Botanical sleep-aiding composition as well as preparation method and application thereof

Abstract

The invention discloses a botanical sleep-aiding composition and a preparation method and application thereof, and relates to the technical field of sleep-aiding products, the preparation method comprises the following steps: S1, taking spina date seeds, poria cocos, wheat, dried ginger and oyster shells in parts by weight, uniformly mixing, and stir-frying to obtain a first material; s2, mixing and grinding the first material and hot water to obtain first slurry; s3, deacetylated chitin is added into the first slurry, nitrogen is introduced, stirring is performed, and second slurry is obtained; s4, carrying out centrifugal treatment on the second slurry, and carrying out reduced pressure evaporation and concentration on the collected supernatant until the volume is 1 / 3 of the original volume to obtain a concentrated solution; and S5, mixing the concentrated solution with the aloe extract to obtain the plant-derived sleep-assisting composition. Through reasonable matching and treatment of the medicinal materials, effective components in the medicinal materials can be fully released, the bioavailability of the medicinal materials can be effectively improved, and the effect of improving the sleep quality can be remarkably improved.

Description

Technical Field

[0001] The present invention relates to the technical field of sleep-aiding products, and in particular to a plant-based sleep-aiding composition and a preparation method and application thereof. Background Art

[0002] In today's fast-paced social environment, the mental stress faced by individuals continues to rise, resulting in increasingly poor sleep quality, which seriously affects people's mental state during the day. Therefore, many people use Chinese medicine prescriptions such as Suanzaoren Decoction, Guipi Decoction, and Wendan Decoction to regulate their bodies and improve sleep quality. However, these Chinese medicine prescriptions are mainly taken in the form of decoctions, and the residues still contain many effective ingredients that have not been dissolved, which not only reduces the bioavailability of the medicinal materials, but also weakens the effect of the decoctions in improving sleep quality. Summary of the invention

[0003] The purpose of the present invention is to overcome the shortcomings of the prior art. The present invention provides a plant-based sleep-aiding composition and a preparation method and application thereof. By reasonably matching and processing medicinal materials, the effective ingredients in the medicinal materials can be fully released, which can not only effectively improve the bioavailability of the medicinal materials, but also significantly improve the effect of improving sleep quality.

[0004] The present invention provides a method for preparing a plant-based sleep-aiding composition, comprising the following steps:

[0005] S1. Take 10-20 parts of Chinese date seeds, 6-9 parts of Poria cocos, 6-9 parts of wheat, 3-5 parts of dried ginger and 3-5 parts of oyster shells, mix them evenly, and stir-fry them at 60-80° C. for 30-50 min to obtain the first material;

[0006] S2, mixing and grinding the first material and 2 to 3 times the volume of hot water to obtain a first slurry;

[0007] S3, adding 0.1-0.3 wt% of chitosan to the first slurry, and introducing nitrogen and stirring for at least 1 hour to obtain a second slurry;

[0008] S4, centrifuging the second slurry, and concentrating the collected supernatant by reduced pressure evaporation to one third of the original volume to obtain a concentrated solution;

[0009] S5. Mixing the concentrated solution and the aloe extract in a volume ratio of 1:5 to 5:1 to obtain a plant-based sleep-aiding composition.

[0010] Specifically, before step S1, the method further includes:

[0011] Wetting Poria cocos with glutinous rice wine, frying and drying at 80-90°C, and letting it cool for later use; and / or

[0012] Soak dried ginger in glutinous rice vinegar, fry and dry at 110-120℃, and let it cool for later use.

[0013] Specifically, in step S1, before the frying, the sour jujube seeds, the poria cocos, the wheat, the dried ginger and the oyster shell are crushed.

[0014] Specifically, in step S2, the temperature of the hot water is greater than 90°C.

[0015] Specifically, in step S3, the flow rate of the nitrogen is in the range of 50 to 60 cubic decimeters per hour.

