Method for preparing alcohol degradation accelerator

Abstract

The present invention relates to a method for preparing an alcohol degradation accelerator, comprising the steps of: (a) extracting gluten meal from corn; (b) extracting natural additives from spinach, bean sprouts and soybeans; (c) mixing the gluten meal with an alkaline protease so as to prepare a first gluten meal reaction solution in which alkaline proteins are degraded; (d) mixing the first gluten meal reaction solution with a neutral protease so as to prepare a second gluten meal reaction solution in which neutral proteins are degraded; (e) obtaining oligopeptides in a powder form from the second gluten meal reaction solution; and (f) mixing the oligopeptides and the natural additives so as to prepare an alcohol degradation accelerator.

Description

Method for manufacturing an alcohol decomposition accelerator

[0001] The present invention relates to a method for producing an alcohol decomposition promoter, and more particularly, to a method for producing an alcohol decomposition promoter that can protect the liver from damage caused by excessive drinking or chronic alcohol consumption by stably reducing blood alcohol concentration by promoting alcohol metabolism.

[0002] In general, alcoholic liver disease (ALD) caused by habitual drinking is increasing significantly along with increasing alcohol consumption. Based on clinical and pathological findings, ALD can be broadly categorized into fatty liver, alcoholic hepatitis, and alcoholic cirrhosis.

[0003] Here, alcohol is mainly absorbed in the digestive organs, and about 10% of the alcohol absorbed into the body is excreted through the lungs, urine, and sweat, and 90% is metabolized in the liver.

[0004] Additionally, alcohol that moves to the liver through the blood is oxidized into acetaldehyde by several enzymes produced in the liver (Alcohol Dehydrogenase, Microsomal ethanol oxidizing system, Catalase, etc.), and acetaldehyde is then oxidized by enzymes into acetic acid, which is harmless to the body.

[0005] Meanwhile, alcohol is easily oxidized to acetaldehyde by numerous microorganisms present in the intestines. Acetaldehyde, a metabolite produced by alcohol oxidation, is a highly reactive toxic substance that binds to proteins, inhibiting enzyme activity. It can damage mitochondria by increasing lipid oxidation and lipid peroxidation. It can also lead to glutathione deficiency, as well as deficiencies in pyridoxine, vitamin A, zinc, and selenium. It also inhibits tubulin polymerization, inhibiting protein secretion and transport. Acetaldehyde is a major factor in liver damage.

[0006] Additionally, free radical production by acetaldehyde promotes collagen synthesis in the liver, which is reported to be a cause of liver fibrosis (cirrhosis) in chronic alcoholics.

[0007] To this end, many products such as alcohol metabolism inhibitors, alcohol metabolism accelerators, and alcohol decomposition enzymes are being developed, and research is actively being conducted on drugs that can alleviate the burden on the liver by reducing its burden.

[0008]

[0009] In order to solve such problems, the present invention has been conceived based on the aforementioned background technology, and its purpose is to provide a method for manufacturing an alcohol decomposition promoter that can protect the liver from damage caused by excessive drinking or chronic alcohol consumption by stably reducing blood alcohol concentration by promoting alcohol metabolism.

[0010] In addition, the present invention aims to provide a method for manufacturing an alcohol decomposition promoter that can be provided inexpensively and is easy to mass-produce by manufacturing an alcohol decomposition promoter using inexpensive gluten wheat as the main ingredient.

[0011] According to one embodiment of the present invention for achieving such a task, the method comprises the steps of: (a) extracting gluten meal from corn; (b) extracting natural additives from spinach, bean sprouts, and soybeans; (c) mixing an alkaline protein-decomposing enzyme into the gluten meal to prepare a first gluten meal reaction solution in which alkaline proteins are decomposed; (d) mixing a neutral protein-decomposing enzyme into the first gluten meal reaction solution to prepare a second gluten meal reaction solution in which neutral proteins are decomposed; (e) obtaining a powdered oligopeptide from the second gluten meal reaction solution; and (f) mixing the oligopeptide and the natural additive to prepare an alcohol decomposition promoter.

