Polydatin composition capable of whitening skin, removing freckles and removing yellowness and preparation method of polydatin composition

Abstract

The invention discloses a polydatin composition with whitening, freckle removing and yellowing removing effects and a preparation method of the polydatin composition. The composition is prepared from polydatin powder, glycerin, ascorbic acid, butanediol, butyl resorcinol, nicotinamide, fatty alcohol-polyoxyethylene ether and water. The whitening and freckle-removing mask can effectively improve the whitening, freckle-removing and yellow-removing effects, and has the effects of inhibiting melanin precipitation such as dark skin and uneven skin color, and promoting melanin shedding.

Description

Technical Field

[0001] The invention relates to the field of skin care, and in particular to a polydatin composition capable of whitening, removing spots and yellowing, and a preparation method thereof. Background Art

[0002] Polygonum cuspidatum is also a traditional Chinese medicinal material. Polygonum cuspidatum has the effects of clearing away heat and detoxifying, promoting blood circulation and removing blood stasis. The main components include diphenylethylene, anthraquinones, flavonoids, phenols, etc. Polydatin is an extract of the plant Polygonum cuspidatum, which can be used for antitussive, regulating blood lipids, lowering cholesterol, and anti-shock. Polydatin is the product of the combination of resveratrol and glucose, also known as resveratrol glycosides, and its pharmacological action is similar to resveratrol. Both can be converted in the body. Polydatin has antifungal and antibacterial activity, and has a significant inhibitory effect on Staphylococcus aureus and Pneumococcus. The existing polydatin is used in the field of skin care to improve the skin care effect of skin care products. The extraction and application of polydatin is a technical problem that needs to be solved at present. For this reason, the present invention proposes a composition of polydatin with whitening, freckle removal and yellowing and a preparation method thereof. Summary of the invention

[0003] In view of the above problems, the present invention proposes a composition of polydatin with whitening, freckle removal and yellowing effect and a preparation method thereof.

[0004] In order to achieve the above-mentioned purpose, the present invention adopts the following technical solutions:

[0005] A polydatin composition having the effects of whitening, removing spots and yellowing, the composition is prepared from the following raw materials in parts by weight:

[0006] Polydatin powder 8-13 parts;

[0007] 4-8 parts of glycerol;

[0008] Ascorbic acid 2-4.5 parts;

[0009] 3-5 parts of butanediol;

[0010] 2-5 parts of butylresorcinol;

[0011] Niacinamide 0.5-1 part;

[0012] Fatty alcohol polyoxyethylene ether 0.2-1 part;

[0013] 5-9 parts water.

[0014] Wherein, the preparation and extraction method of the polydatin powder comprises the following steps:

[0015] S1, after crushing and grinding the knotweed, add ethanol solution, place it under ultrasound for 45-60min, and then perform reflux extraction 3-5 times, after each reflux extraction, apply ultrasound with a power of 150-300W for 10-15min, and the mass of ethanol solution added for each reflux extraction is 8-10 times the mass of the knotweed raw material;

[0016] S2, adding activated carbon to the reflux liquid obtained by reflux extraction, filtering it and then passing it through a specific concentration process to obtain a concentrated liquid;

[0017] S3, add 2-3 times the mass of silica gel particles with a diameter of 45-55 μm and a temperature of 65-75°C to the concentrated solution, then mix and stir, apply ultrasound for 10-20 minutes with a power of 150-300W, then mix again, place in an oven at 45-50°C and dry for 4-5 hours to obtain a silica gel particle intermediate;

[0018] S4, placing the silica gel particle intermediate in a chromatography column, using a medium pressure chromatography column for sample loading and elution, and collecting the eluate;

[0019] S5, the eluate is concentrated by reduced pressure evaporation under vacuum, the evaporation temperature is controlled at 50-55° C., the air pressure is controlled at 0.025-0.04 MPa, and the volume is concentrated to 1 / 18-1 / 15 of the original volume to obtain a concentrated viscous solution;

[0020] S6, cooling the concentrated viscous solution at -15°C to fully crystallize, and finally filtering and drying to obtain the polydatin powder.

[0021] Preferably, the specific steps of the concentration process include:

[0022] (1) Concentrating the reflux liquid by vacuum evaporation and introducing argon protective gas, controlling the heating temperature at 75-85° C. and the gas pressure at 0.045-0.06 MPa, and concentrating the reflux liquid to 1 / 5-1 / 3 of the original volume;

[0023] (2) Continue to evaporate the above concentrated solution under reduced pressure, lower the concentration temperature to 65-75° C., lower the concentration pressure to 0.03-0.04 MPa, and concentrate to 1 / 15-1 / 10 of the initial reflux volume to obtain the above concentrated solution.

