Filling method and filling system
Through the two-stage filling method, the combination of large flow coarse filling and small flow precision filling is solved, and the problems of low filling efficiency and easy equipment damage in the existing technology are achieved, and the efficient and precise filling process is achieved. It is suitable for Production demand for large-volume flasks.
Patent Information
- Application Number
- CN201910852934.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2019-09-10
- Publication Date
- 2024-12-31
- Estimated Expiration
- 2039-09-10
AI Technical Summary
The existing filling system is difficult to ensure high efficiency while ensuring filling accuracy, especially for large-volume bottles, and it is easy to damage the equipment during filling.
Using the two-stage filling method, first using a high flow first filling device for coarse filling, then using a small flow second filling device for fine filling, and multiple weighing tests ensure the accuracy of the filling amount. to avoid damage to the equipment.
It improves filling efficiency, is suitable for filling large-volume bottles, and ensures filling accuracy through multiple weighing inspections, avoids equipment damage, and meets the pharmaceutical factory's large-scale high-speed production needs.
Smart Images
Figure CN110467142B_ABST
Abstract
Description
Technical Field
[0001] The invention relates to a food and medicine packaging method and equipment, and in particular to a filling method and a filling system. Background Art
[0002] The filling system is the core part of the whole set of filling equipment, and the filling accuracy is the most important performance indicator to measure the filling system. At present, two sets of weighing sensors are generally used to weigh the medicine bottles before filling (i.e. tare weight) and the medicine bottles after filling (i.e. gross weight) to obtain the filling weight. However, this method cannot guarantee that each bottle can meet the target filling weight, but can only select the bottles with qualified filling. Its filling accuracy still depends almost on the accuracy of the filling system itself, that is, a fixed filling volume is given by conversion to obtain the pump stroke, and the final filling volume is completely determined by the filling pump and the supporting piping system. Even a filling system with online weighing can only determine the deviation of the current filling volume. The response after automatic calibration needs to take effect at least in the next cycle, and the accuracy control of the current filling cycle cannot be achieved.
[0003] Chinese patent CN 109592095 A discloses a filling precision control method and equipment, which separates rough filling and fine filling and controls them in sections. First, the bottle is placed on a weighing sensor for rapid filling (i.e., rough filling). After the weighing sensor detects that the weight reaches the set value, it is filled at a low speed (i.e., fine filling) until the target filling volume is reached. However, the above method uses the same set of equipment for both fillings (i.e., the rough filling and fine filling share the same pump, filling needle, and weighing sensor), resulting in a long filling cycle, greatly reducing the filling efficiency, and failing to meet the high-speed production requirements of pharmaceutical factories in large quantities. This filling method is not advisable, especially for large-capacity bottles such as large infusion bottles. In addition, during the filling process, especially during rough filling, the filling speed is fast, so the impact force on the bottle is very large. At this time, if there is a weighing sensor under the bottle, it is very easy to cause damage to the weighing sensor.
[0004] Existing technical solutions cannot ensure filling efficiency while ensuring filling accuracy. In order to ensure filling efficiency, larger filling needles are usually used, which makes it impossible to achieve fluid replenishment of several milligrams or more than ten milligrams, that is, it is difficult to achieve a high filling accuracy. Summary of the invention
[0005] The technical problem to be solved by the present invention is to overcome the deficiencies of the prior art and provide a filling method which is conducive to taking into account both production efficiency and filling accuracy and avoids damage to equipment.
[0006] The present invention further provides a filling system suitable for the above filling method.
[0007] In order to solve the above technical problems, the present invention adopts the following technical solutions:
[0008] A filling method comprises the following steps:
[0009] S1, the first weighing station weighs the empty bottle;
[0010] S2, the first filling device fills the empty bottle for the first time according to the set filling volume;
[0011] S3, the second weighing station weighs the bottle after the first filling;
[0012] S4, the second filling device performs a second filling on the bottle after the first filling, and the flow rate of the second filling device is less than the flow rate of the first filling device. If the target filling volume is K, the actual filling volume of the bottle measured in S3 for the first filling is K1, and the set filling volume for the second filling is K2, then K2 = K-K1;
[0013] S5. The third weighing station weighs the bottle after the second filling.
[0014] As a further improvement of the above technical solution: in step S5, if the weighing result is within the qualified range, the bottle filling is completed; if the weighing result is low, the second filling device refills the bottle until the weighing result is within the qualified range.
[0015] As a further improvement of the above technical solution: when the liquid level in the liquid buffer tank is low, the tail liquid is filled, including the steps of:
[0016] S6, the first weighing station weighs the empty bottle;
[0017] S7, the second filling device fills the weighed bottle and sets the filling volume as the target filling volume K;
[0018] S8. The third weighing station weighs the filled bottles.
