Foaming test device and system

Abstract

The invention discloses a foaming test device and system. According to the foaming test device, left / right atrial angiography tests can be taken into consideration at the same time, and when the foaming test device is switched into the left atrial angiography working mode, normal saline and a contrast agent can be automatically mixed to form a left atrial angiography mixed solution, and a left atrial angiography foaming solution is further formed; when the foaming test device is switched into a right atrial angiography working mode, normal saline, air and blood can be automatically mixed to form a right atrial angiography mixed solution, and a right atrial angiography foaming solution is further formed; the first injector and the second injector are matched with each other to perform reciprocating injection, so that the foaming efficiency of the left / right atrial angiography mixed liquid can be effectively improved, the time for forming the bubble liquid is shortened, automatic preparation of the left / right atrial angiography bubble liquid is quickly realized, meanwhile, the quality, preparation efficiency and consistency of the bubble liquid can be improved, and the production cost is reduced. And the accuracy of auxiliary screening is improved.

Description

Technical Field

[0001] The present application relates to the field of medical device technology, and in particular to a foaming test device and system. Background Art

[0002] Cardiac contrast echocardiography is divided into left atrial bubble test and right atrial bubble test. Among them, the indications of right atrial bubble test include: 1) screening for patent foramen ovale (PFO); 2) diagnosis of congenital vascular malformations, such as persistent left superior vena cava, pulmonary arteriovenous fistula, etc.; 3) evaluation of right heart cavity diameter, endocardial border contour, ventricular wall thickness, presence of mass and valvular regurgitation, etc.; 4) finding the cause for patients with hypoxemia. Therefore, right atrial bubble test can be used for auxiliary screening and detection of various diseases.

[0003] For the right atrium bubble test, it is necessary to extract physiological saline, purified air and patient blood separately to obtain a right atrium contrast mixture, then foam the right atrium contrast mixture to obtain a right atrium contrast bubble solution, and finally inject the right atrium contrast bubble solution into the human body for subsequent tests. The indications for the left atrium bubble test include: 1) coronary heart disease; 2) heart failure; 3) intracardiac masses; 4) auxiliary judgment of abnormal cardiac structure diseases such as hypertrophic cardiomyopathy. Therefore, the left atrium bubble test can also be used for auxiliary screening and detection of various diseases.

[0004] For the left atrium foaming test, it is necessary to extract physiological saline and mix it with powdered contrast agent to obtain a left atrium contrast mixture, then foam the left atrium contrast mixture to obtain a left atrium contrast foaming liquid, and finally inject the left atrium contrast foaming liquid into the human body for subsequent tests. At present, the preparation of the left atrium foaming liquid is carried out manually. The prepared left atrium foaming liquid has problems such as poor quality and consistency, and low preparation efficiency. Summary of the invention

[0005] The main purpose of the present application is to provide a foaming test device and system to solve the problem that the foaming test device in the prior art cannot take into account the automated preparation of both the left atrial contrast foaming solution and the right atrial contrast foaming solution.

[0006] According to one aspect of the present application, the present application provides a foaming test device, the foaming test device comprising:

[0007] A pipeline, comprising a first sub-pipeline and a second sub-pipeline, wherein the first sub-pipeline has a first end and a second end opposite to each other, and the second sub-pipeline has a third end and a fourth end opposite to each other, wherein the second end is connected to an externally connected indwelling needle, and the third end is connected to the first sub-pipeline, and one of the first end and the fourth end is connected to a first container, and the first container is used to contain a powdered contrast agent, and the other of the first end and the fourth end is connected to a second container, and the second container is used to contain physiological saline;

[0008] a first syringe and a second syringe, for performing a push injection and / or a withdrawal action, respectively;

[0009] A first valve, disposed on the first sub-pipeline, having at least three interfaces, two of which are used to communicate with the first sub-pipeline, and at least one other interface is used to communicate with the outside world;

[0010] A second valve, disposed on the first sub-pipeline, having at least three interfaces, two of which are used to connect to the first sub-pipeline, and at least one other interface is used to connect to the first syringe;

[0011] A third valve, disposed on the first sub-pipeline, having at least three interfaces, two of which are used to connect to the first sub-pipeline, and at least one other interface is used to connect to the second syringe;

[0012] a fourth valve, disposed on the first sub-pipeline, having at least three interfaces, two of which are used to communicate with the first sub-pipeline, and at least one other interface is used to communicate with the third end;

[0013] The foaming test device has a left atrium contrast working mode and a right atrium contrast working mode. In the left atrium contrast working mode, one of the first syringe and the second syringe transfers the physiological saline in the second container to the first container, so that the contrast agent is dissolved in the physiological saline in the first container to form a left atrium contrast mixed solution, and the first syringe and the second syringe reciprocally push the left atrium contrast mixed solution to form a left atrium contrast bubble solution.

[0014] In the right atrial contrast working mode, one of the first syringe and the second syringe first draws physiological saline from the second container, then draws air from the outside through the first valve, and draws blood through the indwelling needle to form a right atrial contrast mixture, and the first syringe and the second syringe reciprocally push the right atrial contrast mixture to form a right atrial contrast bubble solution.

[0015] According to another aspect of the present application, the present application further provides a foaming test system, the system comprising any one of the foaming test devices described above; and

[0016] A mixing device, the mixing device is used to drive the first container to move so that the contrast agent contained in the first container is fully dissolved in the physiological saline to form a uniform left atrial contrast mixture, and to make the left atrial contrast mixture foam; wherein the mixing device is integrated on the foaming test device, or the mixing device is independent of the foaming test device.

[0017] In the foaming test device of the present application, the preparation of left atrial foaming liquid can be carried out in a fully automatic manner, and the prepared left atrial foaming liquid has good quality, strong consistency and high preparation efficiency; in addition, the foaming test device can take into account both left atrial contrast test and right atrial contrast test, wherein, when left atrial contrast is required, the foaming test device is switched to the left atrial contrast working mode, and the foaming test device can control the first syringe or the second syringe to automatically extract the physiological saline in the second container and inject it into the first container, so that the contrast agent in the first container is dissolved into the physiological saline to form a left atrial contrast mixed liquid, and the left atrial contrast mixed liquid is reciprocally pushed by the first syringe and the second syringe to form a left atrial contrast foaming liquid, and finally the left atrial contrast foaming liquid is injected into the human body; when right atrial contrast is required, the foaming test device is switched to the left atrial contrast working mode. When the device is switched to the right atrial contrast working mode, the foaming test device can control the first syringe or the second syringe to automatically extract the physiological saline, purified air and blood in the second container in sequence to form a right atrial contrast mixture, and the first syringe and the second syringe are used to reciprocately push the right atrial contrast mixture to form a right atrial contrast foaming liquid, and finally the right atrial contrast foaming liquid is injected into the human body; and whether it is a left atrial contrast mixture or a right atrial contrast mixture, the first syringe and the second syringe cooperate with each other to perform reciprocating push injection, which can effectively improve the foaming efficiency of the left atrial contrast mixture and the right atrial contrast mixture, thereby shortening the time for forming the bubble liquid, quickly realizing the automatic preparation of the left atrial contrast bubble liquid or the right atrial contrast bubble liquid, and at the same time can also improve the quality, preparation efficiency and consistency of the bubble liquid, and improve the accuracy of auxiliary screening. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] The drawings described herein are used to provide a further understanding of the present application and constitute a part of the present application. The illustrative embodiments of the present application and their descriptions are used to explain the present application and do not constitute an improper limitation on the present application. In the drawings:

[0019] Figure 1 This is an overall schematic diagram of a system in an embodiment disclosed in the present application, showing that a shaking device is integrated into a foaming test device.

[0020] Figure 2 This is an overall schematic diagram of a system in an embodiment disclosed in the present application, which shows that the shaking device is independent of the foaming test device.

[0021] Figure 3 for Figure 1 A schematic diagram of the pipeline connection status in the disclosed embodiment shows that the first valve, the second valve, the third valve and the fourth valve are arranged in sequence from the first end to the second end of the first sub-pipeline, and the first end is connected to the second container, and the fourth end is connected to the first container.

[0022] Figure 4 for Figure 1 A schematic diagram of the pipeline connection status in the disclosed embodiment shows that the first valve, the second valve, the third valve and the fourth valve are arranged in sequence from the first end to the second end of the first sub-pipeline, and the first end is connected to the first container and the fourth end is connected to the second container.

[0023] Figure 5 This is a schematic diagram of the pipeline connection status in an embodiment disclosed in the present application, showing that the fourth valve, the first valve, the second valve and the third valve are arranged in sequence from the first end to the second end of the first sub-pipeline, and the first end is connected to the second container, and the fourth end is connected to the first container.

[0024] Figure 6 This is a schematic diagram of the pipeline connection status in an embodiment disclosed in the present application, showing that the fourth valve, the first valve, the second valve and the third valve are arranged in sequence from the first end to the second end of the first sub-pipeline, and the first end is connected to the first container, and the fourth end is connected to the second container.

[0025] Figure 7 This is an overall schematic diagram of a foaming test device in an embodiment disclosed in the present application, in which only the first valve, the second valve and the third valve are shown.

[0026] Figure 8 This is a partial structural schematic diagram of a foaming test device in an embodiment disclosed in the present application, in which only the first valve, the second valve and the third valve are shown.

[0027] Fig. 9 This is a schematic diagram of opening the dust cover of a foaming test device in an embodiment disclosed in the present application, in which only the first valve, the second valve and the third valve are shown.

[0028] Fig.10 This is another schematic diagram of a partial structure of a foaming test device in an embodiment disclosed in the present application, in which only the first valve, the second valve and the third valve are shown.

[0029] Fig.11This is a schematic diagram of the structure of a foaming test device in cooperation with an air blowing device in an embodiment disclosed in the present application, in which only the first valve, the second valve and the third valve are shown.

[0030] Fig.12 It is a three-dimensional schematic diagram of a shaking device in an embodiment disclosed in the present application.

[0031] Fig.13 It is a schematic diagram of an explosion of a shaking device in one embodiment disclosed in the present application.

[0032] Fig.14 -C is an overall schematic diagram of a shaking device in an embodiment disclosed in the present application, in which the receiving member is shown in a first position; Fig.14 -C1 is Fig.14 -C is a schematic cross-sectional view along the A-A1 direction.

