Dissolving equipment for medicine test

Abstract

The utility model discloses dissolving equipment for a medicine test, and relates to the technical field related to the medicine test. The stirring device comprises a bottom plate, a middle ring plate, a cover plate, a top plate and stirring rods, two symmetrically distributed side arc plates are fixed to the peripheries of the bottom plate and the middle ring plate, the middle ring plate is located above the bottom plate, a hollow rotating shaft is rotationally connected into the top plate in a penetrating mode, and rubber blocks distributed in an annular array are fixed into an inner cavity of the rotating shaft; a stirring rod is clamped in the rubber block, and a stirring rod is fixed on the periphery of the lower part of the stirring rod; a guide rail is fixed to the top face of the top plate, and a rack is movably inserted into the guide rail. By arranging the guide rail, the rack, the rotating shaft, the gear, the stirring rod, the top plate, the rubber block and the cover plate, the problems that the stirring dissolution rate needs to be increased under the condition of no electric drive, a stirring part and a mechanical structure are not easy to detach and clean when being combined for use, and solution splashing is easily caused during high-speed stirring dissolution are solved.

Description

Technical Field

[0001] The utility model belongs to the technical field related to drug testing, and particularly relates to a dissolving device for drug testing. Background Art

[0002] Drug sensitivity test is an experiment to test the sensitivity of drugs to the body. The commonly used experimental method is skin sensitivity test. Most drugs need to undergo strict tests before leaving the factory to ensure that the efficacy is normal and qualified. Drugs are divided into solid and liquid forms. Most drugs need to be dissolved in relevant solvents during the test to facilitate subsequent tests. However, there are some disadvantages in the dissolution process:

[0003] 1. Conventional drug dissolution is mostly carried out in a beaker. The drug and solvent are put in, and then stirred with a glass rod to dissolve. However, this type of dissolution method is not very efficient. If an electric drive is added to stir and dissolve, it is not convenient and practical on the test bench. Therefore, how to increase the efficiency of stirring and dissolving without an electric drive is a problem that needs to be solved;

[0004] 2. Secondly, most glass rods need to be cleaned immediately after stirring and dissolving the drugs. If a mechanical structure or electric drive is added, it will be difficult to disassemble and clean, which will increase the working time;

[0005] 3. Finally, when dissolving by high-speed stirring, it is easy to cause the solution to splash out, which needs to be improved. Utility Model Content

[0006] The utility model aims to provide a dissolution device for drug testing. By arranging guide rails, racks, rotating shafts, gears, stirring rods, top plates, rubber blocks and cover plates, the utility model solves the problems of increasing the stirring and dissolving rate without electric drive, the difficulty in disassembling and cleaning the stirring part when used in combination with a mechanical structure, and the easy splashing of the solution during high-speed stirring and dissolving.

[0007] In order to solve the above technical problems, the utility model is realized by the following technical solutions:

[0008] The utility model is a dissolution device for drug testing, comprising a bottom plate, a middle ring plate, a cover plate, a top plate and a stirring rod, wherein two symmetrically distributed side arc plates are fixed to the outer peripheries of the bottom plate and the middle ring plate, the middle ring plate is located above the bottom plate, a screw rod is connected through a transverse thread in the side arc plate, and the ends of the two screw rods close to each other are both rotatably connected to a clamping plate, the top plate is located above the middle ring plate, a hollow rotating shaft is rotatably connected through the top plate, and rubber blocks distributed in an annular array are fixed in the inner cavity of the rotating shaft, a stirring rod is clamped in the rubber block, and a stirring rod is fixed to the outer periphery of the lower part of the stirring rod;

[0009] A gear is fixed on the outer periphery of the upper part of the rotating shaft, a guide rail is fixed on the top surface of the top plate, a rack is movably inserted in the guide rail, and the toothed part of the rack is meshed and connected with the gear.

[0010] Furthermore, a beaker is placed on the bottom plate between the two side arc plates, and the inner arc surfaces of the two clamping plates contact the outer wall of the beaker.

[0011] Furthermore, the lower part of the stirring rod passes through the middle ring plate and is located directly above the beaker, and two cover plates are arranged above the beaker, wherein slots are opened in the cover plates, and both cover plates are plugged into the outer periphery of the stirring rod through the slots, and the cover plates are located above the stirring rod.

