Jaundice detection circuit, jaundice detection device and transcutaneous jaundice tester

By designing a jaundice detection circuit, using the sensor probe and control module to calculate the optical density difference and generating a serum bilirubin concentration value, the problem of inaccurate measurement results and poor consistency of test results of the existing jaundice meter is solved, and a more accurate and consistent test result is achieved. Test results.

CN112472025BActive Publication Date: 2025-01-21JINAN QILI PHOTOELECTRIC TECH CO LTD

Patent Information

Application Number
CN202011197594.1
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2020-10-30
Publication Date
2025-01-21
Estimated Expiration
2040-10-30

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Abstract

The present application belongs to the technical field of jaundice detection, and provides a jaundice detection circuit, a jaundice detection device and a transcutaneous jaundice tester, which receive a detection signal through a sensor probe, emit an incident light signal to the skin surface according to the detection signal, and convert the long light path signal reflected by the skin surface into a long light path electrical signal, and convert the short light path signal reflected by the skin surface into a short light path electrical signal, a control module receives the long light path electrical signal and the short light path signal, obtains an optical density difference according to the long light path electrical signal and the short light path signal, and generates a corresponding serum bilirubin concentration value according to the optical density difference, and a display module displays the serum bilirubin concentration value, thereby solving the problems of inaccurate measurement results and poor consistency of test results existing in current jaundice meters.
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Description

Technical Field

[0001] The present application belongs to the technical field of jaundice detection, and in particular, relates to a jaundice detection circuit, a jaundice detection device and a transcutaneous jaundice tester. Background Art

[0002] Jaundice is a disease that occurs when bilirubin produced by the decomposition of hemoglobin in red blood cells is not discharged from the living body due to some kind of obstacle, and the blood becomes hyperbilirubinemia. The bilirubin in the blood of the hyperbilirubinemia is deposited in the living tissue, thereby causing the living tissue to be yellow. The bilirubin has a high affinity with elastic fibers (elastic fibers), so it is deposited in the skin, sclera (strong membrane) and blood vessels rich in elastic fibers. In addition, since the oxygen exchange of the placenta in the embryonic period is not as efficient as that of the lungs, the number of red blood cells is about 1.5 to 2 times that of adults in order to supplement the insufficient oxygen. If lung breathing can be performed from birth, the red blood cells in the blood become excessive, and the excess red blood cells are decomposed. Therefore, newborns become jaundiced due to such physiological phenomena, and the jaundice is called neonatal jaundice. The neonatal jaundice sometimes develops into a serious disease, and there is a risk of having a significant impact on the life and brain development of the newborn. Therefore, neonatal jaundice needs to be appropriately discovered and treated in the early stage. The intensity of jaundice symptoms (degree of jaundice) should be accurately determined by measuring the bilirubin level in the blood. However, it is difficult and impractical to collect blood from all newborns for measurement. Therefore, an optical jaundice meter is usually used to measure the jaundice level of newborns.

[0003] However, current jaundice meters suffer from inaccurate measurement results and poor consistency in test results. Summary of the invention

[0004] The purpose of the present application is to provide a jaundice detection circuit, a jaundice detection device and a transcutaneous jaundice tester, aiming to solve the problems of inaccurate measurement results and poor consistency of test results existing in current jaundice meters.

[0005] A first aspect of an embodiment of the present application provides a jaundice detection circuit, the jaundice detection circuit comprising:

[0006] A sensor probe, used to receive a detection signal, transmit an incident light signal to a skin surface according to the detection signal, and convert a long light path signal reflected by the skin surface into a long light path electrical signal, and convert a short light path signal reflected by the skin surface into a short light path electrical signal;

[0007] A control module, configured to receive the long optical path electrical signal and the short optical path signal, obtain an optical density difference according to the long optical path electrical signal and the short optical path signal, and generate a corresponding serum bilirubin concentration value according to the optical density difference;

[0008] The display module is connected to the control module and is used to display the serum bilirubin concentration value.

[0009] In one embodiment, the serum bile concentration value is linearly related to the optical density difference.

[0010] In one embodiment, generating a corresponding serum bilirubin concentration value according to the optical density difference includes:

[0011] According to the optical density difference, the corresponding serum bilirubin concentration value is obtained from a preset optical density difference and serum bilirubin concentration value relationship table.

[0012] In one of the embodiments, the sensor probe is further used to transmit an incident light signal to the skin surface according to a preset emission period within a preset detection period according to the detection signal;

[0013] The control module is also used to calculate an average value of multiple serum bilirubin concentration values ​​within the detection cycle.

[0014] In one embodiment, the sensor probe comprises:

[0015] The inner core is used to receive the short optical path signal reflected by the skin;

[0016] An outer core for receiving the long optical path signal reflected from the skin; and

[0017] An incident light path core disposed between the inner core and the outer core, for emitting an incident light signal toward the skin;

[0018] A first photoelectric converter, connected to the inner core, for converting the short optical path signal into a corresponding short optical path electrical signal;

[0019] A second photoelectric converter is connected to the outer core.

[0020] Used to convert the long optical path signal into a corresponding long optical path electrical signal.

[0021] In one embodiment, the sensor probe further comprises:

[0022] A first scattering plate, disposed between the first photoelectric converter and the inner core, for scattering the short optical path signal;

[0023] The second scattering plate is disposed between the second photoelectric converter and the outer core, and is used for scattering the long optical path signal.

[0024] A second aspect of the embodiments of the present application further provides a jaundice detection device, comprising a jaundice detection circuit as described in any one of the above items.

[0025] In one embodiment, the jaundice detection circuit further comprises:

[0026] The inspection module is used to inspect the sensor probe according to a preset calibration value.

[0027] In one embodiment, the inspection module is a reflective neutral density filter.

[0028] A third aspect of the embodiments of the present application further provides a transcutaneous jaundice tester, comprising a jaundice detection circuit as described in any one of the above items.

[0029] The embodiments of the present application provide a jaundice detection circuit, a jaundice detection device, and a transcutaneous jaundice tester, which receive a detection signal through a sensor probe, emit an incident light signal to the skin surface according to the detection signal, and convert the long light path signal reflected by the skin surface into a long light path electrical signal, and convert the short light path signal reflected by the skin surface into a short light path electrical signal. A control module receives the long light path electrical signal and the short light path signal, obtains an optical density difference according to the long light path electrical signal and the short light path signal, and generates a corresponding serum bilirubin concentration value according to the optical density difference. A display module displays the serum bilirubin concentration value, thereby solving the problems of inaccurate measurement results and poor consistency of test results in current jaundice meters. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 A schematic diagram of the circuit structure of a jaundice detection circuit provided in an embodiment of the present application;

[0031] Figure 2 A schematic diagram of the structure of a sensor probe provided in an embodiment of the present application;

[0032] Figure 3 A schematic diagram of the structure of a photoelectric conversion circuit provided in an embodiment of the present application;

[0033] Figure 4 A schematic diagram of the circuit structure of another jaundice detection circuit provided in an embodiment of the present application;

[0034] Figure 5 A circuit diagram of a detection signal processing module 400 provided in an embodiment of the present application;

[0035] Figure 6 A circuit diagram of a reference voltage circuit of a control module provided in an embodiment of the present application;

[0036] Figure 7 A schematic diagram of the circuit structure of a control module provided in an embodiment of the present application;

[0037] Figure 8 A schematic diagram of the power supply circuit structure of the control module provided in an embodiment of the present application. DETAILED DESCRIPTION

[0038] In order to make the technical problems, technical solutions and beneficial effects to be solved by the present application more clearly understood, the present application is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application and are not used to limit the present application.