[0012] According to one embodiment of the present invention, the step (a) comprises: (a1) drying corn at a temperature of 105°C to 125°C to remove moisture, and grinding the corn into a powder having particles of 400 μm or less; (a2) diluting 5 to 15 parts by weight of corn powder with respect to 100 parts by weight of water, allowing it to settle for 20 to 40 minutes, and obtaining gluten meal formed on the upper layer of the sediment; (a3) ​​preparing a gluten meal mixture by mixing 10 to 15 parts by weight of gluten meal with respect to 100 parts by weight of water; (a4) adding hydroxide to the gluten meal mixture to adjust the pH of the gluten meal mixture to 9 to 10, and extracting solid gluten meal from the gluten meal mixture with the pH adjusted; (a5) A step of purifying and filtering solid gluten wheat by adding 100 L of washing water (water) per 10 kg to 12 kg of gluten wheat to a stirrer and stirring at a temperature of 50°C to 80°C for 60 to 90 minutes; (a6) A step of concentrating the purified and filtered gluten wheat and drying the concentrated gluten wheat; and (a7) A step of selecting high-purity gluten wheat containing a protein content of 85 wt% or more.

[0013] According to one embodiment of the present invention, the step (b) is characterized by including: (b1) a step of removing moisture contained in spinach, bean sprouts, and soybeans, and pulverizing the spinach, bean sprouts, and soybeans from which moisture has been removed; (b2) a step of extracting vitamin B6 from the pulverized spinach powder; and (b3) a step of extracting vitamin B1, vitamin B2, and amino acids from the bean sprouts and soybean powder, respectively.

[0014] According to one embodiment of the present invention, the step (c) is characterized by including: (c1) a step of preparing a gluten wheat mixture by adding 8 to 12 parts by weight of an alkaline protein decomposing enzyme to 100 parts by weight of gluten wheat; (c2) a step of setting the pH to 7 to 9 by adding a hydroxide brine solution to the gluten wheat mixture; and (c3) a step of heating the mixture at pH 7 to 9 to 45 to 60°C while stirring and reacting for 3 to 10 hours to prepare a first gluten wheat reaction solution.

[0015] According to one embodiment of the present invention, the alkaline protein decomposing enzyme is characterized by being one or a mixture of two or more of papain, aloe vera extract, bromelain, and panthenone.

[0016] According to one embodiment of the present invention, the step (d) is characterized by including: (d1) a step of adjusting the pH of the first gluten meal reaction solution to 5 to 5.5 by adding 4 to 20 parts by weight of water to 100 parts by weight of the first gluten meal reaction solution; (d2) a step of adding 0.5 to 5 parts by weight of a neutral protein-decomposing enzyme to 100 parts by weight of the first gluten meal reaction solution, the pH of which has been adjusted; (d3) a step of adjusting the pH of the first gluten meal reaction solution to 6 to 8 by adding hydrochloric acid to the neutral protein-decomposing enzyme; and (d4) a step of reacting the first gluten meal reaction solution to which the neutral protein-decomposing enzyme has been added while heating and stirring at 35 to 55°C for 3 to 10 hours to prepare a second gluten meal reaction solution.

[0017] According to one embodiment of the present invention, the neutral protein decomposing enzyme is characterized by being any one of Lactobacillus acidophilus and Saccharomyces cerevisiae.

[0018] According to one embodiment of the present invention, the step (e) is characterized by including: (e1) a step of mixing an extraction solvent into a second gluten meal reaction solution, heating and stirring at a temperature of 40°C to 60°C for 20 to 24 hours, and then centrifuging to separate a solid phase and a liquid phase; (e2) a step of filtering the separated liquid phase, and adjusting the pH of the filtered filtrate to 7 to 9; (e3) a step of purifying the filtrate after adjusting the pH; (e4) a step of concentrating the purified filtrate to obtain an oligopeptide; and (e5) a step of drying the obtained oligopeptide to prepare it in a powder form.

[0019] According to one embodiment of the present invention, the powder-form oligopeptide is characterized by having a crude protein content of 85 wt% or more and a low molecular weight of 1,000 Da or less.

[0020] According to one embodiment of the present invention, the step (f) is characterized in that an alcohol decomposition accelerator is manufactured by mixing 25 to 40 parts by weight of amino acids and 0.1 to 0.9 parts by weight of a vitamin B complex including vitamin B1, vitamin B2, and vitamin B6 per 100 parts by weight of oligopeptide.