[0012] Furthermore, a plug rod is symmetrically fixed to the upper end of the middle ring plate, and the top of the plug rod extends through the top plate and is fixed with a head, a spring is provided on the outer sleeve of the plug rod, and the upper and lower ends of the spring are fixedly connected to the top plate and the middle ring plate respectively.

[0013] Furthermore, a lateral convex groove is provided in the guide rail, and the toothed portion of the rack extends from the opening of the convex groove to engage with the gear, the top and bottom of the inner cavity of the guide rail are both rollingly connected with balls, and the upper and lower surfaces of the rack are in contact with the balls at corresponding positions.

[0014] Furthermore, a handle is fixed to one end of the rack.

[0015] Furthermore, the diameter of the middle ring plate is equal to the diameter of the bottom plate, and the diameter of the middle ring plate is greater than the maximum length of the top plate.

[0016] The utility model has the following beneficial effects:

[0017] 1. The utility model solves the problem of increasing the stirring and dissolving rate without electric drive by arranging guide rails, racks, rotating shafts, gears, stirring rods and top plates; medicines requiring solvents and solvents are put into a beaker, the top plate is pressed down, the lower part of the stirring rod is extended into the beaker, the rack is pulled to reciprocate in the guide rail, thereby meshing the transmission gear, the rotating shaft rotates back and forth, and then the stirring rod inside is rotated at a high speed, which is much faster than stirring with a handheld glass rod, thereby achieving efficient and rapid rotation and stirring, and quickly dissolving the medicine.

[0018] 2. The utility model solves the problem that the stirring part is not easy to disassemble and clean when used in combination with the mechanical structure by arranging a top plate, a rotating shaft and a rubber block; a rotating shaft connected in rotation is arranged inside the top plate, and a rubber block is used to clamp a stirring rod on the inner side of the rotating shaft. The stirring rod is a glass rod, and the static friction of the rubber block is fully utilized to clamp the stirring rod, so that it can rotate with the rotating shaft, and it can also be quickly disassembled for cleaning after work.

[0019] 3. The utility model solves the problem of solution splashing during high-speed stirring and dissolving by providing a cover plate. Before stirring, the lower part of the stirring rod is located in the beaker. At this time, two cover plates are staggered and inserted outside the stirring rod, and then covered on the upper end of the beaker to close the upper end of the beaker. Secondly, the staggered cover plates will block each other's slots without leaving any gaps. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] In order to more clearly illustrate the technical solutions of the embodiments of the present utility model, the drawings required for describing the embodiments are briefly introduced below.

[0021] Figure 1 A perspective view of a dissolution apparatus for testing a drug product;

[0022] Figure 2 A bottom view of a dissolution apparatus for testing a drug product;

[0023] Figure 3 This is the connection diagram of the top plate and the middle ring plate;

[0024] Figure 4 This is the connection diagram between the middle ring plate and the base plate;

[0025] Figure 5 This is the structural diagram of the cover;

[0026] Figure 6 is a top view of the top plate;

[0027] Figure 7 This is the structural diagram of the guide rail.

[0028] Reference numerals:

[0029] 1. Bottom plate; 101. Side arc plate; 102. Screw; 1021. Clamp; 2. Middle ring plate; 201. Insert rod; 2011. Head; 202. Spring; 3. Cover plate; 301. Slot; 4. Top plate; 401. Rotating shaft; 4011. Gear; 4012. Rubber block; 402. Guide rail; 4021. Ball; 403. Rack; 4031. Handle; 5. Stirring rod; 501. Stirring rod; 6. Beaker. DETAILED DESCRIPTION

[0030] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the accompanying drawings in the embodiments of the present invention.

[0031] See also Figure 1-7As shown, the utility model is a dissolution device for drug testing, comprising a bottom plate 1, a middle ring plate 2, a cover plate 3, a top plate 4 and a stirring rod 5. Two symmetrically distributed side arc plates 101 are fixed to the outer peripheries of the bottom plate 1 and the middle ring plate 2. The middle ring plate 2 is located above the bottom plate 1. A screw rod 102 is connected through a transverse thread in the side arc plate 101, and the ends of the two screw rods 102 that are close to each other are both rotatably connected to a clamping plate 1021. The top plate 4 is located above the middle ring plate 2. A hollow rotating shaft 401 is rotatably connected through the top plate 4. Rubber blocks 4012 distributed in a ring array are fixed in the inner cavity of the rotating shaft 401. The stirring rod 5 is clamped in the rubber block 4012, and a stirring rod 501 is fixed to the outer periphery of the lower part of the stirring rod 5.

