Double-layer press filter for metronidazole production

Abstract

The utility model discloses a double-layer press filter for metronidazole production, which comprises a press filter body, an upper cover is arranged above the press filter body, a feed port and an air inlet are sequentially arranged above the upper cover from left to right, and an upper flange and a lower flange are respectively arranged on the outer surface of the upper cover and the outer surface of the press filter body. The upper flange and the lower flange are connected through fixing bolts, a discharging opening is formed in the lower portion of the press filter body, a valve is installed at the end opening position of the discharging opening, a buffer plate is detachably connected to the left side of the inner wall of the press filter body, and a first filter screen and a second filter screen are detachably connected to the lower portion of the buffer plate in sequence from top to bottom; the first filter screen is designed to be of a wave-shaped structure; according to the device, the buffer plate is arranged, so that the loss of the filter screen is reduced, and a drainage effect is also achieved; due to the design of the double-layer filter screen, the purpose of double filtration is achieved, the filter area of the first filter screen is increased due to the design of the wave-shaped structure, and then the yield of solid products or the quality of liquid products is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of filter presses, in particular to a double-layer filter press for metronidazole production. Background Art

[0002] Metronidazole (2-methyl-5-nitro-1H-imidazole-1-ethanol) is an antibiotic and antiprotozoal agent. It is mainly used to treat or prevent systemic or local infections caused by anaerobic bacteria, such as anaerobic infections in the abdominal cavity, digestive tract, female reproductive system, lower respiratory tract, skin and soft tissue, bones and joints. It is also effective for sepsis, endocarditis, meningeal infection and colitis caused by antibiotic use. It is often used in combination with tetanus antitoxin (TAT) to treat tetanus. It can also be used for oral anaerobic infections.

[0003] Metronidazole API is currently produced by many domestic enterprises. Most of them adopt the traditional kettle reaction production process, which uses reactor intermittent production and has many operating procedures (weighing, feeding, reaction, material transfer, post-processing, solid-liquid separation). Many of these procedures, such as feeding and solid-liquid separation, require a lot of manual operation, which is labor-intensive and has low production efficiency. The continuous flow process of microchannel reactor solves this problem well. When using this continuous flow process to produce metronidazole, the product of each reaction step is solid and needs to be separated from the solid in the end. The filter press is the most commonly used solid-liquid separation equipment.

[0004] The filter press consists of a liquid cup and a filter funnel. It is characterized by an air-inflating cover on the top of the filter funnel to seal the funnel. The air-inflating cover is connected to the inner cavity of the filter funnel through a one-way valve. There is a gap at the bottom of the funnel, which is connected to the liquid cup. It is a small device for filter pressing. By adding an air-inflating cover on the top of the filter funnel, the inside of the filter funnel is inflated with air to increase its internal pressure, thereby achieving the purpose of filter pressing.

[0005] The filter press of the prior art uses a layer of filter medium. During use, it is inevitable that the filter cloth will be damaged, perforated, and cause material leakage accidents, affecting the yield of solid products or the quality of liquid products, and the filter screen will often be clogged. In addition, the filter screen plate used in the existing filter press has a small filtration area. When the existing filter press is used to filter fluids, especially high-viscosity fluids, there are problems of slow filtration speed and long filtration time, resulting in low filtration efficiency, which in turn affects the yield of solid products or the quality of liquid products. Utility Model Content

[0006] The utility model aims to provide a double-layer filter press for metronidazole production to solve the problems raised in the above-mentioned background technology.

[0007] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0008] A double-layer filter press for metronidazole production comprises a filter press body, an upper cover is installed above the filter press body, a feed port and an air inlet are installed above the upper cover in sequence from left to right, an upper flange and a lower flange are installed on the outer surface of the upper cover and the outer surface of the filter press body respectively, the upper flange and the lower flange are connected by fixing bolts, a feed port is installed below the filter press body, and a valve is installed at the port position of the feed port, a buffer plate is detachably connected to the left side of the inner wall of the filter press body, a first filter screen and a second filter screen are detachably connected below the buffer plate in sequence from top to bottom, and the first filter screen is designed in a wavy structure.