[0039] It should be noted that when an element is referred to as being "fixed to" or "disposed on" another element, it can be directly on the other element or indirectly on the other element. When an element is referred to as being "connected to" another element, it can be directly connected to the other element or indirectly connected to the other element.

[0040] It should be understood that the orientation or position relationship indicated by terms such as "length", "width", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside" and "outside" are based on the orientation or position relationship shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present application.

[0041] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of the features. In the description of this application, the meaning of "plurality" is two or more, unless otherwise clearly and specifically defined.

[0042] The present application embodiment provides a jaundice detection circuit, see Figure 1 As shown, the jaundice detection circuit in this embodiment includes: a sensor probe 100, a control module 200, and a display module 300, wherein the sensor probe 100 is used to receive a detection signal, emit an incident light signal to the skin surface according to the detection signal, and convert the long light path signal reflected by the skin surface into a long light path electrical signal, and convert the short light path signal reflected by the skin surface into a short light path electrical signal. The control module 200 is used to receive the long light path electrical signal and the short light path signal, obtain an optical density difference according to the long light path electrical signal and the short light path signal, and generate a corresponding serum bilirubin concentration value according to the optical density difference. The display module 300 is connected to the control module 200 and is used to display the serum bilirubin concentration value.

[0043] In this embodiment, the control module 200 evaluates the yellowness of the skin (composed of the epidermis, dermis and subcutaneous tissue) by measuring the optical density difference between the long optical path electrical signal and the short optical path signal, and obtains the corresponding serum bilirubin concentration value according to a preset relationship table, and the display module 300 displays the serum bilirubin concentration value.

[0044] In a specific application, the sensor probe is measured at the forehead or sternum of the human body, where the blood flow is relatively abundant.

[0045] In one embodiment, the jaundice detection circuit is further provided with a reset module, which can be used to delete the currently displayed measurement value after being powered on, in preparation for the next measurement.

[0046] Furthermore, the jaundice detection circuit is also provided with a switch module for controlling the start-up state of the jaundice detection circuit.

[0047] In one of the embodiments, the switch module and the reset module are powered on simultaneously to control the jaundice detection circuit to enter a calibration mode to perform calibration detection on the sensor probe.

[0048] In one embodiment, the serum bile concentration value is linearly related to the optical density difference.

[0049] In one embodiment, generating a corresponding serum bilirubin concentration value according to the optical density difference includes: obtaining a corresponding serum bilirubin concentration value from a preset optical density difference and serum bilirubin concentration value relationship table according to the optical density difference.

[0050] In one embodiment, the sensor probe 100 is further used to emit an incident light signal to the skin surface according to a preset emission period within a preset detection period based on the detection signal; the control module 200 is further used to calculate an average value of multiple serum bilirubin concentration values ​​within the detection period.

[0051] In one embodiment, see Figure 2 As shown, the sensor probe 100 includes: an inner core 10; an outer core 20; and an incident light path core 30 arranged between the inner core 10 and the outer core 20; a first photoelectric converter 11, connected to the inner core 10, for converting the optical signal output by the inner core 10 into a corresponding electrical signal; a second photoelectric converter 21, connected to the outer core 20, for converting the optical signal output by the outer core 20 into a corresponding electrical signal.

[0052] In one embodiment, see Figure 2As shown, the sensor probe 100 also includes a first scattering plate 12 and a second scattering plate 22. The first scattering plate 12 is arranged between the first photoelectric converter 11 and the inner core 10, and is used for scattering the optical signal output by the inner core 10. The second scattering plate 22 is arranged between the second photoelectric converter 21 and the outer core 20, and is used for scattering the optical signal output by the outer core.

[0053] In this embodiment, one end of the inner core 10 is an incident port for receiving a short optical path signal reflected by the skin, and the other end is connected to the first scattering plate 12; the cross-section of the inner core 10 is circular, and since the plane of the incident port is perpendicular to the plane of the first scattering plate 12, the inner core 10 is set to an "L" shape, and the incident light perpendicular to the plane of the incident port is transmitted to the plane of the first scattering plate 12, and is incident perpendicularly to the plane of the first scattering plate 12; one end of the outer core 20 is an incident port, and the other end is connected to the second scattering plate 22; the cross-section of the outer core 20 is circular, and since the plane of the incident port is perpendicular to the plane of the first scattering plate The planes of the plates 12 are perpendicular to each other, and the outer core 20 is set to an "L" shape, which transmits the incident light from the plane of the perpendicular incident port to the plane of the second scattering plate 22, and is incident on the plane of the second scattering plate 22 perpendicularly; the incident light path core 30 is composed of a cylindrical portion and a rectangular portion, the cross-section of the cylindrical portion is a circular ring, and the cross-section of the rectangular portion is a rectangle, the cylindrical portion and the rectangular portion are perpendicular to each other, the cylindrical portion of the incident light path core 30 is the incident port, and the rectangular portion of the incident light path core 30 is connected to the xenon lamp 00, the incident light path core 30 is sleeved on the outside of the inner core 10, and the outer core 20 is sleeved on the outside of the incident light path core 30.

[0054] In this embodiment, one end of the first scattering plate 12 is connected to the inner core 10, and the other end is provided with a first photoelectric converter 11; one end of the second scattering plate 22 is connected to the outer core 20, and the other end is provided with a second photoelectric converter 21; the first scattering plate 12 and the second scattering plate 22 are arranged on one side of the inner core 10, and the xenon lamp 00 is arranged on the other side of the inner core 10; wherein the first photoelectric converter 11 and the second photoelectric converter 21 can both convert blue light and green light into corresponding electrical signals.

[0055] As an embodiment of the present application, the sensor probe 100 further includes an incident port 40 , which is connected to the incident light path core 30 and is used to receive incident light.

[0056] In this embodiment, the incident light path core 30 is used to transmit the light emitted by the xenon lamp 00 to the incident port. The light irradiates the skin through the incident port. After the light is dispersed in the shallow area of ​​the subcutaneous tissue, a part of the light is reflected to the incident port, and is transmitted through the inner core 10 to the first scattering plate 12. After being scattered by the first scattering plate 12, a first scattered light is formed. The first photoelectric converter 11 collects the first scattered light and generates the light density value of the shallow blue light and the shallow green light of the subcutaneous tissue; after the light is dispersed in the deep area of ​​the subcutaneous tissue, a part of the light is reflected to the incident port, and is transmitted through the outer core 20 to the second scattering plate 22. After being scattered by the second scattering plate 22, a second scattered light is formed; the second photoelectric converter 21 collects the second scattered light and generates the light density value of the deep blue light and the deep green light of the subcutaneous tissue. After processing the light density values ​​of the shallow blue light and the shallow green light and the light density values ​​of the deep blue light and the deep green light, the yellowness of the subcutaneous tissue can be obtained.

