Puncture needle
By designing a rigid needle tube and a puncture needle with a reasonable angle, the problem of embryo transfer in cases of reproductive tract abnormalities has been solved, and a highly efficient embryo transfer process has been achieved.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-24
- Publication Date
- 2026-03-31
AI Technical Summary
Existing embryo transfer catheters cannot achieve embryo transfer when the patient's reproductive tract is abnormal, especially when the vagina or cervix is not connected to the uterine cavity, making it impossible to enter the uterine cavity through the vagina.
Design a puncture needle with a rigid needle tube. The first end face of the needle tube is inclined relative to the axis, forming a first included angle of 15° to 20°. Two bevels are provided at the needle tip to reduce deformation and improve puncture efficiency during puncture.
With its rigid needle tube and reasonable angle design, the puncture needle can effectively penetrate living organisms, such as through the abdominal skin or vagina, to enter the uterine cavity for embryo transfer, thus improving puncture efficiency.
Smart Images
Figure CN224056054U_ABST
Abstract
Description
Technical Field
[0001] This application relates to the field of embryo transfer technology, and more particularly to a puncture needle. Background Technology
[0002] Embryo transfer, also known as fertilized egg transfer, refers to the technique of transferring an early embryo from a female animal, or an embryo obtained through in vitro fertilization or other methods, into another female animal of the same species and with the same physiological condition, so that it can continue to develop into a new individual.
[0003] Currently, when the patient's reproductive tract is normal, the conventional method of embryo transfer is to transfer the embryo into the uterine cavity through the vagina and cervix via an abdominal ultrasound probe under the guidance of an abdominal ultrasound probe.
[0004] However, when the patient's reproductive tract is abnormal, that is, the vagina or cervix is not connected to the uterine cavity, the embryo transfer tube cannot be inserted into the uterine cavity through the vagina. In other words, the existing embryo transfer tube can be used to transfer the embryo through the vagina. Utility Model Content
[0005] Embodiments of this application provide a puncture needle to address the problem in related technologies where embryo transfer tubes cannot achieve embryo transfer when the patient's reproductive tract is abnormal.
[0006] This application provides a puncture needle for embryo transfer. The puncture needle includes a needle tube, which is a rigid tube. A first end face of one end of the needle tube along its length is inclined relative to the axis of the needle tube to form a needle tip, which is used to enter a living organism. The first included angle between the first end face and the axis of the needle tube is 15° to 20°.
[0007] In some embodiments, the first included angle is 17°.
[0008] In some embodiments, the needle tip is provided with two inclined surfaces that intersect with the first end face; the two inclined surfaces intersect at the tip of the needle tip to form an included angle.
[0009] In some embodiments, the included angle is 40° to 70°.
[0010] In some embodiments, the included angle is 50°.
[0011] In some embodiments, the length of the needle tube is 165mm to 195mm, and the outer diameter of the needle tube is 2mm.
[0012] In some embodiments, the end of the needle tube away from the needle tip is a connecting end, and the connecting end is provided with a sleeve, which is connected to the outside of the needle tube.
[0013] In some embodiments, the cannula includes a first tube segment and a second tube segment, the first tube segment being connected to the needle tube; the inner diameter of the second tube segment is greater than or equal to the inner diameter of the first tube segment, and / or the length of the first tube segment is less than or equal to the length of the second tube segment.
[0014] In some embodiments, the sleeve is provided with an anti-slip structure.
[0015] In some embodiments, the outer wall of the connecting end is threaded, and the sleeve is screwed to the needle tube through the thread.
[0016] In some embodiments, the device further includes a die that extends from the second end into the central hole of the needle tube and extends from the port of the needle tip.
[0017] The puncture needle provided in this application embodiment forms a needle tip by tilting the first end face of the needle tube relative to the axis of the needle tube. It uses a rigid tube needle tube. At the same time, by reasonably selecting the first included angle between the first end face and the axis of the needle tube, the first included angle satisfies the above-mentioned range. In this way, during the needle tip puncture process, not only is the needle tube less likely to deform, thus facilitating the needle tip to pass through the living body, such as through the abdominal skin into the uterine cavity, or through the vagina into the uterine cavity, which is beneficial to the realization of embryo transfer, but also improves the puncture efficiency. Attached Figure Description
[0018] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.