[0033] Fig.15 -D is an overall schematic diagram of a shaking device in an embodiment disclosed in the present application, in which the receiving member is shown in the second position; Fig.15 -D1 is Fig.15 -D is a schematic cross-sectional view along the B-B1 direction. DETAILED DESCRIPTION

[0034] It should be noted that, in the absence of conflict, the embodiments and features in the embodiments of the present application can be combined with each other. The present application will be described in detail below with reference to the accompanying drawings and in combination with the embodiments.

[0035] See also Figure 1-3 As shown, the present application provides a foaming test device 100 , which includes a pipeline, a first valve 130 , a second valve 140 , a third valve 150 , a fourth valve 151 , a first syringe 160 and a second syringe 170 .

[0036] The pipeline includes a first sub-pipeline 123 and a second sub-pipeline 124. The first sub-pipeline 123 has a first end 121 and a second end 122 opposite to each other. The second sub-pipeline 124 has a third end 125 and a fourth end 126 opposite to each other. The second end 122 is connected to an externally connected indwelling needle, and the third end 125 is connected to the first sub-pipeline 123.

[0037] Furthermore, one of the first end 121 and the fourth end 126 is connected to the first container 101, and the first container 101 is used to contain powdered contrast agent; the other of the first end 121 and the fourth end 126 is connected to the second container 110, and the second container 110 is used to contain physiological saline. The first syringe 160 and the second syringe 170 are used to perform push injection and extraction operations respectively.

[0038] The first valve 130 is disposed on the first sub-pipeline 123 and has at least three interfaces, two of which are used to communicate with the first sub-pipeline 123 and at least one other interface is used to communicate with the outside.

[0039] The second valve 140 is disposed on the first sub-pipeline 123 , and the second valve 140 has at least three interfaces, two of which are used to connect to the first sub-pipeline 123 , and at least one other interface is used to connect to the first syringe 160 .

[0040] The third valve 150 is disposed on the first sub-pipeline 123 , and the third valve 150 has at least three interfaces, two of which are used to connect to the first sub-pipeline 123 , and at least one other interface is used to connect to the second syringe 170 .

[0041] The fourth valve 151 is arranged on the first sub-pipeline 123, and the fourth valve 151 has at least three interfaces, two of which are used to connect to the first sub-pipeline 123, and at least one other interface is used to connect to the third end 125, so that the first sub-pipeline 123 and the second sub-pipeline 124 are connected to each other through the fourth valve 151.

[0042] Furthermore, the foaming test device 100 has a left atrial contrast working mode and a right atrial contrast working mode. Therefore, the foaming test device 100 can take into account both the left atrial contrast test and the right atrial contrast test. Among them, the left atrial contrast working mode is used to dissolve the powdered contrast agent in saline to form a left atrial contrast foaming liquid, and further process the left atrial contrast mixed liquid to form a left atrial contrast foaming liquid. The right atrial contrast working mode is used to mix the saline, purified air and the patient's blood to form a right atrial contrast mixed liquid, and further process the right atrial contrast mixed liquid to form a right atrial contrast foaming liquid.

[0043] In the left atrium contrast working mode, one of the first syringe 160 and the second syringe 170 transfers the physiological saline in the second container 110 to the first container 101, so that the contrast agent is dissolved in the physiological saline in the first container 101 to form a left atrium contrast mixed solution, and the first syringe 160 and the second syringe 170 reciprocally push the left atrium contrast mixed solution to form a left atrium contrast bubble solution;

[0044] In the right atrial contrast working mode, one of the first syringe 160 and the second syringe 170 first draws physiological saline from the second container 110, then draws air from the outside through the first valve 130, and draws blood through the indwelling needle to form a right atrial contrast mixture. The first syringe 160 and the second syringe 170 reciprocally push the right atrial contrast mixture to form a right atrial contrast bubble solution.

[0045] Furthermore, whether it is the left atrial contrast mixture or the right atrial contrast mixture, the reciprocating injection by the first syringe 160 and the second syringe 170 can effectively improve the foaming efficiency of the left atrial contrast mixture or the right atrial contrast mixture, thereby shortening the time for forming the bubble liquid, and quickly realizing the automatic preparation of the left atrial contrast bubble liquid or the right atrial contrast bubble liquid, while also improving the quality, preparation efficiency and consistency of the bubble liquid, and improving the accuracy of auxiliary screening.

[0046] Furthermore, compared with setting up only one syringe to push and extract the left atrial contrast mixture or the right atrial contrast mixture, in this embodiment, the first syringe 160 and the second syringe 170 cooperate with each other to reciprocately push the left atrial contrast mixture or the right atrial contrast mixture, which can effectively reduce the resistance of the left atrial contrast mixture or the right atrial contrast mixture when it reciprocates between the first syringe 160 and the second syringe 170, thereby further improving the preparation efficiency of the left atrial contrast bubble solution or the right atrial contrast bubble solution.

[0047] Furthermore, after the preparation of the left atrial contrast foaming solution is completed, the foaming solution is injected into the patient's body from the patient's vein through an indwelling needle, and a left atrial foaming test is performed.

[0048] Preferably, the first syringe 160 and the second syringe 170 cooperate with each other to push and inject at least 20 times, so that the left atrial contrast mixture can form a left atrial contrast foaming solution with good consistency.

[0049] Furthermore, the left atrial contrast foaming solution may be injected into the patient's body from the patient's vein via the indwelling needle through the first syringe 160 , or may be injected into the patient's body from the patient's vein via the indwelling needle through the second syringe 170 .

[0050] Preferably, the left atrial contrast bubble solution is injected from the second syringe 170 into the patient's body from the patient's vein via the indwelling needle to shorten the journey of the left atrial contrast bubble solution before entering the patient's body.

[0051] For further information, see Figure 1-3 As shown, in the first embodiment, the first valve 130, the second valve 140, the third valve 150 and the fourth valve 151 are sequentially arranged on the first sub-pipeline 123 along the direction from the first end 121 to the second end 122, and the first end 121 is connected to the second container 110, and the fourth end 126 is connected to the first container 101.

[0052] In the left atrial angiography working mode, the foaming test device 100 has a plurality of switchable pipeline states.

[0053] When switched to the first pipeline state, the first valve 130 and the second valve 140 are respectively configured to connect the liquid path between the second container 110 and the first syringe 160, so as to control the first syringe 160 to extract physiological saline from the second container 110. At this time, the first valve 130 closes the interface connected to the outside, and the second valve 140 closes the first sub-pipeline 123 between the first syringe 160 and the third valve 150.

[0054] Alternatively, the first valve 130, the second valve 140 and the third valve 150 are respectively configured to connect the liquid path between the second container 110 and the second syringe 170 to control the second syringe 170 to extract physiological saline from the second container 110. At this time, the first valve 130 closes the interface connected to the outside, the second valve 140 closes the interface connected to the first syringe 160, and the third valve 150 closes the first sub-pipeline 123 between the second syringe 170 and the fourth valve 151.

[0055] When switched to the second pipeline state, the second valve 140, the third valve 150 and the fourth valve 151 are respectively configured to connect the liquid path between the first syringe 160 and the first container 101, so as to control the first syringe 160 to push the extracted physiological saline into the first container 101, so that the contrast agent contained in the first container 101 is mixed with the injected physiological saline to obtain a left atrium contrast mixed solution. At this time, the second valve 140 closes the first sub-pipeline 123 between the first syringe 160 and the first valve 130, and the fourth valve 151 closes the first sub-pipeline 123 between the first container 101 and the second end 122.

[0056] Alternatively, the third valve 150 and the fourth valve 151 are respectively configured to connect the liquid path between the second syringe 170 and the first container 101, so as to control the second syringe 170 to push the extracted physiological saline into the first container 101, so that the contrast agent contained in the first container 101 is mixed with the injected physiological saline to obtain a left atrium contrast mixed solution. At this time, the third valve 150 closes the first sub-pipeline 123 between the second syringe 170 and the second valve 140, and the fourth valve 151 closes the first sub-pipeline 123 between the first container 101 and the second end 122.

[0057] When switched to the third pipeline state, the second valve 140, the third valve 150 and the fourth valve 151 are respectively set to connect the liquid path between the first syringe 160 and the first container 101, so as to control the first syringe 160 to extract the left atrial contrast mixed solution from the first container 101. At this time, the second valve 140 closes the first sub-pipeline 123 between the first syringe 160 and the first valve 130, the third valve 150 closes the interface connected to the second syringe 170, and the fourth valve 151 closes the first sub-pipeline 123 between the first container 101 and the second end 122.

[0058] Alternatively, the third valve 150 and the fourth valve 151 are respectively configured to connect the liquid path between the second syringe 170 and the first container 101 to control the second syringe 170 to extract the left atrial contrast mixed solution from the first container 101. At this time, the third valve 150 closes the first sub-pipeline 123 between the second syringe 170 and the second valve 140, and the fourth valve 151 closes the first sub-pipeline 123 between the first container 101 and the second end 122.

[0059] When switched to the fourth pipeline state, the second valve 140 and the third valve 150 are configured to connect the liquid path between the first syringe 160 and the second syringe 170 to control the first syringe 160 and the second syringe 170 to reciprocate and push the left atrium contrast mixture. At this time, the second valve 140 closes the first sub-pipeline 123 between the first syringe 160 and the first valve 130, and the third valve 150 closes the first sub-pipeline 123 between the second syringe 170 and the fourth valve 151.

[0060] For further information, see Figure 1 , 2 4, in the second embodiment, the first valve 130, the second valve 140, the third valve 150 and the fourth valve 151 are sequentially arranged on the first sub-pipeline 123 from the first end 121 to the second end 122. However, the difference from the first embodiment is that the first end 121 is connected to the first container 101, and the fourth end 126 is connected to the second container 110.

[0061] In the left atrial angiography working mode corresponding to the present embodiment, the foaming test device 100 also has a plurality of switchable pipeline states.

[0062] When switched to the first pipeline state, the second valve 140, the third valve 150 and the fourth valve 151 are respectively configured to connect the liquid path between the second container 110 and the first syringe 160 to control the first syringe 160 to extract physiological saline from the second container 110. At this time, the second valve 140 closes the first sub-pipeline 123 between the first syringe 160 and the first valve 130, the third valve 150 closes the interface connected to the second syringe 170, and the fourth valve 151 closes the first sub-pipeline 123 between the second container 110 and the second end 122.

