Traditional Chinese medicine composition for improving benign prostatic hyperplasia as well as preparation method and application of traditional Chinese medicine composition

Abstract

The invention provides a traditional Chinese medicine composition for improving benign prostatic hyperplasia and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition comprises the following components in parts by weight: 15-25 parts of Chinese yam, 15-25 parts of rhizoma smilacis glabrae, 15-25 parts of semen coicis, 10-20 parts of radix salviae miltiorrhizae, 10-20 parts of fructus trichosanthis, 10-20 parts of corn stigma, 5-15 parts of radix morindae officinalis, 5-15 parts of herba cistanche, 5-15 parts of cortex eucommiae, 5-15 parts of rhizoma imperatae, 5-15 parts of herba taraxaci and 5-15 parts of cassia twig. The components of the traditional Chinese medicine composition are synergistically compatible, so that prostatic hyperplasia can be remarkably improved, further damage and malignant transformation of tissues are relieved, body functions are relatively comprehensively improved, and the effective rate is extremely high. The traditional Chinese medicine composition disclosed by the invention is safe in formula, non-toxic and sustainable to take. In addition, the traditional Chinese medicine composition does not need additional syndrome differentiation during application, is suitable for prostatic hyperplasia caused by various causes, and has wide applicability.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for improving prostate hyperplasia, and a preparation method and application thereof. Background Art

[0002] Generally, prostate hyperplasia itself is not dangerous, but it can cause a series of functional disorders in the urethra, bladder and kidneys. There are many causes of prostate hyperplasia. Men are prone to varying degrees of prostate hyperplasia after a certain age. Frequent urination, urgency, increased nocturia and urge urinary incontinence are the main symptoms, which affect men's health and reduce their quality of life.

[0003] At present, the main treatment methods are hormone or anti-hormone drugs, α-adrenergic receptor blockers, 5α receptor reductase inhibitors, cholesterol inhibitors and other drugs or surgical treatment. The side effects of drugs are large and they are easy to become dependent on them. After long-term use, they cause great harm to the cardiovascular and cerebrovascular systems and the immune system. Western medicine is mainly used to improve and relieve symptoms rather than to cure prostate hyperplasia. Surgery is risky and expensive. When choosing a surgery, factors such as hospital conditions, doctor's surgical proficiency and experience should be considered. Moreover, surgical resection does not completely remove the prostate tissue, and the remaining prostate tissue in the body may still have lesions.

[0004] There are many prescriptions for the prevention and treatment of prostatic hyperplasia in traditional Chinese medicine. Traditional Chinese medicine believes that the location of urinary retention is in the prostate, but it is closely related to the lungs, spleen, liver, kidneys and triple energizer. Because prostatic hyperplasia is a disease of the elderly, the kidney qi of the elderly gradually declines, so this disease is mainly due to deficiency, and the deficiency is mainly kidney, and the superficial excess is mostly blamed on blood stasis. If the positive qi is insufficient and the evil is blocked, the urine will not pass. Mr. Sun Jigeng, a famous Chinese medicine expert, scientifically and systematically expounded the Chinese medicine special method for treating prostatic hyperplasia and chronic prostatitis-tonifying deficiency and removing blood stasis therapy. However, the syndrome differentiation of Chinese medicine is more complicated, not easy to master, and the effects of different people are different. Therefore, it is urgent to provide a Chinese medicine composition for the treatment of prostatic hyperplasia caused by different causes. Summary of the invention

[0005] In view of this, the object of the present invention is to provide a Chinese medicine composition for improving prostate hyperplasia and a preparation method and application thereof.

[0006] In order to achieve the above-mentioned object of the invention, the present invention provides the following technical solutions:

[0007] The invention provides a traditional Chinese medicine composition for improving prostate hyperplasia, comprising the following ingredients in parts by weight: 15-25 parts of yam, 15-25 parts of smilax glabra, 15-25 parts of coix seeds, 10-20 parts of salvia miltiorrhiza, 10-20 parts of trichosanthes, 10-20 parts of corn silk, 5-15 parts of Morinda officinalis, 5-15 parts of Cistanche deserticola, 5-15 parts of Eucommia ulmoides, 5-15 parts of Imperata root, 5-15 parts of dandelion and 5-15 parts of cassia twig.

