Efficient microsphere screening device

Abstract

The utility model discloses an efficient microsphere screening device which is characterized in that the efficient microsphere screening device comprises a circulation tank, a first stirrer is arranged on one side of the bottom of the circulation tank, the bottom end of the circulation tank is connected with a microsphere screening assembly through a discharging pipe, and a rotor pump and a mass flow meter are arranged on the discharging pipe between the microsphere screening assembly and the circulation tank; and the top end of the microsphere screening assembly is connected with the feed port of the circulating tank through a return pipe. The stirring device is arranged in the screening cavity, so that uniform distribution of the microspheres is ensured, and local accumulation is avoided. And the automation degree of the equipment is further improved through the side wall automatic discharging design, the screened microspheres can be automatically discharged through a side wall outlet, manual intervention is reduced, and the production efficiency is improved.

Description

A high-efficiency microsphere sieving device Technical Field

[0001] This utility model relates to a high-efficiency microsphere sieving device. Background Technology

[0002] Microsphere sieving technology has important applications in the preparation of drug-loaded microspheres, vaccines, biological agents, and complex injectable formulations. It is mainly used to separate, purify, and classify microspheres of different particle sizes to meet specific process or product requirements. However, current microsphere sieving devices often suffer from screen clogging issues in practical applications due to factors such as material characteristics, screen design, and operating conditions. This results in low throughput and unstable operation. Summary of the Invention

[0003] To address the aforementioned problems, the purpose of this invention is to provide a high-efficiency microsphere screening device that is stable in operation and less prone to screen clogging.

[0004] The technical solution for realizing this utility model is as follows:

[0005] A high-efficiency microsphere screening device includes a circulation tank, a first agitator is provided on one side of the bottom of the circulation tank, the bottom of the circulation tank is connected to a microsphere screening component through a discharge pipe, a rotor pump and a mass flow meter are provided on the discharge pipe between the microsphere screening component and the circulation tank; the top of the microsphere screening component is connected to the feed port of the circulation tank through a return pipe.

[0006] The microsphere sieving assembly includes a box body, in which a screen is vertically arranged in a sieving chamber. A second stirrer is installed on the outer side of the box body on one side of the screen. The stirring blades of the stirrer extend into the sieving chamber and are placed between the screen and the box body.

[0007] A flow meter and a diaphragm valve are sequentially installed on the upper external pipe on the other side of the microsphere screening component, while a T-type filter, a pressure reducing valve, and a ball valve are sequentially installed on the lower external pipe.

[0008] The bottom surface of the circulation tank is also evenly distributed with three support feet, which are composed of legs and supports.

[0009] A sterile tank bottom valve is provided between the circulation tank and the discharge pipe.

[0010] Employing the above technical solution, the microsphere circulating screening device is a more efficient equipment for separating microspheres, its core principle being based on tangential flow filtration technology. During operation, the microsphere suspension enters the screening chamber via tangential flow; the liquid and fine particles flow out through the screen, while larger particles are retained and recycled back into the system. The feed and discharge flow rates are regulated by a precision control system to ensure the stability and efficiency of the screening process. Gas backflushing technology is used to periodically clean the screen, preventing clogging and extending its lifespan.

[0011] The screening chamber is equipped with a stirring device to ensure uniform distribution of microspheres and avoid localized accumulation. The automatic side-wall discharge design further enhances the automation level of the equipment; the screened microspheres can be automatically discharged through the side-wall outlet, reducing manual intervention and improving production efficiency. Attached Figure Description

[0012] Figure 1 is a schematic diagram of the structure of this utility model;

[0013] In the attached diagram, 1 is the circulating tank, 2 is the first agitator, 3 is the microsphere screening assembly, 4 is the discharge pipe, 5 is the rotor pump, 6 is the mass flow meter, 7 is the reflux pipe, 8 is the diaphragm valve, 9 is the T-type filter, 10 is the pressure reducing valve, 11 is the ball valve, and 12 is the support foot.

