Disinfecting composition

JP2025024251AInactive Publication Date: 2025-02-20NOF CORP
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Patent Information

Application Number
JP2021210026
Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
Filing Date
2021-12-24
Publication Date
2025-02-20
Estimated Expiration
Not applicable · inactive patent

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【0008】 塗布後の皮膚のべたつきがなくかつしっとりとした使用感を提供し、さらに、塗布直後に電子機器(特に、キーボード)を使用する際の使用を円滑に行うことを提供できる消毒用組成物を提供することができる。 詳しくは、本発明の消毒用組成物を手指等に使用した使用者は、皮膚にべたつきがなくかつしっとりとした使用感を感じるとともに、さらに、塗布直後に電子機器(特に、キーボード)を使用する際には、電子機器の使用を円滑に行うことができる。

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Abstract

To provide a disinfecting composition which can provide a moist use feeling without stickiness of skin after application and can further provide smooth use of an electronic device when using a keyboard of an electronic device or the like immediately after application to the skin such as fingers.SOLUTION: There is provided a disinfecting composition comprising a copolymer having a specific structure (P), a monovalent alcohol having 1 to 5 carbon atoms and a fatty acid triglyceride, which can provide a moist use feeling without stickiness of skin after application and can further provide smooth use feeling of an electronic device (especially, a keyboard) immediately after application.SELECTED DRAWING: None
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Description

[Technical field]

[0001] The present invention relates to a disinfectant composition, in particular, a disinfectant composition for use before the use of electronic devices, and more particularly, to a disinfectant composition for smoothly using electronic devices (particularly keyboards) immediately after application to the skin. [Background technology]

[0002] In recent years, there has been concern about the spread of infectious diseases caused by pathogenic viruses and bacteria, and various infection prevention related products have been developed. Disinfecting compositions have the advantage that they can sterilize and disinfect hands and fingers simply by applying them, and are therefore widely used. Disinfecting compositions contain a high content of monohydric alcohols having 1 to 5 carbon atoms, such as ethanol, in order to maintain the bactericidal power and improve the feeling of use, such as quick drying and non-stickiness, and are further devised by adjusting the type of thickener and the pH of the composition to a specific range. For example, a gel-type hand disinfectant has been proposed in which a carboxyvinyl polymer is neutralized with an alkali metal hydroxide and a polyethylene glycol having a specific molecular weight is used to prevent the composition from becoming cloudy (Patent Document 1). However, since the disinfectant composition does not have a neutral pH range and contains a relatively large amount of a monohydric alcohol having 1 to 5 carbon atoms, there is a risk of causing rough hands in those who use the disinfectant composition frequently, such as medical personnel.

[0003] Further innovations are known for imparting an anti-chapped hand effect to a disinfectant composition, such as blending a moisturizer such as glycerin, propylene glycol, or sorbitol (Patent Document 2), blending a water-soluble polyhydric alcohol and a fatty acid triglyceride (Patent Document 3), or blending an MPC copolymer and a maleic anhydride-containing polymer (Patent Document 4). The innovations proposed in the above patent documents have made it possible to provide a disinfectant composition that is non-sticky and provides a moist feel when used. [Prior art documents] [Patent documents]

[0004] [Patent Document 1] JP 2011-144146 A [Patent Document 2] JP 2004-155712 A [Patent Document 3] JP 2011-219410 A [Patent Document 4] JP 2008-115125 A Summary of the Invention [Problem to be solved by the invention]

[0005] When a disinfectant composition having a moist feel is used, if an electronic device (keyboard) such as an electronic medical record system is used immediately after the use, the keyboard becomes sticky and difficult to use. Doctors and nurses working in medical institutions have a strong demand for a disinfectant composition that allows smooth use of the keyboard even immediately after application to the skin. Therefore, an object of the present invention is to provide a disinfecting composition that provides a moist feeling without stickiness on the skin after application, and further enables smooth use of the keyboard of an electronic device, etc., immediately after application to the skin of the hands, fingers, etc. [Means for solving the problem]

[0006] As a result of intensive research into solving the above problems, the present inventors have confirmed that a disinfecting composition containing a copolymer (P) having a specific structure, a monohydric alcohol having 1 to 5 carbon atoms, and a fatty acid triglyceride provides a moist feeling of use without stickiness on the skin after application, and further provides a smooth feeling of use when using an electronic device (particularly, a keyboard) immediately after application, and have found that the above problems can be solved, thereby completing the present invention.