[0063] Alternatively, the third valve 150 and the fourth valve 151 are respectively configured to connect the liquid path between the second container 110 and the second syringe 170 to control the second syringe 170 to extract physiological saline from the second container 110. At this time, the third valve 150 closes the first sub-pipeline 123 between the second syringe 170 and the second valve 140, and the fourth valve 151 closes the first sub-pipeline 123 between the second syringe 170 and the second end 122.

[0064] When switched to the second pipeline state, the first valve 130 and the second valve 140 are respectively configured to connect the liquid path between the first syringe 160 and the first container 101, so as to control the first syringe 160 to push the extracted physiological saline into the first container 101, so that the contrast agent contained in the first container 101 is mixed with the injected physiological saline to obtain a left atrium contrast mixed solution. At this time, the first valve 130 closes the interface connected to the outside, and the second valve 140 closes the first sub-pipeline 123 between the first syringe 160 and the third valve 150.

[0065] Alternatively, the first valve 130, the second valve 140 and the third valve 150 are respectively configured to connect the liquid path between the second syringe 170 and the first container 101, so as to control the second syringe 170 to push the extracted physiological saline into the first container 101, so that the contrast agent contained in the first container 101 is mixed with the injected physiological saline to obtain a left atrium contrast mixed solution. At this time, the first valve 130 closes the interface connected to the outside, the second valve 140 closes the interface connected to the first syringe 160, and the third valve 150 closes the first sub-pipeline 123 between the second syringe 170 and the fourth valve 151.

[0066] When switched to the third pipeline state, the first valve 130 and the second valve 140 are respectively configured to connect the liquid path between the first syringe 160 and the first container 101, so as to control the first syringe 160 to extract the left atrial contrast mixed solution from the first container 101. At this time, the first valve 130 closes the interface connected to the outside, and the second valve 140 closes the first sub-pipeline 123 between the first syringe 160 and the third valve 150.

[0067] Alternatively, the first valve 130, the second valve 140 and the third valve 150 are respectively configured to connect the liquid path between the second syringe 170 and the first container 101, so as to control the second syringe 170 to extract the left atrial contrast mixed solution from the first container 101. At this time, the first valve 130 closes the interface connected to the outside, the second valve 140 closes the interface connected to the first syringe 160, and the third valve 150 closes the first sub-pipeline 123 between the second syringe 170 and the fourth valve 151.

[0068] When switched to the fourth pipeline state, the second valve 140 and the third valve 150 are configured to connect the liquid path between the first syringe 160 and the second syringe 170 to control the first syringe 160 and the second syringe 170 to reciprocate and push the left atrium contrast mixture. At this time, the second valve 140 closes the first sub-pipeline 123 between the first syringe 160 and the first valve 130, and the third valve 150 closes the first sub-pipeline 123 between the second syringe 170 and the fourth valve 151.

[0069] For further information, see Figure 1 , 2 As shown in Figure 5, in the third embodiment, the fourth valve 151, the first valve 130, the second valve 140 and the third valve 150 are sequentially arranged on the first sub-pipeline 123 along the direction from the first end 121 to the second end 122, and the first end 121 is connected to the second container 110, and the fourth end 126 is connected to the first container 101.

[0070] In the left atrial angiography working mode, the foaming test device 100 has a plurality of switchable pipeline states.

[0071] When switched to the fifth pipeline state, the fourth valve 151, the first valve 130 and the second valve 140 are respectively set to connect the liquid path between the second container 110 and the first syringe 160 to control the first syringe 160 to extract physiological saline from the second container 110. At this time, the fourth valve 151 closes the interface connected to the second sub-pipeline 124, the first valve 130 closes the interface connected to the outside, and the second valve 140 closes the first sub-pipeline 123 connected between the first syringe 160 and the third valve 150.

[0072] Alternatively, the fourth valve 151, the first valve 130, the second valve 140 and the third valve 150 are respectively configured to connect the liquid path between the second container 110 and the second syringe 170 to control the second syringe 170 to extract physiological saline from the second container 110. At this time, the fourth valve 151 closes the interface connected to the second sub-pipeline 124, the first valve 130 closes the interface connected to the outside, the second valve 140 closes the interface connected to the first syringe 160, and the third valve 150 closes the first sub-pipeline 123 between the second syringe 170 and the second end 122.

[0073] When switched to the sixth pipeline state, the fourth valve 151, the first valve 130 and the second valve 140 are respectively set to connect the liquid path between the first syringe 160 and the first container 101, so as to control the first syringe 160 to push the extracted physiological saline into the first container 101, so that the contrast agent contained in the first container 101 is mixed with the injected physiological saline to obtain a left atrium contrast mixed solution. At this time, the fourth valve 151 closes the interface connected to the second container 110, the first valve 130 closes the interface connected to the outside, and the second valve 140 closes the first sub-pipeline 123 connected between the first syringe 160 and the third valve 150.

[0074] Alternatively, the fourth valve 151, the first valve 130, the second valve 140 and the third valve 150 are respectively configured to connect the liquid path between the second syringe 170 and the first container 101, so as to control the second syringe 170 to push the extracted physiological saline into the first container 101, so that the contrast agent contained in the first container 101 is mixed with the injected physiological saline to obtain a left atrium contrast mixed solution. At this time, the fourth valve 151 closes the interface connected to the second container 110, the first valve 130 closes the interface connected to the outside, the second valve 140 closes the interface connected to the first syringe 160, and the third valve 150 closes the first sub-pipeline 123 between the second syringe 170 and the second end 122.

[0075] When switched to the seventh pipeline state, the fourth valve 151, the first valve 130 and the second valve 140 are respectively set to connect the liquid path between the first syringe 160 and the first container 101, so as to control the first syringe 160 to extract the left atrial contrast mixed solution from the first container 101. At this time, the fourth valve 151 closes the interface connected to the second container 110, the first valve 130 closes the interface connected to the outside, and the second valve 140 closes the first sub-pipeline 123 connected between the first syringe 160 and the third valve 150.

[0076] Alternatively, the fourth valve 151, the first valve 130, the second valve 140 and the third valve 150 are respectively configured to connect the liquid path between the second syringe 170 and the first container 101, so as to control the second syringe 170 to extract the left atrial contrast mixed solution from the first container 101. At this time, the fourth valve 151 closes the interface connected to the second container 110, the first valve 130 closes the interface connected to the outside, the second valve 140 closes the interface connected to the first syringe 160, and the third valve 150 closes the first sub-pipeline 123 between the second syringe 170 and the second end 122.

[0077] When switched to the eighth pipeline state, the second valve 140 and the third valve 150 are configured to connect the liquid path between the first syringe 160 and the second syringe 170 to control the first syringe 160 and the second syringe 170 to reciprocate and push the left atrium contrast mixture. At this time, the second valve 140 closes the first sub-pipeline 123 between the first syringe 160 and the first valve 130, and the third valve 150 closes the first sub-pipeline 123 between the second syringe 170 and the second end 122.

[0078] For further information, see Figure 1 , 2 6, in the fourth embodiment, the fourth valve 151, the first valve 130, the second valve 140 and the third valve 150 are sequentially arranged on the first sub-pipeline 123 from the first end 121 to the second end 122. However, the difference from the third embodiment is that the first end 121 is connected to the first container 101, and the fourth end 126 is connected to the second container 110.

[0079] In the left atrial angiography working mode corresponding to the present embodiment, the foaming test device 100 also has a plurality of switchable pipeline states.

[0080] When switched to the fifth pipeline state, the fourth valve 151, the first valve 130 and the second valve 140 are respectively set to connect the liquid path between the second container 110 and the first syringe 160 to control the first syringe 160 to extract physiological saline from the second container 110. At this time, the fourth valve 151 closes the interface connected to the first container 101, the first valve 130 closes the interface connected to the outside, and the second valve 140 closes the first sub-pipeline 123 connected between the first syringe 160 and the third valve 150.

[0081] Alternatively, the fourth valve 151, the first valve 130, the second valve 140 and the third valve 150 are respectively configured to connect the liquid path between the second container 110 and the second syringe 170 to control the second syringe 170 to extract physiological saline from the second container 110. At this time, the fourth valve 151 closes the interface connected to the first container 101, the first valve 130 closes the interface connected to the outside, the second valve 140 closes the interface connected to the first syringe 160, and the third valve 150 closes the first sub-pipeline 123 between the second syringe 170 and the second end 122.

[0082] When switched to the sixth pipeline state, the fourth valve 151, the first valve 130 and the second valve 140 are respectively set to connect the liquid path between the first syringe 160 and the first container 101, so as to control the first syringe 160 to push the extracted physiological saline into the first container 101, so that the contrast agent contained in the first container 101 is mixed with the injected physiological saline to obtain a left atrium contrast mixed solution. At this time, the fourth valve 151 closes the interface connected to the second container 110, the first valve 130 closes the interface connected to the outside, and the second valve 140 closes the first sub-pipeline 123 connected between the first syringe 160 and the third valve 150.

[0083] Alternatively, the fourth valve 151, the first valve 130, the second valve 140 and the third valve 150 are respectively configured to connect the liquid path between the second syringe 170 and the first container 101, so as to control the second syringe 170 to push the extracted physiological saline into the first container 101, so that the contrast agent contained in the first container 101 is mixed with the injected physiological saline to obtain a left atrium contrast mixed solution. At this time, the fourth valve 151 closes the interface connected to the second container 110, the first valve 130 closes the interface connected to the outside, the second valve 140 closes the interface connected to the first syringe 160, and the third valve 150 closes the first sub-pipeline 123 between the second syringe 170 and the second end 122.

[0084] When switched to the seventh pipeline state, the fourth valve 151, the first valve 130 and the second valve 140 are respectively set to connect the liquid path between the first syringe 160 and the first container 101, so as to control the first syringe 160 to extract the left atrial contrast mixed solution from the first container 101. At this time, the fourth valve 151 closes the interface connected to the second container 110, the first valve 130 closes the interface connected to the outside, and the second valve 140 closes the first sub-pipeline 123 connected between the first syringe 160 and the third valve 150.

