Centrifugal filtering device and centrifugal equipment for pharmaceutical use

By designing a centrifugal filtration device including a stirring bucket, cyclone and centrifugal pump, the problem of inefficient separation efficiency of traditional equipment when processing different materials is solved, and efficient and low-cost material separation is achieved, suitable for the preparation of raw materials, etc. High precision production requirements.

CN118988578BActive Publication Date: 2025-02-07ANHUI SENJI PHARM CO LTD
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Patent Information

Application Number
CN202411458338.1
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-10-18
Publication Date
2025-02-07
Estimated Expiration
2044-10-18

AI Technical Summary

Technical Problem

When traditional centrifugal filtration equipment deals with materials with different viscosity, particle size and fluidity, the separation efficiency is low, easy to block, and high cost, making it difficult to meet the requirements for high-precision separation during the preparation of raw materials.

Method used

A device including a feed assembly and a centrifugal filtration assembly is designed. The feed assembly is equipped with a stirring bucket, crushing teeth, screen and conveying pipe. The material is realized through the synchronous transmission of the crushing teeth, conveying paddles and adapter blades. Mix evenly and initial screening. The centrifugal filtration assembly adopts a spiral swirl and a centrifugal pump to optimize the flow path and flowability of the material, and automatically discharge waste through a hollow vortex cylinder.

Benefits of technology

It significantly improves separation efficiency, reduces equipment operating costs, enhances material flowability and processing capacity, ensures efficient processing of high-viscosity materials and large-scale materials, and reduces equipment maintenance requirements and production costs.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention relates to a centrifugal filtering device, comprising a front-placed feeding component and a centrifugal filtering component mounted on a frame, wherein a stirring bucket and a transmission mechanism with a feeding port extending obliquely are mounted at the front of the feeding component, crushing teeth are horizontally penetrated in the stirring bucket, and a screen is embedded in the bottom of the stirring bucket, a semi-open conveying pipe with an inner rotating conveying paddle is arranged below the screen, a pipe head sleeve of the conveying pipe is provided with a "B"-shaped transfer bin, and a transfer leaf is suspended therein, the centrifugal filtering component comprises a baseball bat-shaped hollow centrifugal cylinder and a cylindrical collecting bin sleeved at the bottom thereof, a spiral vortex wing is attached to the chamber of the centrifugal cylinder, a centrifugal pump is embedded at the connection between a tangential receiving port extending horizontally at the end thereof and the feeding port, and a hollow vortex cylinder is penetrated and connected to the top wall of the chamber of the centrifugal cylinder, and the vortex cylinder is bent upward and extended to have a waste discharge port connected to the waste cylinder; the separation accuracy and efficiency are improved, and the smooth mass production of high-viscosity materials can be ensured.
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Description

Technical Field

[0001] The invention relates to the technical field of centrifugal filtration, in particular to a centrifugal filtration device and a centrifugal equipment for pharmaceutical use. Background Art

[0002] In the preparation process of API (Active Pharmaceutical Ingredient), filtration and separation operations are key links to ensure product purity and quality. Byproducts and impurities are often produced during the reaction process. If these substances are not effectively separated, they will affect the purity of the final product, and even affect the efficacy and safety. Therefore, accurate filtration technology is one of the core processes in the production of APIs, especially the separation and filtration of solid-solid particles. Centrifugal filtration technology has become the preferred method to solve this problem due to its advantages such as high efficiency, easy operation and strong adaptability. It is currently a widely used separation technology in the pharmaceutical and chemical industries. The working principle of centrifugal filtration technology is relatively simple: when the centrifugal cylinder inside the equipment rotates at high speed, it will generate a strong centrifugal force, which will throw the solid particles in the mixture to the cylinder wall. The particles will be deposited in different areas according to their diameter or density, so as to achieve the separation of solid particles. This technology can process large quantities of materials quickly and efficiently, especially when facing materials with similar particle sizes or small density differences, it can still maintain a high separation effect.

[0003] However, traditional centrifugal filtration equipment has exposed some obvious defects in practical applications. Traditional centrifugal filtration devices usually adopt a simple centrifugal cylinder structure, which does not fully consider the differences in material properties, especially when dealing with materials with different viscosities, particle sizes and different fluidities, and fail to optimize the design in a targeted manner. Due to the uneven force on solid particles inside the centrifugal cylinder, and the inability to effectively control the strength of the centrifugal force, solid particles are often easy to accumulate in the centrifugal cylinder, which leads to uneven distribution of materials and thus affects the overall separation effect. Especially when facing high-viscosity materials, the fluidity of the materials is poor, and it is difficult to smoothly distribute evenly in the centrifugal cylinder, resulting in a significant decrease in centrifugal filtration efficiency. With the improvement of product quality and production efficiency requirements in the API industry, the existing traditional centrifugal filtration equipment has been difficult to meet market demand. It is urgent to develop a new generation of centrifugal filtration equipment that can adapt to large-scale production, high-precision separation, and high stability through technological innovation to cope with the technical difficulties of solid-solid particle separation in the production process and meet the industry's urgent needs for efficient, low-cost, and refined production. Summary of the invention

[0004] In view of the shortcomings of the prior art, the present invention provides a centrifugal filter device and a pharmaceutical centrifugal device, and the specific technical scheme is as follows:

[0005] The present invention provides a centrifugal filtering device, comprising a front-placed feeding assembly and a centrifugal filtering assembly mounted on a frame, wherein a stirring bucket and a transmission mechanism with a feeding port obliquely extended are mounted at the front of the feeding assembly, a crushing tooth is horizontally penetrated in the stirring bucket, and a screen is embedded at the bottom thereof, a semi-open conveying pipe with an inner rotating conveying paddle is arranged below the screen, a pipe head sleeve of the conveying pipe is provided with a "b"-shaped transfer bin, in which a transfer leaf is suspended, a top of the transfer bin is bent and extended with a transverse feeding port, and the crushing tooth, the conveying paddle and the transfer leaf are synchronously driven by the transmission mechanism, The centrifugal filtration component includes a baseball bat-shaped hollow centrifugal cylinder and a cylindrical collection bin mounted at the bottom thereof, the bottom of the collection bin is in an inverted cone shape, a spiral vortex wing is attached to the chamber of the centrifugal cylinder, a tangential receiving port laterally extending at the end thereof is detachably connected to the feeding port, and a centrifugal pump is embedded at the connection, which can drive the particles in the transfer bin to enter the centrifugal cylinder tangentially and rotate downward at high speed along the spiral vortex wing, and a hollow vortex cylinder is penetrated and connected to the top wall of the centrifugal cylinder chamber, and the vortex cylinder is bent upward and extended to have a waste discharge port connected to the waste cylinder, which is used to filter and collect impurities in the particles.