[0057] As an embodiment of the present application, the xenon lamp 00 refers to a lamp whose interior is filled with a mixture of inert gases including xenon gas; the xenon lamp 00 uses high voltage current to activate the xenon gas to form strong light; the light emitted by the xenon lamp 00 has strong penetrating power and is suitable for detecting subcutaneous tissue.

[0058] As an embodiment of the present application, the inner core 10 , the outer core 20 , and the incident light path core 30 are all glass fibers.

[0059] In the present embodiment, the main components of the glass fiber are silicon dioxide, aluminum oxide, calcium oxide, boron oxide, magnesium oxide, sodium oxide, etc. The glass fiber has high light conductivity. The inner core 10, outer core 20, and incident light path core 30 made of glass fiber have minimal transmission loss for light reflected from subcutaneous tissue, and can retain the optical density of the light to the greatest extent, thereby improving detection accuracy.

[0060] As an embodiment of the present application, the first photoelectric converter 11 and the second photoelectric converter 21 are both photodiodes; a photodiode is a semiconductor device composed of a PN junction, which can generate current when irradiated by a light beam and has a photoelectric conversion function.

[0061] In this embodiment, the first photoelectric converter 11 and the second photoelectric converter 21 both have the function of collecting blue light and green light. The structure of the first photoelectric converter 11 and the second photoelectric converter 21 of the present application is exactly the same. Taking the first photoelectric converter 11 as an example, the first photoelectric converter 11 includes a first photodiode, a second photodiode, a third photodiode and a fourth photodiode, wherein a green filter is arranged in front of the first photodiode and the second photodiode, which can be used to detect the optical density of green light, and a blue filter is arranged in front of the third photodiode and the fourth photodiode, which can be used to detect the optical density of blue light; the first photoelectric converter 11 adopts different filters and photodiodes to detect green light and blue light at the same time. Since the structure of the second photoelectric converter 21 is exactly the same as that of the first photoelectric converter 11, the first photoelectric converter 11 can also detect green light and blue light at the same time.

[0062] The present application uses filters of different colors to be arranged on the photodiode to achieve the function of collecting light of different colors.

[0063] As an embodiment of the present application, the sensor probe 100 further includes: an encapsulation layer, which is used to encapsulate the inner core 10, the outer core 20 and the incident light path core 30. The material used for the encapsulation layer is plastic, such as resin. Since in this embodiment, the inner core 10, the outer core 20 and the incident light path core 30 are mainly used for light guidance, the surface finish is required to be relatively high, and the use of the encapsulation layer can effectively reduce the damage to the inner core 10, the outer core 20 and the incident light path core 30 caused by external dust, metal chips and other objects.

[0064] As an embodiment of the present application, the inner core 10 , the outer core 20 , and the incident light path core 30 are stacked.

[0065] As an embodiment of the present application, the inner core 10, the outer core 20 and the incident light path core 30 are circular at one end close to the skin.

[0066] In one embodiment, the sensor probe 100 includes: an inner core, an outer core, an incident light path core, an argon lamp, a first photoelectric converter, a second photoelectric converter, a first scattering plate, a second scattering plate, and an incident port;

[0067] In this embodiment, the incident light path core is sleeved on the outside of the inner core, and the outer core is sleeved on the outside of the incident light path core, and the inner core, the outer core and the incident light path core constitute a three-layer light path structure; the three-layer light path structure is close to the skin side as the incident port; the first photoelectric converter is connected to the inner core, and a first scattering plate is arranged between the first photoelectric converter and the inner core; the second photoelectric converter is connected to the outer core, and a second scattering plate is arranged between the second photoelectric converter and the outer core, and the argon lamp is connected to the incident light path core.

[0068] In this embodiment, the argon lamp emits an incident light signal, that is, a light beam with strong penetrating power. The incident light signal is emitted from the incident port through the incident light path core and irradiates the skin tissue. After being dispersed and absorbed in the shallow skin tissue, a short light path signal is generated. The short light path signal enters the inner core from the incident port, is conducted through the inner core, and reaches the first scattering plate. After being diverged by the first scattering plate, it is captured by the first photoelectric converter to obtain a short light path electrical signal. The incident light is dispersed and absorbed in the deep skin tissue to generate a long light path signal. The long light path signal enters the outer core from the incident port, is conducted through the outer core, and reaches the second scattering plate. After being diverged by the second scattering plate, it is captured by the second photoelectric converter to obtain a long light path electrical signal.

[0069] In an application embodiment of the present application, the first photoelectric converter 11 in the sensor probe 100 that captures short optical path signals and converts them into short optical path electrical signals can be a photoelectric converter circuit, and the second photoelectric converter 21 that captures long optical path signals and converts them into long optical path electrical signals can be a photoelectric converter circuit.

[0070] In one embodiment, the photoelectric converter circuit is shown in FIG. Figure 3 The circuit diagram shown.

