Traditional Chinese medicine extraction liquid-gas separation type concentration rectification integrated device

Abstract

The application relates to the technical field of traditional Chinese medicine extraction, and discloses a traditional Chinese medicine extract gas-liquid separation type concentration and rectification integrated device which comprises a traditional Chinese medicine extract conveying pump, a preheating heat exchanger, a climbing film evaporator, a gas-liquid separator I, a concentrated liquid conveying pump, an evaporation crystallization dryer, a gas-liquid separator II, a rectification tower, a condenser and a steam generator. The suction end of the traditional Chinese medicine extract conveying pump is fixedly connected with a traditional Chinese medicine extract conveying pipe, the discharge end of the traditional Chinese medicine extract conveying pump is fixedly and communicatively connected with the liquid inlet end of the preheating heat exchanger through a pipeline, and the liquid outlet end of the preheating heat exchanger is fixedly connected with the liquid inlet end of the climbing film evaporator through a pipeline. The application has the following advantages and effects: the continuous and efficient concentration of the traditional Chinese medicine extract and the high-purity recovery of the solvent are realized, the production efficiency is greatly improved, the product quality is stable, the overall energy consumption is greatly reduced through the secondary utilization of steam waste heat, and the high-efficiency energy-saving effect is achieved.

Description

Technical Field

[0001] This application relates to the field of traditional Chinese medicine extraction technology, and in particular to an integrated device for gas-liquid separation, concentration and distillation of traditional Chinese medicine extract. Background Technology

[0002] Traditional Chinese medicine (TCM) contains a highly complex chemical composition, typically including sugars, amino acids, proteins, oils, waxes, enzymes, pigments, vitamins, organic acids, tannins, inorganic salts, volatile oils, alkaloids, and glycosides. It contains multiple effective components, as well as ineffective and toxic components. TCM extraction utilizes techniques to maximize the extraction of these effective components, thereby improving the intrinsic quality and clinical efficacy of TCM preparations and maximizing their therapeutic effects. Currently, commonly used TCM extraction methods include solvent extraction, steam distillation, sublimation, ultrasound-assisted extraction, microwave-assisted extraction, solid-phase extraction, and micro-extraction. Solvent extraction, based on the different solubilities of various components in TCM, selects solvents with high solubility for effective components and low solubility for components not requiring extraction, thus dissolving the effective components from the medicinal tissue cells as much as possible. This method is widely used for the extraction of bioactive compounds from plant-derived medicinal materials.

[0003] Concentration is an essential and energy-intensive step in the pharmaceutical process of traditional Chinese medicine (TCM). Concentration of extracts involves purifying and concentrating the active ingredients to obtain a high-concentration TCM liquid for further processing into oral liquids or powders (capsules, granules, tablets). Currently, these pretreatments of TCM materials are mainly achieved using multifunctional TCM extraction and concentration machines. Existing TCM extraction and concentration machines operate intermittently, failing to effectively recover and utilize the heat energy generated during extraction or concentration, or their recovery systems are complex, leading to energy waste. Furthermore, intermittent operation is inefficient, increasing the time required for concentration, and prolonged boiling can damage the active ingredients of the TCM. Therefore, we propose a method and apparatus for continuous concentration of TCM extracts coupled with solvent recovery.

[0004] Therefore, we propose an integrated gas-liquid separation, concentration, and distillation device for traditional Chinese medicine extracts to solve the above problems. Utility Model Content

[0005] The purpose of this application is to provide an integrated gas-liquid separation, concentration, and distillation device for traditional Chinese medicine extracts. This device achieves continuous and efficient concentration of the extracts and high-purity recovery of the solvent, significantly improving production efficiency and ensuring stable product quality. Furthermore, it greatly reduces overall energy consumption through the secondary utilization of waste heat from steam, thus achieving high efficiency and energy saving.