[0006] As a preferred technical solution of the present invention, the crushing teeth are an "X"-shaped composite fork frame with dual-axis connection transmission, the screen is a rubber screen, and the crushing teeth rotate and elastically contact the screen to stir and screen particles of uniform size into the centrifugal filter device;

[0007] Oversized materials fall into the screen, and the crushing teeth continue to rotate, stir and crush them, so that they are completely crushed and pass through.

[0008] As a preferred technical solution of the present invention, the transfer blades of the transfer bin are radially composed of six equally spaced trapezoidal blades, which are used for rotating and stirring the particles to reach the feeding port.

[0009] As a preferred technical solution of the present invention, the cyclone wing is made of elastic material, and its spiral pitch can be changed along the spiral direction to adapt to particles of different specific gravities. A magnet is attached to its outer peripheral surface and can move up and down along the inner wall of the centrifugal cylinder to adjust the height of impurity suction.

[0010] As a preferred technical solution of the present invention, a docking flange is provided on the lower circumference of the centrifugal cylinder, which is fixed to the collecting bin by bolts for maintenance and replacement of the centrifugal cylinder.

[0011] As a preferred technical solution of the present invention, a discharge valve is provided at the lowest point of the inverted conical bottom of the aggregate bin for effectively discharging the finished particles.

[0012] As a preferred technical solution of the present invention, the frame is symmetrically provided with stabilizing beams and shock-absorbing beams in the upper and lower parts, which are used to filter the vibration generated by the centrifugal filter cylinder.

[0013] As a preferred technical solution of the present invention, a waste pump is buried in the waste outlet of the centrifugal cylinder, which can effectively draw out impurities from the centrifugal filtration center axis to improve the efficiency of centrifugal filtration of impurities.

[0014] As a preferred technical solution of the present invention, the feed port of the feed assembly is connected to the receiving port of the centrifugal filter assembly by a snap-fit ​​connection.

[0015] The beneficial effects of the present invention are:

[0016] The centrifugal filter device provided by the present invention has effectively improved the problems of high cost, low efficiency, easy clogging and the like in the prior art centrifugal filtration, and has significant beneficial effects. The device includes a front feed assembly and a centrifugal filter assembly mounted on a frame. The front of the feed assembly is provided with a stirring bucket and a transmission mechanism with an obliquely extended feed port. The stirring bucket is provided with crushing teeth, which can achieve uniform mixing of materials and effectively avoid the problem of uneven separation caused by material accumulation in traditional devices. At the same time, a screen is embedded at the bottom of the stirring bucket, and a semi-open conveying pipe with an inwardly rotating conveying paddle is provided below the screen. Through the synchronous transmission of the crushing teeth, the conveying paddle and the transfer blade, it is ensured that the material is fully mixed and preliminarily screened before entering the centrifugal filter assembly, laying a solid foundation for subsequent efficient filtration.

[0017] Compared with the simple centrifugal barrel structure of the traditional centrifugal filter device, the present invention adopts a more advanced design, in which a spiral swirl wing is attached to the chamber of the centrifugal barrel to guide and optimize the flow path of the material. Under the action of centrifugal force, the material moves downward along the spiral swirl wing, avoiding the problems of material accumulation and uneven distribution in traditional equipment, thereby greatly improving the separation efficiency. Through the design of the spiral swirl wing, the material can be evenly distributed in the centrifugal barrel and sink in an orderly manner along the spiral trajectory, making full use of the centrifugal force for particle separation. This improvement effectively solves the problem of low separation efficiency of traditional devices when processing materials with high viscosity or similar particle diameters, so that it can better adapt to the requirements for high-precision separation in the preparation process of raw materials.

[0018] In addition, the centrifugal filter device of the present invention further optimizes the fluidity of the material by introducing a centrifugal pump. The centrifugal pump is installed between the feed port and the transfer bin. Through the action of the centrifugal pump, the particulate material can be tangentially flushed into the centrifugal cylinder and rotated at high speed along the spiral flow wing. Compared with the traditional single action mode relying on gravity and centrifugal force, this device has better performance in guiding the fluidity of the material, ensuring the continuity and efficiency of the material throughout the filtration process. Not only does it increase the speed of particle separation, it can also better cope with the processing needs of high-viscosity materials and large quantities of materials, thereby greatly reducing the operating cost of the equipment and improving production efficiency.

[0019] In terms of waste treatment, the present invention realizes the automatic discharge of waste through the design of the hollow vortex cylinder. The hollow vortex cylinder that penetrates and is connected to the top wall of the centrifugal cylinder chamber can effectively filter and separate impurities and waste, and discharge them through the waste discharge port that bends and extends upward. Traditional centrifugal filtering devices often have problems with waste retention and poor discharge, resulting in frequent equipment cleaning and maintenance needs. The present invention ensures the timely discharge of waste and avoids equipment blockage and shutdown problems through a reasonable waste discharge system design. The physical structure design not only reduces manual operation, but also reduces the frequency of equipment maintenance during the production process, further reducing production costs.

[0020] At the same time, the synchronous transmission mechanism of the present invention can realize the synchronous movement of the crushing teeth, conveying paddles and transfer leaves, ensuring the uniform flow and efficient screening of materials. Traditional centrifugal filtration equipment usually has uneven transmission, resulting in uneven material distribution and low filtration efficiency. The synchronous transmission design can coordinate the operation of various components to ensure the consistency and stability of the material throughout the filtration process, avoiding equipment loss and poor separation effect caused by vibration, noise and other problems during equipment operation. It not only improves the stability of the equipment, but also effectively reduces the energy consumption of the equipment, allowing it to continue to operate efficiently in a high-intensity production environment.

