Filling system and filling method

Abstract

The present invention discloses a filling system, including a medicine supply device, a liquid inlet valve, a buffer tank, a liquid dispensing device, a plurality of filling needles arranged side by side, and a liquid replenishing device for replenishing liquid to medicine bottles whose medicine loading amount does not meet the standard, the medicine supply device and the buffer tank are connected through the liquid inlet valve, the buffer tank and the liquid inlet of the liquid dispensing device are connected through a pipeline, a plurality of liquid outlets are arranged at the bottom of the liquid dispensing device along the length direction, each liquid outlet is connected to each filling needle through a filling pump, the liquid replenishing device includes a liquid replenishing needle and a liquid replenishing pump, and the liquid replenishing needle is connected to the liquid dispensing device through the liquid replenishing pump. The present invention also discloses a filling method, which is carried out by using a filling system, and includes the steps: S1: weighing before the medicine bottle; S2: emptying before normal filling; S3: weighing and replenishing liquid after the medicine bottle; S4: normal filling and replenishing liquid; S5: filling of tail liquid. The filling system and the filling method have the advantages of being able to improve the filling accuracy and reduce the waste of liquid medicine.

Description

Technical Field

[0001] The present invention relates to the technical field of food and medicine packaging machinery and equipment, and in particular to a filling system and a filling method. Background Art

[0002] The existing liquid medicine filling system will scrap the liquid medicine filled in the emptying stage before normal production, the liquid medicine filled unqualified during the production process, the liquid medicine filled unqualified during the tail liquid filling stage at the end of production, and the liquid medicine that cannot be completely filled into the silicone tube, resulting in a large amount of liquid medicine wasted. Especially for high value-added products, each production batch directly loses tens of thousands or even hundreds of thousands.

[0003] The liquid inlet of the liquid dispensing device of the existing filling system is set at the center of one end of the liquid dispensing device, so that the gas in the liquid dispensing device cannot be completely discharged during the emptying process before filling, thereby affecting the filling accuracy. In addition, the liquid dispensing device of the existing filling system is set horizontally, that is, the liquid outlets of each liquid dispensing device are on the same horizontal plane, so that a part of the liquid medicine will always remain in the liquid dispensing device, resulting in waste of liquid medicine.

[0004] The existing filling system gas exhaust method is to manually operate the liquid medicine. The liquid separator is installed horizontally, and the control valve of the liquid medicine is not intermittently controlled, resulting in a lot of gas remaining in the liquid separator. The liquid separator needs to be turned over to exhaust the gas. The whole operation is complicated, and it is impossible to ensure that all small bubbles in the liquid separator are completely discharged, resulting in the possibility that the residual bubbles enter the filling pipeline during the filling process, affecting the precision control of the filling amount. In the prior art, the manual mode operation equipment control system controls the pump to suck and empty the bubbles in the liquid separator and the filling pipeline, but the operation of each person cannot be reproduced, and the efficiency is very low, which will also lead to a lot of liquid medicine waste.

[0005] The number of existing filling needles for tail material filling is fixed. The number of filling needles cannot be adjusted during tail material filling, so neither decreasing filling nor single-needle filling can be achieved. As a result, when filling tail materials, multiple bottles must be filled with the original number of filling needles at the same time. When filling tail liquid, due to insufficient amount of medicine liquid in the buffer filling, the filling amount of medicine liquid in multiple bottle containers is unqualified and must be discarded, resulting in waste of medicine liquid. Summary of the invention

[0006] The technical problem to be solved by the present invention is to overcome the deficiencies of the prior art and provide a filling system and a filling method which can improve the filling accuracy and reduce the waste of liquid medicine.