[0019] As a further improvement of the above technical solution: in step S8, if the weighing result is within the qualified range, the filling of the bottle is completed; if the weighing result is low, the second filling device refills the bottle until the weighing result is within the qualified range.
[0020] As a further improvement of the above technical solution: in step S7, the second filling device uses multiple filling pumps to perform fine filling on multiple bottles in the same batch one by one until the tail liquid in the medicine liquid buffer tank is less than the sum of the target filling volumes of the next batch of bottles; when the tail liquid in the medicine liquid buffer tank is less than the sum of the target filling volumes of the next batch of bottles, the second filling device in step S7 gradually reduces the filling pumps involved in the filling.
[0021] As a further improvement of the above technical solution: the set filling volume for the first filling in step S2 is 0.8K-0.95K.
[0022] A filling system comprises a first weighing station, a first filling station, a second filling station and a conveying device for conveying bottles, wherein the first filling station is provided with a first filling device, a second weighing station is provided between the first filling station and the second filling station, the second filling station is provided with a second filling device and a third weighing station, and the diameter of the filling pipeline of the first filling device is greater than the diameter of the filling pipeline of the second filling device.
[0023] As a further improvement of the above technical solution: the first weighing station, the first filling device, the second weighing station and the second filling device are arranged in sequence along the conveying direction of the conveying device.
[0024] As a further improvement of the above technical solution: the third weighing station is located below the second filling device.
[0025] Compared with the prior art, the advantages of the present invention are as follows: the filling method disclosed in the present invention firstly weighs the empty bottles by using the first weighing station, the filling of the empty bottles is carried out in two stages, and the rough filling is completed by using the first filling device with a larger flow rate, and the fine filling is carried out by using the second filling device with a smaller flow rate, thereby shortening the production cycle, and the first filling adopts large flow filling, which greatly improves the production efficiency and is more suitable for the filling of large-capacity bottles, and at the same time, the second weighing station can be arranged downstream of the first filling device to avoid the impact of the first filling device during large-flow filling causing equipment damage, and after the first filling, the second weighing station is used to weigh to measure the actual filling volume of the first filling and calculate the filling volume required for the second filling, and combined with the second filling with a small flow rate, it is conducive to ensuring the filling accuracy (for example, when there are bubbles in the filling pipeline of the first filling device, resulting in inaccurate filling volume, the second filling device can be used to supplement), and the third weighing station is used to weigh the second time after the second filling, which is conducive to detecting whether the total filling volume of the bottle is qualified.
[0026] The filling system disclosed in the present invention comprises a first weighing station, a first filling station and a second filling station, wherein the first filling station is provided with a first filling device, a second weighing station is provided between the first filling station and the second filling station, and the second filling station is provided with a second filling device and a third weighing station, wherein the diameter of the filling pipeline of the first filling device is larger than the diameter of the filling pipeline of the second filling device, so that the filling of empty bottles is carried out in two stages, and the first filling device with a larger flow rate is used to complete the rough filling, and the second filling device with a smaller flow rate is used to perform the fine filling, thereby shortening the production cycle, and the first filling adopts the large flow filling, thus greatly improving the production efficiency, and being more suitable for the filling of large-capacity bottles, and the second weighing station is arranged at the downstream of the first filling device, so as to avoid the impact of the first filling device during the large flow filling to cause equipment damage, and whether the final filling amount of the bottle body is qualified can be detected by weighing for many times. BRIEF DESCRIPTION OF THE DRAWINGS
[0027] Figure 1 It is a schematic flow diagram of the filling method of the present invention.
[0028] Figure 2 It is a structural schematic diagram of the filling system of the present invention.
[0029] The numbers in the figure indicate: 1. first weighing station; 2. first filling device; 3. second weighing station; 4. second filling device; 5. third weighing station; 6. conveying device. DETAILED DESCRIPTION
[0030] The present invention is further described in detail below with reference to the accompanying drawings and specific embodiments.
[0031] Figure 1 An embodiment of the filling method of the present invention is shown. The filling method of this embodiment includes the following steps:
[0032] S1, the first weighing station 1 weighs the empty bottle;
[0033] S2, the first filling device 2 fills the empty bottle for the first time according to the set filling volume;
[0034] S3, the second weighing station 3 weighs the bottle after the first filling;
[0035] S4, the second filling device 4 performs a second filling on the bottle after the first filling, and the flow rate of the second filling device 4 is less than the flow rate of the first filling device 2. If the target filling volume is K, the actual filling volume of the bottle measured in S3 for the first filling is K1, and the set filling volume for the second filling is K2, then K2 = K-K1;
[0036] S5, the third weighing station 5 weighs the bottle after the second filling. The first weighing station 1, the second weighing station 3, and the third weighing station 5 can use existing weighing sensors to complete the weighing; the difference in flow rate between the first filling device 2 and the second filling device 4 can be achieved by changing the diameter of the silicone pipe and the filling needle.
