Cold cycle radio frequency needle temperature calibration device and calibration method

Abstract

The present invention discloses a temperature calibration device and calibration method for a cold-circulation radio frequency needle. The temperature calibration device includes a constant-temperature water tank, an interface module, a water chiller, a controller, a computer and an interactive module. The radio frequency needle holder is arranged in the constant-temperature water tank. The controller is electrically connected to the computer and the interface module respectively, and the interactive module is connected to the computer. When performing temperature calibration, the signal connection end of the cold-circulation radio frequency needle is connected to the radio frequency needle interface of the interface module, the cooling interface is connected to the circulating water interface of the water chiller, and one end of the cold-circulation radio frequency needle is inserted into the liquid of the constant-temperature water tank. The calibration method adopts the temperature calibration device to obtain the temperature calibration function corresponding to the cold-circulation radio frequency needle in two working modes, which is suitable for the temperature detection of the cold-circulation radio frequency needle in the two working modes during treatment, and improves the accuracy of temperature control during treatment.

Description

Technical Field

[0001] The invention relates to the field of temperature calibration, and in particular to a cold cycle radio frequency needle temperature calibration device and a calibration method. Background Art

[0002] Cold cycle radiofrequency ablation (RFA) is a new minimally invasive technology used to treat solid tumors in recent years. RFA uses a cold cycle radiofrequency needle to connect to a treatment device with a cold cycle system through a connecting line. With the guidance of imaging technology (ultrasound or CT, MR), the needle electrode is directly placed into the tumor tissue cells. The radio frequency RF (Radio frequency) energy changes the current intensity flowing through the tissue to generate molecular friction, increase the temperature in the cells (70℃-90℃), and make the local tumor tissue produce high temperature and dehydration, so as to achieve the effect of rapid protein denaturation and coagulation inactivation of tumor cells to treat tumors. At the same time, the needle electrode is directly cooled by cooling water, which overcomes the long-standing problem of carbon coagulation in radio frequency thermal therapy and effectively expands the ablation range of the product.

[0003] At present, the cold circulation radio frequency needle uses a thermocouple as a temperature sensor for temperature detection, and the thermocouple is set near the tip of the cold circulation radio frequency needle. When the cold circulation radio frequency needle is working with cold circulation water, the temperature detected at the temperature sensing point of the cold circulation radio frequency needle tip is the combined effect temperature of the temperature around the cold circulation radio frequency needle tip and the temperature of the cold circulation water. Due to the influence of the cold circulation water on temperature detection, the detection temperature is quite different when the cold circulation water is passed and when it is not passed. The difference can generally reach 10-20℃, which affects the accurate control of the radio frequency ablation temperature during the treatment process. Summary of the invention

[0004] The first object of the present invention is to provide a cold cycle radio frequency needle temperature calibration device, which can calibrate the temperature detection of the cold cycle radio frequency needle. The first object of the present invention is achieved by the following technical solutions:

[0005] A cold-circulation radio frequency needle temperature calibration device, characterized in that it includes a constant-temperature water tank, an interface module, a chiller, a controller, a computer and an interactive module, wherein the radio frequency needle holder is arranged in the constant-temperature water tank, the controller is electrically connected to the computer and the interface module respectively, and the interactive module is connected to the computer; when performing temperature calibration, the signal connection end of the cold-circulation radio frequency needle is connected to the radio frequency needle interface of the interface module, the cooling interface is connected to the circulating water interface of the chiller, and one end of the cold-circulation radio frequency needle is inserted into the liquid in the constant-temperature water tank.

[0006] In the above technical scheme, a constant temperature water tank is set up, and the cold circulation radio frequency needle is inserted into the constant temperature water tank. The temperature value detected by the cold circulation radio frequency needle is compared with the liquid temperature value of the constant temperature water tank, and the temperature calibration function of the cold circulation radio frequency needle in the two working modes of not passing cold circulation water and passing cold circulation water is calculated respectively, so as to accurately control the temperature during the treatment process and improve the treatment effect.

[0007] As a further improvement of the present invention, it also includes a radio frequency needle rack, on which at least one radio frequency needle placement position is provided, and when performing temperature calibration, the cold cycle radio frequency needle is placed in the radio frequency needle placement position.

[0008] As a further improvement of the present invention, the RF pin interface of the interface module and the circulating water interface of the chiller are both multiple and are used to simultaneously connect multiple cold circulation RF pins.

[0009] As a further improvement of the present invention, a relay is provided on the interface module for selecting / deselecting the cold cycle radio frequency needle to be calibrated.