[0085] Alternatively, the fourth valve 151, the first valve 130, the second valve 140 and the third valve 150 are respectively configured to connect the liquid path between the second syringe 170 and the first container 101, so as to control the second syringe 170 to extract the left atrial contrast mixed solution from the first container 101. At this time, the fourth valve 151 closes the interface connected to the second container 110, the first valve 130 closes the interface connected to the outside, the second valve 140 closes the interface connected to the first syringe 160, and the third valve 150 closes the first sub-pipeline 123 between the second syringe 170 and the second end 122.

[0086] When switched to the eighth pipeline state, the second valve 140 and the third valve 150 are configured to connect the liquid path between the first syringe 160 and the second syringe 170 to control the first syringe 160 and the second syringe 170 to reciprocate and push the left atrium contrast mixture. At this time, the second valve 140 closes the first sub-pipeline 123 between the first syringe 160 and the first valve 130, and the third valve 150 closes the first sub-pipeline 123 between the second syringe 170 and the second end 122.

[0087] In some embodiments, the fourth valve 151 may also be disposed on the first sub-pipeline 123 and connected between the second valve 140 and the third valve 150 , which will not be described in detail herein.

[0088] For further information, see Figure 1-2 As shown, the foaming test device 100 further includes a hanger 280 . The second container 110 is disposed on the hanger 280 .

[0089] For further information, see Figure 7-8 As shown, the foaming test device 100 further includes a first valve 130 driving member 410, a second valve 140 driving member 410 and a third valve 150 driving member 410. The first valve 130 driving member 410, the second valve 140 driving member 410 and the third valve 150 driving member 410 are all motors. The first valve 130 driving member 410 is connected to the first valve 130 for switching the working state of the first valve 130. The second valve 140 driving member 410 is connected to the second valve 140 for switching the working state of the second valve 140. The third valve 150 driving member 410 is connected to the third valve 150 for switching the working state of the third valve 150. The first valve 130 driving member 410, the second valve 140 driving member 410 and the third valve 150 driving member 410 are all electrically connected to a control system, and the control system is used to control the working modes of the first valve 130 driving member 410, the second valve 140 driving member 410 and the third valve 150 driving member 410.

[0090] Furthermore, in the right atrial angiography working mode, the foaming test device 100 has a variety of different implementations. Figure 1-3 As shown, in the first embodiment, the first valve 130, the second valve 140, the third valve 150 and the fourth valve 151 are sequentially arranged on the first sub-pipeline 123 along the direction from the first end 121 to the second end 122, and the first end 121 is connected to the second container 110, and the fourth end 126 is connected to the first container 101.

[0091] In the right atrial angiography working mode, the foaming test device 100 has a plurality of switchable pipeline modes.

[0092] When switched to the first pipeline mode, the first valve 130 and the second valve 140 are configured to connect the liquid path between the second container 110 and the first syringe 160, so as to control the first syringe 160 to extract physiological saline from the second container 110. At this time, the first valve 130 closes the interface connected to the outside, and the second valve 140 closes the interface connected to the first syringe 160 and the third valve 150.

[0093] When switched to the second pipeline mode, the first valve 130, the second valve 140 and the third valve 150 are configured to connect the liquid path between the second container 110 and the second syringe 170 to control the second syringe 170 to extract physiological saline from the second container 110. At this time, the first valve 130 closes the interface connected to the outside, the second valve 140 closes the interface connected to the first syringe 160, and the third valve 150 closes the first sub-pipeline 123 connected between the second syringe 170 and the fourth valve 151.

[0094] When switched to the third pipeline mode, the first valve 130, the second valve 140 and the third valve 150 are configured to connect the liquid path between the outside and the second syringe 170 to control the second syringe 170 to extract air from the outside. At this time, the first valve 130 closes the interface connected to the second container 110, the second valve 140 closes the interface connected to the first syringe 160, and the third valve 150 closes the first sub-pipeline 123 between the second syringe 170 and the fourth valve 151.

[0095] When switched to the fourth pipeline mode, the third valve 150 and the fourth valve 151 are set to connect the liquid path between the second syringe 170 and the external indwelling needle. At this time, the third valve 150 closes the first sub-pipeline 123 between the second syringe 170 and the second valve 140, and the fourth valve 151 closes the interface connected to the second sub-pipeline 124. The second syringe 170 is controlled to discharge physiological saline from the indwelling needle, or the second syringe 170 is controlled to draw blood from the human body through the indwelling needle to form a right atrial contrast mixture, or the second syringe 170 is controlled to inject physiological saline or foaming liquid into the human body.

[0096] When switched to the fifth pipeline mode, the second valve 140, the third valve 150 and the fourth valve 151 are set to connect the liquid path between the first syringe 160 and the external indwelling needle. At this time, the second valve 140 closes the first sub-pipeline 123 between the first syringe 160 and the first valve 130, the third valve 150 closes the interface connected to the second syringe 170, and the fourth valve 151 closes the interface connected to the second sub-pipeline 124. The first syringe 160 is controlled to discharge the physiological saline from the indwelling needle, or the first syringe 160 is controlled to inject the physiological saline into the human body.

[0097] When switched to the sixth pipeline mode, the second valve 140 and the third valve 150 are configured to connect the liquid path between the first syringe 160 and the second syringe 170 to control the first syringe 160 and the second syringe 170 to reciprocate and push the right atrium contrast mixture. At this time, the second valve 140 closes the first sub-pipeline 123 connecting the first syringe 160 and the first valve 130, and the third valve 150 closes the first sub-pipeline 123 connecting the second syringe 170 and the fourth valve 151.

[0098] For further information, see Figure 1 , 2 As shown in FIG. 4 , in the second embodiment, the first valve 130, the second valve 140, the third valve 150 and the fourth valve 151 are sequentially arranged on the first sub-pipeline 123 along the direction from the first end 121 to the second end 122. The difference from the first embodiment is that the first end 121 is connected to the first container 101, and the fourth end 126 is connected to the second container 110.

[0099] In the right atrial angiography working mode of this embodiment, the foaming test device 100 has a plurality of switchable pipeline modes.

[0100] When switched to the first pipeline mode, the second valve 140, the third valve 150 and the fourth valve 151 are configured to connect the liquid path between the second container 110 and the first syringe 160, so as to control the first syringe 160 to extract physiological saline from the second container 110. At this time, the second valve 140 closes the first sub-pipeline 123 connecting the first syringe 160 and the first valve 130, the third valve 150 closes the interface connecting the second syringe 170, and the fourth valve 151 closes the first sub-pipeline 123 connecting the second container 110 and the second end 122.

[0101] When switched to the second pipeline mode, the third valve 150 and the fourth valve 151 are configured to connect the liquid path between the second container 110 and the second syringe 170 to control the second syringe 170 to extract physiological saline from the second container 110. At this time, the third valve 150 closes the first sub-pipeline 123 connecting the second syringe 170 and the second valve 140, and the fourth valve 151 closes the first sub-pipeline 123 connecting the second container 110 and the second end 122.

[0102] When switched to the third pipeline mode, the first valve 130, the second valve 140 and the third valve 150 are configured to connect the liquid path between the outside and the second syringe 170 to control the second syringe 170 to extract air from the outside. At this time, the first valve 130 closes the interface connected to the first container 101, the second valve 140 closes the interface connected to the first syringe 160, and the third valve 150 closes the first sub-pipeline 123 between the second syringe 170 and the fourth valve 151.

[0103] When switched to the fourth pipeline mode, the third valve 150 and the fourth valve 151 are set to connect the liquid path between the second syringe 170 and the external indwelling needle. At this time, the third valve 150 closes the first sub-pipeline 123 between the second syringe 170 and the second valve 140, and the fourth valve 151 closes the interface connected to the second sub-pipeline 124. The second syringe 170 is controlled to discharge physiological saline from the indwelling needle, or the second syringe 170 is controlled to draw blood from the human body through the indwelling needle to form a right atrial contrast mixture, or the second syringe 170 is controlled to inject physiological saline or foaming liquid into the human body.

[0104] When switched to the fifth pipeline mode, the second valve 140, the third valve 150 and the fourth valve 151 are set to connect the liquid path between the first syringe 160 and the external indwelling needle. At this time, the second valve 140 closes the first sub-pipeline 123 between the first syringe 160 and the first valve 130, the third valve 150 closes the interface connected to the second syringe 170, and the fourth valve 151 closes the interface connected to the second sub-pipeline 124. The first syringe 160 is controlled to discharge the physiological saline from the indwelling needle, or the first syringe 160 is controlled to inject the physiological saline into the human body.

[0105] When switched to the sixth pipeline mode, the second valve 140 and the third valve 150 are configured to connect the liquid path between the first syringe 160 and the second syringe 170 to control the first syringe 160 and the second syringe 170 to reciprocate and push the right atrium contrast mixture. At this time, the second valve 140 closes the first sub-pipeline 123 connecting the first syringe 160 and the first valve 130, and the third valve 150 closes the first sub-pipeline 123 connecting the second syringe 170 and the fourth valve 151.

[0106] For further information, see Figure 1 , 2 As shown in Figure 5, in the third embodiment, the fourth valve 151, the first valve 130, the second valve 140 and the third valve 150 are sequentially arranged on the first sub-pipeline 123 along the direction from the first end 121 to the second end 122, and the first end 121 is connected to the second container 110, and the fourth end 126 is connected to the first container 101.

[0107] In the right atrial angiography working mode, the foaming test device 100 has a plurality of switchable pipeline modes;

[0108] When switched to the seventh pipeline mode, the fourth valve 151, the first valve 130 and the second valve 140 are configured to connect the liquid path between the second container 110 and the first syringe 160, so as to control the first syringe 160 to extract physiological saline from the second container 110. At this time, the fourth valve 151 closes the interface connected to the second sub-pipeline 124, the first valve 130 closes the interface connected to the outside, and the second valve 140 closes the first sub-pipeline 123 connected between the first syringe 160 and the third valve 150.

