One-time centrifugal blood platelet-rich plasma preparation device

Abstract

The utility model discloses a one-time centrifugation blood platelet-rich plasma preparation device, which comprises a device main body, an upper cover and a red blood cell storage cover, the device main body is in a shape of tightening towards the center, the tightening part forms a blood channel and is provided with a rotary switch, and a platelet plasma storage chamber is arranged above the rotary switch; a suction hole is formed in the platelet plasma storage chamber, an erythrocyte storage chamber is arranged below the rotary switch, and the connecting depth of the erythrocyte storage cover and the device body can be adjusted to change the capacity of the erythrocyte storage chamber. The operation process can be remarkably simplified through the single-time centrifugal technology, the personal error risk caused by multiple times of operation is reduced, and the method is particularly suitable for clinical rapid processing or medical scenes with limited resources. In addition, mechanical damage to platelets and growth factors can be effectively reduced by reducing the number of times of centrifugation, higher cell activity and functions can be reserved, and therefore the treatment effect of the PRP is further improved.

Description

Technical Field

[0001] This utility model relates to the field of blood separation device technology, and in particular to a device for preparing platelet-rich plasma from blood after single centrifugation. Background Technology

[0002] Blood is mainly composed of plasma, platelets, and blood cells, with platelets rich in components essential for tissue regeneration and repair. During blood centrifugation, plasma, platelets, and blood cells are separated based on their weight differences, forming platelet-rich plasma (PRP) and platelet-poor plasma (PPP). Because platelets contain various growth factors, they play a crucial role in wound healing and skin regeneration. Research reports indicate that high-concentration PRP, rich in platelets, contains various growth factors that promote peripheral cell proliferation and significantly enhance the synthesis of components such as collagen. Therefore, PRP has been widely used in various medical fields, including the treatment of back pain, hair loss, skin regeneration, and burn treatment.

[0003] Currently, most existing blood separation devices use a two-stage centrifugation method to obtain platelet-rich plasma (PRP). This method requires a first centrifugation to separate the red blood cell layer, followed by a second centrifugation to separate the PRP. The overall operation is cumbersome and time-consuming, causing patients to wait for extended periods and significantly impacting clinical treatment efficiency. Therefore, developing an efficient and convenient single-stage centrifugation device for preparing platelet-rich plasma has significant clinical application value and practical significance. Utility Model Content

[0004] The technical problem to be solved by this utility model is to overcome the defects of the existing technology and provide a preparation device that can obtain high-concentration platelet-rich plasma in a single centrifugation.

[0005] The technical solution adopted by this utility model to solve its technical problem is: a device for preparing platelet-rich plasma by single centrifugation, comprising a device body, a top cover, and a red blood cell storage cover. The top cover covers the top of the device body, and the red blood cell storage cover is connected to the bottom of the device body. The device body is shaped to tighten towards the center, and the tightened part forms a blood channel and is equipped with a rotary switch. The area above the rotary switch is the platelet-rich plasma storage chamber, and the area below the rotary switch is the red blood cell storage chamber. The connection depth between the red blood cell storage cover and the device body is adjustable to adjust the height of the layered cross section. The platelet-rich plasma storage chamber is provided with a suction hole.

[0006] Furthermore, the top cover is connected to the main body of the device by threads.

[0007] Furthermore, the red blood cell storage cap is connected to the main body of the device by a thread, and the capacity of the red blood cell storage chamber can be changed by rotating the thread, thereby achieving the purpose of fine-tuning the height of the layered cross section.

[0008] Furthermore, a silicone cap is installed on the suction hole.

[0009] Furthermore, the main body of the device is provided with a scale.

[0010] Furthermore, the main body of the device is equipped with sealing rings at the connection points with the top cover and the red blood cell storage cover.

[0011] Furthermore, the rotary switch is provided with a radially penetrating through hole, and by changing the relative position of the through hole and the blood channel, the platelet plasma storage chamber and the red blood cell storage chamber can be connected or blocked.

