Pharmaceutical formulation compatibility testing apparatus
By introducing a meshing structure of large and small gears into the drug compatibility experimental device, combined with the use of a micro water pump, the problem of drug residue was solved, the drug solution was fully compatible and the pipeline was cleaned, ensuring the repeatability and accuracy of the experiment.
Patent Information
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Filing Date
- 2024-09-30
- Publication Date
- 2026-04-02
AI Technical Summary
Existing drug compatibility testing equipment is prone to producing drug residues, which can affect the accuracy of subsequent experiments.
A drug compatibility experimental device was designed. The meshing connection of a large gear and a small gear drives the large turbine blades and the small turbine blades to rotate, generating agitation to promote drug compatibility. After the experiment, a micro water pump and a high-pressure water pipe are used to flush the pipeline to remove residual drugs.
This effectively avoids reagent residues, ensures the accuracy and reliability of subsequent experiments, and improves the reusability of the experimental apparatus.
Smart Images

Figure CN2024122708_02042026_PF_FP_ABST
Abstract
Description
A pharmaceutical preparation compatibility experimental device TECHNICAL FIELD
[0001] The present application relates to the technical field of pharmaceutical preparation compatibility, in particular to a pharmaceutical preparation compatibility experimental device. BACKGROUND
[0002] The pharmaceutical preparation compatibility experimental device is a rapid detection technology, which is widely used in medical diagnosis, food safety, environmental monitoring and other fields. The pharmaceutical preparation compatibility experimental device is mainly composed of a large turbine fan blade, a small turbine fan blade, a micro water pump, a temperature sensor and a corrosion-resistant rubber pipe. Its working principle is to pull out the second plug from the water inlet pipe, pour pure water, start the heating device to heat the pure water, control the pure water in the device box through the temperature sensor, pour the liquid medicine into the liquid medicine hopper, flow into the corrosion-resistant rubber pipe through the straight pipe under the action of the first electromagnetic valve, and make the pure water produce agitation through the rotation of the large turbine fan blade and the small turbine fan blade, so as to make the corrosion-resistant rubber pipe shake and promote the compatibility of the liquid medicine. When the liquid medicine completes the experiment, the straight pipe, the corrosion-resistant rubber pipe and the first connecting pipe will produce residual medicine, which is not conducive to the next experiment. By opening the second electromagnetic valve, starting the micro water pump to make the pure water in the pure water tank enter through the high-pressure water pipe and the second connecting pipe, and flushing the straight pipe, the corrosion-resistant rubber pipe and the first connecting pipe.
[0003] SUMMARY
[0004] In view of the defects of the prior art, the present application provides a pharmaceutical preparation compatibility experimental device, which solves the problem of residual medicine in the existing pharmaceutical preparation compatibility experimental device, which is not conducive to the next experiment.
[0005] To achieve the above purpose, the following technical scheme is adopted: a pharmaceutical preparation compatibility experimental device, comprising: a device box, the lower surface of the device box is fixedly connected with supporting legs, the number of the supporting legs is multiple and uniformly distributed, the bottom inner wall of the device box is fixedly connected with a supporting piece, the inner wall of the supporting piece is fixedly connected with a heating device, the upper surface of the device box is fixedly connected with a driving motor, the lower end of the driving motor is provided with a first rotating shaft, the top inner wall of the device box is fixedly connected with a first fixing piece, the lower surface of the first fixing piece is fixedly connected with a mounting ring, the lower surface of the first rotating shaft is fixedly connected with a large gear, the outer surface of the large gear is meshed with a small gear, and the upper surface of the small gear is fixedly connected with a second rotating shaft.
[0006] The rear surface of the device box is fixedly connected with a support plate, the upper surface of the support plate is fixedly connected with a purified water tank, the upper end of the purified water tank is provided with a micro water pump, the upper end of the micro water pump is provided with a high-pressure water pipe, the front end of the high-pressure water pipe is provided with a second electromagnetic valve, the front end of the second electromagnetic valve is provided with a second connecting pipe, the front surface of the second connecting pipe is fixedly connected with a straight-through pipe, the lower surface of the straight-through pipe is fixedly connected with a corrosion-resistant rubber pipe, the front surface of the corrosion-resistant rubber pipe is fixedly connected with a first connecting pipe, the upper surface of the device box is provided with a third hole, the inner wall of the third hole is fixedly connected with a first electromagnetic valve, and the upper surface of the first electromagnetic valve is fixedly connected with a liquid medicine hopper.
