Safety monitoring method based on irradiation sterilization

Abstract

The invention relates to the technical field of irradiation sterilization, in particular to a safety monitoring method based on irradiation sterilization, which comprises the following steps: closing a box door; detecting the actual leakproofness between the box door and the box body, judging whether the box door and the box body are closed or not, and determining to turn on the sterilizing lamp group or adjust the actual leakproofness between the box door and the box body according to a judgment result; based on a comparison result of the real-time working parameters and the preset working parameters of the sterilizing lamp group, judging a safety evaluation value of the lamp group; determining an environmental safety evaluation value based on the real-time environmental parameters and preset environmental parameters; adjusting the real-time working parameters of the sterilizing lamp group based on the lamp group safety evaluation value and the environment safety evaluation value; the to-be-sterilized sample is sterilized according to the adjusted sterilizing lamp set, the sterilizing effect of the sterilized to-be-verified sample is detected, and the preset working parameters are adjusted or sterilization is completed on the basis of comparison between the sterilizing effect and a preset effect. The safety of the sterilization environment in the sterilization process is improved.

Description

Technical Field

[0001] The invention relates to the technical field of radiation sterilization, and in particular to a safety monitoring method based on radiation sterilization. Background Art

[0002] With the continuous development of modern medical technology, sterilization technology has become an important part of ensuring medical safety. Although traditional sterilization methods such as high-temperature steam sterilization and chemical sterilization are widely used, they have problems such as cumbersome operation and unstable sterilization effect in some cases. Radiation sterilization technology is gradually being used due to its high efficiency, environmental protection and applicability to a wide range of materials. However, during the radiation sterilization process, how to accurately monitor the sterilization effect and ensure the safety and reliability of sterilization has become a problem that needs to be solved urgently.

[0003] The patent document with Chinese patent application number CN117139765A discloses a safe and controllable new VHP sterilization process, which is applied to the sterilization system. The sterilization system includes a monitoring system, a control system and a hydrogen peroxide generator. The monitoring system is equipped with a built-in probe and can be equipped with up to four remote probes. The control system is equipped with an automatic speed regulator. The monitoring system and the control system can be wirelessly connected through a smart mobile terminal. The hydrogen peroxide generator uses a spray-first and then cavity heating vaporization process to spray sterilization gas. The sterilization gas is generated by vaporizing a 35% hydrogen peroxide solution.

[0004] Although monitoring and control systems are configured in the prior art, they mainly focus on the generation and transmission process of hydrogen peroxide gas, and relatively little on the real-time environment and equipment status monitoring during the sterilization process, which can easily lead to low safety problems during the sterilization process. Summary of the invention

[0005] To this end, the present invention provides a safety monitoring method based on irradiation sterilization, which can solve the problem of low real-time safety of the sterilization process by real-time monitoring and analyzing key parameters in the sterilization process and adjusting the sterilization process according to these parameters.

[0006] To achieve the above object, the present invention provides a safety monitoring method based on irradiation sterilization, the method comprising:

[0007] Place the samples to be sterilized on the shelf in the sterilization box and close the door;

[0008] Detect the actual tightness between the box door and the box body, determine whether it is airtight according to the actual tightness test result, and determine to turn on the sterilization lamp group or adjust the actual tightness between the box door and the box body according to the judgment result;

[0009] The sterilization lamp group sterilizes the sample to be sterilized based on preset working parameters, detects the working parameters of the sterilization lamp group in real time, obtains the real-time working parameters, and determines the safety evaluation value of the lamp group based on the comparison result between the real-time working parameters and the preset working parameters;

[0010] Real-time monitoring of the environmental parameters inside the box during the sterilization process, obtaining the real-time environmental parameters, and determining the environmental safety evaluation value based on the real-time environmental parameters and preset environmental parameters;

[0011] Adjusting the real-time working parameters of the sterilization lamp group based on the judgment result of the lamp group safety evaluation value and the preset lamp group evaluation value and / or the judgment result of the environmental safety evaluation value and the preset environmental safety evaluation value;

[0012] The sample to be sterilized is sterilized according to the adjusted sterilization lamp group, the sterilization effect of the sterilized sample to be verified after the sterilization is completed is detected, and based on the comparison between the sterilization effect and the preset effect, it is determined whether the preset working parameters are adjusted or the sterilization is completed.

[0013] Furthermore, the step of detecting the actual airtightness between the box door and the box body comprises:

[0014] Monitor the internal pressure value of the box in real time, obtain the real-time pressure value, and draw a pressure change graph based on the real-time pressure value;

[0015] Obtaining a pressure change rate based on a pressure change graph, comparing the pressure change rate with a preset rate change range, and obtaining a rate comparison result;

[0016] The actual airtightness between the box door and the box body is determined based on the rate comparison result.

[0017] Furthermore, the step of real-time detection of the working parameters of the sterilization lamp group includes:

[0018] Detecting the power value of the sterilization lamp group in real time based on a power sensor to obtain a real-time power value;

[0019] Based on the lamp group temperature sensor, the temperature value of the sterilization lamp group is detected in real time to obtain the real-time temperature value of the lamp group;

[0020] The light intensity sensor detects the irradiance intensity value of the sterilization lamp group in real time to obtain the real-time irradiance intensity value.

