A density detection phase separation device for pharmaceutical use

Abstract

This utility model relates to a density detection and phase separation device for pharmaceutical use, comprising an extraction tank, a first drain pipe connected to the bottom of the extraction tank, a mixing tank connected to the other end of the first drain pipe, a second drain pipe connected to the bottom of the mixing tank, a reflux pipe and a heavy phase pipe connected to the other end of the second drain pipe via an electric three-way valve, and the other end of the reflux pipe connected to the upper part of the extraction tank. A first density detector, a sight glass, and a manual ball valve are sequentially arranged on the first drain pipe in the direction of discharge. A second density detector is arranged on the second drain pipe. Warning lights are provided on the surfaces of both the first and second density detectors. The second density detector and the electric three-way valve are electrically connected via a controller. This utility model can perform fine phase separation on mixed solutions, separating out the heavy phase solution and allowing the light phase solution mixed in the heavy phase solution to flow back into the extraction tank for purification of the heavy phase solution. It achieves high phase separation accuracy and significantly improves the recovery rate and quality of the feed solution.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical equipment technology, specifically to a density detection and phase separation device for pharmaceutical applications. Background Technology

[0002] In pharmaceutical manufacturing, extraction and phase separation is a crucial step. Its purpose is to separate the active ingredients from the mixed solution, thereby improving drug purity and quality. Traditionally, the extraction and phase separation process involves personnel observing the interior of the extraction vessel through a transparent microscope. Phase separation is then performed after a two-phase interface appears in the mixed solution inside the vessel.

[0003] However, the interface between the feed liquid and the waste liquid is not obvious after extraction. Relying on manual visual identification of the two-phase interface is prone to deviation, resulting in low phase separation accuracy and affecting the recovery rate and quality of the feed liquid. Utility Model Content

[0004] The purpose of this invention is to design a density detection and phase separation device for pharmaceutical use, which can solve the technical problems mentioned in the background art.

[0005] To achieve the above objectives, this utility model provides the following technical solution: A density detection and phase separation device for pharmaceutical use includes an extraction tank. The bottom of the extraction tank is connected to a first drain pipe, and the other end of the first drain pipe is connected to a mixing tank. The bottom of the mixing tank is connected to a second drain pipe, and the other end of the second drain pipe is connected to a reflux pipe and a heavy phase pipe via an electric three-way valve. The other end of the reflux pipe is connected to the upper part of the extraction tank. A first density detector, a sight glass, and a manual ball valve are sequentially arranged on the first drain pipe in the direction of discharge. A second density detector is arranged on the second drain pipe. Warning lights are provided on the surface of both the first and second density detectors. The second density detector and the electric three-way valve are electrically connected via a controller.

[0006] Furthermore, both the first density detector and the second density detector are equipped with alarms.

[0007] Furthermore, the upper part of the extraction tank is connected to a first gas pipe, and the upper part of the mixing tank is connected to a second gas pipe.

[0008] Furthermore, the end of the heavy phase pipe furthest from the electric three-way valve is connected to a heavy phase tank.

[0009] Furthermore, the upper part of the heavy phase tank is connected to a third gas pipe, and the bottom of the heavy phase tank is connected to a first unloading pipe.

[0010] Furthermore, a manual three-way valve is connected between the bottom of the extraction tank and the inlet of the first drain pipe, and the third port of the manual three-way valve is connected to a second discharge pipe.

[0011] The beneficial effects of this utility model are as follows: During the phase separation process of the mixed solution in the extraction tank, when the density of the solution flowing through the first drain pipe is less than the preset density threshold, the warning light of the first density detector will light up. The phase separation personnel will immediately close the manual ball valve and wait for the warning light of the first density detector to go out before opening the manual ball valve again. By controlling the manual ball valve, fine phase separation is performed, which has high phase separation accuracy and improves the recovery rate and quality of the feed liquid. The heavy phase solution separated from the mixed solution flows into the mixing tank for further phase separation. When the second density detector detects that the density of the solution flowing through the second drain pipe is greater than the preset density threshold, the controller will activate the electric three-way valve to connect the second drain pipe with the heavy phase pipe, making it easier to separate the heavy phase solution. When the second density detector detects that the density of the solution flowing through the second drain pipe is less than the preset density threshold, the controller will activate the electric three-way valve to connect the second drain pipe with the return pipe, returning the light phase solution mixed in the heavy phase solution to the extraction tank for purification of the heavy phase solution, further improving the phase separation accuracy and increasing the recovery rate and quality of the feed solution. Attached Figure Description

[0012] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0013] Figure 1 This is a schematic diagram of the structure of this utility model.

