A disinfecting mother liquor and its raw material composition, preparation method and application

Abstract

The application discloses a disinfectant mother liquor, a raw material composition, a preparation method and application thereof. The raw material composition of the disinfectant mother liquor comprises the following components in parts by weight: 100 parts of water, 2-10 parts of a water-soluble polymer, 0.1-1 parts of a dialdehyde grafting agent and 1-6 parts of a guanidine salt polymer; wherein the mass ratio of the water-soluble polymer and the guanidine salt polymer is (1.5-8):1, and the mass ratio of the dialdehyde grafting agent and the guanidine salt polymer is (0.05-0.4):1. The guanidine salt polymer is grafted onto the water-soluble polymer, the prepared disinfectant mother liquor and disinfectant have excellent antibacterial disinfection efficacy, the antibacterial disinfection efficacy is better than that of the guanidine salt polymer with the same concentration, the antibacterial disinfection has higher durability, the bacteriostatic range is wide, the content of free guanidine salt polymer in the disinfectant mother liquor is low, the guanidine salt polymer is not easy to separate from the water-soluble polymer, the safety is high, and the disinfectant mother liquor is suitable for occasions with high safety requirements.

Description

TECHNICAL FIELD

[0001] The present application belongs to the technical field of disinfectant solution, and particularly relates to a disinfectant mother liquor, a raw material composition thereof, a preparation method and application. BACKGROUND

[0002] A healthy life has become an inevitable demand for people, and disinfectant products are an important aspect that can achieve this demand. Disinfectant products involve many fields of use, such as environmental disinfection, drinking water disinfection, food disinfection, object surface disinfection, skin disinfection, etc.

[0003] Common disinfectants include chlorine-containing, ethanol, phenol, guanidine, etc. Among them, chlorine-containing disinfectants have strong bactericidal ability, ethanol disinfectants have no residue, and guanidine disinfectants are mild and safe. However, chlorine-containing disinfectants have certain risks during transportation, storage and use, such as the reaction of chlorine-containing disinfectants with organic matter to produce organic halides such as CHCl3, which has been confirmed to be a carcinogenic substance. The bactericidal effect of ethanol disinfectants is due to its denaturation ability to proteins, and the characteristics are rapid action, but it has a greater irritation to the skin, mucous membrane, wounds and wounds, and is flammable and explosive. Guanidine disinfectants are considered to be safe and mild broad-spectrum antibacterial agents, such as polyhexamethylene biguanide hydrochloride and polyhexamethylene guanidine hydrochloride, but their disinfection performance needs to be improved.

[0004] The properties of disinfectants that are concerned include many aspects, such as excellent antibacterial disinfection ability, safety to human body and environment, durability of antibacterial disinfection performance, storage stability, non-flammability and non-explosiveness, non-corrosiveness, non-irritation (to skin, mucous membrane, wounds, etc.), low odor or no odor, etc.

[0005] In view of the defects of disinfectants on the market at present, the present field urgently needs to develop a safe, stable, non-irritating, non-corrosive, antibacterial disinfectant composition with excellent antibacterial disinfection ability and long-lasting bacteriostatic effect. SUMMARY

[0006] The technical problem to be solved by the present application is to overcome the defects of the prior art, such as poor storage stability of disinfectant solution, poor safety to human body and environment, non-durability of antibacterial disinfection performance, and limited disinfection ability, and to provide a disinfectant mother liquor, a raw material composition thereof, a preparation method and application. In the present application, guanidine salt polymer is grafted onto water-soluble polymer to obtain a disinfectant mother liquor and disinfectant with excellent antibacterial disinfection efficacy, better antibacterial disinfection efficacy than guanidine salt polymer of the same concentration, higher durability of antibacterial disinfection, wider bacteriostatic range, lower content of free guanidine salt polymer in the disinfectant mother liquor, and high safety due to the difficulty of guanidine salt polymer to separate from water-soluble polymer, which is suitable for occasions with high safety requirements.