[0016] Specifically, in step S4, the rotation speed range of the centrifugal treatment is 10000-15000 rpm.

[0017] Specifically, in step S5, the aloe vera extract is an aloe vera extract with a purity of 92-99%.

[0018] Specifically, in step S5, it also includes:

[0019] Cherry extract and banana extract are added to the mixture of the concentrated solution and the aloe extract, wherein the amount of the cherry extract added is 5-15wt% of the mass of the concentrated solution, and the amount of the banana extract added is 10-20wt% of the mass of the concentrated solution.

[0020] The present invention also provides a plant-based sleep-assisting composition, which is prepared by the preparation method of the plant-based sleep-assisting composition.

[0021] The present invention also provides an application of the plant-based sleep-aiding composition in the preparation of cosmetics or health products for assisting sleep. When used in the preparation of cosmetics for assisting sleep, in the plant-based sleep-aiding composition, the concentrated solution and the aloe extract are mixed in a volume ratio of 5:1 to 5; when used in the preparation of health products for assisting sleep, in the plant-based sleep-aiding composition, the concentrated solution and the aloe extract are mixed in a volume ratio of 1:1 to 5.

[0022] Compared with the prior art, the present invention has the following beneficial effects:

[0023] In the preparation method of the plant-based sleep-aiding composition of the present invention, the medicinal materials are reasonably matched, and 10-20 parts of Chinese jujube seeds, 6-9 parts of Poria cocos, 6-9 parts of wheat and 3-5 parts of oyster shells are combined, which can effectively enhance the tranquilizing effect, thereby achieving a calming and hypnotic effect, and the effect of assisting sleep is excellent; dried ginger is spicy, and the spicy taste of 3-5 parts of dried ginger is more suitable, which can not only promote blood circulation and accelerate the body's absorption of the plant-based sleep-aiding composition, but also give people a warm sensory feeling, which can effectively help people fall asleep.

[0024] The spinulosa jujuba seeds, poria cocos, wheat, oyster shells and dried ginger are evenly mixed, fried, ground into pulp with hot water, chitosan is added and nitrogen is stirred, centrifuged to concentrate the supernatant, and mixed with aloe vera extract, etc., so that the effective ingredients in the medicinal materials are fully released. A composition with good auxiliary sleep effect can be made, which can not only effectively improve the bioavailability of the medicinal materials, but also significantly improve the effect of improving sleep quality. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0026] Figure 1 The figure is a schematic flow chart of a method for preparing a plant-derived composition for assisting sleep according to an embodiment of the present invention. DETAILED DESCRIPTION

[0027] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0028] The present invention provides a method for preparing a plant-based sleep-aiding composition. Figure 1 The schematic flow chart of the preparation method of the plant-derived sleep-aiding composition in an embodiment of the present invention is shown, comprising the following steps:

[0029] S1. Take 10-20 parts of Chinese date seeds, 6-9 parts of Poria cocos, 6-9 parts of wheat, 3-5 parts of dried ginger and 3-5 parts of oyster shells, mix them evenly, and stir-fry them at 60-80° C. for 30-50 min to obtain the first material;

[0030] Specifically, Chinese jujube seeds can nourish the heart and liver, improve symptoms such as insomnia, dreaminess, palpitations, and it also has a good effect on alleviating restlessness; Poria cocos has the effect of nourishing the heart and calming the mind, helps to improve sleep quality, and relieves negative emotions such as irritability and anxiety; wheat is sweet and flat in nature, and has the effect of nourishing the heart and calming the mind, and is suitable for restlessness, insomnia and other symptoms; oyster shell enters the heart meridian, has the effect of calming and calming the mind, and can be used to treat symptoms such as palpitations, insomnia, and restlessness; dried ginger is pungent and hot in nature, and can warm the middle, expel cold, and restore yang and unblock the meridians.

