High-sensitivity LncCRHR1 detection test strip

Abstract

The utility model relates to the technical field of detection test strips, and discloses a high-sensitivity LncCRHR1 detection test strip, which solves the problem of poor detection effect of the existing detection test strip, and comprises an elisa plate, a pipettor positioning plate and a laminating positioning frame, the elisa plate consists of a support frame body and a plurality of detachable elisa units, the detachable elisa unit is clamped to the top end of the supporting frame body, the pipettor positioning plate is composed of a plate body and four L-shaped positioning clamping plates, the four L-shaped positioning clamping plates are fixedly connected to the four corners of the bottom end of the plate body respectively, and a plurality of positioning through holes are formed in the plate body; through the detection test strip, a pipettor can be positioned during pipetting, a reagent is prevented from being adhered to a tube wall, meanwhile, after film covering, a sealing film can be positioned and pressed, the sealing performance is improved, the sensitivity and accuracy of detection are further improved, and errors are reduced.

Description

A high-sensitivity LncCRHR1 test strip Technical Field

[0001] This utility model belongs to the field of test strip technology, specifically a high-sensitivity LncCRHR1 test strip. Background Technology

[0002] LncCRHR1, or human corticotropin-releasing hormone receptor 1, requires sample loading onto an ELISA plate. The process involves incubation, reagent preparation, liquid addition, and membrane covering before detection using an ELISA reader. During liquid addition, a pipette is used to drop the reagent into the groove of the ELISA plate, avoiding contact with the tube wall to prevent affecting detection accuracy. However, existing test strips lack precise pipetting positioning, relying solely on manual feel, which makes it difficult to prevent reagent from adhering to the tube wall. Furthermore, the lack of a sealing structure during membrane covering after pipetting affects the sealing effect. Therefore, this application proposes a high-sensitivity LncCRHR1 test strip. Summary of the Invention

[0003] In order to overcome the shortcomings of the prior art, this utility model provides a high-sensitivity LncCRHR1 test strip, which effectively solves the problem of poor detection effect of existing test strips.

[0004] To achieve the above objectives, this utility model provides the following technical solution: a high-sensitivity LncCRHR1 test strip, comprising an enzyme-labeled plate, a pipette positioning plate, and a film-coated positioning frame. The enzyme-labeled plate consists of a support frame and several detachable enzyme-labeled units, which are snapped onto the top of the support frame. The pipette positioning plate consists of a plate body and four L-shaped positioning plates, which are respectively fixedly connected to the four corners of the bottom of the plate body. Several positioning through holes are provided on the plate body.

[0005] Preferably, the detachable enzyme labeling unit consists of a strip plate and several reagent tube slots, with the reagent tube slots located at the bottom of the strip plate. The strip plate and the reagent tube slots are an integral structure, and several pipetting holes communicating with the reagent tube slots are provided on the strip plate.

[0006] Preferably, both ends of the bottom of the strip plate are fixedly provided with a clamping plate, and a limit clamping head is fixedly provided at the bottom end of the clamping plate on the side away from the strip plate. The clamping plate is a deformable structure.

[0007] Preferably, the support frame is provided with a plurality of strip-shaped mounting grooves that match the detachable enzyme labeling unit, and both ends of the strip-shaped mounting grooves are provided with limiting slots that match the limiting card heads.

[0008] Preferably, a pry groove is provided at the middle position of both ends of the strip plate.

[0009] Preferably, the inner sidewall of the film-coated positioning frame is provided with a rectangular rubber ring.

[0010] Preferably, the center point of the positioning through hole coincides with the center point of the reagent tube groove and the pipetting hole.

[0011] Compared with the prior art, the beneficial effects of this utility model are:

[0012] (1) In the work, by setting up an enzyme label plate consisting of a support frame and several detachable enzyme label units, the detachable enzyme label units can be flexibly disassembled and assembled. Thus, if a pipetting deviation occurs during pipetting, the detachable enzyme label unit can be disassembled and replaced individually, avoiding the scrapping of the entire enzyme label plate.