[0021] Furthermore, the step of determining the safety evaluation value of the lamp group based on the comparison result of the real-time working parameter and the preset working parameter includes:

[0022] Draw a power change graph based on the real-time power value, analyze the power change graph, and determine a power safety evaluation value according to the analysis result of the power change graph;

[0023] Draw a temperature change graph based on the real-time temperature value of the lamp group, analyze the temperature change graph, and determine a temperature safety evaluation value according to the analysis result of the temperature change graph;

[0024] Draw an intensity change graph based on the real-time irradiation intensity value, analyze the intensity change graph, and determine the intensity safety evaluation value according to the analysis result of the intensity change graph;

[0025] Analyze the power change graph, the temperature change graph, and the strength change graph, determine the influence relationship among power, temperature, and strength according to the analysis results, and determine the scoring weight values ​​corresponding to the power safety evaluation value, the temperature safety evaluation value, and the strength safety evaluation value respectively based on the influence relationship;

[0026] The lamp group safety evaluation value is determined based on the power safety evaluation value, the temperature safety evaluation value, the intensity safety evaluation value and the scoring weight value.

[0027] Furthermore, the step of determining the power safety evaluation value according to the analysis result of the power change diagram includes:

[0028] Identifying the fluctuation frequency and fluctuation amplitude in the power variation graph;

[0029] Calculating fluctuation stability based on a comparison result between the fluctuation frequency and a preset fluctuation frequency and a comparison result between the fluctuation amplitude and a preset fluctuation amplitude;

[0030] The power safety evaluation value is calculated based on the fluctuation stability.

[0031] Furthermore, the step of determining the influence relationship between power, temperature and intensity according to the analysis result includes:

[0032] Calculate the correlation coefficient between any two of the power, the temperature and the intensity based on the Pearson correlation coefficient;

[0033] An influence relationship among the power, the temperature and the intensity is determined based on a plurality of the correlation coefficients.

[0034] Furthermore, the step of determining the environmental safety evaluation value based on the real-time environmental parameters and the preset environmental parameters includes:

[0035] Real-time detection of the ambient temperature and air density inside the box during the sterilization process;

[0036] Calculating an environmental temperature evaluation value based on a comparison result between the environmental temperature value and a preset temperature value;

[0037] Calculating an air density evaluation value based on a comparison result between the air density value and a preset density value;

[0038] The environmental safety evaluation value is calculated based on the environmental temperature evaluation value and the air density evaluation value.

[0039] Furthermore, the step of adjusting the real-time working parameters of the sterilization lamp group based on the judgment result between the lamp group safety evaluation value and the preset lamp group evaluation value and / or the judgment result between the environmental safety evaluation value and the preset environmental safety evaluation value includes:

[0040] When the lamp group safety evaluation value is greater than the preset lamp group evaluation value and / or the environmental safety evaluation value is greater than the preset environmental evaluation value, it is determined that the sterilization lamp group is in an abnormal state, and the real-time working parameters of the sterilization lamp group are adjusted down until the lamp group safety evaluation value or the environmental safety evaluation value meets the requirements and stops.

[0041] Furthermore, the step of adjusting the preset working parameters based on the comparison between the sterilization effect and the preset effect includes:

[0042] When the sterilization effect does not match the preset effect, determining the difference between the sterilization effect and the preset effect;

[0043] When the sterilization effect is stronger than the preset effect, reducing the preset working parameter according to the difference;

[0044] When the sterilization effect is lower than the preset effect, the preset working parameter is increased according to the difference.

[0045] Furthermore, the step of reducing the preset working parameters according to the difference comprises:

[0046] Dividing the difference by the standard value corresponding to the preset effect, and taking the result as the reduction amplitude;

[0047] The preset working parameters are adjusted based on the reduction range to obtain adjusted sterilization parameters.

[0048] Compared with the prior art, the beneficial effects of the present invention lie in that, by detecting the actual airtightness between the box door and the box body, the complete sealing of the sterilization box is ensured, radiation leakage is prevented, the safety of the sterilization process is guaranteed, and the sterilization effect of the samples to be sterilized is improved; by real-time detection of the working parameters of the sterilization lamp group, an accurate data basis is provided for the safety detection of the sterilization process to ensure the effectiveness of the sterilization process; by real-time monitoring of the environmental parameters inside the box during the sterilization process, the safety of the sterilization process environment is ensured; based on the real-time working parameters and environmental parameters, the safety of the lamp group and the environment is evaluated to comprehensively ensure the safety of the sterilization process and the effectiveness of the sterilization process is improved; according to the safety evaluation value of the lamp group and the environmental safety evaluation value, the real-time working parameters of the sterilization lamp group are adjusted to optimize the sterilization process and ensure the safety of the sterilization process; by performing a sterilization effect test on the sterilized samples to be verified after the sterilization is completed, the preset working parameters are adjusted or the sterilization is confirmed to be completed according to the test results, to provide an accurate data basis for the next sterilization process and improve the safety of the next sterilization process.

[0049] In particular, by real-time monitoring of the pressure value inside the box and drawing a pressure change graph, the pressure change trend over time can be intuitively displayed, which helps to identify possible leakage points. The pressure change rate can be obtained based on the pressure change graph and compared with the preset rate change range. It can further confirm whether the airtightness meets the requirements and comprehensively judge the actual airtightness between the box door and the box body, ensuring that the sterilization box is completely sealed, which helps to improve the effectiveness of the sterilization process, prevent radiation leakage, and improve the safety of the sterilization process.

