Automatic uncovering device for PCR (Polymerase Chain Reaction) tubes

Abstract

The utility model relates to the field of automatic uncovering of reaction tubes, and discloses an automatic uncovering device for PCR reaction tubes. According to the washing machine, a cover is fixedly connected to the lower portion of the pressing connecting pipe, a pressing column is installed in the cover, a strong spring is arranged on the periphery of the pressing column, a detergent storage bin is arranged below the cover, and a washing machine outflow opening is connected to the lower portion of the detergent storage bin; when the washing machine is used, the washing liquid flows into the washing liquid storage bin, after the outflow amount is appropriate, pressing is stopped, the washing liquid can stop flowing out, the outflow amount of the washing liquid can be conveniently controlled, the remaining washing liquid can be placed in the washing liquid storage bin and then flows into the transmission column through the washing machine outflow opening, the washing liquid can better flow into the sponge ball, and therefore the washing liquid can be better cleaned. The sponge ball can be more sufficiently and averagely adsorbed to the detergent, so that the interior of the reaction tube can be better and comprehensively cleaned, and the use convenience is improved.

Description

Technical Field

[0001] This application belongs to the field of automated reaction tube opening technology, specifically an automated PCR reaction tube opening device. Background Technology

[0002] Reaction tubes have a very broad application prospect in hospitals, especially in bacterial culture and identification and biomedical research. They are an indispensable experimental consumable in the process of bacterial culture and identification in the laboratory. The biochemical reaction characteristics of bacteria on the reaction tube are used to determine the bacterial genus. In hospitals, their main applications include PCR reactions and their importance to medical diagnosis. PCR (Polymerase Chain Reaction) is a classic method in molecular diagnostic testing, and the design and technical characteristics of the reaction tube, as the carrier of the PCR reaction system, have a significant impact on the efficiency and accuracy of the PCR reaction.

[0003] For example, CN211712585U discloses an automated capping device for PCR reaction tubes, belonging to the field of medical supplies technology. It includes a clamping structure, a capping structure, and a tube rack; the tube rack is equipped with a clamping structure for holding the reaction tubes, and a slidable capping structure for opening the caps of the reaction tubes. This invention, by setting the clamping structure, can clamp and fix the reaction tubes on the tube rack, preventing them from tipping over when opening; by setting the capping structure, it can open the caps of reaction tubes in the same row simultaneously, saving time. This invention, by setting anti-slip soft rubber pads inside the arc-shaped parts of the fixed clamping plate and the movable clamping plate, increases friction, better fixing the reaction tubes during capping, preventing them from tipping over, and allowing the caps of the reaction tubes to be opened smoothly.

[0004] However, in common applications, it is difficult to clean the inside of the reaction tubes after use. Manual cleaning is too time-consuming and labor-intensive, which may lead to an increase in uncleaned reaction tubes, which cannot meet the demand, greatly reducing the efficiency of use and making it difficult for later use and cleaning. Utility Model Content

[0005] The purpose of this application is to provide an automated capping device for PCR reaction tubes in order to solve the aforementioned problem of cleaning the inside of the reaction tubes.

[0006] The technical solution adopted in this application is as follows: An automated capping device for PCR reaction tubes includes a fixing frame, a button is provided on the upper surface of the fixing frame, a pressing connecting tube is connected below the button, a cap is fixedly connected below the pressing connecting tube, a pressing column is installed inside the cap, a strong spring is provided around the pressing column, a detergent storage compartment is provided below the cap, a detergent outlet is connected below the detergent storage compartment, a transmission column is connected to the lower surface of the detergent outlet, a sponge ball is connected to the outer surface of the transmission column, a brush is provided on the surface of the sponge ball, and a silicone pad is fixedly installed at the bottom of the transmission column.

[0007] By adopting the above technical solution, when cleaning the internal parts of the reaction tube, a button is installed to press the pressing column and the strong spring, allowing the detergent to flow into the detergent storage chamber. Once the flow rate is appropriate, pressing stops, and the detergent flow stops, making it easy to control the amount of detergent flowing out. Any remaining detergent is stored in the detergent storage chamber, avoiding waste caused by overuse and improving the convenience of cleaning the reaction tube. The detergent flows into the transmission column through the washing machine outlet, allowing it to better flow into the sponge balls, enabling the sponge balls to absorb the detergent more fully and evenly, facilitating a more thorough cleaning of the inside of the reaction tube and improving ease of use. The installed brush further cleans any areas missed by the sponge balls, making the inner wall of the reaction tube cleaner and more tidy, further improving the convenience and cleanliness of cleaning. The installation of a silicone pad prevents damage to the internal parts of the reaction tube during the cleaning process, better protecting the safety and integrity of the reaction tube and improving the overall safety of the device.

