A syringe pump feeding system and a control method thereof

Abstract

The application discloses a kind of control method of injection pump feeding system, to provide a kind of injection pump feeding system's control method with simple structure, buffering effect is good, and it has cleaning function and strong practicality, its technical scheme main point is to the detection of polyphase valve A and polyphase valve B, ensure that current channel is consistent with set channel, improve accuracy, in the opening of injection pump, and carry out suction, until suction is completed, at this time, close polyphase valve A feed channel, judge whether the current channel of required polyphase valve B is consistent with set channel, if not, manually move polyphase valve B to set channel and adjust whether it is in open state, if yes, under the driving of injection pump, reagent in glass container is transferred to reaction bottle, using injection pump as power source, simple structure can control the amount of suction, strong practicality, simple structure, the application is suitable for laboratory automatic feeding technical field.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of laboratory automatic feeding, more particularly, it relates to an injection pump feeding system and a control method thereof. BACKGROUND

[0002] In some special occasions, the occupation realized through the Internet and the computer can also be normally worked at home. However, for some special enterprises, such as pharmaceutical and chemical enterprises, work needs to be carried out in the laboratory, and the conventional online platform cannot meet this demand. Under this background, the shared experiment platform emerges as the times require, which is used to solve the problem of collaborative experiment in multiple places. In addition, with the gradual popularization of the shared laboratory platform, various types of implementation projects can be realized through the shared laboratory platform.

[0003] As for the offline laboratory, when publishing the task on the shared laboratory platform, the automatic feeding operation also needs to be carried out to ensure the rapid progress of the experiment, and the precision needs to be guaranteed to improve the accuracy of the laboratory. SUMMARY

[0004] In view of the deficiencies in the prior art, the purpose of the present application is to provide a control method for an injection pump feeding system, which has the advantages of simple structure, good pressure relief effect, cleaning function and strong practicality.

[0005] To achieve the above-mentioned purpose, the present application provides the following technical scheme: a control method for an injection pump feeding system, comprising a transmission layer, an offline operation platform in communication connection with the transmission layer, and the offline operation platform being in communication connection with an offline laboratory, comprising the following steps: S1, the transmission layer issues data, the offline operation platform receives the instruction and issues it to the offline laboratory;

[0006] S2, the control system of the offline laboratory performs traversal detection on each detection unit to determine whether feeding is needed, and sets the feeding application point of the detection unit needing feeding to 1;

[0007] S3, after the traversal, the feeding application points of each detection unit are traversed, and each detection unit is sequentially detected, and the detection unit entering the feeding process is detected, and the next detection unit is detected after the process is completed;

[0008] S4, it is determined whether the feeding amount is greater than 0 and the set channel of each multiphase valve detection unit is greater than 0 at the same time;

[0009] S5, if yes, the communication points of each required multiphase valve A, B detection unit, the communication point of the injection pump and the required balance communication point are set to 1, and the feeding process is performed; if no, return to S3 to traverse the feeding application points of each detection unit;

[0010] S6, record the current balance value as the initial value of the material, and the current balance value-the initial value of the material=the amount of material added;

[0011] S7, judge whether the current channel of the required multi-phase valve A is consistent with the set channel, if yes, go to the next step, if not, issue an instruction to switch the channel of the eight valves to the set channel.

[0012] S8, the syringe pump is turned on and starts to suck material until the syringe pump finishes sucking material;

[0013] S9, after the syringe pump finishes sucking material, the multi-phase valve A feeding channel is closed, and the current channel is set to 0;

[0014] S10, judge whether the current channel of the required multi-phase valve B is consistent with the set channel, if yes, go to the next step, if not, issue an instruction to switch the channel of the eight valves to the set channel.

[0015] S11, judge whether the set amount-the added amount is less than or equal to the current allowable error, if yes, the device detection unit completes the point setting is 1, and returns to S3 to detect the next unit, if not, continue to judge whether the syringe pump is finished, if yes, return to step S7 to take material, if not, drain the material in the syringe pump;

[0016] S12, judge whether the detection of the material taking unit is completed, if yes, return to step S2 to re-detect whether there is a unit to be fed, if not, return to S3 to continue to traverse all application points.