[0050] In particular, by real-time detection of the power value, temperature value and irradiation intensity value of the sterilization lamp group, the key parameters of the sterilization process can be accurately obtained to ensure the effectiveness and safety of the sterilization process. Drawing a power change graph based on the real-time power value, drawing a temperature change graph based on the real-time temperature value, and drawing an intensity change graph based on the real-time irradiation intensity value can help to intuitively display the changing trend of parameters over time, which is convenient for analysis and judgment. By analyzing the power change graph, temperature change graph and intensity change graph, the power, temperature and intensity safety evaluation values ​​are determined, so as to quantitatively and accurately evaluate the safety performance of the lamp group. Analyzing the power change graph, temperature change graph and intensity change graph to determine the influence relationship between power, temperature and intensity helps to understand the interaction between parameters. Based on the influence relationship, the scoring weight values ​​corresponding to the power, temperature and intensity safety evaluation values ​​are respectively determined to more accurately evaluate the safety performance of the lamp group. Based on the power safety evaluation value, temperature safety evaluation value and intensity safety evaluation value and the scoring weight value, the safety performance of the lamp group is comprehensively evaluated to improve the effectiveness and safety of the sterilization process.

[0051] In particular, by calculating the Pearson correlation coefficient between any two of power, temperature and intensity, the linear relationship between them can be quantified, and their interaction in the sterilization process can be understood. Based on several correlation coefficients, the influence relationship between power, temperature and intensity can be determined, which is helpful to understand their interaction mechanism in the sterilization process. Based on the influence relationship, the scoring weight values ​​corresponding to the power, temperature and intensity safety evaluation values ​​are determined. The scoring weight values ​​reflect the contribution of each parameter to the safety of the sterilization process. Based on the power safety evaluation value, temperature safety evaluation value, intensity safety evaluation value and the scoring weight values, the safety performance of the sterilization lamp group is comprehensively evaluated to ensure the safety and effectiveness of the sterilization process. BRIEF DESCRIPTION OF THE DRAWINGS

[0052] Figure 1 A schematic diagram of a safety monitoring method based on radiation sterilization provided in an embodiment of the present invention;

[0053] Figure 2 A schematic diagram of the structure of the irradiation sterilization box provided in an embodiment of the present invention;

[0054] Figure 3 A schematic diagram of a process for determining an environmental safety evaluation value of a safety monitoring method based on radiation sterilization provided in an embodiment of the present invention;

[0055] Figure 4 A schematic diagram of a flow chart of adjusting preset working parameters of a safety monitoring method based on radiation sterilization provided in an embodiment of the present invention. DETAILED DESCRIPTION

[0056] In order to make the objects and advantages of the present invention more clearly understood, the present invention is further described below in conjunction with embodiments; it should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0057] The preferred embodiments of the present invention are described below with reference to the accompanying drawings. It should be understood by those skilled in the art that these embodiments are only used to explain the technical principles of the present invention and are not intended to limit the protection scope of the present invention.

[0058] It should be noted that, in the description of the present invention, terms such as "up", "down", "left", "right", "inside" and "outside" indicating directions or positional relationships are based on the directions or positional relationships shown in the drawings. This is merely for the convenience of description and does not indicate or imply that the device or element must have a specific orientation, be constructed and operated in a specific orientation. Therefore, it should not be understood as a limitation on the present invention.

[0059] In addition, it should be noted that in the description of the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected" and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, or it can be the internal communication of two components. For those skilled in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0060] See also Figure 1 As shown, an embodiment of the present invention provides a safety monitoring method based on radiation sterilization, the method comprising:

[0061] Step S100, placing the sample to be sterilized on the shelf in the sterilization box and closing the box door;

[0062] Step S200, detecting the actual airtightness between the box door and the box body, judging whether it is airtight according to the actual airtightness detection result, and determining to turn on the sterilization lamp group or adjust the actual airtightness between the box door and the box body according to the judgment result;

[0063] Step S300, the sterilization lamp group sterilizes the sample to be sterilized based on preset working parameters, detects the working parameters of the sterilization lamp group in real time, obtains the real-time working parameters, and determines the safety evaluation value of the lamp group based on the comparison result between the real-time working parameters and the preset working parameters;

[0064] Step S400 monitors the environmental parameters inside the box in real time during the sterilization process, obtains the real-time environmental parameters, and determines the environmental safety evaluation value based on the real-time environmental parameters and preset environmental parameters;

[0065] Step S500, adjusting the real-time working parameters of the sterilization lamp group based on the judgment result between the lamp group safety evaluation value and the preset lamp group evaluation value and / or the judgment result between the environmental safety evaluation value and the preset environmental safety evaluation value;

[0066] Step S600, sterilize the sample to be sterilized according to the adjusted sterilization lamp group, detect the sterilization effect of the sterilized sample to be verified after the sterilization is completed, and adjust the preset working parameters or complete the sterilization based on the comparison between the sterilization effect and the preset effect.

[0067] Specifically, the preset working parameters in the embodiment of the present invention are working parameters of the sterilization lamp group determined based on the characteristics of the sample to be sterilized.