[0019] Figure 1 This is a schematic diagram of the structure of the puncture needle in some embodiments of this application;
[0020] Figure 2 for Figure 1 A structural diagram of the tip of the puncture needle from one viewpoint;
[0021] Figure 3 for Figure 2 Rear view;
[0022] Figure 4 for Figure 3 The dashed AA section diagram in the image;
[0023] Figure 5 This is a schematic cross-sectional view of the assembly of a puncture needle, including a needle tube and a cannula, in some embodiments of this application;
[0024] Figure 6 for Figure 1 Assembly diagram of the puncture needle core.
[0025] Explanation of reference numerals in the attached figures:
[0026] 1. First included angle; 2. Included angle;
[0027] 10. Needle tube; 101. First end face; 102. Bevel; 103. Connecting end; 11. Needle tip; 12. Thread;
[0028] 20. Sleeve; 21. First pipe section; 22. Second pipe section;
[0029] 30. Core;
[0030] 40. Anti-slip structure. Detailed Implementation
[0031] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.
[0032] In the description of this application, it should be understood that the terms "center", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this application.
[0033] In the description of this application, it should be noted that, unless otherwise expressly specified and limited, the terms "installation", "connection" and "joining" should be interpreted broadly, for example, as fixed connection, detachable connection, or integral connection; those skilled in the art can understand the specific meaning of the above terms in this application according to the specific circumstances.
[0034] The terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Therefore, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this application, unless otherwise stated, "a plurality of" means two or more.
[0035] Embryo transfer, also known as fertilized egg transfer, refers to the technique of transferring an early embryo from a female animal, or an embryo obtained through in vitro fertilization or other methods, into another female animal of the same species and with the same physiological condition, so that it can continue to develop into a new individual.
[0036] Currently, when the patient's reproductive tract is normal, meaning the vagina, cervix, and uterine cavity are connected, the conventional embryo transfer method involves placing the embryo into the uterine cavity through a transfer catheter via the vagina and cervix under the guidance of an abdominal ultrasound probe. Conventional transfer catheters are flexible and easily deformed under external force. Therefore, a stylet is needed during transfer; that is, a stylet is placed inside the transfer catheter to support it. This stylet is also called a guidewire or catheter.
[0037] However, when the patient's reproductive tract is abnormal, that is, the vagina or cervix is not connected to the uterine cavity, the embryo transfer tube cannot be inserted into the uterine cavity through the vagina. In other words, the existing embryo transfer tube can be used to transfer the embryo through the vagina.
[0038] To address the aforementioned problems, this application provides a puncture needle.
[0039] The aforementioned puncture needle is typically a rigid tube with a sharp tip, and is an interventional radiology device. It is primarily used to puncture living organisms, such as human body parts, to collect human samples, inject drugs and gases, or serve as a channel for other instruments to enter the body. Puncture needles are mainly used in minimally invasive surgery for tissue sampling and injection therapy of various organs, including the kidneys, liver, lungs, breast, thyroid, prostate, pancreas, testes, uterus, ovaries, and the body surface. The puncture needle in the embodiments of this application can be used, but is not limited to, for embryo transfer.
[0040] like Figures 1-4 As shown, the puncture needle includes a needle tube 10, which is a rigid tube; a first end face 101 at one end of the needle tube 10 along its length is inclined relative to the axis of the needle tube 10 to form a needle tip 11, which is used to enter a living organism; the first end face 101 is inclined relative to the axis of the needle tube 10. Figure 4 The first included angle 1 between the dotted and dashed lines in the figure is 15° to 20°.
[0041] It should be noted that the first included angle 1, as determined through multiple clinical trials, can be applied to, but is not limited to, other puncture treatments for embryo transfer, provided the angle meets the requirement of 15° to 20°. Specific angles can also be 15°, 16°, 17°, 18°, 19°, or 20°, and are not specifically limited here.
[0042] The aforementioned living organism can be, but is not limited to, the human body. Specifically, when the puncture needle is used for embryo transfer, the needle 10 can be inserted through the abdominal wall into the uterine cavity under the guidance of abdominal ultrasound to achieve embryo transfer; or, under the guidance of a vaginal ultrasound probe, the needle 10 can be inserted through the vagina into the uterine cavity to achieve embryo transfer.