[0017] The application further provides that: the step S11 further includes a cleaning method, which includes the following steps: S110, close the syringe pump, switch the multi-phase valve A to the nitrogen port, and switch the multi-phase valve B to the corresponding phase of the reaction bottle;

[0018] S111, open the nitrogen valve, press the reagent in the pipeline to empty, and the nitrogen inlet time is between 5s-10s;

[0019] S112, close the nitrogen valve, close the multi-phase valve A, and finally close the multi-phase valve B;

[0020] S113, complete the cleaning operation.

[0021] The application further provides that: the gas pressure during the nitrogen inlet is between 20MPa-50MPa.

[0022] The application further provides that: the amount of material taken by the syringe pump each time is between 5-10ml, and the pressure control of the syringe pump is between 10MPa-50MPa.

[0023] The injection pump controls pressure through a pressure controller, and the pressure adjustment method of the injection pump is as follows: when the added material amount is greater than the set amount of material -10, the injection pump pressure is controlled between 40 MPa and 50 MPa;

[0024] When the added material amount is greater than the set amount of material -5, the injection pump pressure is controlled between 20 MPa and 40 MPa.

[0025] When the added material amount is greater than the set amount of material -1, the injection pump pressure is controlled between 10 MPa and 20 MPa.

[0026] By adopting the above technical scheme, the beneficial effects are: 1. In order to correspond to multiple reagent bottles and reaction bottles at the same time, the addition of reagents is controlled by multi-phase valves A and B, the distribution accuracy of reagents is high, the structure is simple, and the practicability is strong. Moreover, through the double traversal mode, the monitoring accuracy of the multi-phase valves A and B is realized, and the stability is strong.

[0027] 2. The multi-phase valves A and B are detected to ensure that the current channel is consistent with the set channel, improve the accuracy, open the injection pump, and perform material suction until the material suction is completed. At this time, the multi-phase valve A feeding channel is closed, and it is judged whether the current channel of the required multi-phase valve B is consistent with the set channel. If not, manually move the multi-phase valve B to the set channel and adjust whether it is in the open state. If yes, under the driving of the injection pump, the reagent in the glass container is transferred to the reaction bottle. The injection pump is used as a power source, the structure is simple, the amount of material suction can be controlled, the practicability is strong, and the structure is simple.

[0028] 3. The step S11 further includes a cleaning method, which includes the following steps: first, close the injection pump, switch the multi-phase valve A to the nitrogen port, and switch the multi-phase valve B to the reaction bottle corresponding to one phase; then open the nitrogen valve, empty the reagent in the pipeline, and introduce nitrogen for 5-10s; the reagent in the pipeline can be emptied to ensure the cleaning effect, and the convenience is strong. Finally, close the nitrogen valve, close the multi-phase valve A, and close the multi-phase valve B to complete the cleaning operation. The practicability is strong, and the structure is simple.

[0029] 4. The further cleaning method also has a good cleaning effect in combination with the injection pump, and the practicability is strong, the cleaning effect is good, and the structure is simple.

[0030] The injection pump feeding system suitable for the control method comprises a plurality of scales, reagent bottles arranged on the scales, a multi-phase valve A, connecting pipes A connected with liquid outlets of the reagent bottles and input ends of the multi-phase valve A in sequence, a multi-phase valve B connected with an output end of the multi-phase valve A, a glass container arranged between the output end of the multi-phase valve A and the input end of the multi-phase valve B, an injection pump communicated with the glass container, and reaction bottles connected with each phase of the multi-phase valve B.

[0031] The injection pump feeding system further comprises an emptying mechanism, which comprises a nitrogen port arranged on the multi-phase valve A, a nitrogen pipeline communicated with the nitrogen port of the multi-phase valve A, a nitrogen valve arranged on the nitrogen pipeline, a waste liquid pipeline communicated with one phase of the multi-phase valve A, and a waste liquid bottle communicated with the waste liquid pipeline.