[0068] Specifically, the embodiment of the present invention ensures that the sterilization box is completely sealed by detecting the actual airtightness between the box door and the box body, prevents radiation leakage, ensures the safety of the sterilization process, and improves the sterilization effect of the samples to be sterilized. It detects the working parameters of the sterilization lamp group in real time to provide an accurate data basis for the safety detection of the sterilization process and ensures the effectiveness of the sterilization process. It monitors the environmental parameters inside the box during the sterilization process in real time to ensure the safety of the sterilization process environment. Based on the real-time working parameters and environmental parameters, the safety of the lamp group and the environment is evaluated to comprehensively ensure the safety of the sterilization process and improve the effectiveness of the sterilization process. According to the safety evaluation value of the lamp group and the environmental safety evaluation value, the real-time working parameters of the sterilization lamp group are adjusted to optimize the sterilization process and ensure the safety of the sterilization process. After the sterilization is completed, the sterilization effect is detected on the sterilized samples to be verified. According to the detection results, the preset working parameters are adjusted or the sterilization is confirmed to be completed, thereby providing an accurate data basis for the next sterilization process and improving the safety of the next sterilization process.

[0069] See also Figure 2As shown, it is a schematic diagram of the structure of the radiation sterilization box according to an embodiment of the present invention, including a box body 1, a box door 2, a storage rack 3, a radiation lamp 4, an air density detector 5, a sample slot 6, a connecting rod 7, an observation chamber 8, an exhaust device 9, an air outlet 10, a lamp group temperature sensor 11, an ambient temperature sensor 12, a power sensor 13 and a light intensity sensor 14. The storage rack 3 is fixedly provided with a plurality of sample slots 6 for placing samples to be sterilized. The box body 1 is fixedly provided with an air density detector 5, an ambient temperature sensor 12 and an air density detector 5 for The air density value inside the box is detected in real time, and then the pressure value inside the box is obtained. The ambient temperature sensor 12 is used to detect the temperature value inside the box in real time. The radiation lamp 4 is hinged to one end of the connecting rod 7, and the other end of the connecting rod 7 is fixedly connected to the inside of the box 1. The lamp group temperature sensor 11 and the light intensity sensor 14 are respectively fixedly arranged on the outside of the radiation lamp 4 to detect the real-time temperature value and real-time irradiation intensity value of the lamp group of the radiation lamp 4. The power sensor 13 is fixed to the circuit of the radiation lamp 4. The cabinet 1 is connected to the cabinet 2 to detect the power value of the radiation lamp 4 in real time. An exhaust device 9 is provided under the shelf 3, and an air outlet 10 is provided under the box body 1 to discharge the residual radiation energy and heat in the sterilization box after the sterilization is completed. A transparent observation cabin 8 is provided on the cabinet door 2 to observe the sterilization process in real time. When the sample to be sterilized is subjected to radiation sterilization, the sample to be sterilized is placed in the sample slot 6 on the shelf 3 in the sterilization box, the box door 2 is closed, and the airtightness between the box door 2 and the box body 1 is detected based on the air density detector 5. When the airtightness is detected After meeting the requirements, turn on the radiation lamp 4, monitor the safety of the lamp group in real time based on the lamp group temperature sensor 11, power sensor 13 and light intensity sensor 14, monitor the environmental safety in real time through the ambient temperature sensor 12 and air density detector 5, adjust the real-time working parameters of the sterilization lamp group based on the detection results, sterilize the samples to be sterilized according to the adjusted sterilization lamp group, detect the sterilization effect of the sterilized samples to be verified after sterilization, and adjust the preset working parameters based on the comparison between the sterilization effect and the preset effect, or determine whether the sterilization is completed.

[0070] Specifically, the step of detecting the actual airtightness between the box door and the box body includes:

[0071] Monitor the internal pressure value of the box in real time, obtain the real-time pressure value, and draw a pressure change graph based on the real-time pressure value;

[0072] Obtaining a pressure change rate based on a pressure change graph, comparing the pressure change rate with a preset rate change range, and obtaining a rate comparison result;

[0073] The actual airtightness between the box door and the box body is determined based on the rate comparison result.

[0074] Specifically, the embodiment of the present invention monitors the pressure value inside the box in real time, including:

[0075] Assuming the pressure value monitored at the i-th moment is P1, and the pressure value monitored at the i+1-th moment is P2, the corresponding pressure change rate is V=(|P2-P1|) / (i+1-i)=|P2-P1|.

[0076] Specifically, the preset rate change range described in the embodiment of the present invention is [Pi, Pmax], wherein Pi is the average of several pressure change rates detected when the box door is sealed with the box body, and Pmax is the maximum value of several pressure change rates detected when the box door is sealed with the box body.

[0077] Specifically, the step of judging whether the seal is sealed according to the actual seal detection result in the embodiment of the present invention includes:

[0078] When the pressure change rate falls within the preset change rate range, the box door is sealed with the box body;

[0079] On the contrary, the box door and the box body are not airtight.

[0080] Specifically, the steps of determining to turn on the sterilization lamp group or to adjust the actual airtightness of the box door and the box body according to the judgment result in the embodiment of the present invention include:

[0081] When the box door and the box body are sealed, turning on the sterilization lamp group;

[0082] When the box door and the box body are not airtight, the box door and the box body are adjusted until the box door and the box body are airtight.

[0083] Specifically, the step of obtaining the pressure change rate based on the pressure change graph in the embodiment of the present invention includes:

[0084] Calculating the slope value at each point in the pressure variation graph;

[0085] The maximum slope value among the plurality of slope values ​​is selected as the pressure change rate.

[0086] Specifically, the embodiment of the present invention monitors the pressure value inside the box in real time and draws a pressure change graph, which intuitively shows the pressure change trend over time, helps to identify possible leakage points, obtains the pressure change rate based on the pressure change graph, and compares it with the preset rate change range, can further confirm whether the airtightness meets the requirements, and comprehensively judge the actual airtightness between the box door and the box body, ensuring that the sterilization box is completely sealed, which helps to improve the effectiveness of the sterilization process, while preventing radiation leakage and improving the safety of the sterilization process.