[0024] Preferably, the composition is made from the following raw materials in parts by weight:

[0025] Polydatin powder 10-11 parts;

[0026] Glycerin 5-7 parts;

[0027] Ascorbic acid 2.5-4 parts;

[0028] 3-4 parts of butanediol;

[0029] 2-4 parts of butylresorcinol;

[0030] Niacinamide 0.6-0.8 parts;

[0031] Fatty alcohol polyoxyethylene ether 0.4-0.7;

[0032] 6-8 parts water

[0033] Preferably, the composition is made from the following raw materials in parts by weight:

[0034] Polydatin powder 10.5 parts;

[0035] 6 parts of glycerol;

[0036] 3 parts of ascorbic acid;

[0037] 3.5 parts of butanediol;

[0038] 3 parts of butylresorcinol;

[0039] Niacinamide 0.7 parts;

[0040] Fatty alcohol polyoxyethylene ether 0.5;

[0041] 7 parts water.

[0042] Preferably, the preparation method of the polydatin composition with whitening, freckle removal and yellowing effect is to mix polydatin powder, glycerin, ascorbic acid, butylene glycol, butylresorcinol, niacinamide and fatty alcohol polyoxyethylene ether in a high-speed stirrer, fully mix them under ultrasound at 1000-1200 rpm and a power of 200 W, dry them into powder, and discharge the materials to obtain the composition.

[0043] Preferably, the application of the polydatin composition having the effects of whitening, removing spots and yellowing is added to skin care products.

[0044] Preferably, the skin care products include facial cream, facial mask liquid, and essence liquid.

[0045] Preferably, the added mass of the composition is 11.5-14% of the mass of the skin care product.

[0046] Preferably, the added mass of the composition is 12.5% ​​of the mass of the skin care product.

[0047] Due to the adoption of the above technical solution, the beneficial effects of the present invention are:

[0048] The present invention provides a composition for facial cream, facial mask liquid and essence liquid, which can effectively improve the effect of whitening, removing freckles and yellowing, inhibit melanin precipitation such as dull skin and uneven skin color, and promote melanin shedding; the present invention also provides a facial cream with a composition of polydatin for whitening, removing freckles and yellowing, etc. DETAILED DESCRIPTION

[0049] To make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the technical solution in the embodiments of the present invention will be clearly and completely described below in combination with the embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0050] Embodiment 1:

[0051] The present embodiment prepares the polydatin composition with whitening, freckle removal and yellowing effect, which is made of the following raw materials in parts by weight:

[0052] Polydatin powder 10.5 parts;

[0053] 6 parts of glycerol;

[0054] 3 parts of ascorbic acid;

[0055] 3.5 parts of butanediol;

[0056] 3 parts of butylresorcinol;

[0057] Niacinamide 0.7 parts;

[0058] Fatty alcohol polyoxyethylene ether 0.5;

[0059] 7 parts water.

[0060] The preparation and extraction method of polydatin powder comprises the following steps:

[0061] S1, after crushing and grinding the knotweed, add ethanol solution, place it under ultrasound for 50 minutes, and then perform reflux extraction 5 times, after each reflux extraction, apply ultrasound with a power of 200W for 10-15 minutes, and the mass of ethanol solution added for each reflux extraction is 9 times the mass of the knotweed raw material;

[0062] S2, adding activated carbon to the reflux liquid obtained by reflux extraction, filtering it and then passing it through a specific concentration process to obtain a concentrated liquid;

[0063] The specific steps of the concentration process include:

[0064] (1) Concentrating the reflux liquid by vacuum evaporation, introducing argon protective gas, controlling the heating temperature at 80° C. and the gas pressure at 0.05 MPa, and concentrating the reflux liquid to 4 / 15 of its original volume;

[0065] (2) Continue to evaporate the above concentrated solution under reduced pressure, lower the concentration temperature to 65-75° C., lower the concentration pressure to 0.035 MPa, and concentrate to 2 / 9 of the initial reflux volume to obtain a concentrated solution.

[0066] S3, add 2.5 times the mass of silica gel particles with a diameter of 50 μm and a temperature of 70°C to the concentrated solution, then mix and stir, apply ultrasound with a power of 250W for 15 minutes, then mix again, place in an oven at 47°C and dry for 4.5 hours to obtain a silica gel particle intermediate;

[0067] S4, placing the silica gel particle intermediate in a chromatography column, using a medium pressure chromatography column for sample loading and elution, and collecting the eluate;

[0068] S5, the eluate is concentrated by reduced pressure evaporation under vacuum environment, the evaporation temperature is controlled at 52° C., the gas pressure is controlled at 0.035 MPa, and the eluate is concentrated to 1 / 18 of the original volume to obtain a concentrated viscous solution;

[0069] S6. Cool the concentrated viscous solution at -15°C to fully crystallize, and finally filter and dry to obtain polydatin powder.

