A cell culture dish shaking device

Abstract

This utility model discloses a cell culture dish shaking device, relating to the field of cell culture equipment technology. The utility model includes a housing with a tray on top. A locking mechanism is movably connected to the top of the tray, and a shaking mechanism is fixedly connected to the inner cavity of the housing. The locking mechanism of this utility model employs a design of magnetic locking blocks engaging with slots and magnetic adsorption. When replacing the expansion plate, the experimenter only needs to align the magnetic locking block of the expansion plate with the slot on the tray, and installation can be quickly completed using magnetic force, without the need for any tools. Disassembly only requires applying an external force slightly greater than the magnetic force to separate the expansion plate from the tray, significantly saving experimental preparation and cleaning time and improving experimental efficiency. Furthermore, by replacing expansion plates of different specifications and shapes, it can adapt to cell culture dishes of different sizes, as well as diverse experimental containers such as flasks and deep-well plates, greatly enhancing the adaptability of the device to different experimental needs.

Description

Technical Field

[0001] This utility model belongs to the field of cell culture equipment technology, and in particular relates to a cell culture dish shaking device. Background Technology

[0002] In the field of cell culture experiments, cell growth and metabolism depend on a stable and suitable microenvironment. The shaking device is one of the core devices to ensure the uniform distribution of cell culture medium and promote good cell growth. During cell culture, the culture medium needs to continuously supply nutrients to the cells, buffer metabolic waste, and maintain a suitable osmotic pressure and pH value. The shaking device can break the concentration gradient in the culture medium by shaking at a specific frequency and amplitude, ensuring that the cells are in uniform contact with nutrients in the culture space, and avoiding the impact on cell activity and proliferation due to local nutrient deficiency or accumulation of metabolic waste.

[0003] However, existing shaking devices on the market have many problems. In terms of compatibility, existing shaking devices are poorly compatible with cell culture dishes, and most only support specific sizes of culture dishes. When researchers need to use cell culture dishes of different sizes, or other experimental containers such as flasks and deep-well plates, they often need to configure special accessories to achieve compatibility. In terms of speed and shaking amplitude adjustment, the shaking amplitude of existing shaking devices is mostly fixed, and it is impossible to adjust the shaking amplitude according to different types of culture dishes. The speed adjustment function has a significant deficiency, with a limited speed adjustment range that cannot cover a wide range of needs from low speed to high speed, making it difficult to adapt to the culture requirements of different cell types.

[0004] To address these issues, we provide a cell culture dish shaking device. Utility Model Content

[0005] The purpose of this invention is to provide a cell culture dish shaking device. By combining the locking mechanism and the shaking mechanism, it solves the problems of poor adaptability of existing cell culture dish shaking devices to cell culture dishes and the inability to adjust the shaking amplitude.

[0006] To solve the above-mentioned technical problems, this utility model is achieved through the following technical solution.

[0007] This utility model relates to a cell culture dish shaking device, comprising a box body, a tray on the top of the box body, a locking mechanism movably connected to the top of the tray, and a shaking mechanism fixedly connected to the inner cavity of the box body. The locking mechanism includes an extension plate located on top of the tray, a storage slot on the top of the extension plate, and magnetic blocks fixedly connected to both sides of the bottom of the extension plate. A slot is provided on the top of the tray, and the bottom of the magnetic blocks is slidably connected to the slot. A magnetic block is provided in the inner cavity of the slot, the bottom of the magnetic block is fixedly connected to the tray, and the top of the magnetic block is adsorbed to the magnetic blocks. The storage slot is used to store culture dishes, and the extension plate is made of medical-grade silicone, which enhances the friction between the extension plate and the culture dishes, ensuring that the culture dishes do not shift during shaking. Multiple storage slots can be set to simultaneously increase the area of ​​the extension plate, enabling the simultaneous shaking of multiple culture dishes and greatly improving work efficiency. The multiple magnetic blocks and slots provide precise positioning and guidance for the extension plate, and the adsorption force between the magnetic blocks and the magnetic blocks further ensures the stability of the extension plate during operation.

[0008] This invention is further configured such that the shaking mechanism includes a drive motor, one side of which is fixedly connected to the housing, and a turntable is fixedly connected to the output end of the drive motor. A fixed rod is slidably connected to the surface of the turntable, and a lead screw is threaded to one end of the fixed rod. A micro motor is fixedly connected to one side of the lead screw, which passes through the inner cavity of the turntable. A connecting rod is movably connected to one side of the micro motor, and a toothed plate is movably connected to the other end of the fixed rod. The bottom of the toothed plate is slidably connected to the housing, and a gear meshes with the top of the toothed plate. A rotating rod is fixedly connected to the inner side of the gear, and the surface of the rotating rod is fixedly connected to the tray. Both sides of the rotating rod are rotatably connected to the housing, and the other side of the lead screw is rotatably connected to the turntable. This configuration improves the stability of the lead screw during operation. The micro motor allows for rapid changes in the shaking amplitude of the tray without the need for complex disassembly or additional tools. Experimenters can flexibly adjust the mechanism according to different cell culture stages and experimental requirements.