[0007] In order to solve the above technical problems, the present invention adopts the following technical solutions:

[0008] A filling system, comprising a medicine supply device, a liquid inlet valve, a buffer tank, a liquid dispensing device, a plurality of filling needles arranged side by side, a liquid replenishment control unit and a liquid replenishment device for replenishing liquid to a medicine bottle whose medicine filling amount does not meet the standard, wherein the medicine supply device and the buffer tank are connected through a liquid inlet pipeline, the liquid inlet pipeline is provided with a liquid inlet valve, the buffer tank is connected to the liquid inlet of the liquid dispensing device through a first pipeline, the bottom of the liquid dispensing device is provided with a plurality of liquid outlets along the length direction, each of the liquid outlets is connected to each filling needle through a second pipeline, and each of the second pipelines is provided with a filling pump The fluid replenishment device includes a fluid replenishment needle and a fluid replenishment pump, the fluid replenishment needle is connected to the liquid dispensing device through the fluid replenishment pump, the fluid replenishment control unit includes a fluid replenishment control module, a first sensor for weighing the weight of an empty bottle, and a second sensor for weighing the weight of a total bottle filled with liquid medicine, the first sensor, the second sensor, and the fluid replenishment pump are respectively connected to the fluid replenishment control module signal, the fluid replenishment control module calculates the amount of medicine in the medicine bottle according to the received weight signal, and when the amount of medicine in the medicine bottle does not meet the standard, the fluid replenishment control module starts the fluid replenishment pump to replenish the medicine bottle.

[0009] As a further improvement of the above technical solution:

[0010] The liquid replenishment control unit further comprises a filling volume calibration module for calibrating the filling volume of the filling pump, and the first sensor, the second sensor and the filling pump are respectively connected to the filling volume calibration module by signals.

[0011] The liquid inlet is arranged on the top of the liquid separation device.

[0012] The bottom of the liquid separation device is arranged inclined.

[0013] The inclination angle a of the bottom of the liquid separation device is 3° to 7°.

[0014] The liquid inlet is eccentrically arranged at one end of the liquid separation device.

[0015] The filling system further comprises a third sensor for weighing the real-time weight of the buffer tank and a calculation module for calculating the amount of the liquid medicine in the liquid dispensing device, and the third sensor is connected to the calculation module by signal.

[0016] A filling method, using the above filling system, comprises the following steps:

[0017] S1: Weighing before medicine bottle: The first sensor weighs the weight of the empty bottle and transmits the empty bottle weight signal to the rehydration control module;

[0018] S2: Emptying before normal filling: inject liquid medicine into the filling system until the gas in the first pipeline, the liquid dispensing device and the second pipeline is discharged. At this time, the medicine bottle is partially filled with liquid medicine;

[0019] S3: Weighing and refilling the medicine bottle: The second sensor weighs the total weight of the bottle filled with part of the medicine liquid, and transmits the total bottle weight signal to the refill control module. The refill control module calculates the amount of medicine in the medicine bottle according to the received weight signal. If the amount of medicine in the medicine bottle does not meet the standard, the refill control module starts the refill pump to refill the medicine bottle until the amount of medicine in the medicine bottle meets the standard.

[0020] S4: normal filling and fluid replenishment: execute step S1, start each filling pump for normal filling and step S3 in sequence;

[0021] S5: Tail liquid filling: When the liquid level in the buffer tank reaches the specified liquid level at the bottom, the amount of liquid medicine in the liquid separation device is measured in real time; when the amount of liquid medicine in the liquid separation device reaches a first predetermined value, the number of filling needles is gradually reduced as the amount of liquid medicine in the liquid separation device decreases; when the amount of liquid medicine in the liquid separation device reaches a second predetermined value that is less than the first predetermined value, a single filling needle is used for filling.

[0022] As a further improvement of the above technical solution:

[0023] In step S2, first, the liquid inlet valve is opened intermittently to intermittently inject liquid medicine into the liquid separation device until the liquid separation device is filled with liquid medicine and the gas in the liquid separation device is discharged along the first pipeline; then, each filling pump is turned on to discharge the gas in each second pipeline through the filling needle.

[0024] Before normal filling, the filling volume of each filling pump is calibrated, the medicine bottles under each filling needle are weighed, and the weighing deviation of each medicine bottle before and after filling is measured, and then it is determined whether the weighing deviation is qualified. If the weighing deviation of each medicine bottle is qualified, normal filling production is carried out. If there is any unqualified, the filling volume of the corresponding filling pump is adjusted until the weighing deviation of each medicine bottle is qualified.