[0007] Preferably, the lower end of the device box is provided with a drain pipe, and the inner wall of the drain pipe is provided with a first plug.
[0008] Preferably, the input end of the heating device is electrically connected with an external power supply, the number of the support members is multiple and uniformly distributed.
[0009] Preferably, the inner wall of the side of the device box is fixedly connected with a temperature sensor, and the input end of the temperature sensor is electrically connected with an external power supply.
[0010] Preferably, the upper end of the device box is provided with a water inlet pipe, and the inner wall of the water inlet pipe is provided with a second plug.
[0011] Preferably, the upper surface of the device box is provided with a first hole, and the inner wall of the first hole is in contact with a first rotating shaft.
[0012] Preferably, the upper surface of the mounting ring is provided with a second hole, and the inner wall of the second hole is in contact with a second rotating shaft.
[0013] Preferably, the upper surface of the second rotating shaft is fixedly connected with a limiting piece, and the lower surface of the limiting piece is in contact with the mounting ring.
[0014] Preferably, the lower surface of the large gear is fixedly connected with a second fixed shaft, and the outer surface of the second fixed shaft is fixedly connected with a large turbine blade.
[0015] Preferably, the lower surface of the small gear is fixedly connected with a first fixed shaft, and the outer surface of the first fixed shaft is fixedly connected with a small turbine blade.
[0016] The application provides a pharmaceutical formulation compatibility experiment device.
[0017] The inside of the drug preparation compatibility experiment device is provided with a shaking structure, the pure water is fully compatible through shaking, the second fixed shaft fixedly connected to the lower surface of the large gear is provided with a large turbine blade, the first fixed shaft fixedly connected to the lower surface of the small gear is provided with a small turbine blade, the pure water is stirred through the rotation of the large turbine blade and the small turbine blade, so that the corrosion-resistant rubber pipe is shaken, and the drug compatibility is promoted, when the drug liquid completes the experiment, the straight-through pipe, the corrosion-resistant rubber pipe and the first connecting pipe will produce drug residues, which is not conducive to the next experiment, by opening the second electromagnetic valve, the pure water in the pure water tank is pumped into the high-pressure water pipe and the second connecting pipe through the micro water pump, and the straight-through pipe, the corrosion-resistant rubber pipe and the first connecting pipe are flushed, so that the influence on the next experiment is avoided. BRIEF DESCRIPTION OF DRAWINGS
[0018] Fig. 1 is a schematic diagram of the overall structure of the present application;
[0019] Fig. 2 is a schematic diagram of the internal structure of the present application;
[0020] Fig. 3 is a schematic diagram of the shaking structure of the present application;
[0021] Fig. 4 is a detailed view of the structure of the present application;
[0022] Fig. 5 is a schematic diagram of the meshing connection structure of the present application;
[0023] Fig. 6 is a schematic diagram of the cleaning structure of the present application.
[0024] 1, device box; 2, drain pipe; 3, first plug; 4, support; 5, heating device; 6, driving motor; 7, water inlet pipe; 8, second plug; 9, first rotating shaft; 10, first fixing piece; 11, mounting ring; 12, first hole; 13, second hole; 14, second rotating shaft; 15, limiting piece; 16, large gear; 17, small gear; 18, small turbine blade; 19, first fixed shaft; 20, large turbine blade; 21, second fixed shaft; 22, support plate; 23, third hole; 24, liquid medicine bucket; 25, first electromagnetic valve; 26, straight-through pipe; 27, high-pressure water pipe; 28, corrosion-resistant rubber pipe; 29, first connecting pipe; 30, micro water pump; 31, pure water tank; 32, second connecting pipe; 33, second electromagnetic valve; 34, support leg; 35, temperature sensor. DETAILED DESCRIPTION
[0025] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor are within the scope of protection of the present application.