[0009] The present invention is further configured such that a control panel is provided on one side of the rotating rod, and one side of the control panel is fixedly connected to the box body. The surface of the control panel is provided with a time setting button, a speed setting button and a start button. For different types of dishes, a more precise speed can be set, so that the cells are shaken evenly while avoiding liquid splashing and contamination.

[0010] The present invention is further configured such that a slide rail is slidably connected to the bottom of the toothed plate, and the bottom of the slide rail is fixedly connected to the housing, and the slide rail provides precise guidance and limiting for the toothed plate.

[0011] The present invention is further configured such that limit rings are provided on both sides of the connecting rod, and the inner side of the limit rings is fixedly connected to the fixed rod. There are two limit rings, which can limit the range of motion of the connecting rod.

[0012] The present invention is further configured such that a shock-absorbing pad is fixedly connected to the bottom of the box, and a rubber column is fixedly connected to the bottom of the shock-absorbing pad. The shock-absorbing pad and the rubber column form a double-layer shock-absorbing structure, which can effectively absorb the vibration generated during the operation of the shaking mechanism.

[0013] The present invention is further configured such that a slider is fixedly connected to one end of the fixed rod, a groove is provided on the surface of the turntable, one side of the slider is slidably connected to the groove, and the inner side of the slider is threadedly connected to a lead screw. The cooperation between the slider and the groove provides precise guidance for the sliding of the fixed rod on the turntable.

[0014] The present invention has the following beneficial effects.

[0015] 1. The locking mechanism of this utility model adopts a design of magnetic locking blocks and slots, and magnetic adsorption blocks. When changing the expansion plate, the experimenter only needs to align the magnetic locking block of the expansion plate with the slot on the tray, and the installation can be completed quickly by using magnetic force without the use of any tools. When disassembling, only an external force slightly greater than the magnetic force is needed to easily separate the expansion plate from the tray, which greatly saves experimental preparation and cleaning time, improves experimental operation efficiency, and can be adapted to cell culture dishes of different sizes, as well as flasks, deep well plates and other diverse experimental containers by changing expansion plates of different specifications and shapes, which greatly enhances the adaptability of the device to different experimental needs and reduces experimental costs.

[0016] 2. The shaking mechanism of this utility model is connected by a screw and a fixed rod. With the screw driven by a micro motor, the sliding position of the fixed rod on the turntable can be flexibly adjusted. This innovative design breaks the limitation of the single motion path of traditional shaking devices and can achieve shaking effects of different amplitudes and frequencies. For example, for adherent cell culture, the fixed rod can be adjusted to a position close to the center of the turntable so that the tray shakes at a smaller amplitude and lower frequency to avoid cell detachment. In suspension cell culture, the fixed rod is moved outward to increase the shaking amplitude and frequency, ensuring that the cells are fully suspended and uniformly mixed with the culture medium, meeting the differentiated culture needs of different cell types. Attached Figure Description

[0017] To more clearly illustrate the technical solutions of the embodiments of this utility model, the accompanying drawings used in the description of the embodiments will be briefly introduced below.

[0018] Figure 1 This is a three-dimensional diagram of a cell culture dish shaking device.

[0019] Figure 2This is a three-dimensional diagram of the locking mechanism in a cell culture dish shaking device.

[0020] Figure 3 This is a three-dimensional diagram of the shaking mechanism in a cell culture dish shaking device.

[0021] Figure 4 A three-dimensional view of a shock-absorbing pad in a cell culture dish shaking device.

[0022] Figure 5 This is a magnified view of point A in a cell culture dish shaking device.

