Automatic puncture device for urine tester reagent capsule

Abstract

The present invention relates to an automatic puncture device for a urine tester reagent capsule, which adds a puncture piece to a valve core so that the valve core drives the puncture piece to puncture a sealing film of a reagent capsule. Since a corresponding sampling valve core is separately installed at the position of each reagent capsule, automatic puncture can be achieved while also avoiding cross contamination between reagents.

Description

Technical Field

[0001] The invention relates to the technical field of urine testing instruments, and in particular to an automatic puncturing device for a reagent capsule of a urine testing instrument. Background Art

[0002] As human life expectancy increases, the importance of health care and maintenance has received more and more attention. Urine can reflect a person's health status to a certain extent. Quantitative analysis of urine components can help understand diseases such as pancreas and kidneys. Urine testing has become one of the indispensable items in routine testing in medical institutions, and dry chemical urine testing analyzers have become important instruments for medical institutions.

[0003] At present, the reagents of urine testers need to be stored in the test kit in a thin film package because they need to be stored in temperature, humidity, light and oxygen. When used with a microfluidic system, the thin film sealing the test kit needs to be opened manually before adding and using. The whole operation is relatively complicated and there is also a risk of reagent spillage. If the reagent is installed once and can be reused multiple times, there is also a risk that the film will not be able to be well sealed with the device port after opening. Especially when there are multiple different reagents in the system, they need to be packaged separately, and when used separately, the unsealing process is more troublesome and there is a risk of cross contamination. Summary of the invention

[0004] The purpose of the present invention is to provide a urine test instrument reagent capsule automatic puncturing device which can automatically puncture the reagent capsule sealing film.

[0005] To achieve the above purpose, the technical solution adopted by the present invention is as follows:

[0006] A urine test instrument reagent capsule automatic puncture device, comprising a urine test instrument body and a reagent kit positioned and installed on the urine test instrument body, the urine test instrument body having a detection device and a valve, the detection device comprising a flow channel plate and a detection module, the flow channel plate is provided with a flow channel and a test pit, the test pit is connected to the flow channel, the detection reagent and the sample can flow from the flow channel into the test pit, and the detection module installed at the corresponding position of the test pit performs measurement of relevant parameters; the valve comprises a valve body and a plurality of valve cores, the valve body is provided with a plurality of main flow channels penetrating the valve body and sequentially spaced along the length extension direction of the valve body, each of the main flow channels is provided with a flow outlet connected to the flow channel; one end of each of the valve cores can be slidably installed in a corresponding one of the main flow channels and can slide along the main flow channel, and the other end extends out of the valve body, the valve core can be operated to seal Seal or open the outflow port; the test kit includes a mounting disk and a plurality of reagent capsules mounted on the mounting disk, the mounting disk has a plurality of drainage holes radially penetrating the mounting disk body, and each of the drainage holes is arranged corresponding to a reagent capsule, so that the reagent in the reagent capsule can flow into the flow channel through the drainage hole, and each of the reagent capsules includes a capsule body with a cavity and a sealing film sealed at the opening of the cavity; each drainage hole of the mounting disk is arranged opposite to a main flow channel on the valve body, and a piercing member is installed on each of the valve cores, when the mounting disk is positioned and installed on the urine test instrument body, the axial movement of the valve core along the main flow channel drives the piercing member to pierce the sealing film of the reagent capsule at the corresponding position on the mounting disk, so that the reagent in the reagent capsule can flow out from the seal of the reagent capsule.

[0007] In one embodiment, the puncture member includes a puncture tip and a rod, and two ends of the rod are respectively connected to the puncture tip and the end surface of the valve core facing the reagent capsule.

[0008] In one embodiment, the puncture tip is provided with a plurality of inclined facets.

[0009] In one embodiment, the piercing protrusion is a boss formed on the rod, and the projection of the piercing protrusion along its axial direction completely covers the rod.