[0009] As a further solution of the utility model: a conical recess is formed downward at the bottom of the filter press body at a position corresponding to the filter holes of the second filter screen, and a discharge port is formed downward at the center of the conical recess. The valve is detachably connected to the discharge port. This structural design can reduce the residual discharge fluid and can also act as a guide plate to accelerate the discharge speed of the fluid and improve the fluid filtration efficiency.

[0010] As a further solution of the utility model: a rubber sealing ring is installed below the upper cover, and the structural design is adopted to improve the sealing between the upper cover and the filter press body, thereby improving the filtration efficiency of the solution in the filter press body.

[0011] As a further solution of the utility model: the opposite sides of the upper flange and the lower flange are respectively on the same horizontal line with the opposite sides of the upper cover and the filter press body. This structural design facilitates the installation and disassembly of the upper flange and the lower flange by fixing bolts, and has a simple structure and strong practicality.

[0012] As a further solution of the utility model: the buffer plate is designed with an inclined structure. With the structural design, when the solution to be filtered enters the interior of the filter press body from the feed inlet, the solution to be filtered is buffered by the buffer plate and then falls onto the first filter screen for filtration, thereby reducing the loss of the filter screen. At the same time, impurities in the solution to be filtered are not easy to break through the filter screen and fall into the bottom of the filter press body, thereby improving the filtration quality of the solution to be filtered.

[0013] As a further solution of the present invention: the first filter screen is made of a relatively hard material and is used for primary filtration, and the second filter screen is a precision filter screen.

[0014] As a further solution of the present invention: the first filter screen can also be designed in a folded line structure.

[0015] As a further solution of the utility model: three supporting legs are evenly installed at the lower part of the filter press body, so that the filter press body is suspended and supported on the ground.

[0016] Compared with the prior art, the beneficial effects of the utility model are: the utility model has a novel structure and adopts a buffer plate setting, which can reduce the loss of the filter screen on the one hand, and on the other hand, can also play a role in drainage, so that the fluid flowing in from the feed port is in a continuous flow state, so that the material can quickly pass through the first filter screen, greatly improving the efficiency and quality of the filter press.

[0017] By detachably installing the first filter screen and the second filter screen inside the filter press body, not only the purpose of double filtration is achieved and the filtration efficiency is improved, but also the problems of filter screen clogging and material leakage are solved, and the service life of the filter screen is increased; and the first filter screen is designed with a wavy structure, which is conducive to increasing the filtration area of ​​the first filter screen, thereby greatly improving the filtration speed and reducing the residual fluid to be filtered, shortening the filtration time, increasing the filtration efficiency, and thus improving the solid product yield or liquid product quality; and the detachable design allows users to choose different filter screens according to the filtering of different materials, ensuring that the filter screen can filter different materials and is more practical.

[0018] The bottom of the filter press body in the present application adopts a conical structure design, which is not only helpful in reducing the residual of the discharged fluid, especially the residual of high-viscosity fluid; it can also act as a guide plate, accelerate the discharge speed of the fluid, and improve the fluid filtration efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 This is a schematic diagram of the main cross-sectional structure of a double-layer filter press for metronidazole production according to an embodiment of the utility model;

[0020] Figure 2 This is a schematic diagram of the structure of the first filter screen described in an embodiment of the utility model;

[0021] In the figure: 1-filter body, 2-upper cover, 3-feed port, 4-air inlet, 5-upper flange, 6-lower flange, 7-fixing bolts, 8-buffer plate, 9-first filter screen, 10-second filter screen, 11-discharge port, 12-valve, 13-support foot. DETAILED DESCRIPTION