[0021] In summary, the present invention overcomes several shortcomings in the prior art and has significant beneficial effects through the optimized design of the structure of the centrifugal filter device. First, the separation accuracy and efficiency are improved through the efficient separation of materials through mixed crushing, preliminary screening and spiral cyclone wings; secondly, the introduction of the centrifugal pump enhances the fluidity and processing capacity of the material, ensuring the smooth mass production of high-viscosity materials; thirdly, the automatic waste discharge system effectively solves the problems of equipment blockage and waste retention, reducing downtime and maintenance costs; finally, the synchronous transmission design improves the stability and energy efficiency of the equipment, making it more economical and practical in high-standard production processes such as API preparation. Therefore, the device provides a more ideal solution to the problem of high-cost centrifugal filtration in the API preparation process. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 The overall structural schematic diagram of the present invention is shown;

[0023] Figure 2 A schematic diagram of the three-dimensional structure of the feed assembly in the present invention is shown;

[0024] Figure 3 An exploded view of the feed assembly of the present invention is shown;

[0025] Figure 4 A schematic diagram of the three-dimensional structure of the centrifugal filter assembly and the frame assembly of the present invention is shown;

[0026] Figure 5 A front view of the centrifugal filter assembly and the frame assembly of the present invention is shown;

[0027] Figure 6 Shows Figure 5 Schematic diagram of the cross-sectional structure of the middle AA part;

[0028] Figure 7 A three-dimensional perspective view of a centrifugal cylinder in the present invention is shown;

[0029] Figure 8 The three-dimensional structure schematic diagram of the swirl wing in the present invention is shown;

[0030] As shown in the figure: 1. Feed assembly; 11. Transmission mechanism; 12. Mixing bucket; 121. Feed port; 122. Screen; 13. Crushing teeth; 14. Conveying pipe; 141. Conveying paddle; 15. Transfer bin; 151. Transfer blade; 152. Feed port; 16. Centrifugal pump; 2. Centrifugal filtration assembly; 21. Centrifugal cylinder; 211. Receiving port; 212. Waste outlet; 213. Docking flange; 214. Swirl wing; 215. Vortex cylinder; 22. Collecting bin; 221. Discharge valve; 23. Waste cylinder; 231. Waste pump; 3. Frame; 31. Stabilizing beam; 32. Shock-absorbing beam. DETAILED DESCRIPTION

[0031] In order to make the purpose, technical solution and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with the embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0032] Embodiment 1

[0033] In order to solve the technical problems in the background technology, a centrifugal filter device and a pharmaceutical centrifugal device are provided as follows:

[0034] Combination Figure 1-7As shown, a centrifugal filtering device comprises a front feed assembly 1 and a centrifugal filtering assembly 2 mounted on a frame 3, wherein a stirring bucket 12 and a transmission mechanism 11 are mounted at the front of the feed assembly 1, a crushing tooth 13 is horizontally penetrated in the stirring bucket 12, and a screen 122 is embedded at the bottom thereof, a semi-open conveying pipe 14 with an inner rotating conveying paddle 141 is arranged below the screen 122, a pipe head sleeve of the conveying pipe 14 is provided with a "b"-shaped transfer bin 15, a transfer leaf 151 is suspended therein, a top of the transfer bin 15 is bent and extended with a horizontal feed port 152, and the crushing tooth 13, the conveying paddle 141 and the transfer leaf 151 are connected to the transmission mechanism 11 at the same time. The centrifugal filter assembly 2 includes a baseball bat-shaped hollow centrifugal cylinder 21 and a cylindrical collecting bin 22 mounted at the bottom thereof. The bottom of the collecting bin 22 is inverted cone-shaped. A spiral vortex wing 214 is attached to the chamber of the centrifugal cylinder 21. A tangential receiving port 211 extending laterally at the end thereof is detachably connected to the feeding port 152, and a centrifugal pump 16 is embedded at the connection, which can drive the particles in the transfer bin 15 to enter the centrifugal cylinder 21 tangentially and rotate downward along the spiral vortex wing 214 at high speed. A hollow vortex cylinder 215 is penetrated and connected to the top wall of the chamber of the centrifugal cylinder 21. The vortex cylinder is bent upward and extends to have a waste outlet 212 connected to the waste cylinder 23, which is used to filter and collect impurities in the particles.

[0035] Through the above technical scheme, the device has effectively improved the problems of high cost, low efficiency, easy clogging and so on in the prior art centrifugal filtration, and has significant beneficial effects. The device includes a pre-feeding assembly 1 and a centrifugal filtration assembly 2 mounted on a frame 3. The front of the feeding assembly 1 is equipped with a stirring bucket 12 and a transmission mechanism 11 with an obliquely extended feed port 121. The stirring bucket 12 is provided with crushing teeth 13, which can achieve uniform mixing of materials and effectively avoid the problem of uneven separation caused by material accumulation in traditional devices. At the same time, a screen 122 is embedded at the bottom of the stirring bucket 12, and a semi-open conveying pipe 14 with an inner rotating conveying paddle 141 is provided below the screen 122. Through the synchronous transmission of the crushing teeth 13, the conveying paddle 141 and the transfer blade 151, it is ensured that the material is fully mixed and preliminarily screened before entering the centrifugal filtration assembly 2, which lays a solid foundation for subsequent efficient filtration.

[0036] Compared with the simple centrifugal cylinder 21 structure of the traditional centrifugal filter device, this device adopts a more advanced design, and a spiral swirl wing 214 is attached to the chamber of the centrifugal cylinder 21 to guide and optimize the flow path of the material. Under the action of centrifugal force, the material moves downward along the spiral wing 214, avoiding the problems of material accumulation and uneven distribution in traditional equipment, thereby greatly improving the separation efficiency. Through the design of the spiral swirl wing 214, the material can be evenly distributed in the centrifugal cylinder 21, and sink in an orderly manner along the spiral trajectory, making full use of the centrifugal force for particle separation. This improvement effectively solves the problem of low separation efficiency of traditional devices when processing materials with high viscosity or similar particle diameters, so that it can better adapt to the requirements for high-precision separation in the preparation process of raw materials.