[0007] The present application solves the above technical problems by using the following technical solutions:

[0008] The present application provides a raw material composition of a disinfectant stock solution, which comprises the following components in parts by weight: 100 parts of water, 2-10 parts of a water-soluble polymer, 0.1-1 part of a dialdehyde grafting agent, and 1-6 parts of a guanidine salt polymer;

[0009] wherein the mass ratio of the water-soluble polymer to the guanidine salt polymer is (1.5-8):1, and the mass ratio of the dialdehyde grafting agent to the guanidine salt polymer is (0.05-0.4):1.

[0010] In some embodiments, the mass ratio of the water-soluble polymer to the guanidine salt polymer is preferably (1.5-4):1, more preferably (2-4):1, and further more preferably (3-4):1, for example 2.3:1.

[0011] In some embodiments, the mass ratio of the dialdehyde grafting agent to the guanidine salt polymer is preferably (0.05-0.2):1, more preferably (0.1-0.2):1, for example 0.075:1 or 0.15:1.

[0012] In some embodiments, the water-soluble polymer can comprise at least one of water-soluble starch, polyvinyl alcohol, polyethylene glycol, and polyacrylamide, and preferably comprises water-soluble starch and / or polyvinyl alcohol.

[0013] In some embodiments, the number average molecular weight of the water-soluble polymer can be 20,000-2,000,000.

[0014] In some embodiments, the dialdehyde grafting agent can comprise at least one of glutaraldehyde, p-phenylenedimethanal, and o-phenylenedimethanal, and preferably is glutaraldehyde.

[0015] In some embodiments, the number average molecular weight of the guanidine salt polymer can be 500-30,000.

[0016] In some embodiments, the guanidine salt polymer can be a mono-guanidine salt polymer and / or a bis-guanidine salt polymer commonly used in the art.

[0017] In a preferred embodiment, the mono-guanidine salt polymer comprises a mono-guanidine salt polymer having a structure of R-NH-a-R', wherein:

[0018] a comprises at least one structural unit represented by general formula (A), Y n - selected from Cl - , Br - , HSO4 - , HCO3 - , H2PO4 - , or CH3COO - ; and Rn a structural unit selected from one or more of a structure represented by (Formula 11), a structure represented by (Formula 12), a structure represented by (Formula 13), a structure represented by (Formula 14), a structure represented by (Formula 15), a structure represented by (Formula 16), and a structure represented by (Formula 17);

[0019]

[0020] R and R', one of which is hydrogen, and the other is selected from hydrogen, a structural unit represented by (Formula 21), a structural unit represented by (Formula 22), a structural unit represented by (Formula 23), a structural unit represented by (Formula 24), or a structural unit represented by (Formula 25); preferably, R and R', one of which is hydrogen, and the other is selected from a structural unit represented by (Formula 21), a structural unit represented by (Formula 22), a structural unit represented by (Formula 23), a structural unit represented by (Formula 24), or a structural unit represented by (Formula 25);

[0021]

[0022] R3 is C4-C8 alkyl; R4 is C2-C4 alkylene; R5 is C2-C4 alkyl, substituted or unsubstituted C5-C8 cycloalkyl, benzyl, or phenethyl; and R6 is p-methylbenzenesulfonate. 12 alkyl; R4 is C2-C4 alkylene; R5 is C2-C4 alkyl, substituted or unsubstituted C5-C8 cycloalkyl, benzyl, or phenethyl; and R6 is p-methylbenzenesulfonate. 12 alkyl; R4 is C2-C4 alkylene; R5 is C2-C4 alkyl, substituted or unsubstituted C5-C8 cycloalkyl, benzyl, or phenethyl; and R6 is p-methylbenzenesulfonate.

[0023] It is found in the development process that when R and R' in the monoguanidine salt polymer having the structure of R-NH-a-R' are not both hydrogen, the viscosity of the system during preparation is easier to control, the guanidine salt polymer is more grafted to the water-soluble polymer, and less gel is produced, and the storage stability of the obtained product is better.

