Tamsulosin tablets

A kind of technology of tamsulosin and tablet, applied in the unit dosage form of treating or improving the condition of benign prostatic hyperplasia, the field of preparing tamsulosin tablet
CN1652760AInactive Publication Date: 2005-08-10SYNTHON BV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SYNTHON BV
Publication Date
2005-08-10
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention relates to pharmaceutical tablets comprising low amounts of tamsulosim. The invention further relates to the manufacturing process and the therapeutic use of these compounds for the treatment of bening prostatic hyperplasia.
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Description

Background of the invention

[0001] The present invention relates to pharmaceutical tablets comprising tamsulosin, unit dosage forms prepared therefrom and methods of preparing the pharmaceutical tablets.

[0002] Tamsulosin is the common name for 5-[2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy-benzenesulfonamide of the following formula (1) .

[0003]

[0004] It is disclosed in EP 34432 and US 4731478 as a pharmaceutically active substance having alpha-adrenergic blocking activity for the treatment of cardiac insufficiency and benign prostatic hyperplasia.

[0005] The enantiomer (R)-Tamsulosin in hydrochloride form has been marketed in various countries, including the United States, for the treatment of symptoms of benign prostatic hyperplasia (also known as BPH), such as problems with urine output and frequency. The above-mentioned approved drug product is an oral capsule dosage form containing only 0.4 mg of tamsulosin hydrochloride. The capsules provide cont...

Claims

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