[0087] Specifically, the step of real-time detection of the working parameters of the sterilization lamp group includes:

[0088] Detecting the power value of the sterilization lamp group in real time based on a power sensor to obtain a real-time power value;

[0089] Based on the lamp group temperature sensor, the temperature value of the sterilization lamp group is detected in real time to obtain the real-time temperature value of the lamp group;

[0090] The light intensity sensor detects the irradiance intensity value of the sterilization lamp group in real time to obtain the real-time irradiance intensity value.

[0091] Specifically, the step of determining the safety evaluation value of the lamp group based on the comparison result of the real-time working parameter and the preset working parameter includes:

[0092] Draw a power change graph based on the real-time power value, analyze the power change graph, and determine a power safety evaluation value according to the analysis result of the power change graph;

[0093] Draw a temperature change graph based on the real-time temperature value of the lamp group, analyze the temperature change graph, and determine a temperature safety evaluation value according to the analysis result of the temperature change graph;

[0094] Draw an intensity change graph based on the real-time irradiation intensity value, analyze the intensity change graph, and determine the intensity safety evaluation value according to the analysis result of the intensity change graph;

[0095] Analyze the power change graph, the temperature change graph, and the strength change graph, determine the influence relationship among power, temperature, and strength according to the analysis results, and determine the scoring weight values ​​corresponding to the power safety evaluation value, the temperature safety evaluation value, and the strength safety evaluation value respectively based on the influence relationship;

[0096] The lamp group safety evaluation value is determined based on the power safety evaluation value, the temperature safety evaluation value, the intensity safety evaluation value and the scoring weight value.

[0097] Specifically, the step of drawing a power change graph based on the real-time power value in the embodiment of the present invention includes:

[0098] Establish a rectangular coordinate system with time as the horizontal axis and power value as the vertical axis;

[0099] A plurality of the real-time power values ​​are plotted in the rectangular coordinate system in the form of points, and two adjacent points are connected to obtain the power change graph.

[0100] Specifically, the embodiment of the present invention accurately obtains the key parameters in the sterilization process by real-time detection of the power value, temperature value and irradiation intensity value of the sterilization lamp group, ensures the effectiveness and safety of the sterilization process, draws a power change graph based on the real-time power value, draws a temperature change graph based on the real-time temperature value, and draws an intensity change graph based on the real-time irradiation intensity value, which helps to intuitively display the changing trend of the parameters over time, facilitates analysis and judgment, and determines the power, temperature and intensity safety evaluation values ​​by analyzing the power change graph, temperature change graph and intensity change graph, so as to quantitatively and accurately evaluate the safety performance of the lamp group, analyzes the power change graph, temperature change graph and intensity change graph, and determines the influence relationship between power, temperature and intensity, which helps to understand the interaction between parameters, and determines the scoring weight values ​​corresponding to the power, temperature and intensity safety evaluation values ​​based on the influence relationship, so as to more accurately evaluate the safety performance of the lamp group, and comprehensively evaluates the safety performance of the lamp group based on the power safety evaluation value, temperature safety evaluation value and intensity safety evaluation value as well as the scoring weight values, thereby improving the effectiveness and safety of the sterilization process.

[0101] Specifically, the step of determining the power safety evaluation value according to the analysis result of the power change diagram includes:

[0102] Identifying the fluctuation frequency and fluctuation amplitude in the power variation graph;

[0103] Calculating fluctuation stability based on a comparison result between the fluctuation frequency and a preset fluctuation frequency and a comparison result between the fluctuation amplitude and a preset fluctuation amplitude;

[0104] The power safety evaluation value is calculated based on the fluctuation stability.

[0105] Specifically, the method for obtaining the temperature safety evaluation value and the strength safety evaluation value in the embodiment of the present invention is the same as the method for obtaining the power safety evaluation value.

[0106] Specifically, the fluctuation amplitude in the embodiment of the present invention is obtained by subtracting the minimum value of the ordinate from the maximum value of the ordinate in the power variation diagram;

[0107] The fluctuation frequency is obtained by dividing the number of peak points in the power variation diagram by the number of total coordinate points.

[0108] Specifically, the preset fluctuation amplitude in the embodiment of the present invention is the average of several fluctuation amplitudes of the power variation diagram corresponding to the sterilization lamp group in the historical sterilization process;

[0109] The preset fluctuation frequency is the average of several fluctuation frequencies of the power variation diagram corresponding to the sterilization lamp group in the historical sterilization process.

[0110] Specifically, the step of calculating the fluctuation stability based on the comparison result between the fluctuation frequency and the preset fluctuation frequency and the comparison result between the fluctuation amplitude and the preset fluctuation amplitude in the embodiment of the present invention includes:

[0111] Calculating the difference between the fluctuation frequency and the preset fluctuation frequency, and dividing the difference by the preset fluctuation frequency to calculate a frequency stability value;

[0112] Calculating the difference between the fluctuation amplitude and the preset fluctuation amplitude, and dividing the difference by the preset fluctuation amplitude to calculate the amplitude stability value;

[0113] The frequency stability value and the amplitude stability value are added to obtain the fluctuation stability.