[0021] According to one embodiment of the present invention, the vitamin B complex is characterized in that vitamin B1, vitamin B2, and vitamin B6 are each composed of a weight ratio of 1:1:3.

[0022] According to an embodiment of the present invention, there is an effect of promoting alcohol metabolism to stably reduce blood alcohol concentration, thereby protecting the liver from damage caused by excessive drinking or chronic alcohol consumption.

[0023] According to an embodiment of the present invention, by manufacturing an alcohol decomposition accelerator using inexpensive gluten wheat as the main ingredient, it is possible to provide it inexpensively and is easy to mass-produce.

[0024] Figures 1 and 2 are flowcharts schematically showing a manufacturing process of an alcohol decomposition accelerator according to one embodiment of the present invention.

[0025]

[0026] Hereinafter, embodiments of the present invention will be described in detail with reference to the attached drawings.

[0027] As illustrated, the alcohol decomposition accelerator of the present invention performs a main ingredient extraction step (S110) of pulverizing main raw materials including corn, spinach, bean sprouts, and soybeans, and extracting main ingredients that provide alcohol decomposition efficacy from the main raw materials in powder form.

[0028] The main component extraction step (S110) first performs a step of extracting gluten wheat from corn.

[0029] The gluten wheat extraction step (S210) is a step of drying corn to remove moisture, grinding the corn from which moisture has been removed to obtain corn pulverized material, and filtering and refining the obtained corn pulverized material to obtain gluten wheat.

[0030] The gluten wheat extraction step (S210) is a step of drying harvested corn at a temperature of 105℃ to 125℃ to remove moisture contained in the corn, and grinding the corn from which moisture has been removed into a powder having particles of 400㎛ or less.

[0031] At this time, the gluten wheat extraction step (S210) can be performed through a conventional drying method such as shelf drying, hot air drying, fluidized bed drying, etc. when removing moisture from corn.

[0032] In addition, the gluten wheat extraction step (S210) may be performed by performing a step of degreasing and destarching corn flour to separate gluten wheat from impurities or unnecessary fat and starch contained in the corn flour, and then purifying and filtering the separated gluten wheat to separate gluten wheat contained in the corn flour, thereby obtaining gluten wheat.

[0033] At this time, the gluten wheat extraction step (S210) may be obtained by mixing and diluting 5 to 15 parts by weight of corn powder with 100 parts by weight of water when separating gluten wheat through a de-oiling and de-starch process, and then allowing it to settle for 20 to 40 minutes, and then separating the gluten wheat in a solid state formed in the upper layer of the sediment.

[0034] Additionally, a further step of drying the separated gluten meal may be performed.

[0035] In addition, the gluten wheat extraction step (S210) performs a step of purifying and filtering the separated gluten wheat to obtain high-purity purified gluten wheat containing a protein content of 85 wt% or more.

[0036] At this time, the gluten wheat extraction step (S210) prepares a gluten wheat mixture by mixing 10 to 15 parts by weight of gluten wheat to 100 parts by weight of water during the purification of gluten wheat, and adjusts the pH of the gluten wheat mixture by adding a certain weight part of hydroxide to the prepared gluten wheat mixture.

[0037] In the present invention, among the hydroxides, it may be an alkali metal hydroxide, preferably one selected from the group consisting of sodium hydroxide and potassium hydroxide, and more preferably one of sodium hydroxide or potassium hydroxide.

[0038] At this time, in the present invention, 1 to 1.5 parts by weight of alkali metal hydroxide is added to 100 parts by weight of a gluten wheat mixture to adjust the pH of the gluten wheat mixture to 9 to 10, and the pH-adjusted gluten wheat mixture is heated to 50°C to 80°C and stirred for 60 to 90 minutes, and then the gluten wheat solid is separated and extracted by centrifugation.

[0039] Afterwards, 100 L of washing water (water) per 10 kg to 12 kg of gluten wheat is added to the stirrer, stirred at a temperature of 50°C to 80°C for 60 to 90 minutes to purify and filter the solid gluten wheat to remove impurities contained in the solid gluten wheat, and then the solid gluten wheat and washing water are separated by centrifugation to obtain purified gluten wheat.

[0040] Additionally, the gluten wheat extraction step (S210) may include a step of concentrating the refined gluten wheat using a vacuum evaporator or a rotary evaporator to reduce the moisture content of the refined gluten wheat.