[0024] In some embodiments, the biguanide salt polymer can include at least one of polyhexamethylene biguanide hydrochloride, polypropylene biguanide hydrochloride, polyaminopropyl biguanide hydrochloride, poly-[2-(2-ethoxy)-ethoxyethyl]-biguanide hydrochloride, polypropylene hexamethylene biguanide hydrochloride, polypropylene octamethylene biguanide hydrochloride, and polyhexamethylene diethylene triamine biguanide hydrochloride.

[0025] The present application also provides a preparation method of the disinfectant mother liquor, specifically comprising the following steps: mixing the raw material composition of the disinfectant mother liquor as described above, and preparing the disinfectant mother liquor through a grafting reaction.

[0026] In some embodiments, the temperature of the grafting reaction can be 40-100°C, and preferably 50-80°C.

[0027] In some embodiments, the time of the grafting reaction can be 0.5-6h, and preferably 1-3h.

[0028] In some embodiments, the grafting reaction can further comprise a step of cooling to room temperature.

[0029] In some preferred embodiments, when the guanidine salt polymer comprises a mono-guanidine salt polymer having a structure of R-NH-a-R', and R and R' are both hydrogen, the method for preparing the disinfectant stock solution comprises the following steps:

[0030] (1) mixing the guanidine salt polymer with a portion of the water, and then mixing with the dialdehyde grafting agent to obtain a mixture 1;

[0031] (2) mixing the water-soluble polymer with the remaining portion of the water, and then mixing with the mixture 1, and cooling to room temperature.

[0032] It is found in the development process that when R and R' are both hydrogen, controlling the order of addition is more conducive to avoiding the occurrence of crosslinking reaction, and there is no gel in the product.

[0033] In step (1), the temperature of the mixing is room temperature.

[0034] In step (1), the time of the mixing can be 30-60 min.

[0035] In step (1), the temperature of the mixing reaction can be 20-50°C, preferably 30-40°C.

[0036] In step (1), the time of the mixing reaction can be at least 5 min, preferably 30-60 min, and more preferably 40-45 min.

[0037] In step (2), the temperature of the mixing can be 90-95°C.

[0038] In step (2), the time of the mixing can be 2.5-4 h, preferably 3 h.

[0039] In step (2), the temperature of the mixing reaction can be 40-100°C, preferably 40-80°C, and more preferably 60°C.

[0040] In step (2), the time of the mixing reaction can be 0.5-6 h, preferably 1.5-4 h, for example 2 h.

[0041] In step (1) and step (2), the mass ratio of the portion of the water to the remaining portion of the water can be 1:(1.5-9), preferably 1:(3-5.6), for example 1:4.

[0042] The present application also provides a disinfectant stock solution prepared by the method for preparing the disinfectant stock solution as described above.

[0043] The present invention also provides a disinfectant comprising the disinfectant stock solution and diluent as described above.

[0044] In some embodiments, the content of guanidine salt polymer in the disinfectant may be 200 to 10,000 ppm.

[0045] In some embodiments, the diluent may include water.

[0046] The present invention also provides the application of the disinfectant mother liquor and / or the disinfectant as described above as raw materials in the preparation of antibacterial and disinfectant products in the field of daily chemical products.

[0047] Based on common knowledge in the field, the above-mentioned preferred conditions can be combined arbitrarily to obtain various preferred embodiments of the present invention.

[0048] In this invention, the room temperature can be 15 to 35°C, which is commonly referred to in the art.

[0049] The reagents and raw materials used in this invention are all commercially available.

[0050] The significant advantages of this invention are as follows: By grafting guanidine salt polymers onto water-soluble polymers, the resulting disinfectant mother liquor exhibits excellent antibacterial and disinfection effects, surpassing those of guanidine salt polymers at the same concentration. Furthermore, it demonstrates superior antibacterial and disinfection durability and a broader antibacterial spectrum. The disinfectant mother liquor contains a low level of free guanidine salt polymers, and because these polymers are not easily detached from the water-soluble polymers, it offers high safety and is suitable for applications with stringent safety requirements. Detailed Implementation

[0051] The present invention is further illustrated below by way of embodiments, but the invention is not limited to the scope of the embodiments described herein. Experimental methods in the following embodiments that do not specify specific conditions were performed according to conventional methods and conditions, or as selected according to the product instructions.