[0032] By adopting the technical scheme, the beneficial effects are as follows: the injection pump is used as a main power source to suck and discharge materials, the structure is simple, and the practicability is high; when the injection pump is used, the glass container is used in cooperation, the glass container has a good buffering space when the injection pump sucks materials, and the pressure is also buffered by the glass container when the injection pump discharges materials, so that the stability of the materials is ensured, the practicability is high, and the structure is simple. BRIEF DESCRIPTION OF DRAWINGS

[0033] Figure 1 The flow of the injection pump feeding system and the control method thereof Figure 1 .

[0034] Figure 2 The flow of the injection pump feeding system and the control method thereof Figure 2 .

[0035] Figure 3 The structural diagram of the injection pump feeding system and the control method thereof. DETAILED DESCRIPTION

[0036] REFERENCE Figures 1 to 3 The injection pump feeding system and the control method thereof are further described.

[0037] For ease of description, spatially relative terms, such as "upper", "lower", "left", "right", and the like, are used herein for the purpose of illustrating one element or feature's relationship to another element or feature, as illustrated in the figures. It will be understood that the spatial terms are intended to encompass different orientations of the device in use or operation, in addition to the orientation depicted in the figures. For example, if a device is inverted, elements described as being on the "lower" side of other elements or features would then be oriented on "upper" sides of the other elements or features. Thus, the exemplary term "lower" can encompass both an orientation of lower and upper, depending on the particular orientation. The devices can be positioned in other ways (rotated 90 degrees or oriented in other orientations) and the spatially relative descriptions used herein interpreted accordingly.

[0038] Moreover, terms such as "first" and "second", etc. are used herein simply to differentiate one element from another element having the same name, and do not necessarily require or imply any such actual relationship or order between or among the elements.

[0039] A control method of a syringe pump feeding system, comprising a transmission layer, an offline operation platform in communication connection with the transmission layer, the offline operation platform being in communication connection with an offline laboratory, the offline operation platform comprising a reagent bottle, a multi-phase valve A, a multi-phase valve B, a glass container and a syringe pump, comprising the following steps: S1, the transmission layer issues data, the offline operation platform receives the instruction and issues to the offline laboratory;

[0040] S2, the control system of the offline laboratory performs traversal detection on each detection unit to determine whether feeding is required, and sets the feeding application point of the detection unit requiring feeding to 1;

[0041] S3, after the traversal, the feeding application points of each detection unit are traversed again, each detection unit is sequentially detected, and the detection unit entering the feeding process is detected to the application, and the next detection unit is detected after the process is completed;

[0042] By adopting the above structure, in order to correspond to multiple reagent bottles and reaction bottles at the same time, the addition of reagents is controlled through the multi-phase valves A and B, the distribution accuracy of the reagents is high, the structure is simple, the practicality is strong, and through the double traversal mode, the monitoring accuracy effect of the multi-phase valves A and B is realized, and the stability is strong;

[0043] S4, it is determined whether the feeding addition amount is > 0 and each multi-phase valve detection unit set channel is > 0 at the same time;

[0044] S5, if yes, the communication points of each required multi-phase valve A and B detection unit, the communication points of the syringe pump and the required balance are set to 1, and the feeding process is performed; if no, return to S3 to traverse the feeding application points of each detection unit;

[0045] S6, record the current balance value as the initial value of the material, and the current balance value-the initial value of the material=the amount of material added;

[0046] S7, judge whether the current channel of the required multi-phase valve A is consistent with the set channel, if yes, go to the next step, if not, issue an instruction to switch the channel of the eight valves to the set channel.

[0047] S8, the injection pump is turned on and starts to suck material until the injection pump finishes sucking material;

[0048] S9, after the injection pump finishes sucking material, the multi-phase valve A feeding channel is closed, and the current channel is set to 0;

[0049] S10, judge whether the current channel of the required multi-phase valve B is consistent with the set channel, if yes, go to the next step, if not, issue an instruction to switch the channel of the eight valves to the set channel.

[0050] S11, judge whether the set amount-the added amount is less than or equal to the current allowable error, if yes, the device detection unit completes the point setting is 1, and returns to S3 to detect the next unit, if not, continue to judge whether the injection pump is finished, if yes, return to step S7 to take material, if not, drain the material in the injection pump;

[0051] S12, judge whether the detection of the material taking unit is completed, if yes, return to step S2 to re-detect whether there is a unit to be fed, if not, return to S3 to continue to traverse all application points.