[0041] At this time, the concentration of the refined gluten wheat can be performed under low pressure conditions, and it is preferable to maintain the temperature of the gluten wheat while concentrating in order to maintain the quality of the gluten wheat, i.e., the protein content of the gluten wheat.

[0042] Additionally, the gluten wheat extraction step (S210) performs a step of drying the concentrated gluten wheat under high temperature and low pressure conditions.

[0043] Meanwhile, the gluten wheat extraction step (S210) may be a step of selecting high-purity gluten wheat containing 85 wt% or more of the protein of the present invention.

[0044]

[0045] Next, the main ingredient extraction step (S110) performs a natural additive ingredient extraction step (S120) corresponding to a natural additive that extracts vitamin B complex, such as vitamin B1 (thiamine), vitamin B2 (riboflavin), and vitamin B6 (pyridoxine), and amino acids to be included in the alcohol decomposition promoter from spinach, bean sprouts, and soybeans among the main raw materials.

[0046] The natural additive ingredient extraction step (S120) is a step of removing moisture from spinach, bean sprouts, and soybeans, and grinding the spinach, bean sprouts, and soybeans from which moisture has been removed to produce ground spinach, and ground bean sprouts and soybeans.

[0047] At this time, the removal of moisture from spinach, bean sprouts, and soybeans can be performed in the same manner as the drying method of corn described above, and among the spinach, bean sprouts, and soybeans from which moisture has been removed, spinach can be ground to a size of 200 μm to 400 μm, and bean sprouts and soybeans can be ground to a size of 100 μm or less.

[0048] The natural additive extraction step (S120) performs a step of extracting vitamin B6 (pyridoxine) from crushed spinach powder.

[0049] At this time, the natural additive ingredient extraction step (S120) can be performed by adding spinach powder to an extraction solvent, and in the present invention, spinach powder can be added to the extraction solvent at a weight ratio of 1:10.

[0050] Here, the extraction solvent may be any one of ethanol, methanol, and acetone, and preferably 70% ethanol.

[0051] Afterwards, the spinach powder is added to the extraction solvent and soaked at 50°C to 70°C for 20 to 24 hours, stirred for 40 to 60 minutes, and then a paratoxin extract is obtained by centrifugation.

[0052] Thereafter, the obtained paratoxin extract is filtered to remove spinach tissue and other insoluble substances, and the filtered paratoxin extract is concentrated by a reduced pressure concentration method to improve the purity of paratoxin contained in the paratoxin extract.

[0053] Afterwards, the concentrated paratoxin extract can be dried to obtain paratoxin in powder form.

[0054] In addition, the natural additive ingredient extraction step (S120) performs a step of extracting vitamin B1 (thiamine), vitamin B2 (riboflavin), and amino acids from soybean sprouts and soybean powder, respectively.

[0055] At this time, the natural additive component extraction step (S120) can be performed by mixing and extracting bean sprouts and soybean powder by adding them to the aforementioned extraction solvent, and in the present invention, bean sprouts and soybean powder can be added to the extraction solvent at a weight ratio of 1:5 to 8 and mixed.

[0056] Afterwards, the extraction solvent containing the soybean sprouts and soybean powder is heated at 40°C to 50°C for 60 to 90 minutes to obtain an extract containing vitamins B1 and B2, and the obtained extract is filtered to remove impurities contained in the extract, and then vitamins B1 and B2 can be obtained through a conventional purification, concentration, and drying process.

[0057] In addition, the natural additive extraction step (S120) may be performed by introducing amino acids from soybean sprouts and soybean powder into an extraction solvent consisting of a water-soluble solvent at a weight ratio of 1:8 to 10, soaking for 24 hours, and then extracting the extract using a centrifugal separation method.

[0058] Here, the water-soluble solvent can be any one of water, alcohol, and isopropanol.

[0059] Afterwards, the extract is filtered to separate the amino acid in solid form, and an amino acid extract can be obtained through a process of conventional amino acid purification, concentration, and drying.

[0060]

[0061] In the present invention, after the main component extraction step (S110), a first gluten wheat reaction solution preparation step (S120) is performed to prepare a first gluten wheat reaction solution in which alkaline protein is decomposed by mixing an alkaline protein-decomposing enzyme into gluten wheat.