[0013] (2) By setting a pipette positioning plate consisting of a plate body and four L-shaped positioning plates, and setting positioning through holes, the pipette can be accurately positioned, avoiding the pipette outlet from shifting and causing the reagent to stick to the tube wall, thereby improving the sensitivity and accuracy of the detection and reducing the error.

[0014] (3) By setting up a film-coating positioning frame and a rectangular rubber ring, the sealing film can be pressed and limited after film coating, improving the sealing performance, avoiding reagent exposure, and further improving the sensitivity and accuracy of detection. Attached Figure Description

[0015] The accompanying drawings are provided to further understand the present invention and form part of the specification. They are used together with the embodiments of the present invention to explain the present invention and do not constitute a limitation thereof.

[0016] In the attached diagram:

[0017] Figure 1 is a schematic diagram of the structure of the high-sensitivity LncCRHR1 test strip of this utility model;

[0018] Figure 2 is a schematic diagram of the structure of the enzyme-labeled plate of this utility model;

[0019] Figure 3 is a partial enlarged view of point A in Figure 2 of this utility model;

[0020] Figure 4 is a schematic diagram of the detachable enzyme labeling unit structure of this utility model;

[0021] Figure 5 is a schematic diagram of the connection structure between the enzyme-labeled plate and the pipette positioning plate of this utility model.

[0022] Figure 6 is a schematic diagram of the structure of the enzyme-labeled plate and the film-coated positioning frame of this utility model;

[0023] In the diagram: 1. ELISA plate; 2. Pipette positioning plate; 3. Covered positioning frame; 4. Support frame; 5. Detachable ELISA unit; 6. Plate body; 7. L-shaped positioning card plate; 8. Positioning through hole; 9. Strip plate; 10. Reagent tube slot; 11. Pipette hole; 12. Card plate; 13. Limiting card head; 14. Strip mounting groove; 15. Limiting card groove; 16. Pry groove; 17. Rectangular rubber ring. Detailed Implementation

[0024] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. All other embodiments obtained by those skilled in the art based on the embodiments of the present utility model without creative effort are within the protection scope of the present utility model.

[0025] As shown in Figures 1 to 6, this utility model provides a high-sensitivity LncCRHR1 test strip, which includes an enzyme-labeled plate 1, a pipette positioning plate 2, and a film-coated positioning frame 3. The enzyme-labeled plate 1 is composed of a support frame 4 and several detachable enzyme label units 5. The detachable enzyme label units 5 are snapped onto the top of the support frame 4. The pipette positioning plate 2 is composed of a plate body 6 and four L-shaped positioning plates 7. The four L-shaped positioning plates 7 are respectively fixedly connected to the four corners of the bottom end of the plate body 6. Several positioning through holes 8 are provided on the plate body 6.

[0026] The detachable enzyme labeling unit 5 can be disassembled and assembled, so that if the reagent deviates during the pipetting process, the detachable enzyme labeling unit 5 at that position can be replaced individually without replacing the entire enzyme labeling plate 1. During the pipetting process, the pipette positioning plate 2 is installed on the top of the enzyme labeling plate 1, the plate body 6 is attached to the top surface of the enzyme labeling plate 1, and the four L-shaped positioning plates 7 achieve positioning. The pipette is inserted into the positioning through hole 8, which can improve the accuracy of the pipetting process. During the coating process, the sealing film is covered on the top surface of the enzyme labeling plate 1, and then the coating positioning frame 3 is clipped onto the enzyme labeling plate 1, which can compress and limit the sealing film, improve the sealing performance, and thus improve the sensitivity and accuracy of the detection and reduce the error.

[0027] The detachable enzyme labeling unit 5 consists of a strip plate 9 and several reagent tube slots 10. The reagent tube slots 10 are located at the bottom of the strip plate 9. The strip plate 9 and the reagent tube slots 10 are an integral structure. Several pipetting holes 11 communicating with the reagent tube slots 10 are provided on the strip plate 9.