[0031] The combination of 10-20 parts of Chinese jujube seeds, 6-9 parts of Poria cocos, 6-9 parts of wheat and 3-5 parts of oyster shells can effectively enhance the tranquilizing effect, thereby achieving a calming and hypnotic effect, and has an excellent effect in assisting sleep; dried ginger is spicy, and the spicy taste of 3-5 parts of dried ginger is more suitable, which can not only promote blood circulation and accelerate the body's absorption of the plant-based sleep-assisting composition, but also give people a warm sensory feeling, which can effectively help people fall asleep.

[0032] Furthermore, frying at 60-80°C for 30-50 minutes can make the effective ingredients in the medicinal materials more easily dissolve, which is beneficial to improving the bioavailability of the drug; it can also reduce certain irritating components in the medicinal materials, thereby further improving the smell of the medicinal materials and adding a pleasant medicinal fragrance to the plant-based sleep-aiding composition; in addition, this can also sterilize and disinfect, ensuring the stable quality of the slurry obtained by subsequent grinding.

[0033] In some specific embodiments, before step S1, the method further includes: wetting the Poria with glutinous rice wine, frying and drying at 80-90°C, and cooling for later use. After being processed with glutinous rice wine, the efficacy of the Poria is enhanced, and it can better play its role in nourishing the heart and calming the nerves; at the same time, after being processed with glutinous rice wine, the Poria absorbs the sweet taste of the glutinous rice wine, which is conducive to adding a pleasant sweet aroma to the prepared plant-based sleep-aiding composition. Preferably, the Poria is moistened with glutinous rice wine, fried and dried at 80-83°C, the temperature is gentle, and it is not easy to burn.

[0034] Specifically, the mass ratio of glutinous rice wine to Poria cocos is in the range of 1:5-10, and the alcohol concentration of glutinous rice wine is in the range of 15%vol-20%vol, which has a good effect on the processing of Poria cocos. Preferably, the mass ratio of glutinous rice wine to Poria cocos is 1:7, and the alcohol concentration of glutinous rice wine is 18%vol. The surface of the processed Poria cocos is yellow-brown, and the burnt aroma and sweet aroma of wine are obvious.

[0035] In some specific embodiments, before step S1, the method further includes: soaking the dried ginger with glutinous rice vinegar, frying and drying at 110-120°C, and cooling for later use. After the dried ginger is processed with glutinous rice vinegar, it can not only increase the solubility of the effective ingredients in the dried ginger, but also reduce the irritation of the dried ginger itself, making the spicy taste softer, and not easily causing a hot and tingling sensation while giving people a warm feeling. Preferably, soaking the dried ginger with glutinous rice vinegar, frying and drying at 115-120°C, the high temperature is conducive to the rapid evaporation of water.

[0036] Specifically, the mass ratio of glutinous rice vinegar to dried ginger is in the range of 1:8-12, the acetic acid content of glutinous rice vinegar is in the range of 3wt%-8wt%, and the processing effect on dried ginger is good. Preferably, the mass ratio of glutinous rice vinegar to dried ginger is 1:10, the acetic acid content of glutinous rice vinegar is 6wt%, and the processed dried ginger has a brown surface, a crisp texture, and a special aroma.

[0037] In some specific embodiments, in step S1, before the stir-frying, the Chinese date seeds, the Poria cocos, the wheat, the dried ginger and the oyster shell are crushed, which is beneficial to improving the processing effect and is also convenient for subsequent grinding and pulping.

[0038] S2, mixing and grinding the first material and 2 to 3 times the volume of hot water to obtain a first slurry;

[0039] During the mixing and grinding process, the calcium carbonate in the oyster shell can adjust the pH value of the slurry to prevent the slurry from becoming acidic, which is beneficial to improving the quality of the first slurry obtained.

[0040] The volume of hot water is 2 to 3 times that of the first material, which can fully dissolve the effective ingredients of the medicinal materials during the grinding process; at the same time, the amount of water is not too much, which is convenient for subsequent concentration operations.