[0007] That is, the present invention relates to the following. 1.(1) 0.001% by mass to 10% by mass of a copolymer (P) having a weight average molecular weight of 1,000 to 1,000,000, comprising a structural unit (1) based on 2-(meth)acryloyloxyethyl phosphorylcholine represented by the following formula (1) and a structural unit (2) based on an alkyl group-containing (meth)acrylic monomer represented by the following formula (2), the content ratio of the structural unit (1) to the structural unit (2) being 15:85 to 45:55 in molar ratio; (2) 55% to 90% by mass of a monohydric alcohol having 1 to 5 carbon atoms, and (3) Fatty acid triglyceride: 0.001% by mass to 1% by mass 1. A disinfecting composition comprising: [ka] (In formula (1), R 1 represents a hydrogen atom or a methyl group.) [ka] (In formula (2), R 2 represents a hydrogen atom or a methyl group, and R 3 represents an alkyl group having 4 to 22 carbon atoms. 2. The disinfecting composition according to the preceding paragraph 1, wherein the monohydric alcohol having 1 to 5 carbon atoms is one or more selected from the group consisting of ethanol and isopropanol. 3. The disinfecting composition according to any one of items 1 to 2 above, wherein the fatty acid triglyceride is one or more selected from the group consisting of glyceryl triisooctanoate and glyceryl tricaprylate. 4. The disinfecting composition according to any one of the preceding items 1 to 3, further comprising an organic acid. Effect of the Invention

[0008] It is possible to provide a disinfecting composition which provides a moist feeling on the skin without stickiness after application, and further enables smooth use of an electronic device (particularly, a keyboard) immediately after application. Specifically, a user who applies the disinfecting composition of the present invention to his / her hands or fingers feels a non-sticky and moist sensation on the skin, and further, when using an electronic device (especially a keyboard) immediately after application, the electronic device can be used smoothly. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0009] The present invention will be described in detail below. The disinfecting composition of the present invention comprises: (1) 0.001% by mass to 10% by mass of a copolymer (P) having a weight average molecular weight of 1,000 to 1,000,000, comprising a structural unit (1) based on 2-(meth)acryloyloxyethyl phosphorylcholine represented by formula (1) and a structural unit (2) based on an alkyl group-containing (meth)acrylic monomer represented by formula (2), the content ratio of the structural unit (1) to the structural unit (2) being 15:85 to 45:55 in molar ratio. (2) 55% by mass to 90% by mass of monohydric alcohol having 1 to 5 carbon atoms (3) Fatty acid triglyceride: 0.001% by mass to 1% by mass In the present invention, "(meth)acrylic" means acrylic or methacrylic (methacrylic), and "(meth)acryloyl" means acryloyl or methacryloyl (methacryloyl). In addition, in the present specification, when a preferred numerical range (for example, the range of the content or the weight average molecular weight) is described in stages, each lower limit and upper limit can be combined independently. For example, in the description "preferably 10 to 100, more preferably 20 to 90", "preferable lower limit: 10" and "more preferably upper limit: 90" can be combined to form "10 to 90".

[0010] The copolymer (P) (MPC copolymer) contained in the disinfecting composition of the present invention is a copolymer containing a constitutional unit based on 2-(meth)acryloyloxyethyl phosphorylcholine (MPC) and a constitutional unit based on an alkyl group-containing (meth)acrylic monomer.

[0011] The MPC-based constitutional unit is represented by the following formula (1).

[0012] [ka]

[0013] In the above formula (1), R 1 represents a hydrogen atom or a methyl group.

[0014] The structural unit based on the alkyl group-containing (meth)acrylic monomer is represented by the following formula (2). [ka]

[0015] In the above formula (2), R 2 represents a hydrogen atom or a methyl group, and R 3 represents an alkyl group having 4 to 22 carbon atoms.