[0006] The above-mentioned technical objective of this application is achieved through the following technical solution: an integrated device for gas-liquid separation, concentration, and distillation of traditional Chinese medicine extract, comprising a traditional Chinese medicine extract delivery pump, a preheating heat exchanger, a rising film evaporator, a gas-liquid separator I, a concentrate delivery pump, an evaporation crystallization dryer, a gas-liquid separator II, a distillation column, a condenser, and a steam generator. The suction end of the traditional Chinese medicine extract delivery pump is fixedly connected to a traditional Chinese medicine extract delivery pipe. The discharge end of the traditional Chinese medicine extract delivery pump is fixedly connected to the liquid inlet end of the preheating heat exchanger via a pipe. The liquid outlet end of the preheating heat exchanger is fixedly connected to the liquid inlet end of the rising film evaporator via a pipe. The steam outlet end of the rising film evaporator is connected to the gas-liquid separator I... The steam inlet is fixedly connected via a pipeline. The liquid outlet of the rising film evaporator and the liquid outlet of the first gas-liquid separator are both fixedly connected via pipelines to the suction end of the concentrate delivery pump. The discharge end of the concentrate delivery pump is fixedly connected via a pipeline to the liquid inlet of the evaporative crystallizer dryer. The steam outlet of the first gas-liquid separator and the steam outlet of the evaporative crystallizer dryer are both fixedly connected via pipelines to the steam inlet of the second gas-liquid separator. The steam outlet of the second gas-liquid separator is fixedly connected to the steam inlet of the distillation column. The steam outlet of the distillation column is fixedly connected to a distillation gas discharge pipe. The end of the distillation gas discharge pipe away from the distillation column is fixedly connected to the steam inlet of the condenser. The liquid outlet of the condenser is fixedly connected to a condensate discharge pipe.

[0007] A further configuration of this application is as follows: the steam generator is fixedly connected to a steam main pipe at its steam outlet, and a steam branch pipe 1 and a steam branch pipe 2 are fixedly connected to the steam main pipe. The end of the steam branch pipe 1 that is away from the steam main pipe is fixedly connected to the steam inlet of the rising film evaporator, and the end of the steam branch pipe 2 that is away from the steam main pipe is fixedly connected to the steam inlet of the evaporation crystallization dryer.

[0008] A further configuration of this application is as follows: the steam condensate discharge end of the rising film evaporator is fixedly connected to a steam condensate delivery pipe one; the steam condensate discharge end of the evaporative crystallizer is fixedly connected to a steam condensate delivery pipe two; the end of the steam condensate delivery pipe two away from the evaporative crystallizer is fixedly connected to the steam condensate delivery pipe one; the end of the steam condensate delivery pipe one away from the rising film evaporator is fixedly connected to the steam inlet end of the preheating heat exchanger; and the steam discharge end of the preheating heat exchanger is fixedly connected to a steam condensate delivery main pipe.

[0009] A further feature of this application is that a high-concentration drug solution collection cabinet is provided on one side of the evaporation crystallization dryer, and a high-concentration drug solution discharge pipe is fixedly connected to the discharge end of the evaporation crystallization dryer. The end of the high-concentration drug solution discharge pipe away from the evaporation crystallization dryer is fixedly connected to the high-concentration drug solution collection cabinet.

[0010] A further feature of this application is that a liquid discharge pipe is fixedly connected to the liquid outlet end of the gas-liquid separator II.

[0011] A further feature of this application is that a low-temperature water inlet pipe is fixedly connected to the water inlet end of the condenser, and a high-temperature water outlet pipe is fixedly connected to the water outlet end of the condenser.

[0012] This application includes at least one of the following beneficial technical effects:

[0013] This application utilizes the synergistic effect of a traditional Chinese medicine extract transfer pump, a preheating heat exchanger, a rising film evaporator, a gas-liquid separator (I), a concentrate transfer pump, an evaporative crystallizer dryer, a gas-liquid separator (II), a distillation column, a condenser, and a steam generator. This achieves continuous and efficient concentration of the traditional Chinese medicine extract and high-purity recovery of the solvent. Furthermore, it significantly reduces overall energy consumption through the secondary utilization of waste heat from the steam, achieving a high efficiency and energy-saving effect. Moreover, the continuous feeding and discharging method for concentrating the traditional Chinese medicine extract greatly improves production efficiency and ensures stable product quality. Attached Figure Description

[0014] Figure 1 This is a schematic diagram of the main view structure of this embodiment.

