A tissue slicing device capable of continuous slicing

Abstract

The present invention provides a tissue slicing device capable of continuous slicing, and belongs to the technical field of laboratory tools. The device comprises a tubular body and a mounting through hole located in the body, the two ends of the mounting through hole are respectively a feed port and a discharge port, two groups of clip assemblies are arranged in the mounting through hole, the clip assemblies comprise a control wheel located at the feed port, a positioning wheel and a shape-keeping wheel located at the discharge port, a traction belt is connected between the control wheel, the positioning wheel and the shape-keeping wheel, the straight section of the traction belt close to the middle of the mounting through hole is a clamping section, the straight section of the traction belt close to the discharge port is a positioning section, a conveying channel for clamping the sample is formed between the two clamping sections, the two straight sections are parallel to each other, a synchronous gear is fixedly arranged on each of the two control wheels, the two synchronous gears are meshed with each other, and a hand wheel extending out of the body is fixedly arranged on one of the control wheels. The present invention has the advantages of being able to perform continuous slicing according to thickness requirements.

Description

Technical Field

[0001] The invention belongs to the technical field of laboratory tools and relates to a tissue slicing device capable of continuous slicing. Background Art

[0002] When observing the tissue structure of biological samples through a microscope, the biological tissue needs to be sliced ​​and then pasted (sometimes stained) to make glass slides for microscopic observation. The thickness of the tissue slices is at the micron level. Manual slicing is not only difficult to control the thickness and inconvenient to operate, but also poses a safety hazard.

[0003] In the prior art, paraffin sectioning is usually used for better sectioning, but the process is complicated, especially in summer, paraffin is easy to soften and needs to be frozen and then quickly processed, which seriously affects the portability of the sectioning, especially when students in the laboratory perform related operations, there is great inconvenience.

[0004] Chinese patent [CN201220174870.7] discloses a brain tissue slicing tool with high slicing efficiency and precise thickness, including a fixed frame, studs passing through both sides of the frame, multiple blades passing through the studs, and gaskets arranged between adjacent blades.

[0005] In this solution, a tissue sample is cut at one time by means of multiple blades. However, this solution not only has low sample positioning accuracy and complicated positioning operation, but also cannot be sliced ​​continuously. Multi-blade cutting cannot meet the needs of slices of different thicknesses. Summary of the invention

[0006] The purpose of the present invention is to provide a tissue slicing device capable of continuous slicing in view of the above-mentioned problems existing in the prior art. The technical problem to be solved by the present invention is how to achieve continuous slicing under the premise that the thickness of the sample can be controlled.

[0007] The objective of the present invention can be achieved through the following technical solutions: A tissue slicing device capable of continuous slicing, characterized in that it comprises a tubular body and a mounting through hole in the body, the two ends of the mounting through hole being an inlet and an outlet respectively, two sets of clip assemblies are arranged in the mounting through hole, the clip assembly comprises a control wheel at the inlet, a positioning wheel and a shape-keeping wheel at the outlet, a traction belt is connected among the control wheel, the positioning wheel and the shape-keeping wheel, the straight section of the traction belt close to the middle of the mounting through hole is a clamping section, the straight section of the traction belt close to the outlet is a positioning section, a conveying channel for clamping the sample is formed between the two clamping sections, the two straight sections are parallel to each other, a synchronous gear is fixedly arranged on each of the two control wheels, the two synchronous gears are meshed with each other, and a handwheel extending out of the body is fixedly arranged on one of the control wheels.

[0008] Furthermore, a cutting assembly is provided at the discharge port, and the positioning sections of the two clip assemblies are on the same plane. The cutting assembly includes two slide grooves opened on the main body and two sliders sliding in the two slide grooves respectively. The slide groove is L-shaped, and the outer ends of the two sliders are connected to a push rod. A blade is connected between the inner ends of the two sliders, and the blade is close to the outer side surface of the straight section of the traction belt. The slide groove is parallel to the plane where the straight section is located.

[0009] Furthermore, the length direction of the slide groove is parallel to the axis of the positioning wheel.

[0010] Furthermore, the control wheel, the positioning wheel and the shape-preserving wheel all have a contraction portion in the middle.

[0011] Furthermore, the hand wheel has a scale, and the body has a reference identification symbol corresponding to the scale.

[0012] Furthermore, the cross section of the body is rectangular.

[0013] Furthermore, the outer side surface of the traction belt has a plurality of transversely arranged limiting ribs, and the traction belt is made of silicone material.

[0014] The L-shaped slide groove refers to a structure with two mutually perpendicular guide grooves, one of which runs through the end face of the body for guiding and positioning the slider, and the other runs through the inner wall of the mounting through hole for guiding and positioning the blade.