[0052] By adopting the above structure, the multi-phase valve A and the multi-phase valve B are detected to ensure that the current channel is consistent with the set channel, improve the accuracy, turn on the injection pump and suck material until the material is finished, at this time, the multi-phase valve A feeding channel is closed, it is judged whether the current channel of the required multi-phase valve B is consistent with the set channel, if not, manually move the multi-phase valve B to the set channel and adjust whether it is in the open state, if yes, under the drive of the injection pump, the reagent in the glass container is transferred to the reaction bottle, the injection pump is used as the power source, the structure is simple, the amount of material can be controlled, and the practicability is high.

[0053] The application further sets that: the step S11 further includes a cleaning method, which includes the following steps: S110, close the injection pump, switch the multi-phase valve A to the nitrogen port, and switch the multi-phase valve B to the reaction bottle corresponding to one phase;

[0054] S111, open the nitrogen valve, press the reagent in the pipeline to be empty, and the nitrogen inlet time is between 5s-10s;

[0055] S112, close the nitrogen valve, close the multi-phase valve A, and finally close the multi-phase valve B;

[0056] S113, completing the cleaning operation.

[0057] By adopting the above structure, the step S11 further comprises a cleaning method, which comprises the following steps: first, close the injection pump, switch the multi-phase valve A to the nitrogen port, and switch the multi-phase valve B to the corresponding phase of the reaction bottle; then, open the nitrogen valve, press the reagent in the pipeline, and the nitrogen inlet time is between 5s-10s; the reagent in the pipeline can be emptied to ensure the cleaning effect, and the convenience is strong; finally, close the nitrogen valve, close the multi-phase valve A, and close the multi-phase valve B to complete the cleaning operation, which is practical and simple in structure.

[0058] The further cleaning method also has better cleaning effect in combination with the injection pump, which is practical, has good cleaning effect and simple structure.

[0059] The application is further provided that the gas pressure during nitrogen inlet is between 20MPa-50MPa.

[0060] The application is further provided that the injection pump has a material taking amount of 5-10ml each time, and the pressure of the injection pump is controlled between 10MPa-50MPa.

[0061] The application is further provided that the injection pump is controlled by a pressure controller, and the pressure adjustment method of the injection pump is as follows: when the added material amount is greater than the set amount of material-10, the pressure of the injection pump is controlled between 40MPa-50MPa.

[0062] When the added material amount is greater than the set amount of material-5, the pressure of the injection pump is controlled between 20MPa-40MPa.

[0063] When the added material amount is greater than the set amount of material-1, the pressure of the injection pump is controlled between 10MPa-20MPa.

[0064] By adopting the above adjustment method, the pressure of the injection pump is adjusted according to the added material amount, which can gradually reduce the pressure under the condition of reducing the required material, thereby forming the effect of slow pressure, which is practical and simple in structure, and has good output control effect on the material.

[0065] An injection pump feeding system suitable for the above control method comprises a plurality of scales, reagent bottles arranged on each scale, a multi-phase valve A, a connecting pipe A connected to the liquid outlet of the reagent bottle and the input end of each phase of the multi-phase valve A in turn, a multi-phase valve B connected to the output end of the multi-phase valve A, a glass container arranged between the output end of the multi-phase valve A and the input end of the multi-phase valve B, an injection pump communicated with the glass container, and each reaction bottle connected to each phase of the multi-phase valve B.

[0066] The application is further configured to further comprise a emptying mechanism, the emptying mechanism comprises a nitrogen port arranged on the multi-phase valve A, a nitrogen pipeline in communication with the nitrogen port of the multi-phase valve A, a nitrogen valve arranged on the nitrogen pipeline, a waste liquid pipeline in communication with one phase of the multi-phase valve, and a waste liquid bottle in communication with the waste liquid pipeline.

[0067] By adopting the above technical scheme, the beneficial effects are that the injection pump is used as the main power source to suck and discharge materials, the structure is simple, and the practicality is strong. Moreover, when the injection pump is used, because the injection pump is used in cooperation with the glass container, when the injection pump sucks materials, the glass container has a good buffering space. Similarly, when the injection pump discharges materials, the pressure is also buffered by the glass container, so that the stability of the materials is ensured, the practicality is strong, and the structure is simple.