[0008] In a preferred embodiment, bolts are provided on both sides of the fixing frame. A telescopic frame is connected below the bolts, and push-to-shoulder telescopic sliders are provided on both sides of the telescopic frame. A vertical sliding groove is provided below the telescopic frame.

[0009] By adopting the above technical solution, the cleaning device can be made more stable by installing bolts, and the interior of the reaction tube can be cleaned more conveniently by installing the up-and-down moving device, making it more stable and convenient.

[0010] In a preferred embodiment, a movable column is mounted on the outer surface of the vertical movable slide, and transverse movable sliders are provided on both sides of the movable column.

[0011] By adopting the above technical solution, the installation of a movable column allows for more stable movement, which not only facilitates cleaning but also stabilizes the vertical movement device, making it more stable.

[0012] In a preferred embodiment, a moving groove is provided below the lateral moving slider, and a lateral moving slide groove is provided inside the moving groove.

[0013] By adopting the above technical solution, the reaction tube can be pushed back and forth by installing a lateral moving device, which can be used to clean the reaction tube more thoroughly, making the cleaning more convenient and faster.

[0014] In a preferred embodiment, a lower tube rack is installed below the moving trough, and a reaction tube placement box is fixedly installed on one side of the lower tube rack.

[0015] By adopting the above technical solution, the installation of the movable column can be more secure by installing bolts, making the device more stable and safer when moving, thus improving its stability.

[0016] In a preferred embodiment, the upper surface of the reaction tube placement box is provided with a tube-prevention hole.

[0017] By adopting the above technical solution, the reaction tube can be more securely placed in the reaction tube box by installing a hole to prevent shaking and damage to the reaction tube, thus making it safer and more reliable.

[0018] In a preferred embodiment, an end cap is provided on the upper surface of the prevention tube hole, a reaction tube is connected below the end cap, and an anti-detachment connecting strap is installed on one side of the end cap.

[0019] By adopting the above technical solution and installing the anti-detachment connecting strap, the end cap can be opened or closed more easily, and safety can be ensured during use, making it more convenient and safer for users.

[0020] In a preferred embodiment, a connecting rod is provided on the upper surface of the lower tube rack, and movable clamping plates are connected to both sides of the connecting rod. A fixed clamping plate is provided below the movable clamping plates.

[0021] By adopting the above technical solution, the reaction tubes in the upper surface of the reaction tube placement box can be clamped and fixed by setting a clamping structure, preventing the reaction tubes from being knocked over and spilled when opened, thus making them more stable.

[0022] In summary, due to the adoption of the above technical solution, the beneficial effects of this application are:

[0023] In this application, during the internal cleaning of the reaction tube, a button is installed to press the pressing column and the strong spring, allowing detergent to flow into the detergent storage chamber. Once the flow rate is appropriate, pressing is stopped, and the detergent flow stops, facilitating control of the detergent flow rate. Remaining detergent is stored in the detergent storage chamber, avoiding waste caused by overuse and improving the convenience of cleaning the reaction tube. The detergent flows into the transmission column through the washing machine outlet, allowing it to better flow into the sponge balls, enabling the sponge balls to absorb the detergent more fully and evenly, facilitating a more thorough cleaning of the inside of the reaction tube and improving ease of use. The installed brush further cleans any areas missed by the sponge balls, making the inner wall of the reaction tube cleaner and improving the convenience and cleanliness of cleaning. The installation of a silicone pad prevents damage to the inside of the reaction tube during the cleaning process, better protecting the safety and integrity of the reaction tube and improving the overall safety of the device. Attached Figure Description

[0024] Figure 1 This is a schematic diagram of the overall device structure of this application;

[0025] Figure 2 This is a schematic diagram of the reaction tube structure in this application;

[0026] Figure 3 This is a schematic diagram of the planar structure of the clamping plate in this application;

[0027] Figure 4 This is a schematic diagram of the lower tube rack structure in this application;

[0028] Figure 5 This is a schematic diagram of the mobile device structure in this application;

[0029] Figure 6 This is a schematic diagram of the overall structure of the cleaning device in this application;

[0030] Figure 7 This is a schematic diagram of the internal structure of the lid in this application;

[0031] Figure 8 This is a schematic diagram of the brush structure in this application.