[0015] In the diagram, 1. Traditional Chinese medicine extract transfer pump; 2. Preheating heat exchanger; 3. Rising film evaporator; 4. Gas-liquid separator I; 5. Concentrate transfer pump; 6. Evaporation crystallization dryer; 7. Gas-liquid separator II; 8. Distillation column; 9. Condenser; 10. Distillation gas discharge pipe; 11. Condensate discharge pipe; 12. Traditional Chinese medicine extract transfer pipe; 13. Steam generator; 14. Steam main pipe; 15. Steam branch pipe I; 16. Steam branch pipe II; 17. Steam condensate transfer pipe I; 18. Steam condensate transfer pipe II; 19. High-concentration medicine collection cabinet; 20. High-concentration medicine discharge pipe; 21. Liquid discharge pipe; 22. Low-temperature water inlet pipe; 23. High-temperature water outlet pipe; 24. Steam condensate transfer main pipe. Detailed Implementation

[0016] The technical solution of this application will be clearly and completely described below with reference to specific embodiments. Obviously, the described embodiments are only a part of the embodiments of this application, and not all of them. All other embodiments obtained by those skilled in the art based on the embodiments of this application without creative effort are within the scope of protection of this application.

[0017] See Figure 1This application provides an integrated gas-liquid separation, concentration, and distillation device for traditional Chinese medicine extracts, comprising a traditional Chinese medicine extract delivery pump 1, a preheating heat exchanger 2, a rising film evaporator 3, a gas-liquid separator 4, a concentrate delivery pump 5, an evaporation crystallization dryer 6, a gas-liquid separator 7, a distillation column 8, a condenser 9, and a steam generator 13. The suction end of the traditional Chinese medicine extract delivery pump 1 is fixedly connected to a traditional Chinese medicine extract delivery pipe 12, which is used to transport the traditional Chinese medicine extract to be concentrated and distilled. The traditional Chinese medicine extract delivery pump 1 can pump the traditional Chinese medicine extract to be concentrated and distilled to the preheating heat exchanger 2 for preheating treatment. The discharge end of the traditional Chinese medicine extract delivery pump 1... The outlet end of the preheating heat exchanger 2 is fixedly connected to the inlet end of the preheating heat exchanger 2 via a pipe. The outlet end of the preheating heat exchanger 2 is fixedly connected to the inlet end of the rising film evaporator 3 via a pipe. The steam outlet end of the rising film evaporator 3 is fixedly connected to the steam inlet end of the gas-liquid separator 4 via a pipe. The gas-liquid separator 4 is used to separate the solvent vapor and the concentrated Chinese medicine liquid obtained by the rising film evaporator 3. The outlet ends of the rising film evaporator 3 and the gas-liquid separator 4 are both fixedly connected to the suction end of the concentrate transfer pump 5 via pipes. The discharge end of the concentrate transfer pump 5 is fixedly connected to the inlet end of the evaporation crystallizer dryer 6 via a pipe. The concentrate transfer pump 5 can be used to transfer the rising film evaporator... The concentrated Chinese medicine liquid in separator 3 and gas-liquid separator 4 is pumped to evaporation crystallization dryer 6. Evaporation crystallization dryer 6 is used to further concentrate the concentrated Chinese medicine liquid entering it and to further remove moisture from the high-concentration liquid. The steam outlets of gas-liquid separator 4 and evaporation crystallization dryer 6 are fixedly connected to the steam inlet of gas-liquid separator 7 through pipelines, so that the solvent vapor discharged from evaporation crystallization dryer 6 and the solvent vapor discharged from gas-liquid separator 4 can be mixed and then enter gas-liquid separator 7. Gas-liquid separator 7 is used to further separate the mixed solvent vapor. The steam outlet of gas-liquid separator 7 is connected to the steam inlet of distillation column 8. The distillation column 8 is fixedly connected to the end of the condenser 9. It is used to distill the solvent vapor after further gas-liquid separation. Through distillation, the effective components and impurities are accurately separated. The steam outlet end of the distillation column 8 is fixedly connected to the distillation vapor discharge pipe 10. The end of the distillation vapor discharge pipe 10 away from the distillation column 8 is fixedly connected to the steam inlet end of the condenser 9. The distillation vapor discharge pipe 10 is used to guide the distilled solvent vapor into the condenser 9 for condensation treatment to obtain high-purity solvent distillate. The liquid outlet end of the condenser 9 is fixedly connected to the condensate discharge pipe 11. The condensate discharge pipe 11 is used to discharge the obtained solvent distillate, thereby achieving efficient and comprehensive solvent recovery.