[0025] Compared with the prior art, the advantages of the present invention are:

[0026] The filling system of the present invention comprises a medicine supply device, a liquid inlet valve, a buffer tank, a liquid separation device, a plurality of filling needles arranged side by side, and a liquid replenishing device for replenishing liquid in medicine bottles whose medicine filling amounts do not meet the standards. The medicine supply device and the buffer tank are connected through the liquid inlet valve, the buffer tank and the liquid inlet of the liquid separation device are connected through a pipeline, a plurality of liquid outlets are arranged at the bottom of the liquid separation device along the length direction, each liquid outlet is connected to each filling needle through a filling pump respectively, the liquid replenishing device comprises a liquid replenishing needle and a liquid replenishing pump, and the liquid replenishing needle is connected to the liquid separation device through the liquid replenishing pump. The medicine bottles filled in the emptying stage before normal production generally fail to reach the qualified amount of medicine. The difference in the medicine bottle is calculated by the rehydration control module of the rehydration control unit, and then the rehydration control module starts the rehydration pump to rehydrate the medicine bottle until the difference is made up, so that the medicine bottle becomes a qualified product, thereby reducing the waste of liquid medicine in the emptying stage; similarly, the rehydration control unit can rehydrate the medicine bottles filled with unqualified amounts of medicine during the production process, so that the medicine bottles become qualified products, thereby reducing the waste of liquid medicine in the production process; similarly, the rehydration control unit can rehydrate the medicine bottles filled with unqualified amounts of medicine in the tail liquid filling stage at the end of production, so that the medicine bottles become qualified products, thereby reducing the waste of liquid medicine in the tail liquid filling stage. The rehydration control unit can rehydrate the medicine bottles filled in the emptying stage before normal production, the medicine bottles filled with unqualified amounts of medicine during the production process, and the medicine bottles filled with unqualified amounts of medicine in the tail liquid filling stage at the end of production until they are qualified, greatly reducing the waste of liquid medicine and reducing production costs. Since the infusion needle of the infusion device is connected to the liquid dispensing device through the infusion pump, the residual medicine amount in the liquid dispensing device and each pipeline can be reduced during the tail liquid filling stage, further reducing the waste of medicine liquid.

[0027] The filling method of the present invention is carried out by using a filling system, and comprises the following steps: S1: weighing before medicine bottles: a first sensor weighs the weight of an empty bottle, and transmits the empty bottle weight signal to a liquid replenishment control module; S2: emptying before normal filling: injecting liquid medicine into the filling system until the gas in the first pipeline, the liquid separation device and the second pipeline is discharged, at which time the medicine bottles are partially filled with liquid medicine; S3: weighing and replenishing medicine bottles after medicine bottles: a second sensor weighs the total weight of the bottles filled with partially liquid medicine, and transmits the total bottle weight signal to the liquid replenishment control module, the liquid replenishment control module calculates the amount of medicine in the medicine bottles according to the received weight signal, and if the medicine If the amount of medicine in the bottle does not meet the standard, the rehydration control module starts the rehydration pump to replenish the bottle until the amount of medicine in the bottle meets the standard; S4: normal filling, rehydration: execute step S1, start each filling pump for normal filling and step S3 in sequence; S5: tail liquid filling: when the liquid level in the buffer tank reaches the specified liquid level at the bottom, measure the amount of liquid medicine in the liquid separation device in real time; when the amount of liquid medicine in the liquid separation device is the first predetermined value, the number of filling needles is gradually reduced as the amount of liquid medicine in the liquid separation device decreases; when the amount of liquid medicine in the liquid separation device is the second predetermined value less than the first predetermined value, a single filling needle is used for filling. This filling method can replenish the liquid medicine bottles filled in the emptying stage before normal production, the bottles filled with unqualified amounts of medicine during the production process, and the bottles filled with unqualified amounts of medicine in the tail liquid filling stage at the end of production until they meet the standard, which greatly reduces the waste of liquid medicine and reduces production costs. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] Figure 1 It is a structural schematic diagram of the filling system of the present invention.

[0029] Figure 2 It is a structural schematic diagram of the liquid separation device of the filling system of the present invention.

[0030] Figure 3 yes Figure 2 Enlarged view of point A in the middle.

[0031] Figure 4 It is a structural schematic diagram of the liquid inlet of the liquid dispensing device of the filling system of the present invention.