[0068] The above merely describes the preferred embodiments of the application and is not intended to limit the application. Any common changes and replacements within the technical scheme of the application made by those skilled in the art shall be included in the protection scope of the application.

Claims

1. A control method of a syringe pump feeding system, comprising a transmission layer, an offline operation platform in communication connection with the transmission layer, and the offline operation platform being in communication connection with an offline laboratory, characterized in that, Comprise the following steps, S1, the transmission layer issues data, the offline operation platform accepts instruction, and issues to offline laboratory; S2, the control system of offline laboratory carries out traversal detection to each detection unit whether to need to feed, and the feeding application point of the detection unit needing to feed is set to 1; S3, after traversal, the feeding application point of each detection unit is traversed again, and each detection unit is detected in turn, and the application will enter the feeding process after detection, and the next detection unit will be detected after the process is finished; S4, judge whether the feeding addition amount is >0 and each multi-phase valve A, B detection unit set channel >0 at the same time; S5, if yes, then set each required multi-phase valve A, B detection unit communication point, syringe pump communication point and required balance communication point to 1, and carry out feeding process; if not, return to S3 to traverse the feeding application point of each detection unit; S6, before feeding, record the current balance value as the initial value of feeding, and the added material amount = the balance value in the feeding process-initial value of feeding; S7, judge whether the current channel of the required multi-phase valve A is consistent with the set channel, if yes, then enter the next step; if not, then issue instruction to the multi-phase valve A to switch the channel to the set channel; S8, the syringe pump is opened, and starts to suck material until the syringe pump finishes sucking material; S9, after the syringe pump finishes sucking material, the feeding channel of the multi-phase valve A is closed, and the current channel is set to 0; S10, judge whether the current channel of the required multi-phase valve B is consistent with the set channel, if yes, then enter the next step; If not, then issue instruction to the multi-phase valve B to switch the channel to the set channel; S11, judge whether the feeding set amount-added material amount ≤ current allowable error, if yes, then set the equipment detection unit completion point to 0, return to S3 to detect the next unit; if not, then continue to judge whether the syringe pump finishes discharging, if yes, then return to step S7 to take material; if not, then discharge the material in the syringe pump; S12, judge whether the detection of the material taking unit is finished, if yes, then return to step S2 to detect whether there is a unit needing feeding again; if not, then continue to traverse all application points in S3; It comprises several balances, reagent bottles arranged on each balance, a multi-phase valve A, a connecting pipe A connected to the liquid outlet end of the reagent bottle and each phase input end of the multi-phase valve A in turn, a multi-phase valve B connected to the output end of the multi-phase valve A, a glass container arranged between the output end of the multi-phase valve A and the input end of the multi-phase valve B, a syringe pump communicated with the glass container, and each reaction bottle connected to each phase of the multi-phase valve B. It also comprises an emptying mechanism, which comprises a nitrogen port arranged on the multi-phase valve A, a nitrogen pipeline communicated with the nitrogen port of the multi-phase valve A, a nitrogen valve arranged on the nitrogen pipeline, a waste liquid pipeline communicated with one phase of the multi-phase valve A, and a waste liquid bottle communicated with the waste liquid pipeline.

2. The control method of a syringe pump feeding system according to claim 1, wherein, The step S11 further comprises a cleaning method, which comprises the following steps: S110, close the syringe pump, switch the multi-phase valve A to the nitrogen port, and switch the multi-phase valve B to the corresponding phase of the reaction bottle; S111, open the nitrogen valve, press the reagent in the pipeline to empty, and the nitrogen inlet time is between 5s-10s. S112, close the nitrogen valve, close the multi-phase valve A, and finally close the multi-phase valve B; S113, complete the cleaning operation.

3. The control method of a syringe pump feeding system according to claim 2, wherein, The gas pressure during the nitrogen gas injection is between 20 MPa and 50 MPa.

4. The control method of a syringe pump feeding system according to claim 1, wherein, The injection pump has a material taking amount of 5-10 ml each time, and the pressure of the injection pump is controlled to be between 10 MPa and 50 MPa.

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