Lowering blood and blood pressure plants extract, preparation and applications thereof

Abstract

The invention provides plant extract with blood lipid reducing and blood pressure lowering effects, and a preparation method and an application thereof. The preparation method comprises the steps of mixing the flower and / or the flower bud of Chrysanthemum morifolium, extracting with 50-80% (v / v) aqueous ethanol at 60-100 DEG C for 1-3 hours to obtain extractive solution, adsorbing with macroporous adsorption resin, eluting with 60-90% (v / v) aqueous ethanol, collecting eluate, and drying until water content is lower than 12% to obtain the plant extract. The inventive extract contains more than 50% of effective ingredients such as galuteolin, celereoside, luteolin, apigenin, acacetin-7-rhamnosidgluoside, acacipetalin, flavonoid glycoside, and chlorogenic acid; and has blood lipid reducing and blood pressure lowering effects. Compared with the existing domestic and overseas products, the inventive extract has more complete efficacy, and more ideal effects in restoring normal blood lipid level and blood pressure level for demanded people.

Description

(1) Technical field

[0001] The invention relates to a plant extract for lowering blood fat and blood pressure, a preparation method thereof, and an application thereof in preparing a functional food with double effects of lowering blood fat and blood pressure. (2) Background technology

[0002] A large number of people at home and abroad have physiological phenomena of high blood lipids, blood sugar, and blood pressure. They are in great need of functional food conditioning with natural plants as raw materials, especially functional foods developed from food resources. The market demand is high. At present, people with high blood lipids are often accompanied by high blood sugar or high blood pressure, and there are many people with high blood lipids, blood sugar and blood pressure. However, the existing products are all single-function products, so it is very necessary to develop a product with multiple functions. Functional foods that assist in reducing blood fat, blood su...

Examples

Embodiment 1

[0023] Take 8000 grams of chrysanthemum (produced in Suichang County, Zhejiang Province) and grind it, add 32 kilograms of ethanol aqueous solution with a volume concentration of 80% volume concentration, heat and extract at 80 ° C for 2 hours, filter to obtain the extract, recover the ethanol in a vacuum from the extract, and concentrate Be about 1.15 to relative density, get paste 1856 grams. Take macroporous adsorption resin (model is AB-8, produced by Tianjin Nankai Hecheng Technology Co., Ltd.), soak in absolute ethanol for 24 hours, soak in distilled water for 24 hours, and wash three times, drain the water, take 320 liters of wet resin and pack it into a column . Immerse the resin with distilled water, add the paste, rinse with 640 liters of distilled water, discard the eluate, rinse with 320 liters of 20% volume concentration ethanol aqueous solution, and discard the ethanol after the ethanol is recovered by vacuum distillation. Then elute with 1280 liters of ethanol ...

Embodiment 2

[0025]Take 3000 grams of chrysanthemum (produced in Suichang County, Zhejiang Province), grind and pulverize, add 6021 kilograms of ethanol aqueous solution with a volume concentration of 50% volume concentration, extract at 60 ° C for 3 hours, filter to obtain the extract, and add 95% of the extract 6.7 liters of ethanol, stirred evenly, stood still for 2 hours, filtered again, the filtrate was vacuum recovered ethanol, concentrated to a relative density of about 1.10 to obtain 583 grams of paste. Take macroporous adsorption resin (model is AB-8, produced by Tianjin Nankai Hecheng Technology Co., Ltd.), soak in absolute ethanol for 24 hours, soak in distilled water for 24 hours, and wash three times, drain the water, take 420 liters of wet resin and pack it into a column . Immerse the resin with distilled water, add the paste, rinse with 840 liters of distilled water, discard the eluate, rinse with 420 liters of 10% ethanol aqueous solution, and discard the ethanol after the ...

