Cell screening device
By employing a spring telescopic rod and a squeezing block design in the cell screening device, the stability problem when test tubes are of different lengths is solved, achieving stable fixation of the test tubes and improving the stability and efficiency of screening.
Patent Information
- Application Number
- CN202520422206.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-12
- Publication Date
- 2026-02-10
- Estimated Expiration
- 2035-03-12
AI Technical Summary
Existing cell screening devices are difficult to stabilize when the test tubes are of different lengths, causing the test tubes to shake or tip over, which affects the screening effect.
A cell screening device was designed. By setting a spring telescopic rod and a squeezing block on the fixed plate, the spring push-pull action makes the fixed rod enter the fixed hole to stabilize the test tube. The device is guided by the guide groove and guide rod to reduce test tube shaking and displacement.
It achieves stable fixation of test tubes of different lengths, reduces test tube shaking and displacement, and improves the stability and efficiency of screening.
Smart Images
Figure CN223892733U_ABST
Abstract
Description
Technical Field
[0001] This invention belongs to the field of cell screening technology, specifically a cell screening device. Background Technology
[0002] A cell screening device is a device that can screen cells that produce specific substances in large quantities, quickly and easily. Through specific technical means, the cell screening device can realize the binding reaction between specific substances on the cell surface and recognition molecules, thereby effectively screening out target cells.
[0003] Cell screening devices play a vital role in scientific research and industrial production. Selecting a suitable cell screening device will help improve experimental efficiency and accuracy, and promote the development of related fields.
[0004] Existing cell screening devices typically place cell culture medium in test tubes, then place the test tubes on a test tube rack, and finally place them into a cell screening instrument for screening. However, during long-term use and observation, it has been found that when the test tubes are too long or too short, the test tube rack can only support and fix them at the same position. This makes it difficult to fix different test tubes, and the test tubes are prone to shaking or tipping over during the cell screening process. Therefore, a cell screening device is proposed to address the above problems. Summary of the Invention
[0005] To overcome the shortcomings of existing technologies and address the problems of existing equipment, this utility model proposes a cell screening device.
[0006] The technical solution adopted by this utility model to solve its technical problem is a cell screening device, including a screening instrument body, a controller disposed on the screening instrument body, a laser screening instrument disposed on the inner side wall of the screening instrument body, a base disposed inside the screening instrument body, multiple support columns fixedly connected to the base, a fixing plate disposed on the support columns, a slot provided on the fixing plate corresponding to the support columns, multiple fixing blocks fixedly connected to the fixing plate, a pair of first spring telescopic rods fixedly connected to the fixing blocks, a pressing block fixedly connected to the end of the first spring telescopic rods, and a fixed plate fixedly connected to the fixing plate. A fixing base is provided, with a guide hole on the fixing base. A fixing rod is slidably connected in the guide hole. The fixing rod and the extrusion block are correspondingly arranged. The support column has multiple fixing holes. A protrusion is fixedly connected to the extrusion block. By fixing the extrusion block to the end of the first spring telescopic rod and slidably connecting the fixing rod to the fixing base, when the extrusion block and the fixing rod come into contact, the extrusion block pushes the fixing rod towards the support column, allowing the fixing rod to enter the fixing hole, thereby fixing the fixing plate. This reduces the difficulty in fixing different positions of the test tubes due to different test tube lengths during use.
[0007] Preferably, a pair of second spring telescopic rods are fixedly connected to the fixed base, and a connecting plate is fixedly connected to the end of the second spring telescopic rod. The connecting plate and the fixed rod are fixedly connected. By fixing the second spring telescopic rod to the fixed base and the connecting plate to the end of the second spring telescopic rod, when the squeezing block releases the squeezing of the fixed rod, the second spring telescopic rod will pull the fixed rod towards the fixed base. This allows the fixed rod to automatically reset during operation, reducing the need for manual adjustment of the fixed rod position.
[0008] Preferably, the fixing plate has a plurality of first sliding grooves, and the fixing rod is fixedly connected to a first guide rod. The first guide rod and the first sliding groove are in sliding fit. By having the first sliding groove on the fixing plate and the first guide rod fixedly connected to the fixing rod, the first sliding groove slides inside the first guide rod when the fixing rod moves, which can guide the movement direction of the fixing rod and reduce the shaking and displacement of the fixing rod during use.
[0009] Preferably, the fixed plate has a second sliding groove, and the extrusion block is fixedly connected to a second guide rod. The second sliding groove and the second guide rod are arranged correspondingly. By having a second sliding groove on the fixed plate and a second guide rod fixedly connected to the extrusion block, the second sliding groove slides inside the second guide rod when the extrusion block moves. This can reduce the situation where the extrusion block is deviated and shaken during use, making it difficult for the extrusion block to contact the fixed rod.