[0032] The symbols in the figure represent:

[0033] 1. Drug supply device; 2. Liquid inlet valve; 3. Buffer tank; 31. Third sensor; 4. Liquid dispensing device; 41. Liquid inlet; 42. Liquid outlet; 5. Filling needle; 6. First pipeline; 7. Second pipeline; 71. Filling pump; 8. Liquid replenishment control unit; 81. First sensor; 82. Second sensor; 9. Liquid replenishment device; 91. Liquid replenishment needle; 92. Liquid replenishment pump. DETAILED DESCRIPTION

[0034] The present invention will be further described in detail below with reference to the accompanying drawings and specific embodiments.

[0035] Figures 1 to 4 An embodiment of the filling system of the present invention is shown, which includes a drug supply device 1, a liquid inlet valve 2, a buffer tank 3, a liquid dispensing device 4, a plurality of filling needles 5 arranged side by side, a liquid replenishment control unit 8 and a liquid replenishment device 9 for replenishing liquid to a medicine bottle whose drug filling amount does not meet the standard. The drug supply device 1 and the buffer tank 3 are connected through a liquid inlet pipeline, and a liquid inlet valve 2 is arranged on the liquid inlet pipeline. The buffer tank 3 is connected to a liquid inlet 41 of the liquid dispensing device 4 through a first pipeline 6. A plurality of liquid outlets 42 are arranged at the bottom of the liquid dispensing device 4 along the length direction. Each liquid outlet 42 is connected to each filling needle 5 through a second pipeline 7, and each second pipeline 7 has a liquid outlet 42 disposed thereon. A filling pump 71 is provided, and the fluid replenishment device 9 includes a fluid replenishment needle 91 and a fluid replenishment pump 92. The fluid replenishment needle 91 is connected to the liquid dispensing device 4 through the fluid replenishment pump 92. The fluid replenishment control unit 8 includes a fluid replenishment control module, a first sensor 81 for weighing the weight of an empty bottle, and a second sensor 82 for weighing the weight of a total bottle filled with liquid medicine. The first sensor 81, the second sensor 82, and the fluid replenishment pump 92 are respectively connected to the fluid replenishment control module signal. The fluid replenishment control module calculates the amount of medicine in the medicine bottle according to the received weight signal. When the amount of medicine in the medicine bottle does not meet the standard, the fluid replenishment control module starts the fluid replenishment pump 92 to replenish the medicine bottle.

[0036] The medicine bottles filled in the emptying stage before normal production generally fail to reach the qualified amount of medicine. The difference in the medicine bottle is calculated by the liquid replenishment control module of the liquid replenishment control unit 8, and then the liquid replenishment control module starts the liquid replenishment pump 92 to replenish the medicine bottle until the difference is replenished, so that the medicine bottle becomes a qualified product, thereby reducing the waste of liquid medicine in the emptying stage; similarly, the liquid replenishment control unit 8 can replenish the medicine bottles filled with unqualified amounts of medicine during the production process, so that the medicine bottles become qualified products, thereby reducing the waste of liquid medicine in the production process; similarly, the liquid replenishment control unit 8 can replenish the medicine bottles filled with unqualified amounts of medicine in the tail liquid filling stage at the end of production, so that the medicine bottles become qualified products, thereby reducing the waste of liquid medicine in the tail liquid filling stage. The liquid replenishment control unit 8 can replenish the medicine bottles filled in the emptying stage before normal production, the medicine bottles filled with unqualified amounts of medicine during the production process, and the medicine bottles filled with unqualified amounts of medicine in the tail liquid filling stage at the end of production until they are qualified, greatly reducing the waste of liquid medicine and reducing production costs. Since the infusion needle 91 of the infusion device 9 is connected to the liquid dispensing device 4 via the infusion pump 92, the residual medicine amount in the liquid dispensing device 4 and each pipeline can be reduced during the tail liquid filling stage, further reducing the waste of medicine liquid.