[0037] In addition, the device further optimizes the fluidity of the material by introducing the centrifugal pump 16. The centrifugal pump 16 is installed between the feed port 152 and the transfer bin 15. Through the action of the centrifugal pump 16, the particulate material can be tangentially flushed into the centrifugal cylinder 21 and rotated at high speed along the spiral flow wing 214. Compared with the traditional single action mode relying on gravity and centrifugal force, the device has better performance in guiding the fluidity of the material, ensuring the continuity and efficiency of the material in the entire filtration process. Not only does it increase the speed of particle separation, it can also better cope with the processing needs of high-viscosity materials and large quantities of materials, thereby greatly reducing the operating cost of the equipment and improving production efficiency.

[0038] In terms of waste treatment, this device realizes the automatic discharge of waste through the design of the hollow vortex cylinder 215. The hollow vortex cylinder 215 that penetrates and is connected to the top wall of the chamber of the centrifugal cylinder 21 can effectively filter and separate impurities and waste, and discharge them through the waste outlet 212 that bends and extends upward. Traditional centrifugal filtration devices often have problems with waste retention and poor discharge, resulting in frequent equipment cleaning and maintenance needs. However, this device ensures the timely discharge of waste through a reasonable waste discharge system design, avoiding equipment blockage and shutdown problems. The physical structure design not only reduces manual operation, but also reduces the frequency of equipment maintenance during the production process, further reducing production costs.

[0039] At the same time, the synchronous transmission mechanism 11 of the device can realize the synchronous movement of the crushing teeth 13, the conveying paddle 141 and the transfer blade 151, ensuring the uniform flow and efficient screening of the material. Traditional centrifugal filtration equipment usually has uneven material distribution and low filtration efficiency due to uneven transmission, while the synchronous transmission design can coordinate the operation of various components to ensure the consistency and stability of the material throughout the filtration process, avoiding equipment loss and poor separation effect caused by vibration, noise and other problems during equipment operation. It not only improves the stability of the equipment, but also effectively reduces the energy consumption of the equipment, allowing it to continue to operate efficiently in a high-intensity production environment.

[0040] In summary, this device overcomes many shortcomings in the prior art through the optimized design of the centrifugal filtration structure and has significant beneficial effects. First, the separation accuracy and efficiency are improved through the efficient separation of materials through mixed crushing, preliminary screening and spiral cyclone wings 214; secondly, the introduction of the centrifugal pump 16 enhances the fluidity and processing capacity of the materials, ensuring the smooth mass production of high-viscosity materials; thirdly, the automatic waste discharge system effectively solves the problems of equipment blockage and waste retention, reducing downtime and maintenance costs; finally, the synchronous transmission design improves the stability and energy efficiency of the equipment, making it more economical and practical in high-standard production processes such as API preparation. Therefore, the device provides a more ideal solution to the problem of high-cost centrifugal filtration in the API preparation process.

[0041] As a preferred embodiment, a discharge valve 221 is provided at the lowest point of the inverted conical bottom of the collecting bin 22 for effectively discharging the finished particles.

[0042] Embodiment 2

[0043] like Figure 2-3 As shown, based on the above embodiment, this embodiment further provides the following contents:

[0044] In this embodiment, the crushing teeth 13 are an "X"-shaped composite fork frame with a double-axis connection transmission, and the screen 122 is a rubber screen 122. The crushing teeth 13 rotate and elastically contact with the screen 122 to stir and screen particles of uniform size to enter the centrifugal filter device;

[0045] The oversized materials fall into the screen 122, and the crushing teeth 13 continue to rotate, stir and crush them, so that they are completely crushed and pass through.

[0046] In the preparation process of APIs, centrifugal filtration is a key link that determines the purity of the product and the uniformity of the particles. However, traditional centrifugal filtration technology has some obvious defects, such as unstable screening efficiency, uneven finished product particle size, and unsatisfactory filtration effect. These problems will directly affect the quality and production efficiency of the product, especially in the preparation of high-precision APIs, the limitations of centrifugal filtration technology are particularly prominent. Traditional centrifugal filters usually rely on a single centrifugal device to separate particles, and this method has high requirements for particle size consistency. However, due to factors such as differences in particle size and the single centrifugal process, traditional equipment often encounters problems such as particle clogging of the device and inconsistent finished products when processing diversified raw materials, resulting in a decrease in filtration accuracy and reduced production efficiency.

[0047] In order to solve these problems, the combination of the innovatively designed "X"-shaped composite fork frame of the dual-axis connection transmission and the elastic material screen 122 provides a new solution for centrifugal filtration. Through the above technical solution, this front design significantly improves the efficiency and accuracy of filtration, and is particularly suitable for the high-precision requirements in the preparation of raw materials. First of all, the "X"-shaped composite fork frame design of the dual-axis connection transmission has structural advantages. The "X"-shaped design of the fork frame can provide stable coaxial rotation stirring, which enables the crushing teeth 13 to achieve a more flexible motion trajectory during operation. Compared with the traditional single-axis transmission, this design can more evenly apply the stirring and crushing effect to the material, effectively avoiding the problem of particle accumulation and uneven distribution in the subsequent centrifugal filtration process. At the same time, the dual-axis transmission ensures the balanced distribution of the stirring torque, further improving the uniformity of the material particle mixing. Especially in the pharmaceutical process, the size and shape of the particles are crucial to the quality of the drug. This uniform stirring design ensures the consistency of the particle screening process, thereby improving the quality of the final product.

[0048] Secondly, the screen 122 is made of elastic material, and this design greatly improves the flexibility and durability of the filtration. Traditional centrifugal filters usually do not have a pre-screen 122, which is prone to wear, deformation, and even rupture during long-term use due to high-intensity centrifugal filtration, resulting in a decrease in filtration efficiency and frequent maintenance of the equipment. The pre-elastic screen 122 has strong compression and tensile resistance, and can achieve adaptive deformation during stirring and crushing, avoiding the accumulation and clogging of particles on the screen 122. At the same time, the elastic screen 122 can also achieve further screening and separation of particles through elastic contact with the crushing teeth 13, and synchronous vibration and rebound during the stirring process. This dynamic contact method is more effective than traditional centrifugal filters. It not only effectively improves the screening accuracy, but also enhances the durability and stability of the screen 122 in long-term use, greatly reducing the maintenance requirements of the equipment.

