Specifically, such as Figures 1-2 As shown, since the commonly used vials have diameters of 12mm, 16mm and 22mm, the spacing of the slots 11 on the side of partition 1 includes 12mm, 16mm and 22mm to ensure the adaptability of the material tray.

[0026] Specifically, such as Figures 1-2 As shown, each partition 1 has an inlet 12 on its side, and the vial 3 enters the corresponding partition 1 through the inlet 12.

[0027] Furthermore, such as Figure 2 As shown, each partition 1 has a guide plate 4 connected to the outside of the injection port 12. The guide plate 4 is set outside the multi-functional material tray and is connected to the injection port 12. This can realize the injection buffer of the vial 3 and improve the versatility of the multi-functional material tray.

[0028] During operation, vials 3 of various sizes enter through the inlet 12 of their corresponding section 1 and are arranged in rows. Insert plates 2 separate and fix the rows, ensuring the stability of the vials 3 during testing. Simultaneously, the entire multi-functional material tray can also be used with an automatic filling machine. Vials 3 of different sizes, after being output from the automatic filling machine, enter the inlet 12 through their corresponding guide plates 4, greatly improving the placement and injection efficiency of the vials 3, adapting to large-scale production, and possessing strong versatility.

[0029] Above, refer to Figures 1-2 This invention describes a multifunctional material tray for an in-situ vacuum freeze dryer according to an embodiment of the present invention. It has a compact structure and is easy to use. It can not only ensure the stability of vials during the experiment, but also meet the needs of large-scale industrial production and has strong versatility.

[0030] It should be noted that, in this specification, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus. Unless otherwise specified, an element defined by the phrase "comprising..." does not exclude the presence of additional identical elements in the process, method, article, or apparatus that includes that element.

[0031] Although the present invention has been described in detail through the above preferred embodiments, it should be understood that the above description should not be considered as a limitation of the present invention. Various modifications and substitutions to the present invention will be apparent to those skilled in the art after reading the above content. Therefore, the scope of protection of the present invention should be defined by the appended claims.

Claims

1. A multifunctional material tray for an in-situ vacuum freeze dryer, characterized in that, Include: Several independent partitions, each of which has several corresponding slots on both sides; Several insert plates, each insert plate having its two ends inserted into a corresponding slot; The spacing of the slots on the side of each partition corresponds to a certain diameter specification of a vial; The spacing of the slots is the same within the same partition, but different between different partitions; The spacing of the slots is 12mm, 16mm, or 22mm. Each of the partitions has an inlet on its side, through which vials enter the corresponding partition.

2. The multifunctional material tray for an in-situ vacuum freeze dryer as described in claim 1, characterized in that, It also includes several guide plates, which are disposed outside the multifunctional material tray and are connected to the injection port.

3. The multifunctional material tray for an in-situ vacuum freeze dryer as described in claim 1, characterized in that, The bottom plate of the multi-functional material tray has a pull-out structure, which can be directly removed from the multi-functional material tray.

Images