[0008] Preferably, the following ingredients are included in parts by weight: 18-22 parts of yam, 18-22 parts of smilax glabra, 18-22 parts of coix seeds, 12-18 parts of salvia miltiorrhiza, 12-18 parts of whole trichosanthes, 12-18 parts of corn silk, 7-14 parts of Morinda officinalis, 7-14 parts of Cistanche deserticola, 7-14 parts of Eucommia ulmoides, 7-14 parts of Imperata rhizome, 7-14 parts of dandelion, and 7-14 parts of cassia twig.

[0009] Preferably, the following ingredients are included in parts by weight: 20 parts of yam, 20 parts of smilax glabra, 20 parts of coix seeds, 15 parts of salvia miltiorrhiza, 15 parts of whole trichosanthes, 15 parts of corn silk, 10 parts of Morinda officinalis, 10 parts of Cistanche deserticola, 10 parts of Eucommia ulmoides, 10 parts of Imperata root, 10 parts of dandelion, and 10 parts of cassia twig.

[0010] The present invention also provides a method for preparing the Chinese medicine composition, comprising the following steps:

[0011] 1) mixing the Chinese medicine and water 2 to 5 times the total weight of the Chinese medicine and soaking them, boiling them over high heat until the water boils, then switching to medium heat and continuing to boil for 10 to 30 minutes, filtering to obtain a filter residue and a first filtrate;

[0012] 2) mixing the filter residue of step 1) with water in an amount of 1 to 3 times the total mass of the Chinese medicine, boiling over high heat until the water boils, then switching to medium heat and continuing to boil for 10 to 30 minutes, filtering to obtain a second filtrate;

[0013] 3) Mixing the first filtrate and the second filtrate to obtain the Chinese medicine composition.

[0014] The present invention also provides the use of the Chinese medicine composition or the Chinese medicine composition prepared by the preparation method in preparing a medicine for improving prostate hyperplasia.

[0015] Preferably, the dosage form of the drug includes powder, tablet, granule, capsule, solution, emulsion, suspension.

[0016] Compared with the prior art, the present invention has the following beneficial effects:

[0017] The Chinese medicine composition of the present invention comprises yam, smilax glabra and coix seed as the main medicines, which have the effects of invigorating the spleen and removing dampness, softening and dispersing lumps; the salvia miltiorrhiza, whole trichosanthes and corn silk as the assistant medicines, which have the effects of excretion, anti-oxidation, anti-inflammatory and analgesic; the Morinda officinalis, Cistanche deserticola and Eucommia ulmoides as the adjuvant medicines, which have the effects of invigorating the kidney and restoring the power of the prostate; the Imperata root, dandelion and cassia twig as the guiding medicines, which have the effects of directly reaching the place, clearing away heat and detoxifying, and anti-inflammatory and analgesic; the synergistic compatibility of the components can significantly improve prostate hyperplasia, slow down further tissue damage and malignant transformation, and comprehensively improve body functions with extremely high efficiency.

[0018] The Chinese medicine composition of the present invention is safe, non-toxic, and can be taken continuously. Moreover, the Chinese medicine composition of the present invention does not require additional syndrome differentiation when used, is applicable to prostate hyperplasia caused by various causes, and has wide applicability. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 The B-ultrasound examination report of the patient in Case 1 before taking the Chinese medicine composition of Example 1;

[0020] Figure 2 The B-ultrasound examination report of the patient in Case 1 after taking the Chinese medicine composition of Example 1;

[0021] Figure 3 The B-ultrasound examination report of the patient in Case 2 before taking the Chinese medicine composition of Example 1;

[0022] Figure 4 The B-ultrasound examination report of the patient in Case 2 after taking the Chinese medicine composition of Example 1;

[0023] Figure 5 The B-ultrasound examination report of the patient in Case 3 before taking the Chinese medicine composition of Example 1;

[0024] Figure 6 The B-ultrasound examination report of the patient in Case 3 after taking the Chinese medicine composition of Example 1;