[0022] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0023] Example 1

[0024] See also Figure 1 In the embodiment of the utility model, a double-layer filter press for metronidazole production includes a filter press body 1, an upper cover 2, a feed port 3, an air inlet 4, an upper flange 5, a lower flange 6, a fixing bolt 7, a buffer plate 8, a first filter screen 9, a second filter screen 10, a feed port 11, a valve 12, and a support foot 13. The upper cover 2 is installed above the filter press body 1, and a conical recessed portion is formed downward at the bottom of the filter press body 1 corresponding to the filter hole of the second filter screen 10, and a feed port 11 is formed downward at the center of the conical recessed portion, and the valve 12 is detachably connected to the feed port 11. This structural design can not only help reduce the residual fluid in the process of discharging metronidazole, but also help reduce the residual high-viscosity fluid; on the other hand, the structural design of the conical recessed portion can also play the role of a guide plate, which can accelerate the discharge speed of the fluid and improve the fluid filtration efficiency. A rubber sealing ring is installed below the upper cover 2 to improve the sealing between the upper cover 2 and the filter press body 1, thereby improving the filtration efficiency of the solution in the metronidazole production in the filter press body 1.

[0025] The upper part of the upper cover 2 is provided with a feed port 3 and an air inlet 4 from left to right, and the outer surface of the upper cover 2 and the outer surface of the filter press body 1 are provided with an upper flange 5 and a lower flange 6, respectively. Furthermore, the opposite sides of the upper flange 5 and the lower flange 6 are respectively on the same horizontal line with the opposite sides of the upper cover 2 and the filter press body 1, so that the upper flange 5 and the lower flange 6 can be easily installed and removed by fixing bolts 7. The structure is simple and the practicability is strong. The upper flange 5 and the lower flange 6 are connected by fixing bolts 7. A feed port 11 is provided below the filter press body 1, and the end of the feed port 11 is provided with a feed port 12. A valve 12 is installed at the mouth position, and a buffer plate 8 is detachably connected to the left side of the inner wall of the filter press body 1. Further, the buffer plate 8 is designed in an inclined structure. When the solution in metronidazole production (i.e., the solution to be filtered) enters the inside of the filter press body 1 from the feed port 3, the solution in the metronidazole production is buffered by the buffer plate 8, and then falls on the first filter screen 9 for filter pressing, which reduces the loss of the first filter screen 9. At the same time, impurities in the solution in the metronidazole production are not easy to break through the first filter screen 9 and fall into the bottom of the filter press body 1, thereby improving the filter pressing quality of the solution in the metronidazole production. The present application adopts the buffer plate 8 setting, which can reduce the loss of the filter screen on the one hand, and on the other hand, it can also play a role in drainage, so that the fluid flowing in from the feed port 3 is in a continuous flow state, so that the material passes through the first filter screen 9 quickly, greatly improving the efficiency of filtration and the effect of filtration.

[0026] The first filter screen 9 and the second filter screen 10 are detachably connected to the bottom of the buffer plate 8 from top to bottom. The detachable design allows the user to choose different filter screens according to filtering different materials, ensuring that the filter screens can filter different materials, which is more practical. The first filter screen 9 is used for primary filtration, and its material is relatively hard. The first filter screen 9 is designed in a wavy structure. The use of this structural design is conducive to increasing the filtration area of ​​the first filter screen 9, thereby greatly improving the filtration speed and reducing the residual fluid to be filtered, shortening the filtration time, increasing the filtration efficiency, and thus improving the solid product yield or the liquid product quality. The second filter screen 10 is a precision filter screen; the present application adopts a double-layer filter screen design, which can achieve the purpose of double filtration compared with the existing one-layer filter medium. During use, the first filter screen 9 filters large solid particles and sharp objects in the material to prevent large particles and sharp objects from damaging the first filter screen 9. Then, the second filter screen 10 performs secondary filtration on the mixed liquid containing small particles, while preventing more particles from clogging the first filter screen 9, thereby increasing the use time of the filter screen and improving the filtration efficiency; further, during use, if the filter cloth of the first filter screen 9 is damaged and perforated, the second filter screen 10 can continue to filter the liquid to avoid material leakage accidents, so as not to affect the solid product yield or the liquid product quality.