[0041] In some specific embodiments, the temperature of the hot water is greater than 90°C, which can soften the first material and facilitate grinding and slurrying of the first material; moreover, 90°C is higher than the outlet temperature of the first material, which will not weaken the medicinal properties of the first material, and can also inhibit the reproduction of microorganisms and ensure the quality of the first slurry.

[0042] In some specific embodiments, after obtaining the first slurry, the first slurry is subjected to ultrasonic treatment for 3 to 5 minutes while it is hot; the strong cavitation effect, mechanical vibration, disturbance effect, diffusion and stirring effect generated by ultrasound are used to further dissolve the effective ingredients in the first slurry, and the properties of the first slurry are significantly optimized, while ensuring the uniform distribution of the first slurry components and eliminating possible agglomeration or precipitation. Specifically, the ultrasonic frequency range of the ultrasonic treatment is 20 to 30 kHz, and the cavitation effect is extremely strong.

[0043] S3, adding 0.1-0.3 wt% of chitosan to the first slurry, and introducing nitrogen and stirring for at least 1 hour to obtain a second slurry;

[0044] Chitosan has a good antibacterial effect and can effectively extend the shelf life of the plant-based sleep aid composition. Stirring with nitrogen can promote the dissolution of chitosan on the one hand, and on the other hand, it can promote the cooling of the slurry, and can also remove oxygen in the slurry, reduce the contact opportunity between the slurry and oxygen, and is also conducive to extending the shelf life of the plant-based sleep aid composition.

[0045] Preferably, 0.2 wt % of deacetylated chitosan is added to the first slurry, and nitrogen is introduced and stirred for 1.7 hours to obtain a second slurry; this operation not only ensures the full dissolution and dispersion of deacetylated chitosan in the slurry, but also further promotes the cooling and deoxygenation effects of the slurry through long-term nitrogen stirring, thereby maximizing the shelf life of the plant-based sleep aid composition and ensuring the stability and safety of the product.

[0046] In some specific embodiments, the flow rate of the nitrogen is in the range of 50 to 60 cubic decimeters per hour, which can form a large number of bubbles that are evenly distributed and rise rapidly in the slurry, which can not only achieve a good stirring effect, but also effectively reduce the oxygen content of the slurry. Specifically, the flow rate of the nitrogen is 55 cubic decimeters per hour, which will not cause splashing of the slurry.

[0047] S4, centrifuging the second slurry, and concentrating the collected supernatant by reduced pressure evaporation to one third of the original volume to obtain a concentrated solution;

[0048] Specifically, the rotation speed range of the centrifugal treatment is 10000~15000rpm. If the rotation speed is less than 10000rpm, the medicinal residue cannot be completely precipitated, resulting in the supernatant still containing more impurities, which will reduce the quality of the supernatant; if the rotation speed is greater than 15000rpm, it is easy for some effective ingredients to precipitate together with the medicinal residue due to excessive centrifugal force, which will also reduce the quality of the supernatant.

[0049] Specifically, the collected supernatant is poured into an evaporator, and the evaporator is evacuated to maintain a vacuum degree of 200-400 Pa, which helps to reduce the temperature of water evaporation, improve evaporation efficiency, and reduce the loss of effective ingredients. Further, the supernatant is evaporated and concentrated at 70-80°C. This temperature range can both ensure evaporation efficiency and reduce the loss of active ingredients.

[0050] Concentrating the supernatant to one third of its original volume not only increases the concentration of active ingredients in the supernatant, but also provides high-quality concentrate for subsequent processing or application.