[0025] Figure 7 The B-ultrasound examination report of the patient in Case 4 before taking the Chinese medicine composition of Example 1;

[0026] Figure 8 The B-ultrasound examination report of the patient in Case 4 after taking the Chinese medicine composition of Example 1;

[0027] Fig. 9 The B-ultrasound examination report of the patient in Case 5 before taking the Chinese medicine composition of Example 1;

[0028] Fig.10 The B-ultrasound examination report of the patient in Case 5 after taking the Chinese medicine composition of Example 1;

[0029] Fig.11 The B-ultrasound examination report of the patient in Case 6 before taking the Chinese medicine composition of Example 1;

[0030] Fig.12 It is the B-ultrasound examination report of the patient in Case 6 after taking the Chinese medicine composition of Example 1 for the first time;

[0031] Fig.13 The B-ultrasound examination report of the patient in Case 6 after continuing to take the Chinese medicine composition of Example 1;

[0032] Fig.14 The B-ultrasound examination report of the patient in Case 7 before taking the Chinese medicine composition of Example 1;

[0033] Fig.15 The B-ultrasound examination report of the patient in Case 7 after taking the Chinese medicine composition of Example 1;

[0034] Fig.16 The B-ultrasound examination report of the patient in Case 8 before taking the Chinese medicine composition of Example 1;

[0035] Fig.17 This is the B-ultrasound examination report of the patient in Case 8 after taking the Chinese medicine composition of Example 1. DETAILED DESCRIPTION

[0036] The invention provides a traditional Chinese medicine composition for improving prostate hyperplasia, comprising the following ingredients in parts by weight: 15-25 parts of yam, 15-25 parts of smilax glabra, 15-25 parts of coix seeds, 10-20 parts of salvia miltiorrhiza, 10-20 parts of trichosanthes, 10-20 parts of corn silk, 5-15 parts of Morinda officinalis, 5-15 parts of Cistanche deserticola, 5-15 parts of Eucommia ulmoides, 5-15 parts of Imperata root, 5-15 parts of dandelion and 5-15 parts of cassia twig.

[0037] In the present invention, the amount of yam is preferably 18 to 22 parts, more preferably 20 parts;

[0038] The amount of the smilax glabra is preferably 18 to 22 parts, more preferably 20 parts;

[0039] The dosage of coix seed is preferably 18 to 22 parts, more preferably 20 parts;

[0040] The dosage of the salvia miltiorrhiza is preferably 12 to 18 parts, more preferably 15 parts;

[0041] The dosage of the whole Trichosanthes kirilowii is preferably 12 to 18 parts, more preferably 15 parts;

[0042] The amount of corn silk is preferably 12 to 18 parts, more preferably 15 parts;

[0043] The dosage of Morinda officinalis is preferably 7 to 14 parts, more preferably 10 parts;

[0044] The amount of Cistanche deserticola is preferably 7 to 14 parts, more preferably 10 parts;

[0045] The dosage of Eucommia ulmoides is preferably 7 to 14 parts, more preferably 10 parts;

[0046] The dosage of Imperata cylindrica root is preferably 7 to 14 parts, more preferably 10 parts;

[0047] The dosage of dandelion is preferably 7 to 14 parts, more preferably 10 parts;

[0048] The dosage of the cassia twig is preferably 7 to 14 parts, more preferably 10 parts.

[0049] The present invention also provides a method for preparing the Chinese medicine composition, comprising the following steps:

[0050] 1) mixing the Chinese medicine and water 2 to 5 times the total weight of the Chinese medicine and soaking them, boiling them over high heat until the water boils, then switching to medium heat and continuing to boil for 10 to 30 minutes, filtering to obtain a filter residue and a first filtrate;

[0051] 2) mixing the filter residue of step 1) with water in an amount of 1 to 3 times the total mass of the Chinese medicine, boiling over high heat until the water boils, then switching to medium heat and continuing to boil for 10 to 30 minutes, filtering to obtain a second filtrate;

[0052] 3) Mixing the first filtrate and the second filtrate to obtain the Chinese medicine composition.