[0018] In this embodiment, a steam main pipe 14 is fixedly connected to the steam outlet of the steam generator 13. A steam branch pipe 15 and a steam branch pipe 16 are fixedly connected to the steam main pipe 14. The end of the steam branch pipe 15 away from the steam main pipe 14 is fixedly connected to the steam inlet of the rising film evaporator 3. The end of the steam branch pipe 16 away from the steam main pipe 14 is fixedly connected to the steam inlet of the evaporation crystallization dryer 6. The steam generator 13 is used to produce steam. The design of the steam main pipe 14 and the steam branch pipes 15 and 16 allows for the diversion and transportation of steam, so that part of the steam enters the rising film evaporator 3 and the other part of the steam enters the evaporation crystallization dryer 6. The steam entering the rising film evaporator 3 can be used to heat and concentrate the traditional Chinese medicine extract, and the steam entering the evaporation crystallization dryer 6 can be used to reheat and concentrate the high-concentration traditional Chinese medicine liquid.

[0019] In this embodiment, the steam condensate discharge end of the rising film evaporator 3 is fixedly connected to a steam condensate delivery pipe 17, and the steam condensate discharge end of the evaporative crystallizer dryer 6 is fixedly connected to a steam condensate delivery pipe 18. The end of the steam condensate delivery pipe 18 furthest from the evaporative crystallizer dryer 6 is fixedly connected to the steam condensate delivery pipe 17. The end of the steam condensate delivery pipe 17 furthest from the rising film evaporator 3 is fixedly connected to the steam inlet end of the preheating heat exchanger 2. The steam discharge end of the preheating heat exchanger 2 is fixedly connected to a steam condensate delivery main pipe 24, utilizing steam condensate delivery... Pipe 17 can transport the high-temperature steam condensate generated in the rising film evaporator 3 to the preheating heat exchanger 2. Pipe 28 can transport the high-temperature steam condensate generated in the evaporation crystallization dryer 6 to the preheating heat exchanger 2. Thus, the high-temperature steam condensate entering the preheating heat exchanger 2 can be used to preheat the Chinese herbal extract to be concentrated and distilled. The steam condensate main pipe 24 is used to discharge the steam condensate after releasing heat, thus realizing the full utilization of the waste heat of steam, greatly reducing the energy consumption of subsequent heating links, and having a high efficiency and energy saving effect.

[0020] In this embodiment, a high-concentration medicine liquid collection cabinet 19 is provided on one side of the evaporation crystallization dryer 6. A high-concentration medicine liquid discharge pipe 20 is fixedly connected to the discharge end of the evaporation crystallization dryer 6. The end of the high-concentration medicine liquid discharge pipe 20 away from the evaporation crystallization dryer 6 is fixedly connected to the high-concentration medicine liquid collection cabinet 19. The high-concentration medicine liquid discharge pipe 20 is used to guide the high-concentration traditional Chinese medicine liquid in the evaporation crystallization dryer 6 to the high-concentration medicine liquid collection cabinet 19. The high-concentration medicine liquid collection cabinet 19 is used to collect the high-concentration traditional Chinese medicine liquid.