[0010] As a further improvement of the present invention, the controlled end of the chiller is electrically connected to an external power supply or the controller / interface module / computer, and the controller controls the start and stop or working efficiency of the chiller.

[0011] As a further improvement of the present invention, the constant temperature water tank is electrically connected to an external power supply or the controller / interface module / computer, and the controller controls the start and stop or temperature of the constant temperature water tank.

[0012] The cold circulation radio frequency needle temperature calibration device is capable of realizing simultaneous calibration of multiple cold circulation radio frequency needles and improving calibration efficiency by setting a constant temperature water tank, setting a radio frequency needle rack in the constant temperature water tank, and setting an interface module with multiple radio frequency needle interfaces, a chiller with multiple circulating water interfaces, and a relay.

[0013] The second object of the present invention is to provide a cold cycle radio frequency needle temperature calibration method, which can calculate the temperature calibration function of the cold cycle radio frequency needle. The second object of the present invention is achieved by the following technical solutions:

[0014] The cold cycle radio frequency needle temperature calibration method is characterized by: using the cold cycle radio frequency needle temperature calibration device described above, including the following steps:

[0015] (1) Connect the signal connection end of the cold circulation RF needle to the RF needle interface of the interface module, and connect the cooling interface to the circulating water interface of the chiller;

[0016] (2) placing the cold circulation radio frequency needle on the radio frequency needle holder, and inserting one end of the cold circulation radio frequency needle into the liquid in the constant temperature water tank;

[0017] (3) starting the cold cycle radio frequency needle temperature calibration device;

[0018] (4) starting the chiller;

[0019] (5) Perform cold cycle RF needle temperature calibration.

[0020] In the above technical scheme, by inserting the cold circulation radio frequency needle into a constant temperature water tank, the temperature value detected by the cold circulation radio frequency needle is compared with the liquid temperature value of the constant temperature water tank, and the temperature calibration function of the cold circulation radio frequency needle in two working modes, namely, without the introduction of cold circulation water and with the introduction of cold circulation water, is calculated respectively. The temperature calibration function is applied to the treatment process of the cold circulation radio frequency needle, thereby improving the accuracy of temperature control during the treatment process.

[0021] As a further improvement of the present invention, the step (5) comprises the following steps:

[0022] (5a) setting the temperature of the constant temperature water tank to T1, and waiting for the liquid temperature in the water tank to reach a preset temperature;

[0023] (5b) the computer sends a test command to the controller not to pass cold circulating water;

[0024] (5c) Wait and determine whether the controller returns the correct test data TS1; if so, proceed to the next step; if not, continue waiting;

[0025] (5d) setting the temperature of the constant temperature water tank to T2, and waiting for the temperature of the liquid in the water tank to reach a preset temperature;

[0026] (5e) the computer sends a cold circulating water test command to the controller;

[0027] (5f) Wait and determine whether the controller returns the correct test data TS2; if so, proceed to the next step; if not, continue waiting;

[0028] (5g) setting the temperature of the constant temperature water tank to T3, and waiting for the temperature of the liquid in the water tank to reach a preset temperature;

[0029] (5h) Repeat steps (5b) and (5c) to obtain test data TS3 according to T3;

[0030] (5i) setting the temperature of the constant temperature water tank to T4, and waiting for the liquid temperature in the water tank to reach a preset temperature;

[0031] (5j) Repeat steps (5e) and (5f) to obtain test data TS4 according to T4;

[0032] (5k) Substitute T1, TS1, T3, and TS3 into the original temperature calibration function to obtain the temperature calibration function parameters K1 and B1 when no cold circulating water is introduced; substitute T2, TS2, T4, and TS4 into the original temperature calibration function to obtain the temperature calibration function parameters K2 and B2 when cold circulating water is introduced;

[0033] (51) Based on the calculated K1, B1, K2, and B2, when using the cold circulation radio frequency needle, the temperature calibration function parameters applicable to the needle are selected according to whether cold circulation water is passed through the needle.

[0034] As a further improvement of the present invention, T1≠T3 and T2≠T4.

[0035] As a further improvement of the present invention, the original temperature calibration function is T=K*TS+B.

[0036] In the cold circulation radio frequency needle temperature calibration method, the cold circulation radio frequency needle is tested in two working modes, namely, without cold circulation water and with cold circulation water, and the temperature calibration function corresponding to the cold circulation radio frequency needle in the two working modes is calculated and applied to the treatment process of the cold circulation radio frequency needle. It is suitable for temperature detection of the cold circulation radio frequency needle in the two working modes during treatment, thereby improving the accuracy of temperature control during the treatment process. BRIEF DESCRIPTION OF THE DRAWINGS

[0037] Figure 1 This is a connection diagram of the cold cycle radio frequency needle temperature calibration device provided in Example 1 of the present invention.