[0026] As shown in Figures 1-6, the embodiment of the present application provides a kind of drug preparation compatibility experimental device, including, device box 1, the lower surface of device box 1 is fixedly connected with support leg 34, the number of support leg 34 is multiple and evenly distributed, the bottom inner wall of device box 1 is fixedly connected with support piece 4, the inner wall of support piece 4 is fixedly connected with heating device 5, the upper surface of device box 1 is fixedly connected with drive motor 6, the lower end of drive motor 6 is provided with first rotating shaft 9, the top inner wall of device box 1 is fixedly connected with first fixed part 10, the lower surface of first fixed part 10 is fixedly connected with mounting ring 11, the lower surface of first rotating shaft 9 is fixedly connected with large gear 16, the outer surface of large gear 16 is meshingly connected with small gear 17, the upper surface of small gear 17 is fixedly connected with second rotating shaft 14.
[0027] The rear surface of device box 1 is fixedly connected with support plate 22, the upper surface of support plate 22 is fixedly connected with pure water tank 31, the upper end of pure water tank 31 is provided with micro water pump 30, the upper end of micro water pump 30 is provided with high-pressure water pipe 27, the front end of high-pressure water pipe 27 is provided with second electromagnetic valve 33, the front end of second electromagnetic valve 33 is provided with second connecting pipe 32, the front surface of second connecting pipe 32 is fixedly connected with straight-through pipe 26, the lower surface of straight-through pipe 26 is fixedly connected with corrosion-resistant rubber tube 28, the front surface of corrosion-resistant rubber tube 28 is fixedly connected with first connecting pipe 29, the upper surface of device box 1 is provided with third hole 23, the inner wall of third hole 23 is fixedly connected with first electromagnetic valve 25, the upper surface of first electromagnetic valve 25 is fixedly connected with liquid medicine hopper 24, the lower end of device box 1 is provided with drain pipe 2, the inner wall of drain pipe 2 is provided with first plug 3, the input end of heating device 5 is electrically connected with external power supply, the number of support piece 4 is multiple and evenly distributed, the side inner wall of device box 1 is fixedly connected with temperature sensor 35, the input end of temperature sensor 35 is electrically connected with external power supply, the upper end of device box 1 is provided with water inlet pipe 7, the inner wall of water inlet pipe 7 is provided with second plug 8, the upper surface of device box 1 is provided with first hole 12, the inner wall of first hole 12 is in contact with first rotating shaft 9, the upper surface of mounting ring 11 is provided with second hole 13, the inner wall of second hole 13 is in contact with second rotating shaft 14, the upper surface of second rotating shaft 14 is fixedly connected with limit piece 15, the lower surface of limit piece 15 is in contact with mounting ring 11, the lower surface of large gear 16 is fixedly connected with second fixed shaft 21, the outer surface of second fixed shaft 21 is fixedly connected with large turbine blade 20, the lower surface of small gear 17 is fixedly connected with first fixed shaft 19, the outer surface of first fixed shaft 19 is fixedly connected with small turbine blade 18.
[0028] Working principle: the second plug 8 from the water pipe 7, pour pure water, start heating device 5 to heat the pure water, through the temperature sensor 35 to the device box 1 in the pure water control, liquid medicine through the liquid bucket 24 into, under the action of the first electromagnetic valve 25 through the straight pipe 26 into the corrosion-resistant rubber tube 28, start drive motor 6 drive first rotating shaft 9 rotation, first rotating shaft 9 drive gear 16 rotation, gear 16 outer surface through the meshing connection pinion 17 rotation, in order to improve the rotation of the pinion 17, the second rotating shaft 14 fixedly connected with the upper end of the pinion 17 through the second hole 13 and installation ring 11 rotation connection, and uses the limiting piece 15 for limiting, the lower surface of the gear 16 fixedly connected with the second fixed shaft 21 is provided with large turbine blade 20, the lower surface of the pinion 17 fixedly connected with the first fixed shaft 19 is provided with small turbine blade 18, through the rotation of the large turbine blade 20 and small turbine blade 18 makes pure water produces agitating, so as to make corrosion-resistant rubber tube 28 shake, promote liquid medicine compatibility, when the liquid medicine completes the experiment, straight pipe 26, corrosion-resistant rubber tube 28 and first connecting pipe 29 will produce the residue of the medicament, is not conducive to the next experiment, by opening the second electromagnetic valve 33, start micro water pump 30 pure water water tank 31 in the pure water through the high pressure water pipe 27 and second connecting pipe 32 into and flush straight pipe 26, corrosion-resistant rubber tube 28 and first connecting pipe 29.