[0012] The beneficial effects of this novel device for preparing platelet-rich plasma by single-pass centrifugation are:

[0013] 1. High efficiency and time saving: Overcoming the technical limitations of traditional two-stage centrifugation for obtaining platelet-rich plasma (PRP), this method employs a single centrifugation process, significantly reducing the overall operation. It avoids the repetitive operations and waiting time required for secondary centrifugation, effectively improving blood processing efficiency and significantly shortening patient waiting periods. It is particularly suitable for emergency clinical treatment scenarios, saving patients valuable treatment time.

[0014] 2. Simple operation and high precision: The uniquely designed combination of the red blood cell storage cap and rotary switch allows for flexible adjustment of the connection depth based on the red blood cell stratification state, precisely controlling and locking the stratification interface at the upper edge of the rotary switch. This design significantly reduces the difficulty of operation, simplifies the operation steps, reduces human error, ensures the accuracy and consistency of PRP separation results, and makes the operation process easier to standardize and regulate.

[0015] 3. Protecting cell activity: By reducing the number of centrifugation cycles, mechanical damage to platelets and growth factors during centrifugation is reduced, preserving the biological activity of platelets and the function of growth factors to the greatest extent, which helps to improve the therapeutic effect of PRP in clinical applications such as wound repair and skin regeneration. Attached Figure Description

[0016] The present invention will be further described below with reference to the accompanying drawings and embodiments.

[0017] Figure 1 This is a schematic diagram of the structure of this utility model;

[0018] Figure 2 This is a cross-sectional structural diagram of the present invention;

[0019] Figure 3This is a schematic diagram of the main body of the device of this utility model;

[0020] Figure 4 This is a schematic diagram of the structure of the rotary switch of this utility model;

[0021] In the diagram: 1. Red blood cell storage cap, 2. Sealing ring, 3. Rotary switch, 4. Main body of the device, 5. Top cover, 6. Through hole, 7. Suction hole. Detailed Implementation

[0022] The present invention will now be described in further detail with reference to the accompanying drawings. These drawings are simplified schematic diagrams, illustrating only the basic structure of the present invention, and therefore only show the components relevant to the present invention.

[0023] As shown in the figure, a single-cycle centrifugation blood platelet-rich plasma preparation device includes a device body 4, an upper cover 5, and a red blood cell storage cover 1. The upper cover 5 is connected to the device body 4 by a thread and covers the top of the device body 4, while the red blood cell storage cover 1 is connected to the bottom of the device body 4.

[0024] The main body 4 of the device is shaped to taper towards the center. The tapered part forms a blood channel and is equipped with a rotary switch 3. The area above the rotary switch 3 is the platelet plasma storage chamber, and the area below the rotary switch 3 is the red blood cell storage chamber. A radially penetrating through hole 6 is provided on the rotary switch 3. By changing the relative position of the through hole 6 and the blood channel, the platelet plasma storage chamber and the red blood cell storage chamber can be connected or blocked.

[0025] The red blood cell storage cap 1 is threadedly connected to the main body 4 of the device. The connection depth between the two can be changed by rotating the thread, so as to achieve the purpose of fine-tuning the height of the layered cross section.

[0026] The platelet plasma storage chamber is equipped with a suction port 7, which is fitted with a silicone cap. The main body 4 of the device is fitted with sealing rings 2 at the connection points with the top cover 5 and the red blood cell storage cover 1, thereby improving the overall sealing and reliability of the device.

[0027] The main body 4 of the device is equipped with a scale, which makes it easy for operators to accurately control the amount of plasma extracted and ensure that the target volume of PRP is obtained in the end.

[0028] The operation and usage steps of this utility model are as follows:

[0029] 1. Blood injection:

[0030] Before operation, ensure the device is clean and sterile, and check that the rotary switch 3 is in the open position. Slowly inject the blood to be processed into the main body 4 of the device through the suction port 7, filling it to the designated mark (leaving space for stratification after centrifugation). Avoid generating air bubbles during the injection process.