[0016] In formula (2), R 3 is a straight-chain or branched alkyl group having 4 to 22 carbon atoms, and examples thereof include butyl, pentyl, hexyl, octyl, 2-ethylhexyl, decyl, dodecyl, tetradecyl, hexadecyl, octadecyl, docosyl, lauryl, tridecyl, and stearyl.

[0017] Therefore, examples of structural units based on the alkyl group-containing (meth)acrylic monomer represented by formula (2) include structural units based on butyl (meth)acrylate, 2-ethylhexyl (meth)acrylate, lauryl (meth)acrylate, tridecyl (meth)acrylate, stearyl (meth)acrylate, docosyl (meth)acrylate, etc., with butyl (meth)acrylate being particularly preferred.

[0018] In the copolymer (P), the ratio of the contents of the constituent units based on MPC to the constituent units based on alkyl group-containing (meth)acrylic monomers ([constituent units based on MPC]:[constituent units based on alkyl group-containing (meth)acrylic monomers]) is, in molar ratio, 15:85 to 45:55, preferably 20:80 to 40:60, and more preferably 25:75 to 35:65.

[0019] The copolymer (P) may contain other structural units other than the structural units based on MPC and the structural units based on alkyl group-containing (meth)acrylic monomers, as long as the effect of the disinfecting composition of the present invention is not affected. Examples of such monomers include structural units based on styrene-based monomers, vinyl ether monomers, vinyl ester monomers, hydrophilic hydroxyl group-containing (meth)acrylates, acid group-containing monomers, nitrogen-containing group-containing monomers, amino group-containing monomers, and cationic group-containing monomers. Examples of the styrene monomer include styrene, methylstyrene, and chloromethylstyrene. Examples of the vinyl ether monomer include methyl vinyl ether and butyl vinyl ether. Vinyl ester monomers include vinyl acetate and vinyl propionate. Examples of hydrophilic hydroxyl group-containing (meth)acrylates include polyethylene glycol (meth)acrylate, polypropylene glycol (meth)acrylate, N-vinylpyrrolidone, 2-hydroxyethyl (meth)acrylate, 2-hydroxybutyl (meth)acrylate, and 4-hydroxybutyl (meth)acrylate. Examples of the acid group-containing monomer include (meth)acrylic acid, styrenesulfonic acid, and (meth)acryloyloxyphosphonic acid. Nitrogen-containing group-containing monomers include aminoethyl (meth)acrylate. Examples of the amino group-containing monomer include aminoethyl methacrylate, dimethylaminoethyl (meth)acrylate, and N,N-dimethylaminopropyl (meth)acrylamide. An example of the cationic group-containing monomer is 2-hydroxy-3-(meth)acryloyloxypropyltrimethylammonium chloride.

[0020] The weight average molecular weight of the copolymer (P) contained in the disinfecting composition of the present invention is 1,000 to 1,000,000, preferably 5,000 to 500,000, and more preferably 10,000 to 150,000. If the weight-average molecular weight of the copolymer (P) is less than 1,000, the film-forming properties will be reduced and the effect of improving smoothness during use may not be expected, whereas if the weight-average molecular weight is more than 1,000,000, the smoothness of use of the disinfecting composition may be impaired. The weight average molecular weight of the copolymer (P) is measured by gel permeation chromatography (GPC) and is expressed as a pullulan-equivalent molecular weight.

[0021] The polymerization form of the copolymer (P) is not particularly limited, and may be a random copolymer or a block copolymer, with a random copolymer being preferred.

[0022] The copolymer (P) can be produced by a known production method. For example, it can be produced by polymerizing a monomer mixture containing MPC and an alkyl group-containing (meth)acrylic monomer in the presence of a radical polymerization initiator under an inert gas atmosphere such as nitrogen by a known method such as solution polymerization. The content ratio of each monomer may be set to a ratio corresponding to the content ratio of each structural unit in the copolymer (P). The copolymer (P) can be produced by the above-mentioned polymerization method and used, but it is also possible to use a commercially available product as a solution or dispersion in water or a polyhydric alcohol.