[0053] In the present invention, the amount of water used in step 1) is preferably 3 to 4 times the total mass of the Chinese medicine; the time for continuing to decoct is preferably 15 to 25 minutes; the amount of water used in step 2) is preferably 2 times the total mass of the Chinese medicine; the time for continuing to decoct is preferably 15 to 25 minutes.

[0054] The present invention also provides the use of the Chinese medicine composition or the Chinese medicine composition prepared by the preparation method in preparing a drug for improving prostate hyperplasia. In the present invention, the dosage form of the drug includes powder, tablet, granule, capsule, solution, emulsion, suspension.

[0055] The technical solutions provided by the present invention are described in detail below in conjunction with the embodiments, but they should not be construed as limiting the protection scope of the present invention.

[0056] Example 1

[0057] A traditional Chinese medicine composition for improving prostate hyperplasia is composed of the following ingredients in parts by weight: 20g of yam, 20g of smilax glabra, 20g of coix seed, 15g of salvia miltiorrhiza, 15g of whole trichosanthes, 15g of corn silk, 10g of Morinda officinalis, 10g of Cistanche deserticola, 10g of Eucommia ulmoides, 10g of Imperata root, 10g of Taraxacum herb, and 10g of cassia twig.

[0058] The preparation method of the Chinese medicine composition is:

[0059] 1) mixing the Chinese medicine and water 3 times the total weight of the Chinese medicine and soaking them, boiling them over high heat until the water boils, then switching to medium heat and continuing to boil for 20 minutes, filtering to obtain a filter residue and a first filtrate;

[0060] 2) mixing the filter residue of step 1) with water twice the total mass of the Chinese medicine, boiling over high heat until the water boils, then switching to medium heat and continuing to boil for 20 minutes, filtering to obtain a second filtrate;

[0061] 3) Mixing the first filtrate and the second filtrate to obtain the Chinese medicine composition.

[0062] Example 2

[0063] A traditional Chinese medicine composition for improving prostate hyperplasia is composed of the following ingredients in parts by weight: 15g of yam, 15g of smilax glabra, 15g of coix seed, 10g of salvia miltiorrhiza, 10g of whole trichosanthes, 10g of corn silk, 5g of Morinda officinalis, 5g of Cistanche deserticola, 5g of Eucommia ulmoides, 5g of Imperata root, 5g of Taraxacum herb, and 5g of cinnamon twig.

[0064] The preparation method of the Chinese medicine composition is:

[0065] 1) mixing the Chinese medicine and water twice the total weight of the Chinese medicine and soaking them, boiling them over high heat until the water boils, then switching to medium heat and continuing to boil for 10 minutes, filtering to obtain a filter residue and a first filtrate;

[0066] 2) mixing the filter residue of step 1) with water of 1 times the total weight of the Chinese medicine, boiling over high heat until the water boils, then switching to medium heat and continuing to boil for 10 minutes, filtering to obtain a second filtrate;

[0067] 3) Mixing the first filtrate and the second filtrate to obtain the Chinese medicine composition.

[0068] Example 3

[0069] A traditional Chinese medicine composition for improving prostate hyperplasia, composed of the following ingredients in parts by weight: 25g of yam, 25g of smilax glabra, 25g of coix seed, 20g of salvia miltiorrhiza, 20g of whole trichosanthes, 20g of corn silk, 15g of Morinda officinalis, 15g of Cistanche deserticola, 15g of Eucommia ulmoides, 15g of Imperata root, 15g of dandelion, and 15g of cassia twig.

[0070] The preparation method of the Chinese medicine composition is:

[0071] 1) mixing the Chinese medicine and water 5 times the total weight of the Chinese medicine and soaking them, boiling them over high heat until the water boils, then switching to medium heat and continuing to boil for 30 minutes, filtering to obtain a filter residue and a first filtrate;

[0072] 2) mixing the filter residue of step 1) with water 3 times the total mass of the Chinese medicine, boiling over high heat until the water boils, then switching to medium heat and continuing to boil for 30 minutes, filtering to obtain a second filtrate;

[0073] 3) Mixing the first filtrate and the second filtrate to obtain the Chinese medicine composition.