[0051] S5, mixing the concentrated solution and the aloe extract in a volume ratio of 1:5 to 5:1 to obtain a plant-based sleep-aiding composition;

[0052] Aloe vera extract can be eaten or used externally, and it has a certain viscosity. This property makes it an ideal matrix material that can effectively disperse and carry the active ingredients in the concentrate. By mixing the concentrate with the aloe vera extract, not only can the uniform distribution of the active ingredients in the composition be ensured, but the viscosity of the aloe vera extract can also be used to adjust the overall texture of the composition, making it more suitable for different application scenarios and user needs.

[0053] Aloe vera extract is rich in a variety of nutrients that are beneficial to the human body, such as polysaccharides, amino acids, vitamins, etc. These ingredients can further enhance the effect of the plant-based sleep-aiding composition; when the composition is applied externally, these nutrients in the aloe vera extract can nourish the skin and improve skin condition, thereby providing users with a more comprehensive and comfortable experience; when the composition is taken orally, these nutrients in the aloe vera extract can cool down and purge heat, strengthen the stomach and regulate the intestines, and are beneficial to improving human immunity.

[0054] In some specific embodiments, the aloe extract is an aloe vera extract with a purity of 92-99%. Compared with other aloe vera extracts, the aloe vera extract is mild, non-irritating and has good safety.

[0055] In some specific embodiments, in step S5, it further includes: adding cherry extract and banana extract to the mixture of the concentrate and the aloe extract, wherein the amount of cherry extract added is 5-15wt% of the mass of the concentrate, and the amount of banana extract added is 10-20wt% of the mass of the concentrate. Cherry extract contains rich tryptophan and serotonin, as well as more melatonin, which can effectively improve people's sleep; banana extract contains rich tryptophan, which can also improve people's sleep; and cherry extract and banana extract are both rich in vitamins, trace elements, etc., which are beneficial to human health.

[0056] When the composition is used externally, such as a moisturizing cream or essence lotion, the cherry extract is added in an amount of 10-15wt% of the mass of the concentrate, and the banana extract is added in an amount of 15-20wt% of the mass of the concentrate. This amount can ensure that the active ingredients in the extract can fully penetrate the skin and play a role in assisting sleep.

[0057] When the composition is taken orally, such as made into health products such as oral liquid or capsules, the added amount of the cherry extract is 5-10wt% of the mass of the concentrated liquid, and the added amount of the banana extract is 10-15wt% of the mass of the concentrated liquid. The absorption effect of oral administration is good, and the added amount can be reduced.

[0058] The preparation method of the plant-based sleep-aiding composition of the present invention comprises the following steps: uniformly mixing Chinese jujube seeds, Poria cocos, wheat, oyster shells and dried ginger, reasonably matching the medicinal materials, and performing the steps of frying, grinding and pulping with heated water, adding deacetylated chitosan and stirring with nitrogen, centrifuging and concentrating the supernatant, and mixing with aloe extract, so that the effective ingredients in the medicinal materials are fully released, and a composition with good sleep-aiding effect can be prepared, which can not only effectively improve the bioavailability of the medicinal materials, but also significantly improve the effect of improving sleep quality; moreover, the prepared plant-based sleep-aiding composition has good safety and a long shelf life, can be taken orally, and can also be used externally, and is suitable for different application scenarios and user needs.

[0059] The present invention also provides a plant-based sleep-aiding composition, which is prepared by the preparation method of the plant-based sleep-aiding composition, and the plant-based sleep-aiding composition can be irradiated and sterilized to extend its shelf life. Specifically, the radiation dose of irradiation sterilization is 1 to 5 kGy, which can effectively eliminate microorganisms in the plant-based sleep-aiding composition.

[0060] The present invention also provides an application of the plant-based sleep-aiding composition in the preparation of sleep-aiding cosmetics or health-care products. The plant-based sleep-aiding composition is easy to use, and the plant-based sleep-aiding composition can be directly added to the cosmetics or health-care products, or the plant-based sleep-aiding composition can be freeze-dried into powder and then added to the cosmetics or health-care products.