[0037] In this embodiment, the liquid replenishment control unit 8 also includes a filling quantity calibration module for calibrating the filling quantity of the filling pump 71. The first sensor 81, the second sensor 82, and the filling pump 71 are respectively connected to the filling quantity calibration module signal. The first sensor 81 weighs the weight of each empty bottle and sends the weight signal of each empty bottle to the filling quantity calibration module. The second sensor 82 weighs the total weight of each bottle filled with liquid medicine and sends the weight signal of each total bottle to the filling quantity calibration module. The filling quantity calibration module calculates the weight deviation of each medicine bottle according to the received signal, and then measures the filling pump 71 with unqualified filling quantity according to the weight deviation, and adjusts the unqualified filling pump 71 to qualified. The filling quantity calibration module can calibrate the filling quantity of the filling pump 71 so that the filling pump 71 can meet the filling requirements and improve the filling accuracy and production efficiency.

[0038] In this embodiment, Figures 1 to 4 As shown, the liquid inlet 41 is arranged at the top of the liquid separator 4. Since the liquid inlet 41 is arranged at the top of the liquid separator 4, before filling, the liquid separator 4 and the first pipeline 6 between the liquid separator 4 and the buffer tank 3 can be completely emptied by intermittently opening the liquid inlet valve 2 (intermittently opening the liquid inlet valve 2 can intermittently inject liquid medicine into the buffer tank 3, so that the first pipeline 6 between the liquid separator 4 and the buffer tank 3 is intermittently empty, which is convenient for the gas in the buffer tank 3 to be discharged). This is convenient for accurate calculation of the subsequent filling amount, improves the filling accuracy, and avoids repeated filling due to unqualified filling accuracy, thereby avoiding a large amount of liquid medicine waste.

[0039] In this embodiment, Figure 1 As shown, the bottom of the liquid separation device 4 is tilted. The liquid inlet 41 is eccentrically arranged at the upper end of the liquid separation device 4 (such as Figure 1 and Figure 3 As shown in the figure, when the liquid dispensing device 4 is filling the tail liquid, the amount of the filling needle 5 can be adjusted according to the amount of liquid medicine in the liquid dispensing device 4, until the single filling needle 5 corresponding to the bottom liquid outlet 42 of the liquid dispensing device 4 is used for filling, so that the last bottle of medicine is filled, thereby reducing the amount of liquid medicine remaining in the liquid dispensing device 4. The inclination angle a at the bottom of the liquid dispensing device 4 is preferably selected to be 3° to 7°.

[0040] In this embodiment, Figure 1 As shown, the filling system further includes a third sensor 31 for weighing the real-time weight of the buffer tank 3 and a calculation module for calculating the amount of liquid medicine in the liquid dispensing device 4, and the third sensor 31 is connected to the calculation module by signal. The third sensor 31 weighs the real-time weight of the buffer tank 3 and sends the real-time weight signal to the calculation module, and the calculation module calculates the amount of liquid medicine in the liquid dispensing device 4 according to the received signal, so as to facilitate the selection of the amount of the filling needle 5 to be used.

[0041] A filling method, using a filling system, comprises the following steps:

[0042] S1: Weighing before the medicine bottle: The first sensor 81 weighs the weight of the empty bottle and transmits the empty bottle weight signal to the liquid replenishment control module;

[0043] S2: Emptying before normal filling: injecting liquid medicine into the filling system until the gas in the first pipeline 6, the liquid separation device 4 and the second pipeline 7 is discharged, at which time the medicine bottle is partially filled with liquid medicine;

[0044] S3: Weighing and refilling the medicine bottle: The second sensor 82 weighs the total weight of the bottle filled with a portion of the medicine liquid, and transmits the total bottle weight signal to the refill control module. The refill control module calculates the amount of medicine in the medicine bottle according to the received weight signal. If the amount of medicine in the medicine bottle does not meet the standard, the refill control module starts the refill pump 92 to refill the medicine bottle until the amount of medicine in the medicine bottle meets the standard.

[0045] S4: normal filling and fluid replenishment: execute step S1 in sequence, start each filling pump 71 to perform normal filling and step S3;

[0046] S5: Tail liquid filling: When the liquid level in the buffer tank 3 reaches the specified liquid level at the bottom, the amount of liquid medicine in the liquid separation device 4 is measured in real time; when the amount of liquid medicine in the liquid separation device 4 reaches a first predetermined value, the number of filling needles 5 is gradually reduced as the amount of liquid medicine in the liquid separation device 4 decreases; when the amount of liquid medicine in the liquid separation device 4 reaches a second predetermined value that is less than the first predetermined value, a single filling needle 5 is used for filling.

