Filtering structure of stem cell collector

Abstract

The filtering structure of the stem cell collector comprises a lower outer cylinder, a connecting sleeve is fixed to the top of the outer side of the lower outer cylinder in an embedded mode, the inner side of the connecting sleeve is connected with the bottom of the outer side of an upper outer cylinder, a pull rod is movably installed in the upper outer cylinder, and a piston is fixed to the lower end of the pull rod in an embedded mode. According to the filtering structure of the stem cell collector, by arranging three layers of inclined filtering membranes with different pore diameters, collected sample liquid can be efficiently filtered in a multi-layer mode, impurities with different particle diameters are effectively removed, and the purity of stem cell samples is improved; through the threaded connection mode of the connecting sleeve and the upper outer cylinder and the convenient disassembly structure designed for the second filter membrane, cleaning of the interior of the device and replacement of the filter structure become simple and convenient, the maintenance cost and difficulty are reduced, particularly, the second filter membrane in the middle can be rapidly disassembled and cleaned, and the use efficiency of the equipment is improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to stem cell collection technical field, concretely is a kind of filter structure of stem cell collector. BACKGROUND

[0002] In the stem cell collection process, in order to obtain pure stem cell sample, the mixed liquid collected needs to be effectively filtered to remove impurities, cell fragments and other substances. At present, the existing stem cell collector filter structure on the market has many drawbacks. On the one hand, some filter structures only use a single filter layer, which is difficult to separate impurities of different particle sizes, resulting in low purity of the collected stem cell sample, affecting the accuracy and effectiveness of subsequent experiments and treatment. On the other hand, in terms of structural design, most filter structures have tightly fixed filter components, especially the filter component in the middle position, which is very difficult to disassemble. For example, in a common multi-layer filter structure, the second filter membrane in the middle is wrapped by other components above and below. When cleaning or replacing the second filter membrane that is clogged due to long-term use, a large number of surrounding components need to be removed, making the operation process complicated and time-consuming. In addition, it is easy to damage other components during frequent disassembly, increasing maintenance costs and equipment wear and tear.

[0003] In view of the above problems, it is necessary to make innovative design on the basis of the original stem cell collector filter structure. CONTENT OF THE UTILITY MODEL

[0004] The utility model aims to provide a kind of filter structure of stem cell collector to solve the problems raised in the above background technology.

[0005] To achieve the above purpose, the utility model provides the following technical scheme: a kind of filter structure of stem cell collector, including lower outer tube, the top of the lower outer tube outside is nested and fixed with connecting sleeve, the inner side of the connecting sleeve is connected with the bottom of the upper outer tube outside, the inside of the upper outer tube is movably installed with pull rod, the lower end of the pull rod is nested and fixed with piston, the outer side of the piston is in mutual resistance with the inner side of the upper outer tube, the bottom of the lower outer tube is provided with mouth, the inside of the lower outer tube is movably installed with first hollow support block, first ring body, second hollow support block, second ring body, third hollow support block, third ring body and fourth hollow support block from bottom to top, the inside of the first ring body is fixed with first filter membrane, the inside of the second ring body is fixed with second filter membrane, the inside of the third ring body is fixed with third filter membrane, the top of the fourth hollow support block is matched with limit ring, the outer side of the limit ring is fixedly connected with the bottom in the upper outer tube.

[0006] Preferably, the top of the lower outer cylinder is fixed with a rubber sealing ring, the top of the rubber sealing ring abuts against the bottom of the upper outer cylinder, thereby ensuring the sealing of the device during the collection process, preventing sample liquid from leaking and external impurities from entering.

[0007] Preferably, the inner side of the connecting sleeve is threadedly connected with the bottom of the outer side of the upper outer cylinder, which facilitates disassembly and installation, and facilitates cleaning and maintenance of the interior of the device.

[0008] Preferably, the top of the limiting ring abuts against the bottom of the piston, the limiting ring limits the descending position of the piston, prevents the piston from descending excessively and damaging the filtering structure, and ensures the stable operation of the filtering structure.

[0009] Preferably, the first hollow support block, the first ring body, the second hollow support block, the second ring body, the third hollow support block, the third ring body and the fourth hollow support block are combined into a hollow cylindrical structure, thereby providing stable support for the filtering membrane and ensuring the smooth progress of the filtering process.

[0010] Preferably, the first filtering membrane, the second filtering membrane and the third filtering membrane are all designed to be inclined, the filtering hole diameter on the first filtering membrane is larger than that on the second filtering membrane, and the filtering hole diameter on the second filtering membrane is larger than that on the third filtering membrane, which enables impurities of different particle sizes to be effectively intercepted on different levels of filtering membranes, improves the filtering effect, increases the filtering area, and reduces the probability of the filtering membrane being blocked.