[0043] Compared to the flexible implantation tubes used in related technologies, the aforementioned needle tube 10 is a rigid tube. This means that the needle tube 10 mainly relies on the strength of the tube body material to support external forces, and its deformation under external forces is very small. The failure of the needle tube 10 is mainly due to the control of the tube wall strength. The needle tube 10 has the characteristics of high strength and low deformation. This makes it easy for the needle tube 10 to reach the uterine cavity well through the abdomen or vagina.
[0044] The puncture needle provided in this application embodiment forms a needle tip 11 by tilting the first end face 101 of the needle tube 10 relative to the axis of the needle tube 10. When the first included angle 1 between the first end face 101 and the axis of the needle tube 10 is small, the strength of the needle tip 11 is low, making it easy to deform under external force, which is not conducive to puncture. When the first included angle 1 between the first end face 101 and the axis of the needle tube 10 is large, the strength of the needle tip 11 is increased, but during puncture, the force-bearing area increases, making it difficult for the needle tip 11 to penetrate the skin, which is not conducive to puncture. By reasonably selecting the first included angle 1 between the first end face 101 and the axis of the needle tube 10, so that the first included angle 1 satisfies the above-mentioned range, during the puncture process of the needle tip 11, not only is the needle tube 10 less prone to deformation, thus facilitating the needle tip 11 to pass through the living body, such as entering the uterine cavity through the abdominal skin or through the vagina, which is conducive to embryo transfer, but also the puncture efficiency is improved.
[0045] like Figure 2 and Figure 3 As shown, in this embodiment, the needle tip 11 is provided with two inclined surfaces 102, which intersect with the first end face 101; the two inclined surfaces 102 intersect near the tip of the needle tip 11 to form an included angle 2. Figure 3 An angle formed at the tip of the needle 11 shown above, where the included angle 2 is 50°.
[0046] With the above-mentioned configuration, the needle tip 11 of the needle tube 10 is close to a pyramid or cone structure, which makes it easier for the needle tip 11 to puncture into the living organism from different angles, thus making puncture more convenient.
[0047] It should be noted that, based on multiple clinical trials, the angle 2 formed by the two inclined planes 102 at the tip of the needle 11 only needs to meet the requirement of 40° to 70° to be applicable to other puncture treatments for embryo transfer, but not limited to them. Specific angles can also be 40°, 41°, 42°, 48°, 49°, 52°, 60°, 65°, 66°, or 70°, and are not specifically limited here.
[0048] In the design of the needle tube 10, its outer diameter and length are also quite important. The following explanation uses an outer diameter of 2mm as an example.
[0049] The needle tube 10 has an outer diameter of 2mm, corresponding to a puncture needle size of 14G or 20. The "G" in 14G refers to the unit for puncture needles used in Europe and America; "G" is short for Gauge. Size 20 refers to the size of a puncture needle with an outer diameter of 2mm according to Chinese national standards.
[0050] like Figure 4 and Figure 5 As shown, when the outer diameter of the needle tube 10 is 2mm, the length of the needle tube 10 is ( Figure 5 In this case, L1 is 175mm, and the first included angle 1 between the first end face 101 and the axis of the needle tube 10 is 17°. At this time, the size of the inclined surface 102 of the needle tip 11 is 7.84mm.
[0051] Through multiple trials, the puncture needle, which is 175mm long and 2mm in outer diameter, has been found to be quite versatile and can be used for embryo transfer in various transfer methods.
[0052] It should be noted that, in addition to the 175mm length, the puncture needle 10 can also be designed to any length within the range of 165mm to 195mm, without specific limitations. The aforementioned length range of 165mm to 195mm was obtained through multiple clinical trials and can be applied to, but not limited to, other puncture treatments for embryo transfer. The following explanation uses a 175mm length needle 10 as an example.
[0053] In the design of the puncture needle, for ease of operation, the end of the needle tube 10 away from the needle tip 11 is usually the connecting end 103. The connecting end 103 is provided with a sleeve 20, which is connected to the outside of the needle tube 10.
[0054] It should be noted that during the use of the puncture needle, the needle tip 11 is first inserted into the uterine cavity, and then the core 30 is inserted into the uterine cavity through the needle tube 10 to achieve embryo transfer.