[0070] The method for preparing the polydatin composition having the function of whitening, removing spots and yellowing in this embodiment is as follows:

[0071] First, polydatin powder, glycerol, ascorbic acid, butylene glycol, butylresorcinol, nicotinamide, and fatty alcohol polyoxyethylene ether are mixed in a high-speed stirrer, and fully mixed under ultrasound at a stirring speed of 1100 rpm and a power of 200 W. Stir for 17 minutes to mix the materials, and then dry them into powder to obtain the composition.

[0072] Embodiment 2:

[0073] The present embodiment prepares the polydatin composition with whitening, freckle removal and yellowing effect, which is made of the following raw materials in parts by weight:

[0074] Polydatin powder 10 parts;

[0075] Glycerin 5 parts;

[0076] 2 parts ascorbic acid;

[0077] 3 parts of butanediol;

[0078] 2 parts of butylresorcinol;

[0079] Niacinamide 0.6 parts;

[0080] Fatty alcohol polyoxyethylene ether 0.4;

[0081] 6 parts water.

[0082] The preparation and extraction method of polydatin powder comprises the following steps:

[0083] S1, after crushing and grinding the knotweed, add ethanol solution, place it under ultrasound for 55min, and then perform reflux extraction 4 times. After each reflux extraction, ultrasound with a power of 250W is applied for 13min. The mass of ethanol solution added for each reflux extraction is 8 times the mass of the knotweed raw material;

[0084] S2, adding activated carbon to the reflux liquid obtained by reflux extraction, filtering it and then passing it through a specific concentration process to obtain a concentrated liquid;

[0085] The specific steps of the concentration process include:

[0086] (1) Concentrating the reflux liquid by vacuum evaporation, introducing argon protective gas, controlling the heating temperature at 75° C. and the gas pressure at 0.045 MPa, and concentrating the reflux liquid to 1 / 5 of its original volume;

[0087] (2) Continue to evaporate the above concentrated solution under reduced pressure, lower the concentration temperature to 75° C., lower the concentration pressure to 0.04 MPa, and concentrate to 1 / 10 of the initial reflux volume to obtain a concentrated solution.

[0088] S3, add 3 times the mass of silica gel particles with a diameter of 55 μm and a temperature of 75°C to the concentrated solution, then mix and stir, apply ultrasound with a power of 300W for 0 min, then mix again, place in an oven at 45°C and dry for 5 hours to obtain a silica gel particle intermediate;

[0089] S4, placing the silica gel particle intermediate in a chromatography column, using a medium pressure chromatography column for sample loading and elution, and collecting the eluate;

[0090] S5, the eluate is concentrated by reduced pressure evaporation under vacuum environment, the evaporation temperature is controlled at 55° C., the gas pressure is controlled at 0.025 MPa, and the volume is concentrated to 1 / 15 of the original volume to obtain a concentrated viscous solution;

[0091] S6. Cool the concentrated viscous solution at -15°C to fully crystallize, and finally filter and dry to obtain polydatin powder.

[0092] The method for preparing the polydatin composition having the function of whitening, removing spots and yellowing in this embodiment is as follows:

[0093] First, polydatin powder, glycerol, ascorbic acid, butylene glycol, butylresorcinol, nicotinamide, and fatty alcohol polyoxyethylene ether are mixed in a high-speed stirrer, and fully mixed under ultrasound at a stirring speed of 1200 rpm and a power of 200 W. The mixture is stirred for 20 minutes to mix the materials, and then dried to form a powder, and the composition is obtained by discharging the material.

[0094] Embodiment 3:

[0095] The present embodiment prepares the polydatin composition with whitening, freckle removal and yellowing effect, which is made of the following raw materials in parts by weight:

[0096] Polydatin powder 11 parts;

[0097] Glycerin 7 parts;

[0098] 4.5 parts of ascorbic acid;

[0099] 4 parts of butanediol;

[0100] 4 parts of butylresorcinol;

[0101] Niacinamide 0.8 parts;

[0102] Fatty alcohol polyoxyethylene ether 0.7;

[0103] 8 parts water.

