Hawthorn processing technology optimization method

The hawthorn preparation process is optimized through thermal analysis technology and high-performance liquid chromatography combined with hierarchical analysis method, which solves the problem of lack of scientific data in the traditional hawthorn preparation process, and achieves the stability of the medicinal ingredients and the improvement of the quality of traditional Chinese medicine preparations.

CN120594698APending Publication Date: 2025-09-05SHANXI UNIV OF CHINESE MEDICINE
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Patent Information

Application Number
CN202510692597.9
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-05-27
Publication Date
2025-09-05

AI Technical Summary

Technical Problem

The traditional hawthorn preparation process lacks scientific data support, resulting in inaccurate endpoints of preparation, affecting the stable performance of drug efficacy and the application of modern Chinese medicine preparations.

Method used

The main medicinal components of hawthorn were analyzed by thermal analysis technology and high-performance liquid chromatography. The hierarchical analysis method and AHP-CRITIC comprehensive weighting method were combined to optimize the preparation process parameters, and the optimal preparation temperature and time were determined through the response surface method.

Benefits of technology

It provides a scientific method of optimizing hawthorn preparation process to ensure the stability of the medicinal ingredients and the quality of traditional Chinese medicine preparations, and improves clinical efficacy.

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Abstract

The invention relates to the field of traditional Chinese medicines, in particular to a hawthorn processing technology optimization method, which adopts a thermal analysis technology and a high performance liquid chromatography method to systematically analyze the influence of different processing technologies on the contents of main medicinal components of hawthorn. According to the method, an analytic hierarchy process and an evaluation method (AHP-CRITIC) are used for comprehensive weighting, processing parameters are optimized in combination with a response surface method, the quality change in the hawthorn processing process can be effectively analyzed through combination of a thermal analysis technology and an HPLC method, and scientific methodological reference is provided for optimization of the processing technology through combined application of the AHP-CRITIC method and the response surface method.
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