[0109] When switched to the eighth pipeline mode, the fourth valve 151, the first valve 130, the second valve 140 and the third valve 150 are configured to connect the liquid path between the second container 110 and the second syringe 170, so as to control the second syringe 170 to extract physiological saline from the second container 110. At this time, the fourth valve 151 closes the interface connected to the second sub-pipeline 124, the first valve 130 closes the interface connected to the outside, the second valve 140 closes the interface connected to the first syringe 160, and the third valve 150 closes the first sub-pipeline 123 connected between the second syringe 170 and the second end 122.

[0110] When switched to the ninth pipeline mode, the first valve 130, the second valve 140 and the third valve 150 are configured to connect the liquid path between the outside and the second syringe 170 to control the second syringe 170 to extract air from the outside. At this time, the first valve 130 closes the interface connected to the fourth valve 151, the second valve 140 closes the interface connected to the first syringe 160, and the third valve 150 closes the first sub-pipeline 123 connected between the second syringe 170 and the second end 122.

[0111] When switched to the tenth pipeline mode, the third valve 150 is configured to connect the liquid path between the second syringe 170 and the external indwelling needle, so as to control the second syringe 170 to discharge physiological saline from the indwelling needle, or to control the second syringe 170 to draw blood from the human body through the indwelling needle to form a right atrial contrast mixture, or to control the second syringe 170 to inject physiological saline or foaming solution into the human body. At this time, the third valve 150 closes the first sub-pipeline 123 connecting the second syringe 170 and the second valve 140.

[0112] When switched to the eleventh pipeline mode, the second valve 140 and the third valve 150 are configured to connect the liquid path between the first syringe 160 and the external indwelling needle, so as to control the first syringe 160 to discharge the physiological saline from the indwelling needle, or to control the first syringe 160 to inject the physiological saline into the human body. At this time, the second valve 140 closes the first sub-pipeline 123 between the first syringe 160 and the first valve 130, and the third valve 150 closes the interface connected to the second syringe 170.

[0113] When switched to the twelfth pipeline mode, the second valve 140 and the third valve 150 are configured to connect the liquid path between the first syringe 160 and the second syringe 170 to control the first syringe 160 and the second syringe 170 to reciprocate and push the right atrium contrast mixture. At this time, the second valve 140 closes the first sub-pipeline 123 connecting the first syringe 160 and the first valve 130, and the third valve 150 closes the first sub-pipeline 123 connecting the second syringe 170 and the second end 122.

[0114] For further information, see Figure 1 , 2 6, in the fourth embodiment, the fourth valve 151, the first valve 130, the second valve 140 and the third valve 150 are sequentially arranged on the first sub-pipeline 123 along the direction from the first end 121 to the second end 122. Compared with the third embodiment described above, the difference of this embodiment is that the first end 121 is connected to the first container 101, and the fourth end 126 is connected to the second container 110.

[0115] In the right atrial angiography working mode of this embodiment, the foaming test device 100 has a plurality of switchable pipeline modes. Specifically, when switched to the seventh pipeline mode, the fourth valve 151, the first valve 130 and the second valve 140 are configured to connect the liquid path between the second container 110 and the first syringe 160 to control the first syringe 160 to extract physiological saline from the second container 110. At this time, the fourth valve 151 closes the interface connected to the first container 101, the first valve 130 closes the interface connected to the outside, and the second valve 140 closes the first sub-pipeline 123 connected between the first syringe 160 and the third valve 150.

[0116] When switched to the eighth pipeline mode, the fourth valve 151, the first valve 130, the second valve 140 and the third valve 150 are configured to connect the liquid path between the second container 110 and the second syringe 170, so as to control the second syringe 170 to extract physiological saline from the second container 110. At this time, the fourth valve 151 closes the interface connected to the first container 101, the first valve 130 closes the interface connected to the outside, the second valve 140 closes the interface connected to the first syringe 160, and the third valve 150 closes the first sub-pipeline 123 connected between the second syringe 170 and the second end 122.

[0117] When switched to the ninth pipeline mode, the first valve 130, the second valve 140 and the third valve 150 are configured to connect the liquid path between the outside and the second syringe 170 to control the second syringe 170 to extract air from the outside. At this time, the first valve 130 closes the interface connected to the fourth valve 151, the second valve 140 closes the interface connected to the first syringe 160, and the third valve 150 closes the first sub-pipeline 123 connected between the second syringe 170 and the second end 122.

[0118] When switched to the tenth pipeline mode, the third valve 150 is configured to connect the liquid path between the second syringe 170 and the external indwelling needle, so as to control the second syringe 170 to discharge physiological saline from the indwelling needle, or to control the second syringe 170 to draw blood from the human body through the indwelling needle to form a right atrial contrast mixture, or to control the second syringe 170 to inject physiological saline or foaming solution into the human body. At this time, the third valve 150 closes the first sub-pipeline 123 connecting the second syringe 170 and the second valve 140.

[0119] When switched to the eleventh pipeline mode, the second valve 140 and the third valve 150 are configured to connect the liquid path between the first syringe 160 and the external indwelling needle, so as to control the first syringe 160 to discharge the physiological saline from the indwelling needle, or to control the first syringe 160 to inject the physiological saline into the human body. At this time, the second valve 140 closes the first sub-pipeline 123 between the first syringe 160 and the first valve 130, and the third valve 150 closes the interface connected to the second syringe 170.

[0120] When switched to the twelfth pipeline mode, the second valve 140 and the third valve 150 are configured to connect the liquid path between the first syringe 160 and the second syringe 170 to control the first syringe 160 and the second syringe 170 to reciprocate and push the right atrium contrast mixture. At this time, the second valve 140 closes the first sub-pipeline 123 connecting the first syringe 160 and the first valve 130, and the third valve 150 closes the first sub-pipeline 123 connecting the second syringe 170 and the second end 122.

[0121] In some embodiments, the fourth valve 151 may also be disposed on the first sub-pipeline 123 and connected between the second valve 140 and the third valve 150 , which will not be described in detail herein.

[0122] Furthermore, in the foaming test device 100 of the present invention, one of the first end 121 and the fourth end 126 is connected to the first container 101 through management, and the other of the first end 121 and the fourth end 126 is connected to the second container 110. Therefore, the entire foaming test device 100 is automated, so the foaming test device 100 realizes the automatic extraction of physiological saline, external air, blood, left atrial contrast mixture and right atrial contrast mixture.

[0123] In some embodiments, the second container 110, the first valve 130, the first syringe 160, and the second syringe 170 are arranged in sequence along the direction from the first end 121 to the second end 122 of the pipeline, and the second syringe 170 is used to inject the obtained foaming liquid (microbubble embolic contrast agent) into the human body. On the basis that the foaming test device 100 can automatically extract physiological saline, after the second syringe 170 extracts blood, the first syringe 160 can push the extracted physiological saline into the human body to clean the pipeline and prevent blood from clotting in the pipeline and blocking the pipeline.

[0124] In addition, after the foaming liquid in the second syringe 170 is injected into the human body, the second syringe 170 and the first syringe 160 sequentially inject physiological saline into the human body, which can push the microbubble contrast agent into the human body as much as possible and can also clean the pipeline. If the foaming test fails this time, it will not affect the next foaming test.

[0125] In one embodiment, see Figure 7-11 In the present invention, the first sub-pipeline 123 is arranged along a straight line, and the first syringe 160 and the second syringe 170 are arranged side by side, so that the foaming test device 100 can be miniaturized as much as possible for easy use.

[0126] Furthermore, the foaming test device 100 of the present invention includes a first syringe driver 180 and a second syringe driver 190. The first syringe driver 180 includes a first syringe driver 180 body and a first syringe driver output 181 connected, the first syringe driver output 181 is connected to the piston of the first syringe 160, and the first syringe driver 180 body can drive the first syringe driver output 181 to move, so as to drive the piston of the first syringe 160 to move.

[0127] The second syringe driver 190 includes a connected second syringe 170 body and a second syringe driver output end 191, and the second syringe driver output end 191 is connected to the piston of the second syringe 170. The second syringe driver 190 body can drive the second syringe driver output end 191 to move, so as to drive the piston of the second syringe 170 to move.

[0128] Specifically, the first syringe driver 180 and the second syringe driver 190 are both lead screw modules. Position sensors are correspondingly provided at the first syringe driver output end 181 and the second syringe driver output end 191 to sense the movement position of the first syringe driver output end 181 and the second syringe driver output end 191 to prevent over-movement and safety problems.

[0129] In one embodiment, the foaming test device 100 further includes an air filter 200. The air filter 200 is connected to one of the interfaces of the first valve 130, and is used to purify the air entering from the outside to ensure that the foaming test is performed more safely.

[0130] For further information, see Figure 7-11 As shown, the foaming test device 100 further includes a first ultrasonic bubble sensor 210. The first ultrasonic bubble sensor 210 is correspondingly disposed between the second container 110 and the first valve 130 on the pipeline, and is used to monitor whether there are bubbles when the physiological saline passes through, so as to confirm whether the pipeline is leaking.

[0131] Specifically, when the first syringe 160 and the second syringe 170 extract saline, under normal circumstances, what is extracted is saline. When an abnormal situation occurs, such as poor sealing of the joint and leakage, some air may be extracted. When air passes through the pipe corresponding to the first ultrasonic bubble sensor 210, the first ultrasonic bubble sensor 210 outputs a high level. When the pipe contains saline, it outputs a low level. The control system determines whether the passing is air bubbles through the high and low level signals. When there are bubbles, the system will alarm and stop the next operation, thereby ensuring that the foaming test device 100 can extract saline.

[0132] See also Figure 7 As shown, the foaming test device 100 also includes a second ultrasonic bubble sensor 220. The second ultrasonic bubble sensor 220 is correspondingly arranged between the second syringe 170 and the indwelling needle on the pipeline, and is used to monitor whether there is air or large bubbles passing through during the foaming liquid injection process or the normal saline injection process to ensure injection safety.

[0133] Specifically, when the foaming liquid is injected into the human body, the foaming liquid will flow through the pipeline position corresponding to the second ultrasonic bubble sensor 220. At this time, if air or large bubbles pass through, the second ultrasonic bubble sensor 220 will sense it and output a low-level signal to the control system, and the control system will alarm and take corresponding measures to ensure that the foaming liquid injected into the human vein is safe and reliable. In the present invention, the first ultrasonic bubble sensor 210 and the second ultrasonic bubble sensor 220 can also be replaced with other types of sensors such as vision and blood oxygen.