[0104] The preparation and extraction method of polydatin powder comprises the following steps:

[0105] S1, after crushing and grinding the knotweed, add ethanol solution, place it under ultrasound for 45min, and then perform reflux extraction for 3-5 times, after each reflux extraction, apply ultrasound with a power of 150W for 10min, and the mass of ethanol solution added for each reflux extraction is 8 times the mass of the knotweed raw material;

[0106] S2, adding activated carbon to the reflux liquid obtained by reflux extraction, filtering it and then passing it through a specific concentration process to obtain a concentrated liquid;

[0107] The specific steps of the concentration process include:

[0108] (1) Concentrating the reflux liquid by vacuum evaporation, introducing argon protective gas, controlling the heating temperature at 75° C. and the gas pressure at 0.045 MPa, and concentrating the reflux liquid to 1 / 5 of its original volume;

[0109] (2) Continue to evaporate the above concentrated solution under reduced pressure, lower the concentration temperature to 65° C., lower the concentration pressure to 0.03 MPa, and concentrate to 1 / 15 of the initial reflux volume to obtain a concentrated solution.

[0110] S3, add 2 times the mass of silica gel particles with a diameter of 45 μm and a temperature of 65°C to the concentrated solution, then mix and stir, apply ultrasound with a power of 150W for 10 minutes, then mix again, place in a 45°C oven and dry for 4 hours to obtain a silica gel particle intermediate;

[0111] S4, placing the silica gel particle intermediate in a chromatography column, using a medium pressure chromatography column for sample loading and elution, and collecting the eluate;

[0112] S5, the eluate is concentrated by reduced pressure evaporation under vacuum environment, the evaporation temperature is controlled at 50° C., the gas pressure is controlled at 0.025 MPa, and the eluate is concentrated to 1 / 18 of the original volume to obtain a concentrated viscous solution;

[0113] S6. Cool the concentrated viscous solution at -15°C to fully crystallize, and finally filter and dry to obtain polydatin powder.

[0114] The method for preparing the polydatin composition having the function of whitening, removing spots and yellowing in this embodiment is as follows:

[0115] First, polydatin powder, glycerol, ascorbic acid, butylene glycol, butylresorcinol, nicotinamide, and fatty alcohol polyoxyethylene ether are mixed in a high-speed stirrer, and fully mixed under ultrasound at a stirring speed of 1000 rpm and a power of 200 W. Stir for 20 minutes to mix the materials, and then dry them into powder to obtain a composition.

[0116] Embodiment 4:

[0117] The present embodiment prepares the polydatin composition with whitening, freckle removal and yellowing effect, which is made of the following raw materials in parts by weight:

[0118] Polydatin powder 13 parts;

[0119] 8 parts of glycerol;

[0120] 2.5 parts of ascorbic acid;

[0121] Butanediol 5 parts;

[0122] 5 parts of butylresorcinol;

[0123] 1 part of niacinamide;

[0124] 1 part of fatty alcohol polyoxyethylene ether;

[0125] 9 parts water.

[0126] The preparation and extraction method of polydatin powder comprises the following steps:

[0127] S1, after crushing and grinding the knotweed, add ethanol solution, place it under ultrasound for 55 minutes, and then perform 5 reflux extractions, after each reflux extraction, apply ultrasound with a power of 200W for 10-15 minutes, and the mass of ethanol solution added for each reflux extraction is 9 times the mass of the knotweed raw material;

[0128] S2, adding activated carbon to the reflux liquid obtained by reflux extraction, filtering it and then passing it through a specific concentration process to obtain a concentrated liquid;

[0129] The specific steps of the concentration process include:

[0130] (1) Concentrating the reflux liquid by vacuum evaporation and introducing argon protective gas, with the heating temperature controlled at 82° C. and the gas pressure controlled at 0.055 MPa, and concentrating the reflux liquid to 1 / 3 of its original volume;

[0131] (2) Continue to evaporate the above concentrated solution under reduced pressure, lower the concentration temperature to 71° C., lower the concentration pressure to 0.03 MPa, and concentrate to 1 / 10 of the initial reflux volume to obtain a concentrated solution.

[0132] S3, add 3 times the mass of silica gel particles with a diameter of 55 μm and a temperature of 68°C to the concentrated solution, then mix and stir, apply ultrasound with a power of 250W for 14 minutes, then mix again, place in an oven at 51°C and dry for 5 hours to obtain a silica gel particle intermediate;

[0133] S4, placing the silica gel particle intermediate in a chromatography column, using a medium pressure chromatography column for sample loading and elution, and collecting the eluate;

[0134] S5, the eluate is concentrated by reduced pressure evaporation under vacuum environment, the evaporation temperature is controlled at 52° C., the gas pressure is controlled at 0.038 MPa, and the eluate is concentrated to 1 / 15 of the original volume to obtain a concentrated viscous solution;

[0135] S6. Cool the concentrated viscous solution at -15°C to fully crystallize, and finally filter and dry to obtain polydatin powder.

