A fully automatic specific protein analysis device
By designing a fully automatic specific protein analysis device, using multiple models of attachment fixing mechanisms, stirring mechanisms, laser scattering generation mechanisms and photoelectric signal receiving mechanisms, the existing devices are solved, and the problems of large size, difficult to install, difficult to maintain and high pollution are achieved, and the cost of environmental pollution and pollutant treatment is reduced.
Patent Information
- Application Number
- CN202110223756.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2021-03-01
- Publication Date
- 2025-03-18
- Estimated Expiration
- 2041-03-01
AI Technical Summary
There are many problems with existing specific protein detection devices, including large size, difficulty in cooperating with other equipment, difficulty in maintaining the reaction cup or the use of disposable cups, low signal energy utilization rate, and safety hazards for light leakage, and manual operation, the generation of pollutants caused pressure on the environment, and high cost of treatment of pollutants.
A fully automatic specific protein analysis device is designed, which is connected to multiple in vitro diagnostic medical equipment with liquid circuit functions through multiple models of attachment fixing mechanisms, and the corresponding liquid circuit and inlet and outlet mechanisms are set up, and the reagents are uniformly mixed with the agitator, and the laser scattering generation mechanism and photoelectric signal receiving mechanism are detected to achieve full automation and reduce environmental pollution and pollutant treatment costs.
It realizes the compactness and convenience of the device and the coordinated installation of other equipment, realizes fully automated inspection, reduces environmental pollution and pollutant treatment costs, improves the accuracy of inspection, and ensures the safety of operators.
Smart Images

Figure CN112816724B_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of protein analysis devices, and in particular to a fully automatic specific protein analysis device. Background Art
[0002] C-reaction protein (CRP) is a stress protein in the human body that can react with the formulated reagents to form an immune complex reaction. The concentration of specific proteins contained in the sample can be determined by immunoassay. Currently, most of the devices on the market for detecting specific proteins are based on manually replacing the reaction vessels, with single functions. The reactor and the detection device need to be manually separated and the reactor is a disposable product that needs to be treated at high temperature for harmlessness. The pollutants generated during the treatment process put great pressure on the environment, and the treatment of pollutants greatly increases the cost of detection. In addition, the existing specific protein reaction devices are large in size and difficult to install and use with other equipment. The reaction cup body is difficult to maintain or uses a disposable cup body. The detection element has low signal energy utilization, and light leakage poses a safety hazard. Summary of the invention
[0003] 1. Purpose of the invention
[0004] In order to solve the technical problems existing in the background technology, the present invention proposes a fully automatic specific protein analysis device. The present invention is simple to operate and easy to use. By using a multi-type attachment and fixing mechanism, the device can be assembled into a variety of in vitro diagnostic medical equipment with liquid path functions, and the corresponding liquid path is set to connect with the liquid inlet and outlet mechanism and use the stirring mechanism to stir the reagent. Finally, the hardware and software of the laser scattering generating mechanism and the photoelectric signal receiving mechanism are driven to detect the evenly mixed reagent. No manual operation is required, full automation is realized, and pollution to the environment and the cost of pollutant treatment can be reduced.