[0010] Preferably, the extrusion block is provided with a guide groove, and a ball is rotatably connected to the end of the fixed rod. The guide groove and the ball are correspondingly arranged. By rotatably connecting the ball to the fixed rod and providing a guide groove on the extrusion block, the ball rolls inside the guide groove when the extrusion block moves, which enables the fixed rod to slide smoothly inside the guide groove and reduces the possibility of the fixed rod getting stuck when sliding on the extrusion block.
[0011] Preferably, a rubber block is fixed to the end of the fixing rod. The rubber block is made of a flexible material. By fixing the rubber block to the end of the fixing rod, the friction between the fixing rod and the fixing hole can be increased when the rubber block contacts the inner wall of the fixing hole, thereby reducing the shaking of the fixing rod due to insufficient friction during use.
[0012] The advantages of this utility model are:
[0013] This invention provides a cell screening device. A squeezing block is fixedly connected to the end of a first spring telescopic rod, and a fixing rod is slidably connected to a fixing base. When the squeezing block and the fixing rod come into contact, the squeezing block pushes the fixing rod toward the support column, allowing the fixing rod to enter the fixing hole, thereby fixing the fixing plate. This reduces the difficulty in fixing different positions of the test tubes due to different test tube lengths during use.
[0014] This invention provides a cell screening device. A second spring telescopic rod is fixedly connected to a fixed base, and a connecting plate is fixedly connected to the end of the second spring telescopic rod. When the squeezing block releases the squeezing of the fixed rod, the second spring telescopic rod pulls the fixed rod toward the fixed base, which enables the fixed rod to automatically reset during operation and reduces the need for manual adjustment of the fixed rod position. Attached Figure Description
[0015] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.
[0016] Figure 1 This is a schematic diagram of the main body of this utility model;
[0017] Figure 2 This is a schematic diagram of the fixing plate in this utility model;
[0018] Figure 3 This is a schematic diagram of the extrusion block in this utility model;
[0019] Figure 4 This is a schematic diagram of the first sliding groove in this utility model;
[0020] Figure 5 This is a schematic diagram of the ball bearing in this utility model;
[0021] In the diagram: 1. Screening instrument body; 11. Controller; 12. Laser screening instrument; 13. Base; 14. Support column; 15. Fixing plate; 16. Slot; 17. Fixing block; 18. First spring telescopic rod; 19. Extrusion block; 110. Fixing seat; 111. Guide hole; 112. Fixing rod; 113. Fixing hole; 114. Protrusion; 2. Second spring telescopic rod; 21. Connecting plate; 3. First slide groove; 31. First guide rod; 4. Second slide groove; 41. Second guide rod; 5. Guide groove; 51. Ball bearing; 6. Rubber block. Detailed Implementation
[0022] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of the present utility model.
[0023] Please see Figures 1-5 As shown, a cell screening device includes a screening instrument body 1 (model BDFACSDiscover™ S8 cell sorter), a controller 11 mounted on the screening instrument body 1, a laser screening instrument 12 (model Easy-Laser XT22) mounted on the inner wall of the screening instrument body 1, a base 13 inside the screening instrument body 1, multiple support columns 14 fixedly connected to the base 13, a fixing plate 15 mounted on the support columns 14, a slot 16 formed on the fixing plate 15 corresponding to the support columns 14, multiple fixing blocks 17 fixedly connected to the fixing plate 15, a pair of first spring telescopic rods 18 fixedly connected to the fixing blocks 17, a pressing block 19 fixedly connected to the end of the first spring telescopic rods 18, and a fixing seat 110 fixedly connected to the fixing plate 15. The support column 14 has a guide hole 111, and a fixing rod 112 is slidably connected inside the guide hole 111. The fixing rod 112 and the squeezing block 19 are correspondingly arranged. The support column 14 has multiple fixing holes 113, and a protrusion 114 is fixedly connected to the squeezing block 19. During use, the test tube containing cells is placed on the base 13, and then the base 13 is placed inside the screening instrument body 1. After placement, the controller 11 on the screening instrument body 1 is turned on to control the laser screening instrument 12 installed inside the screening instrument body 1 to perform the cell screening. When using the test tubes at different heights, it is necessary to fix the test tubes at different positions. At this time, the protrusion 114 fixed on the extrusion block 19 is loosened. When the protrusion 114 is loosened, the extrusion block 19 moves towards the fixing rod 112 under the action of the first spring telescopic rod 18. When the extrusion block 19 moves to the designated position, the extrusion block 19 contacts the fixing rod 112. When the fixing rod 112 moves along the edge of the extrusion block 19, the extrusion block 19 pushes the fixing rod 112 towards the support column 14. When the fixing rod 112 is pushed to the designated position, the fixing rod 112 enters the fixed position. Inside the hole 113, the fixing rod 112 fixes the fixing plate 15. The pressing block 19 is fixed to the end of the first spring telescopic rod 18, and the fixing rod 112 is slidably connected to the fixing seat 110. When the pressing block 19 and the fixing rod 112 come into contact, the pressing block 19 pushes the fixing rod 112 toward the support column 14, so that the fixing rod 112 can enter the fixing hole 113, thereby fixing the fixing plate 15. This can reduce the difficulty of fixing the test tubes at different positions due to different test tube lengths during use.