[0071] See also Figure 3As shown, in this embodiment, the photoelectric conversion circuit includes a first operational amplifier chip U1, a first photodiode PD11, a second photodiode PD12, a third photodiode PD13, a fourth photodiode PD14, a fifth photodiode PD21, a sixth photodiode PD22, a seventh photodiode PD23, an eighth photodiode PD24, a first resistor R1, a second resistor R2, a third resistor R3, a fourth resistor R4, a fifth resistor R5, a sixth resistor R6, a seventh resistor R7, an eighth resistor R8, a first capacitor R1, a second capacitor R2, a third capacitor R3, a fourth capacitor R4, a fifth capacitor R5, a sixth capacitor R6, a seventh capacitor R7, an eighth capacitor R8, a ninth capacitor R9 and a tenth capacitor R10; the first output pin 1OUT of the first operational amplifier chip U1 is the first output end of the photoelectric conversion circuit, the first inverting input pin 1IN- is connected to the first output pin 1OUT through the first resistor R1 and the first capacitor C1, and the first positive input pin 1IN- is connected to the first output pin 1OUT through the first resistor R1 and the first capacitor C1. + is connected to the first differential signal output pin 1IN- through a series circuit of a second resistor R2 and a second capacitor C2, the power pin VDD is connected to the power supply VDD, the power pin VDD is also connected to the first positive phase input pin 1IN+ through a third capacitor C3, the second positive phase input pin 2IN+ is connected to the first positive phase input pin 1IN+, the fourth differential pin 2IN- is connected to the second positive phase input pin 2IN+ through a third resistor R3 and a fourth capacitor C4, the second output pin 2OUT is the second output end of the photoelectric conversion circuit, the second output pin 2OUT is also connected to the second inverting input pin 2IN- through a parallel circuit of a fourth resistor R4 and a fifth capacitor R5, the anode of the first photodiode PD11 and the anode of the third photodiode PD13 are connected to the first inverting input pin 1IN-, the cathode of the first photodiode PD11 and the cathode of the third photodiode PD13 are connected to the first positive phase input pin 1IN+, and serve as the reference voltage signal input pin IN+ of the photoelectric conversion circuit;The second photodiode PD12 and the fourth photodiode PD14 are connected in parallel with the same pole, and the positive end is connected to the second inverting input pin 2IN-, and the negative end is connected to the second positive input pin 2IN+. The third output pin 3OUT is the third output end of the photoelectric conversion circuit. The third inverting input pin 3IN- is connected to the third output pin 3OUT of the first operational amplifier chip U1 through a parallel circuit of a fifth resistor R5 and a sixth capacitor C6. The third positive input pin 3IN+ is connected to the third inverting input pin 3IN- through a series circuit of a sixth resistor R6 and a seventh capacitor C7. The ground pin GND is connected to the ground wire. The fourth positive input pin 4IN+ is grounded through an eighth capacitor C8. The fourth inverting input pin 4 IN- is connected to the fourth positive input pin 4IN+ through the series circuit of the seventh resistor R7 and the ninth capacitor C9, the fourth output pin 4OUT is the fourth output end of the photoelectric conversion circuit, and the fourth output pin 4OUT is also connected to the fourth inverting input pin 4IN- through the parallel circuit of the tenth resistor C10 and the resistor R8, the fifth photodiode PD21 and the seventh photodiode PD23 are connected in parallel with the same pole, and the positive end is connected to the third inverting input pin 3IN-, and the negative end is connected to the third positive input pin 3IN+, the sixth photodiode PD22 and the eighth photodiode PD24 are connected in parallel with the same pole, and the positive end is connected to the fourth inverting input pin 4IN-, and the negative end is connected to the fourth positive input pin 4IN+. ;

[0072] In this embodiment, the first photodiode PD11, the second photodiode PD12, the third photodiode PD13, the fourth photodiode PD14, the fifth photodiode PD21, the sixth photodiode PD22, the seventh photodiode PD23 and the eighth photodiode PD24 together constitute a lighting module of the photoelectric converter circuit.

[0073] In this embodiment, the short optical path electrical signal and the long optical path electrical signal are relatively weak in themselves, and the first operational amplifier chip U1 is used to amplify the collected short optical path electrical signal and the long optical path electrical signal to enhance the signal strength of the short optical path electrical signal and the long optical path electrical signal.

[0074] In this embodiment, when the first photodiode PD11 and the third photodiode PD13 detect blue light, the current of the first photodiode PD11 and the third photodiode PD13 changes, and the corresponding levels of the first inverting input pin 1IN- and the first positive input pin 1IN+ of the first operational amplifier chip U1 change. The first operational amplifier chip U1 obtains a green short optical path signal by detecting the levels of the first inverting input pin 1IN- and the first positive input pin 1IN+ and generates a corresponding green short optical path electrical signal. The green short optical path electrical signal is output through the first output pin OUT1 of the first operational amplifier chip U1.

[0075] When the second photodiode PD12 and the fourth photodiode PD14 detect blue light, the current of the second photodiode PD12 and the fourth photodiode PD14 changes, and the corresponding levels of the second positive input pin 2IN+ and the second inverting input pin 2IN- of the first operational amplifier chip U1 change. The first operational amplifier chip U1 obtains the blue short light path signal by detecting the levels of the second positive input pin 2IN+ and the second inverting input pin 2IN- and generates the corresponding blue short light path electrical signal. The blue short light path electrical signal is output through the second output pin OUT2.

[0076] In this embodiment, since the circuit structures and peripheral circuit structures of the fifth photodiode PD21, the seventh photodiode PD23, the sixth photodiode PD21 and the eighth photodiode PD23 are the same as those of the first photodiode PD11, the third photodiode PD13, the second photodiode PD12 and the fourth photodiode PD14, it can be seen that the first operational amplifier chip U1 obtains a green short optical path signal by detecting the levels of the third inverting input pin 3IN- and the third positive input pin 3IN+ and generates a corresponding green long optical path electrical signal, and the green long optical path electrical signal is output through the third output pin OUT3. The first operational amplifier chip U1 obtains a blue long optical path signal by detecting the levels of the fourth positive input pin 4IN+ and the fourth inverting input pin 4IN- and generates a corresponding blue long optical path electrical signal, and the blue long optical path electrical signal is output through the fourth output pin OUT4.

[0077] The green short optical path electrical signal and the blue short optical path electrical signal together constitute the short optical path electrical signal, and the green long optical path electrical signal and the blue long optical path electrical signal together constitute the long optical path electrical signal.

[0078] In one embodiment, the model of the first operational amplifier chip U1 is TLC274C.

[0079] In one embodiment, the short optical path electrical signal and the long optical path electrical signal are relatively weak. Figure 4 As shown, the jaundice detection circuit in this embodiment also includes a detection signal processing module 400, which is used to amplify the short optical path electrical signal and the long optical path electrical signal to enhance the short optical path electrical signal and the long optical path electrical signal.

[0080] Figure 5 A schematic diagram of the structure of a detection signal processing module 400 provided in one embodiment of the present application.

[0081] See also Figure 5As shown, the first connector CN1 is arranged between the detection signal processing module 400 and the sensor probe 100. Specifically, the first input pin of the first connector CN1 is connected to the first input end 1OUT of the photoelectric conversion circuit, the first output pin of the first connector CN1 is connected to the first input port CN103-1 of the detection signal processing module 400, the first input pin of the first connector CN1 is connected to the first input end 1OUT of the photoelectric conversion circuit, the first output pin of the first connector CN1 is connected to the first input port CN103-1 of the detection signal processing module 400, the first input pin of the first connector CN1 is connected to the first input end 1OUT of the photoelectric conversion circuit, the first output pin of the first connector CN1 is connected to the first input port CN103-1 of the detection signal processing module 400, the second input pin of the first connector CN1 is connected to the power supply VDD, the first output pin of the first connector CN1 is connected to the power supply VCC, and the third input pin of the first connector CN1 is connected to the photoelectric conversion The first input terminal 2OUT of the photoelectric conversion circuit is connected, the third output pin of the first connector CN1 is connected to the second input port CN103-3 of the detection signal processing module 400, the fourth input pin of the first connector CN1 is connected to the third input terminal 3OUT of the photoelectric conversion circuit, the fourth output pin of the first connector CN1 is connected to the third input port CN103-4 of the detection signal processing module 400, the fifth input pin of the first connector CN1 is grounded, the fifth output pin of the first connector CN1 is grounded, the sixth input pin of the first connector CN1 is connected to the fourth input terminal 4OUT of the photoelectric conversion circuit, the sixth output pin of the first connector CN1 is connected to the fourth input port CN103-6 of the detection signal processing module 400, the seventh input pin of the first connector CN1 is connected to the reference voltage input terminal IN+ of the photoelectric conversion circuit, and the seventh output pin Vref of the first connector CN1 is connected to the seventh output pin Vref of the first connector CN1 of the detection signal processing module 400.