[0005] (II) Technical solution
[0006] The present invention provides a fully automatic specific protein analysis device, including a multi-type attachment and fixing mechanism, a stirring mechanism, a liquid inlet and outlet mechanism, a laser scattering generating mechanism and a photoelectric signal receiving mechanism;
[0007] The liquid inlet and outlet mechanism includes multiple groups of cleaning tubes, multiple groups of reagent tubes, a liquid discharge tube and a reaction cup body;
[0008] The reaction cup body is connected to a multi-type attachment and fixing mechanism, and two groups of high-flatness window sheets are arranged on the outer peripheral surface of the reaction cup body; the two groups of high-flatness window sheets are symmetrically distributed with the central axis of the reaction cup body as the center; the upper end surface of the reaction cup body is provided with an opening, the side end surface of the reaction cup body is provided with multiple groups of liquid inlet holes and multiple groups of reagent inlet holes, and the bottom surface of the reaction cup body is provided with a drainage hole;
[0009] The liquid outlets of the multiple groups of cleaning tubes are respectively connected to the multiple groups of liquid inlet holes; the liquid outlets of the multiple groups of reagent tubes are respectively connected to the multiple groups of reagent inlet holes; the liquid inlet of the drain tube is connected to the drain hole;
[0010] The stirring mechanism is connected to the multi-type attachment fixing mechanism, and the stirring end of the stirring mechanism extends from the opening into the reaction cup body to stir the liquid in the reaction cup body;
[0011] The laser scattering generating mechanism comprises a high coaxiality point-shaped laser tube and a laser scattering fixing seat; the laser scattering fixing seat is provided with a receiving groove for matching and receiving a reaction cup body; the bottom surface of the reaction cup body is connected to the bottom surface of the receiving groove; the laser scattering fixing seat is provided with a point-shaped laser emitting hole, a scattered light receiving hole and a light-through hole, and the laser scattering fixing seat is provided with a light-extinguishing baffle; the point-shaped laser emitting hole, the scattered light receiving hole and the light-through hole are all connected with the receiving groove;
[0012] The high coaxiality point-shaped laser tube is connected to the laser scattering fixing seat and is located on a side away from the extinction baffle. The central axis of the laser emitting end of the high coaxiality point-shaped laser tube coincides with the central axis of the point-shaped laser exit hole.
[0013] The photoelectric signal receiving mechanism is connected to the laser scattering fixing seat, the photoelectric signal receiving mechanism and the extinction baffle are located on the same side, and the central axis of the receiving end of the photoelectric signal receiving mechanism coincides with the central axis of the scattered light receiving hole.
[0014] Preferably, the stirring mechanism comprises a motor, a gear transmission group and a stirring paddle;
[0015] One end of the stirring paddle is rotatably connected to the multi-type attachment and fixing mechanism, and the other end of the stirring paddle passes through the opening and extends into the reaction cup body;
[0016] The motor is connected to the multi-model attachment fixing mechanism, and the motor is connected to the stirring paddle through a gear transmission group.
[0017] Preferably, the gear transmission group includes a large gear and a small gear;
[0018] The small gear is connected to the stirring paddle, the center axis of the small gear coincides with the center axis of the stirring paddle, and the small gear is meshed and connected to the large gear; the large gear is connected to the multi-model attachment fixing mechanism through the rotating shaft, and the large gear is connected to the motor through transmission.
[0019] Preferably, the multi-model attachment and fixing mechanism comprises a rotating plate and a fixing seat;
[0020] The cross section of the fixing seat is L-shaped, and a plurality of positioning holes for connecting other devices by bolts are arranged on the vertical end surface of the fixing seat, and a plurality of threaded holes for connecting the motor by bolts are arranged on the horizontal end surface of the fixing seat;
[0021] The rotating plate is connected to the horizontal end surface of the fixed seat, and a space for installing the gear transmission group is reserved between the rotating plate and the horizontal end surface of the fixed seat.
[0022] Preferably, the photoelectric signal receiving mechanism includes an aspherical lens and a circuit board;
[0023] The aspheric lens is assembled on the photocell of the circuit board by molding; the circuit board is provided with a transmitted light through hole, the circuit board is connected to the laser scattering fixing seat, and the circuit board is located on the side away from the high coaxiality point-shaped laser tube.
[0024] Preferably, it further comprises a plurality of first fixing members; wherein the circuit board is provided with a plurality of first mounting holes; and the outer peripheral surface of the laser scattering fixing seat is provided with a plurality of first threaded blind holes;
[0025] The plurality of first fasteners respectively pass through the plurality of first mounting holes and are respectively threaded into the plurality of threaded blind holes.
[0026] Preferably, the angle α between the central axis of the aspheric lens and the central axis of the laser emitting end of the high coaxiality point laser tube is 20° to 30°.
[0027] Preferably, the angle α is 25°.
[0028] Preferably, it also includes multiple groups of second fixing members; wherein, multiple groups of second mounting holes are provided on the multi-model attachment and fixing mechanism; and multiple groups of second threaded blind holes are provided on the reaction cup body;
[0029] The plurality of second fasteners respectively pass through the plurality of second mounting holes and are respectively screwed into the plurality of second threaded blind holes.