[0074] Experimental Example 1

[0075] Case 1

[0076] Chen*Bao, male, 66 years old, retired cadre, has regular physical examination every year. The physical examination report in August 2020 showed that the prostate had a clear outline, about 4.2*3.3*3.0cm in size, uneven echo, and multiple strong spots inside, one of which was 0.7cm in size. He was diagnosed with an enlarged prostate with multiple calcifications (such as Figure 1 The calculated prostate volume is approximately: 41.58cm 3 , calcification foci 0.7cm. The health problems that troubled Mr. Chen were not limited to the prostate, but also had other problems. In the process of comprehensive improvement, it took 6 months for the overall health to improve, of which taking the Chinese medicine composition prepared in Example 1 improved for 1 month, taking it every day, 1 dose per day. After the body felt better, it stopped taking it. A physical examination in August 2021 showed: the prostate had a clear outline, about 4.1*2.9*2.8cm in size, uneven echo, and multiple strong light spots inside, one of which was about 0.4cm (such as Figure 2 The calculated prostate volume is approximately: 33.292 cm 3 , calcification focus 0.4cm. The volume of prostate is reduced by about 20%. It can be seen that the Chinese medicine composition of the present invention can effectively improve prostate hyperplasia.

[0077] Case 2

[0078] Ding*, male, 43 years old, works as a lawyer. He has many friends and social events and drinks more than 3 times a week. In the physical examination in March 2018, the results of gastroscopy were not very ideal. His heart, liver and lungs were damaged to varying degrees. He had crystals in both kidneys and a full prostate of 4.07*3.02*3.33cm (as shown in Figure 2). Figure 3 The calculated prostate volume is approximately 40.93 cm 3. Health requires holistic care. I started taking gastrointestinal medicine at the end of 2019, and I took the medicine intermittently for a total of one year. During the medication period, I did not reduce my social activities due to the medication, and my workload did not decrease. I felt that my health did not continue to decline, but improved slightly. During the maintenance period, Mr. Ding occasionally suffered from acute prostatitis. It took a total of 1 year for gastrointestinal improvement, and at the same time, I took the Chinese medicine composition prepared in Example 1 for 1 month, taking it every day, 1 dose per day. In the physical examination in March 2022, the left and right diameter of the prostate was about 3.9, the front and back diameter was about 2.8, the upper and lower diameter was about 3.0, and the calcification plaque was 0.3cm (such as Figure 4 The calculated prostate volume is approximately 32.76 cm 3 The volume of the prostate gland was reduced by about 20%. It can be seen that the Chinese medicine composition of the present invention can effectively improve prostate hyperplasia.

[0079] Case 3

[0080] Jin*yong, male, 49 years old, corporate executive, average workload, frequent social activities, and personal health. In May 2018, a physical examination showed that the prostate B-ultrasound showed a left-right diameter of 4.6, anterior-posterior diameter of 3.2, and superior-inferior diameter of 3.0, with uneven echo distribution, and multiple strong spots were seen inside, one of which was about 0.8 cm in size (such as Figure 5 The calculated prostate volume is approximately 44.16 cm 3 In March 2019, the patient started the maintenance and received comprehensive maintenance for 3 months, during which the Chinese medicine composition prepared in Example 1 was taken for 1 month, 1 dose per day. In July 2019, the B-ultrasound of the prostate was reviewed, showing that the left and right diameter of the prostate was 4.4, the front and back diameter was 2.6, and the upper and lower diameter was 2.9. The echo distribution was uniform, and multiple strong light spots were seen inside, the largest of which was 0.9 cm (such as Figure 6 The calculated prostate volume is approximately 33.18 cm 3 , the volume of the prostate is reduced by about 25%. It can be seen that the Chinese medicine composition of the present invention can effectively improve prostate hyperplasia.