[0021] In this embodiment, a liquid discharge pipe 21 is fixedly connected to the liquid outlet end of the gas-liquid separator 2 7. The liquid discharge pipe 21 is used to discharge the residual drug liquid in the gas-liquid separator 2 7.

[0022] In this embodiment, a low-temperature water inlet pipe 22 is fixedly connected to the water inlet end of the condenser 9, and a high-temperature water outlet pipe 23 is fixedly connected to the water outlet end of the condenser 9. The low-temperature water inlet pipe 22 is used to transport low-temperature cooling water to the condenser 9, thereby utilizing the low-temperature cooling water to absorb the heat in the distilled gas entering the condenser 9. The high-temperature water outlet pipe 23 is used to discharge the cooling water after heat absorption, thereby realizing the cooling and condensation treatment of the distilled gas.

[0023] With the above structure, the integrated gas-liquid separation concentration and distillation device for traditional Chinese medicine extract provided in this application, when in use, the traditional Chinese medicine extract to be processed enters the preheating heat exchanger 2 through the traditional Chinese medicine extract delivery pipe 12 under the pumping action of the traditional Chinese medicine extract delivery pump 1. During this process, the high-temperature steam condensate generated in the rising film evaporator 3 can be delivered to the preheating heat exchanger 2 by the steam condensate delivery pipe 17, and the high-temperature steam condensate generated in the evaporation crystallizer dryer 6 can also be delivered to the preheating heat exchanger 2 by the steam condensate delivery pipe 28. Thus, the high-temperature steam condensate entering the preheating heat exchanger 2 can be used to preheat the traditional Chinese medicine extract to be concentrated and distilled. After releasing heat, the steam condensate is discharged from the steam condensate delivery main pipe 24, thereby using the residual heat in the steam to preheat the traditional Chinese medicine extract, realizing the full utilization of the residual heat of the steam, and reducing energy consumption for the subsequent concentration stage.

[0024] The preheated herbal extract enters the rising film evaporator 3, where it evaporates rapidly under steam heating, forming a mixture of solvent vapor and concentrated herbal liquid. This mixture undergoes preliminary separation in the gas-liquid separator 4. The concentrated herbal liquid from the rising film evaporator 3 and the gas-liquid separator 4 is then pumped to the evaporative crystallizer dryer 6 using the concentrate transfer pump 5. The evaporative crystallizer dryer 6 further concentrates the entering herbal extract to remove more moisture. The high-concentration liquid after treatment in the evaporative crystallizer dryer 6 is collected in the high-concentration liquid collection tank 19 through the high-concentration liquid discharge pipe 20 for subsequent high-concentration liquid processing. While the liquid medicine is being processed, the solvent vapor separated by gas-liquid separator 4 and the solvent vapor generated by evaporation crystallization dryer 6 are combined and then enter gas-liquid separator 7 for secondary separation to further ensure that the solvent vapor does not contain any impurities from the liquid medicine. The pure solvent vapor after secondary separation then enters distillation column 8, where the effective components and impurities are accurately separated through distillation. The distilled solvent vapor enters condenser 9 through distillation gas discharge pipe 10, where it is condensed into high-purity solvent liquid under the action of low-temperature cooling water (supplied through low-temperature water inlet pipe 22) and finally discharged through condensate discharge pipe 11 for easy recovery.