[0052] Unless otherwise specified, the experimental methods used in the following examples are conventional methods.

[0053] In the following examples and comparative examples, the number average molecular weight of polyvinyl alcohol is 50,000 to 110,000.

[0054] In the following examples and comparative examples, the number average molecular weight of the water-soluble starch is less than 200,000.

[0055] In the following examples and comparative examples, the number-average molecular weight of PHMB is 1500.

[0056] In the following examples and comparative examples, the number-average molecular weight of PHMG is 800.

[0057] The number-average molecular weight of the guanidine salt polymers in Examples 14-16 below is 950.

[0058] Examples 1-8 and Comparative Examples 1-5

[0059] The specific types and amounts of the components in the raw material composition for preparing the disinfectant stock solution are shown in Table 1, and the preparation process includes the following steps:

[0060] (1) The guanidine salt polymer (PHMB polyhexamethylene biguanide hydrochloride) was mixed with 15 g of water at room temperature for 30 min, and then mixed with the dialdehyde grafting agent (glutaraldehyde) at 40°C for 45 min to prepare a mixed solution 1.

[0061] (2) The water-soluble polymer was mixed with 85 g of water at a temperature of 95°C for 3 h, and then mixed with the mixed solution 1 at 60°C for 120 min. After the mixing reaction, the temperature was lowered to room temperature to prepare the disinfectant stock solution.

[0062] The preparation method of Comparative Example 1 was to mix 2.04 g of polyhexamethylene biguanide hydrochloride with 100 g of water.

[0063] Table 1

[0064]

[0065] Note: “--” in Table 1 indicates that the component is not added.

[0066] Examples 9-13 and Comparative Examples 6-10

[0067] The specific types and amounts of the components in the raw material composition for preparing the disinfectant stock solution are shown in Table 2, and the preparation process includes the following steps:

[0068] (1) The guanidine salt polymer (PHMG polyhexamethylene monoguanide hydrochloride) was mixed with 20 g of water at room temperature for 60 min, and then mixed with the dialdehyde grafting agent (glutaraldehyde) at 40°C for 40 min to prepare a mixed solution 1.

[0069] (2) The water-soluble polymer was mixed with 80 g of water at a temperature of 90°C for 3 h, and then mixed with the mixed solution 1 at 60°C for 90 min. After the mixing reaction, the temperature was lowered to room temperature to prepare the disinfectant stock solution.

[0070] The preparation process of Comparative Example 6 was to mix 2.04 parts of polyhexamethylene monoguanide hydrochloride with 100 parts of water.

[0071] Table 2

[0072]

[0073] Note: “--” in Table 2 indicates that the component is not added.

[0074] Examples 14-16

[0075] The specific types and contents of the components in the raw material composition for preparing the disinfectant mother liquor are shown in Table 3, and the preparation process comprises the following steps:

[0076] (1) The guanidine salt polymer (polyhexamethylene guanidine hydrochloride, with a structural formula of R-NH-a-R', R is hydrogen, and R' is The structural unit included in a is Mixing with 20 g of water at room temperature for 60 min to obtain a mixed solution 1;

[0077] (2) Mixing the water-soluble polymer with 80 g of water at a temperature of 90°C for 3 h, and then mixing with the mixed solution 1 and the dialdehyde grafting agent at 60°C for 90 min, and then reducing the temperature to room temperature to obtain the disinfectant mother liquor.

[0078] Table 3

[0079]

[0080] Comparative Example 11

[0081] Compared with Example 1, the only difference is that glutaraldehyde is replaced with an equal amount of 1,5-diepoxyhexane, and other conditions are the same as in Example 1.