[0015] The slicing process is as follows: put the sample into the feed port, push and turn the hand wheel to squeeze the sample into the conveying channel formed by the straight sections of the two traction belts, observe the sample extension at the discharge port, and after the sample extends a little, read the scale and push the blade to cut off and discard the extended part of the sample, and restore the position of the blade; continue to push the hand wheel to rotate the angle required for slicing, and continue to push the blade to cut the extended part of the sample. The tissue slice cut out at this time is the tissue slice of the target thickness. Repeat the above operation to achieve continuous slicing, and the cutting thickness can be adjusted each time.

[0016] If it is necessary to cut stem samples, the stem samples can be clamped by controlling the contraction parts of the rotating wheel, the positioning rotating wheel and the shape-preserving rotating wheel. The pushing and cutting of the samples can be achieved in the same way.

[0017] Since the length direction of the slide is parallel to the axis of the positioning wheel, that is, the cutting direction of the blade moves from one end to the other end of the axis of the positioning wheel, the clamped sample piece is perpendicular to the blade during the cutting process, avoiding the problem of low precision caused by the bending of the sample under force.

[0018] In order to further improve the accuracy, a positioning wheel and a shape-keeping wheel are set so that the traction belt is pulled by the positioning wheel and the shape-keeping wheel with smaller diameter at the discharge port. On the one hand, the length of the sample that cannot be clamped at the discharge port is reduced. On the other hand, the traction belt at the positioning wheel and the shape-keeping wheel, that is, the positioning section is parallel to the blade. The blade is set in a position close to the outer side of the traction belt, so that the slicing error caused by bending deformation of the sample can be reduced when the blade cuts the sample. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a cross-sectional view of the present slicing device.

[0020] Figure 2 It is a three-dimensional structural schematic diagram of the slicing device.

[0021] Figure 3 It is a three-dimensional structural schematic diagram of the control wheel, the positioning wheel and the shape-preserving wheel in the slicing device.

[0022] In the figure, 1, main body; 2, mounting through hole; 31, control wheel; 32, positioning wheel; 33, shape-keeping wheel; 34, contraction part; 4, traction belt; 41, clamping section; 42, positioning section; 51, synchronous gear; 52, hand wheel; 61, slide groove; 62, slider; 63, push rod; 64, blade. DETAILED DESCRIPTION

[0023] The following are specific embodiments of the present invention and the accompanying drawings to further describe the technical solution of the present invention, but the present invention is not limited to these embodiments.

[0024] like Figure 1 and Figure 2 As shown, it includes a tubular body 1 and a mounting through hole 2 located in the body 1, the two ends of the mounting through hole 2 are respectively an inlet and an outlet, two groups of clamping components are arranged in the mounting through hole 2, the clamping component includes a control wheel 31 located at the inlet, a positioning wheel 32 and a shape-keeping wheel 33 located at the outlet, a traction belt 4 is connected among the control wheel 31, the positioning wheel 32 and the shape-keeping wheel 33, a straight section of the traction belt 4 close to the middle of the mounting through hole 2 is a clamping section 41, and a straight section of the traction belt 4 close to the outlet is a positioning section 42, a conveying channel for clamping the sample is formed between the two clamping sections 41, the two straight sections are parallel to each other, a synchronous gear 51 is fixedly provided on each of the two control wheels 31, the two synchronous gears 51 are meshed with each other, and a handwheel 52 extending out of the body 1 is fixedly provided on one of the control wheels 31; the cross-section of the body 1 is rectangular.

[0025] A cutting assembly is provided at the discharge port, and the positioning sections 42 of the two clip assemblies are in the same plane. The cutting assembly includes two slide grooves 61 opened on the main body 1 and two sliders 62 respectively sliding in the two slide grooves 61. The slide groove 61 is L-shaped, and the outer ends of the two sliders 62 are connected to a push rod 63. A blade 64 is connected between the inner ends of the two sliders 62. The blade 64 is close to the outer side surface of the straight section of the traction belt 4. The slide groove 61 is parallel to the plane where the straight section is located; the length direction of the slide groove 61 is parallel to the axis of the positioning wheel 32.

[0026] like Figure 3 As shown, the control wheel 31 , the positioning wheel 32 and the shape-keeping wheel 33 all have a contraction portion 34 in the middle.

[0027] The hand wheel 52 has scales, and the body 1 has reference marks corresponding to the scales. The outer side of the traction belt 4 has a plurality of transversely arranged limit ribs, and the traction belt 4 is made of silicone material.