[0014] The names of the components shown in the diagram are as follows: 1. Extraction tank; 2. First drain pipe; 3. Mixing tank; 4. Second drain pipe; 5. Electric three-way valve; 6. Reflux pipe; 7. Heavy phase pipe; 8. First density meter; 9. Sight glass; 10. Manual ball valve; 11. Second density meter; 12. Warning light; 13. First gas pipe; 14. Second gas pipe; 15. Heavy phase tank; 16. Third gas pipe; 17. First unloading pipe; 18. Manual three-way valve; 19. Second unloading pipe. Detailed Implementation

[0015] To further illustrate the technical means and effects adopted by this utility model in order to achieve the intended utility model purpose, the following detailed description of the specific implementation methods, structure, features and effects of this utility model is provided in conjunction with the accompanying drawings and preferred embodiments.

[0016] like Figure 1 As shown, a density detection phase separation device for pharmaceutical use includes an extraction tank 1. The bottom of the extraction tank 1 is connected to a first drain pipe 2 and a second discharge pipe 19 via a manual three-way valve 18. By manually controlling the manual three-way valve 18, the extraction tank 1 can be connected to the first drain pipe 2 for phase separation, or connected to the second discharge pipe 19 for discharge. The other end of the first drain pipe 2 is connected to a mixing tank 3. The heavy phase solution separated from the mixed solution in the extraction tank 1 flows into the mixing tank 3 through the first drain pipe 2. The bottom of the mixing tank 3 is connected to a second drain pipe 4. The other end of the second drain pipe 4 is connected to a return pipe via an electric three-way valve 5. The second drain pipe 4 and the reflux pipe 7 connect the second drain pipe 4 to the reflux pipe 6. The other end of the reflux pipe 6 is connected to the upper part of the extraction tank 1. When the second drain pipe 4 and the reflux pipe 6 are connected, the light phase solution mixed in the heavy phase solution is returned to the extraction tank 1 through the reflux pipe 6. The other end of the heavy phase pipe 7 is connected to the heavy phase tank 15. When the second drain pipe 4 and the heavy phase pipe 7 are connected, the heavy phase solution flows into the heavy phase tank 15 for storage. The first drain pipe 2 is equipped with a first density detector 8, a sight glass 9, and a manual ball valve 10 in sequence in the drain direction. The first density detector 8 is used to detect the density of the solution flowing through the first drain pipe 2, and the sight glass 9 is used to observe the first drain pipe. The liquid in the liquid pipe 2 is used to monitor the phase separation of the solution, and to perform fine phase separation by manually controlling the ball valve 10. A second density detector 11 is installed on the second drain pipe 4 to detect the density of the solution flowing through it. Both the first density detector 8 and the second density detector 11 are equipped with warning lights 12, and both have internal alarms. The dual warning lights and alarms significantly improve the alerting effect for personnel involved in phase separation. The second density detector 11 and the electric three-way valve 5 are electrically connected via a controller, and the second density detector 11 feeds back signals to the controller. The electric three-way valve 5 is started by controlling the controller; the upper part of the extraction tank 1 is connected to the first gas pipe 13, the upper part of the mixing tank 3 is connected to the second gas pipe 14, and the upper part of the heavy phase tank 15 is connected to the third gas pipe 16. By adding nitrogen through the first gas pipe 13, the second gas pipe 14, and the third gas pipe 16, the gas pressure inside the extraction tank 1, the mixing tank 3, and the heavy phase tank 15 is increased, thereby allowing the solution to be discharged; or by venting air through the first gas pipe 13, the second gas pipe 14, and the third gas pipe 16, the gas pressure inside the extraction tank 1, the mixing tank 3, and the heavy phase tank 15 is decreased, allowing the solution to be added; the bottom of the heavy phase tank 15 is connected to the first discharge pipe 17.