[0032] The bottom plate 1 and the middle ring plate 2 are fixedly connected as one body through the side arc plate 101. The screw 102 in the side arc plate 101 rotates to make the clamping plate 1021 move linearly, which is used to clamp and fix the beaker 6 container used for dissolution to avoid deviation during the dissolution process. During dissolution, the rotating shaft 401 rotates, and the rubber block 4012 in the rotating shaft 401 clamps the stirring rod 5 by static friction, so that when the rotating shaft 401 rotates, the stirring rod 5 and the stirring rod 501 at its lower part are driven to rotate, so as to achieve stirring and dissolving.

[0033] A gear 4011 is fixed to the outer periphery of the upper part of the rotating shaft 401, a guide rail 402 is fixed to the top surface of the top plate 4, and a rack 403 is movably inserted in the guide rail 402, and the toothed portion of the rack 403 is meshed with the gear 4011;

[0034] The rack 403 is pulled to move back and forth in the guide rail 402, thereby rotating the meshing gear 4011, and further rotating the shaft 401 to perform reciprocating rotation.

[0035] A beaker 6 is placed on the bottom plate 1 between the two side arc plates 101, and the inner arc surfaces of the two clamping plates 1021 contact the outer wall of the beaker 6;

[0036] The beaker 6 is used as a dissolving container for the dissolved medicine, and the two clamps 1021 are close to each other to clamp the beaker 6 to prevent it from deviating and shaking.

[0037] The lower part of the stirring rod 5 passes through the middle ring plate 2 and is located directly above the beaker 6, and two cover plates 3 are arranged above the beaker 6, and slots 301 are opened in the cover plates 3. Both cover plates 3 are inserted into the outer periphery of the stirring rod 5 through the slots 301, and the cover plates 3 are located above the stirring rod 501;

[0038] The lower part of the stirring rod 5 is used for stirring and dissolving the main stirring part. The stirring rod 5 is normally located above the beaker 6 and extends into the beaker 6 when in use. At this time, the two cover plates 3 are staggered and inserted outside the stirring rod 5, and then covered on the upper end of the beaker 6 to close the upper end of the beaker 6. The staggered cover plates 3 will block each other's slots 301.

[0039] The upper end of the middle ring plate 2 is symmetrically fixed with a plug rod 201, and the top of the plug rod 201 passes through the top plate 4 and is fixed with a head 2011. The plug rod 201 is provided with a spring 202, and the upper and lower ends of the spring 202 are respectively fixedly connected to the top plate 4 and the middle ring plate 2;

[0040] The insertion rod 201 is used to flexibly connect the top plate 4. Under normal conditions, the top plate 4 is supported by the spring 202 and limited by the head 2011. In this state, the stirring rod 5 is located above the beaker 6. By pressing down the top plate 4, the lower part of the stirring rod 5 can be extended into the beaker 6 for stirring and dissolving.

[0041] A lateral convex groove is provided in the guide rail 402, and the toothed portion of the rack 403 extends from the opening of the convex groove and meshes with the gear 4011. The top and bottom of the inner cavity of the guide rail 402 are both rollingly connected with ball bearings 4021, and the upper and lower surfaces of the rack 403 are in contact with the ball bearings 4021 at corresponding positions; a handle 4031 is fixed at one end of the rack 403; the arrangement and distribution of the ball bearings 4021 help the rack 403 to be pulled more smoothly in the guide rail 402, and the handle 4031 is held to pull the rack 403 to reciprocate, thereby meshing with the transmission gear 4011 to rotate.

[0042] The diameter of the middle ring plate 2 is equal to that of the bottom plate 1 , and the diameter of the middle ring plate 2 is greater than the maximum length of the top plate 4 .