[0038] Figure 2 This is a three-dimensional diagram of the radio frequency needle holder provided in the first embodiment of the present invention.

[0039] Figure 3 This is a flow chart of the cold cycle radio frequency needle temperature calibration method provided in the second embodiment of the present invention.

[0040] Figure 4 for Figure 3 Flowchart of step (5) in FIG. DETAILED DESCRIPTION

[0041] The specific implementation of the present invention is further described below in conjunction with the accompanying drawings. For the sake of convenience, the above, below, left, right, front, and back directions may be defined in this application to facilitate the clear description of the relative position relationship of the structure, and are not used to limit the actual direction of the product during production, use, and sales. The specific implementation of the present invention is further described below in conjunction with the accompanying drawings:

[0042] Embodiment 1

[0043] See also Figure 1 , Figure 2 The present embodiment provides a cold cycle radio frequency needle temperature calibration device, including a constant temperature water tank 11, a radio frequency needle holder 12, an interface module, a chiller, a controller, a computer and an interaction module.

[0044] The RF needle rack 12 is arranged in the constant temperature water tank 11, and a plurality of RF needle placement positions 121 are arranged on the RF needle rack 12, which are used to place the cold cycle RF needle 20 when performing temperature calibration. The interface module is provided with a plurality of RF needle interfaces, a chiller control end, a controller connection end and a relay, and the relay can be a PLC (programmable logic controller) or an ordinary relay, which is used to select / cancel the cold cycle RF needle 20 to be calibrated when calibrating a plurality of cold cycle RF needles 20 at the same time. The RF needle interface can be connected to the signal connection end of the cold cycle RF needle 20, and is used to control the cold cycle RF needle 20 and receive the temperature signal transmitted back by the cold cycle RF needle 20; the chiller control end is connected to the controlled end of the chiller, and is used to control the chiller (as other feasible technical solutions, the controlled end of the chiller can also be connected to the computer or controller, or directly connected to the power supply); the controller connection end is connected to the controller, and is used to receive the control signal transmitted by the controller and the detection signal transmitted back to the controller. The water chiller is also provided with a plurality of circulating water interfaces, which are connected to the cooling interface of the cold circulation RF needle 20, and are used to provide cold circulation water to the cold circulation RF needle 20. The computer is respectively connected to the interactive module, the controller and the constant temperature water tank 11 (as other feasible technical solutions, the constant temperature water tank 11 can also be connected to the controller or the interface module, or directly connected to the power supply). The interactive module is a touch display, and the touch display is used to display the detection data obtained by the computer, and to operate the computer and input detection parameters into the computer. The controller receives the detection parameters from the computer, converts them into control signals suitable for the hardware, and transmits them to the interface module; and restores the detection signals returned by the interface module into detection data suitable for computer processing, and transmits them to the computer.

[0045] When the cold circulation radio frequency needle temperature calibration device is used for temperature calibration, the cooling interface of the cold circulation radio frequency needle 20 is connected to the circulating water interface of the cooling machine, the signal connection end of the cold circulation radio frequency needle 20 is connected to the radio frequency needle interface of the interface module, and the cold circulation radio frequency needle 20 is placed on the radio frequency needle placement position 121 of the radio frequency needle holder 12, and one end of the cold circulation radio frequency needle 20 is inserted into the liquid of the constant temperature water tank 11. By setting different temperatures for the liquid in the constant temperature water tank 11, combined with the temperature value detected by the cold circulation radio frequency needle 20 displayed in the touch display, the temperature calibration function of the radio frequency needle in the two working modes of not passing cold circulation water and passing cold circulation water is calculated respectively, so as to accurately control the temperature during the treatment process. By setting multiple radio frequency needle placement positions 121, radio frequency needle interfaces and relays, multiple cold circulation radio frequency needles 20 can be calibrated at the same time, and a corresponding temperature calibration function is generated for each calibrated cold circulation radio frequency needle 20.

[0046] Embodiment 2

[0047] See also Figure 3 , Figure 4 This embodiment provides a cold cycle radio frequency needle temperature calibration method, using the cold cycle radio frequency needle temperature calibration device provided in the first embodiment, including the following steps:

[0048] (1) Connect the signal connection end of the cold circulation RF needle to the RF needle interface of the interface module, and connect the cooling interface to the circulating water interface of the chiller;

[0049] (2) placing the cold circulation radio frequency needle on the radio frequency needle holder, and inserting one end of the cold circulation radio frequency needle into the liquid in the constant temperature water tank;

[0050] (3) starting the cold cycle radio frequency needle temperature calibration device;

[0051] (4) starting the chiller;

[0052] (5) Perform cold cycle RF needle temperature calibration.

