Keratin membrane patch pretreatment components

Abstract

The present invention relates to the technical field of automated equipment, and discloses a keratin membrane patch pretreatment component, comprising a clamp unit, a pressing unit, a stage unit and a folding unit, wherein the clamp unit removes and clamps the patch from the membrane, sends it to the drug-carrying skin of the stage unit, and after being pressed at a fixed time and pressure by the pressing unit, sends it to the folding unit for folding, and the clamp unit sends the folded patch to a centrifuge tube. The present invention realizes automated pretreatment of multiple keratin membrane patches at the same time, and realizes the entire pretreatment process from film peeling, pasting, and curling.

Description

Technical Field

[0001] The invention relates to the technical field of automated equipment, and in particular to a keratin membrane patch pretreatment component. Background Art

[0002] For the keratin extraction and testing process of animal skin, the existing operating procedure is to remove the patch on the rectangular film material, stick it on the drug-loaded animal skin to absorb the stratum corneum on it, and after the absorption is completed, the patch is curled and sent to a centrifuge bottle to complete the pre-treatment.

[0003] The manual operation process is not only cumbersome but also has a lot of uncertainties. Operators use manual tools to remove the patches one by one, which is inefficient and has poor consistency in operation, ultimately leading to large errors in the test results. Summary of the invention

[0004] The purpose of the present invention is to solve the above problems and provide a keratin membrane patch pretreatment component to achieve automated pretreatment of multiple keratin membrane patches at the same time, and realize the entire pretreatment process from peeling, pasting, and curling.

[0005] The technical solution adopted by the present invention is:

[0006] A keratin membrane patch pretreatment component is characterized in that it includes a clamp unit, a pressing unit, a carrier unit and a folding unit. The clamp unit removes the patch from the membrane and clamps it, and sends it to the drug-carrying skin of the carrier unit. After being pressed at a fixed time and pressure by the pressing unit, it is sent to the folding unit for folding. The clamp unit sends the folded patch to a centrifuge tube.

[0007] Furthermore, the clamp unit includes a row of clamping jaws formed by the cooperation of an upper clamping plate and a lower clamping plate, a number of clamping jaws on the clamping jaw row are arranged side by side, the upper clamping plate is fixed, the lower clamping plate is connected to the rotating shaft through a pressure spring, the upper clamping plate and the lower clamping plate are normally open, a pressing plate is arranged behind the rotating shaft of the lower clamping plate, and a vertical cylinder is fixed above the pressing plate. When the vertical cylinder presses the pressing plate, the lower clamping plate flips upward and cooperates with the upper clamping plate to make the clamping jaws in a clamping state.

[0008] Furthermore, the extending arm of the clamping jaw forms a bending portion downward, the end of the extending arm is a clamping head, and a rubber block is arranged inside the clamping head.

[0009] Furthermore, the pressing unit is multiple, including a driving shaft, a sleeve and a pressing head. A spring is arranged in the sleeve. When the driving shaft descends, the spring generates a fixed pressure on the pressing head.

[0010] Furthermore, the platform unit includes a frame and an array slot arranged on the frame, the slot hole of each slot is used to place the drug-carrying skin, and the number of columns of the array slot matches the number of clamps.

[0011] Furthermore, a side hole is provided at the front end of each slot hole, and the side hole is used to cooperate with the bending portion of the clamping claw.

[0012] Furthermore, the folding unit includes a plurality of air grippers arranged side by side, the number of the air grippers matches the number of the clamping jaws, the opening of the air grippers is greater than the width of the patch, and a bell mouth is arranged below the air grippers.

[0013] Furthermore, slide rails are arranged on both sides of the platform frame of the platform unit, and the folding unit is arranged on the slide rails.

[0014] Furthermore, the driving cylinders of the air gripper are arranged crosswise in the horizontal and vertical directions.

[0015] Furthermore, the clamp unit and the pressing unit are two sets, which pre-process the patch alternately, and the carrier unit moves on the slide rail to cooperate with the two sets of clamp units and the pressing unit to perform the bending operation.

[0016] The beneficial effects of the present invention are:

[0017] (1) Implement preprocessing operations on multiple patches;

[0018] (2) Dual-thread operation to improve preprocessing efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Attached Figure 1 It is a three-dimensional structural schematic diagram of the present invention;

[0020] Attached Figure 2 It is a three-dimensional structural schematic diagram of the clamp unit and the pressing unit;

[0021] Attached Figure 3 is a schematic diagram of the three-dimensional structure of the fixture unit;

[0022] Attached Figure 4 It is a three-dimensional structural schematic diagram of the stage unit and the folding unit;

[0023] Attached Figure 5 It is a partial enlarged view of the folding unit without the outer shell;

[0024] Attached Figure 6 It is a schematic diagram of the structure of the patch after being folded.