[0028] The L-shaped slide groove 61 refers to a structure with two mutually perpendicular guide grooves, one of which passes through the end surface of the body 1 for guiding and positioning the slider 62, and the other guide groove passes through the inner wall surface of the mounting hole 2 for guiding and positioning the blade 64.

[0029] The slicing process is as follows: put the sample into the feed port, push and turn the hand wheel 52 to squeeze the sample into the conveying channel formed by the straight sections of the two traction belts 4, observe the protrusion of the sample at the discharge port, and after the sample protrudes a little, read the scale, and push the blade 64 to cut off and discard the protruding part of the sample, and restore the position of the blade 64; continue to push the hand wheel 52 to rotate the angle required for slicing, and continue to push the blade 64 to cut the protruding part of the sample. The tissue slice cut out at this time is the tissue slice of the target thickness. Repeat the above operation to achieve continuous slicing, and the cutting thickness can be adjusted each time slicing.

[0030] If it is necessary to cut the stem samples, the stem samples can be clamped by controlling the contraction part 34 of the rotating wheel 31, the positioning rotating wheel 32 and the shape-preserving rotating wheel 33. The pushing and cutting of the samples can be achieved in the same way.

[0031] Since the length direction of the slide groove 61 is parallel to the axis of the positioning wheel 32, that is, the cutting direction of the blade 64 moves from one end to the other end of the axis of the positioning wheel 32, the clamped sample piece is perpendicular to the blade 64 during the cutting process, avoiding the problem of low precision caused by the bending of the sample under force.

[0032] In order to further improve the accuracy, a positioning wheel 32 and a shape-keeping wheel 33 are set, so that the traction belt 4 is pulled by the positioning wheel 32 and the shape-keeping wheel 33 with smaller diameters at the discharge port. On the one hand, the length of the part of the sample that cannot be clamped at the discharge port is reduced, and on the other hand, the traction belt 4 at the positioning wheel 32 and the shape-keeping wheel 33, that is, the positioning section 42 is parallel to the blade 64, and the blade 64 is set in a position close to the outer side of the traction belt 4, so that the blade 64 can reduce the slicing error caused by bending deformation of the sample when cutting the sample.

[0033] The specific embodiments described herein are merely examples of the spirit of the present invention. Those skilled in the art may make various modifications or additions to the specific embodiments described or replace them in similar ways, but they will not deviate from the spirit of the present invention or exceed the scope defined by the appended claims.

Claims

1. A tissue slicing device capable of continuous slicing, characterized in that: The invention comprises a tubular body (1) and a mounting through hole (2) located in the body (1), wherein the two ends of the mounting through hole (2) are respectively an inlet and an outlet, and two groups of clip assemblies are arranged in the mounting through hole (2), wherein the clip assemblies include a control wheel (31) located at the inlet, a positioning wheel (32) and a shape-preserving wheel (33) located at the outlet, and a traction belt (4) is connected between the control wheel (31), the positioning wheel (32) and the shape-preserving wheel (33). The straight section of the guide belt (4) near the middle of the mounting through hole (2) is the clamping section (41), and the straight section of the traction belt (4) near the discharge port is the positioning section (42). A conveying channel for clamping the sample is formed between the two clamping sections (41). The two straight sections are parallel to each other. A synchronous gear (51) is fixedly provided on each of the two control wheels (31). The two synchronous gears (51) are meshed with each other. A hand wheel (52) extending outside the body (1) is fixedly provided on one of the control wheels (31); A cutting assembly is provided at the discharge port, the positioning sections (42) of the two clip assemblies are on the same plane, the cutting assembly comprises two slide grooves (61) provided on the body (1) and two sliders (62) respectively sliding in the two slide grooves (61), the slide groove (61) is L-shaped, the outer ends of the two sliders (62) are connected to a push rod (63), a blade (64) is connected between the inner ends of the two sliders (62), the blade (64) is closely attached to the outer side surface of the straight section of the traction belt (4), and the slide groove (61) is parallel to the plane where the straight section is located; The control wheel (31), the positioning wheel (32) and the shape-preserving wheel (33) all have a contraction portion (34) in the middle. The hand wheel (52) has a scale, and the body (1) has a reference identification symbol corresponding to the scale; The cross section of the body (1) is rectangular.

2. A tissue slicing device capable of continuous slicing according to claim 1, characterized in that: The length direction of the sliding groove (61) is parallel to the axis of the positioning wheel (32).

3. A tissue slicing device capable of continuous slicing according to claim 1 or 2, characterized in that: The outer side surface of the traction belt (4) has a plurality of transversely arranged limiting ribs, and the traction belt (4) is made of a silicone material.

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