[0136] The method for preparing the polydatin composition having the function of whitening, removing spots and yellowing in this embodiment is as follows:

[0137] First, polydatin powder, glycerol, ascorbic acid, butylene glycol, butylresorcinol, nicotinamide, and fatty alcohol polyoxyethylene ether are mixed in a high-speed stirrer, and fully mixed under ultrasound at a stirring speed of 1200 rpm and a power of 200 W. The mixture is stirred for 20 minutes to mix the materials, and then dried to form a powder, and the composition is obtained by discharging the material.

[0138] Embodiment 5:

[0139] The present embodiment prepares the polydatin composition with whitening, freckle removal and yellowing effect, which is made of the following raw materials in parts by weight:

[0140] Polydatin powder 8 parts;

[0141] 4 parts of glycerol;

[0142] 4 parts of ascorbic acid;

[0143] 3 parts of butanediol;

[0144] 2 parts of butylresorcinol;

[0145] 0.5 parts of niacinamide;

[0146] 0.2 parts of fatty alcohol polyoxyethylene ether;

[0147] 5 parts water.

[0148] The preparation and extraction method of polydatin powder comprises the following steps:

[0149] S1, after crushing and grinding the knotweed, add ethanol solution, place it under ultrasound for 50 minutes, and then perform reflux extraction 4 times. After each reflux extraction, ultrasound with a power of 300W is applied for 12 minutes. The mass of ethanol solution added for each reflux extraction is 10 times the mass of the knotweed raw material;

[0150] S2, adding activated carbon to the reflux liquid obtained by reflux extraction, filtering it and then passing it through a specific concentration process to obtain a concentrated liquid;

[0151] The specific steps of the concentration process include:

[0152] (1) Concentrating the reflux liquid by vacuum evaporation, introducing argon protective gas, controlling the heating temperature at 85° C. and the gas pressure at 0.06 MPa, and concentrating the reflux liquid to 1 / 5 of its original volume;

[0153] (2) Continue to evaporate the above concentrated solution under reduced pressure, lower the concentration temperature to 75° C., lower the concentration pressure to 0.03 MPa, and concentrate to 1 / 15 of the initial reflux volume to obtain a concentrated solution.

[0154] S3, add 2-3 times the mass of silica gel particles with a diameter of 45 μm and a temperature of 75°C to the concentrated solution, then mix and stir, apply ultrasound for 20 minutes with a power of 300 W, then mix again, place in an oven at 50°C and dry for 5 hours to obtain a silica gel particle intermediate;

[0155] S4, placing the silica gel particle intermediate in a chromatography column, using a medium pressure chromatography column for sample loading and elution, and collecting the eluate;

[0156] S5, the eluate is concentrated by reduced pressure evaporation under vacuum, the evaporation temperature is controlled at 50° C., the gas pressure is controlled at 0.035 MPa, and the eluate is concentrated to 1 / 15 of the original volume to obtain a concentrated viscous solution;

[0157] S6. Cool the concentrated viscous solution at -15°C to fully crystallize, and finally filter and dry to obtain polydatin powder.

[0158] The method for preparing the polydatin composition having the function of whitening, removing spots and yellowing in this embodiment is as follows:

[0159] First, polydatin powder, glycerol, ascorbic acid, butylene glycol, butylresorcinol, nicotinamide, and fatty alcohol polyoxyethylene ether are mixed in a high-speed stirrer, and fully mixed under ultrasound at a stirring speed of 1100 rpm and a power of 200 W, and stirred for 18 minutes to mix the materials. After drying, the materials are made into powder, and the composite is obtained by discharging the materials.

[0160] Embodiment 6:

[0161] In this example, the composition of polydatin with whitening, freckle removal and yellowing properties prepared in Example 1 was used to prepare a facial cream.

[0162] The cream is made of the following raw materials in percentage by weight:

[0163] The composition prepared in Example 1 11.5%;

[0164] Oil phase: polydimethylsiloxane 1%, vaseline 2%, emulsifier 0.65%;

[0165] Aqueous phase: propylene glycol 2%, glycerol 1%, glycerin 3%, hyaluronic acid 1.2%, balance water;

[0166] The specific preparation steps for preparing the facial cream are as follows:

[0167] (1) placing the oil phase raw materials in a high-speed stirrer, mixing and stirring at a stirring speed of 800 rpm for 10 min to obtain an oil phase liquid;

[0168] (2) After adding the aqueous phase raw materials into a high-speed stirrer and mixing, the aqueous phase raw materials are added into the oil phase liquid and mixed thoroughly, and then the composition is added. The stirring speed is adjusted to 1300 rpm, and 100 W ultrasound is applied for stirring. After stirring for 25 minutes, the raw materials are discharged to obtain a facial cream.