[0082] Effect Example

[0083] 1. Determination of grafting rate and grafting efficiency of guanidine salt polymer

[0084] Take 1.0 g of the disinfectant mother liquor obtained in the above examples and comparative examples, and drop it into 20.0 g of methanol to precipitate polyvinyl alcohol and polyvinyl alcohol grafted with guanidine salt polymer (when the water-soluble polymer is water-soluble starch, after adding methanol, water-soluble starch and water-soluble starch grafted with guanidine salt polymer are precipitated), filter to remove free guanidine salt polymer, and dry the filtered product at 80°C to constant weight, weigh, and record as W1;

[0085] (2) Compared with the above examples and comparative examples, no guanidine salt polymer is added, and other substances are added in the same proportion and processed in the same way to obtain a mixed solution product, take 1.0 g, drop it into 20.0 g of methanol, precipitate polyvinyl alcohol, filter, dry the filtered product at 80°C to constant weight, weigh, and record as W0.

[0086] (3) The grafting rate of guanidine salt polymer is calculated by the formula: (W1-W0) / W1x100%, and the results are shown in Table 4;

[0087] (4) The grafting efficiency of guanidine salt polymer was calculated by the formula: (W1-W0) / the amount of guanidine salt input during preparation x 100%, and the results are shown in Table 4. The lower the grafting efficiency of guanidine salt polymer, the higher the content ratio of free guanidine salt polymer in the disinfectant mother liquor, and the poorer the safety in use. For example, when used in the field of daily chemicals, free guanidine salt polymer with low molecular weight can penetrate the human skin and penetrate into the body, causing harm to the human body. Therefore, the higher the grafting efficiency of guanidine salt polymer, the more ideal.

[0088] 2. Disinfection performance test

[0089] The disinfectant mother liquor prepared in the above examples and comparative examples was diluted by mixing with water to prepare a disinfectant with a guanidine salt polymer content of 0.5wt% in the final product. The disinfection performance was tested according to the Suspension Quantitative Method of the Disinfection Technical Specification 2002 edition, and the disinfection time was 5 min. The results are shown in Table 4.

[0090] 3. 12h skin retention and antibacterial test

[0091] The disinfectant mother liquor prepared in the above examples and comparative examples was diluted by mixing with water to prepare a disinfectant with a guanidine salt polymer content of 0.5wt% in the final product. The 12h skin retention effect was detected according to the test method of 5.1.6 of the standard WS_T650-2019, and the results are shown in Table 4.

[0092] 4. Continuous antibacterial test

[0093] The disinfectant mother liquor prepared in the above examples 1-2, example 5, example 7, examples 9-10, and examples 12, 14, and comparative examples 1 and 6 was diluted by mixing with water to prepare a disinfectant with a guanidine salt polymer content of 0.1wt% in the final product. The continuous antibacterial test was performed according to the test of 5.2.7 of the standard WS_T650-2019, and the bacterial suspension was reacted with the test carrier for 5 min. Sampling tests were performed on the 1st day and the 15th day, respectively, and the results are shown in Table 4.

[0094] Table 4

[0095]

[0096]

[0097] Note: “--” in Table 3 represents that the corresponding data was not tested.

[0098] Among them, the products prepared in comparative example 2, comparative example 4, comparative example 7 and comparative example 9 all showed partial gel phenomenon, and could not be used as disinfectants, so the above data were not tested.

[0099] The above results show that the disinfecting mother liquor prepared by the embodiment of the application has ideal antibacterial performance, and has better antibacterial and disinfecting effect, higher durability of antibacterial and disinfecting, wider antibacterial range, lower free guanidine salt polymer content in the disinfecting solution, and higher safety in use than the guanidine salt polymer with the same concentration. It is found in the research and development process that the mass ratio of the water-soluble polymer and the guanidine salt polymer and the mass ratio of the dialdehyde grafting agent and the guanidine salt polymer have great influence on the performance of the final product. When not within the limited range of the application, cross-linking reaction is prone to occur, gel is produced, the antibacterial performance is poor or the guanidine salt polymer grafting efficiency is low, and the safety in use is poor.