[0023] The disinfecting composition of the present invention may contain one selected type of the above copolymer (P) alone, or may contain two or more selected types in combination. The copolymer (P) contained in the disinfecting composition of the present invention may be in any form of a solid such as a powder, or a liquid such as a solution or dispersion.

[0024] The content of the copolymer (P) in the disinfecting composition of the present invention can be appropriately selected from the range of 0.001% by mass to 10% by mass, and from the viewpoint of smooth use, it is preferably selected from the range of 0.005% by mass to 5% by mass. If the content of copolymer (P) in the disinfecting composition of the present invention is less than 0.001% by mass, the disinfecting composition may not be sufficiently smooth to use, whereas if the content of copolymer (P) exceeds 10% by mass, the disinfecting composition may be poorly smooth to use.

[0025] The monohydric alcohol having 1 to 5 carbon atoms contained in the disinfecting composition of the present invention is generally an alcohol having 5 or less carbon atoms, and can be used without any particular limitation as long as it can dissolve the copolymer (P) and fatty acid triglyceride and can be used on the skin. Furthermore, a monohydric alcohol having 3 or less carbon atoms is preferable, and a monohydric alcohol having 2 or 3 carbon atoms is more preferable. Examples of the monohydric alcohol having 1 to 5 carbon atoms that can be preferably used in the present invention include ethanol, 1-propanol, and isopropanol, with ethanol and isopropanol being more preferably used. In the present invention, the monohydric alcohol having 1 to 5 carbon atoms may be used alone or in combination of two or more kinds.

[0026] When the disinfecting composition of the present invention contains a monohydric alcohol having 1 to 5 carbon atoms, the interfacial tension of the disinfecting composition is reduced, and the composition is more likely to spread over uneven areas of the skin, improving the uniformity of the film formation, making it easier to apply the composition evenly to the skin, and improving the smoothness of use. The content of the monohydric alcohol having 1 to 5 carbon atoms in the disinfectant composition of the present invention is 55% by mass to 90% by mass, preferably 60% by mass to 85% by mass, and more preferably 65% ​​by mass to 80% by mass. If the content of the monohydric alcohol having 1 to 5 carbon atoms is less than 55% by mass, the bactericidal power may be inferior. On the other hand, even if the content of the monohydric alcohol having 1 to 5 carbon atoms exceeds 90% by mass, an effect commensurate with the content may not be obtained.

[0027] The fatty acid triglyceride contained in the disinfecting composition of the present invention is preferably liquid at 25° C. and 1013.25 hPa. The fatty acid portion of the fatty acid triglyceride is preferably a straight-chain fatty acid or a branched fatty acid having 6 to 18 carbon atoms, more preferably one having 6 to 10 carbon atoms. Specifically, fatty acid triglycerides in which the fatty acid moiety is selected from caproic acid, caprylic acid, capric acid, isooctanoic acid, isopalmitic acid, isostearic acid, oleic acid, linoleic acid, linolenic acid, etc. are mentioned. Among these, the fatty acid moiety is particularly preferably caproic acid, caprylic acid, capric acid, or isooctanoic acid, and more preferably isooctanoic acid. The fatty acid moiety of the fatty acid triglyceride may be the same fatty acid for all three, or may be a combination of multiple types of fatty acids. Specific examples of such fatty acid triglycerides include, for example, glycerin tricaprylate, glycerin triisooctanoate, glycerin dicaprylate monocaprate, etc., and glycerin triisooctanoate and glycerin tricaprylate are more preferred. In the disinfecting composition of the present invention, the fatty acid triglyceride may be used alone or in combination of two or more kinds.

[0028] The content of fatty acid triglyceride in the disinfecting composition of the present invention is usually 0.001% by mass to 1% by mass, and preferably 0.01% by mass to 1% by mass. If the fatty acid triglyceride content is less than 0.001% by mass, the moist feeling after drying may be poor, and if it exceeds 1% by mass, there is a risk of increased stickiness and sliminess when rubbed into the hands and fingers.