[0023] In the attached diagram: 1. Box body; 2. Tray; 3. Locking mechanism; 301. Extension plate; 302. Storage slot; 303. Magnetic card block; 304. Card slot; 305. Magnetic block; 4. Shaking mechanism; 401. Drive motor; 402. Turntable; 403. Fixing rod; 404. Lead screw; 405. Micro motor; 406. Connecting rod; 407. Tooth plate; 408. Gear; 409. Rotating rod; 5. Control panel; 6. Slide rail; 7. Limiting ring; 8. Shock-absorbing pad; 9. Rubber column; 10. Slider; 11. Slide groove. Detailed Implementation

[0024] The technical solutions of the present utility model will be described below with reference to the accompanying drawings. The described embodiments are only some embodiments of the present utility model, and not all embodiments. Example 1

[0025] Please see Figure 1-5 This utility model is a cell culture dish shaking device, including a box body 1, a tray 2 on the top of the box body 1, a locking mechanism 3 movably connected to the top of the tray 2, and a shaking mechanism 4 fixedly connected to the inner cavity of the box body 1. The locking mechanism 3 includes an extension plate 301, which is located on the top of the tray 2. A storage slot 302 is opened on the top of the extension plate 301. Magnetic blocks 303 are fixedly connected to both sides of the bottom of the extension plate 301. A slot 304 is opened on the top of the tray 2. The bottom of the magnetic blocks 303 is slidably connected to the slot 304. A magnetic block 305 is provided in the inner cavity of the slot 304. The bottom of the magnetic block 305 is fixedly connected to the tray 2, and the top of the magnetic block 305 is adsorbed and connected to the magnetic block 303.

[0026] Specifically: the storage slot 302 is used to store the culture dish, and the expansion plate 301 is made of medical-grade silicone, which can enhance the friction between the expansion plate 301 and the culture dish, ensuring that the culture dish does not shift during shaking. Multiple storage slots 302 can be set to simultaneously increase the area of ​​the expansion plate 301, which can shake multiple culture dishes at the same time, greatly improving work efficiency. There are multiple magnetic card blocks 303 and card slots 304, which provide precise positioning and guidance for the expansion plate 301. The adsorption force between the magnetic block 305 and the magnetic card block 303 further ensures the stability of the expansion plate 301 during operation. Example 2

[0027] Please see Figure 1-5 Based on Embodiment 1, the shaking mechanism 4 includes a drive motor 401. One side of the drive motor 401 is fixedly connected to the housing 1. A turntable 402 is fixedly connected to the output end of the drive motor 401. A fixed rod 403 is slidably connected to the surface of the turntable 402. A lead screw 404 is threaded to one end of the fixed rod 403. A micro motor 405 is fixedly connected to one side of the lead screw 404, which passes through the inner cavity of the turntable 402. One side of the micro motor 405 is fixedly connected to the turntable 402. A connecting rod 406 is movably connected to the other end of the fixed rod 403. A toothed plate 407 is movably connected to the other end of the connecting rod 406. The bottom of the toothed plate 407 is slidably connected to the housing 1. A gear 408 meshes with the top of the toothed plate 407. A gear 408 is fixedly connected to the inner side of the gear 408. A rotating rod 409 is connected to a tray 2. Both sides of the rotating rod 409 are rotatably connected to the box body 1. A control panel 5 is provided on one side of the rotating rod 409. One side of the control panel 5 is fixedly connected to the box body 1. A slide rail 6 is slidably connected to the bottom of the toothed plate 407. The bottom of the slide rail 6 is fixedly connected to the box body 1. Limit rings 7 are provided on both sides of the connecting rod 406. The inner side of the limit ring 7 is fixedly connected to the fixed rod 403. A shock-absorbing pad 8 is fixedly connected to the bottom of the box body 1. A rubber column 9 is fixedly connected to the bottom of the shock-absorbing pad 8. A slider 10 is fixedly connected to one end of the fixed rod 403. A groove 11 is opened on the surface of the turntable 402. One side of the slider 10 is slidably connected to the groove 11. The inner side of the slider 10 is threadedly connected to the lead screw 404.

[0028] Specifically: the lead screw 404 is rotatably connected to the turntable 402 on the other side, which can improve the stability of the lead screw 404 during operation. The micro motor 405 can quickly change the shaking amplitude of the tray 2 without complicated disassembly or additional tools. Experimenters can flexibly adjust it according to different cell culture stages and experimental requirements. The control panel 5 is equipped with time setting buttons, speed setting buttons and start buttons. For different types of dishes, more precise speed can be set to ensure that the cells are shaken evenly while avoiding liquid splashing and contamination. The slide rail 6 provides precise guidance and limit for the toothed plate 407. There are two limit rings 7, which can limit the range of motion of the connecting rod 406. The shock-absorbing pad 8 and the rubber column 9 form a double-layer shock-absorbing structure, which can effectively absorb the vibration generated by the shaking mechanism 4 during operation. The cooperation between the slider 10 and the slide groove 11 provides precise guidance for the sliding of the fixed rod 403 on the turntable 402.