[0100] Finally, it should also be noted that the terms "comprising", "containing" or any other variant thereof in the present application are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements not only includes those elements, but also includes other elements not explicitly listed or inherent to such a process, method, article or device.

[0101] Although the present disclosure has been disclosed by the description of the specific embodiments of the present disclosure above, it should be understood that those skilled in the art can design various modifications, improvements or equivalents of the present disclosure within the spirit and scope of the appended claims. These modifications, improvements or equivalents should also be considered to be included in the scope of protection required by the present disclosure.

Claims

1. A raw material composition for a disinfecting stock solution, characterized by comprising, The raw material composition comprises the following components by weight: 100 parts of water, 2-10 parts of water-soluble polymer, 0.1-1 part of dialdehyde grafting agent and 1-6 parts of guanidine salt polymer; The mass ratio of the water-soluble polymer to the guanidine salt polymer is (1.5-4):1, and the mass ratio of the dialdehyde grafting agent to the guanidine salt polymer is (0.05-0.4):1; The water-soluble polymer comprises at least one of water-soluble starch, polyvinyl alcohol, polyethylene glycol and polyacrylamide, and the number average molecular weight of the water-soluble polymer is 20-200 thousand; The guanidine salt polymer is a mono-guanidine salt polymer and / or a di-guanidine salt polymer, and the number average molecular weight of the guanidine salt polymer is 500-30,000; The mono-guanidine salt polymer comprises a mono-guanidine salt polymer having a structure of R-NH-a-R'; a comprises at least one structural unit of the general formula (A), Y n - selected from the group consisting of CI - , Br - , HSO4 - , HCO3 - , H2PO4 - , or CH3COO - ; R n is selected from one or more of a structural unit having the structure of (formula 11), the structure of (formula 12), the structure of (formula 13), the structure of (formula 14), the structure of (formula 15), the structure of (formula 16), and the structure of (formula 17); In R and R', one is hydrogen, and the other is selected from hydrogen, a structural unit shown in formula (21), a structural unit shown in formula (22), a structural unit shown in formula (23), a structural unit shown in formula (24) or a structural unit shown in formula (25); R3 is C4-Ci2alkyl; R4 is C2-C4alkylene; R5 is C2-C4alkyl; R6 is p-toluenesulfonyl; and R7 is C2-C4alkyl. 12 R3 is C4-Ci2alkyl; R4 is C2-C4alkylene; R5 is C2-C4alkyl; R6 is p-toluenesulfonyl; and R7 is C2-C4alkyl. 12 R3 is C4-Ci2alkyl; R4 is C2-C4alkylene; R5 is C2-C4alkyl; R6 is p-toluenesulfonyl; and R7 is C2-C4alkyl. The di-guanidine salt polymer comprises at least one of polyhexamethylene biguanide hydrochloride, polypropylene biguanide hydrochloride, polyaminopropyl biguanide hydrochloride, poly-[2-(2-ethoxy)-ethoxyethyl]-biguanide hydrochloride, polypropylene hexamethylene biguanide hydrochloride, polypropylene octamethylene biguanide hydrochloride and polyhexamethylene diethylene triamine biguanide hydrochloride.

2. The feedstock composition of claim 1, wherein In R and R', one is hydrogen, and the other is selected from a structural unit shown in formula (21), a structural unit shown in formula (22), a structural unit shown in formula (23), a structural unit shown in formula (24) or a structural unit shown in formula (25).

3. The feedstock composition of claim 1 or 2, wherein The raw material composition satisfies at least one of the following conditions: The mass ratio of the water-soluble polymer to the guanidine salt polymer is (2-4):1; The mass ratio of the dialdehyde grafting agent to the guanidine salt polymer is (0.05-0.2):1; The dialdehyde grafting agent comprises at least one of glutaraldehyde, p-phenylenedimethanal and o-phenylenedimethanal.

