A kind of pharmaceutical composition for the treatment of chronic pelvic inflammatory disease and preparation method thereof

The technology of a chronic pelvic inflammatory disease and a composition is applied in the field of pharmaceutical compositions for the treatment of chronic pelvic inflammatory disease and the field of preparation thereof, which can solve the problem of increasing mental and economic burdens of patients, failing to achieve long-term curative effects, drug resistance or drug toxicity and side effects And other issues

Active Publication Date: 2017-07-21
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chronic pelvic inflammatory disease has a long course of disease and stubborn inflammation. Western medicine and antibiotic treatment often fail to achieve long-term efficacy, and drug resistance or drug side effects are prone to occur, which increases the mental and economic burden on patients.

Method used

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  • A kind of pharmaceutical composition for the treatment of chronic pelvic inflammatory disease and preparation method thereof
  • A kind of pharmaceutical composition for the treatment of chronic pelvic inflammatory disease and preparation method thereof
  • A kind of pharmaceutical composition for the treatment of chronic pelvic inflammatory disease and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0183] Embodiment 1: Granules

[0184] Saponaria thorn 12 Polygonum cuspidatum 8

[0185] Dandelion 9.6 Big blood vine 9.6

[0186] Codonopsis 12, Smilax 12.

[0187] Polygonum cuspidatum was soaked with 8 times the amount of 85% ethanol for 0.5 hours, extracted twice for 1.5 hours each time, the extract was filtered and concentrated to obtain the Polygonum cuspidatum extract;

[0188] Add 12 times water, soak for 0.5 hours, extract 2 times, 1.5 hours each time, concentrate the extract, place it at room temperature, sink to 50% with 95% ethanol , concentrating the supernatant, combining the Polygonum cuspidatum extract, concentrating, drying, and pulverizing into fine powder; adding an appropriate amount of microcrystalline cellulose and 1% aspartame to make granules.

Embodiment 2

[0189] Embodiment 2: tablet

[0190] Saponaria thorn 8 Polygonum cuspidatum 6

[0191] Dandelion 8 Big blood vine 8

[0192] Codonopsis 8, Smilax 8.

[0193] The above-mentioned six flavors are crushed into fine powder, sieved, added appropriate amount of starch and magnesium stearate, granulated, granulated, and compressed into tablets to obtain the product.

Embodiment 3

[0194] Embodiment 3: hard capsules

[0195] Saponaria thorn 15 Polygonum cuspidatum 10

[0196] Dandelion 12 Big blood vine 12

[0197] Codonopsis 15 and Sarsaparilla 15.

[0198] Add 12 times of water to the above-mentioned six flavors, soak for 0.5 hours, extract twice for 1.5 hours each time, dry, and pulverize into fine powder; add appropriate amount of starch, granulate with polyacrylic acid resin, and pack into capsules.

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Abstract

The invention discloses a pharmaceutical composition for gynecological pelvic inflammatory disease and a preparation method thereof. The pharmaceutical composition is made of the following crude drugs in parts by weight: 8-15 parts by weight of saponins, 6-10 parts by weight of Polygonum cuspidatum, dandelion 8 to 12 parts by weight, 8 to 12 parts by weight of Sarsaparilla, 8 to 15 parts by weight of Codonopsis, and 8 to 15 parts by weight of Smilax. The preparation method of the above medicine is also disclosed. The pharmaceutical composition of the invention can be applied to the preparation of medicine for treating chronic pelvic inflammatory disease.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a pharmaceutical composition for treating chronic pelvic inflammatory disease and a preparation method thereof. Background technique [0002] Pelvic inflammatory disease (Pelvic inflammatory disease, PID) is a group of diseases caused by inflammation of the female upper reproductive tract, including endometritis, salpingitis, tubo-ovarian abscess and pelvic peritonitis. At the same time, metritis, salpingo-oophoritis, pelvic connective tissue inflammation and pelvic peritonitis can occur in one or several places at the same time, which is one of the common diseases in women. Pelvic inflammatory disease is most likely to occur in middle-aged women aged 30 to 50, especially some office workers who are sedentary and lack of activity, resulting in slowed blood circulation, blocked pelvic venous return, and excessive blood stasis can also cause pelvic inflammatory disease. [0003] Pel...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/896A61K36/90A61P15/00
Inventor 萧伟王振中毕宇安钱俊吴云刘莉莉王星星徐海娟陈春苗张宏达
Owner JIANGSU KANION PHARMA CO LTD
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