[0017] Working principle: like Figure 1 As shown, when the density detection phase separation device is in use, during the phase separation process of the mixed solution in the extraction tank 1, the phase separation personnel first control the manual three-way valve 18 to connect the extraction tank 1 with the first drain pipe 2 for phase separation operation. When the first density detector 8 detects that the density of the solution flowing through the first drain pipe 2 is less than the preset density critical value, the warning light detected by the first density detector 8 will light up and the alarm will sound. The phase separation personnel will immediately close the manual ball valve 10. After the warning light detected by the first density detector goes out and the alarm stops, the manual ball valve 10 will be opened again. By controlling the manual ball valve 10, fine phase separation is performed. The phase separation accuracy is high, which improves the recovery rate and quality of the liquid. The heavy phase solution separated from the mixed solution flows into the mixing tank 3 through the first drain pipe 2 for further phase separation. When the second density detector 11 detects that the density of the solution flowing through the second drain pipe 4 is greater than the preset density threshold, the controller will activate the electric three-way valve 5 to connect the second drain pipe 4 with the heavy phase pipe 7, allowing the heavy phase to easily flow into the heavy phase tank 15 for storage. When the second density detector 11 detects that the density of the solution flowing through the second drain pipe 4 is less than the preset density threshold, the controller will activate the electric three-way valve 5 to connect the second drain pipe 4 with the return pipe 6, returning the light phase solution mixed in the heavy phase solution to the extraction tank 1 for purification of the heavy phase solution, further improving the phase separation accuracy and increasing the recovery rate and quality of the feed solution.

[0018] The above description is merely a preferred embodiment of the present utility model and is not intended to limit the present utility model in any way. Although the present utility model has been disclosed above with reference to a preferred embodiment, it is not intended to limit the present utility model. Any person skilled in the art can make some modifications or alterations to the above-disclosed technical content to create equivalent embodiments without departing from the scope of the present utility model. Any simple modifications, equivalent changes, and modifications made to the above embodiments based on the technical essence of the present utility model without departing from the scope of the present utility model shall still fall within the scope of the present utility model.

Claims

1. A density detection and phase separation device for pharmaceutical use, comprising an extraction tank (1), characterized in that, The bottom of the extraction tank (1) is connected to the first drain pipe (2), the other end of the first drain pipe (2) is connected to the mixing tank (3), the bottom of the mixing tank (3) is connected to the second drain pipe (4), the other end of the second drain pipe (4) is connected to the reflux pipe (6) and the heavy phase pipe (7) respectively through the electric three-way valve (5), the other end of the reflux pipe (6) is connected to the upper part of the extraction tank (1), the first drain pipe (2) is provided with a first density detector (8), a sight glass (9) and a manual ball valve (10) in sequence in the direction of draining, the second drain pipe (4) is provided with a second density detector (11), the surface of the first density detector (8) and the second density detector (11) are both provided with warning lights (12), the second density detector (11) and the electric three-way valve (5) are electrically connected through the controller.

2. The density detection and phase separation device for pharmaceutical use according to claim 1, characterized in that, Both the first density detector (8) and the second density detector (11) are equipped with alarms.

3. The density detection and phase separation device for pharmaceutical use according to claim 1, characterized in that, The upper part of the extraction tank (1) is connected to the first gas pipe (13), and the upper part of the mixing tank (3) is connected to the second gas pipe (14).

4. The density detection and phase separation device for pharmaceutical use according to claim 1, characterized in that, The end of the heavy phase tube (7) away from the electric three-way valve (5) is connected to the heavy phase tank (15).

5. The density detection and phase separation device for pharmaceutical use according to claim 4, characterized in that, The upper part of the heavy phase tank (15) is connected to a third gas pipe (16), and the bottom of the heavy phase tank (15) is connected to a first unloading pipe (17).

6. The density detection and phase separation device for pharmaceutical use according to claim 1, characterized in that, A manual three-way valve (18) is connected between the bottom of the extraction tank (1) and the inlet of the first drain pipe (2), and the third port of the manual three-way valve (18) is connected to the second unloading pipe (19).

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