[0169] Embodiment 7:

[0170] In this example, the composition of polydatin with whitening, freckle removal and yellowing properties prepared in Example 1 was used to prepare a facial cream.

[0171] The cream is made of the following raw materials in percentage by weight:

[0172] The composition prepared in Example 1 12.5%;

[0173] Oil phase: polydimethylsiloxane 1%, vaseline 2%, emulsifier 0.65%;

[0174] Aqueous phase: propylene glycol 2%, glycerol 1%, glycerin 3%, hyaluronic acid 1.2%, balance water;

[0175] The specific preparation steps for preparing the facial cream are as follows:

[0176] (1) placing the oil phase raw materials in a high-speed stirrer, mixing and stirring at a stirring speed of 800 rpm for 10 min to obtain an oil phase liquid;

[0177] (2) After adding the aqueous phase raw materials into a high-speed stirrer and mixing, the aqueous phase raw materials are added into the oil phase liquid and mixed thoroughly, and then the composition is added. The stirring speed is adjusted to 1300 rpm, and 100 W ultrasound is applied for stirring. After stirring for 25 minutes, the raw materials are discharged to obtain a facial cream.

[0178] Embodiment 8:

[0179] In this example, the composition of polydatin with whitening, freckle removal and yellowing properties prepared in Example 1 was used to prepare a facial cream.

[0180] The cream is made of the following raw materials in percentage by weight:

[0181] The composition prepared in Example 1 14%;

[0182] Oil phase: polydimethylsiloxane 1%, vaseline 2%, emulsifier 0.65%;

[0183] Aqueous phase: propylene glycol 2%, glycerol 1%, glycerin 3%, hyaluronic acid 1.2%, balance water;

[0184] The specific preparation steps for preparing the facial cream are as follows:

[0185] (1) placing the oil phase raw materials in a high-speed stirrer, mixing and stirring at a stirring speed of 800 rpm for 10 min to obtain an oil phase liquid;

[0186] (2) After adding the aqueous phase raw materials into a high-speed stirrer and mixing, the aqueous phase raw materials are added into the oil phase liquid and mixed thoroughly, and then the composition is added. The stirring speed is adjusted to 1300 rpm, and 100 W ultrasound is applied for stirring. After stirring for 25 minutes, the raw materials are discharged to obtain a facial cream.

[0187] Comparative Example 1:

[0188] In this comparative example 1, the composition of polydatin having whitening, freckle-removing and yellowing properties prepared in Example 1 was used to prepare a facial cream.

[0189] The facial cream of this comparative example is made of the following raw materials in percentage by mass:

[0190] Oil phase: polydimethylsiloxane 1%, vaseline 2%, emulsifier 0.65%;

[0191] Aqueous phase: propylene glycol 2%, glycerol 1%, glycerin 3%, hyaluronic acid 1.2%, balance water;

[0192] The specific preparation steps for preparing the facial cream are as follows:

[0193] (1) placing the oil phase raw materials in a high-speed stirrer, mixing and stirring at a stirring speed of 800 rpm for 10 min to obtain an oil phase liquid;

[0194] (2) After adding the aqueous phase raw materials into a high-speed stirrer and mixing, the stirring speed was adjusted to 1300 rpm, and 100 W of ultrasound was applied for stirring. After stirring for 25 minutes, the material was discharged to obtain a facial cream.

[0195] Cream effect evaluation:

[0196] The testing standards are mainly based on QB / T1857-2013 for moisturizing creams and GB / T13531.1-2008 General Testing Methods for Cosmetics

[0197] Among them, the sensory indicators (color, aroma, structure) meet the industry regulations, and the physical and chemical indicators (pH, heat resistance, cold resistance, active ingredients) meet the industry regulations.

[0198] Volunteers with yellow spots on the face, no acne and obvious wounds, and no history of skin allergies were selected. The volunteers were aged 25-40 years old and divided into 5 groups, namely, Example 6-8 groups, a comparative group, and a common group using commercially available facial cream, with 20 people in each group;

[0199] Apply the cream evenly on the cheeks and forehead of the volunteers in equal amounts and areas;

[0200] Among them, the area of ​​the cheek and forehead is (2cm×2cm), and the mass of the cream used is 0.5g;

[0201] The frequency of application is once every day between 7:00-8:00 in the morning and 19:00-20:00 in the afternoon for 5 consecutive weeks.

[0202] The whitening and brightening effects of the cream were rated by volunteers.