[0061] Specifically, when used in the preparation of cosmetics for assisting sleep, in the plant-based sleep-assisting composition, the concentrated solution and the aloe vera extract are mixed in a volume ratio of 5:1-5, which can ensure that the effective ingredients of the concentrated solution can fully penetrate the skin and play a role in assisting sleep; when used in the preparation of health care products for assisting sleep, in the plant-based sleep-assisting composition, the concentrated solution and the aloe vera extract are mixed in a volume ratio of 1:1-5, and the absorption effect of the concentrated solution is good when taken orally, which can reduce the amount of concentrated solution added.

[0062] Example 1

[0063] (1) By weight, 15 parts of Chinese jujube seeds, 8 parts of Poria cocos, 7 parts of wheat, 4 parts of dried ginger and 4 parts of oyster shells were mixed evenly, and fried at 70° C. for 40 minutes to obtain a first material;

[0064] (2) mixing and grinding the first material and 2.5 times the volume of hot water to obtain a first slurry;

[0065] (3) adding 0.2 wt % of deacetylated chitosan to the first slurry, introducing nitrogen and stirring for 1 h to obtain a second slurry;

[0066] (4) centrifuging the second slurry, and concentrating the collected supernatant by evaporation under reduced pressure to one third of the original volume to obtain a concentrated solution;

[0067] (5) The concentrated solution and the aloe vera extract are mixed in a volume ratio of 1:3 to obtain a plant-based sleep-aiding composition.

[0068] Animal Experimentation:

[0069] The experimenters evaluated the effect of the plant-based sleep-aiding composition of Example 1 on the sleep of mice through the sodium pentobarbital subthreshold dose sleep experiment, the sodium pentobarbital prolonged sleep time experiment, and the sodium pentobarbital sleep latency experiment.

[0070] 150 SPF healthy adult male mice (weight 20±2g) were randomly divided into three groups, A, B, and C, with 50 mice in each group; among them, group A was subjected to the subthreshold dose sleep experiment of sodium pentobarbital, group B was subjected to the extended sleep time experiment of sodium pentobarbital, and group C was subjected to the sodium pentobarbital sleep latency experiment. Each batch of mice was randomly divided into a negative control group, a low-dose group, a medium-dose group, a high-dose group, and a positive control group, with 10 mice in each group; among them, the negative control group was given 180mg / kg.bw normal saline by gavage, the low-dose group was given 60mg / kg.bw composition by gavage, the medium-dose group was given 120mg / kg.bw composition by gavage, the high-dose group was given 180mg / kg.bw composition by gavage, and the positive control group was given 0.01mg / kg.bw melatonin by gavage. Mice in each group were gavaged once a day, with a gavage volume of 0.2mL / 10g·bw, and the gavage was continued for 30 days.

[0071] (1) Subthreshold dose sleep experiment of sodium pentobarbital: 30 min after the last oral administration of the drug to mice in each group of batch A, each group of mice was intraperitoneally injected with 30 mg / kg.bw sodium pentobarbital (the injection volume was 0.1 mL / 10 g.bw). The number of mice in each group that fell asleep was observed and recorded, and the incidence of sleep was calculated. The results are shown in Table 1.

[0072]

[0073] Note: Compared with the negative control group, ** indicates P < 0.01, * indicates P < 0.05.

[0074] As can be seen from Table 1, although the effects of improving the sleep incidence of mice in the low-dose group, medium-dose group and high-dose group were weaker than those in the positive control group, the sleep incidence of mice in the medium-dose group and high-dose group was significantly higher than that in the negative control group, which shows that taking a certain amount of plant-based sleep-aiding composition can effectively improve the sleep incidence of mice.

[0075] (2) Experiment on prolonging sleep time of sodium pentobarbital: 30 minutes after the last oral administration of each group of mice in batch B, each group of mice was intraperitoneally injected with 50 mg / kg.bw sodium pentobarbital (the injection volume was 0.1 mL / 10 g.bw). The sleep time of each group of mice was observed and recorded. The results are shown in Table 2.