[0030] Compared with the prior art, the above technical solution of the present invention has the following beneficial technical effects:
[0031] The fully automatic specific protein analysis device provided by the present invention has a compact structure and is convenient for installation in conjunction with other large-scale equipment, and is thus convenient for assembling the device into a variety of in vitro diagnostic medical equipment with a liquid path function. The corresponding liquid paths are connected to the liquid inlet and outlet mechanisms for use in conjunction with each other, and the reagents can be uniformly mixed and stirred by the provided stirring mechanism. It is best to drive the software and hardware of the high-coaxiality laser tube and the photoelectric signal receiving mechanism to detect the reagents, without manual operation, and can achieve fully automatic detection, and can reduce environmental pollution and the cost of pollutant treatment;
[0032] In the present invention, the solution in the reaction cup body can be effectively and evenly mixed by the stirring mechanism, or the inside of the reaction cup body can be stirred and cleaned by the stirring mechanism to ensure the accuracy of protein detection; the uniformly mixed solution can be detected by the laser scattering generating mechanism and the photoelectric signal receiving mechanism, and the extinction baffle can achieve extinction to avoid light leakage, thereby ensuring the safety of the operator. BRIEF DESCRIPTION OF THE DRAWINGS
[0033] Figure 1 This is a schematic diagram of the three-dimensional structure of a fully automatic specific protein analysis device proposed by the present invention.
[0034] Figure 2 This is an exploded view of a fully automatic specific protein analysis device proposed by the present invention.
[0035] Figure 3 The figure is a three-dimensional structural diagram of a multi-machine type attachment and fixing mechanism in a fully automatic specific protein analysis device proposed by the present invention.
[0036] Figure 4 This is a schematic diagram of the three-dimensional structure of a fixing seat in a fully automatic specific protein analysis device proposed by the present invention.
[0037] Figure 5 The figure is a three-dimensional structural schematic diagram of the liquid inlet and outlet mechanism in a fully automatic specific protein analysis device proposed by the present invention.
[0038] Figure 6 The present invention provides a schematic structural diagram of the liquid inlet and outlet mechanisms in a fully automatic specific protein analysis device.
[0039] Figure 7 This is a schematic diagram of the structure of a fully automatic specific protein analysis device proposed by the present invention.
[0040] Figure 8 This is a schematic diagram of the three-dimensional structure of a photoelectric signal receiving mechanism in a fully automatic specific protein analysis device proposed by the present invention.
[0041] Fig. 9 The figure is a schematic diagram of the structure of a photoelectric signal receiving mechanism in a fully automatic specific protein analysis device proposed by the present invention.
[0042] Figure numerals: 1. Multi-model attachment and fixing mechanism; 101. Rotating plate; 102. Fixing seat; 1021. Second mounting hole; 1022. Threaded hole; 1023. Positioning hole; 2. Stirring mechanism; 201. Motor; 202. Gear transmission group; 203. Stirring paddle; 3. Liquid inlet and outlet mechanism; 301. Cleaning tube; 302. Reagent tube; 303. Drain pipe; 304. High-flatness window piece; 305. Reaction cup body; 306. Opening; 307. Second threaded blind hole; 4. Laser scattering generating mechanism; 401. High-coaxiality point-shaped laser tube; 402. Laser scattering fixing seat; 403. Extinction baffle; 5. Photoelectric signal receiving mechanism; 501. Aspheric lens; 502 Circuit board; 503. First mounting hole; 504. Transmitted light through hole; 6. First fastener. DETAILED DESCRIPTION
[0043] In order to make the purpose, technical scheme and advantages of the present invention clearer, the present invention is further described in detail below in conjunction with specific embodiments and with reference to the accompanying drawings. It should be understood that these descriptions are only exemplary and are not intended to limit the scope of the present invention. In addition, in the following description, the description of well-known structures and technologies is omitted to avoid unnecessary confusion of the concept of the present invention.