[0114] Specifically, the embodiment of the present invention intuitively clarifies the stability of the sterilization lamp group during operation by identifying the fluctuation frequency and fluctuation amplitude in the power change graph, calculates the fluctuation stability based on the comparison results of the fluctuation frequency with the preset fluctuation frequency and the comparison results of the fluctuation amplitude with the preset fluctuation amplitude, evaluates the stability of the operation of the sterilization lamp group, and calculates the power safety evaluation value based on the fluctuation stability to reflect the power safety of the sterilization lamp group. The method for obtaining the temperature safety evaluation value and the intensity safety evaluation value is the same as the method for obtaining the power safety evaluation value, ensuring the consistency of the evaluation methods of the three safety evaluation values. The fluctuation amplitude is obtained by calculating the maximum value of the ordinate in the power change graph minus the minimum value of the ordinate, the fluctuation frequency is obtained by calculating the number of peak points in the power change graph divided by the number of total coordinate points, and the fluctuation parameters are accurately obtained. The preset fluctuation amplitude and the preset fluctuation frequency are determined by the average of the fluctuation amplitude and the fluctuation frequency of the power change graph corresponding to the sterilization lamp group in the historical sterilization process to reflect the historical operation situation, and the fluctuation stability is obtained by calculating the frequency stability value and the amplitude stability value, and adding the two to obtain the fluctuation stability, and the power stability of the sterilization lamp group is comprehensively evaluated, thereby improving the safety of the operation process of the sterilization lamp group.

[0115] Specifically, the step of determining the influence relationship between power, temperature and intensity according to the analysis result includes:

[0116] Calculate the correlation coefficient between any two of the power, the temperature and the intensity based on the Pearson correlation coefficient;

[0117] An influence relationship among the power, the temperature and the intensity is determined based on a plurality of the correlation coefficients.

[0118] Specifically, the step of determining the scoring weight values ​​corresponding to the power safety evaluation value, the temperature safety evaluation value, and the strength safety evaluation value based on the influence relationship in the embodiment of the present invention includes:

[0119] The scoring weight value corresponding to the power safety evaluation value is the sum of the power factors between the power and the temperature and the intensity respectively divided by the sum of the total correlation coefficients;

[0120] The scoring weight value corresponding to the temperature safety evaluation value is the sum of the power factors between the temperature and the power and the intensity respectively divided by the sum of the total correlation coefficients;

[0121] The scoring weight value corresponding to the strength safety evaluation value is the sum of the power factors between the strength and the power and the temperature divided by the sum of the total correlation coefficients.

[0122] Specifically, the embodiment of the present invention calculates the Pearson correlation coefficient between any two of power, temperature and intensity, quantifies the linear relationship between them, understands their interaction in the sterilization process, and determines the influence relationship between power, temperature and intensity based on several correlation coefficients, which helps to understand their interaction mechanism in the sterilization process. Based on the influence relationship, the scoring weight values ​​corresponding to the power, temperature and intensity safety evaluation values ​​are determined. The scoring weight values ​​reflect the contribution of each parameter to the safety of the sterilization process. Based on the power safety evaluation value, the temperature safety evaluation value, the intensity safety evaluation value and the scoring weight values, the safety performance of the sterilization lamp group is comprehensively evaluated to ensure the safety and effectiveness of the sterilization process.

[0123] See also Figure 3 As shown, the step of determining the environmental safety evaluation value based on the real-time environmental parameters and the preset environmental parameters includes:

[0124] Step S410, real-time detection of the ambient temperature and air density inside the box during the sterilization process;

[0125] Step S420, calculating an ambient temperature evaluation value based on a comparison result between the ambient temperature value and a preset temperature value;

[0126] Step S430, calculating an air density evaluation value based on a comparison result between the air density value and a preset density value;

[0127] Step S440: Calculate the environmental safety evaluation value based on the environmental temperature evaluation value and the air density evaluation value.

[0128] Specifically, the preset temperature value in the embodiment of the present invention is the average value of the internal ambient temperature of the box during the historical sterilization process;

[0129] The preset density value is the average value of the air density inside the box during the historical sterilization process.

[0130] Specifically, the environmental temperature evaluation value in the embodiment of the present invention is obtained by dividing the difference between the environmental temperature value and the preset temperature value by the preset temperature value;

[0131] The air density evaluation value is obtained by dividing the difference between the air density value and the preset density value by the preset density value;

[0132] The environmental safety evaluation value is obtained by multiplying the environmental temperature evaluation value by the air density evaluation value.

[0133] Specifically, the embodiment of the present invention detects the ambient temperature value and air density value inside the box during the sterilization process in real time, understands the changes in environmental parameters in real time, and calculates the ambient temperature evaluation value based on the comparison result of the ambient temperature value and the preset temperature value to reflect the influence of the ambient temperature on the sterilization process. Based on the comparison result of the air density value and the preset density value, the air density evaluation value is calculated to reflect the influence of the air density on the sterilization process. Based on the ambient temperature evaluation value and the air density evaluation value, the environmental safety evaluation value is comprehensively evaluated to ensure that the environmental conditions of the sterilization process are suitable and the safety of the sterilization process environment is guaranteed.