[0029] The disinfecting composition of the present invention may contain a bactericide, if necessary, from the viewpoint of disinfecting effect. In the disinfecting composition of the present invention, the bactericide is an agent capable of killing or inhibiting the growth of pathogenic microorganisms, can be used for disinfecting the skin, and can be used without any particular limitation as long as it does not inhibit the effects of the copolymer (P) and the fatty acid triglyceride. Examples of such surfactants include cationic surfactants such as benzalkonium chloride, benzethonium chloride, and cetylpyridinium chloride; amphoteric surfactants such as alkyldiaminoethylglycine hydrochloride; biguanide compounds such as chlorhexidine gluconate and chlorhexidine hydrochloride; halogen (iodine) compounds such as iodine ion, iodoform, and povidone iodine; silver-based inorganic compounds such as silver ion; and phenolic compounds such as cresol and isopropylmethylphenol. From the viewpoints of bactericidal activity and low irritation to the skin, benzalkonium chloride, benzethonium chloride, chlorhexidine gluconate, etc. are preferably used. In the disinfecting composition of the present invention, one type of bactericide may be used alone, or two or more types may be selected and used in combination. The content of the bactericide in the disinfecting composition of the present invention can be appropriately set depending on the type of bactericide, etc., but is preferably 0.01% by mass to 5% by mass, more preferably 0.01% by mass to 0.05% by mass.

[0030] The disinfecting composition of the present invention may contain an organic acid, if necessary, from the viewpoint of improving the feeling upon use. In the disinfecting composition of the present invention, the organic acid is an agent that improves moist feeling and can be used without particular limitation as long as it does not inhibit the effects of the MPC copolymer and the fatty acid triglyceride, and examples of the organic acid include citric acid, malic acid, and lactic acid. From the viewpoints of moist feeling and low irritation to the skin, lactic acid and the like are preferably used. In the disinfecting composition of the present invention, one type of organic acid may be used alone, or two or more types may be selected and used in combination. The content of the organic acid in the disinfecting composition of the present invention can be appropriately set depending on the type of organic acid, etc., but is usually 0.01% by mass to 10% by mass, and preferably 1% by mass to 10% by mass.

[0031] The disinfecting compositions of the present invention typically contain water as a base. In preparing the disinfectant composition of the present invention, the above-mentioned monohydric alcohol having 1 to 5 carbon atoms is used as a mixed solvent with water, thereby improving the adhesion of the MPC copolymer and fatty acid triglyceride to the skin. The reason for the improved adhesion is that when the composition is dried, the evaporation rates of the monohydric alcohol having 1 to 5 carbon atoms and water are different, so that the hydrophobic groups of the MPC copolymer and fatty acid triglyceride can be effectively oriented on the skin surface. The water contained in the disinfecting composition of the present invention may be water generally used for cosmetics or pharmaceuticals, and it is preferable to use ion-exchanged water, purified water, water for injection, etc. The water content of the disinfecting composition of the present invention is 10% by mass to 35% by mass, and preferably 15% by mass to 30% by mass. If the water content is less than 3% by mass or more than 45% by mass, the disinfecting power may be inferior, which is not preferable.

[0032] The disinfecting composition of the present invention may contain a wetting agent to the extent that the effect of the present invention is not impaired. Examples of humectants include dihydric alcohols such as ethylene glycol, propylene glycol, dipropylene glycol, 1,3-butylene glycol, 1,4-butylene glycol, pentylene glycol, hexylene glycol, isoprene glycol, 2-ethyl-1,3-hexanediol, and isopentyldiol; glycerin; glycerin condensates such as diglycerin and polyglycerin; and sugar alcohols such as sorbitol, xylitol, maltitol, mannitol, and erythritol, and other polyol-based compounds. These may be used alone or in combination of two or more. Among these moisturizing agents, propylene glycol, dipropylene glycol, 1,3-butylene glycol and glycerin are more preferably used because of their good compatibility with the skin. The content of the wetting agent in the disinfecting composition of the present invention is selected within a range that does not impair the effects of the present invention, and is preferably 0.01% by mass to 10% by mass.