[0011] Compared with the prior art, the stem cell collector has the following beneficial effects: the filtering structure of the stem cell collector is provided with three layers of filtering membranes with different hole diameters and inclined to the horizontal plane, can perform multi-level and efficient filtering on the collected sample liquid, effectively removes impurities of different particle sizes, and improves the purity of the stem cell sample; the threaded connection between the connecting sleeve and the upper outer cylinder and the convenient disassembly structure designed for the second filtering membrane make the cleaning of the interior of the device and the replacement of the filtering structure simple and convenient, reduce the maintenance cost and difficulty, and in particular, the second filtering membrane at the middle position can be quickly disassembled and cleaned, improving the use efficiency of the equipment; the rubber sealing ring effectively ensures the sealing of the device during the collection process, prevents sample pollution, and ensures the quality of the collected stem cell sample; the limiting effect of the limiting ring on the piston and the hollow cylindrical structure formed by the components of the filtering structure ensure the stability of the device during the operation process, and prolong the service life of the device. BRIEF DESCRIPTION OF DRAWINGS

[0012] Figure 1 It is a front view of the sectional structure of the utility model;

[0013] Figure 2 It is an overall exploded structure of the utility model.

[0014] Figure 3 It is partial explosion structure schematic view of the utility model;

[0015] Figure 4 It is upper outer tube overhead section installation structure schematic view of the utility model;

[0016] Figure 5 It is limiting ring overhead section installation structure schematic view of the utility model;

[0017] Figure 6 It is piston overhead section installation structure schematic view of the utility model.

[0018] In the drawing: 1, lower outer tube;2, connecting sleeve;3, upper outer tube;4, pull rod;5, piston;6, material port;7, first hollow support block;8, first ring body;9, first filter membrane;10, second hollow support block;11, second ring body;12, second filter membrane;13, third hollow support block;14, third ring body;15, third filter membrane;16, fourth hollow support block;17, limiting ring;18, rubber sealing ring. DETAILED DESCRIPTION

[0019] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the utility model.

[0020] Please refer to Figures 1-6 The utility model provides a kind of technical solutions: the filter structure of stem cell collector, including lower outer tube 1, the top of lower outer tube 1 outside is nested and fixed with connecting sleeve 2, the inside of connecting sleeve 2 is connected with the bottom of upper outer tube 3 outside each other, pull rod 4 is movably installed in the inside of upper outer tube 3, the lower end of pull rod 4 is nested and fixed with piston 5, the outside of piston 5 is mutually resistant with the inside of upper outer tube 3, the bottom of lower outer tube 1 is provided with material port 6, first hollow support block 7, first ring body 8, second hollow support block 10, second ring body 11, third hollow support block 13, third ring body 14 and fourth hollow support block 16 are movably installed in the inside of lower outer tube 1 from below to above in sequence, first filter membrane 9 is fixed in the inside of first ring body 8, second filter membrane 12 is fixed in the inside of second ring body 11, third filter membrane 15 is fixed in the inside of third ring body 14, the top of fourth hollow support block 16 is attached with limiting ring 17, the outside of limiting ring 17 is fixedly connected with the bottom in the inside of upper outer tube 3.

[0021] The top of the lower outer cylinder 1 is fixed with a rubber sealing ring 18, the top of which is in contact with the bottom of the upper outer cylinder 3, ensuring the sealing of the device during the collection process, preventing sample liquid leakage and external impurities from entering.

[0022] The inner side of the connecting sleeve 2 is threadedly connected with the bottom of the outer side of the upper outer cylinder 3, which facilitates disassembly and installation, and facilitates cleaning and maintenance of the inside of the device.

[0023] The top of the limiting ring 17 is in contact with the bottom of the piston 5, which limits the downward position of the piston through the limiting ring, prevents the piston from descending excessively and damaging the filter structure, and ensures the stable operation of the filter structure.

[0024] The first hollow support block 7, the first ring body 8, the second hollow support block 10, the second ring body 11, the third hollow support block 13, the third ring body 14 and the fourth hollow support block 16 are combined into a hollow cylindrical structure, which provides stable support for the filter membrane and ensures the smooth progress of the filtration process.

[0025] The first filter membrane 9, the second filter membrane 12 and the third filter membrane 15 are all designed to be inclined, and the diameter of the filter holes on the first filter membrane 9 is larger than that on the second filter membrane 12, and the diameter of the filter holes on the second filter membrane 12 is larger than that on the third filter membrane 15. This design allows impurities of different particle sizes to be effectively intercepted on different levels of filter membranes, improving the filtration effect, while increasing the filtration area and reducing the probability of filter membrane blockage.