[0047] This filling method can replenish liquid to medicine bottles filled in the emptying stage before normal production, medicine bottles filled with unqualified medicine quantities during the production process, and medicine bottles filled with unqualified medicine quantities in the tail liquid filling stage at the end of production, until they are qualified, thereby greatly reducing the waste of medicine liquid and reducing production costs.

[0048] In this embodiment, in step S2, first, the liquid inlet valve 2 is intermittently opened to intermittently inject liquid medicine into the liquid separation device 4 until the liquid separation device 4 is full of liquid medicine and the gas in the liquid separation device 4 is discharged along the first pipeline 6; then, each filling pump 71 is turned on to discharge the gas in each second pipeline 7 through the filling needle 5. Specifically, the liquid inlet valve 2 is intermittently opened to intermittently inject liquid medicine into the buffer tank 3, such as opening the liquid inlet valve 2 to inject liquid medicine into the buffer tank 3, and the liquid medicine in the buffer tank 3 enters the liquid separation device 4 through the first pipeline 6; the liquid inlet valve 2 is closed, and part of the gas in the liquid separation device 4 is discharged into the buffer tank 3 through the first pipeline 6. In this way, by opening the liquid inlet valve 2 intermittently for multiple times, the liquid separation device 4 and the first pipeline 6 can be filled with liquid medicine, and the gas in the liquid separation device 4 and the first pipeline 6 can be discharged, which is convenient for the accurate calculation of the filling amount in each subsequent medicine bottle, improves the filling accuracy, and avoids a large number of unqualified waste products caused by unqualified filling accuracy, thereby causing a large amount of liquid medicine waste.

[0049] In this embodiment, the filling amount of each filling pump 71 is calibrated before normal filling, the medicine bottles under each filling needle 5 are weighed, and the weighing deviation of each medicine bottle before and after filling is measured, and then it is determined whether the weighing deviation is qualified. If the weighing deviation of each medicine bottle is qualified, normal filling production is carried out. If there is any unqualified, the filling amount of the corresponding filling pump 71 is adjusted until the weighing deviation of each medicine bottle is qualified.

[0050] For example: take the KGSA12 filling machine filling 2ml of a 2ml vial as an example, there are a total of 12 filling needles 5, which are recorded as No. 1 to 12 in the conveying direction of the medicine bottle. First, select the first group of six medicine bottles for pre-weighing, and then put the first group of six medicine bottles directly under the filling needles 5 of No. 1 to 6, and automatically start the filling pumps 71 corresponding to the filling needles 5 of No. 1 to 6 for the first emptying. The liquid in each of the six medicine bottles is about 1.5ml, and then each medicine bottle is post-weighed. After the amount of liquid medicine is weighed out according to the post-weighing, the liquid replenishment control unit 8 directly above the medicine bottle is used to fill and weigh the medicine bottle until the medicine bottle reaches the qualified amount of liquid medicine; then enter the second group of six medicine bottles corresponding to the filling needles 5 of No. 7 to 12, and run according to the process of the previous group to ensure that the amount of liquid medicine is qualified. Press it, and then enter the third group of six medicine bottles of filling needles 5 No. 1 to 6, carry out pre-weighing, and then put the third group of six medicine bottles directly under the filling needles 5 No. 1 to 6, and each filling pump 71 accurately fills 2ml of the filling volume, and then each medicine bottle is weighed afterward. If the medicine liquid filling volume is unqualified, the medicine bottle will be weighed while filling through the rehydration needle 91 and the rehydration control module of the rehydration control unit 8 directly above the medicine bottle until the medicine bottle reaches the qualified medicine liquid filling volume; then run the fourth group of six medicine bottles corresponding to the filling needles 5 No. 7 to 12, and run according to the process of the previous group to ensure that the medicine liquid filling volume is qualified. If the liquid filling amount of the 12 medicine bottles in the third and fourth groups all pass the first filling, the normal filling (normal sampling and weighing production mode) will be entered; if the filling amount of the 12 medicine bottles in the third and fourth groups is unqualified in one filling, the above process will be followed for another 12 bottles (6 bottles in each group). If the liquid filling amount of the 12 medicine bottles in the third and fourth groups all pass the first filling, the normal filling will be automatically entered. If there are still medicine bottles with unqualified liquid filling amount, the filling pump 71 will be calibrated according to the results of the two weighings, and then a group of 12 medicine bottles will be fully weighed. If all are qualified, the normal filling will be automatically entered.