[0134] See also Figure 8As shown, the foaming test device 100 also includes a blood oxygen detection sensor 230, which is correspondingly arranged between the second syringe 170 and the indwelling needle on the pipeline, and is used to monitor whether the blood passes within the specified time when drawing blood, so as to ensure the safety of the blood drawing process, and prevent the second syringe 170 from forming a negative pressure in the second syringe 170 due to failure to draw blood, thereby causing damage to the equipment and the human body. In the present invention, the blood oxygen detection sensor 230 can also be replaced with other types of sensors such as infrared sensing and vision.

[0135] See also Figure 8 As shown, the foaming test device 100 may further include a micro camera 240. The micro camera 240 is disposed corresponding to the second syringe 170 and is used to take an image of the foaming liquid to confirm the blood content in the foaming liquid and the number and size of microbubbles.

[0136] Specifically, the micro camera 240 sends the captured image to the control system. On the one hand, the control system determines whether the second syringe 170 has drawn enough blood by the color and liquid level of the foaming liquid in the second syringe 170. If no blood is drawn, the liquid in the second syringe 170 is a mixture of physiological saline and air, and the color is colorless, that is, the micro camera 240 is used to confirm whether the second syringe 170 has drawn blood. When no blood is drawn or the amount of blood is insufficient, the number of microbubble emboli in the foaming liquid will be very small, and it is easy to break, resulting in large bubbles, which is not conducive to detection.

[0137] On the other hand, the control system calculates the number and size of the microbubble emboli in the second syringe 170 shown in the picture (it should be noted that a large number of large pictures need to be given to the control system in the early stage for training, and the control system continues to learn, and finally the number and size of the microbubbles can be fed back based on the pictures sent by the micro camera 240), so as to provide a reference for the final inspection result. If the number of microbubble emboli is too small, the final inspection result may be inaccurate. If the microbubble emboli are too large, the final inspection result may also be inaccurate.

[0138] See also Fig.10 As shown, the device 100 also includes a thrust sensor. The thrust sensor includes at least a first thrust sensor 250 and a second thrust sensor 260. The first thrust sensor 250 is arranged corresponding to the output end 181 of the first syringe driver. When the foaming liquid is mixed or the first syringe 160 injects the physiological saline into the human body, the first thrust sensor 250 is used to sense the injection thrust of the output end 181 of the first syringe driver to ensure injection safety.

[0139] The second thrust sensor 260 is arranged corresponding to the second syringe driver output end 191. When the foaming liquid is mixed or the second syringe 170 injects saline into the human body, the second thrust sensor 260 is used to sense the injection thrust of the second syringe driver output end 191 to ensure injection safety.

[0140] Specifically, during injection, the indwelling needle may collide with the patient's blood vessel wall, causing the indwelling needle port to be blocked or the needle to slip. At this time, the injection will cause the push pressure to rise sharply. If the injection continues in this situation, it may cause damage to the patient's blood vessel wall or bulge in the elbow vein. Therefore, when the thrust sensor detects that the injection thrust exceeds a certain range and continues to rise, the system alarms and stops the injection to avoid harming the patient. The position of the indwelling needle needs to be adjusted manually later.

[0141] See also Figure 8-9 As shown, the foaming test device 100 of the present invention further includes a dust cover device 270. The dust cover device 270 includes a dust cover and a dust cover driving member 410. The dust cover driving member 410 is connected to the dust cover and is used to drive the dust cover to cover the parts where the air filter 200, the first syringe 160, the second syringe 170, the first valve 130, the second valve 140 and the third valve 150 are located. In addition, the foaming test device 100 has a boss, a valve motor is installed at the lower end of the boss, and the first syringe 160, the second syringe 170, the air filter 200, the first valve 130, the second valve 140, the third valve 150 and part of the pipeline are installed at the upper end, which saves space, facilitates the installation and operation of the dust cover, and is conducive to the miniaturization of the foaming test device 100.

[0142] A variety of monitoring devices are provided in the foaming test device 100 of the present invention to maximize the safety of the foaming test. Doctors do not need to pay attention to the operation of the equipment all the time and can use it with confidence. At the same time, the operating burden of doctors is also reduced. There is no need to manually draw physiological saline, air and blood. The foaming test device 100 is highly automated and operates safely and efficiently.

[0143] Furthermore, in the right atrial angiography mode, the working principle of the foaming test device 100 is as follows:

[0144] Preparation steps: first, the foaming test device 100 is switched to the first pipeline mode, and the first syringe 160 draws physiological saline from the container 110; then, the foaming test device 100 is switched to the second pipeline mode, and the second syringe 170 draws physiological saline from the container 110; the foaming test device 100 is then switched to the fourth pipeline mode, and the second syringe 170 discharges the physiological saline from the indwelling needle; finally, the foaming test device 100 is switched to the fifth pipeline mode, and the first syringe 160 discharges the physiological saline from the indwelling needle; wherein, when the first syringe 160 and the second syringe 170 discharge the physiological saline from the indwelling needle, both the first syringe 160 and the second syringe 170 should be pushed to the bottom to exhaust the air in the first syringe 160 and the second syringe 170.

[0145] In the preparation step, when the first syringe 160 and the second syringe 170 extract physiological saline, the first ultrasonic bubble sensor 210 monitors whether there are bubbles when the physiological saline passes through. If there are bubbles, an alarm is issued and the pipeline is checked for leaks.

[0146] Mixed liquid extraction steps: In the first step, the foaming test device 100 is switched to the first pipeline mode, and the first syringe 160 extracts physiological saline from the container 110; in the second step, the foaming test device 100 is switched to the second pipeline mode, and the second syringe 170 extracts physiological saline from the container 110; in the third step, the foaming test device 100 is switched to the third pipeline mode, and the second syringe 170 extracts air from the outside; in the fourth step, the foaming test device 100 is switched to the fourth pipeline mode, and the second syringe 170 extracts blood from the human body through the indwelling needle to obtain a mixed liquid. In this step, the blood oxygen detection sensor 2 30 monitors whether blood passes within the specified time, if not, alarms; fifth step, the foaming test device 100 switches to the fifth pipeline mode, the first syringe 160 injects saline into the human body, in this step, the second ultrasonic bubble sensor 220 monitors whether there are large bubbles or air when the foaming liquid passes, if so, the system alarms, and the equipment is adjusted later to ensure the safety of the foaming liquid injected into the human vein; at the same time, the first thrust sensor 250 senses the thrust of the output end 181 of the first syringe drive component, if the thrust continues to rise within a certain range, an alarm is sounded, and the indwelling needle is manually adjusted later. In addition, in the first and second steps, when the first syringe 160 and the second syringe 170 extract saline, the first ultrasonic bubble sensor 210 monitors whether there are bubbles when the saline passes, if there are bubbles, an alarm is sounded, and the pipeline is checked and leaked.

[0147] Foaming liquid preparation steps: the foaming test device 100 is switched to the sixth pipeline mode, the first syringe 160 and the second syringe 170 push the mixed liquid back and forth, the sum of the number of pushes by the first syringe 160 and the second syringe 170 is an even number (the purpose is to ensure that the foaming liquid is injected into the human body through the second syringe 170), and at least 20 times to obtain the foaming liquid.

[0148] In this step, the micro camera 240 captures an image of the foaming liquid in the second syringe 170 and sends the image to the control system to confirm whether the blood content in the foaming liquid meets the standard and the number and size of the microbubble emboli, so as to provide a reference for whether the subsequent foaming test results are accurate.

[0149] The first foaming liquid injection step: After obtaining the foaming liquid, the foaming test device 100 switches to the fourth pipeline mode, and the second syringe 170 injects the foaming liquid into the human body. When the foaming liquid is injected into the human body, the second thrust sensor 260 senses the injection thrust of the second syringe 170 (more specifically, senses the thrust of the output end 191 of the second syringe drive). If the injection thrust continues to rise, the system alarms and stops the injection. The position of the indwelling needle is subsequently adjusted before continuing the test. The second ultrasonic sensor monitors whether there are large bubbles when the foaming liquid passes by. If so, the control system alarms, and the foaming test device 100 is checked before conducting the test to ensure that the foaming liquid injected into the human vein is safe and reliable.

[0150] The first tube sealing step: After the first foaming liquid injection step, the foaming test device 100 is first switched to the second pipeline mode, and the second syringe 170 draws physiological saline from the container 110; then the foaming test device 100 is switched to the first pipeline mode, and the first syringe 160 draws physiological saline from the container 110; the foaming test device 100 is then switched to the fourth pipeline mode, and the second syringe 170 injects physiological saline into the human body; finally, the foaming test device 100 is switched to the fifth pipeline mode, and the first syringe 160 injects physiological saline into the human body, thereby completing the foaming test of the control group.

[0151] In this step, when the first syringe 160 and the second syringe 170 extract saline solution, the first ultrasonic bubble sensor 210 monitors whether there are bubbles when the saline solution flows through, and alarms if there are bubbles. The pipeline is then checked and repaired for leaks. At the same time, when the first syringe 160 and the second syringe 170 inject saline solution into the human body, the first thrust sensor 250 senses the thrust of the output end 181 of the first syringe drive component, and the second thrust sensor 260 senses the thrust of the output end 191 of the second syringe drive component. If the thrust sensed by one of the thrust sensors exceeds a certain range and continues to rise, the system alarms.

[0152] The second foaming liquid injection step: repeat the aforementioned mixed liquid extraction step and foaming liquid preparation step. After obtaining the foaming liquid, the patient blows air or performs a Eustachian tube inflation check. When the blowing or Eustachian tube inflation check action meets the standard, the foaming test device 100 switches to the fourth pipeline mode, and the second syringe 170 injects the foaming liquid into the human body.

[0153] Second tube sealing step: Repeat the first tube sealing step to complete the foaming test of the test group.

[0154] Before the first tube sealing step and the second tube sealing step, there is residual foaming liquid in the first sub-pipeline 123 between the second syringe 170 and the indwelling needle that has not been injected into the human body. The tube sealing step can push the foaming liquid remaining in the pipeline into the human body as much as possible, thereby ensuring that the foaming liquid is injected in sufficient amount as much as possible and cleaning the pipeline.