[0049] In addition, this design also makes up for the shortcomings of traditional equipment in handling high-viscosity and high-humidity materials. When traditional centrifugal filtration equipment directly handles high-viscosity and high-humidity raw materials, it often has problems such as poor filtration and clogging of the screen 122. This innovative design effectively avoids these problems through the dual-axis crushing of the crushing teeth 13 and the elastic deformation of the screen 122. After stirring and screening, the material can quickly enter the centrifugal separation stage and will not stay on the screen 122 for too long, thereby improving the overall filtration efficiency.

[0050] In summary, the stirring bucket 12 has significantly overcome the shortcomings of traditional technologies through innovative structural design and material selection, and has obvious advantages in improving screening accuracy, extending equipment life, and reducing maintenance costs. This design provides reliable technical support for high-precision centrifugal filtration in the preparation of raw materials, and can significantly improve production efficiency and final product quality.

[0051] Embodiment 3

[0052] like Figure 3-8 As shown, based on the above embodiment, this embodiment further provides the following contents:

[0053] In this embodiment, the swirl wing 214 is made of elastic material, and its spiral pitch can be changed along the spiral direction to adapt to particles of different specific gravities. A magnet is attached to its outer peripheral surface, and it can move up and down along the inner wall of the centrifugal cylinder 21 to adjust the height of impurity suction.

[0054] A waste pump 231 is embedded in the waste outlet 212 of the centrifugal drum 21, which can effectively remove impurities from the centrifugal filtration center axis, so as to improve the efficiency of centrifugal filtration of impurities.

[0055] In the preparation process of APIs, centrifugal filtration is one of the key steps. However, the existing technology often faces problems such as insufficient filtration accuracy and incomplete impurity removal when dealing with particles of different densities. The fixed structure of the traditional centrifugal filter is difficult to adapt to the physical properties of different types of particles, especially when dealing with particles with large differences in specific gravity, the filtration effect is not ideal. In addition, the suction height of impurities is usually fixed and cannot be dynamically adjusted according to actual needs, resulting in some impurities remaining or too much raw material being sucked out, affecting the purity and yield of the final product. Such problems not only lead to a decrease in filtration efficiency, but may also affect the purity of the final product. Traditional technology generally relies on a single centrifugal force to drive impurities to be discharged to the outer wall, but this method is not effective under high viscosity and complex particle systems. Impurities are easily retained in key positions, resulting in frequent cleaning and maintenance of equipment, reducing production efficiency.

[0056] In response to these problems, the new centrifugal filtration design effectively overcomes the above drawbacks by introducing a swirl wing 214. Through the above technical solution, first, the swirl wing 214 is made of elastic material, and its spiral pitch can be adjusted according to the density of different particles, so that the distribution of centrifugal force is more uniform and adapts to particles of different specific gravities. This design greatly improves the filtration accuracy, ensures the effective separation of impurities and raw materials, and reduces the filtration deviation caused by differences in particle characteristics. Secondly, a magnet is attached to the outer peripheral surface of the swirl wing 214, which can move up and down along the inner wall of the centrifuge barrel 21. This design allows the impurity suction height to be flexibly adjusted, avoiding the problem of impurity residue or raw material loss that may be caused by a fixed suction position. Through this dynamic adjustment, the filtration process can be controlled more accurately to ensure that impurities are thoroughly sucked out while retaining the effective ingredients of the raw materials to the maximum extent.

[0057] The role of the waste pump 231 is another important technical innovation in the whole system. The waste pump 231 is buried in the waste outlet 212 of the centrifugal drum 21, and effectively discharges the impurities swirling at the central axis by active drainage. Traditional centrifugal filtering equipment relies on centrifugal force to screen out impurities, but for impurities swirling at the central axis position, the effect of centrifugal force is weak, which makes it difficult to effectively discharge impurities in these areas. The waste pump 231 can provide additional drainage power, specifically suck out the impurities near the central axis and discharge them out of the system, significantly improving the efficiency of impurity filtration. The central axis is usually a high-incidence area for impurity accumulation, and the waste pump 231 can be specifically processed for this weak link, ensuring that the impurities in the equipment will not accumulate in a concentrated manner, and maintaining the efficiency and stability of the centrifugal filtration process.

[0058] In addition, this design has good adaptability to various types of materials. Whether it is a high-viscosity material or a mixture containing a large amount of tiny impurities, the combination of the swirl wing 214 and the waste pump 231 can be flexibly adjusted according to the different characteristics of the material. The up and down movement of the swirl wing 214 and the adjustment of the spiral pitch allow impurities to be sucked out at different heights and widely applicable to particles of different specific gravities, ensuring the accuracy and efficiency of the filtration. The active waste discharge function of the waste pump 231 further enhances the stability of the system, and both large particles and fine impurities can be effectively discharged, ensuring the consistency and thoroughness of the filtering effect. This design can significantly improve the operating efficiency of the production line in the pharmaceutical field, especially in the preparation of high-precision raw materials, and reduce the risk of quality problems caused by residual impurities.

[0059] In summary, the magnetically attached and flexible adjustment design of the swirl wing 214 and the application of the waste pump 231 greatly improve the performance and adaptability of the centrifugal filtration equipment. Compared with traditional filtration technology, this innovative design not only overcomes the problem of impurity retention and the difficulty of removing impurities from the central axis, but also significantly improves the efficiency of impurity filtration and the continuity of equipment operation. This provides a new solution for efficient centrifugal filtration in the preparation process of raw materials, which not only improves the purity and quality of the product, but also reduces the maintenance cost of the equipment, providing solid technical support for efficient production in the pharmaceutical industry.

[0060] Embodiment 4

[0061] like Figure 2-3 As shown, based on the above embodiment, this embodiment further provides the following contents:

[0062] In this embodiment, the transfer blades 151 of the transfer bin 15 are radially composed of six equally spaced trapezoidal blades, and are used for rotating and stirring particles to reach the feeding port 152 .