[0044] like Figure 1-9 As shown, a fully automatic specific protein analysis device proposed by the present invention includes a multi-type attachment and fixing mechanism 1, a stirring mechanism 2, a liquid inlet and outlet mechanism 3, a laser scattering generating mechanism 4 and a photoelectric signal receiving mechanism 5; wherein the multi-type attachment and fixing mechanism 1 can be connected with a variety of different devices;
[0045] The liquid inlet and outlet mechanism 3 includes multiple groups of cleaning tubes 301, multiple groups of reagent tubes 302, a liquid discharge tube 303 and a reaction cup body 305;
[0046] The reaction cup body 305 is connected to the multi-type attachment and fixing mechanism 1, and two groups of high-flatness window sheets 304 are arranged on the outer peripheral surface of the reaction cup body 305; the two groups of high-flatness window sheets 304 are symmetrically distributed with the central axis of the reaction cup body 305 as the center;
[0047] Furthermore, the cross-sectional shape of each set of high-flatness window sheets 304 is a convex shape; the two sets of high-flatness window sheets 304 are made of highly transparent materials, and the two sets of high-flatness window sheets 304 are attached to the outer peripheral surface of the reaction cup body 305;
[0048] It should be noted that both sides of the reaction cup body 305 are provided with empty grooves and steps for mounting the high-flatness window sheet 304; the steps are coated with a single-component photosensitive adhesive, and the high-flatness window sheet 304 is correspondingly attached, and then light curing is performed to achieve the functions of sealing and light guiding, and light directly irradiates the plane of the high-flatness window sheet 304 without scattering;
[0049] The upper end surface of the reaction cup body 305 is provided with an opening 306, the side end surface of the reaction cup body 305 is provided with multiple groups of liquid inlet holes and multiple groups of reagent inlet holes, and the bottom surface of the reaction cup body 305 is provided with a drainage hole;
[0050] The liquid outlets of the multiple cleaning tubes 301 are respectively connected to the multiple liquid inlet holes; the multiple cleaning tubes 301 are located at the opposite positions of the two sets of high-flatness window sheets 304, which can produce a waterfall-like cleaning effect;
[0051] The liquid outlets of the multiple groups of reagent tubes 302 are respectively connected to the multiple groups of reagent inlet holes;
[0052] The liquid inlet of the drain pipe 303 is connected to the drain hole, and the drain pipe 303 is located on the bottom surface of the reaction cup body 305 to avoid cross contamination with multiple groups of reagent tubes 302;
[0053] The stirring mechanism 2 is connected to the multi-type attachment and fixing mechanism 1, and the stirring end of the stirring mechanism 2 extends into the reaction cup body 305 through the opening 306 to stir the liquid in the reaction cup body 305;
[0054] The laser scattering generating mechanism 4 comprises a high coaxiality point-shaped laser tube 401 and a laser scattering fixing seat 402; the laser scattering fixing seat 402 is provided with a receiving groove for matching and accommodating the reaction cup body 305; the bottom surface of the reaction cup body 305 is connected to the bottom surface of the receiving groove; wherein the reaction cup body 305 is connected to the bottom surface of the receiving groove by bolts;
[0055] The laser scattering fixing seat 402 is provided with a point-shaped laser emission hole, a scattered light receiving hole and a light-through hole, and the laser scattering fixing seat 402 is provided with a light-extinguishing baffle 403; the point-shaped laser emission hole, the scattered light receiving hole and the light-through hole are all connected to the receiving groove;
[0056] Furthermore, the extinction baffle 403 is fixedly connected to the laser scattering fixing seat 402 by screws, so that the extinction baffle 403 can be easily disassembled and assembled. The setting of the extinction baffle 403 can achieve extinction and prevent light leakage, thereby ensuring the safety of the operator.
[0057] The high coaxiality point laser tube 401 is connected to the laser scattering fixing seat 402 and is located on a side away from the extinction baffle 403. The central axis of the laser emitting end of the high coaxiality point laser tube 401 coincides with the central axis of the point laser exit hole.
[0058] The high coaxiality point laser tube 401 is assembled with the laser scattering fixing seat 402 by bolts. When working, the high coaxiality point laser tube 401 can generate a highly collimated laser beam and emit it into the receiving groove through the point laser exit hole, and finally pass through the reaction cup body 305. According to the Lambert-Beer law, scattering and transmission occur at this time. A part of the scattered light enters the scattered light receiving hole with a specific angle α, and the other scattered light is absorbed by the inner wall of the laser scattering fixing seat 402. The light passing through the light hole is absorbed by the extinction baffle 403.