[0037] In the filling method, the first weighing station 1 is used to weigh the empty bottles, and the filling of the empty bottles is carried out in two stages, and the first filling device 2 with a larger flow rate is used to complete the rough filling, and the second filling device 4 with a smaller flow rate is used to perform the fine filling. The first filling device 2 and the second filling device 4 can work at the same time, which shortens the production cycle, and the first filling adopts a large flow filling, which greatly improves the production efficiency and is more suitable for the filling of large-capacity bottles. At the same time, the second weighing station 3 can be set downstream of the first filling device 2 to avoid the impact of the first filling device 2 during large-flow filling causing damage to the second weighing station 3, and more weighing time can be provided, because in the production process, the time the bottle stays at each station is basically the same, if the first weighing station 3 is set downstream of the first filling device 2, the second weighing station 3 can be set downstream of the first filling device 2, so as ... The station 3 is merged under the first filling device 2 or the second filling device 4, which will shorten the weighing time. However, the existing weighing sensor response speed is difficult to meet the requirements, which may easily lead to inaccurate weighing. After the first filling, the second weighing station 3 is used to weigh to measure the actual filling volume of the first filling and calculate the filling volume required for the second filling, which is conducive to eliminating the deviation between the actual filling volume of the first filling and the set value. Combined with the second filling with a small flow rate, it is conducive to ensuring the filling accuracy (for example, when there are bubbles in the filling pipeline of the first filling device 2, resulting in inaccurate filling volume, the second filling device 4 can be used to supplement it). After the second filling, the third weighing station 5 is used for the second weighing, which is conducive to detecting whether the final filling volume of the bottle is qualified.
[0038] Furthermore, in this embodiment, if the weighing result in step S5 is within the qualified range, the bottle filling is completed; if the weighing result is low, the second filling device 4 refills the bottle until the weighing result reaches the qualified range. After the second weighing, the bottle is refilled again to make the final filling volume of the bottle close to the set value, which is conducive to further improving the filling accuracy (for example, when there are bubbles in the filling pipeline of the first filling device 2, resulting in inaccurate filling volume, the second filling device 4 can be used to supplement, and if the second filling device 4 is still inaccurate after replenishment, it can be supplemented again through refilling).
[0039] Furthermore, in this embodiment, when the liquid medicine level in the liquid medicine buffer tank is low, tail liquid filling is performed, including the steps of:
[0040] S6, the first weighing station 1 weighs the empty bottle;
[0041] S7, the second filling device 4 fills the weighed bottle and sets the filling volume to the target filling volume K;
[0042] S8, the third weighing station 5 weighs the filled bottle. Since the liquid in the liquid buffer tank is at a low level, the first filling device 2 with a large flow rate is skipped at this time, and the second filling device 4 with a small flow rate is directly used for filling, which is conducive to the reliable and stable operation of the filling system and ensures the filling accuracy.
[0043] Furthermore, in this embodiment, if the weighing result in step S8 is within the qualified range, the bottle filling is completed; if the weighing result is too low, the second filling device 4 refills the bottle until the weighing result reaches the qualified range. After the second weighing, the liquid is replenished again, so that the final filling volume of the bottle is close to the set value, which is conducive to further improving the filling accuracy.
[0044] Furthermore, in this embodiment, the second filling device 4 in step S7 uses multiple filling pumps to perform fine filling on multiple bottles in the same batch one by one, which is conducive to ensuring the production efficiency of the second filling, until the tail liquid in the medicine liquid buffer tank is less than the sum of the target filling volumes of the next batch of bottles; when the tail liquid in the medicine liquid buffer tank is less than the sum of the target filling volumes of the next batch of bottles, the second filling device 4 in step S7 gradually reduces the filling pumps involved in the filling, for example, using a 6-4-2-1 method to gradually reduce it to one, so that the remaining tail liquid in the medicine liquid buffer tank can be reduced as much as possible.
[0045] As a preferred technical solution, the set filling volume of the first filling in step S2 is 0.8K-0.95K. The set filling volume of the first filling is set to 80%-95%, which can maximize the filling efficiency and leave room for the second filling and subsequent refilling, thereby ensuring the final filling accuracy.
[0046] Taking the filling of a certain product of 5.3 ml as an example, the principle of the filling method of the present invention is explained:
[0047] 1) Assume that the volume weighed after rough filling is 5 ml;
[0048] 2) The target filling volume during precision filling is 0.3 ml. Assuming that the filling accuracy error during precision filling is ±2%, the actual overall accuracy is 0.3*(±2%) / 5.3*100%=±0.113%;
[0049] 3) The target filling volume during precision filling is 0.3 ml. Assuming that the filling accuracy error during precision filling is ±5%, the actual overall accuracy is 0.3*(±5%) / 5.3*100%=±0.283%.