[0033] The disinfecting composition of the present invention may further contain additives that are generally used in external preparations such as known disinfecting compositions, within the scope of not impairing the effects of the present invention. Examples of the additives include nonionic surfactants, thickeners, foaming agents, propellants, organic acids, antioxidants, stabilizers, preservatives, sequestering agents, fragrances, dyes, coloring materials, etc. One or more of these additives can be selected and contained depending on the purpose.

[0034] The disinfecting composition of the present invention can be produced according to a conventional method. For example, it can be produced by adding a bactericide, water, a wetting agent, or other general additives to the above-mentioned MPC copolymer, a monohydric alcohol having 1 to 5 carbon atoms, a fatty acid triglyceride, etc., as necessary, and appropriately mixing and homogenizing the mixture. Furthermore, the disinfecting composition of the present invention can be used, for example, as a medicine or quasi-drug, or as a component thereof.

[0035] The disinfecting composition of the present invention can be provided in the form of a liquid, a semi-solid such as a paste, or the like. From the viewpoints of ease of use, safety, and the like, the disinfecting composition of the present invention is preferably in a liquid form. The disinfecting composition of the present invention can be contained in a pump container or a spray container. In detail, it is preferable to use the disinfecting composition in a liquid discharge type filled in a container with a dispenser pump, a spray type filled in a container with a spray pump, a foam discharge type filled in a container with a foamer pump or an aerosol container, or an impregnated type impregnated in a cleaning wipe. As an example of how the disinfectant composition of the present invention can be used to disinfect hands and fingers, an appropriate amount (about 1 mL to 3 mL) of the disinfectant composition of the present invention can be taken, rubbed into the hands, and then dried before use. When the disinfecting composition of the present invention is impregnated into a wiping wipe, about 10 to 400 parts by mass of the disinfecting composition of the present invention is impregnated into 100 parts by mass of the wiping wipe, and the wipe can be used to wipe the skin or medical instruments.

[0036] The disinfecting composition of the present invention provides a moist feeling without stickiness on the skin after application, and further provides a smooth feeling when using an electronic device immediately after application. Specifically, when a user uses the disinfecting composition of the present invention on the hands, fingers, etc., the user not only feels a pleasant sensation of non-stickiness on the skin and a moist feeling upon use, but also can prevent rough hands and the like due to the fatty acid triglyceride contained in the composition, and further, when using an electronic device (e.g., a keyboard, a tablet terminal, a smartphone, a medical device) immediately after application, the electronic device can be used smoothly. EXAMPLES

[0037] The disinfecting composition of the present invention will be specifically described below with reference to examples and comparative examples, but the present invention is not limited thereto. In addition, various evaluations and tests of the disinfecting composition of the present invention were carried out as follows.

[0038] [Examples 1 to 10 and Comparative Examples 1 to 6] According to the formulations shown in Table 1 below, the disinfecting compositions of Examples 1 to 10 and Comparative Examples 1 to 6 were prepared as follows. MPC copolymer (1): MPC-butyl methacrylate copolymer (copolymerization ratio of MPC and butyl methacrylate [MPC / butyl methacrylate] (molar ratio) = 30 / 70, weight average molecular weight = 100,000) MPC copolymer (2): MPC-butyl methacrylate copolymer (copolymerization ratio of MPC and butyl methacrylate [MPC / butyl methacrylate] (molar ratio) = 80 / 20, weight average molecular weight = 600,000) Glyceryl triisooctanoate: "Panasate 800B" manufactured by NOF Corporation Glyceryl tricaprylate: "Panasate 810S" manufactured by NOF Corporation Glycerin: concentrated glycerin ("Japanese Pharmacopoeia concentrated glycerin-S", manufactured by NOF Corporation) Benzalkonium chloride: "Nissan Cation M2-100" manufactured by NOF Corporation Ethanol, lactic acid, water: Commercially available topical products Ethanol was added to 10 g of purified water, fatty acid triglyceride was added, and then MPC copolymer was added, and other components were added as necessary, and the mixture was stirred and mixed to be homogenous. Purified water was added so that the total amount became 100 g, and each disinfectant composition of Examples 1 to 10 and Comparative Examples 1 to 6 was prepared.