[0203] The specific scoring criteria are:

[0204] Grade A: 10-8 points: skin brightening and whitening effects are obvious, and skin condition is significantly improved;

[0205] Grade B: 7-6 points: The skin lightening and whitening effect is good, and the skin is improved to a certain extent;

[0206] C level 5-3 points: The skin lightening and whitening effect is subtle, and the skin has improved to a certain extent

[0207] Grade D is 1-2 points: no effect, no improvement.

[0208] Grade E: 0 points: side effects (such as redness, swelling, itching, acne, etc.).

[0209] The effect scores after use were counted from a total of 100 volunteers.

[0210]

[0211] Based on the above, we can get:

[0212] (1) This cream has a good whitening effect and can brighten the user's skin tone;

[0213] (2) In Examples 6-7, when the amount of the composition used accounts for 12.5% ​​of the mass of the cream, the cream has a better whitening effect.

[0214] The usage effects are as follows:

[0215]

[0216] Based on the above, we can get:

[0217] (1) Examples 6-7 have good freckle and yellowing removal effects;

[0218] (2) In Examples 6-8, when the amount of the composition used accounts for 12.5% ​​of the mass of the cream, the cream has a better effect of removing spots and yellowing, and the cream of this embodiment is better than the existing commercially available cream;

[0219] (3) When the removal composition is added to the cream of this embodiment, the overall performance of the cream decreases, indicating that the composition plays a major role in whitening, removing spots and yellowing.

[0220] Embodiment 9:

[0221] In this example, the composition of polydatin with whitening, freckle-removing and yellowing properties prepared in Example 1 was used to prepare an essence.

[0222] The essence is made of the following raw materials in percentage by weight:

[0223] The composition prepared in Example 1 includes 11.5%, propylene glycol 1.5%, glycerin 1.1%, glycerol 0.5%, hyaluronic acid 0.56%, carbomer 0.12%, disodium EDTA 0.015%, vaseline 0.2%, sodium polyacrylate 0.12%, tocopherol 0.01%, skin repair agent 0.01%, activated carbon 0.08%, and the balance water.

[0224] The specific preparation steps for preparing the essence are as follows: mixing the raw materials in a high-speed stirrer, controlling the stirring speed to 1000 rpm, stirring for 5 minutes, and discharging the materials to obtain the essence of Example 9.

[0225] Comparative Example 2:

[0226] In this comparative example 2, the composition of polydatin having whitening, freckle-removing and yellowing properties prepared in Example 1 was used to prepare an essence.

[0227] The essence is made of the following raw materials in percentage by weight:

[0228] Propylene glycol 1.5%, glycerin 1.1%, glycerol 0.5%, hyaluronic acid 0.56%, carbomer 0.12%, disodium EDTA 0.015%, petrolatum 0.2%, sodium polyacrylate 0.12%, tocopherol 0.01%, skin repair agent 0.01%, activated carbon 0.08%, balance water.

[0229] The specific preparation steps for preparing the essence are as follows: mixing the raw materials in a high-speed stirrer, controlling the stirring speed to 1000 rpm, stirring for 5 minutes, and discharging the material to obtain the essence of this comparative example 2

[0230] Essence effect evaluation:

[0231] 60 volunteers with dark facial complexion were selected and divided into three groups, each with 20 people aged 25-40 years old, without skin allergies, etc., and the essences prepared in the present embodiment and the comparative example were used respectively. The melanin and color difference data were collected and analyzed for their facial skin, and the data were used as the skin background value. The volunteers used the essences once a day in the morning and evening for four consecutive weeks. The changes in skin whiteness and skin melanin MI value content before and after the essence were determined to determine the whitening effect of the cosmetics.

[0232]

[0233] Based on the above, it can be concluded that this essence has obvious whitening and anti-yellowing effects and can effectively reduce the melanin value of the skin.

[0234] The above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit the same. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that the technical solutions described in the aforementioned embodiments may still be modified, or some of the technical features may be replaced by equivalents. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the embodiments of the present invention.

[0235] This article uses specific examples to illustrate the principles and implementation methods of the present invention. The above examples are only used to help understand the methods and core ideas of the present invention. The above is only a preferred implementation of the present invention. It should be pointed out that due to the limitations of textual expression and the objective existence of infinite specific structures, ordinary technicians in this technical field can make several improvements, modifications or changes without departing from the principles of the present invention, and can also combine the above technical features in an appropriate manner; these improvements, modifications, changes or combinations, or the direct application of the inventive concept and technical solution to other occasions without improvement, should be regarded as the protection scope of the present invention.

