The invention relates to a car door-window straight-line part gland strip and a preparation method, which iare used for solving the problem that the compression permanent deformation rate of the present car door-window straight-line part gland strip is high, and adopts the technical scheme that: the gland strip is prepared by the following substances in part by weight: 22 to 27 ethylene propylenediene rubber 9090M, 6 to 10 ethylene propylene diene rubber 3072EM, 1 to 3 active zinc oxide, 0.4 to 0.8 stearic acid, 0.4 to 1.0 dispersant L-24, 0.7 to 1.1 polyethyleneglycol, 25 to 30 general purpose furnace black (GPF)-grade carbon black N650, 10 to 14 heavy calcium carbonate, 16 to 20 paraffin oil, 1 to 3 calcium oxide, 1.3 to 1.7 accelerator, 0.05 to 0.08 antiscorching agent, 0.2 to 0.6 sulfur and 0.8 to 1.2 p,p'-Oxybis(benzenesulfonyl hydrazide) N8000W. The car door-window straight-line part gland strip has good elasticity, good aging resistance, excellent ozone property, good low-temperature application property and appropriate apparent density.