[0063] The feed port 152 of the feed assembly 1 is connected to the receiving port 211 of the centrifugal filter assembly 2 via a buckle.

[0064] In the preparation process of raw materials, centrifugal filtration technology plays a vital role and is directly related to the purity and production efficiency of the product. However, traditional centrifugal filtration technology has certain shortcomings in the process of particle conveying and filtration docking, especially in terms of uneven particle conveying and unstable docking. These problems not only affect the filtration efficiency, but also easily lead to discontinuity in equipment operation, thereby reducing the overall production efficiency. Traditional equipment often relies on gravity or simple mechanical conveying methods to transport raw materials from the feed port 121 to the centrifugal filtration component 2, but this design usually leads to uneven particle distribution, affecting the subsequent filtration effect. Especially in high-precision production, the uniform conveying of particles and the stable docking of channels are crucial to filtration efficiency and product quality.

[0065] In response to these problems, a radial arrangement design of six equally spaced trapezoidal blades in the transfer bin 15 is adopted. Through the above technical solution, this design greatly optimizes the way the particles are transported. In traditional centrifugal filtration equipment, the transportation of particles is often not uniform, especially when the transportation speed is inconsistent, some particles may accumulate or be unevenly distributed, thus affecting the subsequent filtration process. The six equally spaced trapezoidal blades can achieve uniform transportation of particles through rotary stirring. Not only does the structure ensure the uniform distribution of particles, but also through its special shape and equidistant arrangement, it effectively avoids the accumulation of particles due to gravity during the transportation process. Through continuous rotary stirring, the particles can be more evenly transported to the feed port 152, thereby ensuring the consistency of particle distribution in the subsequent centrifugal filtration process.

[0066] In addition, the design of six trapezoidal blades also improves the efficiency of conveying through rotational motion. In traditional equipment, the particle conveying process may be affected by speed and material characteristics, resulting in unstable particle conveying speed. However, through this rotary stirring design, the trapezoidal blades can apply uniform force to the particles while rotating, so that the particles maintain a stable state of motion during the conveying process. This stable conveying method not only improves production efficiency, but also reduces the loss and friction damage of particles during the conveying process, further improving the quality and yield of the product.

[0067] In addition, a snap-on connection is adopted between the feed component 1 and the centrifugal filter component 2 that match this design, which provides a reliable guarantee for the stable operation of the equipment. The traditional docking method of the feed and filter components is often loose, which is easy to cause loose connection due to equipment vibration or material characteristics, thereby affecting the particle conveying efficiency or causing material leakage. The snap-on connection ensures the precise docking between the feed port 121 and the receiving port 211 through a tighter and more stable structural design. This not only prevents the loss of materials during the particle conveying process, but also ensures the stability of the equipment operation and reduces production interruptions caused by component misalignment or looseness. In addition, the snap-on connection design simplifies the installation and maintenance process of the equipment, and workers can complete the docking or disassembly of the equipment more quickly, thereby shortening the time for equipment maintenance and cleaning and improving the overall operation efficiency of the production line.

[0068] These structural designs not only excel in uniform particle delivery and equipment docking, but also effectively solve the common clogging and leakage problems in traditional centrifugal filtration equipment. Due to the stirring effect of the trapezoidal blades, the particles can maintain continuous fluidity during the conveying process and are not prone to clogging due to accumulation or friction. At the same time, the snap-on connection method ensures the tight docking of the conveying component and the filtration component, effectively avoiding leakage caused by improper docking. This design greatly reduces material loss in the production process, improves resource utilization, and also provides strong support for improving the economic benefits of production.

[0069] Compared with traditional technology, this design of six trapezoidal blades and snap-on connection has brought significant technological improvement. Traditional equipment often relies on a single conveying method during particle conveying, which cannot effectively ensure the uniform distribution of particles and the stability of conveying speed. This innovative design not only improves the uniformity of conveying by rotating and stirring particles, but also ensures the seamless connection between feeding and filtration processes through snap-on connection, thereby effectively improving the overall operating efficiency of the equipment. In the preparation process of raw materials, stable conveying and efficient filtration of particles are crucial to ensure the purity and consistency of the product. This design is based on the optimization of these key links, providing a guarantee for an efficient and stable production process.

[0070] In summary, the application of six equally spaced trapezoidal blades and the snap-on connection design in centrifugal filtration not only overcomes the shortcomings of traditional equipment in particle conveying and docking, but also significantly improves the continuity, stability and efficiency of the production process. Through this design, particles can be more evenly conveyed to the filtration stage, avoiding the decline in filtration effect due to uneven distribution. At the same time, the snap-on connection ensures the stability of equipment operation and reduces maintenance requirements and production interruptions.

[0071] Embodiment 5

[0072] like Figure 3-8 As shown, based on the above embodiment, this embodiment further provides the following contents:

[0073] In this embodiment, a docking flange 213 is provided on the lower circumference of the centrifugal cylinder 21 , and the docking flange 213 is bolted to the collecting bin 22 for maintenance and replacement of the centrifugal cylinder 21 .

[0074] The frame 3 is symmetrically provided with a stabilizing beam 31 and a shock absorbing beam 32 in upper and lower parts, and is used to filter the vibration generated by the centrifugal filter cylinder.

[0075] In the process of API preparation, the stability and convenience of centrifugal filtration devices are important factors that determine production efficiency and product quality. However, traditional centrifugal filtration equipment usually has defects such as excessive equipment vibration and inconvenient installation and maintenance in actual applications. These problems will not only affect the stability of the filtration process, but also increase equipment wear and maintenance difficulties, thereby having a negative impact on the continuity and efficiency of production. Especially when running at high speed, the violent vibration generated by the centrifugal drum 21 will cause the overall operating stability of the equipment to decrease, and it is easy to have loose parts and unstable filtering effects. In addition, the maintenance and replacement of traditional equipment often requires the disassembly of a large number of parts, and the process is cumbersome and time-consuming, which not only increases the maintenance cost, but also affects the continuity and efficiency of production.