Claims

1. A traditional Chinese medicine extraction liquid-gas separation type concentration rectification integrated device, characterized in that, The system includes a traditional Chinese medicine extract delivery pump (1), a preheating heat exchanger (2), a rising film evaporator (3), a gas-liquid separator (4), a concentrate delivery pump (5), an evaporation crystallization dryer (6), a gas-liquid separator (7), a distillation column (8), a condenser (9), and a steam generator (13). The suction end of the traditional Chinese medicine extract delivery pump (1) is fixedly connected to a traditional Chinese medicine extract delivery pipe (12). The discharge end of the traditional Chinese medicine extract delivery pump (1) is fixedly connected to the liquid inlet end of the preheating heat exchanger (2) through a pipe. The liquid outlet end of the preheating heat exchanger (2) is fixedly connected to the liquid inlet end of the rising film evaporator (3) through a pipe. The steam outlet end of the rising film evaporator (3) is fixedly connected to the steam inlet end of the gas-liquid separator (4) through a pipe. The liquid outlet end of the rising film evaporator (3) and the gas-liquid separator (4) are connected to each other through a pipe. The liquid outlet of separator one (4) is fixedly connected to the suction end of the concentrate delivery pump (5) through a pipe. The discharge end of the concentrate delivery pump (5) is fixedly connected to the liquid inlet of the evaporation crystallizer (6) through a pipe. The steam outlet of the gas-liquid separator one (4) and the steam outlet of the evaporation crystallizer (6) are fixedly connected to the steam inlet of the gas-liquid separator two (7) through a pipe. The steam outlet of the gas-liquid separator two (7) is fixedly connected to the steam inlet of the distillation column (8). The steam outlet of the distillation column (8) is fixedly connected to a distillation gas discharge pipe (10). The end of the distillation gas discharge pipe (10) away from the distillation column (8) is fixedly connected to the steam inlet of the condenser (9). The liquid outlet of the condenser (9) is fixedly connected to a condensate discharge pipe (11).

2. The integrated gas-liquid separation, concentration, and distillation device for traditional Chinese medicine extracts according to claim 1, characterized in that: The steam generator (13) is fixedly connected to a steam main pipe (14) at its steam outlet. A steam branch pipe (15) and a steam branch pipe (16) are fixedly connected to the steam main pipe (14). The end of the steam branch pipe (15) away from the steam main pipe (14) is fixedly connected to the steam inlet of the rising film evaporator (3). The end of the steam branch pipe (16) away from the steam main pipe (14) is fixedly connected to the steam inlet of the evaporation crystallizer (6).

3. The integrated gas-liquid separation, concentration, and distillation device for traditional Chinese medicine extracts according to claim 2, characterized in that: The steam condensate discharge end of the rising film evaporator (3) is fixedly connected to a steam condensate delivery pipe one (17), the steam condensate discharge end of the evaporation crystallizer (6) is fixedly connected to a steam condensate delivery pipe two (18), the end of the steam condensate delivery pipe two (18) away from the evaporation crystallizer (6) is fixedly connected to the steam condensate delivery pipe one (17), the end of the steam condensate delivery pipe one (17) away from the rising film evaporator (3) is fixedly connected to the steam inlet end of the preheating heat exchanger (2), and the steam discharge end of the preheating heat exchanger (2) is fixedly connected to a steam condensate delivery main pipe (24).

4. The integrated device for concentrating and rectifying the traditional Chinese medicine extract by gas-liquid separation according to claim 1, characterized in that: A high-concentration drug liquid collection cabinet (19) is provided on one side of the evaporation crystallization dryer (6), and a high-concentration drug liquid discharge pipe (20) is fixedly connected to the discharge end of the evaporation crystallization dryer (6). The end of the high-concentration drug liquid discharge pipe (20) away from the evaporation crystallization dryer (6) is fixedly connected to the high-concentration drug liquid collection cabinet (19).

5. The integrated device for concentrating and rectifying the traditional Chinese medicine extract by gas-liquid separation according to claim 1, characterized in that: The liquid outlet end of the gas-liquid separator 2 (7) is fixedly connected to a liquid discharge pipe (21).

6. The integrated device for concentrating and rectifying the traditional Chinese medicine extract by gas-liquid separation according to claim 1, characterized in that: The condenser (9) is fixedly connected to a low-temperature water inlet pipe (22) at its inlet end and to a high-temperature water outlet pipe (23) at its outlet end.

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