4. The feedstock composition of claim 3, wherein The raw material composition satisfies: The mass ratio of the water-soluble polymer to the guanidine salt polymer is (3-4):1; The mass ratio of the dialdehyde grafting agent to the guanidine salt polymer is (0.1-0.2):1; The water-soluble polymer comprises water-soluble starch and / or polyvinyl alcohol; The dialdehyde grafting agent comprises glutaraldehyde.

5. A method of preparing a disinfecting stock solution, characterized by, The method comprises the following steps: mixing the raw material composition of the disinfectant mother liquor, and preparing the disinfectant mother liquor through grafting reaction.

6. The production method according to claim 5, wherein The preparation method satisfies at least one of the following conditions: The temperature of the grafting reaction is 40-100°C; The time of the grafting reaction is 0.5-6h; The preparation method satisfies at least one of the following conditions:

7. The production method according to claim 6, wherein The temperature of the grafting reaction is 50-80°C; The time of the grafting reaction is 1-3h. The disinfectant mother liquor is prepared according to the following preparation method:

8. The production method according to claim 6, wherein (1) mixing the guanidine salt polymer with part of the water, and then mixing and reacting with the dialdehyde grafting agent to prepare a mixed solution 1; ​ (2) mixing the water-soluble polymer with the rest of the water, and then mixing with the mixed solution 1, and then reducing to room temperature; In step (1), the guanidine salt polymer is mixed with the water for 30-60 min; In step (2), the mixing time is 2.5-4 h.

9. The production method according to claim 5, wherein When the guanidine salt polymer comprises a mono-guanidine salt polymer having the structure of R-NH-a-R', and R and R' are both hydrogen, the preparation method of the disinfectant mother liquor comprises the following steps: (1) mixing the guanidine salt polymer with part of the water, and then mixing with the dialdehyde grafting agent to prepare a mixed solution 1; (2) mixing the water-soluble polymer with the rest of the water, and then mixing with the mixed solution 1, and then reducing to room temperature; in step (2), the mixing time is 2.5-4 h.

10. The production method according to claim 8 or 9, characterized by, The preparation method of the disinfectant mother liquor satisfies at least one of the following conditions: In step (1), the mixing temperature is room temperature; In step (1), the mixing time is 30-60 min; In step (1), the mixing reaction temperature is 20-50℃; In step (1), the mixing reaction time is at least 5 min; In step (2), the mixing temperature is 90-95℃; In step (2), the mixing time is 3 h; In step (2), the mixing reaction temperature is 40-100℃; In step (2), the mixing reaction time is 0.5-6 h; In step (1) and step (2), the mass ratio of the part of the water to the rest of the water is 1:(1.5-9).

11. The production method according to claim 10, wherein The preparation method of the disinfectant mother liquor satisfies at least one of the following conditions: In step (1), the mixing reaction temperature is 30-40℃; In step (1), the mixing reaction time is 30-60 min; In step (2), the mixing reaction temperature is 40-80℃; In step (2), the mixing reaction time is 1.5-4 h; In step (1) and step (2), the mass ratio of the part of the water to the rest of the water is 1:(3-5.6).

12. The production method according to claim 11, wherein The preparation method of the disinfectant mother liquor satisfies: In step (1), the mixing reaction time is 40-45 min.

13. A disinfecting stock solution, characterized in that, The disinfectant mother liquor is prepared by the preparation method of any one of claims 5-12.

14. A disinfectant, characterized by, The disinfectant mother liquor comprises the disinfectant mother liquor of claim 13 and a diluent.

15. The disinfectant of claim 14, wherein, The disinfectant satisfies at least one of the following conditions: The content of the guanidine salt polymer in the disinfectant is 200-10000 ppm; The diluent comprises water.

16. Use of the disinfectant mother liquor of claim 13 and / or the disinfectant of any one of claims 14-15 as raw materials in the field of preparing daily chemical products for antibacterial disinfectant products.

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