[0025] The reference numerals in the accompanying drawings are:

[0026] 1. Patch; 2. Fixture unit;

[0027] 3. Pressing unit; 4. Carrier unit;

[0028] 5. Folding and pressing unit; 6. Upper clamping plate;

[0029] 7. Lower clamping plate; 8. Clamping claw;

[0030] 9. Bending part; 10. Chuck;

[0031] 11. Rubber block; 12. Transverse cylinder;

[0032] 13. Drive shaft; 14. Sleeve;

[0033] 15. Press head; 16. Stand;

[0034] 17. Array slot; 18. Slot hole;

[0035] 19. Side hole; 20. Air gripper;

[0036] 21. Bell mouth; 22. Slide rail;

[0037] 23. Driving cylinder; 24. Vertical cylinder;

[0038] 25. Press the board. DETAILED DESCRIPTION

[0039] The specific implementation of the keratin membrane patch pretreatment component of the present invention will be described in detail below with reference to the accompanying drawings.

[0040] See attached Figure 1 The pretreatment process of the keratin membrane patch 1 mainly includes sending the patch 1 to the carrier of the drug-loaded skin for pressing and extraction, and then sending it to the centrifuge tube after bending or pressing the crease. The whole process is completed by the clamp unit 2, the pressing unit 3, the carrier unit 4 and the folding unit 5. The clamp unit 2 removes the patch 1 from the membrane and clamps it, and sends it to the drug-loaded skin of the carrier unit 4. After being pressed at a fixed time and pressure by the pressing unit 3, it is sent to the folding unit 5 for folding. The clamp unit 2 sends the folded patch 1 to the centrifuge tube.

[0041] See attached Figure 2 ,The clamping unit 2 and the pressing unit 3 are arranged on the same robotic arm and the two work in coordination.

[0042] See attached Figure 3 The clamp unit 2 clamps the patch 1 to ensure the clamping reliability in the whole process. The clamp unit 2 includes a clamping claw row formed by the cooperation of the upper clamp plate 6 and the lower clamp plate 7. A plurality of clamping claws 8 are arranged side by side on the clamping claw row. The upper clamp plate 6 is fixed, and the lower clamp plate 7 is connected to the rotating shaft through a pressure spring. The upper clamp plate 6 and the lower clamp plate 7 are normally open. A pressing plate 25 is arranged behind the rotating shaft of the lower clamp plate 7. A vertical cylinder 24 is fixed above the pressing plate 25. When the vertical cylinder 24 presses the pressing plate 25, the lower clamp plate 7 flips upward to cooperate with the upper clamp plate 6, so that the clamping claws 8 are in a clamping state.

[0043] The extended arm of the clamp 8 forms a bent portion 9 downward, and the end of the extended arm is a clamp 10, and a rubber block 11 is arranged in the clamp 10. The structure of the bent portion 9 facilitates the clamp 8 to clamp the patch 1 and place the patch 1 on the stage unit 4, reducing interference in mechanical design. The entire clamp unit 2 is driven by a horizontal cylinder 12 to achieve horizontal movement.

[0044] See attached Figure 2 There are multiple pressing units 3, including a driving shaft 13, a sleeve 14 and a pressing head 15. A spring is arranged in the sleeve 14. When the driving shaft 13 descends, the spring generates a fixed pressure on the pressing head 15. The pressing unit 3 has the same number of jaws 8 as the jaw 8 unit, and the position of each pressing head 15 corresponds to the position of the patch 1 clamped by the jaw 8. The pressure of the spring is set to 1N as needed.

[0045] See attached Figure 4 The stage unit 4 includes a stage 16 and an array slot 17 arranged on the stage 16. The slot holes 18 of each slot are used to place the drug-carrying skin. The number of rows of the array slots 17 matches the number of the clamping jaws 8. A side hole 19 is arranged at the front end of each slot hole 18. The side hole 19 is used to match the bending part 9 of the clamping jaw 8.

[0046] See attached Figure 5 The folding and pressing unit 5 includes a plurality of air grippers 20 arranged side by side, the number of the air grippers 20 matches the number of the clamping jaws 8, the opening of the air grippers 20 is greater than the width of the patch 1, and a bell mouth 21 is arranged below the air grippers 20. Slide rails 22 are arranged on both sides of the platform 16 of the stage unit 4, and the folding and pressing unit 5 is arranged on the slide rails 22. The driving cylinders 23 of the air grippers 20 are arranged crosswise in the horizontal direction and the vertical direction.