[0051] During the normal filling production process, after the amount of the medicine liquid is weighed out, if it is found to be unqualified, the medicine bottle will be weighed while filling through the refilling needle 91 and the refilling control module of the refilling control unit 8 just above the medicine bottle until the medicine bottle reaches the qualified amount of medicine liquid; then the 100% weighing mode will be enabled to calibrate the filling amount of the filling pump 71, and normal filling will be carried out after the filling amount of the entire group is qualified.

[0052] When the third sensor 31 of the buffer tank 3 detects that the liquid is not replenished, the tail liquid filling is carried out: using filling needles 5 No. 1 to 12 (the higher the number of the filling needle 5, the lower the position at which it is connected to the liquid dispensing device 4) to fill for several cycles according to the number of groups set in the recipe parameters, when the amount of liquid in the liquid dispensing device 4 reaches the first predetermined value (50% of the capacity of the liquid dispensing device 4), switch to the low-position filling needles 1 to 6 for filling, when weighing detects that the filling pump 71 corresponding to the filling needles 1 to 6 is unqualified, the filling of the filling needles 1 to 6 is automatically stopped, and the filling of the filling needles 7 to 12 is adopted, and when the amount of liquid in the liquid dispensing device 4 reaches the second predetermined value (20% of the capacity of the liquid dispensing device 4), the filling needle 12 is adopted. Specifically, first, filling needles 5 of No. 1 to 6 are used for filling, and several cycles are performed until all the liquid medicine in the second pipeline 7 is injected into the lower medicine bottle, and then the liquid is replenished through the liquid replenishing needle 91 until it is qualified, and then filling needles 5 of No. 7-9 are operated according to the previous step to fill, until all the liquid medicine in the corresponding second pipeline 7 is injected into the lower medicine bottle, and then the liquid is replenished through the liquid replenishing needle 91 until it is qualified; then filling needles 5 of No. 10-12 are operated according to the previous step to fill, until all the liquid medicine in the corresponding second pipeline 7 is injected into the lower medicine bottle, and then the liquid is replenished through the liquid replenishing needle 91 until it is qualified; finally, filling needle No. 12 on the rear weighing station is used to perform weighing while filling, and when the filling needle 5 finally fills all the liquid medicine in the dispenser, the filling process is automatically terminated until the detection of unqualified filling volume.

[0053] Although the present invention has been disclosed as above with preferred embodiments, it is not intended to limit the present invention. Any technician familiar with the art can make many possible changes and modifications to the technical solution of the present invention by using the technical content disclosed above without departing from the scope of the technical solution of the present invention, or modify it into an equivalent embodiment of equivalent changes. Therefore, any simple modification, equivalent change and modification made to the above embodiments according to the technical essence of the present invention without departing from the content of the technical solution of the present invention should fall within the scope of protection of the technical solution of the present invention.

Claims

1. A filling system, characterized in that: The invention comprises a medicine supply device (1), a liquid inlet valve (2), a buffer tank (3), a liquid separation device (4), a plurality of filling needles (5) arranged side by side, a liquid replenishment control unit (8) and a liquid replenishment device (9) for replenishing liquid to a medicine bottle whose medicine filling amount does not meet the standard, wherein the medicine supply device (1) and the buffer tank (3) are connected via a liquid inlet pipeline, the liquid inlet pipeline is provided with a liquid inlet valve (2), the buffer tank (3) is connected to a liquid inlet (41) of the liquid separation device (4) via a first pipeline (6), a plurality of liquid outlets (42) are provided at the bottom of the liquid separation device (4) along the length direction, each of the liquid outlets (42) is connected to each filling needle (5) via a second pipeline (7), each of the second pipelines (7) is provided with a filling pump (71), and the The rehydration device (9) comprises a rehydration needle (91) and a rehydration pump (92), wherein the rehydration needle (91) is connected to the liquid dispensing device (4) via the rehydration pump (92), and the rehydration control unit (8) comprises a rehydration control module, a first sensor (81) for weighing the weight of an empty bottle, and a second sensor (82) for weighing the weight of a total bottle filled with liquid medicine, wherein the first sensor (81), the second sensor (82), and the rehydration pump (92) are respectively connected to the rehydration control module by signal, and the rehydration control module calculates the amount of medicine in the medicine bottle according to the received weight signal, and when the amount of medicine in the medicine bottle does not meet the standard in the pre-production emptying stage and / or the tail liquid filling stage, the rehydration control module starts the rehydration pump (92) to replenish the medicine bottle with liquid.