[0076]

[0077] Note: Compared with the negative control group, ** indicates P < 0.01, * indicates P < 0.05.

[0078] As can be seen from Table 2, although the effects of the low-dose group, medium-dose group and high-dose group on extending the sleep time of mice were weaker than those of the positive control group, the sleep time of mice in the medium-dose group was significantly higher than that of the negative control group, indicating that ingesting a certain amount of a plant-based sleep-aiding composition can effectively prolong the sleep time of mice.

[0079] (3) Sodium barbital sleep latency experiment: 30 minutes after the last oral administration of the mice in each group of batch C, each group of mice was intraperitoneally injected with 280 mg / kg.bw sodium barbital (the injection volume was 0.1 mL / 10 g.bw). The sleep latency of each group of mice was observed and recorded. The results are shown in Table 3.

[0080]

[0081] Note: Compared with the negative control group, ** indicates P < 0.01, * indicates P < 0.05.

[0082] It can be seen from Table 3 that although the effects of shortening the sleep latency of mice in the low-dose group, medium-dose group and high-dose group were weaker than those in the positive control group, the sleep latency of mice in the medium-dose group was significantly shorter than that in the negative control group, which indicates that ingesting a certain amount of plant-based sleep-aiding composition can effectively shorten the sleep latency of mice.

[0083] in conclusion

[0084] The results of the sodium pentobarbital subthreshold dose sleep experiment, the sodium pentobarbital sleep time extension experiment and the sodium pentobarbital sleep latency experiment showed that the plant-based sleep-aiding composition of Example 1 can effectively improve the sleep condition of mice, increase the incidence of sleep in mice, prolong the sleep time of mice, and shorten the sleep latency of mice.

[0085] Example 2

[0086] (1) By weight, 15 parts of Chinese jujube seeds, 8 parts of Poria cocos, 7 parts of wheat, 4 parts of dried ginger and 4 parts of oyster shells were mixed evenly, and fried at 70° C. for 40 minutes to obtain a first material;

[0087] (2) mixing and grinding the first material and 2.5 times the volume of hot water to obtain a first slurry;

[0088] (3) adding 0.2 wt % of deacetylated chitosan to the first slurry, introducing nitrogen and stirring for 1 h to obtain a second slurry;

[0089] (4) centrifuging the second slurry, and concentrating the collected supernatant by evaporation under reduced pressure to one third of the original volume to obtain a concentrated solution;

[0090] (5) The concentrated solution and the aloe vera extract are mixed in a volume ratio of 3:1 to obtain a plant-based sleep-aiding composition.

[0091] The plant-based sleep aid composition of Example 2 is made into a skin softener: by mass percentage, 30% of the plant-based sleep aid composition, 16% of glycerin, 15% of carbomer, 1.3% of butylene glycol, 1.2% of propylene glycol, 0.8% of caprylyl glycol, 0.5% of vitamin D, 0.3% of vitamin E, and deionized water are added to 100%, and the mixture is stirred and mixed to obtain a skin softener.

[0092] We recruited 40 volunteers (whose sleep monitoring score of Xiaomi wristband was less than 80 points) to use the softener before going to bed for 35 consecutive days, and collected 36 effective feedbacks:

[0093] All volunteers reported that they felt warm and comfortable when using it, making them feel lazy.

[0094] All volunteers did not experience any abnormal phenomena such as redness, swelling, stinging, itching, burning sensation, peeling, etc. during use;

[0095] After 10 consecutive days of use, the sleep monitoring scores of three-quarters of the volunteers reached above 85 points; after 20 consecutive days of use, the sleep monitoring scores of all volunteers reached above 90 points; after 30 consecutive days of use, the sleep monitoring scores of all volunteers stabilized between 92 and 95 points.