[0047] The working process of the present invention is described below. The clamp unit 2 grabs five patches 1 at a time through the clamping claw row, and adjusts the position through the transverse cylinder 12 so that the five patches 1 are located directly below the pressure heads 15 of the five pressing units 3. The clamp unit 2 and the pressing unit 3 are moved by the mechanical arm and sent to the top of the stage unit 4. The clamp unit 2 and the pressing unit 3 are lowered, and the clamp 8 is lowered to the array slot 17 of the stage unit 4. The clamp head 10 of the clamp 8 falls into the side hole 19, so that the patch 1 is just in contact with the drug-carrying skin in the array slot 17, and then the pressure head of the pressing unit 3 is driven. 15 is pressed down onto patch 1, and the pressure is preset to 1N for 5 seconds. After completion, the patch 1 is pushed forward to the folding unit 5 behind the stage unit 4, and the patch 1 is fed upward from the bottom of the bell mouth 21 below the air gripper 20 of the folding unit 5. Due to the squeezing effect of the bell mouth 21, the patch 1 is elastically deformed after being pressed and bent downward. When the air gripper 20 of the folding unit 5 is clamped, the patch 1 is folded in half. Depending on the composition and thickness of the adhesive surface on the patch 1, folding and pressing may produce creases and the patch 1 may not stick together, or the patch 1 may stick together (see attached Figure 6), no matter which case, the predetermined effect is achieved. Finally, the folded patch 1 can be directly placed in the centrifuge tube by the clamping jaws 8, and the patch 1 with creases can be placed in the centrifuge tube after being folded along the creases due to the elasticity of the patch 1 when inserted into the centrifuge tube.

[0048] See attached Figure 1 There are two sets of clamp units 2 and pressing units 3, which pre-treat the patch 1 alternately, and the stage unit 4 moves on the slide rail 22 to cooperate with the two sets of clamp units 2 and pressing units 3 to perform bending operations. With the arrangement of the multi-array drug-carrying skin of the stage, continuous pre-treatment operations of more than 30 patches 1 can be achieved.

[0049] The above is only a preferred embodiment of the present invention. It should be pointed out that ordinary technicians in this technical field can make several improvements and modifications without departing from the principle of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. A keratin membrane patch pretreatment component, characterized in that: It includes a clamp unit, a pressing unit, a platform unit and a folding unit. The clamp unit removes the patch from the diaphragm and clamps it, and sends it to the drug-loaded skin of the platform unit. After being pressed at a fixed time and pressure by the pressing unit, it is sent to the folding unit for folding. The clamp unit sends the folded patch to the centrifuge tube. The clamp unit includes a row of clamping jaws formed by the cooperation of an upper clamping plate and a lower clamping plate. A number of clamping jaws on the clamping jaw row are arranged side by side. The upper clamping plate is fixed, and the lower clamping plate is connected to the rotating shaft through a pressure spring. The upper clamping plate and the lower clamping plate are normally open. A pressing plate is arranged behind the rotating shaft of the lower clamping plate, and a vertical cylinder is fixed above the pressing plate. When the vertical cylinder presses the pressing plate, the lower clamping plate flips upward and cooperates with the upper clamping plate to make the clamping jaws in a clamping state. There are multiple pressing units, including a driving shaft, a sleeve and a pressure head. A spring is arranged in the sleeve. When the driving shaft descends, the spring generates a fixed pressure on the pressure head.

2. The keratin membrane patch pretreatment component according to claim 1, characterized in that: The extending arm of the clamping claw forms a bending portion downward, and the end of the extending arm is a clamping head, in which a rubber block is arranged.

3. The keratin membrane patch pretreatment component according to claim 2, characterized in that: The platform unit comprises a platform and an array slot arranged on the platform, the slot hole of each slot is used to place the drug-carrying skin, and the number of rows of the array slot matches the number of the clamping jaws.

4. The keratin membrane patch pretreatment component according to claim 3, characterized in that: A side hole is provided at the front end of each slot hole, and the side hole is used to cooperate with the bending portion of the clamping claw.

5. The keratin membrane patch pretreatment component according to claim 3, characterized in that: The folding unit includes a plurality of air grippers arranged side by side, the number of the air grippers matches the number of the clamping jaws, the opening of the air grippers is greater than the width of the patch, and a bell mouth is arranged below the air grippers.

6. The keratin membrane patch pretreatment component according to claim 5, characterized in that: Slide rails are arranged on both sides of the platform frame of the platform unit, and the folding unit is arranged on the slide rails.

7. The keratin membrane patch pretreatment component according to claim 5, characterized in that: The driving cylinders of the air gripper are arranged crosswise in horizontal and vertical directions.

8. The keratin membrane patch pretreatment component according to claim 5, characterized in that: The clamp unit and the pressing unit are two sets, which pre-process the patch alternately, and the carrier unit moves on the slide rail to cooperate with the two sets of clamp units and the pressing unit to perform the bending operation.

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