[0039] (GPC measurement) The GPC measurement of the above MPC copolymer was carried out under the following conditions. GPC system: EcoSEC system (manufactured by Tosoh Corporation) Column: Shodex OHpak SB-802.5HQ (Showa Denko K.K.) and SB-806HQ (Showa Denko K.K.) connected in series Developing solvent: 20 mM sodium phosphate buffer (pH 7.4) Detector: Differential refractive index detector Molecular weight standard: EasiVial PEG / PEO (Agilent Technologies) Flow rate: 0.5mL / min Column temperature: 40℃ Sample: Dilute each obtained MPC copolymer with the developing solvent to a final concentration of 0.1% by weight. Injection volume: 100μL

[0040] For each of the disinfecting compositions of the above Examples and Comparative Examples, the stickiness of the skin after application, the moistness of the skin after application, and the smoothness of use when using a keyboard immediately after application to the skin were evaluated as follows.

[0041] (1) Evaluation of stickiness on the skin after application ("stickiness after drying") The sticky feeling on the skin after application of each of the disinfecting compositions of the Examples and Comparative Examples was evaluated by a sensory evaluation conducted by 30 male and female panelists aged 25 to 57 years. Under an environment of room temperature = 25 ° C. and relative humidity = 60%, each panelist took 3 mL of each disinfectant composition on their hand and rubbed it into their fingers 10 times, and then evaluated the sticky feeling of the fingers according to the following evaluation criteria. The total score of the evaluation points of the 30 panelists was calculated, and the sticky feeling was evaluated according to the following judgment criteria. <Evaluation criteria> No sticky feeling: 3 points Slightly non-sticky: 2 points Slightly sticky: 1 point Sticky feeling: 0 points <Judgment criteria> 61 points to 90 points: ++; A disinfectant composition that does not leave a sticky feeling on the skin after application. 31 points to 60 points: +; A disinfectant composition that does not leave a sticky feeling on the skin after application. 30 points or less: ×; The disinfectant composition leaves the skin sticky after application.

[0042] (2) Evaluation of moist feeling on skin after application ("moist feeling after drying") The moist feeling of the skin after application of each of the disinfecting compositions of the Examples and Comparative Examples was evaluated by a sensory evaluation conducted by 30 male and female panelists aged 25 to 57 years. Under an environment of room temperature = 25 ° C. and relative humidity = 60%, each panelist took 3 mL of each disinfectant composition and rubbed it into their fingers 10 times, and then evaluated the moist feeling of the fingers according to the following evaluation criteria. The total score of the evaluation points of the 30 panelists was calculated, and the moist feeling was judged according to the following judgment criteria. <Evaluation criteria> Moist: 3 points Slightly moist: 2 points Slightly moist: 1 point No moist feeling: 0 points <Judgment criteria> 61 points to 90 points: ++; A disinfectant composition that leaves the skin feeling sufficiently moisturized after application. 31 to 60 points: +; A disinfectant composition that leaves the skin feeling moisturized after application. 30 points or less: ×; The disinfectant composition does not leave the skin feeling moisturized after application.

[0043] (3) Evaluation of ease of use when using a keyboard after application to the skin ("ease of use") The ease of use of each disinfecting composition of the Examples and Comparative Examples was evaluated by a sensory evaluation conducted by 30 male and female panelists aged 25 to 57 years. In an environment of room temperature = 25 ° C. and relative humidity = 60%, each panelist took 3 mL of each disinfectant composition and rubbed it into their fingers 10 times, and then immediately used a keyboard ("TK-FCM064WH / RS" manufactured by ELECOM Co., Ltd.) and evaluated the ease of use according to the following evaluation criteria. The total score of the evaluation points of the 30 panelists was calculated, and the ease of use was evaluated according to the following evaluation criteria. <Evaluation criteria> Able to use keyboard smoothly; 3 points The keyboard can be used somewhat smoothly; 2 points Difficulty using the keyboard smoothly; 1 point Cannot use the keyboard smoothly; 0 points <Judgment criteria> 61 points to 90 points: ++; A disinfectant composition that is easy to use. 31 points to 60 points: +; A disinfectant composition that is somewhat easy to use. 30 points or less: ×; The disinfectant composition is not easy to use.