[0050] Through many tests, it is concluded that the accuracy error of fine filling with small diameter silicone tubes will not exceed ±2%, so the overall filling accuracy can meet the requirement of ±0.5%.
[0051] Figure 2 An embodiment of the filling system of the present invention is shown. The filling system of this embodiment comprises a first weighing station 1, a first filling station, a second filling station and a conveying device 6 for conveying bottles. The first filling station is provided with a first filling device 2, a second weighing station 3 is provided between the first filling station and the second filling station, and the second filling station is provided with a second filling device 4 and a third weighing station 5. The diameter of the filling pipeline of the first filling device 2 is larger than the diameter of the filling pipeline of the second filling device 4. In this filling system, the filling of empty bottles is carried out in two stages, and the first filling device 2 with a larger flow rate is used to complete the rough filling, and the second filling device 4 with a smaller flow rate is used to perform the fine filling, which shortens the production cycle, and the first filling adopts a large flow filling, which greatly improves the production efficiency and is more suitable for the filling of large-capacity bottles. At the same time, the second weighing station 3 is arranged downstream of the first filling device 2 to avoid the impact of the first filling device 2 during the large flow filling to cause damage to the equipment. Through multiple weighing, it can be detected whether the final filling amount of the bottle is qualified.
[0052] Further, in this embodiment, the first weighing station 1, the first filling device 2, the second weighing station 3 and the second filling device 4 are arranged in sequence along the conveying direction of the conveying device 6. The first weighing station 1, the first filling device 2, the second weighing station 3 and the second filling device 4 are arranged in sequence along the conveying direction of the conveying device 6, so that the overall structure of the filling system is compact, the operation efficiency is high, and the footprint is small.
[0053] Furthermore, in this embodiment, the third weighing station 5 is located below the second filling device 4. Since the second filling device 4 adopts a small flow filling, even if the third weighing station 5 is arranged below the second filling device 4, it is not easy to cause the third weighing station 5 to be damaged. On the other hand, it can also realize weighing and filling at the same time, that is, online weighing.
[0054] Although the present invention has been disclosed as above with preferred embodiments, it is not intended to limit the present invention. Any technician familiar with the art can make many possible changes and modifications to the technical solution of the present invention by using the technical content disclosed above without departing from the scope of the technical solution of the present invention, or modify it into an equivalent embodiment of equivalent changes. Therefore, any simple modification, equivalent change and modification made to the above embodiments according to the technical essence of the present invention without departing from the content of the technical solution of the present invention should fall within the scope of protection of the technical solution of the present invention.
Claims
1. A filling method, characterized in that: The following steps are involved: S1, the first weighing station (1) weighs the empty bottle; S2, the first filling device (2) performs a first filling of the empty bottle according to a set filling volume, and the first filling device (2) is located downstream of the first weighing station (1); S3, a second weighing station (3) weighs the bottle after the first filling, and the second weighing station (3) is located downstream of the first filling device (2); S4, the second filling device (4) performs a second filling on the bottle body after the first filling, the flow rate of the second filling device (4) is less than the flow rate of the first filling device (2), if the target filling volume is K, the actual filling volume of the bottle body measured in S3 for the first filling is K1, and the set filling volume for the second filling is K2, then K2=K-K1; S5, the third weighing station (5) weighs the bottle after the second filling; When the liquid level in the liquid buffer tank is low, the tail liquid filling is carried out, including the following steps: S6, the first weighing station (1) weighs the empty bottle; S7, the second filling device (4) fills the weighed bottle and sets the filling volume to the target filling volume K; S8. The third weighing station (5) weighs the filled bottle.
2. The filling method according to claim 1, characterized in that: In step S5, if the weighing result is within the qualified range, the bottle filling is completed; if the weighing result is too low, the second filling device (4) refills the bottle until the weighing result is within the qualified range.
3. The filling method according to claim 1, characterized in that: In step S8, if the weighing result is within the qualified range, the filling of the bottle is completed; if the weighing result is too low, the second filling device (4) refills the bottle until the weighing result is within the qualified range.
4. The filling method according to claim 1, characterized in that: In step S7, the second filling device (4) uses a plurality of filling pumps to perform precision filling on a plurality of bottles in the same batch one by one until the tail liquid in the liquid medicine buffer tank is less than the sum of the target filling volumes of the next batch of bottles; when the tail liquid in the liquid medicine buffer tank is less than the sum of the target filling volumes of the next batch of bottles, the second filling device (4) in step S7 gradually reduces the number of filling pumps involved in the filling.
5. The filling method according to any one of claims 1 to 4, characterized in that: The set filling volume for the first filling in step S2 is 0.8K-0.95K.