[0029] The working principle of this utility model is as follows: In use, the magnetic card block 303 on the extension plate 301 is aligned with the card slot 304 on the tray 2 and inserted. After insertion, the magnetic block 305 attracts the magnetic card block 303. Then, the petri dish is placed in the storage tank 302. The speed and running time of the drive motor 401 are adjusted by the speed setting button and time setting button on the control panel 5. When it is necessary to adjust the shaking amplitude, the micro motor 405 starts and drives the lead screw 404 to rotate. The lead screw 404 drives the slider 10 to move along the slide groove 11 and towards the turntable 4. As the center of the tray 2 moves closer to the slider 10, the fixed rod 403 moves with the slider 10. The center distance between the connecting rod 406 and the turntable 402 is adjusted to change the shaking amplitude of the tray 2. After adjustment, the drive motor 401 starts and drives the turntable 402 to rotate. The turntable 402 drives the fixed rod 403 to rotate. The fixed rod 403 drives the connecting rod 406 to pull the toothed plate 407 back and forth. The toothed plate 407 moves along the slide rail 6 and drives the gear 408 to rotate. The gear 408 drives the rotating rod 409 to rotate. The rotating rod 409 drives the tray 2 to shake back and forth, thereby shaking the culture dish evenly.

[0030] The preferred embodiments of the present utility model disclosed above are only used to help illustrate the present utility model. The preferred embodiments do not describe all the details in detail, nor do they limit the present utility model to the specific implementation methods described. The present specification selects and specifically describes these embodiments in order to better explain the principle and practical application of the present utility model, so that those skilled in the art can better understand and utilize the present utility model.

Claims

1. A cell culture dish shaking device, comprising a housing (1), characterized in that: The top of the box (1) is provided with a tray (2), the top of the tray (2) is movably connected with a locking mechanism (3), and the inner cavity of the box (1) is fixedly connected with a shaking mechanism (4). The locking mechanism (3) includes an extension plate (301) located on top of the tray (2). The extension plate (301) has a storage slot (302) on top. Magnetic card blocks (303) are fixedly connected to both sides of the bottom of the extension plate (301). The tray (2) has a card slot (304) on top. The bottom of the magnetic card block (303) is slidably connected to the card slot (304). A magnetic suction block (305) is provided in the inner cavity of the card slot (304). The bottom of the magnetic suction block (305) is fixedly connected to the tray (2), and the top of the magnetic suction block (305) is attracted to the magnetic card block (303).

2. The cell culture dish shaking device according to claim 1, characterized in that: The shaking mechanism (4) includes a drive motor (401), one side of which is fixedly connected to the housing (1). A turntable (402) is fixedly connected to the output end of the drive motor (401). A fixed rod (403) is slidably connected to the surface of the turntable (402). A lead screw (404) is threaded to one end of the fixed rod (403). A micro motor (405) is fixedly connected to one side of the lead screw (404) through the inner cavity of the turntable (402). The micro motor (405) is connected to the turntable (402) on one side. The plate (402) is fixedly connected, and the other end of the fixed rod (403) is movably connected to the connecting rod (406). The other end of the connecting rod (406) is movably connected to the toothed plate (407). The bottom of the toothed plate (407) is slidably connected to the box body (1). The top of the toothed plate (407) is meshed with a gear (408). The inner side of the gear (408) is fixedly connected to the rotating rod (409). The surface of the rotating rod (409) is fixedly connected to the tray (2). Both sides of the rotating rod (409) are rotatably connected to the box body (1).

3. The cell culture dish shaking device according to claim 2, characterized in that: A control panel (5) is provided on one side of the rotating rod (409), and one side of the control panel (5) is fixedly connected to the box body (1).

4. The cell culture dish shaking device according to claim 2, characterized in that: The bottom of the toothed plate (407) is slidably connected to a slide rail (6), and the bottom of the slide rail (6) is fixedly connected to the box body (1).

5. The cell culture dish shaking device according to claim 2, characterized in that: Limiting rings (7) are provided on both sides of the connecting rod (406), and the inner side of the limiting rings (7) is fixedly connected to the fixing rod (403).

6. The cell culture dish shaking device according to claim 1, characterized in that: The bottom of the box (1) is fixedly connected to a shock-absorbing pad (8), and the bottom of the shock-absorbing pad (8) is fixedly connected to a rubber column (9).

7. The cell culture dish shaking device according to claim 2, characterized in that: One end of the fixed rod (403) is fixedly connected to a slider (10), and a groove (11) is provided on the surface of the turntable (402). One side of the slider (10) is slidably connected to the groove (11), and the inner side of the slider (10) is threadedly connected to the lead screw (404).

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