[0028] The strip plate 9 supports the reagent tube trough 10, which can store reagents, and the pipetting hole 11 can position the pipette.

[0029] Both ends of the bottom of the strip plate 9 are fixedly provided with a clamping plate 12. The bottom end of the clamping plate 12 away from the strip plate 9 is fixedly provided with a limiting clamping head 13. The clamping plate 12 is a deformable structure that can be clamped with the support frame 4.

[0030] The support frame 4 has several strip-shaped mounting grooves 14 that match the detachable enzyme label unit 5. Both ends of the strip-shaped mounting groove 14 have limiting slots 15 that match the limiting head 13, which can be engaged with the limiting head 13 to form a limiting position.

[0031] The strip plate 9 has a pry groove 16 at the middle position of both ends, which makes it easy to disassemble the detachable enzyme label unit 5.

[0032] The inner wall of the film-coated positioning frame 3 is provided with a rectangular rubber ring 17, which can further improve the sealing performance;

[0033] The center point of the positioning through hole 8 coincides with the center point of the reagent tube groove 10 and the pipetting hole 11, which enables the accuracy of the pipetting process.

[0034] In operation, the ELISA plate, consisting of a support frame and several detachable ELISA units, allows for flexible assembly and disassembly of these units. This means that if pipetting deviation occurs, the individual detachable ELISA unit can be removed and replaced, preventing the entire plate from being rendered unusable. The pipette positioning plate, consisting of the plate body and four L-shaped positioning clips, along with positioning through-holes, enables precise pipette positioning, preventing pipette outlet deviation and reagent adhesion to the tube wall, thus improving detection sensitivity and accuracy while reducing errors. Finally, the film-coated positioning frame and rectangular rubber ring ensure tight sealing after film coating, improving airtightness and preventing reagent exposure, further enhancing detection sensitivity and accuracy.

Claims

1. A high-sensitivity LncCRHR1 detection test strip, comprising an enzyme-labeled plate (1), a pipette positioning plate (2), and a film-coated positioning frame (3), characterized in that: The enzyme label plate (1) consists of a support frame (4) and several detachable enzyme label units (5). The detachable enzyme label units (5) are snapped onto the top of the support frame (4). The pipette positioning plate (2) consists of a plate body (6) and four L-shaped positioning plates (7). The four L-shaped positioning plates (7) are fixedly connected to the four corners of the bottom of the plate body (6). Several positioning through holes (8) are opened on the plate body (6).

2. The high-sensitivity LncCRHR1 test strip according to claim 1, characterized in that: The detachable enzyme labeling unit (5) consists of a strip plate (9) and several reagent tube slots (10). The reagent tube slots (10) are located at the bottom of the strip plate (9). The strip plate (9) and the reagent tube slots (10) are an integral structure. Several pipetting holes (11) communicating with the reagent tube slots (10) are opened on the strip plate (9).

3. The high-sensitivity LncCRHR1 test strip according to claim 2, characterized in that: Both ends of the bottom of the strip plate (9) are fixedly provided with a clamping plate (12). The bottom end of the clamping plate (12) away from the strip plate (9) is fixedly provided with a limit clamping head (13). The clamping plate (12) is a deformable structure.

4. The high-sensitivity LncCRHR1 test strip according to claim 3, characterized in that: The support frame (4) has several strip-shaped mounting grooves (14) that match the detachable enzyme label unit (5). Both ends of the strip-shaped mounting groove (14) have limiting slots (15) that match the limiting card head (13).

5. The high-sensitivity LncCRHR1 test strip according to claim 2, characterized in that: The strip plate (9) has pry grooves (16) at the middle positions of both ends.

6. The high-sensitivity LncCRHR1 test strip according to claim 1, characterized in that: The inner wall of the film-coated positioning frame (3) is provided with a rectangular rubber ring (17).

7. The high-sensitivity LncCRHR1 test strip according to claim 2, characterized in that: The center point of the positioning through hole (8) coincides with the center point of the reagent tube groove (10) and the pipetting hole (11).

Images