[0082] In this embodiment, the detection signal processing module 400 includes: a first four-way analog switch chip M1, a second four-way analog switch chip M2, a second operational amplifier chip N2, a third operational amplifier chip N3, a third four-way analog switch chip M3, a fourth operational amplifier chip N4, a fourth four-way analog switch chip M4, a fifth four-way analog switch chip M5, a sixth four-way analog switch chip M6, a fifth operational amplifier chip N5, a ninth resistor R9, a tenth resistor R10, an eleventh resistor R11, a twelfth resistor R12, a thirteenth resistor R13, a fourteenth resistor R14, a fifteenth resistor R15, a sixteenth resistor R16, and a seventeenth resistor R17, the eighteenth resistor R18, the nineteenth resistor R19, the twentieth resistor R20, the twenty-first resistor R21, the twenty-second resistor R22, the twenty-third resistor R23, the twenty-fourth resistor R24, the twenty-fifth resistor R25, the eleventh capacitor R11, the twelfth capacitor R12, the thirteenth capacitor R13, the fourteenth capacitor R14, the fifteenth capacitor R15, the sixteenth capacitor R16, the seventeenth capacitor R17, the eighteenth capacitor R18, the nineteenth capacitor R19, the twentieth capacitor R20, the twenty-first capacitor R21, the twenty-second capacitor R22, the twenty-third capacitor R23, the twenty-fourth capacitor R24 ​​and the twenty-fifth capacitor R25.

[0083] In the present embodiment, the first input pin 1A of the first four-way analog switch chip M1 is connected to the first input port CN103-1 of the detection signal processing module 400 through the ninth resistor R9, the second input pin 1B of the first four-way analog switch chip M1 is connected to the first input port CN103-1 of the detection signal processing module 400 through the tenth resistor R10, the third input pin 2A of the first four-way analog switch chip M1 is connected to the first input port CN103-1 of the detection signal processing module 400 through the eleventh pin, the fourth input pin 2B of the first four-way analog switch chip M1 is connected to the first input pin 1A, and the fifth input pin 3A of the first four-way analog switch chip M1 is connected to the first input port CN103-1 of the detection signal processing module 400 through the twelfth resistor R12. The second input port CN103-3, the sixth input pin 3B of the first four-way analog switch chip M1 is connected to the second input port CN103-3 of the detection signal processing module 400 through the thirteenth resistor R13, the seventh input pin 4A of the first four-way analog switch chip M1 is connected to the second input port CN103-3 of the detection signal processing module 400 through the fourteenth resistor R14, the eighth input pin 4B of the first four-way analog switch chip M1 is connected to the ninth input pin 3B, the ground pin GND of the first four-way analog switch chip M1 is connected to the ground line, the power pin VCC of the first four-way analog switch chip M1 is connected to the input voltage VCC, and the ground pin GND is connected to the second output pin VCC of the first connector CN1 through the eleventh capacitor C11.

[0084] In this embodiment, the first input pin 1A of the second four-way analog switch chip M2 is connected to the inverting input pin IN1- of the second operational amplifier chip N2, the second input pin 1B is connected to the fourth input pin 2B, the third input pin 2A is connected to the first input pin 1A, the fourth input pin 2B is connected to the output pin of the fifth chip through the fifteenth resistor R15, the fifth input pin 3A is connected to the first input pin 1A, the sixth input pin 3B is connected to the first input pin 1A through the twelfth capacitor C12, and the sixth input pin 3B is also connected to the output pin OUT1 of the second operational amplifier chip N2, the seventh input pin 4A of the second four-way analog switch chip M2 is connected to its sixth input pin 3B, the eighth input pin 4B is connected to the eighth input pin 4B of the sixth chip, the ground pin GND is connected to the ground wire, the power pin VCC is connected to the input voltage VCC, and the ground pin GND is connected to the power pin VCC through the thirteenth capacitor C13; the second output pin 2C is connected to the fourth output pin 4C.

[0085] In this embodiment, the non-inverting input pin IN1 of the second operational amplifier chip N2+the seventh output pin Vtref of the first connector CN1, and the seventh output pin Vtref of the first connector CN1 is used to provide a reference voltage signal.

[0086] In this embodiment, the third operational amplifier chip N3 is an operational amplifier, the inverting input pin IN2- is grounded through the sixteenth resistor R16, the inverting input pin IN2- is also connected to the output pin OUT2, the non-inverting input pin IN2+ is connected to the seventh output pin Vtref of the first connector CN1, and the non-inverting input pin IN2+ is also grounded through the fifteenth capacitor C15; the power pin is connected to the power supply VCC, the power pin is also connected to the seventh output pin Vtref of the first connector CN1 through the fourteenth capacitor C14, and the ground pin is connected to the ground wire.

[0087] In this embodiment, the third operational amplifier chip N3 and its peripheral circuits are used to provide stable reference voltage values ​​to the second four-way analog switch chip M2, the third four-way analog switch chip M3, the fifth four-way analog switch chip M5 and the sixth four-way analog switch chip M6.

[0088] In this embodiment, the first input pin 1A of the third four-way analog switch chip M3 is connected to the inverting input pin IN2- of the fourth operational amplifier chip N4, the second input pin 1B is connected to the sixth input pin 3B of the first four-way analog switch chip M1, the third input pin 2A is connected to the first input pin 1A, the fourth input pin 2B is connected to the fourth input pin 2B of the second four-way analog switch chip M2, the fifth input pin 3A is connected to the first input pin 1A, the sixth input pin 3B is connected to the first input pin 1A through the sixteenth capacitor C16, and the sixth input pin 3B is also connected to the output pin OUT2 of the fourth operational amplifier chip N4, the seventh input pin 4A is connected to the sixth input pin 3B, the eighth input pin 4B is connected to the eighth input pin 4B of the third chip, the ground pin GND is connected to the ground line, the power pin VCC is connected to the input voltage VCC, and the ground pin GND is connected to the power pin VCC through the nineteenth capacitor C19; the second output pin 2C is connected to the fourth output pin 4C, the first output pin 1C, the second output pin 2C, the third output pin 3C, and the fourth output pin 4C are used to output the amplified signal.

[0089] In this embodiment, the fourth operational amplifier chip N4 is an operational amplifier, the positive input pin IN2+ is connected to the seventh output pin Vtref of the first connector CN1, and the positive input pin IN2+ is also grounded through the eighteenth capacitor C18; the power pin is connected to the power supply VCC, and the power pin is also connected to the seventh output pin Vtref of the first connector CN1 through the seventeenth capacitor C17, and the ground pin is connected to the ground wire.

[0090] In this embodiment, the fourth operational amplifier chip N4 and its peripheral circuits are used to provide a stable reference voltage value to the third four-way analog switch chip M3.