[0010] In one embodiment, the sealing film of the reagent capsule is an aluminum film.

[0011] In one embodiment, a sensor and a control device are further provided on the urine testing instrument body, and a trigger corresponding to the sensor is provided on the reagent kit. The sensor is connected to the control device. When the reagent kit is positioned and installed on the urine testing instrument body, the control device can determine whether the reagent kit is correctly installed based on the information obtained from the sensor.

[0012] In one embodiment, the sensor is a Hall sensor and the trigger is a magnet.

[0013] The present invention adopts the above technical solution, which has the beneficial effect that the automatic puncture device for the urine test instrument reagent capsule provided by the present invention adds a puncture piece on the valve core, so that the valve core drives the puncture piece to puncture the sealing film of the reagent capsule. Since a corresponding sampling valve core is separately installed at the position of each reagent capsule, automatic puncture can be achieved while also avoiding cross contamination between reagents. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 The figure shows a schematic diagram of the appearance structure of a urine test instrument.

[0015] Figure 2 A schematic diagram showing the internal components of a urine test instrument.

[0016] Figure 3 A schematic diagram of a flow channel plate is shown.

[0017] Figure 4 A schematic diagram of the valve is shown.

[0018] Figure 5 A schematic diagram of the mounting plate is shown.

[0019] Figure 6 A cross-sectional schematic diagram showing the reagent kit being positioned and installed on the urine test instrument body is shown.

[0020] Figure 7 A schematic diagram of a valve core and a piercing member on the valve core is shown. DETAILED DESCRIPTION

[0021] The preferred embodiments of the present invention will be described in detail below in conjunction with the accompanying drawings so that the purpose, features and advantages of the present invention can be more clearly understood. It should be understood that the embodiments shown in the accompanying drawings are not intended to limit the scope of the present invention, but are only intended to illustrate the essential spirit of the technical solution of the present invention.

[0022] In the following description, certain specific details are set forth for the purpose of illustrating various disclosed embodiments to provide a thorough understanding of the various disclosed embodiments. However, those skilled in the relevant art will recognize that the embodiments may be practiced without one or more of these specific details. In other cases, well-known devices, structures, and techniques associated with the present application may not be shown or described in detail to avoid unnecessarily obscuring the description of the embodiments.

[0023] Unless the context requires otherwise, throughout the specification and claims, the word "comprise" and variations such as "include" and "have" should be construed in an open, inclusive sense, ie, should be interpreted as "including, but not limited to."

[0024] References throughout the specification to "one embodiment" or "an embodiment" indicate that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least one embodiment. Thus, the appearances of "in one embodiment" or "in an embodiment" in various places throughout the specification are not necessarily all referring to the same embodiment. Furthermore, the particular features, structures, or characteristics may be combined in any manner in one or more embodiments.

[0025] As used in this specification and the appended claims, the singular forms "a," "an," and "the" include plural referents unless the context clearly dictates otherwise. It should be noted that the term "or" is generally employed in its sense including "and / or" unless the context clearly dictates otherwise.

[0026] In the following description, in order to clearly show the structure and working mode of the present invention, many directional words will be used for description, but the words "front", "back", "left", "right", "outside", "inside", "outward", "inward", "up", "down", etc. should be understood as convenient terms and should not be understood as restrictive terms.

[0027] In addition, the terms "horizontal", "vertical", "overhanging" and the like do not mean that the components are required to be absolutely horizontal or overhanging, but can be slightly tilted. For example, "horizontal" only means that its direction is more horizontal than "vertical", and does not mean that the structure must be completely horizontal, but can be slightly tilted.

[0028] In the description of this application, it should also be noted that, unless otherwise clearly specified and limited, the terms "set", "install", "connect", and "connect" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two elements. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to specific circumstances.

[0029] This embodiment provides an automatic puncture device for a urine test instrument reagent capsule, comprising a urine test instrument body 1 and a reagent kit 2 .