[0053] (5a) Setting the temperature of the thermostatic water tank to 20°C (T1), and waiting for the liquid temperature in the water tank to reach a preset temperature;

[0054] (5b) the computer sends a test command to the controller not to pass cold circulating water;

[0055] (5c) Wait and determine whether the controller returns the correct test data TS1; if so, proceed to the next step; if not, continue waiting;

[0056] (5d) setting the temperature of the constant temperature water tank to 50° C. (T2) and waiting for the liquid temperature in the water tank to reach a preset temperature;

[0057] (5e) the computer sends a cold circulating water test command to the controller;

[0058] (5f) Wait and determine whether the controller returns the correct test data TS2; if so, proceed to the next step; if not, continue waiting;

[0059] (5g) Setting the temperature of the constant temperature water tank to 100° C. (T3), and waiting for the temperature of the liquid in the water tank to reach a preset temperature;

[0060] (5h) Repeat steps (5b) and (5c) to obtain test data TS3 according to T3;

[0061] (5i) Setting the temperature of the constant temperature water tank to 90° C. (T4) and waiting for the liquid temperature in the water tank to reach a preset temperature;

[0062] (5j) Repeat steps (5e) and (5f) to obtain test data TS4 according to T4;

[0063] (5k) Substitute T1, TS1, T3, and TS3 into the original temperature calibration function to obtain the temperature calibration function parameters K1 and B1 when no cold circulating water is introduced; substitute T2, TS2, T4, and TS4 into the original temperature calibration function to obtain the temperature calibration function parameters K2 and B2 when cold circulating water is introduced;

[0064] (51) Based on the calculated K1, B1, K2, and B2, when using the cold circulation radio frequency needle, the temperature calibration function parameters applicable to the needle are selected according to whether cold circulation water is passed through the needle.

[0065] Assume that the original temperature calibration function of the cold circulation radio frequency needle is T = K * TS + B. Assume that the parameters K and B are K1 and B1 when the cold circulation water is not passed through the test, that is, when the cold circulation water is not passed through the test, the temperature calibration function of the cold circulation radio frequency needle is T = K1 * TS + B1, substitute T1 and T3 into T, substitute TS1 and TS3 into TS, and obtain the formula T1 = K1 * TS1 + B1, T3 = K1 * TS3 + B1, solve the two-variable linear equation group to obtain the values ​​of K1 and B1, and obtain the temperature calibration function of the cold circulation radio frequency needle when the cold circulation water is not passed through the test. Assume that the parameters K and B are K2 and B2 when the cold circulating water test is passed, that is, when the cold circulating water test is passed, the temperature calibration function of the cold circulating radio frequency needle is T = K2*TS+B2, substitute T2 and T4 into T, substitute TS2 and TS4 into TS respectively, and obtain the formula T2 = K2*TS2+B2, T4 = K2*TS4+B2, solve the two-variable linear equation group to obtain the values ​​of K2 and B2, and obtain the temperature calibration function of the cold circulating radio frequency needle when the cold circulating water test is passed.

[0066] As another feasible technical solution, the value of T1 may be the same as that of T2 or T4, and the value of T3 may be the same as that of T4 or T2, but the value of T1 is different from that of T3, and the value of T2 is different from that of T4.

[0067] As another feasible technical solution, the order of the steps of obtaining the TS1, TS2, TS3, and TS4 can be changed according to actual needs.

[0068] The temperature calibration function of the calibrated cold circulation radio frequency needle in two working modes, without cold circulation water and with cold circulation water, is obtained. When the cold circulation radio frequency needle is used for treatment, the working mode adopted by the cold circulation radio frequency needle is selected, and the treatment equipment applies the corresponding temperature calibration function to accurately obtain the actual temperature value during the treatment process.

[0069] The above embodiments are only for full disclosure rather than limitation of the present invention. Any replacement of equivalent technical features that can be obtained based on the creative purpose of the present invention without creative work should be regarded as the scope of disclosure of this application.