[0055] The aforementioned sleeve 20 is cylindrical. When the sleeve 20 is placed on the outside of the connecting end 103 of the needle tube 10, the central hole of the sleeve 20 is connected to the central hole of the needle tube 10, allowing the core 30 to pass through.
[0056] In this way, during the puncture, the doctor can pinch or hold the cannula 20 with his hand, so that he can operate the puncture needle without touching the needle tube 10.
[0057] like Figure 1 and Figure 5 As shown, in some embodiments, the outer wall of the connecting end 103 is provided with threads 12, and the sleeve 20 is screwed to the needle tube 10 through the threads 12.
[0058] By providing threads 12 on the outer wall of the connecting end 103 of the needle tube 10, the sleeve 20 is screwed onto the needle tube 10. This not only ensures a firm connection between the sleeve 20 and the needle tube 10, but also facilitates the assembly and disassembly of the sleeve 20. Thus, the needle tube 10 and the sleeve 20 achieve a firm connection and convenient assembly.
[0059] like Figure 5 As shown, in some embodiments, the cannula 20 includes a first tube segment 21 and a second tube segment 22. The first tube segment 21 is connected to the needle tube 10. Specifically, the first tube segment 21 of the cannula 20 is screwed to the connecting end 103 of the needle tube 10. The inner diameter of the second tube segment 22 is larger than the inner diameter of the first tube segment 21, and the length of the first tube segment 21 is... Figure 5 The length of L-L2-L3 in the middle is less than the length of the second pipe segment 22. Figure 5 L3 in the middle.
[0060] As the core 30 extends into the needle tube 10, it enters the central hole of the needle tube 10 from the port of the end of the needle tube 10 away from the needle tip 11, for example, from the opening of the sleeve 20, and then extends out of the needle tube 10 through the port of the needle tip 11.
[0061] By designing the inner diameter of the second tube segment 22 to be larger than the inner diameter of the first tube segment 21, it is convenient for the core 30 to enter the central hole of the needle tube 10 from the opening of the sleeve 20.
[0062] In the design of the aforementioned cannula 20, the outer diameter of the second segment 22 is larger than that of the first segment 21. This not only ensures the thickness of the cannula 20 but also makes it easier for the doctor to hold. Specifically, the outer diameters of the first segment 21 and the second segment 22 are determined according to actual needs and are not specifically limited here.
[0063] In order to further extend the die 30 into the center hole of the needle tube 10, the inner wall of the first tube segment 21 and the inner wall of the second tube segment 22 are typically rounded to improve the smooth transition of the die 30.
[0064] Meanwhile, by designing the length of the first tube segment 21 to be less than the length of the second tube segment 22, the contact area between the doctor and the cannula 20 is increased, making it easier for the doctor to pinch or grip the puncture needle.
[0065] In a puncture needle including needle 10 and cannula 20, when the length of the puncture needle is 175 mm, the total length of the puncture needle ( Figure 5 The length of L in the sleeve 20 is 198mm, and the length of the second pipe section 22 of the sleeve 20 is ( Figure 5 L3 in the figure is 20mm, and the length of the needle tube 10 protruding outside the cannula 20 is ( Figure 5 Since L2) is 168mm, the length of the second pipe segment 22 is 198-168-20=10mm. That is, as shown... Figure 5 As shown, the length of the first pipe section 21 is 10mm, and the length of the second pipe section 22 is 20mm.
[0066] Of course, the length of the first pipe section 21 can be 7mm, 7.5mm, 8mm, 8.2mm, 8.4mm, 8.5mm, 8.7mm, 9.9mm, 10.1mm, 10.2mm, 11mm, 12mm or 13mm in addition to 10mm, and no specific limitation is made here.
[0067] Of course, the length of the second pipe section 22 can be 20mm, or it can be 15mm, 15.1mm, 15.5mm, 15.7mm, 16mm, 17mm, 17.1mm, 18mm, 19mm, 19.5mm, 20.6mm, 21mm, 22mm, 23mm, 28mm, 30mm or 40mm, and no specific limitation is made here.