[0076] In response to these problems, a design is introduced in which a docking flange 213 is provided on the lower circumference of the centrifugal cylinder 21, and the docking flange 213 is bolted to the aggregate bin 22. Through the above technical solution, the convenience of the equipment during maintenance and replacement is greatly improved. The cylinder body of traditional centrifugal filtration equipment is usually connected to other components by welding or riveting. When disassembling, multiple parts need to be disassembled, which is complicated to operate and easy to cause secondary damage to the equipment. The design of the docking flange 213 allows the centrifugal cylinder 21 to be quickly docked and separated from the aggregate bin 22. During maintenance and replacement, it only takes unscrewing the bolts to complete the quick disassembly and assembly. It not only reduces the time cost during the disassembly and assembly of the equipment, but also reduces the complexity of manual operation, effectively improving the maintenance efficiency and reliability of the equipment. At the same time, the design also reduces the risk of component wear caused by frequent disassembly and extends the service life of the equipment.

[0077] In addition, the application of the docking flange 213 also improves the overall sealing and operational stability of the equipment. Through the tight connection of the flange bolts, the close docking of the centrifugal cylinder 21 and the collection bin 22 can be ensured, avoiding the occurrence of leakage and uneven filtration caused by loose connections. Compared with traditional welding or riveting fastening methods, flange connection can provide more stable support without sacrificing sealing, so that the equipment can still maintain good stability and durability during long-term high-speed centrifugal filtration. This design provides an important guarantee for the stable operation of the centrifugal filter device at high speeds, significantly reduces the vibration and noise of the equipment during high-intensity work, and helps to improve the filtration accuracy of the product and the safety of the production environment.

[0078] In the optimized design for the vibration problem during the operation of the equipment, the stabilizing beam 31 and the shock absorbing beam 32 symmetrically arranged on the upper and lower parts of the frame 3 also play a key role. In the traditional centrifugal filtration device, the vibration generated when the centrifugal cylinder 21 rotates at high speed is difficult to be effectively absorbed and eliminated, which often leads to excessive vibration of the entire equipment, which not only affects the filtration effect, but also may cause fatigue damage and shorten the service life of the equipment. Especially when processing large batches of materials, the problem of equipment vibration will be more obvious. The design of the stabilizing beam 31 and the shock absorbing beam 32 is symmetrically arranged on the upper and lower parts of the frame 3, which effectively disperses and absorbs the vibration generated during the centrifugal filtration process. The stabilizing beam 31 provides additional structural support to ensure that the equipment remains balanced and stable when rotating at high speed; the shock absorbing beam 32 absorbs the vibration energy and reduces the amplitude to a safe range, thereby reducing the impact of equipment vibration on the filtration effect.

[0079] Compared with the single shock-absorbing design of traditional equipment, the combination of the stabilizing beam 31 and the shock-absorbing beam 32 arranged symmetrically up and down can more comprehensively offset the multi-directional vibrations generated during the centrifugal filtration process, so that the equipment can still maintain a good operating state during high-speed centrifugal filtration, avoiding the risk of equipment wear, loose components and even equipment failure caused by excessive vibration, and effectively reducing the noise pollution during equipment operation, providing more comfortable operating conditions for the production environment.

[0080] In summary, the combined design of the flange 213 on the lower circumference of the centrifugal cylinder 21, the stabilizing beam 31 and the shock-absorbing beam 32 has significant advantages in improving the convenience of equipment maintenance and operational stability. Compared with traditional equipment, this design greatly simplifies the installation and maintenance process of the equipment, reduces the complexity and time cost of manual operation, reduces equipment wear and maintenance frequency, and thus significantly improves production efficiency. At the same time, the coordinated use of the stabilizing beam 31 and the shock-absorbing beam 32 effectively solves the vibration problem when the equipment is running at high speed, and provides a strong guarantee for the stability and filtration accuracy during the centrifugal filtration process. This innovative design not only improves the overall performance of the equipment, but also reduces the risk of equipment failure under high load conditions, and provides a more efficient and stable solution for centrifugal filtration in the preparation process of raw materials, and has good application prospects and promotion value.

[0081] The working principle and use process of the present invention:

[0082] 1. Equipment preparation and inspection

[0083] Before starting the centrifugal filter device, you first need to conduct a comprehensive inspection of the equipment. Check whether the centrifugal filter assembly 2 on the frame 3 and the front feed assembly 1 are firmly fixed, and ensure that key components such as the mixing bucket 12, transmission mechanism 11, centrifugal cylinder 21, and collection bin 22 are not loose or damaged. At the same time, check whether the crushing teeth 13 in the mixing bucket 12 of the feed assembly 1 are installed correctly, whether the screen 122 is intact, and whether the inner rotating conveying paddle 141 of the conveying pipe 14 and the transfer blades 151 in the transfer bin 15 can rotate flexibly. Confirm that the magnet can move up and down along the inner wall of the centrifugal cylinder 21 for subsequent adjustment. Finally, ensure that the power connection of the equipment is normal, and check whether the power systems such as the centrifugal pump 16 and the waste pump 231 are operating normally.

[0084] 2. Feed preparation

[0085] Prepare the particulate material to be filtered and pour it into the feed port 121 of the mixing bucket 12 of the feed assembly 1. The crushing teeth 13 inserted in the mixing bucket 12 start rotating and stirring, and elastically contact the elastic screen 122 at the bottom, and cooperate with the stirring and crushing to screen out particles with relatively uniform particle sizes through the screen 122 into the semi-open conveying pipe 14 below. At this time, the transmission mechanism 11 drives the transfer blade 151 and the conveying paddle 141 to work synchronously to avoid the subsequent conveying process being affected by the blockage of particles. Impurities or oversized particles that fail to meet the screening requirements will remain in the mixing bucket 12, and will be stirred and crushed in a cycle until they pass the screen 122.

[0086] 3. Particle transport

[0087] The screened particles enter the "b"-shaped transfer bin 15 through the conveying pipe 14. In the transfer bin 15, six trapezoidal transfer blades 151 are radially distributed in an equidistant manner. After the blades rotate to further stir and mix the particles, the materials are evenly conveyed to the feeding port 152 and are ready to enter the centrifugal filter device.