[0030] Among them, see Figure 1-Figure 4 The urine testing instrument body 1 provided in this embodiment includes an outer shell 10 and a sampling device 11, a detection device 12, a control device 13, a driving mechanism 14, a pump 15 and a valve 16 installed in the outer shell 10.

[0031] Among them, the sampling device 11 is used to collect samples, such as urine. The sampling device 11 includes a sampling port 111 and a sampling tube 112 located on the outer shell 10. The pump 15 is controlled and connected to the sampling tube 112 to transport the sample collected by the sampling tube 112 to the detection device 12 for detection. The detection device 12 includes a flow channel plate 121 and a detection module 122. The flow channel plate 121 is provided with a flow channel 1211 and a test pit 1212, and the test pit 1212 is connected to the flow channel 1211. The detection reagent and the sample collected by the sampling device 11 can flow from the flow channel 1211 into the test pit 1212, and the detection module 122 installed at the position corresponding to the test pit 1212 measures relevant parameters, such as detecting urine to obtain human body related parameters.

[0032] The control device 13 is used to control the operation of the entire urine tester. It is electrically connected to the pump 15, the drive mechanism 14 and the detection device 12, and can control the operation of the pump 15, the drive mechanism 14 and the detection device 12. The valve 16 is used to control the opening and closing of various reagent kits. The drive mechanism 14 is used to drive the valve core corresponding to the valve 16 to open or close the valve 16, thereby opening the reagent kit to release the reagent, or closing the reagent kit.

[0033] The valve 16 includes a valve body 161 and a plurality of valve cores 162. The valve body 161 is provided with a plurality of main flow channels 1611 which penetrate the valve body 161 and are sequentially spaced apart along the length extension direction of the valve body 161. Each main flow channel 1611 is provided with a flow outlet 1612 which is connected to the flow channel 1211. One end of each valve core 162 is slidably installed in a corresponding main flow channel 1611 and can slide along the main flow channel 1611, and the other end extends out of the valve body 161. The valve core 162 can operably seal or open the flow outlet 1612.

[0034] In order to avoid repeated description of the same structural device, the content of the patent application with application number CN202122547895.9 is cited here. The specific structures of the sampling device 11, the detection device 12, the control device 13, the driving mechanism 14, the pump 15 and the valve 16 and the operating principle of the control device 13 controlling the pump 15, the driving mechanism 14 and the detection device 12 can be found in the corresponding part of the content of the patent application CN202122547895.9.

[0035] See also Figure 2 and Figure 5The reagent kit 2 includes a mounting plate 21 and a plurality of reagent capsules 22 mounted on the mounting plate 21. The outer shape of the mounting plate 21 is matched with the valve body 161. For example, the valve body 161 shown in the figure of the present embodiment is annular. Therefore, the outer shape of the mounting plate 21 is arc-shaped, but it is not limited thereto. It can also be other outer shapes, such as a strip shape. The mounting plate 21 has a plurality of drainage holes 211 radially penetrating the mounting plate body, and each drainage hole 211 is arranged corresponding to a reagent capsule 22, so that the reagent in the reagent capsule 22 can flow into the flow channel of the flow channel plate 121 through the drainage hole 211. Each reagent capsule 22 includes a capsule body having a cavity 221 and a sealing film 222 sealed at the opening of the cavity. The cavity of the reagent capsule 22 contains various suitable detection reagents for testing samples, such as urine, including but not limited to reagents used for routine testing, such as urine pH, urine white blood cells (WBC / LEU), urine nitrite (NIT), urine protein (PRO), glucose (GLU), urobilinogen (URO / UBG), ketone bodies (KET), occult blood (BLU), bilirubin (BIL), ascorbic acid (VC), salts, creatinine (CrE), and reagents that can also be used for tumor markers, such as alpha-fetoprotein, carcinoembryonic antigen, albumin, urine β2-microglobulin, etc., and reagents for detecting microorganisms, such as nicotine, ethanol, vitamin C, etc.