[0096] in conclusion

[0097] The plant-derived sleep-aiding composition of Example 2 can be used in cosmetics to effectively improve people's sleep quality; moreover, it is safe, mild and non-irritating.

[0098] The above is a detailed introduction to a plant-based sleep-aiding composition provided by an embodiment of the present invention, as well as its preparation method and application. Specific examples are used herein to illustrate the principles and implementation methods of the present invention. The description of the above embodiments is only used to help understand the method of the present invention and its core idea. At the same time, for a person skilled in the art, according to the idea of ​​the present invention, there will be changes in the specific implementation method and application scope. In summary, the content of this specification should not be understood as a limitation on the present invention.

Claims

1. A method for preparing a plant-based sleep-aiding composition, characterized in that: The following steps are involved: S1. Take 10-20 parts of Chinese date seeds, 6-9 parts of Poria cocos, 6-9 parts of wheat, 3-5 parts of dried ginger and 3-5 parts of oyster shells, mix them evenly, and stir-fry them at 60-80° C. for 30-50 min to obtain the first material; S2, mixing and grinding the first material and 2 to 3 times the volume of hot water to obtain a first slurry; S3, adding 0.1-0.3 wt% of chitosan to the first slurry, and introducing nitrogen and stirring for at least 1 hour to obtain a second slurry; S4, centrifuging the second slurry, and concentrating the collected supernatant by reduced pressure evaporation to one third of the original volume to obtain a concentrated solution; S5. Mixing the concentrated solution and the aloe extract in a volume ratio of 1:5 to 5:1 to obtain a plant-based sleep-aiding composition.

2. The method for preparing the plant-derived sleep-aiding composition according to claim 1, characterized in that: Before step S1, the method further includes: Wetting Poria cocos with glutinous rice wine, frying and drying at 80-90°C, and letting it cool for later use; and / or Soak dried ginger in glutinous rice vinegar, fry and dry at 110-120℃, and let it cool for later use.

3. The method for preparing the plant-derived sleep-aiding composition according to claim 1, characterized in that: In step S1, before the frying, the spiny jujube seeds, the poria cocos, the wheat, the dried ginger and the oyster shell are crushed.

4. The method for preparing the plant-derived sleep-aiding composition according to claim 1, characterized in that: In step S2, the temperature of the hot water is greater than 90°C.

5. The method for preparing the plant-derived sleep-aiding composition according to claim 1, characterized in that: In step S3, the flow rate of the nitrogen is in the range of 50 to 60 cubic decimeters per hour.

6. The method for preparing the plant-derived sleep-aiding composition according to claim 1, characterized in that: In step S4, the rotation speed range of the centrifugal treatment is 10000-15000 rpm.

7. The method for preparing the plant-derived sleep-aiding composition according to claim 1, characterized in that: In step S5, the aloe vera extract is an aloe vera extract with a purity of 92-99%.

8. The method for preparing the plant-derived sleep-aiding composition according to claim 1, characterized in that: In step S5, it also includes: Cherry extract and banana extract are added to the mixture of the concentrated solution and the aloe extract, wherein the amount of the cherry extract added is 5-15wt% of the mass of the concentrated solution, and the amount of the banana extract added is 10-20wt% of the mass of the concentrated solution.

9. A plant-derived composition for aiding sleep, characterized in that: The plant-derived sleep-aiding composition is prepared by the preparation method of the plant-derived sleep-aiding composition according to any one of claims 1 to 8.

10. Use of the plant-derived sleep-aiding composition according to claim 9 in the preparation of sleep-aiding cosmetics or health products, characterized in that: When used in preparing cosmetics for assisting sleep, in the plant-based sleep-assisting composition, the concentrate and the aloe extract are mixed in a volume ratio of 5:1-5; When used in preparing a health product for assisting sleep, in the plant-based composition for assisting sleep, the concentrated solution and the aloe extract are mixed in a volume ratio of 1:1 to 5.

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