Claims

1. A cold cycle radio frequency needle temperature calibration device, characterized in that: It includes a temperature sensor, a radio frequency needle holder, a constant temperature water tank, an interface module, a chiller, a controller, a computer and an interactive module, wherein the temperature sensor is arranged at the needle tip of the cold circulation radio frequency needle, the radio frequency needle holder is arranged in the constant temperature water tank, the controller is electrically connected to the computer and the interface module respectively, and the interactive module is connected to the computer; when performing temperature calibration, the signal connection end of the cold circulation radio frequency needle is connected to the radio frequency needle interface of the interface module, the cooling interface is connected to the circulating water interface of the chiller, and one end of the cold circulation radio frequency needle is inserted into the liquid of the constant temperature water tank, the temperature value detected by the cold circulation radio frequency needle is compared with the liquid temperature value of the constant temperature water tank, and the temperature calibration function of the cold circulation radio frequency needle in two working modes, that is, without cold circulation water and with cold circulation water, is calculated respectively, and the temperature calibration of the cold circulation radio frequency needle is performed according to the temperature calibration function.

2. The cold cycle radio frequency needle temperature calibration device according to claim 1, characterized in that: At least one radio frequency needle placement position is provided on the radio frequency needle holder, and when temperature calibration is performed, the cold cycle radio frequency needle is placed in the radio frequency needle placement position.

3. The cold cycle radio frequency needle temperature calibration device according to claim 1, characterized in that: The RF pin interface of the interface module and the circulating water interface of the chiller are both multiple and are used to connect multiple cold circulation RF pins at the same time.

4. The cold cycle radio frequency needle temperature calibration device according to claim 3, characterized in that: The interface module is provided with a relay for selecting / deselecting the cold cycle RF needle to be calibrated.

5. The cold cycle radio frequency needle temperature calibration device according to any one of claims 1 to 4, characterized in that: The controlled end of the chiller is electrically connected to an external power source or the controller / interface module / computer, and the controller controls the start and stop or working efficiency of the chiller.

6. The cold cycle radio frequency needle temperature calibration device according to any one of claims 1 to 4, characterized in that: The constant temperature water tank is electrically connected to an external power source or the controller / interface module / computer, and the controller controls the start and stop or temperature of the constant temperature water tank.

7. A cold cycle radio frequency needle temperature calibration method, characterized in that: The cold cycle radio frequency needle temperature calibration device according to any one of claims 1 to 6 comprises the following steps: (1) Connect the signal connection end of the cold circulation RF pin to the RF pin interface of the interface module, and connect the cooling interface to the circulating water interface of the chiller; (2) placing the cold circulation radio frequency needle on the radio frequency needle holder, and inserting one end of the cold circulation radio frequency needle into the liquid in the constant temperature water tank; (3) starting the cold cycle radio frequency needle temperature calibration device; (4) starting the chiller; (5) Perform cold cycle RF needle temperature calibration.

8. The cold cycle radio frequency needle temperature calibration method according to claim 7, characterized in that: The step (5) comprises the following steps: (5a) Setting the temperature of the constant temperature water tank to T1, and waiting for the temperature of the liquid in the water tank to reach a preset temperature; (5b) The computer sends a test command to the controller not to supply cold circulating water; (5c) Wait and determine whether the controller returns the correct test data TS1; if so, proceed to the next step; if not, continue waiting; (5d) Setting the temperature of the constant temperature water tank to T2, and waiting for the temperature of the liquid in the water tank to reach a preset temperature; (5e) The computer sends a test command to the controller to introduce cold circulating water; (5f) Wait and determine whether the controller returns the correct test data TS2; if so, proceed to the next step; if not, continue waiting; (5g) Setting the temperature of the constant temperature water tank to T3, and waiting for the temperature of the liquid in the water tank to reach a preset temperature; (5h) Repeat steps (5b) and (5c) to obtain test data TS3 based on T3; (5i) Setting the temperature of the constant temperature water tank to T4, and waiting for the temperature of the liquid in the water tank to reach a preset temperature; (5j) Repeat steps (5e) and (5f) to obtain test data TS4 according to T4; (5k) Substitute T1, TS1, T3, and TS3 into the original temperature calibration function to obtain the temperature calibration function parameters K1 and B1 when no cold circulating water is introduced; substitute T2, TS2, T4, and TS4 into the original temperature calibration function to obtain the temperature calibration function parameters K2 and B2 when cold circulating water is introduced; (51) Based on the calculated K1, B1, K2, B2, when using the cold circulation radio frequency needle, the temperature calibration function parameters applicable to the needle are selected according to whether cold circulation water is passed through the needle.

9. The cold cycle radio frequency needle temperature calibration method according to claim 8, characterized in that: The T1≠T3 and T2≠T4.

10. The cold cycle radio frequency needle temperature calibration method according to claim 8 or 9, characterized in that: The original temperature calibration function is T=K*TS+B.

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