Embodiment 3

[0027] Take 6000 grams of chrysanthemum (produced in Suichang County, Zhejiang Province), grind and pulverize, add 33 kilograms of ethanol aqueous solution with a volume concentration of 70% volume concentration, heat and extract at 100 ° C for 1 hour, filter to obtain the extract, and add 95% of the extract 3.5 liters of ethanol, stirred evenly, stood still for 0.5 hour, filtered again, the filtrate was vacuum recovered ethanol, concentrated to a relative density of about 1.15 to obtain 1183 grams of paste. Take macroporous adsorption resin (model is AB-8, produced by Tianjin Nankai Hecheng Technology Co., Ltd.), soak in absolute ethanol for 24 hours, soak in distilled water for 24 hours, and wash three times, drain the water, take 600 liters of wet resin and pack it into a column . Immerse the resin with distilled water, add the paste, rinse with 1200 liters of distilled water, discard the eluate, rinse with 600 liters of 15% ethanol aqueous solution, and discard the ethanol...

(1) Technical field

[0001] The invention relates to a plant extract for lowering blood fat and blood pressure, a preparation method thereof, and an application thereof in preparing a functional food with double effects of lowering blood fat and blood pressure. (2) Background technology

[0002] A large number of people at home and abroad have physiological phenomena of high blood lipids, blood sugar, and blood pressure. They are in great need of functional food conditioning with natural plants as raw materials, especially functional foods developed from food resources. The market demand is high. At present, people with high blood lipids are often accompanied by high blood sugar or high blood pressure, and there are many people with high blood lipids, blood sugar and blood pressure. However, the existing products are all single-function products, so it is very necessary to develop a product with multiple functions. Functional foods that assist in reducing blood fat, blood su...

Examples

Embodiment 1

[0023] Take 8000 grams of chrysanthemum (produced in Suichang County, Zhejiang Province) and grind it, add 32 kilograms of ethanol aqueous solution with a volume concentration of 80% volume concentration, heat and extract at 80 ° C for 2 hours, filter to obtain the extract, recover the ethanol in a vacuum from the extract, and concentrate Be about 1.15 to relative density, get paste 1856 grams. Take macroporous adsorption resin (model is AB-8, produced by Tianjin Nankai Hecheng Technology Co., Ltd.), soak in absolute ethanol for 24 hours, soak in distilled water for 24 hours, and wash three times, drain the water, take 320 liters of wet resin and pack it into a column . Immerse the resin with distilled water, add the paste, rinse with 640 liters of distilled water, discard the eluate, rinse with 320 liters of 20% volume concentration ethanol aqueous solution, and discard the ethanol after the ethanol is recovered by vacuum distillation. Then elute with 1280 liters of ethanol ...

Embodiment 2

[0025]Take 3000 grams of chrysanthemum (produced in Suichang County, Zhejiang Province), grind and pulverize, add 6021 kilograms of ethanol aqueous solution with a volume concentration of 50% volume concentration, extract at 60 ° C for 3 hours, filter to obtain the extract, and add 95% of the extract 6.7 liters of ethanol, stirred evenly, stood still for 2 hours, filtered again, the filtrate was vacuum recovered ethanol, concentrated to a relative density of about 1.10 to obtain 583 grams of paste. Take macroporous adsorption resin (model is AB-8, produced by Tianjin Nankai Hecheng Technology Co., Ltd.), soak in absolute ethanol for 24 hours, soak in distilled water for 24 hours, and wash three times, drain the water, take 420 liters of wet resin and pack it into a column . Immerse the resin with distilled water, add the paste, rinse with 840 liters of distilled water, discard the eluate, rinse with 420 liters of 10% ethanol aqueous solution, and discard the ethanol after the ...

Embodiment 3

[0027] Take 6000 grams of chrysanthemum (produced in Suichang County, Zhejiang Province), grind and pulverize, add 33 kilograms of ethanol aqueous solution with a volume concentration of 70% volume concentration, heat and extract at 100 ° C for 1 hour, filter to obtain the extract, and add 95% of the extract 3.5 liters of ethanol, stirred evenly, stood still for 0.5 hour, filtered again, the filtrate was vacuum recovered ethanol, concentrated to a relative density of about 1.15 to obtain 1183 grams of paste. Take macroporous adsorption resin (model is AB-8, produced by Tianjin Nankai Hecheng Technology Co., Ltd.), soak in absolute ethanol for 24 hours, soak in distilled water for 24 hours, and wash three times, drain the water, take 600 liters of wet resin and pack it into a column . Immerse the resin with distilled water, add the paste, rinse with 1200 liters of distilled water, discard the eluate, rinse with 600 liters of 15% ethanol aqueous solution, and discard the ethanol...