[0081] Case 4

[0082] Li Fei, male, 48 years old, corporate executive, average workload, frequent social events, personal health attention, good friend of Case 3 Mr. Jin, two people have physical examinations together, and maintain health simultaneously. Physical examination in May 2018, prostate B-ultrasound showed prostate left and right diameter 4.1, front and back diameter 3.1, upper and lower diameter 3.0, echo distribution is uniform (such as Figure 7 The calculated prostate volume is approximately 38.13 cm 3 In March 2019, the maintenance was started, and comprehensive maintenance lasted for 3 months, during which the Chinese medicine composition prepared in Example 1 was taken for 1 month, and taken every day, 1 dose per day. In July 2019, the prostate ultrasound was reviewed, showing: the left and right diameter of the prostate was 3.7, the front and back diameter was 2.3, the upper and lower diameter was 2.5, and the echo distribution was uniform (such as Figure 8 The calculated prostate volume is approximately 21.28 cm 3 , the volume of the prostate is reduced by about 44%. It can be seen that the Chinese medicine composition of the present invention can effectively improve prostate hyperplasia.

[0083] Case 5

[0084] Peng*, male, 48 years old, a retired soldier, has been demobilized for many years and manages his daily living habits well. In the early days of military training, he was overloaded and damaged his kidneys, and had hematuria. Although he received timely treatment, he had no concept of recovery at that time and always had some symptoms in the urinary system. In September 2023, a physical examination showed that the prostate was enlarged, with a left-right diameter of 4.0, a superior-inferior diameter of 3.5, and an anteroposterior diameter of 4.3. The bilateral lobes were symmetrical, and strong echo spots were seen at the junction of the inner and outer glands (such as Fig. 9 The calculated prostate volume is approximately 60.2 cm 3 Immediately start maintenance, comprehensive maintenance for 6 months, at the same time take the Chinese medicine composition prepared in Example 1 for 1 month, take it every day, 1 dose per day, in March 2024, check the prostate B-ultrasound, showing: prostate volume increased, left and right diameter 4.4, upper and lower diameter 3.5, front and back diameter 3.4, bilateral lobes symmetrical (such as Fig.10 The calculated prostate volume is approximately 52.36 cm 3 , the volume of the prostate gland is reduced by about 13%. It can be seen that the Chinese medicine composition of the present invention can effectively improve prostate hyperplasia.

[0085] Case 6

[0086] Su*Sheng, male, 67 years old, retired cadre, overall physical condition is good, prostate problems are particularly prominent. In 2020, the physical examination showed that the prostate B-ultrasound showed that the prostate size was 60*55*48mm, the shape was normal, the internal echo was uniform, and no lesions were found (such as Fig.11 The calculated prostate volume is approximately 158.4 cm 3 In December 2021, prostate maintenance was initiated, and the Chinese medicine composition prepared in Example 1 was taken for 1 month, and taken every day, 1 dose per day. After review, B-ultrasound in January 2021 showed that the prostate size was 56*52*51mm (such as Fig.12 The calculated prostate volume is approximately 148.5 cm 3 The volume of the prostate gland was reduced by about 6%. The patient continued to take the Chinese medicine composition prepared in Example 1 for 2 months, taking it every day, 1 dose per day, for a total of 3 months of continuous medication. The B-ultrasound examination in March 2021 showed that the size of the prostate gland was 51*46*47 (as shown in Figure 1). Fig.13 The calculated prostate volume is approximately 110.3 cm 3The volume of the prostate was reduced by about 30% compared with that before the treatment. It can be seen that the Chinese medicine composition of the present invention can effectively improve prostate hyperplasia.

[0087] Case 7

[0088] Yang Bao, male, 54 years old, is a leader in office. He has many social gatherings and drinks a lot. He has prominent gastritis symptoms and esophageal reflux. In March 2019, the B-ultrasound showed that the prostate was about 4.0*3.5cm in size (the hospital B-ultrasound only measured two dimensions), slightly full in shape, with fine and uneven echoes in the parenchyma. Multiple strong echo spots can be seen in the parenchyma (such as Fig.14 As shown). While maintaining the gastrointestinal tract, the Chinese medicine composition prepared in Example 1 was taken to improve the prostate for 1 month, and it was taken every day, 1 dose per day. In December 2019, the physical examination showed that the size of the prostate was about 4.0*3.0cm (the hospital B-ultrasound only measured two dimensions) (as shown Fig.15 Compared with the prostate ultrasound data in March, it is reduced by 15%. It can be seen that the Chinese medicine composition of the present invention can effectively improve prostate hyperplasia.