[0027] Three legs 13 are evenly installed at the lower part of the filter press body 1, so that the filter press body 1 is suspended and supported on the ground, which is convenient for discharging operation.

[0028] Working principle: When using the double-layer filter press for metronidazole production, the solution in metronidazole production is introduced into the filter press body 1 from the feed port 3, and then the solution is buffered by the buffer plate 8, and the buffered solution falls into the first filter screen 9 and the second filter screen 10 inside the filter press body 1, and at the same time, the inside of the filter press body 1 is pressurized through the air inlet 4, so that the solution in metronidazole production is filtered, and the filtered solution falls into the bottom of the filter press body 1, and then the valve 12 of the feed port 11 is opened to collect the solution in metronidazole production, thereby completing a series of work. This device only highlights the innovative structure, and other structures not explained in detail in this specification are all prior art known to professional and technical personnel in this field, and will not be described in detail here.

[0029] Example 2

[0030] See also Figure 2 , which is different from Embodiment 1 in that the first filter screen 9 can also be designed in a folded line structure.

[0031] It is obvious to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above, and that the present invention can be implemented in other specific forms without departing from the spirit or essential features of the present invention. Therefore, the embodiments should be regarded as exemplary and non-restrictive from any point of view, and the scope of the present invention is defined by the appended claims rather than the above description, and it is intended that all changes falling within the meaning and scope of the equivalent elements of the claims be included in the present invention. Any reference numeral in a claim should not be regarded as limiting the claim to which it relates.

[0032] In addition, it should be understood that although the present specification is described according to implementation modes, not every implementation mode contains only one independent technical solution. This description of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment may also be appropriately combined to form other implementation modes that can be understood by those skilled in the art.

Claims

1. A double-layer filter press for metronidazole production, characterized in that: The invention comprises a filter press body (1), wherein an upper cover (2) is installed above the filter press body (1), and a feed port (3) and an air inlet (4) are installed above the upper cover (2) in sequence from left to right, an upper flange (5) and a lower flange (6) are installed on the outer surface of the upper cover (2) and the outer surface of the filter press body (1) respectively, and the upper flange (5) and the lower flange (6) are connected by fixing bolts (7), a feed port (11) is installed below the filter press body (1), and a valve (12) is installed at the port position of the feed port (11), a buffer plate (8) is detachably connected to the left side of the inner wall of the filter press body (1), and a first filter screen (9) and a second filter screen (10) are detachably connected below the buffer plate (8) in sequence from top to bottom, and the first filter screen (9) is designed in a wavy structure.

2. A double-layer filter press for metronidazole production according to claim 1, characterized in that: A conical recess is formed downward at a position on the bottom of the filter press body (1) corresponding to the filter holes of the second filter screen (10).

3. A double-layer filter press for metronidazole production according to claim 1, characterized in that: A rubber sealing ring is installed below the upper cover (2).

4. A double-layer filter press for metronidazole production according to claim 1, characterized in that: The opposite sides of the upper flange (5) and the lower flange (6) are respectively on the same horizontal line as the opposite sides of the upper cover (2) and the filter press body (1).

5. A double-layer filter press for metronidazole production according to claim 1, characterized in that: The buffer plate (8) is designed to be an inclined structure.

6. A double-layer filter press for metronidazole production according to claim 1, characterized in that: The first filter screen (9) is made of a relatively hard material, and the second filter screen (10) is a precision filter screen.

7. A double-layer filter press for metronidazole production according to claim 1 or 6, characterized in that: The first filter screen (9) may also be designed in a folded line structure.

8. A double-layer filter press for metronidazole production according to claim 1, characterized in that: Three supporting legs (13) are evenly installed at the lower part of the filter press body (1).

Images