[0091] In this embodiment, the first input pin 1A of the fourth four-way analog switch chip M4 is connected to the inverting input pin IN1- of the fifth operational amplifier chip N5, the second input pin 1B is connected to the first input pin 1A of the fifth four-way analog switch chip M5, the third input pin 2A is connected to the first input pin 1A, the fourth input pin 2B is connected to the sixth four-way analog switch chip M6, the fifth input pin 3A is connected to the first input pin 1A, the sixth input pin 3B is connected to the first input pin 1A through the nineteenth capacitor C19, and the sixth input pin 3B is also connected to the fifth The output pin OUT1 of the operational amplifier chip N5, the seventh input pin 4A is connected to the sixth input pin 3B, the eighth input pin 4B is connected to the eighth input pin 4B of the sixth four-way analog switch chip M6, the ground pin GND is connected to the ground line, the power pin VCC is connected to the input voltage VCC, and the ground pin GND is connected to the power pin VCC through the twentieth capacitor C20; the second output pin 2C is connected to the fourth output pin 4C, the first output pin 1C, the second output pin 2C, the third output pin 3C, and the fourth output pin 4C are used to output the amplified signal.

[0092] In this embodiment, the inverting input terminal IN- of the fifth operational amplifier chip N5 is connected to the first input pin 1A of the eighth chip U8, and the non-inverting input terminal IN+ of the fifth operational amplifier chip N5 is connected to the reference voltage Vref.

[0093] In this embodiment, the fifth operational amplifier chip N5 provides a stable reference voltage for the fourth four-way analog switch chip M4.

[0094] In this embodiment, the first input pin 1A of the fifth four-way analog switch chip M5 is connected to the second input pin 1B of the fourth four-way analog switch chip M4, the second input pin 1B is connected to the third input terminal of the control module 200 through the seventeenth resistor R17, the third input pin 2A is connected to the third input terminal of the control module 200 through the eighteenth resistor R18, the fourth input pin 2B is connected to the third input terminal of the control module 200 through the nineteenth resistor R19, the fourth input pin 2B is also connected to the first input pin 1A, and the fifth input pin 3A is connected to the control module 2 through the twentieth resistor R20. 00 fourth input terminal, the sixth input pin 3B is connected to the fourth input terminal of the control module 200 through the twenty-first resistor R21, the seventh input pin 4A is connected to the fourth input terminal of the control module 200 through the twenty-second resistor R22, and the eighth input pin 4B is connected to the sixth input pin 3B; the ground pin GND is connected to the ground wire, the power pin VCC is connected to the input voltage VCC, and the ground pin GND is connected to the power pin VCC through the twenty-first capacitor C21; the first output pin 1C, the second output pin 2C, the third output pin 3C, and the fourth output pin 4C are used to output the amplified signal.

[0095] In this embodiment, the first input pin 1A of the sixth four-way analog switch chip M6 is connected to the inverting input pin IN2- of the sixth operational amplifier chip N6, the second input pin 1B is connected to the sixth input pin 3B of the fifth four-way analog switch chip M5, the third input pin 2A is connected to the first input pin 1A, the fourth input pin 2B is connected to the fourth input pin 2B of the fourth four-way analog switch chip M4, the fifth input pin 3A is connected to the first input pin 1A, the sixth input pin 3B is connected to the first input pin 1A through the twenty-second capacitor C22, and the sixth input pin 3B is also connected to Connected to the output pin OUT2 of the sixth operational amplifier chip N6, the seventh input pin 4A is connected to the sixth input pin 3B, the eighth input pin 4B is connected to the eighth input pin 4B of the fourth four-way analog switch chip M4, the ground pin GND is connected to the ground line, the power pin VCC is connected to the input voltage VCC, and the ground pin GND is connected to the power pin VCC through the twenty-fifth capacitor C25; the second output pin 2C is connected to the fourth output pin 4C, the first output pin 1C, the second output pin 2C, the third output pin 3C, and the fourth output pin 4C are used to output the amplified signal.

[0096] In this embodiment, the sixth operational amplifier chip N6 is an operational amplifier, the positive input pin IN2+ is connected to the seventh output pin Vtref of the first connector CN1, and the positive input pin IN2+ is also grounded through the twenty-fourth capacitor C24; the power pin is connected to the power supply VCC, and the power pin is also connected to the seventh output pin Vtref of the first connector CN1 through the twenty-third capacitor C23, and the ground pin is connected to the ground wire.

[0097] In this embodiment, the sixth operational amplifier chip N6 and its peripheral circuits are used to provide a stable reference voltage value to the sixth four-way analog switch chip M6.

[0098] In this embodiment, the inverting input pin IN1- of the seventh operational amplifier chip N7 is grounded through the twenty-third resistor R23, and the inverting pin is also connected to the eighth pin 4B of the sixth four-way analog switch chip M6. The positive input pin IN1+ is connected to the reference voltage Vref through the twenty-fourth resistor R24, and the positive input pin IN1+ is also grounded through the twenty-fifth pin R25. The output pin OUT1 is used to output the signal.

[0099] In this embodiment, the circuit of the seventh operational amplifier chip N7 is a comparison circuit for outputting the comparison result between the eighth input pin 4B of the fourth four-way analog switch chip M4 and the eighth input pin 4B of the fifth four-way analog switch chip M5 and the reference voltage.

[0100] In this embodiment, the reference voltage is obtained by converting the power supply VCC. Figure 6 A reference voltage circuit is provided for one embodiment, see Figure 6 In this embodiment, the reference voltage circuit includes: a twenty-sixth resistor R26, a twenty-sixth capacitor C26, and a voltage regulator TL1; the cathode K of the voltage regulator TL1 is connected to the power supply VCC through the resistor R26, the anode A is grounded, the reference electrode R is the voltage output end, and the reference voltage Vref is output. The reference electrode R is also connected to the cathode K, and the reference electrode R is also grounded through the twenty-sixth resistor R26.

[0101] In this embodiment, the voltage regulator TL1 is used to convert VCC into a stable reference voltage.

[0102] In one embodiment, when the input power supply VCC increases, the output voltage increases, resulting in an increase in the voltage of the reference electrode R. At this time, the overcurrent generated by the adjustment of the internal circuit of the voltage regulator TL1 increases, which is sufficient to increase the current flowing through the twenty-sixth resistor R26. In this way, the voltage drop of the twenty-sixth resistor R26 increases, and the output voltage is equal to the input power supply VCC minus the voltage drop of the twenty-sixth resistor R26. The input voltage increases and the voltage drop of the current limiting resistor increases, and the output voltage is connected in series to achieve voltage stabilization.