[0088] 4. Centrifugal filtration

[0089] The granular material enters the centrifugal filter assembly 2 through the feed port 152. At this time, the feed port 152 is firmly connected to the receiving port 211 of the centrifugal filter assembly 2 through a buckle to ensure that the material can smoothly enter the centrifugal cylinder 21. Driven by the centrifugal pump 16, the material enters the receiving port 211 in a spiral manner along the swirl wing 214 and spirally rotates downward at high speed. This swirl motion separates impurities in the granular material and finished particles due to differences in diameter and density. During the centrifugal filtration process, the height of the magnet attached to the outer peripheral surface of the swirl wing 214 can be adjusted as needed to control the height of impurities sucked out, thereby improving the filtration accuracy.

[0090] 5. Impurity discharge

[0091] When the particulate material rotates and separates in the centrifugal drum 21, the impurities circle around the central axis of the centrifugal drum 21. The impurities enter the waste drum 23 through the waste outlet 212. The waste outlet 212 of the centrifugal drum 21 is also equipped with a waste pump 231, which can speed up the extraction of impurities at the central axis and further improve the efficiency of impurity separation.

[0092] 6. Finished particle collection

[0093] After the particles are separated from the impurities, the finished particles gradually settle to the inverted cone bottom of the collection bin 22 and finally gather at the lowest point of the inverted cone bottom. The discharge valve 221 is opened to discharge the finished particles from the collection bin 22.

[0094] 7. Equipment maintenance and cleaning

[0095] After completing the entire filtering process, the equipment needs to be maintained and cleaned. First, turn off the power to ensure that the equipment is completely stopped. Secondly, disassemble the snap-on connection and clean the remaining particles and impurities in the feed port 152, the transfer bin 15, the centrifuge cylinder 21 and other components. Then the aggregate bin 22 and the discharge valve 221 at the bottom of the inverted cone also need to be cleaned to prevent particle accumulation during the next use. Finally, check the shock-absorbing beam 32 and the stabilizing beam 31 of the frame 3 to ensure that the equipment remains stable during operation and reduce the interference of vibration on the filtering effect.

[0096] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A centrifugal filtering device, comprising a front feed assembly (1) and a centrifugal filtering assembly (2) mounted on a frame (3), wherein a stirring bucket (12) with a feed port (121) extending obliquely and a transmission mechanism (11) are mounted on the front of the feed assembly (1), a crushing tooth (13) is transversely penetrated in the stirring bucket (12), and a screen (122) is embedded in the bottom thereof, a semi-open conveying pipe (14) with an inner rotating conveying paddle (141) is arranged below the screen (122), and the conveying pipe (14) The pipe head sleeve is provided with a "b"-shaped transfer bin (15), in which a transfer leaf (151) is suspended, the top of the transfer bin (15) is bent and extended to have a transverse feeding port (152), and the crushing teeth (13), the conveying paddle (141) and the transfer leaf (151) are synchronously driven by the transmission mechanism (11), the centrifugal filter assembly (2) comprises a baseball bat-shaped hollow centrifugal cylinder (21) and a cylindrical material collection bin (22) sleeved at the bottom thereof, the bottom of the material collection bin (22) is in an inverted cone shape, and is characterized in that: A spiral vortex wing (214) is attached to the chamber of the centrifugal cylinder (21), and a tangential material receiving port (211) extending laterally from the end of the centrifugal cylinder (21) is detachably connected to the material feeding port (152). A hollow vortex cylinder (215) is connected through the top wall of the chamber of the centrifugal cylinder (21), and a centrifugal pump (16) is embedded at the connection point, which can drive the particles in the transfer bin (15) to enter the centrifugal cylinder (21) tangentially and rotate downward along the spiral vortex wing (214) at high speed. The vortex cylinder (215) is bent upward and extended to have a waste discharge port (212) connected to the waste cylinder (23), which is used to filter and collect impurities in the particles. The crushing teeth (13) are an "X"-shaped composite fork frame with a double-shaft connection transmission, and the screen (122) is a rubber screen (122). When the crushing teeth (13) rotate, they elastically contact the screen (122) and are used to stir and screen materials. Particles of uniform size enter the centrifugal filter device, and oversized materials fall into the screen (122). The crushing teeth (13) continue to rotate, stir and crush, and completely crush and pass through. The cyclone wings (214) are made of elastic material and can change their spiral pitch along the spiral direction to accommodate particles of different specific gravities. A magnet is attached to the outer peripheral surface of the cyclone wings (214) and can move up and down along the inner wall of the centrifugal cylinder (21) to adjust the height of impurities suction.

2. A centrifugal filter device according to claim 1, characterized in that: The transfer blade (151) of the transfer bin (15) is composed of six equally spaced trapezoidal blades radially arranged to rotate and stir particles to reach the feeding port (152).

3. A centrifugal filter device according to claim 1, characterized in that: The lower circumferential surface of the centrifugal cylinder (21) is provided with a docking flange (213), which is bolted to the collecting bin (22) via the docking flange (213) and is used for maintenance and replacement of the centrifugal cylinder (21).

4. A centrifugal filter device according to claim 3, characterized in that: A discharge valve (221) is provided at the lowest point of the inverted conical bottom of the collecting bin (22) for effectively discharging the finished particles.

5. A centrifugal filter device according to claim 1, characterized in that: The frame (3) is symmetrically provided with a stabilizing beam (31) and a shock absorbing beam (32) arranged in an upper and lower manner, and is used to filter vibrations generated by a centrifugal filter cylinder.

6. A centrifugal filter device according to claim 3, characterized in that: A waste discharge port (212) of the centrifugal cylinder (21) is embedded with a waste discharge pump (231), which can effectively discharge impurities from the centrifugal filter center shaft.

7. A centrifugal filter device according to claim 6, characterized in that: The feeding port (152) of the feeding assembly (1) and the receiving port (211) of the centrifugal filtering assembly (2) are connected via a buckle.

8. A centrifugal device for pharmaceutical use, characterized in that: It comprises the centrifugal filtration device as described in any one of claims 1 to 7, wherein the pharmaceutical centrifugal equipment is used for stirring, crushing, filtering and screening medicinal raw materials.

Citation Information

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