[0032] The diagram shows the following markings: 1. Reaction tube placement box; 2. Placement tube hole; 3. Lower tube rack; 4. Connecting rod; 5. Fixing frame; 6. Bolt; 7. End cap; 8. Anti-detachment connecting strap; 9. Reaction tube; 10. Fixing clamping plate; 11. Moving clamping plate; 12. Lateral moving slide; 13. Moving groove; 14. Lateral moving slider; 15. Moving column; 16. Up and down moving slide; 17. Press-type telescopic slider; 18. Telescopic frame; 19. Button; 20. Press-connecting tube; 21. Cover; 22. Detergent storage compartment; 23. Detergent outlet; 24. Transmission column; 25. Sponge ball; 26. Silicone pad; 27. Pressing column; 28. Strong spring; 29. ​​Brush. Detailed Implementation

[0033] To make the objectives, technical solutions, and advantages of the embodiments of this application clearer, the technical solutions in the embodiments of this application will be clearly and completely described below in conjunction with the embodiments of this application. Obviously, the described embodiments are only some embodiments of this application, not all embodiments. Based on the embodiments in this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application. Example

[0034] Reference Figure 1-8 An automated capping device for PCR reaction tubes includes a mounting bracket 5. A button 19 is mounted on the upper surface of the mounting bracket 5. A pressing connection tube 20 is connected below the button 19, and a cap 21 is fixedly connected below the pressing connection tube 20. A pressing column 27 is installed inside the cap 21, and a strong spring 28 is arranged around the pressing column 27. A detergent storage chamber 22 is located below the cap 21, and a detergent outlet 23 is connected below the detergent storage chamber 22. When cleaning the reaction tube 9 internally, the button 19 is used to press the pressing column 27 and the strong spring 28, causing detergent to flow into the detergent storage chamber 22. Once the desired flow rate is reached, pressing is stopped, and the detergent flow stops, allowing for easy control of the detergent flow rate. Any remaining detergent is stored in the detergent storage chamber 22, avoiding waste caused by overuse and improving the convenience of cleaning the reaction tube 9.

[0035] Reference Figure 1-8A drive column 24 is connected to the lower surface of the washing machine outlet 23. A sponge ball 25 is connected to the outer surface of the drive column 24, and a brush 29 is provided on the surface of the sponge ball 25. When detergent flows into the drive column 24 through the washing machine outlet 23, it allows the detergent to flow more effectively into the sponge ball 25, enabling the sponge ball 25 to absorb the detergent more fully and evenly. This facilitates a more thorough cleaning of the inside of the reaction tube 9, improving ease of use. The brush 29 further cleans any parts of the sponge ball 25 that were not cleaned, making the inner wall of the reaction tube 9 cleaner and more convenient to clean.

[0036] Reference Figure 6 A silicone pad 26 is fixedly installed at the bottom of the transmission column 24. The installation of the silicone pad 26 can prevent damage to the inside of the reaction tube 9 during the cleaning process, better protect the safety and integrity of the reaction tube 9, and improve the overall safety of the device.

[0037] Reference Figure 1 and 5 Bolts 6 are provided on both sides of the fixed frame 5. A telescopic frame 18 is connected below the bolts 6. Press-type telescopic sliders 17 are provided on both sides of the telescopic frame 18, and a vertical sliding groove 16 is provided below the telescopic frame 18. Installing bolts 6 can make the cleaning device more stable, and installing the vertical sliding device can make it easier to clean the inside of the reaction tube 9, making it more stable and convenient.

[0038] Reference Figure 4-5 A movable column 15 is installed on the outer surface of the vertical sliding groove 16, and a horizontal sliding block 14 is provided on both sides of the movable column 15. By installing the movable column 15, the movement can be more stable, which not only facilitates cleaning, but also stabilizes the vertical moving device, making it more stable.

[0039] Reference Figure 4-5 A moving groove 13 is provided below the horizontally moving slider 14, and a horizontally moving slide groove 12 is provided inside the moving groove 13. By installing the horizontally moving device, it can be pushed back and forth to perform a more comprehensive cleaning of the reaction tube 9, making cleaning more convenient and faster, thus improving its convenience.

[0040] Reference Figure 1-5 A lower tube rack 3 is installed below the moving trough 13, and a reaction tube placement box 1 is fixedly installed on one side of the lower tube rack 3. The installation of the moving column 15 can be further secured by the mounting bolts 6, making the device more stable and safer when moving, thus improving its stability.

[0041] Reference Figure 1-2The upper surface of the reaction tube placement box 1 is provided with a tube-prevention hole 2. By installing the tube-prevention hole 2, the reaction tube 9 can be more securely placed in the reaction tube placement box 1, avoiding shaking and damage to the reaction tube 9, thus making it safer and more reliable.