[0024] Please see Figure 2As shown, a pair of second spring telescopic rods 2 are fixedly connected to the fixed base 110. A connecting plate 21 is fixedly connected to the end of the second spring telescopic rod 2. The connecting plate 21 and the fixed rod 112 are fixedly connected. When it is necessary to adjust the height of the fixed plate 15, the protrusion 114 fixed to the pressing block 19 is pulled. When the protrusion 114 is pulled towards the fixed block 17, the pressing block 19 moves towards the protrusion 114. When the pressing block 19 moves, the pressing block 19 releases the pressure on the fixed rod 112. At this time, under the action of the second spring telescopic rod 2, the connecting plate 21 is pulled towards the fixed base 110. When the connecting plate 21 moves towards the fixed rod 112, the connecting plate 21 moves towards the fixed rod 112. When the fixed rod 112 moves in the 12-direction movement, it is driven to move towards the fixed seat 110. When the fixed rod 112 moves to the designated position, it exits from the fixed hole 113. At this time, the height of the fixed plate 15 can be adjusted. A second spring telescopic rod 2 is fixedly connected to the fixed seat 110, and a connecting plate 21 is fixedly connected to the end of the second spring telescopic rod 2. When the pressing block 19 releases the pressure on the fixed rod 112, the second spring telescopic rod 2 pulls the fixed rod 112 towards the fixed seat 110. This allows the fixed rod 112 to automatically reset during operation, reducing the need for manual adjustment of the position of the fixed rod 112.
[0025] Please see Figure 3 As shown, the fixing plate 15 has multiple first sliding grooves 3, and the fixing rod 112 is fixedly connected to a first guide rod 31. The first guide rod 31 and the first sliding groove 3 are in sliding fit. When the protrusion 114 is released, the pressing block 19 moves towards the fixing seat 110 to press the fixing rod 112. When the fixing rod 112 moves towards the fixing hole 113, the first sliding groove 3 slides inside the first guide rod 31. At this time, the first sliding groove 3 and the first guide rod 31 guide the movement direction of the fixing rod 112. By providing the first sliding groove 3 on the fixing plate 15 and the first guide rod 31 fixedly connected to the fixing rod 112, the first sliding groove 3 slides inside the first guide rod 31 when the fixing rod 112 moves, which can guide the movement direction of the fixing rod 112 and reduce the shaking and displacement of the fixing rod 112 during use.
[0026] Please see Figure 4 As shown, a second sliding groove 4 is provided on the fixed plate 15, and a second guide rod 41 is fixedly connected to the extrusion block 19. The second sliding groove 4 and the second guide rod 41 are correspondingly arranged. When the extrusion block 19 moves, the second sliding groove 4 slides inside the second guide rod 41. By providing a second sliding groove 4 on the fixed plate 15 and a second guide rod 41 fixedly connected to the extrusion block 19, the situation where the extrusion block 19 is difficult to contact the fixed rod 112 due to displacement and shaking during use can be reduced.
[0027] Please see Figure 5 As shown, the extrusion block 19 is provided with a guide groove 5, and a ball bearing 51 is rotatably connected to the end of the fixing rod 112. The guide groove 5 and the ball bearing 51 are correspondingly arranged. When the extrusion block 19 moves toward the fixing seat 110, the ball bearing 51 rolls in the guide groove 5. By rotatably connecting the ball bearing 51 to the fixing rod 112 and providing a guide groove 5 on the extrusion block 19, the ball bearing 51 rolls inside the guide groove 5 when the extrusion block 19 moves, which enables the fixing rod 112 to slide smoothly inside the guide groove 5 and reduces the possibility of the fixing rod 112 getting stuck when sliding on the extrusion block 19.
[0028] Please see Figure 5 As shown, a rubber block 6 is fixed to the end of the fixing rod 112. The rubber block 6 is made of flexible material. When the fixing rod 112 is pressed by the compression block 19 and moves towards the fixing hole 113, the rubber block 6 is moved along with it. When the rubber block 6 moves to the designated position, the rubber block 6 contacts the inner wall of the fixing hole 113 opened on the support column 14. By fixing the rubber block 6 to the end of the fixing rod 112, the friction between the fixing rod 112 and the fixing hole 113 can be increased when the rubber block 6 contacts the inner wall of the fixing hole 113, thereby reducing the situation where the fixing rod 112 shakes due to insufficient friction during use.