[0155] The foaming test device 100 of the present invention does not require manual extraction of saline, air and blood, nor does it require manual injection of foaming. Medical personnel only need to install the injection consumables on the foaming test device 100, and the foaming test device 100 can automatically complete the extraction, foaming, injection and emptying operations, saving labor costs and truly realizing that one person can complete the foaming test. Fig.12 The foaming test device 100 can also cooperate with the blowing device 300 to detect the real-time air pressure value through the pressure sensor in the blowing device 300, replacing the Valsalva action, which is simple to operate and has high accuracy.

[0156] On the other hand, see Figure 1-2 As shown, the present application also provides a foaming test system, which includes the above-mentioned foaming test device 100. Therefore, the system has all the beneficial effects of the above-mentioned foaming test device 100, which will not be repeated here.

[0157] The system also includes a mixing device 400. The mixing device 400 is used to drive the first container 101 to move so that the contrast agent contained in the first container 101 is fully dissolved in the physiological saline to form a uniform left atrial contrast mixture, and to make the left atrial contrast mixture foam. Specifically, the mixing device 400 is used to drive the first container 101 to move after the first syringe 160 or the second syringe 170 injects the physiological saline into the first container 101, so that the contrast agent in the first container 101 can be quickly and fully dissolved in the physiological saline to form a left atrial contrast mixture, and further shake the left atrial contrast mixture so that the left atrial contrast mixture can be mixed evenly and generate a large number of high-quality and stable microbubbles.

[0158] For further information, see Figure 1As shown, in one embodiment, the mixing device 400 is integrated on the foaming test device 100, so that the foaming test device 100 and the mixing device 400 are integrated to facilitate carrying the mixing device 400 and the foaming test device 100.

[0159] See also Figure 2 As shown, in another embodiment, the mixing device 400 is independent of the foaming test device 100, that is, the mixing device 400 is not integrated on the foaming test device 100, thereby making the system more flexible, so that medical personnel do not need to carry the mixing device 400 when performing the right atrial angiography working mode, or can carry the mixing device 400 for use with different foaming test devices 100.

[0160] For further information, see Figure 12-13 As shown, in one embodiment, the mixing device 400 includes a driving member 410 and a receiving member 420. The receiving member 420 is connected to the output shaft 412 of the driving member 410.

[0161] Among them, the receiving member 420 is structured to form a receiving groove 421, and the receiving groove 421 is used to receive the first container 101. Under the drive of the driving member 410, the receiving member 420 drives the first container 101 to reciprocate along the axial direction of the output shaft 412 to achieve mixing of the left atrial contrast mixture, or reciprocates circumferentially along the output shaft 412 to achieve mixing of the left atrial contrast mixture. It can also simultaneously drive the first container 101 to reciprocate along the axial direction of the output shaft 412 and reciprocate circumferentially along the output shaft 412, so that the left atrial contrast mixture shakes more violently in the first container 101, thereby having a better mixing effect.

[0162] Furthermore, the mixing device 400 further includes a fixing assembly 430 and a roller 440. The fixing assembly 430 is used to install and fix the driving member 410, so that the driving member 410 is fixed on the foaming test device 100, or a designated position outside the foaming test device 100.

[0163] The roller 440 is rotatably disposed on one of the fixed component 430 and the receiving component 420 and faces the other one of the fixed component 430 and the receiving component 420. The other corresponding roller 440 of the fixed component 430 and the receiving component 420 is provided with a groove 422. Under the forward and reverse reciprocating drive of the driving component 410, the roller 440 changes its position on the groove wall of the groove 422 to make the receiving component 420 reciprocate along the axial direction of the output shaft 412 and reciprocate along the circumferential direction of the output shaft 412. Thereby, the first container 101 contained in the receiving component 420 can keep a substantially synchronous movement with the receiving component 420.

[0164] Furthermore, the driving member 410 includes a driving body 411 and an output shaft 412. The driving body 411 is used to drive the output shaft 412 to rotate forward and reverse, thereby driving the receiving member 420 to rotate forward and reverse with the output shaft 412 as the rotation center, thereby driving the first container 101 to move synchronously.

[0165] Furthermore, the fixing assembly 430 includes a bracket 431 and a fixing member 432. The driving body 411 is fixedly connected to the bracket 431 and the fixing member 432 through a locking member, and the output shaft 412 passes through the bracket 431 and the fixing member 432 in sequence and extends out of the fixing member 432 to connect with the receiving member 420. The bracket 431 is used to fix the mixing device 400.

[0166] Specifically, the bracket 431 includes a connecting plate portion 4311 and mounting plate portions 4312 disposed on opposite sides of the connecting plate portion 4311. The connecting plate portion 4311 and the two mounting plate portions 4312 are configured to form a receiving groove 4313, and the driving body 411 is disposed in the receiving groove 4313. The fixing member 432 is disposed on a side of the connecting plate portion 4311 away from the receiving groove 4313, and the locking member sequentially passes through the fixing member 432 and the connecting plate portion 4311 and is locked into the driving body 411 to fix the driving member 410, the bracket 431 and the fixing member 432 together, and the output shaft 412 sequentially passes through the connecting plate portion 4311 and the fixing member 432 to be connected to the receiving member 420.

[0167] The two mounting plate portions 4312 are used to fix the mixing device 400 on the foaming test device 100 so that the mixing device 400 is integrated on the foaming test device 100 ; or the two mounting plate portions 4312 are used to fix the mixing device 400 at a designated position outside the foaming test device 100 .

[0168] Furthermore, the two rollers 440 are rotatably disposed on one side of the fixing member 432 facing the receiving member 420 via a rotating shaft 450 . The receiving member 420 is structured to form a groove 422 , and the groove 422 is disposed away from the receiving groove 421 .

[0169] See also Fig.14 As shown in FIG. 14-C, 14-C1, 15-D and 15-D1, the receiving member 420 has a first position and a second position relative to the driving member 410 along the axial direction of the output shaft 412, and the receiving member 420 reciprocates between the first position and the second position under the drive of the driving member 410.

[0170] When the receiving member 420 is in the first position, the two rollers 440 are respectively located at the lowest point of the groove 422, and the receiving member 420 is close to the fixing assembly 430. When the receiving member 420 is in the second position, the two rollers 440 are respectively located at the highest point of the groove 422, and the receiving member 420 is far away from the fixing assembly 430.

[0171] By arranging the two rollers 440 to move in the groove 422 , the receiving member 420 can reciprocate along the circumferential direction of the output shaft 412 when rotating with the output shaft 412 as the rotation center.

[0172] Furthermore, the driving member 410 drives the receiving member 420 to rotate forward and reversely at an angle less than or equal to 360 degrees, thereby effectively preventing the second sub-pipeline 124 connected to the first container 101 from being entangled.

[0173] Preferably, the driving member 410 drives the receiving member 420 to switch the rotation direction after each 180-degree rotation along the output shaft 412. That is, after each 180-degree clockwise rotation of the receiving member 420 by the driving member 410, the receiving member 420 is immediately driven to rotate 180-degree counterclockwise, and this is repeated for multiple times until the left atrium contrast mixed solution is fully mixed and a large number of microbubbles are generated.

[0174] For further information, see Fig.12 , 13 , 14-C1 and 15-D1, the mixing device 400 further includes a flexible member 460, which is disposed on the groove wall of the receiving groove 421, and is used to protect the first container 101 and / or limit the first container 101 in the receiving groove 421. Preferably, the flexible member 460 is a silicone sleeve, which is attached to the groove wall of the receiving groove 421, and is used to protect the first container 101, so as to prevent the first container 101 from rigidly colliding with the groove wall of the receiving groove 421 during the movement of the receiving member 420.

[0175] The above are only preferred embodiments of the present application and are not intended to limit the present application. For those skilled in the art, the present application may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims

1. A foaming test device, characterized in that: include: A pipeline, comprising a first sub-pipeline and a second sub-pipeline, wherein the first sub-pipeline has a first end and a second end opposite to each other, and the second sub-pipeline has a third end and a fourth end opposite to each other, wherein the second end is connected to an externally connected indwelling needle, and the third end is connected to the first sub-pipeline, and one of the first end and the fourth end is connected to a first container, and the first container is used to contain a powdered contrast agent, and the other of the first end and the fourth end is connected to a second container, and the second container is used to contain physiological saline; a first syringe and a second syringe, for performing a push injection and / or a withdrawal action, respectively; A first valve, disposed on the first sub-pipeline, having at least three interfaces, two of which are used to communicate with the first sub-pipeline, and at least one other interface is used to communicate with the outside world; A second valve, disposed on the first sub-pipeline, having at least three interfaces, two of which are used to connect to the first sub-pipeline, and at least one other interface is used to connect to the first syringe; A third valve, disposed on the first sub-pipeline, having at least three interfaces, two of which are used to connect to the first sub-pipeline, and at least one other interface is used to connect to the second syringe; a fourth valve, disposed on the first sub-pipeline, having at least three interfaces, two of which are used to communicate with the first sub-pipeline, and at least one other interface is used to communicate with the third end; The foaming test device has a left atrium contrast working mode and a right atrium contrast working mode. In the left atrium contrast working mode, one of the first syringe and the second syringe transfers the physiological saline in the second container to the first container, so that the contrast agent is dissolved in the physiological saline in the first container to form a left atrium contrast mixed solution, and the first syringe and the second syringe reciprocally push the left atrium contrast mixed solution to form a left atrium contrast bubble solution. In the right atrial contrast working mode, one of the first syringe and the second syringe first draws physiological saline from the second container, then draws air from the outside through the first valve, and draws blood through the indwelling needle to form a right atrial contrast mixture, and the first syringe and the second syringe reciprocally push the right atrial contrast mixture to form a right atrial contrast bubble solution.