[0103] In one embodiment, the incident light is irradiated on the skin, the light is repeatedly dispersed and absorbed on the skin, and part of the light is reflected back to the sensor probe 100, and is respectively transmitted by the inner core and the outer core to the first photoelectric converter and the second photoelectric converter for collection. The blue wavelength range signal is a blue short optical path signal and a blue long optical path signal, and the green wavelength range signal is a green short optical path signal and a green long optical path signal. The optical density difference can be obtained by comparing the blue wavelength range signal with the green wavelength range signal, and the corresponding serum bilirubin concentration value is obtained from the preset optical density difference and serum bilirubin concentration value relationship table according to the optical density difference.

[0104] In a practical application, the acquired short optical path signal and long optical path signal are detection signals of subcutaneous tissue, and the detection signals of the common part of the epidermis and dermis have been deducted.

[0105] In an actual application, within a preset detection cycle, the control module 200 can control the sensor probe 100 to emit an incident light signal to the skin surface according to a preset emission cycle, and the control module 200 can calculate the average value of multiple serum bilirubin concentration values ​​within the detection cycle.

[0106] In one embodiment, Figure 7 is a schematic diagram of the circuit structure of the control module 200, see Figure 7As shown, in this embodiment, the control module 200 includes a main control chip U14, a twenty-seventh resistor R27, a twenty-eighth resistor R28, a twenty-ninth resistor R29, a thirtieth resistor R30, a thirty-first resistor R31, a twenty-seventh capacitor C27, a twenty-eighth capacitor C28, a twenty-ninth capacitor C29, a thirtieth capacitor C30, a thirty-first capacitor C31, a thirty-second capacitor C32, a thirty-third capacitor C33, a first crystal oscillator XTAL1, a second crystal oscillator XTAL2, a first diode D1 and a first transistor Q1.

[0107] In this embodiment, the signal power pin AVSS of the main control chip U14 is grounded, the first crystal oscillator input pin X1 is connected to the input terminal IN of the first crystal oscillator XTAL1, the first crystal oscillator input pin X1 is also grounded through the twenty-seventh resistor R27, the second crystal oscillator input pin X2 is connected to the output terminal OUT of the first crystal oscillator XTAL1, the second crystal oscillator input pin X2 is also grounded through the twenty-seventh capacitor C27, the first ground pin G1 of the first crystal oscillator XTAL1 is grounded, and the second ground pin G2 of the first crystal oscillator XTAL1 is grounded; the first voltage input pin VSS of the main control chip U14 is grounded, the third crystal oscillator input pin OSC2 is connected to the input pin IN of the second crystal oscillator XTAL2, the fourth crystal oscillator input pin OSC1 is connected to the output pin OUT of the second crystal oscillator XTAL2, and the ground pin GN of the second crystal oscillator XTAL2 is connected to the ground pin G2 of the second crystal oscillator XTAL2. D is grounded; the test pin TEST of the main control chip U14 is grounded, the second voltage input pin CVCC is connected to the +5V power supply, the second voltage input pin CVCC is also grounded through the twenty-eighth capacitor C28, the third voltage input pin VSS is grounded, the fourth voltage input pin V3 is grounded through the twenty-ninth capacitor C29, the fifth voltage input pin V2 is grounded through the thirtieth capacitor C30, the sixth voltage input pin V1 is grounded through the thirty-first capacitor C31, the seventh voltage input pin V0 is connected to the sixth voltage input pin V1 through the twenty-ninth resistor R29, the eighth voltage input pin VCC is connected to the +5V power supply, the input control pin P51 is connected to the collector of the first transistor Q1, the ninth voltage input pin AVCC is connected to the +5V power supply, and the ninth voltage input pin AVCC is also grounded through the thirty-third capacitor C33.

[0108] In this embodiment, the P13 pin and the P15 pin of the main control chip U14 are connected to the IC111_15 of the control module 200, the P30 pin of the main control chip U14 is connected to the IC111_18 of the control module 200, the P32 pin of the main control chip U14 is connected to the IC111_20 of the control module 200, the P36 pin of the main control chip U14 is connected to the IC111_24 of the control module 200, the P52 pin of the main control chip U14 is connected to the IC111_39 of the control module 200, the P53 pin of the main control chip U14 is connected to the IC111_40 of the control module 200, the P54 pin of the main control chip U14 is connected to the IC111_41 of the control module 200, the P55 pin of the main control chip U14 is connected to the IC111_42 of the control module 200, and the P56 pin of the main control chip U14 is connected to the IC111_43 of the control module 200. The P6 pin of the main control chip U14 is connected to IC111_43 of the control module 200, the P30 pin of the main control chip U14 is connected to IC111_18 of the control module 200, the P57 pin of the main control chip U14 is connected to IC111_44 of the control module 200, the P60 pin of the main control chip U14 is connected to IC111_45 of the control module 200, the P61 pin of the main control chip U14 is connected to IC111_46 of the control module 200, the P62 pin of the main control chip U14 is connected to IC111_47 of the control module 200, the P63 pin of the main control chip U14 is connected to IC111_48 of the control module 200, the P64 pin of the main control chip U14 is connected to IC111_49 of the control module 200, and the P65 pin of the main control chip U14 is connected to IC111_50 of the control module 200.

[0109] In this embodiment, the connection relationship between the pins of the control module 200 and the pins of the detection signal processing module 400 is shown in FIG. Figure 5 and Figure 7 shown.

[0110] In this embodiment, the emitter of the first transistor Q1 is grounded, the collector is connected to the input control pin P51 of the main control chip U14, the base is connected to the anode of the first diode D1 through the 30th resistor R30, the cathode of the first diode D1 is connected to the first external input terminal BAT+ of the control module 200, the cathode of the first diode D1 is also connected to the second external input terminal BAT+, the anode of the first diode D1 is also connected to the third external input terminal CHA-, and the anode of the first diode D1 is also connected to the fourth external input terminal CHA+ through a parallel circuit of the 32nd capacitor C32 and the 31st resistor R31.

[0111] In this embodiment, the chip circuit of the control module 200 is mainly used to receive the long optical path electrical signal and the short optical path signal amplified by the detection signal processing module 400, and analyze and process the long optical path electrical signal and the short optical path signal to obtain the detection result; and control the display module 300 to display the detection result.

[0112] In this embodiment, the specific analysis and processing process is to obtain the optical density difference according to the long optical path electrical signal and the short optical path signal, and generate the corresponding serum bilirubin concentration value according to the optical density difference.

[0113] In one embodiment, the model of the main control chip U14 is IC111HD6473827.

[0114] In one embodiment, the circuit for converting the power supply voltage VCC into a +5V voltage is shown in FIG. Figure 8 shown.

[0115] In this embodiment, the drain of the switch tube QD1 is connected to the power supply voltage VCC, the gate is connected to the fourth data exchange pin P32 of the main control chip U14, and the gate is also connected to the source of the switch tube QD1 through the thirty-second resistor R32. The source of the switch tube QD1 is grounded through the resistor C34. One end of the first inductor L1 is connected to the source of the switch tube QD1, and the other end outputs a +5V voltage.

[0116] In this embodiment, the fourth data exchange pin P32 of the main control chip U14 outputs a PWM signal to the gate of the control switch tube QD1, changes the equivalent resistance of the switch tube QD1, and adjusts the voltage value of the output voltage to stabilize the output voltage at +5V.