[0026] Working principle: First, check whether the lower outer cylinder 1, the upper outer cylinder 3, the connecting sleeve 2 and each filter component are intact;

[0027] Install the first hollow support block 7, the first ring body 8, the second hollow support block 10, the second ring body 11, the third hollow support block 13, the third ring body 14 and the fourth hollow support block 16 in the lower outer cylinder 1 in order;

[0028] Tightly connect the bottom of the outer side of the upper outer cylinder 3 with the inner side of the connecting sleeve 2 through threads, and make the rubber sealing ring 18 at the top of the lower outer cylinder 1 tightly contact with the bottom of the upper outer cylinder 3, to ensure the sealing of the device;

[0029] Install the pull rod 4 in the upper outer cylinder 3, ensure that the piston 5 tightly contacts with the inner side of the upper outer cylinder 3, and can move up and down;

[0030] Align the material port 6 with the sample source that needs to collect stem cells, such as biological tissue culture liquid containing stem cells, etc.

[0031] The operator slowly pulls up the pull rod 4, and the pull rod 4 drives the piston 5 to move upward. Since the piston 5 is in close contact with the inner side of the upper outer cylinder 3, a negative pressure is gradually formed in the upper outer cylinder 3. Under the action of the negative pressure, the sample liquid enters the lower outer cylinder 1 from the material port 6. The sample first contacts the first filter membrane 9. Larger impurities such as cell clumps and tissue fragments are intercepted by the first filter membrane 9. The liquid filtered by the first filter membrane 9 continues to rise and reaches the second filter membrane 12. At this time, smaller impurities such as larger cell fragments and protein aggregates are intercepted by the second filter membrane 12. The liquid filtered twice then contacts the third filter membrane 15. Smaller impurities such as tiny cell fragments and residual culture medium impurities are intercepted by the third filter membrane 15. After three layers of filtration, the relatively pure liquid containing stem cells passes through the third filter membrane 15 and continues to rise into the upper outer cylinder 3.

[0032] If subsequent processing of the collected sample is required, the upper outer cylinder 3 can be carefully detached from the lower outer cylinder 1, and the sample liquid containing stem cells is taken out.

[0033] If the filter structure needs to be cleaned or replaced, the connecting sleeve 2 is rotated to separate the connecting sleeve 2 from the upper outer cylinder 3, and the upper outer cylinder 3 is separated from the lower outer cylinder 1. Then, the fourth hollow support block 16, the third ring body 14, and the third hollow support block 13 are taken out in turn. Then, the second ring body 11 together with the second filter membrane 12 can be conveniently taken off from the second hollow support block 10 for cleaning or replacement operation. After cleaning or replacement is completed, the components are reinstalled in reverse order for next use.

[0034] Although the utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions recorded in the foregoing embodiments or make equivalent replacement to part of the technical features. Any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the utility model shall be included in the protection scope of the utility model.

Claims

1. A filter structure for a stem cell collector, comprising a lower outer cylinder (1), wherein a connecting sleeve (2) is nested and fixed at the top of the outer side of the lower outer cylinder (1), the inner side of the connecting sleeve (2) is connected to the bottom of the outer side of an upper outer cylinder (3), a pull rod (4) is movably installed inside the upper outer cylinder (3), a piston (5) is nested and fixed at the lower end of the pull rod (4), the outer side of the piston (5) abuts against the inner side of the upper outer cylinder (3), and a feed inlet (6) is provided at the bottom of the lower outer cylinder (1), characterized in that: The inside of the lower outer cylinder (1) is sequentially movably provided with a first hollow support block (7), a first ring body (8), a second hollow support block (10), a second ring body (11), a third hollow support block (13), a third ring body (14) and a fourth hollow support block (16) from bottom to top, the inside of the first ring body (8) is fixedly provided with a first filter membrane (9), the inside of the second ring body (11) is fixedly provided with a second filter membrane (12), the inside of the third ring body (14) is fixedly provided with a third filter membrane (15), the top of the fourth hollow support block (16) is attached to a limiting ring (17), and the outside of the limiting ring (17) is fixedly connected with the bottom in the upper outer cylinder (3).

2. The filter structure of a stem cell collector according to claim 1, wherein: The top of the lower outer cylinder (1) is fixedly provided with a rubber sealing ring (18), and the top of the rubber sealing ring (18) abuts against the bottom of the upper outer cylinder (3).

3. The filter structure of claim 1, wherein: The inside of the connecting sleeve (2) is threadedly connected with the bottom of the outside of the upper outer cylinder (3).

4. The filter structure of claim 1, wherein: The top of the limiting ring (17) abuts against the bottom of the piston (5).

5. The filter structure of claim 1, wherein: The first hollow support block (7), the first ring body (8), the second hollow support block (10), the second ring body (11), the third hollow support block (13), the third ring body (14) and the fourth hollow support block (16) are combined into a hollow cylindrical structure.

6. The filter structure of claim 1, wherein: The first filter membrane (9), the second filter membrane (12) and the third filter membrane (15) are all designed to be inclined, the filter hole diameter on the first filter membrane (9) is larger than the filter hole diameter on the second filter membrane (12), and the filter hole diameter on the second filter membrane (12) is larger than the filter hole diameter on the third filter membrane (15).

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