[0014] 3.1 is the box body, 3.2 is the screening chamber, 3.3 is the screen, 3.4 is the second agitator, and 3.5 is the agitator blade. Detailed Implementation

[0015] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this utility model. All other embodiments obtained by those skilled in the art based on the described embodiments of this utility model without creative effort are within the scope of protection of this utility model.

[0016] A high-efficiency microsphere screening device includes a circulation tank 1, with a first agitator 2 located on one side of the bottom of the circulation tank. The tank contains a microsphere liquid suspension, which is mixed by the first agitator to prevent sedimentation. The bottom of the circulation tank is connected to a microsphere screening assembly 3 via a discharge pipe. A rotor pump 5 and a mass flow meter 6 are installed on the discharge pipe 4 between the microsphere screening assembly and the circulation tank. The top of the microsphere screening assembly is connected to the inlet of the circulation tank via a return pipe 7 to send larger particles that are trapped back into the circulation tank to be dispersed by the first agitator and participate in the circulation. During operation, the microsphere suspension enters the screening chamber tangentially. The liquid and fine particles flow out through the screen, while larger particles are trapped and recycled back to the system. Since the filtration direction is perpendicular to the liquid flow direction, the flow rate is controlled by flow meters and regulating valves at the inlet and outlet. The feed and discharge flow rates are regulated by a precision control system to ensure the stability and efficiency of the screening process.

[0017] The microsphere sieving assembly includes a housing 3.1, a sieve 3.3 vertically arranged in a sieving chamber 3.2 within the housing, and a second stirrer 3.4 installed on the outer side of the housing on one side of the sieve to accelerate material separation; the stirring blades 3.5 of the stirrer extend into the sieving chamber and are positioned between the sieve and the housing. A stirring device is provided inside the sieving chamber to ensure uniform distribution of microspheres and avoid localized accumulation.

[0018] On the other side of the microsphere screening assembly, a flow meter and a diaphragm valve 8 are sequentially installed on the upper external pipe, while a T-type filter 9, a pressure reducing valve 10, and a ball valve 11 are sequentially installed on the lower external pipe. The side wall serves as the automatic discharge side, further enhancing the automation level of the equipment. Screened microspheres can be automatically discharged through the side wall outlet, reducing manual intervention and improving production efficiency. The ball valve, pressure reducing valve, and T-type filter are air inlets used for purging the screen, while the flow meter and regulating valve are used for flow rate control.

[0019] The bottom surface of the circulation tank is also evenly distributed with three support feet 12, each support foot consisting of a leg and a support base. The support feet are used to support the circulation tank.

[0020] A sterile tank bottom valve is provided between the circulation tank and the discharge pipe.

Claims

1. A high-efficiency microsphere sieving device, characterized in that, The device includes a circulation tank, a first agitator on one side of the bottom of the circulation tank, and the bottom of the circulation tank is connected to the microsphere screening assembly via a discharge pipe. A rotor pump and a mass flow meter are installed on the discharge pipe between the microsphere screening assembly and the circulation tank. The top of the microsphere screening assembly is connected to the inlet of the circulation tank via a return pipe.

2. The high efficiency microsphere sizing device of claim 1, wherein, The microsphere sieving assembly includes a box body, in which a screen is vertically arranged in a sieving chamber. A second stirrer is installed on the outer side of the box body on one side of the screen. The stirring blades of the stirrer extend into the sieving chamber and are placed between the screen and the box body.

3. The high efficiency microsphere sizing device of claim 1, wherein, A flow meter and a diaphragm valve are sequentially installed on the upper external pipe on the other side of the microsphere screening component, while a T-type filter, a pressure reducing valve, and a ball valve are sequentially installed on the lower external pipe.

4. The high-efficiency microsphere sieving device according to claim 1, characterized in that, The bottom surface of the circulation tank is also evenly distributed with three support feet, which are composed of legs and supports.

5. The high-efficiency microsphere sieving device according to claim 1, characterized in that, A sterile tank bottom valve is provided between the circulation tank and the discharge pipe.

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