[0043] The specific working principle of the utility model is as follows: first, the medicine and solvent requiring a solvent are put into the beaker 6, and the beaker 6 is placed above the bottom plate 1. The screw 102 in the side arc plate 101 is rotated to make the clamping plate 1021 move linearly to clamp and fix the beaker 6 container for dissolution. Subsequently, the top plate 4 is pressed down, and the spring 202 is compressed, so that the lower part of the stirring rod 5 can be extended into the beaker 6. Subsequently, the two cover plates 3 are interlaced and inserted on the outside of the stirring rod 5, and then covered on the upper end of the beaker 6 to close the upper end of the beaker 6. Finally, the handle 4031 is held to pull the rack 403 to move back and forth in the guide rail 402, so that the meshing gear 4011 rotates, and then the rotating shaft 401 is used for reciprocating rotation. The stirring rod 5 is clamped by the rubber block 4012 in the rotating shaft 401 by static friction, so that when the rotating shaft 401 rotates, the stirring rod 5 and the stirring rod 501 at its lower part are driven to rotate, so as to achieve stirring and dissolving.

[0044] The above are only preferred embodiments of the present invention and do not limit the present invention. Any modification to the technical solutions recorded in the aforementioned embodiments and any equivalent replacement of some of the technical features therein, any modification, equivalent replacement, and improvement made are all within the protection scope of the present invention.

Claims

1. A dissolution device for drug testing, comprising a bottom plate (1), a middle ring plate (2), a cover plate (3), a top plate (4) and a stirring rod (5), characterized in that: Two symmetrically distributed side arc plates (101) are fixed to the outer peripheries of the bottom plate (1) and the middle ring plate (2); the middle ring plate (2) is located above the bottom plate (1); a screw rod (102) is connected to the side arc plate (101) through a transverse thread, and the ends of the two screw rods (102) that are close to each other are both rotatably connected to a clamping plate (1021); the top plate (4) is located above the middle ring plate (2); a hollow rotating shaft (401) is rotatably connected to the top plate (4); rubber blocks (4012) distributed in a ring array are fixed in the inner cavity of the rotating shaft (401); a stirring rod (5) is clamped in the rubber block (4012); and a stirring rod (501) is fixed to the outer periphery of the lower part of the stirring rod (5); A gear (4011) is fixed to the outer periphery of the upper part of the rotating shaft (401), a guide rail (402) is fixed to the top surface of the top plate (4), a rack (403) is movably inserted into the guide rail (402), and the toothed portion of the rack (403) is meshingly connected to the gear (4011).

2. A dissolution device for drug testing according to claim 1, characterized in that: A beaker (6) is placed on the bottom plate (1) between the two side arc plates (101), and the inner arc surfaces of the two clamping plates (1021) contact the outer wall of the beaker (6).

3. A dissolution device for drug testing according to claim 2, characterized in that: The lower part of the stirring rod (5) passes through the middle ring plate (2) and is located directly above the beaker (6), and two cover plates (3) are arranged above the beaker (6), wherein a slot (301) is provided in the cover plate (3), and the two cover plates (3) are both inserted into the outer periphery of the stirring rod (5) through the slot (301), and the cover plates (3) are located above the stirring rod (501).

4. A dissolution device for drug testing according to claim 1, characterized in that: The upper end of the middle ring plate (2) is symmetrically fixed with an insertion rod (201), and the top of the insertion rod (201) passes through the top plate (4) and extends out and is fixed with a head (2011). The outer sleeve of the insertion rod (201) is provided with a spring (202), and the upper and lower ends of the spring (202) are respectively fixedly connected to the top plate (4) and the middle ring plate (2).

5. A dissolution device for drug testing according to claim 1, characterized in that: A lateral convex groove is provided in the guide rail (402), and a toothed portion of the rack (403) extends from the opening of the convex groove to mesh with the gear (4011), and balls (4021) are rollingly connected to the top and bottom of the inner cavity of the guide rail (402), and the upper and lower surfaces of the rack (403) are in contact with the balls (4021) at corresponding positions.

6. A dissolution device for drug testing according to claim 1, characterized in that: A handle (4031) is fixed to one end of the rack (403).

7. A dissolution device for drug testing according to claim 1, characterized in that: The diameter of the middle ring plate (2) is equal to the diameter of the bottom plate (1), and the diameter of the middle ring plate (2) is greater than the maximum length of the top plate (4).

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