[0029] Working principle: During use, when the test tubes have different heights, it is necessary to fix them at different positions. At this time, the protrusion 114 fixed on the squeezing block 19 is loosened. When the protrusion 114 is loosened, the squeezing block 19 moves towards the fixed rod 112 under the action of the first spring telescopic rod 18. When the squeezing block 19 moves to the designated position, the squeezing block 19 contacts the fixed rod 112. When the fixed rod 112 moves along the edge of the squeezing block 19, the squeezing block 19 pushes the fixed rod 112 towards the support column 14. When pushed to the designated position, the fixing rod 112 enters the fixing hole 113, at which point the fixing rod 112 fixes the fixing plate 15. When the height of the fixing plate 15 needs to be adjusted, the protrusion 114 fixed on the pressing block 19 is pulled. When the protrusion 114 is pulled towards the fixing block 17, the pressing block 19 moves towards the protrusion 114. When the pressing block 19 moves, it releases the pressure on the fixing rod 112. At this time, under the action of the second spring telescopic rod 2, the connecting plate 21 is pushed towards the fixing seat 11. Pulling in the 0 direction, when the connecting plate 21 moves towards the fixed rod 112, the fixed rod 112 is driven to move towards the fixed seat 110. When the fixed rod 112 moves to the designated position, it retracts from the fixed hole 113. At this time, the height of the fixed plate 15 can be adjusted. When the protrusion 114 is released, the pressing block 19 moves towards the fixed seat 110 to press the fixed rod 112. When the fixed rod 112 moves towards the fixed hole 113, the first slide groove 3 slides inside the first guide rod 31. At this time, the first slide groove 3 and the first guide rod 31 guide the movement direction of the fixed rod 112. When the extrusion block 19 moves, the second slide groove 4 slides inside the second guide rod 41. When the extrusion block 19 moves towards the fixed seat 110, the ball 51 rolls in the guide groove 5. When the fixed rod 112 is extruded by the extrusion block 19 and moves towards the fixed hole 113, the rubber block 6 is carried along and moves with it. When the rubber block 6 moves to the designated position, the rubber block 6 contacts the inner wall of the fixed hole 113 opened on the support column 14.
[0030] In the description of this specification, references to terms such as "an embodiment," "example," "specific example," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.
[0031] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed utility model.
Claims
1. A cell screening device, characterized in that: The system includes a screening instrument body (1), on which a controller (11) is mounted. A laser screening instrument (12) is mounted on the inner wall of the screening instrument body (1). A base (13) is mounted inside the screening instrument body (1). Multiple support columns (14) are fixedly connected to the base (13). A fixing plate (15) is mounted on the support columns (14). A slot (16) is provided on the fixing plate (15). The slot (16) and the support column (14) are correspondingly arranged. Multiple fixing blocks (17) are fixedly connected to the fixing plate (15). A pair of first spring telescopic rods (18) are fixedly connected to the fixed block (17). A pressing block (19) is fixedly connected to the end of the first spring telescopic rod (18). A fixed seat (110) is fixedly connected to the fixed plate (15). A guide hole (111) is opened on the fixed seat (110). A fixed rod (112) is slidably connected in the guide hole (111). The fixed rod (112) and the pressing block (19) are arranged correspondingly. A plurality of fixed holes (113) are opened on the support column (14). A protrusion (114) is fixedly connected to the pressing block (19).
2. The cell screening device according to claim 1, characterized in that: A pair of second spring telescopic rods (2) are fixedly connected to the fixed base (110). A connecting plate (21) is fixedly connected to the end of the second spring telescopic rod (2). The connecting plate (21) and the fixed rod (112) are in a fixed connection relationship.
3. The cell screening device according to claim 1, characterized in that: The fixing plate (15) has multiple first sliding grooves (3), and the fixing rod (112) is fixedly connected to a first guide rod (31). The first guide rod (31) and the first sliding groove (3) are in sliding fit.
4. The cell screening device according to claim 1, characterized in that: The fixed plate (15) is provided with a second sliding groove (4), and the extrusion block (19) is fixed with a second guide rod (41). The second sliding groove (4) and the second guide rod (41) are provided in a corresponding manner.
5. The cell screening device according to claim 1, characterized in that: The extrusion block (19) is provided with a guide groove (5), and the end of the fixing rod (112) is rotatably connected with a ball (51). The guide groove (5) and the ball (51) are arranged correspondingly.
6. The cell screening device according to claim 1, characterized in that: A rubber block (6) is fixed to the end of the fixing rod (112), and the rubber block (6) is made of flexible material.