[0062] In the first gluten wheat reaction solution manufacturing step (S120), a gluten wheat mixture is manufactured by adding 8 to 12 parts by weight of an alkaline protein decomposing enzyme to 100 parts by weight of gluten wheat (converted to dry weight), and then a hydroxide brine solution is added to the gluten wheat mixture to set the pH of the gluten wheat mixture to 7 to 9.

[0063] At this time, the hydroxide brine solution may be a sodium hydroxide solution, but is not limited thereto.

[0064] Thereafter, in the first gluten wheat reaction solution manufacturing step (S120), a gluten wheat mixture having a pH of 7 to 9 is heated to 45 to 60°C while stirring and reacted for 3 to 10 hours to manufacture a first gluten wheat reaction solution.

[0065] Meanwhile, the alkaline protein decomposing enzyme used in the present invention may be one of papain, aloe vera extract, bromelain, and panthenone, or a mixture of two or more thereof.

[0066] Here, papain is an enzyme found in the fruit of pineapple, which acts to break down proteins.

[0067] Additionally, aloe vera extract is an ingredient extracted from the aloe vera plant that helps promote digestion and support gastrointestinal health, as well as reducing inflammation and soothing the digestive system.

[0068] Additionally, bromelain is an enzyme extracted from pineapple that is used to break down proteins, helping to improve digestion and alleviate digestive problems.

[0069] Additionally, panthenone, a form of vitamin B5, enhances the activation of enzymes required for fat, carbohydrate, and protein metabolism.

[0070]

[0071] In the present invention, after the first gluten wheat reaction solution preparation step (S120), a second gluten wheat reaction solution preparation step (S130) is performed to prepare a second gluten wheat reaction solution in which neutral proteins are decomposed by adding a neutral protein-decomposing enzyme to the first gluten wheat reaction solution.

[0072] The second gluten wheat reaction solution manufacturing step (S130) adjusts the concentration of the first gluten wheat reaction solution by adding a certain amount of water to the first gluten wheat reaction solution.

[0073] At this time, the second gluten wheat reaction solution manufacturing step (S130) of the present invention is to adjust the pH of the first gluten wheat reaction solution to 5 to 5.5 by adding 4 to 20 parts by weight of water to 100 parts by weight of the first gluten wheat reaction solution, thereby having a concentration that enables optimal functional activation of the neutral protein decomposition enzyme.

[0074] Thereafter, in the second gluten wheat reaction solution manufacturing step (S130), a neutral protein-decomposing enzyme is added to the first gluten wheat reaction solution, the pH of which has been adjusted, to decompose neutral proteins.

[0075] At this time, in the second gluten wheat reaction solution manufacturing step (S130), 0.5 to 5 parts by weight of neutral protein decomposition enzyme can be added to 100 parts by weight of the first gluten wheat reaction solution.

[0076] Thereafter, in the second gluten wheat reaction solution manufacturing step (S130), the pH of the first gluten wheat reaction solution to which neutral protein decomposition enzyme has been added is adjusted to 6 to 8, and when the pH adjustment is complete, the first gluten wheat reaction solution to which neutral protein decomposition enzyme has been added is reacted for 3 to 10 hours while heating and stirring at 35°C to 55°C to manufacture a second gluten wheat reaction solution in which neutral protein has been decomposed.

[0077] At this time, adjustment can be made by adding hydrochloric acid to the first gluten wheat reaction solution to which neutral protein decomposition enzyme has been added, but is not limited thereto.

[0078] Additionally, the neutral protein decomposing enzyme in the present invention may be a digestive enzyme based on a microbial fermentation extract, and in the present invention, may be Lactobacillus acidophilus or Saccharomyces cerevisiae.

[0079] Lactobacillus acidophilus is a type of lactic acid bacteria that acts as a probiotic and has a positive effect on digestive health. It produces digestive enzymes such as proteases to help digest proteins.

[0080] Additionally, Saccharomyces cerevisiae is a type of yeast that is primarily used in the fermentation process, producing digestive enzymes such as alcohol and lactase, which improve carbohydrate and protein digestion.

[0081]

[0082] In the present invention, after the second gluten wheat reaction solution preparation step (S130), an oligopeptide obtaining step (S140) is performed to obtain an oligopeptide from the second gluten wheat reaction solution.