Claims

1. A polydatin composition having whitening, freckle removal and yellowing effects, characterized in that: The composition is made from the following raw materials in parts by weight: Polydatin powder 8-13 parts; 4-8 parts of glycerol; Ascorbic acid 2-4.5 parts; 3-5 parts of butanediol; 2-5 parts of butylresorcinol; Niacinamide 0.5-1 part; Fatty alcohol polyoxyethylene ether 0.2-1 part; 5-9 parts water. Wherein, the preparation and extraction method of the polydatin powder comprises the following steps: S1, after crushing and grinding the knotweed, add ethanol solution, place it under ultrasound for 45-60min, and then perform reflux extraction 3-5 times, after each reflux extraction, apply ultrasound with a power of 150-300W for 10-15min, and the mass of ethanol solution added for each reflux extraction is 8-10 times the mass of the knotweed raw material; S2, adding activated carbon to the reflux liquid obtained by reflux extraction, filtering it and then passing it through a specific concentration process to obtain a concentrated liquid; S3, add 2-3 times the mass of silica gel particles with a diameter of 45-55 μm and a temperature of 65-75°C to the concentrated solution, then mix and stir, apply ultrasound for 10-20 minutes with a power of 150-300W, then mix again, place in an oven at 45-50°C and dry for 4-5 hours to obtain a silica gel particle intermediate; S4, placing the silica gel particle intermediate in a chromatography column, using a medium pressure chromatography column for sample loading and elution, and collecting the eluate; S5, the eluate is concentrated by reduced pressure evaporation under vacuum, the evaporation temperature is controlled at 50-55° C., the air pressure is controlled at 0.025-0.04 MPa, and the volume is concentrated to 1 / 18-1 / 15 of the original volume to obtain a concentrated viscous solution; S6, cooling the concentrated viscous solution at -15°C to fully crystallize, and finally filtering and drying to obtain the polydatin powder.

2. The polydatin composition having whitening, freckle removal and yellowing effects according to claim 1, characterized in that: The specific steps of the concentration process include: (1) Concentrating the reflux liquid by vacuum evaporation and introducing argon protective gas, controlling the heating temperature at 75-85° C. and the gas pressure at 0.045-0.06 MPa, and concentrating the reflux liquid to 1 / 5-1 / 3 of the original volume; (2) Continue to evaporate the above concentrated solution under reduced pressure, lower the concentration temperature to 65-75° C., lower the concentration pressure to 0.03-0.04 MPa, and concentrate to 1 / 15-1 / 10 of the initial reflux volume to obtain the above concentrated solution.

3. The polydatin composition having whitening, freckle removal and yellowing effects according to claim 1, characterized in that: The composition is made from the following raw materials in parts by weight: Polydatin powder 10-11 parts; Glycerin 5-7 parts; Ascorbic acid 2.5-4 parts; 3-4 parts of butanediol; 2-4 parts of butylresorcinol; Niacinamide 0.6-0.8 parts; Fatty alcohol polyoxyethylene ether 0.4-0.7; 6-8 parts water 4. The polydatin composition having whitening, freckle removal and yellowing effects according to claim 3, characterized in that: The composition is made from the following raw materials in parts by weight: Polydatin powder 10.5 parts; 6 parts of glycerol; 3 parts of ascorbic acid; 3.5 parts of butanediol; 3 parts of butylresorcinol; Niacinamide 0.7 parts; Fatty alcohol polyoxyethylene ether 0.5; 7 parts water.

5. A method for preparing a polydatin composition having whitening, freckle removal and yellowing effects as claimed in any one of claims 1 to 4, characterized in that: Polydatin powder, glycerol, ascorbic acid, butylene glycol, butylresorcinol, nicotinamide and fatty alcohol polyoxyethylene ether are mixed in a high-speed stirrer, fully mixed under ultrasound at 1000-1200 rpm and a power of 200 W, dried to form powder, and the composition is obtained by discharging the mixture.

6. An application of a polydatin composition having whitening, freckle removal and yellowing properties as claimed in any one of claims 1 to 4, characterized in that: The whitening, freckle-removing and yellowing-removing polygonum datum glycoside composition is added into skin care products.

7. The use of the polydatin composition having whitening, freckle removal and yellowing effects according to claim 6, characterized in that: The skin care products include facial cream, facial mask liquid and essence liquid.

8. The use of the polydatin composition having whitening, freckle removal and yellowing effects according to claim 6, characterized in that: The added mass of the composition is 11.5-14% of the mass of the skin care product.

9. The use of the polydatin composition having whitening, freckle removal and yellowing effects according to claim 8, characterized in that: The added mass of the composition is 12.5% ​​of the mass of the skin care product.

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