[0117] In a specific embodiment, the display module 300 displays the yellow degree output by the control module 200, the green short light path signal and the blue short light path signal detected by the first photoelectric converter, the green long light path signal and the blue long light path signal detected by the second photoelectric converter, and the battery power and other information.

[0118] In one embodiment, this embodiment further provides a jaundice detection device, which includes the jaundice detection circuit as described in any one of the above items.

[0119] In one embodiment, the jaundice detection device includes a testing module, and the testing module is used to calibrate the sensor probe 100 according to a preset calibration value.

[0120] Specifically, the sensor probe 100 matches the shape of the verification module.

[0121] In one embodiment, the inspection module is a reflective neutral density filter.

[0122] In this embodiment, after the jaundice detection circuit enters the verification mode, the sensor probe emits incident light, the incident light is emitted to the inspection module, and the corresponding long optical path electrical signal and short optical path signal are generated after reflection. The control module calculates the optical density difference between the long optical path electrical signal and the short optical path signal, and compares the optical density difference with the preset reference density value. If the difference between the optical density difference and the preset reference density value is within the preset range, it is determined that the jaundice detection device is working normally. If the difference between the optical density difference and the preset reference density value exceeds the preset range, it is determined that the jaundice detection device is working abnormally.

[0123] In one embodiment, this embodiment provides a transcutaneous jaundice tester, which includes a jaundice detection circuit as described in any one of the above items.

[0124] The embodiments of the present application provide a jaundice detection circuit, a jaundice detection device, and a transcutaneous jaundice tester, which receive a detection signal through a sensor probe, emit an incident light signal to the skin surface according to the detection signal, and convert the long light path signal reflected by the skin surface into a long light path electrical signal, and convert the short light path signal reflected by the skin surface into a short light path electrical signal. The control module receives the long light path electrical signal and the short light path signal, obtains an optical density difference according to the long light path electrical signal and the short light path signal, and generates a corresponding serum bilirubin concentration value according to the optical density difference. The display module 300 displays the serum bilirubin concentration value, thereby solving the problems of inaccurate measurement results and poor consistency of test results in current jaundice meters.

[0125] The technicians in the relevant field can clearly understand that for the convenience and simplicity of description, only the division of the above-mentioned functional units and modules is used as an example for illustration. In practical applications, the above-mentioned function allocation can be completed by different functional units and modules as needed, that is, the internal structure of the device can be divided into different functional units or modules to complete all or part of the functions described above. The functional units and modules in the embodiment can be integrated in a processing unit, or each unit can exist physically separately, or two or more units can be integrated in one unit. The above-mentioned integrated unit can be implemented in the form of hardware or in the form of software functional units. In addition, the specific names of the functional units and modules are only for the convenience of distinguishing each other, and are not used to limit the scope of protection of this application. The specific working process of the units and modules in the above-mentioned system can refer to the corresponding process in the aforementioned method embodiment, which will not be repeated here.

[0126] In the above embodiments, the description of each embodiment has its own emphasis. For parts that are not described or recorded in detail in a certain embodiment, reference can be made to the relevant descriptions of other embodiments.

[0127] The units described as separate components may or may not be physically separated, and the components shown as units may or may not be physical units, that is, they may be located in one place or distributed on multiple network units. Some or all of the units may be selected according to actual needs to achieve the purpose of the solution of this embodiment.

[0128] In addition, each functional unit in each embodiment of the present application may be integrated into one processing unit, or each unit may exist physically separately, or two or more units may be integrated into one unit. The above-mentioned integrated unit may be implemented in the form of hardware or in the form of software functional units.

[0129] The embodiments described above are only used to illustrate the technical solutions of the present application, rather than to limit them. Although the present application has been described in detail with reference to the aforementioned embodiments, a person skilled in the art should understand that the technical solutions described in the aforementioned embodiments may still be modified, or some of the technical features may be replaced by equivalents. Such modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the embodiments of the present application, and should all be included in the protection scope of the present application.

Claims

1. A jaundice detection circuit, characterized in that: The jaundice detection circuit comprises: A sensor probe, used to receive a detection signal, transmit an incident light signal to a skin surface according to the detection signal, and convert a long light path signal reflected by the skin surface into a long light path electrical signal, and convert a short light path signal reflected by the skin surface into a short light path electrical signal; A control module, configured to receive the long optical path electrical signal and the short optical path signal, obtain an optical density difference according to the long optical path electrical signal and the short optical path signal, and generate a corresponding serum bilirubin concentration value according to the optical density difference; A display module, connected to the control module, for displaying the serum bilirubin concentration value; The sensor probe comprises: The inner core is used to receive the short optical path signal reflected by the skin; An outer core for receiving the long optical path signal reflected from the skin; and An incident light path core disposed between the inner core and the outer core, for emitting an incident light signal toward the skin; A first photoelectric converter, connected to the inner core, for converting the short optical path signal into a corresponding short optical path electrical signal; a second photoelectric converter connected to the outer core and used to convert the long optical path signal into a corresponding long optical path electrical signal; a first scattering plate provided between the first photoelectric converter and the inner core and used to scatter the short optical path signal; A second scattering plate, disposed between the second photoelectric converter and the outer core, for scattering the long optical path signal; The incident light path core is composed of a cylindrical portion and a rectangular portion, the cross-section of the cylindrical portion is a circular ring, the cross-section of the rectangular portion is a rectangle, the cylindrical portion and the rectangular portion are perpendicular to each other, the cylindrical portion of the incident light path core is an incident port, the rectangular portion of the incident light path core is connected to a xenon lamp, the incident light path core is sleeved on the outside of the inner core, and the outer core is sleeved on the outside of the incident light path core.

2. The jaundice detection circuit according to claim 1, characterized in that: The serum bilirubin concentration value is linearly related to the optical density difference.

3. The jaundice detection circuit according to claim 1, characterized in that: Generating a corresponding serum bilirubin concentration value according to the optical density difference comprises: According to the optical density difference, the corresponding serum bilirubin concentration value is obtained from a preset optical density difference and serum bilirubin concentration value relationship table.

4. The jaundice detection circuit according to claim 1, characterized in that: The sensor probe is also used to transmit an incident light signal to the skin surface according to the detection signal within a preset detection period and according to a preset emission period; The control module is also used to calculate an average value of multiple serum bilirubin concentration values ​​within the detection cycle.

5. A jaundice detection device, characterized in that: Comprising the jaundice detection circuit as described in any one of claims 1-4.

6. The jaundice detection device according to claim 5, characterized in that: The jaundice detection circuit also includes: The inspection module is used to inspect the sensor probe according to a preset calibration value.

7. The jaundice detection device according to claim 6, characterized in that: The inspection module is a reflective neutral density filter.

8. A transcutaneous jaundice tester, characterized in that: The jaundice detection circuit comprises the jaundice detection circuit according to any one of claims 1 to 4.

Citation Information

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