[0083] The oligopeptide obtaining step (S140) is performed by mixing an extraction solvent made of water or alcohol into the second gluten meal reaction solution, heating and stirring at a temperature of 40°C to 60°C for 20 to 24 hours to remove neutral proteins and alkaline proteins present in trace amounts in the second gluten meal reaction solution, and then centrifuging to separate the solid phase and the liquid phase.

[0084] Afterwards, in the oligopeptide obtaining step (S140), the separated liquid is filtered using a ceramic filter and a nanofilter, and the pH of the filtered filtrate is adjusted to 7 to 9.

[0085] At this time, the separated moisture can be filtered through a ceramic filter to remove remaining neutral proteins and alkaline proteins, and can also be passed through a nanofilter to remove remaining low-molecular salts or amino acids.

[0086] Additionally, sodium hydroxide can be used to adjust the pH of the filtrate, but is not limited thereto.

[0087] Thereafter, in the oligopeptide obtaining step (S140), the filtrate, the pH of which has been adjusted, is purified, concentrated, and dried using the purification, concentration, and drying methods described above to obtain an oligopeptide in powder form.

[0088] The oligopeptide in the present invention may have a crude protein content of 85% by weight or more and a low molecular weight of 1,000 Da or less, which is easily absorbed efficiently into the blood through the intestines.

[0089]

[0090] The present invention performs an alcohol decomposition promoter manufacturing step (S150) of manufacturing an alcohol decomposition promoter by mixing the obtained gluten meal and natural additives at a certain weight ratio after the oligopeptide obtaining step (S140).

[0091] The alcohol decomposition accelerator manufacturing step (S150) may be mixed with 25 to 40 parts by weight of amino acids and 0.1 to 0.9 parts by weight of vitamin B complex including vitamin B1, vitamin B2, and vitamin B6 per 100 parts by weight of oligopeptide.

[0092] At this time, the vitamin B complex may be composed of vitamin B1, vitamin B2, and vitamin B6 in a weight ratio of 1:1:3, but is not limited thereto.

[0093] Meanwhile, the formulation of the alcohol decomposition accelerator manufactured through the alcohol decomposition accelerator manufacturing step (S150) is not particularly limited, and may be provided in a formulation form such as a powder form, capsule form, pill form, or solution form that is easy to take orally.

[0094] The above description is merely an illustrative illustration of the technical idea of ​​the present invention, and those skilled in the art will appreciate that various modifications and variations can be made without departing from the essential characteristics of the present invention. Therefore, the embodiments disclosed in the present invention are intended to illustrate rather than limit the technical idea of ​​the present invention, and the scope of the technical idea of ​​the present invention is not limited by these embodiments. The scope of protection of the present invention should be interpreted by the following claims, and all technical ideas within a scope equivalent thereto should be interpreted as being included in the scope of the rights of the present invention.

Claims

1. (a) A step of extracting gluten meal from corn; (b) a step of extracting natural additives from spinach, bean sprouts and soybeans; (c) a step of preparing a first gluten wheat reaction solution in which alkaline protein is decomposed by mixing an alkaline protein-decomposing enzyme into gluten wheat; (d) a step of mixing a neutral protein-decomposing enzyme into the first gluten wheat reaction solution to prepare a second gluten wheat reaction solution in which neutral protein is decomposed; (e) obtaining a powder form of an oligopeptide from the second gluten wheat reaction solution; and (f) a step of preparing an alcohol decomposition accelerator by mixing oligopeptides and natural additives; A method for producing an alcohol decomposition accelerator, characterized in that it comprises:

2. In paragraph 1, Step (a) above, (a1) A step of drying corn at a temperature of 105℃ to 125℃ to remove moisture and grinding it into a powder having particles of 400㎛ or less; (a2) A step of diluting 5 to 15 parts by weight of corn powder with respect to 100 parts by weight of water, allowing it to settle for 20 to 40 minutes, and obtaining gluten flour formed in the upper layer of the sediment; (a3) A step of preparing a gluten wheat mixture by mixing 10 to 15 parts by weight of gluten wheat with 100 parts by weight of water; (a4) A step of adding hydroxide to a gluten wheat mixture to adjust the pH of the gluten wheat mixture to 9 to 10, and extracting solid gluten wheat from the pH-adjusted gluten wheat mixture; (a5) A step of purifying and filtering the gluten wheat solid by adding 100 L of washing water (water) per 10 kg to 12 kg of gluten wheat to a stirrer and stirring at a temperature of 50°C to 80°C for 60 to 90 minutes; (a6) a step of concentrating the refined and filtered gluten wheat and drying the concentrated gluten wheat; and (a7) A step of selecting high-purity gluten wheat containing 85 wt% or more of protein; A method for producing an alcohol decomposition accelerator, characterized in that it comprises:

3. In paragraph 1, Step (b) above, (b1) A step of removing moisture contained in spinach, bean sprouts and soybeans, and grinding the spinach, bean sprouts and soybeans from which moisture has been removed; (b2) a step of extracting vitamin B6 from crushed spinach powder; and (b3) A step of extracting vitamin B1, vitamin B2 and amino acids from soybean sprouts and soybean powder, respectively; A method for producing an alcohol decomposition accelerator, characterized in that it comprises:

4. In paragraph 1, Step (c) above, (c1) A step of preparing a gluten wheat mixture by adding 8 to 12 parts by weight of alkaline protein decomposition enzyme to 100 parts by weight of gluten wheat; (c2) a step of adding a hydroxide brine solution to the above gluten wheat mixture to set the pH to 7 to 9; and (c3) A step of preparing a first gluten wheat reaction solution by heating a mixture of pH 7 to 9 to 45 to 60°C while stirring and reacting for 3 to 10 hours; A method for producing an alcohol decomposition accelerator, characterized in that it comprises:

5. In paragraph 4, The above alkaline proteolytic enzyme A method for producing an alcohol decomposition accelerator, characterized in that it is one or a mixture of two or more of papain, aloe vera extract, bromelain, and panthenone.

6. In paragraph 1, Step (d) above, (d1) A step of adjusting the pH of the first gluten wheat reaction solution to 5 to 5.5 by adding 4 to 20 parts by weight of water to 100 parts by weight of the first gluten wheat reaction solution; (d2) A step of adding 0.5 to 5 parts by weight of a neutral protein decomposing enzyme to 100 parts by weight of the first gluten wheat reaction solution in which pH adjustment has been made; (d3) a step of adjusting the pH to 6 to 8 by adding hydrochloric acid to the first gluten wheat reaction solution to which neutral protein decomposition enzyme has been added; and (d4) A step of preparing a second gluten wheat reaction solution by reacting the first gluten wheat reaction solution with added neutral protein decomposition enzyme at 35°C to 55°C and stirring for 3 to 10 hours; A method for producing an alcohol decomposition accelerator, characterized in that it comprises:

7. In paragraph 6, The above neutral protein-decomposing enzyme is, A method for producing an alcohol decomposition promoter characterized by using either Lactobacillus acidophilus or Saccharomyces cerevisiae.

8. In paragraph 1, Step (e) above, (e1) A step of mixing an extraction solvent into the second gluten wheat reaction solution, heating and stirring at a temperature of 40°C to 60°C for 20 to 24 hours, and then centrifuging to separate the solid phase and the liquid phase; (e2) A step of filtering the separated liquid and adjusting the pH of the filtered filtrate to 7 to 9; (e3) A step of purifying the filtrate in which pH adjustment has been made; (e4) a step of concentrating the purified filtrate to obtain an oligopeptide; and (e5) A step of drying the obtained oligopeptide to prepare it in powder form; A method for producing an alcohol decomposition accelerator, characterized in that it comprises:

9. In paragraph 8, The above powdered oligopeptide is, A method for producing an alcohol decomposition promoter, characterized in that the crude protein content is 85% by weight or more and the low molecular weight is 1,000 Da or less.

10. In paragraph 1, Step (f) above, A method for producing an alcohol decomposition promoter, characterized in that the alcohol decomposition promoter is produced by mixing 25 to 40 parts by weight of amino acids and 0.1 to 0.9 parts by weight of a vitamin B complex including vitamin B1, vitamin B2, and vitamin B6 per 100 parts by weight of oligopeptide.

11. In paragraph 10, A method for producing an alcohol decomposition promoter, characterized in that the above vitamin B complex is composed of vitamin B1, vitamin B2, and vitamin B6 in a weight ratio of 1:1:3.

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