[0044] The evaluation results for the sticky feeling on the skin after application, the moist feeling on the skin after application, and the smoothness of use are also shown in Table 1.

[0045] [Table 1]

[0046] As shown in Table 1, for each of the disinfecting compositions of Examples 1 to 10 of the present invention, the skin after application was rated as having little or no stickiness, having a moist feeling or being sufficiently moist, and being slightly excellent or excellent in smoothness of use. The disinfecting compositions of Examples 2, 3, 4, 6, 7, 8, 9 and 10, which contained 0.5% by mass or more of fatty acid triglyceride, were evaluated as providing a sufficient moist feeling to the skin after application. The disinfectant compositions of Examples 4, 8 and 9, which contained lactic acid, were evaluated as having excellent moisturizing feel. The disinfecting compositions of Comparative Examples 1 and 2, which do not contain fatty acid triglycerides, were evaluated as lacking in smoothness of use. The disinfecting composition of Comparative Example 3, which does not contain an MPC copolymer, was evaluated as lacking in smoothness of use. The disinfecting composition of Comparative Example 4 contained glycerin instead of fatty acid triglyceride, and was therefore evaluated as having a sticky feeling on the skin after application and lacking smoothness in use. It was confirmed that the disinfecting composition of Comparative Example 5 was not suitable for evaluation because the ratio of the contents of structural units (1) and (2) in the MPC copolymer was not appropriate, and therefore did not become a colorless, clear liquid. The disinfecting composition of Comparative Example 6 had a high content of glycerin triisooctanoate, and was therefore evaluated as having a sticky feeling on the skin after application and lacking smoothness in use.

[0047] From the above evaluation results of each disinfectant composition of the Examples and Comparative Examples, the disinfectant composition of the present invention can provide a moist feeling of use without stickiness on the skin after application, compared to the disinfectant composition of the Comparative Examples, and can also provide smooth use of electronic devices. [Industrial Applicability]

[0048] According to the present invention, a disinfecting composition can be provided that can provide a moist feeling of use without stickiness on the skin after application, and can also facilitate the smooth use of electronic devices.

Claims

1. (1) 0.001% by mass to 10% by mass of a copolymer (P) having a weight average molecular weight of 1,000 to 1,000,000, comprising a structural unit (1) based on 2-(meth)acryloyloxyethyl phosphorylcholine represented by the following formula (1) and a structural unit (2) based on an alkyl group-containing (meth)acrylic monomer represented by the following formula (2), the content ratio of the structural unit (1) to the structural unit (2) being 15:85 to 45:55 in molar ratio; (2) 55% to 90% by mass of a monohydric alcohol having 1 to 5 carbon atoms; and (3) Fatty acid triglyceride: 0.001% by mass to 1% by mass 1. A disinfecting composition comprising: 【Chemistry 1】 (In formula (1), R 1 represents a hydrogen atom or a methyl group.) 【Chemistry 2】 (In formula (2), R 2 represents a hydrogen atom or a methyl group, R 3 represents an alkyl group having 4 to 22 carbon atoms.

2. The disinfecting composition according to claim 1, wherein the monohydric alcohol having 1 to 5 carbon atoms is one or more selected from the group consisting of ethanol and isopropanol.

3. The disinfecting composition according to any one of claims 1 to 2, wherein the fatty acid triglyceride is one or more selected from the group consisting of glycerin triisooctanoate and glycerin tricaprylate.

4. The disinfecting composition according to any one of claims 1 to 3, further comprising an organic acid.

Citation Information

Patent Citations

  • Sterilizer / disinfectant for external use

    JP2004155712A

  • Quick-drying transparent lotion for sterilization

    JP2008115125A

  • Gel-like bactericide for finger

    JP2011144146A

  • Hand disinfectant composition

    JP2011219410A