2. The foaming test device according to claim 1, characterized in that: The first valve, the second valve, the third valve and the fourth valve are sequentially arranged on the first sub-pipeline along the direction from the first end to the second end, and the first end is connected to the second container, and the fourth end is connected to the first container; In the left atrial angiography working mode, the foaming test device has a plurality of switchable pipeline states; When switched to the first pipeline state, the first valve and the second valve are respectively configured to connect the liquid path between the second container and the first syringe, so as to control the first syringe to extract physiological saline from the second container; Alternatively, the first valve, the second valve and the third valve are respectively arranged to connect the liquid path between the second container and the second syringe to control the second syringe to extract physiological saline from the second container; When switched to the second pipeline state, the second valve, the third valve and the fourth valve are respectively arranged to connect the liquid path between the first syringe and the first container, so as to control the first syringe to push the extracted physiological saline into the first container, so that the contrast agent contained in the first container is mixed with the injected physiological saline to obtain the left atrium contrast mixed solution; Alternatively, the third valve and the fourth valve are respectively arranged to connect the liquid path between the second syringe and the first container, so as to control the second syringe to push the extracted physiological saline into the first container, so that the contrast agent contained in the first container is mixed with the injected physiological saline to obtain the left atrial contrast mixed solution; When switched to the third pipeline state, the second valve, the third valve and the fourth valve are respectively configured to connect the liquid path between the first syringe and the first container, so as to control the first syringe to extract the left atrial contrast mixed solution from the first container; Alternatively, the third valve and the fourth valve are respectively configured to connect the liquid path between the second syringe and the first container, so as to control the second syringe to extract the left atrial contrast mixed solution from the first container; When switched to the fourth pipeline state, the second valve and the third valve are configured to connect the liquid path between the first syringe and the second syringe to control the first syringe and the second syringe to reciprocately push the left atrial contrast mixture.

3. The foaming test device according to claim 1, characterized in that: The fourth valve, the first valve, the second valve and the third valve are sequentially arranged on the first sub-pipeline from the first end to the second end, and the first end is connected to the second container, and the fourth end is connected to the first container; In the left atrial angiography working mode, the foaming test device has a plurality of switchable pipeline states; When switched to the fifth pipeline state, the fourth valve, the first valve and the second valve are respectively configured to connect the liquid path between the second container and the first syringe to control the first syringe to extract physiological saline from the second container; Alternatively, the fourth valve, the first valve, the second valve and the third valve are respectively arranged to connect the liquid path between the second container and the second syringe to control the second syringe to extract physiological saline from the second container; When switched to the sixth pipeline state, the fourth valve, the first valve and the second valve are respectively configured to connect the liquid path between the first syringe and the first container, so as to control the first syringe to push the extracted physiological saline into the first container, so that the contrast agent contained in the first container is mixed with the injected physiological saline to obtain the left atrium contrast mixed solution; Alternatively, the fourth valve, the first valve, the second valve and the third valve are respectively arranged to connect the liquid path between the second syringe and the first container, so as to control the second syringe to push the extracted physiological saline into the first container, so that the contrast agent contained in the first container is mixed with the injected physiological saline to obtain the left atrial contrast mixed solution; When switched to the seventh pipeline state, the fourth valve, the first valve and the second valve are respectively configured to connect the liquid path between the first syringe and the first container, so as to control the first syringe to extract the left atrial contrast mixed solution from the first container; Alternatively, the fourth valve, the first valve, the second valve and the third valve are respectively arranged to connect the liquid path between the second syringe and the first container, so as to control the second syringe to extract the left atrial contrast mixed solution from the first container; When switched to the eighth pipeline state, the second valve and the third valve are configured to connect the liquid path between the first syringe and the second syringe to control the first syringe and the second syringe to reciprocately push the left atrial contrast mixture.

4. The foaming test device according to claim 1, characterized in that: The first valve, the second valve, the third valve and the fourth valve are sequentially arranged on the first sub-pipeline along the direction from the first end to the second end, and the first end is connected to the second container; In the right atrial angiography working mode, the foaming test device has a plurality of switchable pipeline modes; When switched to the first pipeline mode, the first valve and the second valve are configured to connect the liquid path between the second container and the first syringe to control the first syringe to extract physiological saline from the second container; When switched to the second pipeline mode, the first valve, the second valve and the third valve are configured to connect the liquid path between the second container and the second syringe to control the second syringe to extract physiological saline from the second container; When switched to the third pipeline mode, the first valve, the second valve and the third valve are configured to connect the liquid path between the outside and the second syringe to control the second syringe to extract air from the outside; When switched to the fourth pipeline mode, the third valve and the fourth valve are configured to connect the liquid path between the second syringe and the externally connected indwelling needle, so as to control the second syringe to discharge physiological saline from the indwelling needle, or to control the second syringe to draw blood from the human body through the indwelling needle to form a right atrial contrast mixture, or to control the second syringe to inject physiological saline or foaming solution into the human body; When switched to the fifth pipeline mode, the second valve, the third valve and the fourth valve are configured to connect the first syringe to the external indwelling needle to discharge the physiological saline from the indwelling needle, or to control the first syringe to inject the physiological saline into the human body; When switched to the sixth pipeline mode, the second valve and the third valve are configured to connect the liquid path between the first syringe and the second syringe to control the first syringe and the second syringe to reciprocately push the right atrial contrast mixture.

5. The foaming test device according to claim 1, characterized in that: The fourth valve, the first valve, the second valve and the third valve are sequentially arranged on the first sub-pipeline along the direction from the first end to the second end, and the first end is connected to the second container; In the right atrial angiography working mode, the foaming test device has a plurality of switchable pipeline modes; When switched to the seventh pipeline mode, the fourth valve, the first valve and the second valve are configured to connect the liquid path between the second container and the first syringe to control the first syringe to extract physiological saline from the second container; When switched to the eighth pipeline mode, the fourth valve, the first valve, the second valve and the third valve are configured to connect the liquid path between the second container and the second syringe to control the second syringe to extract physiological saline from the second container; When switched to the ninth pipeline mode, the first valve, the second valve and the third valve are configured to connect the liquid path between the outside and the second syringe, so as to control the second syringe to extract air from the outside; When switched to the tenth pipeline mode, the third valve is configured to connect the liquid path between the second syringe and the externally connected indwelling needle, so as to control the second syringe to discharge physiological saline from the indwelling needle, or to control the second syringe to draw blood from the human body through the indwelling needle to form a right atrial contrast mixture, or to control the second syringe to inject physiological saline or foaming solution into the human body; When switched to the eleventh pipeline mode, the second valve and the third valve are configured to connect the first syringe to the external indwelling needle to control the first syringe to discharge the physiological saline from the indwelling needle, or to control the first syringe to inject the physiological saline into the human body; When switched to the twelfth pipeline mode, the second valve and the third valve are configured to connect the liquid path between the first syringe and the second syringe to control the first syringe and the second syringe to reciprocately push the right atrial contrast mixture.

6. The foaming test device according to any one of claims 1 to 5, characterized in that: The foaming test device further comprises a blood oxygen detection sensor, which is disposed on the first sub-pipeline at a position corresponding to the second syringe and the external indwelling needle, and is used to monitor whether blood passes through within a specified time when blood is drawn, so as to ensure that the blood drawing process is carried out safely; and / or The foaming test device further comprises an air filter, which is connected to an interface of the first valve connected to the outside world and is used to purify air entering from the outside world; and / or The foaming test device further comprises a first ultrasonic bubble sensor, which is correspondingly arranged at a position between the second container and the first valve on the first sub-pipeline, and is used to monitor whether there are bubbles when the physiological saline passes through, so as to confirm whether the first sub-pipeline is leaking; and a second ultrasonic bubble sensor, which is disposed on the first sub-pipeline at a position between the second syringe and the externally connected indwelling needle, and is used to monitor whether there is air or large bubbles passing through during the injection of the foaming liquid and the saline solution to ensure injection safety; and / or The foaming test device further includes a first thrust sensor, which is arranged corresponding to the piston of the first syringe and is used to sense the injection thrust of the first syringe when the foaming liquid is mixed or the first syringe injects the liquid into the human body, so as to ensure injection safety; and The second thrust sensor is arranged corresponding to the piston of the second syringe and is used to sense the injection thrust of the second syringe when the foaming liquid is mixed or when the second syringe injects the liquid into the human body, so as to ensure injection safety.

7. A foaming test system, characterized in that: The system comprises the foaming test device according to any one of claims 1 to 6; and A mixing device, the mixing device is used to drive the first container to move, so that the contrast agent contained in the first container is fully dissolved in the physiological saline to form a uniform left atrium contrast mixed solution, and to make the left atrium contrast mixed solution foam; Wherein, the mixing device is integrated on the foaming test device, or the mixing device is independent of the foaming test device.

8. The foaming test system according to claim 7, characterized in that: The mixing device comprises a driving member and a receiving member, wherein the receiving member is connected to the output shaft of the driving member; The receiving member is structured to form a receiving groove for receiving the first container. The receiving member, driven by the driving member, drives the first container to reciprocate along the axial direction of the output shaft and / or reciprocate along the circumferential direction of the output shaft.

9. The foaming test system according to claim 8, characterized in that: The mixing device further comprises a fixing assembly, and the fixing assembly is used to install and fix the driving member; and A roller, the roller being rotatably disposed on one of the fixing assembly and the receiving member and facing the other of the fixing assembly and the receiving member; Among them, a groove is provided at the other corresponding roller of the fixing component and the receiving member. Under the forward and reverse reciprocating drive of the driving member, the roller changes its position on the groove wall to make the receiving member reciprocate along the axial direction of the output shaft and reciprocate along the circumferential direction of the output shaft.

10. The foaming test system according to claim 9, characterized in that: The driving member comprises a driving body and the output shaft; The fixing assembly includes a bracket and a fixing member, the driving body is fixedly connected to the bracket and the fixing member through a locking member, the output shaft passes through the bracket and the fixing member in sequence and extends out of the fixing member to be connected to the receiving member, and the bracket is used to fix the mixing device; The two rollers are rotatably disposed on one side of the fixing member facing the receiving member, and the receiving member is structured to form the groove; The receiving member has a first position and a second position relative to the driving member along the axial direction of the output shaft, and the receiving member reciprocates between the first position and the second position under the driving of the driving member; When the receiving member is in the first position, the two rollers are respectively located at the lowest point of the groove, and the receiving member is close to the fixing assembly; When the receiving member is at the second position, the two rollers are respectively located at the highest points of the grooves, and the receiving member is away from the fixing assembly.

11. The foaming test system according to any one of claims 8 to 10, characterized in that: The driving member drives the receiving member to switch the rotation direction after each 180 degree rotation along the output shaft; and / or The mixing device further comprises a flexible member, and the flexible member is arranged on the groove wall of the accommodating groove.

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