[0134] Specifically, the step of adjusting the real-time working parameters of the sterilization lamp group based on the judgment result of the lamp group safety evaluation value and the preset lamp group evaluation value and / or the judgment result of the environmental safety evaluation value and the preset environmental safety evaluation value includes:

[0135] When the safety evaluation value of the lamp group is greater than the preset lamp group evaluation value, the sterilization lamp group is determined to be in an abnormal state, and the adjustment range is determined based on the ratio of the difference between the lamp group safety evaluation value and the preset lamp group evaluation value to the preset lamp group evaluation value, and the real-time working parameters of the sterilization lamp group are adjusted down based on the adjustment range, and the adjusted lamp group safety evaluation value is detected and calculated, and the operation stops when the lamp group safety evaluation value is less than or equal to the preset lamp group safety evaluation value;

[0136] When the environmental safety evaluation value is greater than the preset environmental evaluation value, it is determined that the sterilization lamp group is in an abnormal state. The difference between the environmental safety evaluation value and the preset environmental evaluation value and the ratio of the preset environmental evaluation value are used as the adjustment range. The real-time working parameters of the sterilization lamp group are reduced and adjusted based on the adjustment range. The adjusted environmental safety evaluation value is detected and calculated, and the operation stops when the environmental safety evaluation value is less than or equal to the preset environmental safety evaluation value.

[0137] Specifically, the embodiment of the present invention also includes not adjusting the sterilization lamp group when the lamp group safety evaluation value is less than or equal to the preset lamp group evaluation value and the environmental safety evaluation value is less than or equal to the preset environmental evaluation value.

[0138] Specifically, in the embodiment of the present invention, when the lamp group safety evaluation value is greater than the preset lamp group evaluation value or the environmental safety evaluation value is greater than the preset environmental evaluation value, it is determined that the sterilization lamp group is in an abnormal state, and the problem is discovered and handled in time to ensure the safety and effectiveness of the sterilization process.

[0139] See also Figure 4 As shown, the step of adjusting the preset working parameters based on the comparison between the sterilization effect and the preset effect includes:

[0140] Step S610, when the sterilization effect does not match the preset effect, determining the difference between the sterilization effect and the preset effect;

[0141] Step S620, when the sterilization effect is stronger than the preset effect, reducing the preset working parameters according to the difference;

[0142] Step S630: when the sterilization effect is lower than the preset effect, increase the preset working parameter according to the difference.

[0143] Specifically, the sterilization effect of the sterilized sample to be verified after the sterilization is completed as described in the embodiment of the present invention can be tested by a color-changing indicator.

[0144] Specifically, the preset effect in the embodiment of the present invention is set based on the sterilization requirements for the sample to be sterilized.

[0145] Specifically, the step of determining the difference between the sterilization effect and the preset effect according to the embodiment of the present invention includes:

[0146] When the sterilization effect of the sterilized sample to be verified is monitored by the color-changing indicator, determining the actual brightness value of the monitored display color;

[0147] The actual brightness value is compared with a preset brightness value corresponding to a preset effect, and the difference is determined based on the comparison result.

[0148] Specifically, the difference degree in the embodiment of the present invention may be the difference between the actual brightness value and the preset brightness value.

[0149] Specifically, the embodiment of the present invention evaluates whether the actual effect of the sterilization process reaches the expected goal by comparing the sterilization effect with the preset effect. When the sterilization effect does not match the preset effect, the gap between the actual effect and the expected goal is judged based on the difference, and the preset working parameters are adjusted to optimize the sterilization process.

[0150] Specifically, the step of reducing the preset working parameters according to the difference includes:

[0151] Dividing the difference by the standard value corresponding to the preset effect, and taking the result as the reduction amplitude;

[0152] The preset working parameters are adjusted based on the reduction range to obtain adjusted sterilization parameters.

[0153] Specifically, the adjusted sterilization parameter in the embodiment of the present invention = (1-reduction amplitude) × preset working parameter.

[0154] Specifically, the embodiment of the present invention obtains a reduction amplitude by dividing the difference by the standard value corresponding to the preset effect, which reflects the gap between the sterilization effect and the preset effect. The preset working parameters are adjusted based on the reduction amplitude to optimize the sterilization process and ensure that the sterilization effect reaches the expected goal. The formula for adjusting the sterilization parameters is (1-reduction amplitude) × preset working parameters, which ensures that the adjusted parameters are still within a reasonable range. At the same time, it reflects the impact of the difference on the preset parameters. By adjusting the preset working parameters, the sterilization process is continuously optimized, the sterilization effect is improved, and potential risks are reduced.

[0155] So far, the technical solutions of the present invention have been described in conjunction with the preferred embodiments shown in the accompanying drawings. However, it is easy for those skilled in the art to understand that the protection scope of the present invention is obviously not limited to these specific embodiments. Without departing from the principle of the present invention, those skilled in the art can make equivalent changes or substitutions to the relevant technical features, and the technical solutions after these changes or substitutions will fall within the protection scope of the present invention.

[0156] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. For those skilled in the art, the present invention may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A safety monitoring method based on irradiation sterilization, characterized in that: include: Place the samples to be sterilized on the shelf in the sterilization box and close the door; Detect the actual tightness between the box door and the box body, determine whether it is airtight according to the actual tightness test result, and determine to turn on the sterilization lamp group or adjust the actual tightness between the box door and the box body according to the judgment result; The sterilization lamp group sterilizes the sample to be sterilized based on preset working parameters, detects the working parameters of the sterilization lamp group in real time, obtains the real-time working parameters, and determines the safety evaluation value of the lamp group based on the comparison result between the real-time working parameters and the preset working parameters; Real-time monitoring of the environmental parameters inside the box during the sterilization process, obtaining the real-time environmental parameters, and determining the environmental safety evaluation value based on the real-time environmental parameters and preset environmental parameters; Adjusting the real-time working parameters of the sterilization lamp group based on the judgment result of the lamp group safety evaluation value and the preset lamp group evaluation value and / or the judgment result of the environmental safety evaluation value and the preset environmental safety evaluation value; The sample to be sterilized is sterilized according to the adjusted sterilization lamp group, the sterilization effect of the sterilized sample to be verified after the sterilization is completed is detected, and based on the comparison between the sterilization effect and the preset effect, it is determined whether the preset working parameters are adjusted or the sterilization is completed.