[0029] Although embodiments of the present application have been shown and described, it is to be understood that various modifications, substitutions, alternatives and variations can be made to these embodiments without departing from the principles and spirit of the present application, the scope of which is defined by the appended claims and their equivalents.
Claims
1. A pharmaceutical formulation compatibility experiment apparatus, characterized by, The application relates to a device box (1), the lower surface of the device box (1) is fixedly connected with supporting legs (34), the supporting legs (34) are uniformly distributed, the bottom inner wall of the device box (1) is fixedly connected with supporting pieces (4), the inner wall of the supporting pieces (4) is fixedly connected with a heating device (5), the upper surface of the device box (1) is fixedly connected with a driving motor (6), the lower end of the driving motor (6) is provided with a first rotating shaft (9), the top inner wall of the device box (1) is fixedly connected with a first fixing piece (10), the lower surface of the first fixing piece (10) is fixedly connected with a mounting ring (11), the lower surface of the first rotating shaft (9) is fixedly connected with a large gear (16), the outer surface of the large gear (16) is meshingly connected with a small gear (17), and the upper surface of the small gear (17) is fixedly connected with a second rotating shaft (14). The rear surface of the device box (1) is fixedly connected with a supporting plate (22), the upper surface of the supporting plate (22) is fixedly connected with a pure water tank (31), the upper end of the pure water tank (31) is provided with a micro water pump (30), the upper end of the micro water pump (30) is provided with a high-pressure water pipe (27), the front end of the high-pressure water pipe (27) is provided with a second electromagnetic valve (33), the front end of the second electromagnetic valve (33) is provided with a second connecting pipe (32), the front surface of the second connecting pipe (32) is fixedly connected with a straight-through pipe (26), the lower surface of the straight-through pipe (26) is fixedly connected with a corrosion-resistant rubber pipe (28), the front surface of the corrosion-resistant rubber pipe (28) is fixedly connected with a first connecting pipe (29), the upper surface of the device box (1) is provided with a third hole (23), the inner wall of the third hole (23) is fixedly connected with a first electromagnetic valve (25), and the upper surface of the first electromagnetic valve (25) is fixedly connected with a liquid medicine hopper (24). The lower end of the device box (1) is provided with a drain pipe (2), and the inner wall of the drain pipe (2) is provided with a first plug (3).
2. A pharmaceutical formulation compatibility assay device according to claim 1, wherein: The input end of the heating device (5) is electrically connected with an external power supply, and the supporting pieces (4) are uniformly distributed.
3. The pharmaceutical formulation compatibility assay device of claim 1, wherein: The side inner wall of the device box (1) is fixedly connected with a temperature sensor (35), and the input end of the temperature sensor (35) is electrically connected with an external power supply.
4. A pharmaceutical formulation compatibility test device according to claim 1, wherein: The upper end of the device box (1) is provided with a water inlet pipe (7), and the inner wall of the water inlet pipe (7) is provided with a second plug (8).
5. The pharmaceutical formulation compatibility assay device of claim 1, wherein: The upper surface of the device box (1) is provided with a first hole (12), and the inner wall of the first hole (12) is in contact with the first rotating shaft (9).
6. The pharmaceutical formulation compatibility assay device of claim 1, wherein: The upper surface of the mounting ring (11) is provided with a second hole (13), and the inner wall of the second hole (13) is in contact with the second rotating shaft (14).
7. The pharmaceutical formulation compatibility assay device of claim 1, wherein: The upper surface of the second rotating shaft (14) is fixedly connected with a limiting piece (15), and the lower surface of the limiting piece (15) is in contact with the mounting ring (11).
8. The pharmaceutical formulation compatibility assay device of claim 1, wherein: 9. The pharmaceutical formulation compatibility assay device of claim 1, wherein: The lower surface of the large gear (16) is fixedly connected with a second fixed shaft (21), and the outer surface of the second fixed shaft (21) is fixedly connected with a large turbine blade (20).
10. The pharmaceutical formulation compatibility assay device of claim 1, wherein: The lower surface of the small gear (17) is fixedly connected with a first fixed shaft (19), and the outer surface of the first fixed shaft (19) is fixedly connected with a small turbine blade (18).
Citation Information
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