[0036] See also Figure 6 Each drainage hole 211 of the mounting disk 21 is arranged opposite to a main flow channel 1611 on the valve body 161, and each valve core 162 has a piercing member 163. When the mounting disk 21 is positioned and installed on the urine test instrument body 1, the movement of the valve core 162 can enable the piercing member 163 on the valve core 162 to pierce the sealing film 222 of the reagent capsule 22 at the corresponding position on the mounting disk 21, so that the reagent in the reagent capsule 22 can flow out from the sealing port of the reagent capsule 22.

[0037] Since each valve core 162 corresponds to a reagent capsule, when the reagent kit 2 is positioned and assembled on the urine test instrument body 1, the sealing film on each reagent capsule can be pierced by the piercing member 163 of the valve core 162 at the corresponding position. Since each valve core 162 is independent of each other, cross contamination between reagents will not occur. In addition, each valve core 162 can be controlled individually by the driving mechanism 14, so the piercing and unsealing operation can be performed when the reagent in the corresponding reagent capsule needs to be used, so that each reagent can be sealed most effectively.

[0038] See also Figure 7In one embodiment, the puncture member 163 includes a puncture protrusion 1631 and a rod 1632, wherein the two ends of the rod 1632 respectively connect the puncture protrusion 1631 and the end surface of the valve core 162 facing the reagent capsule. The puncture protrusion 1631 may be provided with a plurality of inclined facets, and the number of inclined facets of the puncture protrusion 1631 and the inclination of the inclined facets relative to the main axis of the puncture protrusion 1631 may be adjusted according to the different material properties of the sealing film. Preferably, the projection of the puncture protrusion 1631 along its axial direction completely covers the rod, that is, the puncture protrusion 1631 is a boss formed on the rod 1632. During puncture, the entire puncture protrusion 1631 pierces the sealing film. When the valve core 162 retreats, the puncture protrusion 1631 also has an effect similar to a barb, which will expand the damaged area of ​​the sealing film so that the reagent can flow out of the reagent capsule more smoothly. More preferably, the sealing film of the reagent capsule is an aluminum film.

[0039] In one embodiment, a sensor is further provided on the urine test instrument body 1, and a trigger corresponding to the sensor is provided on the reagent kit 2. The sensor is connected to the control device 13. When the reagent kit 2 is positioned and installed on the urine test instrument body 1, the trigger cooperates with the sensor and the sensor sends the information obtained to the control device 13. The control device 13 can determine whether the reagent kit 2 is correctly installed based on the information it obtains. When the reagent kit 2 has been correctly installed on the urine test instrument body 1, the control device 13 will allow the driving mechanism 14 to drive the valve core 162 of the valve 16 to puncture the sealing film on the corresponding reagent capsule to avoid damage to the device or injury to personnel due to the driving mechanism 14 accidentally driving the valve core 162 to operate when the reagent kit is not installed or is incorrectly installed.

[0040] The sensor may be a Hall sensor, and its corresponding trigger is a magnet. When the reagent box 2 is positioned and installed on the urine test instrument body 1, the Hall sensor can sense the change in the magnetic field of the magnet on the reagent box, thereby determining whether the reagent box is correctly installed. The sensor may also be an existing sensor such as a proximity sensor or a photoelectric sensor, and the trigger is an inductor installed on the reagent box or the reagent box itself.

[0041] See also Figure 4, a return spring 163 is provided on the valve core 162. When the valve core 162 is only acted upon by the return spring 163, that is, when the driving motor does not actuate the valve core 162, the valve core 163 and the piercing member 1621 mounted on the valve core 162 do not extend out of the main flow channel 1611, so that the piercing member 1621 does not extend out of the flow channel 1611 when the valve core is reset, thereby preventing the piercing member from accidentally causing damage to the reagent and the user. Preferably, the force exerted by the return spring 163 on the valve core 162 is greater than the no-load resistance of the driving mechanism 14, so as to prevent the valve core 161 from accidentally actuating when the driving mechanism is powered on, thereby preventing damage to the device or injury to personnel.