2. The safety monitoring method based on radiation sterilization according to claim 1, characterized in that: The step of detecting the actual airtightness between the box door and the box body comprises: Monitor the internal pressure value of the box in real time, obtain the real-time pressure value, and draw a pressure change graph based on the real-time pressure value; Obtaining a pressure change rate based on a pressure change graph, comparing the pressure change rate with a preset rate change range, and obtaining a rate comparison result; The actual airtightness between the box door and the box body is determined based on the rate comparison result.

3. The safety monitoring method based on radiation sterilization according to claim 2, characterized in that: The step of real-time detection of the working parameters of the sterilization lamp group comprises: Detecting the power value of the sterilization lamp group in real time based on a power sensor to obtain a real-time power value; Based on the lamp group temperature sensor, the temperature value of the sterilization lamp group is detected in real time to obtain the real-time temperature value of the lamp group; The light intensity sensor detects the irradiance intensity value of the sterilization lamp group in real time to obtain the real-time irradiance intensity value.

4. The safety monitoring method based on irradiation sterilization according to claim 3, characterized in that: The step of determining the safety evaluation value of the lamp group based on the comparison result of the real-time working parameter and the preset working parameter comprises: Draw a power change graph based on the real-time power value, analyze the power change graph, and determine a power safety evaluation value according to the analysis result of the power change graph; Draw a temperature change graph based on the real-time temperature value of the lamp group, analyze the temperature change graph, and determine a temperature safety evaluation value according to the analysis result of the temperature change graph; Draw an intensity change graph based on the real-time irradiation intensity value, analyze the intensity change graph, and determine the intensity safety evaluation value according to the analysis result of the intensity change graph; Analyze the power change graph, the temperature change graph, and the strength change graph, determine the influence relationship among power, temperature, and strength according to the analysis results, and determine the scoring weight values ​​corresponding to the power safety evaluation value, the temperature safety evaluation value, and the strength safety evaluation value respectively based on the influence relationship; The lamp group safety evaluation value is determined based on the power safety evaluation value, the temperature safety evaluation value, the intensity safety evaluation value and the scoring weight value.

5. The safety monitoring method based on radiation sterilization according to claim 4, characterized in that: The step of determining the power safety evaluation value according to the analysis result of the power variation diagram comprises: Identifying the fluctuation frequency and fluctuation amplitude in the power variation graph; Calculating fluctuation stability based on a comparison result between the fluctuation frequency and a preset fluctuation frequency and a comparison result between the fluctuation amplitude and a preset fluctuation amplitude; The power safety evaluation value is calculated based on the fluctuation stability.

6. The safety monitoring method based on radiation sterilization according to claim 5, characterized in that: The step of determining the influence relationship between power, temperature and intensity according to the analysis result comprises: Calculate the correlation coefficient between any two of the power, the temperature and the intensity based on the Pearson correlation coefficient; An influence relationship among the power, the temperature and the intensity is determined based on a plurality of the correlation coefficients.

7. The safety monitoring method based on radiation sterilization according to claim 6, characterized in that: The step of determining the environmental safety evaluation value based on the real-time environmental parameters and the preset environmental parameters includes: Real-time detection of the ambient temperature and air density inside the box during the sterilization process; Calculating an environmental temperature evaluation value based on a comparison result between the environmental temperature value and a preset temperature value; Calculating an air density evaluation value based on a comparison result between the air density value and a preset density value; The environmental safety evaluation value is calculated based on the environmental temperature evaluation value and the air density evaluation value.

8. The safety monitoring method based on irradiation sterilization according to claim 7, characterized in that: The step of adjusting the real-time working parameters of the sterilization lamp group based on the judgment result of the lamp group safety evaluation value and the preset lamp group evaluation value and / or the judgment result of the environmental safety evaluation value and the preset environmental safety evaluation value comprises: When the lamp group safety evaluation value is greater than the preset lamp group evaluation value and / or the environmental safety evaluation value is greater than the preset environmental evaluation value, it is determined that the sterilization lamp group is in an abnormal state, and the real-time working parameters of the sterilization lamp group are adjusted down until the lamp group safety evaluation value or the environmental safety evaluation value meets the requirements and stops.

9. The safety monitoring method based on radiation sterilization according to claim 8, characterized in that: The step of adjusting the preset working parameters based on the comparison between the sterilization effect and the preset effect comprises: When the sterilization effect does not match the preset effect, determining the difference based on the sterilization effect and the preset effect; When the sterilization effect is stronger than the preset effect, reducing the preset working parameter according to the difference; When the sterilization effect is lower than the preset effect, the preset working parameter is increased according to the difference.

10. The safety monitoring method based on radiation sterilization according to claim 9, characterized in that: The step of reducing the preset working parameters according to the difference comprises: Dividing the difference by the standard value corresponding to the preset effect, and taking the result as the reduction amplitude; The preset working parameters are adjusted based on the reduction range to obtain adjusted sterilization parameters.

Images