2. The filling system according to claim 1, characterized in that: The liquid replenishment control unit (8) further comprises a filling volume calibration module for calibrating the filling volume of the filling pump (71), and the first sensor (81), the second sensor (82) and the filling pump (71) are respectively connected to the filling volume calibration module by signals.

3. The filling system according to claim 1, characterized in that: The liquid inlet (41) is arranged at the top of the liquid separation device (4).

4. The filling system according to claim 1, characterized in that: The bottom of the liquid separation device (4) is arranged inclined.

5. The filling system according to claim 4, characterized in that: The inclination angle a of the bottom of the liquid separation device (4) is 3° to 7°.

6. The filling system according to claim 1, characterized in that: The liquid inlet (41) is eccentrically arranged at one end of the liquid separation device (4).

7. The filling system according to any one of claims 1 to 6, characterized in that: The filling system further comprises a third sensor (31) for measuring the real-time weight of the buffer tank (3) and a calculation module for calculating the amount of the medicinal liquid in the liquid dispensing device (4), and the third sensor (31) is signal-connected to the calculation module.

8. A filling method, characterized in that: The method is carried out using the filling system according to any one of claims 1 to 7, comprising the following steps: S1: Weighing the medicine bottle: The first sensor (81) weighs the weight of the empty bottle and transmits the empty bottle weight signal to the liquid replenishment control module; S2: Emptying before normal filling: injecting liquid medicine into the filling system until the gas in the first pipeline (6), the liquid separation device (4) and the second pipeline (7) is discharged, at which time the medicine bottle is partially filled with liquid medicine; S3: Weighing and refilling the medicine bottle: The second sensor (82) weighs the total weight of the bottle filled with a portion of the medicine liquid, and transmits the total bottle weight signal to the refill control module. The refill control module calculates the amount of medicine in the medicine bottle according to the received weight signal. If the amount of medicine in the medicine bottle does not meet the standard, the refill control module starts the refill pump (92) to refill the medicine bottle until the amount of medicine in the medicine bottle meets the standard. S4: normal filling and fluid replenishment: sequentially executing step S1, starting each filling pump (71) for normal filling and step S3; S5: Tail liquid filling: When the liquid level in the buffer tank (3) reaches the designated liquid level at the bottom, the amount of liquid medicine in the liquid separation device (4) is measured in real time; when the amount of liquid medicine in the liquid separation device (4) reaches a first predetermined value, the number of filling needles (5) is gradually reduced as the amount of liquid medicine in the liquid separation device (4) decreases; when the amount of liquid medicine in the liquid separation device (4) reaches a second predetermined value that is smaller than the first predetermined value, a single filling needle (5) is used for filling.

9. The filling method according to claim 8, characterized in that: In the step S2, first, the liquid inlet valve (2) is opened intermittently to intermittently inject liquid medicine into the liquid separation device (4) until the liquid separation device (4) is filled with liquid medicine and the gas in the liquid separation device (4) is discharged along the first pipeline (6); then, each filling pump (71) is turned on to discharge the gas in each second pipeline (7) through the filling needle (5).

10. The filling method according to claim 8, characterized in that: Before normal filling, the filling amount of each filling pump (71) is calibrated, and the medicine bottles under each filling needle (5) are weighed, and the weighing deviation of each medicine bottle before and after filling is measured, and then it is determined whether the weighing deviation is qualified. If the weighing deviation of each medicine bottle is qualified, normal filling production is carried out. If there is an unqualified, the filling amount of the corresponding filling pump (71) is adjusted until the weighing deviation of each medicine bottle is qualified.

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