[0059] The photoelectric signal receiving mechanism 5 is connected to the laser scattering fixing seat 402, the photoelectric signal receiving mechanism 5 and the extinction baffle 403 are located on the same side, and the central axis of the receiving end of the photoelectric signal receiving mechanism 5 coincides with the central axis of the scattered light receiving hole.
[0060] In one embodiment of the present invention, a multi-type attachment and fixing mechanism 1 is used to connect with other equipment, so as to facilitate the use of the device with other large medical equipment; the reaction cup body 305 is installed in a fixed manner, and the solution in the reaction cup body 305 can be effectively mixed evenly by the stirring mechanism 2, or the inside of the reaction cup body 305 can be stirred and cleaned by the stirring mechanism 2 to ensure the accuracy of protein detection; the uniformly mixed solution can be detected by the laser scattering generating mechanism 4 and the photoelectric signal receiving mechanism 5, and the extinction baffle 403 can achieve extinction to avoid light leakage, thereby ensuring the safety of the operator.
[0061] In an optional embodiment, the stirring mechanism 2 includes a motor 201, a gear transmission group 202 and a stirring paddle 203;
[0062] One end of the stirring paddle 203 is rotatably connected to the multi-type attachment and fixing mechanism 1, and the other end of the stirring paddle 203 passes through the opening 306 and extends into the reaction cup body 305;
[0063] The motor 201 is connected to the multi-type attachment and fixing mechanism 1, and the motor 201 is connected to the stirring paddle 203 through the gear transmission group 202;
[0064] When in use, the motor 201 drives the gear transmission group 202 to drive the stirring paddle 203 to rotate rapidly to mix the reagents or generate a vortex to clean the interior of the reaction cup body 305 .
[0065] In an optional embodiment, the gear transmission group 202 includes a large gear and a small gear;
[0066] The small gear is connected to the stirring paddle 203, the central axis of the small gear coincides with the central axis of the stirring paddle 203, and the small gear is meshed with the large gear; the large gear is rotatably connected to the multi-type attachment and fixing mechanism 1 through the rotating shaft, and the large gear is transmission-connected to the motor 201;
[0067] When in use, the motor 201 drives the large gear to rotate to drive the small gear to rotate, thereby increasing the rotation speed of the small gear and the stirring paddle 203 to improve the efficiency of reagent mixing or the efficiency of cleaning the inside of the reaction cup body 305.
[0068] In an optional embodiment, the multi-machine attachment and fixing mechanism 1 includes a rotating plate 101 and a fixing seat 102;
[0069] The cross section of the fixing base 102 is L-shaped, and a plurality of positioning holes 1023 for connecting other devices by bolts are provided on the vertical end surface of the fixing base 102, and a plurality of threaded holes 1022 for connecting the motor 201 by bolts are provided on the horizontal end surface of the fixing base 102;
[0070] The rotating plate 101 is connected to the horizontal end surface of the fixing seat 102 , and a space for installing the gear transmission set 202 is reserved between the rotating plate 101 and the horizontal end surface of the fixing seat 102 .
[0071] In an optional embodiment, the photoelectric signal receiving mechanism 5 includes an aspherical lens 501 and a circuit board 502;
[0072] The aspheric lens 501 is assembled on the photocell of the circuit board 502 by molding to achieve the function of focusing the scattered light, thereby increasing the sensitivity of the photoelectric signal; the aspheric lens 501 can improve the sensitivity of the photoelectric reception, and when the device cooperates with the whole machine liquid circuit and hardware to work, when the laser beam passes through the reaction cup body in the working state, the specific protein in the sample and the latex particles in the reagent specifically combine to increase the diameter of the combined particles, and scattering occurs due to the Tyndall effect;
[0073] The circuit board 502 is provided with a transmitted light through hole 504 so that the transmitted light can reach the extinction baffle 403. The circuit board 502 is connected to the laser scattering fixing seat 402. The circuit board 502 is located on a side away from the high coaxiality point-shaped laser tube 401.