[0089] Case 8

[0090] Ying Huan, male, 56 years old, entrepreneur, has many social events, controllable lifestyle, family hemolytic anemia gene, and injuries in various parts of the body. PET / CT in January 2019 showed: prostate volume increased, about 5.5*4.6cm, relatively uniform density, FDG metabolism was diffusely increased, SUVmax=2.89 (such as Fig.16 After 2 years of systematic maintenance, including taking the Chinese medicine composition prepared in Example 1 for 6 months, taking it every day, 1 dose per day, B-ultrasound in June 2021 showed: the left and right diameter of the prostate is about 4.3, the front and back diameter is about 2.8, the upper and lower diameter is about 2.9, the echo distribution is uniform, and multiple strong light spot echoes can be seen, one of which is about 0.6 cm in size, and there is a 0.4*0.4 cystic dark area in the prostate with clear boundaries (such as Fig.17 ). The detection equipment and measurement methods were different before and after the two tests, but it can be clearly seen that the prostate has shrunk by at least 50% after the maintenance, and the prostate is basically in line with the normal size, with only "partial diameter lines being larger". It can be seen that the Chinese medicine composition of the present invention can effectively improve prostate hyperplasia.

[0091] It can be seen from the above embodiments and experimental examples that the Chinese medicine composition of the present invention can significantly improve prostate hyperplasia, slow down further tissue damage and malignant transformation, and has a very high effectiveness.

[0092] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principle of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. A Chinese medicine composition for improving prostatic hyperplasia, characterized in that: The invention comprises the following ingredients in parts by weight: 15-25 parts of yam, 15-25 parts of smilax glabra, 15-25 parts of coix seeds, 10-20 parts of salvia miltiorrhiza, 10-20 parts of whole trichosanthes, 10-20 parts of corn silk, 5-15 parts of Morinda officinalis, 5-15 parts of Cistanche deserticola, 5-15 parts of Eucommia ulmoides, 5-15 parts of Imperata root, 5-15 parts of dandelion and 5-15 parts of cassia twig.

2. The Chinese medicine composition according to claim 1, characterized in that: The invention comprises the following ingredients in parts by weight: 18-22 parts of yam, 18-22 parts of smilax glabra, 18-22 parts of coix seeds, 12-18 parts of salvia miltiorrhiza, 12-18 parts of whole trichosanthes, 12-18 parts of corn silk, 7-14 parts of Morinda officinalis, 7-14 parts of Cistanche deserticola, 7-14 parts of Eucommia ulmoides, 7-14 parts of Imperata root, 7-14 parts of dandelion and 7-14 parts of cassia twig.

3. The Chinese medicine composition according to claim 1, characterized in that The invention comprises the following ingredients in parts by weight: 20 parts of yam, 20 parts of smilax glabra, 20 parts of coix seeds, 15 parts of salvia miltiorrhiza, 15 parts of whole trichosanthes, 15 parts of corn silk, 10 parts of Morinda officinalis, 10 parts of Cistanche deserticola, 10 parts of Eucommia ulmoides, 10 parts of Imperata root, 10 parts of dandelion and 10 parts of cassia twig.

4. The method for preparing the Chinese medicine composition according to any one of claims 1 to 3, characterized in that: The following steps are involved: 1) mixing the Chinese medicine and water 2 to 5 times the total weight of the Chinese medicine and soaking them, boiling them over high heat until the water boils, then switching to medium heat and continuing to boil for 10 to 30 minutes, filtering to obtain a filter residue and a first filtrate; 2) mixing the filter residue of step 1) with water in an amount of 1 to 3 times the total mass of the Chinese medicine, boiling over high heat until the water boils, then switching to medium heat and continuing to boil for 10 to 30 minutes, filtering to obtain a second filtrate; 3) Mixing the first filtrate and the second filtrate to obtain the Chinese medicine composition.

5. Use of the Chinese medicine composition according to any one of claims 1 to 3 or the Chinese medicine composition prepared by the preparation method according to claim 4 in the preparation of a drug for improving prostate hyperplasia.

6. The use according to claim 5, characterized in that: The dosage forms of the drug include powders, tablets, granules, capsules, solutions, emulsions, and suspensions.

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