[0042] The preferred embodiments of the present invention have been described in detail above, but it should be understood that after reading the above teachings of the present invention, those skilled in the art may make various changes or modifications to the present invention. These equivalent forms also fall within the scope defined by the appended claims of this application.

Claims

1. An automatic puncture device for a urine test instrument reagent capsule, comprising a urine test instrument body and a reagent kit positioned and installed on the urine test instrument body, the urine test instrument body having a detection device and a valve, the detection device comprising a flow channel plate and a detection module, the flow channel plate having a flow channel and a test pit, the test pit being connected to the flow channel, the detection reagent and the sample flowing from the flow channel into the test pit, and being installed in the detection module corresponding to the position of the test pit to measure relevant parameters; the valve comprising a valve body and a plurality of valve cores, the valve body being provided with a plurality of main flow channels penetrating the valve body and sequentially spaced along the length extension direction of the valve body, each of the main flow channels being provided with a flow outlet connected to the flow channel; one end of each of the valve cores can be slidably installed in a corresponding main flow channel and can slide along the main flow channel, and the other end extends out of the valve body, the valve core can be operatively sealed or opened the flow outlet; characterized in that: The reagent kit comprises a mounting plate and a plurality of reagent capsules mounted on the mounting plate, the mounting plate having a plurality of drainage holes radially penetrating the mounting plate body, and each of the drainage holes is arranged corresponding to a reagent capsule, so that the reagent in the reagent capsule can flow into the flow channel through the drainage hole, and each of the reagent capsules comprises a capsule body having a cavity and a sealing film sealed at the opening of the cavity; each drainage hole of the mounting plate is arranged opposite to a main flow channel on the valve body, and a piercing member is installed on each of the valve cores, and when the mounting plate is positioned and mounted on the urine test instrument body, the axial movement of the valve core along the main flow channel drives the piercing member to pierce the sealing film of the reagent capsule at the corresponding position on the mounting plate, so that the reagent in the reagent capsule can flow out from the sealing opening of the reagent capsule; The puncture member includes a puncture tip and a rod, and two ends of the rod are respectively connected to the puncture tip and the end surface of the valve core facing the reagent capsule; The urine test instrument body is also provided with a sensor and a control device, the reagent kit is provided with a trigger corresponding to the sensor, the sensor is connected to the control device, and when the reagent kit is positioned and installed on the urine test instrument body, the control device can determine whether the reagent kit is correctly installed based on the information obtained from the sensor.

2. The automatic puncture device for urine tester reagent capsule according to claim 1, characterized in that: The puncture tip is provided with a plurality of inclined small planes.

3. The automatic puncture device for urine tester reagent capsule according to claim 1, characterized in that: The puncture tip is a boss formed on the rod, and the projection of the puncture tip along its axial direction completely covers the rod.

4. The automatic puncture device for urine tester reagent capsule according to claim 1, characterized in that: The sealing film of the reagent capsule is an aluminum film.

5. The automatic puncture device for urine tester reagent capsule according to claim 1, characterized in that: The valve core is provided with a return spring, and when the valve core is only subjected to the force of the return spring, the valve core and the piercing member installed on the valve core do not extend out of the main flow channel.

6. The automatic puncture device for urine tester reagent capsule according to claim 5, characterized in that: It also includes a driving mechanism for pushing the valve core to move. The driving mechanism is electrically connected to the control device, and the force exerted by the return spring on the valve core is greater than the no-load resistance of the driving mechanism.

7. The automatic puncture device for urine tester reagent capsule according to claim 1, characterized in that: The sensor is a Hall sensor, and the trigger is a magnet.

8. The automatic puncture device for urine tester reagent capsule according to claim 1, characterized in that: The sensor is a proximity sensor or a photoelectric sensor, and the trigger is the reagent box itself.

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