[0074] Furthermore, the assembly surface of the circuit board 502 is not provided with any components and is insulated, and the components are all arranged on the back side.
[0075] In an optional embodiment, it further includes a plurality of first fasteners 6; wherein a plurality of first mounting holes 503 are provided on the circuit board 502; and a plurality of first threaded blind holes are provided on the outer peripheral surface of the laser scattering fixing seat 402;
[0076] The plurality of first fasteners 6 respectively pass through the plurality of first mounting holes 503 and are respectively screwed into the plurality of threaded blind holes; the circuit board 502 can be conveniently mounted on the laser scattering fixing seat 402 by means of the plurality of first fasteners 6 .
[0077] In an optional embodiment, the angle α between the central axis of the aspheric lens 501 and the central axis of the laser emitting end of the high-coaxiality point laser tube 401 is 20° to 30°; before use, by setting the angle α, the relationship between the intensity of received scattered light and the particle concentration of the mixed solution is most obvious. The aspheric lens 501 enables the optoelectronic component to receive the scattered light in a specific direction generated during the laser passing through the sample, and outputs a real-time, stable, and highly sensitive optoelectronic signal to the PC end through internal signal processing.
[0078] In an optional embodiment, the angle α is 25°.
[0079] In an optional embodiment, multiple sets of second fasteners are further included; wherein, multiple sets of second mounting holes 1021 are provided on the multi-type attachment and fixing mechanism 1; multiple sets of second threaded blind holes 307 are provided on the reaction cup body 305;
[0080] The plurality of second fasteners respectively pass through the plurality of second mounting holes 1021 and are respectively screwed into the plurality of second threaded blind holes 307 ; the second fasteners are provided to facilitate the detachable mounting of the reaction cup body 305 and the multi-model attachment and fixing mechanism 1 .
[0081] It should be understood that the above specific embodiments of the present invention are only used to illustrate or explain the principles of the present invention, and do not constitute a limitation of the present invention. Therefore, any modifications, equivalent substitutions, improvements, etc. made without departing from the spirit and scope of the present invention should be included in the protection scope of the present invention. In addition, the appended claims of the present invention are intended to cover all changes and modifications that fall within the scope and boundaries of the appended claims, or the equivalent forms of such scope and boundaries.
Claims
1. A fully automatic specific protein analysis device, characterized in that: It comprises a multi-type attachment and fixing mechanism (1), a stirring mechanism (2), a liquid inlet and outlet mechanism (3), a laser scattering generating mechanism (4) and a photoelectric signal receiving mechanism (5); The liquid inlet and outlet mechanism (3) comprises a plurality of cleaning tubes (301), a plurality of reagent tubes (302), a liquid discharge tube (303) and a reaction cup body (305); the reaction cup body (305) is connected to the multi-machine type attachment and fixing mechanism (1); two groups of high-flatness window sheets (304) are provided on the outer peripheral surface of the reaction cup body (305); the two groups of high-flatness window sheets (304) are symmetrically distributed with the central axis of the reaction cup body (305) as the center; an opening (306) is provided on the upper end surface of the reaction cup body (305); a plurality of groups of liquid inlet holes and a plurality of groups of reagent inlet holes are provided on the side end surface of the reaction cup body (305); a liquid discharge hole is provided on the bottom surface of the reaction cup body (305); the liquid discharge tube openings of the plurality of cleaning tubes (301) are respectively connected to the plurality of liquid inlet holes; the liquid discharge tube openings of the plurality of reagent tubes (302) are respectively connected to the plurality of reagent inlet holes; and the liquid inlet tube opening of the liquid discharge tube (303) is connected to the liquid discharge hole; The stirring mechanism (2) is connected to the multi-type attachment and fixing mechanism (1), and a stirring end of the stirring mechanism (2) extends from the opening (306) into the reaction cup body (305) to stir the liquid in the reaction cup body (305); The laser scattering generating mechanism (4) comprises a high-coaxiality point-shaped laser tube (401) and a laser scattering fixing seat (402); the laser scattering fixing seat (402) is provided with a receiving groove for cooperating with and receiving a reaction cup body (305); the bottom surface of the reaction cup body (305) is connected to the bottom surface of the receiving groove; the laser scattering fixing