[0031] 2. Centrifugation procedure:

[0032] Place the blood-containing device smoothly into the corresponding slot of the centrifuge. Set the centrifuge speed and centrifugation time according to the characteristics of the blood sample and experimental requirements, and start the centrifuge.

[0033] 3. Red blood cell storage cap adjustment and locking:

[0034] After centrifugation, carefully remove the device and observe the stratification of red blood cells through the transparent material of the device.

[0035] When the layered position is above the rotary switch 3, slowly rotate the red blood cell storage cover 1 in the left-hand direction to gradually reduce the connection depth between the red blood cell storage cover 1 and the main body 4 of the device, so that the layered interface gradually moves down.

[0036] When the layer position is below the rotary switch 3, rotate the red blood cell storage cover 1 in the right-hand direction to increase the connection depth and slowly move the layer interface upward;

[0037] During fine-tuning, the position of the layer interface needs to be continuously observed until it is precisely located at the upper edge of the rotary switch 3. Then, quickly rotate the rotary switch 3 to the locked position to ensure that the red blood cells are sealed in the red blood cell storage chamber and prevent interlayer mixing during subsequent operations.

[0038] 4. Plasma extraction:

[0039] Insert a sterile injection needle into the main body 4 of the device through the aspiration port 7, and slowly draw up the upper layer of anemic platelet plasma (PPP) according to the scale information marked on the outside of the main body 4 (precisely displaying the target PRP volume). Stop the operation after the predetermined amount of plasma has been drawn.

[0040] After extraction, the remaining portion inside the main body 4 of the device is platelet-rich plasma (PRP). The PRP is then completely extracted into the storage container through the aspiration port 7 using a new sterile syringe.

[0041] Based on the above-described preferred embodiments of this utility model, and through the foregoing description, those skilled in the art can make various changes and modifications without departing from the technical concept of this utility model. The technical scope of this utility model is not limited to the contents of the specification, but must be determined according to the scope of the claims.

Claims

1. A device for preparing platelet-rich plasma by single-pass centrifugation, characterized in that: The device includes a main body (4), a top cover (5), and a red blood cell storage cover (1). The top cover (5) covers the top of the main body (4), and the red blood cell storage cover (1) is connected to the bottom of the main body (4). The main body (4) is shaped to tighten towards the center. The tightened part forms a blood channel and is equipped with a rotary switch (3). The area above the rotary switch (3) is a platelet plasma storage chamber, and the area below the rotary switch (3) is a red blood cell storage chamber. The connection depth between the red blood cell storage cover (1) and the main body (4) is adjustable to adjust the height of the layered section. The platelet plasma storage chamber is provided with a suction hole (7).

2. The apparatus for preparing platelet-rich plasma by single-pass centrifugation of blood according to claim 1, characterized in that: The top cover (5) is connected to the main body (4) of the device by threads.

3. The apparatus for preparing platelet-rich plasma by single-pass centrifugation of blood according to claim 1, characterized in that: The red blood cell storage cover (1) and the main body of the device (4) are connected by threads. The capacity of the red blood cell storage chamber is changed by rotating the threads, so as to achieve the purpose of fine-tuning the height of the layered section.

4. The apparatus for preparing platelet-rich plasma by single-pass centrifugation of blood according to claim 1, characterized in that: A silicone cap is installed on the suction hole (7).

5. The apparatus for preparing platelet-rich plasma by single-pass centrifugation of blood according to claim 1, characterized in that: The main body (4) of the device is provided with a scale.

6. The apparatus for preparing platelet-rich plasma by single-pass centrifugation of blood according to claim 1, characterized in that: The main body (4) of the device is equipped with sealing rings (2) at the connection points with the upper cover (5) and the red blood cell storage cover (1).

7. The apparatus for preparing platelet-rich plasma by single-pass centrifugation of blood according to claim 1, characterized in that: The rotary switch (3) is provided with a radially penetrating through hole (6). By changing the relative position of the through hole (6) and the blood channel, the platelet plasma storage chamber and the red blood cell storage chamber can be connected or blocked.

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