[0068] To prevent slipping, such as Figure 5 As shown, in some embodiments, the cannula 20 is provided with an anti-slip structure 40. This increases the friction between the surface of the cannula 20 and the doctor's hand during the procedure, reducing the risk of the puncture needle slipping.
[0069] The aforementioned anti-slip structure 40 can be provided with grooves and protrusions on the outside of the sleeve 20, making the outside of the sleeve 20 uneven, thereby increasing friction.
[0070] Typically, the sleeve 20 is made of plastic or silicone, so the sleeve 20 and the anti-slip structure 40 are integrally molded.
[0071] In addition, the first tube segment 21 and the second tube segment 22 are integral structures, which not only improves the strength of the sleeve 20, but also simplifies the assembly process with the needle tube 10.
[0072] It should be noted that, in the design process of the above-mentioned sleeve 20, in addition to designing the inner diameter of the second pipe section 22 to be greater than the inner diameter of the first pipe section 21 and the length of the first pipe section 21 to be less than the length of the second pipe section 22, both of which are satisfied simultaneously, the inner diameter of the second pipe section 22 can also be designed to be equal to the inner diameter of the first pipe section 21 and the length of the first pipe section 21 can be designed to be less than the length of the second pipe section 22; or, the inner diameter of the second pipe section 22 can be designed to be greater than the inner diameter of the first pipe section 21 and the length of the first pipe section 21 can be designed to be equal to the length of the second pipe section 22. No specific limitation is made here.
[0073] Normally, the needle 10 and cannula 20 are assembled and sold as a single unit. However, the puncture needle consisting only of the needle 10 can also be sold as a standalone product, or used or sold in combination with other medical devices; no specific restrictions are placed here.
[0074] In some embodiments, the puncture needle further includes a mandrel 30, which extends from the second end into the central hole of the needle tube 10 and extends from the port of the needle tip 11.
[0075] It should be noted that the syringe 10 can be sold together with the core 30, or the assembled syringe 10 and sheath 20 can be sold together with the core 30; no specific limitation is made here.
[0076] The above are merely specific embodiments of this application, but the scope of protection of this application is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the scope of the technology disclosed in this application should be included within the scope of protection of this application. Therefore, the scope of protection of this application should be determined by the scope of the claims.
Claims
1. A puncture needle for embryo transfer, characterized by comprising: The puncture needle comprises a needle tube (10), which is a rigid tube; A first end surface (101) at one end of the needle tube (10) in the length direction is arranged obliquely relative to the axis of the needle tube (10) to form a needle tip (11) for entering a living body; A first included angle (1) between the first end surface (101) and the axis of the needle tube (10) is 15°-20°.
2. The puncture needle according to claim 1, wherein The first included angle (1) is 17°.
3. The puncture needle according to claim 1, wherein Two inclined surfaces (102) are arranged at the needle tip (11) and intersect with the first end surface (101); and the two inclined surfaces (102) intersect to form an included angle (2) at the tip end close to the needle tip (11).
4. The puncture needle according to claim 3, wherein The included angle (2) is 40°-70°.
5. The puncture needle according to claim 1, wherein The length of the needle tube (10) is 165 mm-195 mm, and the outer diameter of the needle tube (10) is 2 mm.
6. The puncture needle according to any one of claims 1-5, wherein The end of the needle tube (10) away from the needle tip (11) is a connecting end (103), and a sleeve (20) is arranged at the connecting end (103) and connected to the outside of the needle tube (10).
7. The puncture needle according to claim 6, wherein The sleeve (20) comprises a first tube segment (21) and a second tube segment (22), and the first tube segment (21) is connected to the needle tube (10); The inner diameter of the second tube segment (22) is greater than or equal to the inner diameter of the first tube segment (21); And / or, the length of the first tube segment (21) is less than or equal to the length of the second tube segment (22).
8. The puncture needle according to claim 6, wherein The sleeve (20) is provided with an anti-slip structure (40).
9. The puncture needle according to claim 6, wherein The outer wall of the connecting end (103) is provided with a thread (12), and the sleeve (20) is screwed with the needle tube (10) through the thread (12).
10. The puncture needle according to any one of claims 1-5, further comprising a tube core (30), which extends into the needle tube (10) from the port at the end away from the needle tip (11) and extends out of the port of the needle tip (11).