seat (402) is provided with a point-shaped laser emission hole, a scattered light receiving hole and a light-through hole, and the laser scattering fixing seat (402) is provided with an extinction baffle (403); the point-shaped laser emission hole, the scattered light receiving hole and the light-through hole are all connected to the receiving groove; the high-coaxiality point-shaped laser tube (401) is connected to the laser scattering fixing seat (402) and is located on a side away from the extinction baffle (403), and the central axis of the laser emitting end of the high-coaxiality point-shaped laser tube (401) coincides with the central axis of the point-shaped laser emission hole; The photoelectric signal receiving mechanism (5) is connected to the laser scattering fixing seat (402), the photoelectric signal receiving mechanism (5) and the light extinction baffle (403) are located on the same side, and the central axis of the receiving end of the photoelectric signal receiving mechanism (5) coincides with the central axis of the scattered light receiving hole; the photoelectric signal receiving mechanism (5) comprises an aspherical lens (501) and a circuit board (502); The aspheric lens (501) is assembled on the photocell of the circuit board (502) by molding; the circuit board (502) is provided with a transmitted light through hole (504); the circuit board (502) is connected to the laser scattering fixing seat (402); and the circuit board (502) is located on a side away from the high coaxiality point-shaped laser tube (401); The angle α between the central axis of the aspheric lens (501) and the central axis of the laser emission end of the high coaxiality point-shaped laser tube (401) is 20° to 30°; It also includes a plurality of groups of first fastening members (6); wherein the circuit board (502) is provided with a plurality of groups of first mounting holes (503); and a plurality of groups of first threaded blind holes are provided on the outer peripheral surface of the laser scattering fixing seat (402); The plurality of first fastening members (6) respectively pass through the plurality of first mounting holes (503) and are respectively threadedly screwed into the plurality of threaded blind holes.
2. A fully automatic specific protein analysis device according to claim 1, characterized in that: The stirring mechanism (2) comprises a motor (201), a gear transmission group (202) and a stirring paddle (203); One end of the stirring paddle (203) is rotatably connected to the multi-type attachment and fixing mechanism (1), and the other end of the stirring paddle (203) passes through the opening (306) and extends into the reaction cup body (305); The motor (201) is connected to the multi-type attachment fixing mechanism (1), and the motor (201) is connected to the stirring paddle (203) through a gear transmission group (202).
3. A fully automatic specific protein analysis device according to claim 2, characterized in that: The gear transmission group (202) includes a large gear and a small gear; The small gear is connected to the stirring paddle (203), the central axis of the small gear coincides with the central axis of the stirring paddle (203), and the small gear is meshedly connected to the large gear; the large gear is rotatably connected to the multi-model attachment fixing mechanism (1) via a rotating shaft, and the large gear is transmission-connected to the motor (201).
4. A fully automatic specific protein analysis device according to claim 3, characterized in that: The multi-machine type attachment and fixing mechanism (1) comprises a rotating plate (101) and a fixing seat (102); The cross section of the fixing seat (102) is L-shaped, a plurality of groups of positioning holes (1023) for connecting to other devices by means of bolts are provided on the vertical end surface of the fixing seat (102), and a plurality of groups of threaded holes (1022) for connecting to the motor (201) by means of bolts are provided on the horizontal end surface of the fixing seat (102); The rotating plate (101) is connected to the horizontal end surface of the fixed seat (102), and a space for installing the gear transmission group (202) is reserved between the rotating plate (101) and the horizontal end surface of the fixed seat (102).
5. A fully automatic specific protein analysis device according to claim 1, characterized in that: The angle α is 25°.
6. A fully automatic specific protein analysis device according to claim 1, characterized in that: It also includes multiple groups of second fixing members; wherein the multi-type attachment and fixing mechanism (1) is provided with multiple groups of second mounting holes (1021); and the reaction cup body (305) is provided with multiple groups of second threaded blind holes (307); The plurality of sets of second fasteners respectively pass through the plurality of sets of second mounting holes (1021) and are respectively threadedly screwed into the plurality of sets of second threaded blind holes (307).
Citation Information
Patent Citations
Full-automatic specific protein analysis device
CN214473433U