[0042] Reference Figure 1-2 An end cap 7 is provided on the upper surface of the tube hole 2, and a reaction tube 9 is connected to the lower part of the end cap 7. An anti-detachment connecting strap 8 is installed on one side of the end cap 7. By installing the anti-detachment connecting strap 8, the end cap 7 can be opened or closed more easily, and safety can be ensured during use, making it more convenient and safer for users.

[0043] Reference Figure 1-3 A connecting rod 4 is provided on the upper surface of the lower tube rack 3. Movable clamping plates 11 are connected to both sides of the connecting rod 4. A fixed clamping plate 10 is provided below the movable clamping plate 11. By setting up the clamping structure, the reaction tube 9 in the upper surface of the reaction tube placement box 1 can be clamped and fixed to prevent the reaction tube 9 from being overturned and spilled when opened, making it more stable.

[0044] The implementation principle of an embodiment of an automated capping device for reaction tubes in this application is as follows:

[0045] During the internal cleaning of the reaction tube 9, the button 19 is used to press the pressing column 27 and the strong spring 28, allowing the detergent to flow into the detergent storage chamber 22. Once the flow rate is appropriate, pressing stops the flow of detergent, making it easy to control the amount of detergent flowing out. Any remaining detergent is stored in the detergent storage chamber 22, which not only avoids waste caused by overuse but also improves the convenience of cleaning the reaction tube 9. The detergent flows into the transmission column 24 through the washing machine outlet 23, allowing it to flow better into the sponge ball 25, enabling the sponge ball 25 to absorb the detergent more fully and evenly, facilitating a more thorough cleaning of the inside of the reaction tube 9 and improving ease of use. The brush 29 installed allows for further cleaning of any parts of the sponge ball 25 that were not cleaned, making the inner wall of the reaction tube 9 cleaner and improving the convenience and thoroughness of cleaning. The silicone pad 26 installed prevents damage to the inside of the reaction tube 9 during the cleaning process, better protecting the safety and integrity of the reaction tube 9 and improving the overall safety of the device.

[0046] The above embodiments are only used to illustrate the technical solutions of this application, and are not intended to limit them. Although this application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some of the technical features. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of this application.

Claims

1. An automated capping device for PCR reaction tubes, comprising a fixing frame (5), characterized in that: A button (19) is provided on the upper surface of the fixed frame (5). A pressing connecting tube (20) is connected below the button (19). A cover (21) is fixedly connected below the pressing connecting tube (20). A pressing column (27) is installed inside the cover (21). A strong spring (28) is provided around the pressing column (27). A detergent storage compartment (22) is provided below the cover (21). A washing machine outlet (23) is connected below the detergent storage compartment (22). A transmission column (24) is connected to the lower surface of the washing machine outlet (23). A sponge ball (25) is connected to the outer surface of the transmission column (24). A brush (29) is provided on the surface of the sponge ball (25). A silicone pad (26) is fixedly installed at the bottom of the transmission column (24).

2. The automated capping device for a reaction tube as described in claim 1, characterized in that: Bolts (6) are provided on both sides of the fixed frame (5), and a telescopic frame (18) is connected below the bolts (6). Press-type telescopic sliders (17) are provided on both sides of the telescopic frame (18), and an up-and-down sliding groove (16) is provided below the telescopic frame (18).

3. The automated capping device for a reaction tube as described in claim 2, characterized in that: The outer surface of the vertical sliding groove (16) is equipped with a moving column (15), and the two sides of the moving column (15) are provided with horizontal moving sliders (14).

4. The automated capping device for a reaction tube as described in claim 3, characterized in that: A moving groove (13) is provided below the horizontal moving slider (14), and a horizontal moving slide groove (12) is provided inside the moving groove (13).

5. The automated capping device for a reaction tube as described in claim 4, characterized in that: A lower tube rack (3) is installed below the moving trough (13), and a reaction tube placement box (1) is fixedly installed on one side of the lower tube rack (3).

6. The automated capping device for a reaction tube as described in claim 5, characterized in that: The upper surface of the reaction tube placement box (1) is provided with a tube hole (2).

7. An automated capping device for a reaction tube as described in claim 6, characterized in that: An end cap (7) is provided on the upper surface of the anti-detachment tube hole (2), a reaction tube (9) is connected below the end cap (7), and an anti-detachment connecting strip (8) is installed on one side of the end cap (7).

8. An automated capping device for a reaction tube as described in claim 5, characterized in that: The upper surface of the lower tube rack (3) is provided with a connecting rod (4), and movable clamping plates (11) are connected to both sides of the connecting rod (4). A fixed clamping plate (10) is provided below the movable clamping plate (11).

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